Fishell Bio
Publications & Reprints
Future Goals
Group Members
Lab Photos
Lab Protcols
Request Reagents

Jhumku Kohtz
Assistant Professor of Pediatrics.

Contact Information

Northwestern University, Feinberg School of Medicine
Children's Research Center
Developmental Biology
2430 N Halsted
Chicago, IL 60614

Office: 773-755-6358
Lab: 773-7556358
FAX: 773-755-6385

Lab Contribution

6/99: - Left Fishell lab

11/94 - 5/99: Associate Research Scientist NYU School of Medicine/Skirball Institute, Laboratory of Dr. Gord Fishell. Studied dorsal ventral patterning of the embryonic telencephalon.

9/91 - 3/95: Post Doctoral Fellow Columbia University, Laboratory of Dr. James Manley. Studied mechanisms of RNA splicing.

9/83 - 9/90: Graduate Student Mount Sinai School of Medicine, NY, Laboratory of Dr. Edward Johnson. Studied myoblast differentiation.

Current Work

Jhumku Kohtz joined the Department of Pediatrics, Northwestern University/Children's Research Center as an Assistant Professor in June 1999. She is a faculty member in two graduate programs, the Northwestern University Institute for Neuroscience (NUIN) and the Integrated Graduate Program (IGP). Her lab is focused in two aims: 1. Studies of how forebrain patterning depends on Shh morphogenic gradients established through lipid-modification, 2. Studies of Evf2, ultraconserved non-coding RNA target of Shh signaling with transcription-regulating activity. She recently discovered that the Evf2 non-coding RNA complexes with Dlx homeodomain proteins and that Evf2 expression is critical for balanced gene expression in the Dlx 5/6 region. Future work includes determining the mechanism of non-coding RNA/homeodomain interactions and their role in dosage of genes critical for GABAergic interneurons. Studies are performed at the biochemical, genetic and behavioral levels.