Publications
Sahni, M., Ambrosett, D., Mansukhani, A., Gertner, R., Levy, D., and Basilico, C. (1999) FGF signaling inhibits chondrocyte proliferation and regulates bone development through STAT1 pathway. Genes & Dev. 13:1361-1366.
Miller, D.L., Ortega, S., Bashayan, O., Basch, R., and Basilico, C. (2000) Compensation by fibroblast growth factor 1 (FGF1) does not account for the mild phenotypic defects observed in FGF2 null mice. Mol. Cell. Biol. 20:2260-2268.
Mansukhani, A., Bellosta, P., Sahni, M., and Basilico, C. (2000) Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts. J. Cell Biol. 149:1297-1308.
Ambrosetti, D-C., Scholer, H.R., Dailey, L., and Basilico, C. (2000) Modulation of the activity of multiple transcriptional activation domains by DNA-binding domains mediates the synergistic action of Sox2 and Oct-3 on the FGF-4 enhancer. J. Biol. Chem. 275:23387-23397.
Fraidenraich, D., Iwahori, A., Rudnicki, M., and Basilico, C. (2000) Activation of Fgf4 gene expression in the myotomes is regulated by myogenic bHLH factors and by Sonic Hedgehog. Dev. Biol. 2225:392-406.
Dailey, L., and Basilico, C. (2001) Coevolution of HMG domains and homeodomains and the generation of transcriptional regulation by Sox/POU complexes. J. Cell. Physiol. 186:315-3228.
Sahni, M., Raz, R., Coffin, J.D., Levy, D., and Basilico, C. (2001) STAT1 mediates the increased apoptosis and reduced chondrocyte proliferation of mice overexpressing FGF2. Development 129:2119-2129.
Blancou, P., Vartanian, J-P., Christopherson, C., Chenciner, N., Basilico, C., Kwok, S., and Wain-Hobson, S. (2001) Polio vaccine samples not linked to AIDS. Nature 410:1045-1046.
Bellosta, P., Iwahori, A., Plotnikov, A.N., Eliseenkova, A.V., Basilico, C., and Mohammadi, M. (2001) Identification of receptor and heparin binding sites in fibroblast growth factor 4 by structure-based mutagenesis. Mol. Cell. Biol. 21:5946-5957.
Pintucci, G., Moscatelli, D., Saponara, F., Biernacki, P.R., Baumann, F.G., Biz, C., Galloway, A.C., Basilico, C., and Mignatti, P. (2002) Lack of ERK activation and cell migration in FGF-2-deficient endothelial cells. FASEB J. 16:598-600.
Laplantine, E., Rossi, F., Sahni, M., Basilico, C., and Cobrinik, D. (2002) FGF signaling targets the pRb-related p107 and p130 proteins to induce chondrocyte growth arrest. J Cell Biol 158:741-7 50.
Bellosta, P., Masramon, L., Mansukhani, A., and Basilico, C. (2003) p21WAF1/CIP1 acts as a brake in osteoblast differentiation. J Bone Min. Res. 18:81 8-826.
Dailey, L., Laplantine, E., Priore, R., and Basilico, C. (2003) A network of transcriptional and signaling events activated by FGF to induce chondrocyte growth arrest and differentiation. J Cell Biol. 161:1053-1066.
Polnaszek, N., Kwabi-Addo, B., Peterson, L.E., Ozen, M.. Greenberg, N.M., Ortega, S., Basilico, C., and Ittman, M. (2003) Fibroblast growth factor 2 promotes tumor progression in an autochthonous mouse model of prostate cancer. Cancer Res. 63:5754-5760.
Olsen, S.K,, Ibrahimi, O.A., Raucci, A., Zhang, F., Eliseenkova, A.V., Yayon, A., Basilico, C., Lindhardt, R.J., Schlessinger, J., and Mohammadi, M. (2 004)Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promsicuity. Proc. Natl. Acad. Sci. U.S.A. 101:935-940.
Raucci, A., Laplantine, E., Mansukhani, A., and Basilico, C. (2004) Activation of the ERK1/2 and p38 mitogen-activated protein kinase pathways mediates fibroblast growth factor-induced growth arrest of chondrocytes. J Biol Chem 279:1747-56.
Iwahori, A., Fraidenraich, D., and Basilico, C. (2004) A conserved enhancer element that Drives FGF4 gene expression in the embryonic myotomes is synergistically activated by GATA and bHLH proteins. Dev Biol 270:525-37.
Mansukhani, A., Ambrosetti, D., Holmes, G., Cornivelli, L., and Basilico, C. (2005) Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation. J Cell Biol. 168:1065-1076.
Dailey, L., Ambrosetti, D., Mansukhani, A., and Basilico, C. (2005) Mechanisms underlying differential responses to FGF signaling. Cytokine Growth Factor Reviews. 16:233-247.