Clinical Trials
If you have additional questions, please contact Audrey Sorensen, RN Trials Coordination Thoracic Oncology 212-263-2562
- A randomized, double-blind, multi-center, phase III study to assess the efficacy of ZD6474 in combination with docetaxel(Taxotere) versus docetaxel ve...
Objective: To demonstrate an improvement om progression free survival in the combination of Zactima (ZD6474) with docetaxel compared with docetaxel plus placebo in subjects with locally advanced or metastasis NSCLC after failure of 1st line anti-cancer therapy.
Investigator(s): Abraham Chachoua - E5597: Phase III Chemoprevention trial of selenium supplementation in persons with resected stage I non small cell lung cancer
Objective: Use of selenium in preventing tumor growth in patients with previously resected Stage I Non Small Cell Lung Cancer. The primary objective is to evaluate the efficacy of selenium supplementation in reducing the incidence of second primary lung tumors in patients who have been treated for Stage I NSCLC with complete surgical resection. Patients are eligible for this study if they are post complete resection of stage IA or IB NSCLC who are currently free of disease.
Investigator(s): Harvey Pass - A phase II non-randomized multicenter study to evaluate the safety and efficacy of pazopanib (GW786034) as Pre-surgical therapy in treament naive subj...
Objective: To evaluate volumetric reduction in tumors using high-resolution CT scans of the thorax following treatment with Pazopanib. Pazopanib is a potent, multi-target receptor tyrosine kinase inhibitor of VEGRFR - 1, 2, 3. In preclinical experiments, pazopanib has demonstrated significant inhibitory effect in cell proliferation and inhibition of VEGF-induced angiogenesis in animal models.
Investigator(s): Harvey Pass - Phase I Open Label study of Onconase administered on days 1 and 4 weekly for three consecutive weeks of a 28 day cycle in subjects with advanced solid...
Objective: The purpose of the study is to determine whether ONCONASE, when given into the blood stream, is safe and effective in treating your cancer.
Investigator(s): Abraham Chachoua - A Breath Test for Lung Cancer
Objective: The primary objective is to demonstrate that in clinical practice, the breath test could provide a safe and non-invasive ancillary test for primary.
Investigator(s): Harvey Pass & William Rom
- A Phase III trial of lobectomy versus sublobar resection for small (<2cm) peripheral non small cell lung cancer
Objective: The objective is to determine whether disease free survival after sublobar resection (segmentectomy or wedge) is inferior to that after lobectomy in ...
Investigator(s): Harvey Pass - 109493: A double Blind, Randomized, Placebo controlled phase III study to Assess the efficacy of recMAGE-A3 + AS15 Antigen specific cancer immunothera...
Objective: Primary objective is to demonstrate the clinical efficacy to recMAGE-A3 + AS15 versus placebo in NSCLC after complete resection. Secondary objective ...
Investigator(s): Sylvia Adams - Source MdX: Lung Cancer Biomarker Study Early Detection and Prognosis
Objective: A project involving the collection of blood samples and sample related clinical data in a collaborative research project with Source MdX for an early detection and prognosis Lung Cancer Biomarker Study.