Sept 2007 - Team Leader, Laboratory for Neocortical Development, RIKEN Center for Developmental Biology
My research interest is to understand the developmental mechanisms of how diverse arrays of neurons are coordinated into high-functional territories. Specific questions concerning neocortical development are: What are the mechanisms by which diverse cell fate is determined in the neocortex? How are neurons precisely arranged into distinct cortical areas? To what extent does the refinement of functional areas rely on environmental inputs? I continue to explore these questions in my own laboratory employing range of techniques including genetic manipulations, recombination mediated cell-lineage tracing, and systematic approaches to identify novel molecules responsible for areal specification. The goal is to understand the mechanistic basis by which unique sensory perceptions and functional circuitries develop in the human neocortex.