Researchers: Malcolm S. Reid, PhD and others

Current research includes a clinical lab to study the neurophysiology and pharmacology of conditioned cocaine and alcohol craving, and clinical treatment trials on experimental pharmacotherapies for drug addiction. The clinical treatment trials involve studies on opiate detoxification, cocaine addiction and smoking cessation. The studies on craving examine the quantitative and neuroanatomical EEG correlates of cocaine and alcohol craving and related anxiety/arousal in response to cue presentation. Neuroanatomical EEG mapping studies also examine the effects of an acute dose of cocaine, which may be compared and contrasted with the cue-induced responses. Cocaine addiction treatment studies also examine the association of laboratory elicited cocaine craving responses with treatment outcome. Future research interests include studies on the role of environmental conditioning in nicotine craving and reinforcement, which are studied in parallel animal and clinical models. Additional clinical projects include studies on the effects of stimulants (nicotine and cocaine) and cue exposure on neurocognitive function and impaired judgment in cocaine dependent subjects.

Current Clinical Studies