Northwestern University, Feinberg School of Medicine
Children's Research Center
2430 N Halsted
Chicago, IL 60614
6/99: - Left Fishell lab
11/94 - 5/99: Associate Research Scientist
NYU School of Medicine/Skirball Institute, Laboratory of Dr. Gord Fishell.
Studied dorsal ventral patterning of the embryonic telencephalon.
9/91 - 3/95: Post Doctoral Fellow
Columbia University, Laboratory of Dr. James Manley. Studied mechanisms of
9/83 - 9/90: Graduate Student
Mount Sinai School of Medicine, NY, Laboratory of Dr. Edward Johnson.
Studied myoblast differentiation.
Jhumku Kohtz joined the Department of Pediatrics, Northwestern
University/Children's Research Center as an Assistant Professor in June
1999. She is a faculty member in two graduate programs, the Northwestern
University Institute for Neuroscience (NUIN) and the Integrated Graduate
Program (IGP). Her lab is focused in two aims: 1. Studies of how forebrain
patterning depends on Shh morphogenic gradients established through
lipid-modification, 2. Studies of Evf2, ultraconserved non-coding RNA
target of Shh signaling with transcription-regulating activity. She recently
discovered that the Evf2 non-coding RNA complexes with Dlx homeodomain
proteins and that Evf2 expression is critical for balanced gene expression
in the Dlx 5/6 region. Future work includes determining the mechanism of
non-coding RNA/homeodomain interactions and their role in dosage of genes
critical for GABAergic interneurons. Studies are performed at the
biochemical, genetic and behavioral levels.