is a free-living nematode that normally inhabits the soil. It is
non-pathogenic. The cell lineage is largely invariant and transparency
of the worms reveals each nucleus in the body when viewed in the
microscope at high power. This feature has allowed the entire lineage
to be traced. Genetic manipulations are well developed (both "forward"
and "reverse"). The genome is fully sequenced.
Faculty working on worms: J. Nance, D.
Fitch, J. Hubbard, F. Piano
is commonly known as the fruit fly. It has been used as a model
system in biology since being established in the laboratory of Thomas
H. Morgan in 1909. Its tremendous history provides an extensive
database of genes and mutants that has now been extended by the
complete genome sequence. Powerful forward genetics coupled with
the ability to make transgenic flies through transposable elements
provide a model system that have facilitated our understanding of
everything from body patterning to organ development to neurogenesis.
Faculty working on flies: E. Bach , J. Dasen , R.
Dasgupta , C. Desplan , R.
Lehmann, C. Rushlow, H.D. Ryoo , M. Siegal , S. Small, G. Suh , J.