Hedgehog is required for CySC self-renewal but does not contribute to the GSC niche in the Drosophila testis

Monday, January 14, 2013

Members in the Bach Lab have shown that Hedgehog (Hh) from the Drosophila testis niche is a self-renewal factor for cyst stem cells (CySCs) and that Hh signaling does not contribute to the role of CySCs as a niche for germ line stem cells (GSCs).  This supports the model that the Hh and Jak/Stat pathways act independently within CySCs. The paper is published in the January 2013 issue of Development.  

To view the paper click here:

Hedgehog is required for CySC self-renewal but does not contribute to the GSC niche in the Drosophila testis