Dr. James Slater’s research interests are directed toward the practice of percutaneous coronary artery intervention and angiography. As a principle investigator in the NHLBI Dynamic Angioplasty Registry he has helped author numerous publications exploring the performance and outcome of percutaneous coronary angioplasty. In addition to research in coronary artery disease he has helped expand the use of non-surgical techniques to repair congential heart defects of the intra-atrial septum (Patent Foramen Ovale and Atrial Septal Defect). He is a principal investigator in the Closure 1 trial studying the best treatment of patients with stroke and patent foramen ovale. He has explored balloon treatment of mitral valve stenosis for many years and was recently selected along with Dr. Paul Tunick to lead NYU’s contribution to the EVEREST trial of non-surgical repair of mitral regurgitation. Other research interests include novel treatments of myocardial infarction (APEX AMI Trial) and in collaboration with Dr. Judith Hochman, optimal treatment strategies of cardiogenic shock. For the past 2 years, Dr. Slater has collaborated with Dr. Jill Jacobs of the Radiology Department to help develop active clinical and research programs in non-invasive coronary imaging using new generation CT scanners, which hold the potential to greatly change the way we image and treat atherosclerotic coronary artery disease.

Selected Publications:

1. Webb JG, Sanborn TA, Carere RG, Sleeper LA, Porway M, Koller PT, Baran KW, Slater JN, Talley JA, Buller CE, Hochman JS for the SHOCK Investigators. Interventional Management of Cardiogenic Shock after Acute Myocardial Infarction: A report from the SHOCK Registry Am Heart J 2001; 141 (6); 964-70
2. Babak AV, Kaplan RC, Slater JN, Sherman W, Ravi KL, Green SJ, Sanborn TA, Brown DL: A Propensity Analysis of the Impact of Platelet Glycoprotein llb/llla Inhibitor Therapy on In-Hospital Outcomes After Percutaneous Coronary Intervention. Am J Cardiol 2003; 91:946-950
3. Keelan PC, Johnston JM, Tulay K, Detre KM, Williams DO, Slater JN, Block PC, Holmes DR: Comparison of In-Hospital and One – Year Outcomes in Patients With Left Ventricular Ejection Fractions < 40%, 41%- 49%, and >50% Having Percutaneous Coronary Revascularization. Am J Cardiol 2003; 91: 1168-1172
4. Slater J, Selzer F, Dorbala S, Tormey D, Vlachos HA, Wilensky RL, Jacobs AK, Laskey WK, Douglas JS Jr, Williams DO, Kelsey SF: Ethnic Differences in the Presentation, Treatment Strategy, and Outcomes of Percutaneous Intervention (A Report from the National Heart, Lung, and Blood Institute Dynamic Registry) Am J Cardiol 2003; 92: 1-6. Glaser R, Selzer F, Faxon DP, Laskey WK, Cohen HA, Slater J, Detre KM, Wilensky RL: Clinical Progression of Incidental, Asymptomatic Lesions Discovered During Culprit Vessel Coronary Intervention. Circulation 2005; 111: 143-149.
5. Dzavik V, Sleeper LA, Picard MH, Sanborn TA, Lowe AM, Gin Ken, Saucedo J, Webb JG, Menon V, Slater J, Hochman JS: Outcome of patients aged >75 years In the Should we emergently revascularize Occluded Coronaries in cardiogenic shocK (SHOCK) trial: Do elderly patients with acute myocardial infarction complicated by cardiogenic shock respond differently to emergent revascularization? Interventional Cardiology 2005; 149 1128-1134