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 The
Developmental Genetics (DG) training track was conceived in 1996 by faculty
members of the Department of Biology (NYU) and the Developmental Genetics
Program (NYU School of Medicine). The program combines resources into an
integrated training program that adds areas such as plant
and evolutionary biology (at NYU Biology but lacking at NYUSM) and vertebrate
developmental genetics (at NYUSM but not represented at NYU Biology).Developmental genetics carried out in model organisms has proven to be one of the major approaches leading to the discovery of the basis of disease. Discoveries in model systems such as C. elegans, Drosophila, and Arabidopsis have also led to significant advances in biotechnology. Due to shared homologies between different organisms, results obtained from genetic analysis in one model often become rapidly applicable to analysis in other organisms. Examples include the homeobox selector genes in Drosophila and the ras signaling pathway in C. elegans, which have, respectively, provided important insights into patterning and oncogenesis in mammals, including humans. As with the discovery that homeobox genes regulate patterning in Arabidopsis, there is increasing evidence that even plant and animal developmental pathways may share many mechanisms due both to common ancestry and convergence. Most of the model organisms are also the subject of intense genomic analysis, providing the raw material for future comparisons that should reveal common features of developmental processes in all organisms. |
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Sackler
Graduate Program NYU School of Medicine 550 First Avenue New York, NY 10016 (212)263-5648 sackler-info@med.nyu.edu |
NYU
Dept. of Biology Main Building, 10th Floor
100 Washington Square East, New York, NY 10003 (212) 998-8200 biology@nyu.edu |
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© 2001 New York University |
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