If you are interested in participating in any of the following studies please take a look at our General Research Brochure and our Contact page. They contain useful information that will help you to make an informed decision regarding research participation and also includes a glossary of terms often used to describe our studies. If you are interested in taking part in one of the following trials, please call or e-mail us for more information.

Drug and Alcohol Dependence:

• Prescription Opiate Addiction Treatment Study (POATS)

A Two-Phase Randomized Controlled Clinical Trial of Buprenorphine/Naloxone Treatment Plus Individual Drug Counseling for Opioid Analgesic (pain killers) Dependence. No longer recruiting.

• Opiate Relapse Prevention Using Naltrexone for Parolees/Probationers

Study to examine the effectiveness of depot Naltrexone in preventing relapse in parolees and probationers with a history of opioid addiction. Currently recruiting. Please call 917-992-8651 for more information.

• Acamprosate Treatment of Methamphetamine Dependence

• Methamphetamine Brain Imaging Study

White Matter Changes in Methamphetamine Abuse.

• Varenicline Treatment in Cigarette Smokers

Placebo-Controlled Study of Varenicline Effects on Nicotine Withdrawal Followed by a Test of Smoking Topography, Reward, and Reinforcement. Currently recruiting.

• Cue-Induced Cocaine Craving Study

A Placebo-Controlled Study of Valproate Effects on Cue-Induced Cocaine Craving. No longer recruiting.

• Bupropion Treatment of Methamphetamine Dependence

NIDA-MDS-BupropionMeth-0001. Currently recruiting.

A placebo controlled trial of aprepitant for the management of opioid withdrawal in methadone maintained patients. Currently recruiting.

• Cocaine Vaccine Study

Multisite Controlled Trial of Cocaine Vaccine (5 of 6) New York University Treatment Site. Plan to begin recruitment Fall 2009.

• Brain Imaging Study of Cocaine Addiction

Functional and Structural Connectivity in Cocaine Addiction. No longer recruiting.

• Study of Vivitrol in Alcohol Dependence

Extended-release Naltrexone (Vivitrol) for Treatment of Alcohol Dependence in Urban Primary Care. Closed to patient entry.

• Patient Feedback Study

Patient Feedback Study: Feasibility of a patient-focused research study at outpatient treatment programs. Active.

• Mentorship for Alcohol Problems (MAP-Alcohol). Currently recruiting.

• Mentorship for Addiction Problems to Aid in Engagement to Treatment (MAP-Engage). Currently recruiting.

Attention Deficit Hyperactivity Disorder (ADHD):

Please view our ADHD Brochure for more information.

• Dosing Study of Concerta for the treatment of Adult ADHD

A Placebo-controlled, Double-blind, Parallel-group, Individualized Dosing Study Optimizing Treatment of Adults with Attention Deficit Hyperactivity Disorder to an Effective Response with OROS® Methylphenidate: OTTER Study.  Plan to begin recruitment Fall 2009.

• ADHD Symptom Rating Scale Study for Adolescents

Comparison of Self and Clinician Administered Ratings of Symptoms in Patients with Attention Deficit Hyperactivity Disorder (ADHD). No longer recruiting.

• Adult ADHD Treatment With Vyvanse

Effectiveness and Duration of Effect of Open Treatment in Adult ADHD Patients Treated with Lisdexamfetamine Dimesylate –LDX (Vyvanse). No longer recruiting.

• fMRI Study of ADHD and Executive Function

A Functional Magnetic Resonance Imaging (fMRI) Study of the Impact of Reward Anticipation on Executive Function in Adolescents and Adults with ADHD and Normal Controls.

• Comparison Study of Immediate Release and Extended Release Adderall

A Within-Subject Cross-over Comparison between Immediate Release and Extended Adderall. No longer recruiting.

• ADHD Treatment with Atomoxetine in a Residential Substance Abuse Treatment Facility

A 10-Week Open Label Trial of Atomoxetine for ADHD was given to Patients with Substance Abuse Disorder and ADHD at Odyssey House. No longer recruiting.

Neuroimaging:

• fMRI Study of ADHD and Executive Function

A Functional Magnetic Resonance Imaging (fMRI) Study of the Impact of Reward Anticipation on Executive Function in Adolescents and Adults with ADHD and Normal Controls.

• Brain Imaging Study of Cocaine Addiction

Functional and Structural Connectivity in Cocaine Addiction. No longer recruiting.

• Methamphetamine Brain Imaging Study

White Matter Changes in Methamphetamine Abuse.

Other States of Pathological Restlessness:

• Incidence of Akathisia in Patients Treated with Aripiprazole. No longer recruiting.

Other Ongoing Studies:

• Prazosin Treatment for Veterans with War Zone Trauma PTSD

VA Cooperative Study #563: Prazosin Treatment for Combat Trauma PTSD. Plan to begin recruitment in November 2009.

• Risperidone Consta Treatment for Veterans with Schizophrenia

VA Cooperative Study #555: Long-Acting Injectable Risperidone in the Treatment of Schizophrenia. No longer recruiting.

Healthy Controls:

• We are not currently recruiting healthy controls.