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Juan B. Grau, MD


HOSPITAL APPOINTMENTS

7/03 – present NYU School of Medicine, Department of Cardiothoracic Surgery, Attending Physician.

7/01 – 6/03 NYU Medical Center, Department of Cardiothoracic Surgery, Department of Surgery, Cardiothoracic Fellow.

4/00 - 6/01 Bellevue Hospital Center, Trauma and Shock Unit, Surgical Intensive Care Unit, Department of Surgery, NY, NY. Attending Surgeon, Advance Trauma Life Support, Instructor.

9/99 - 4/00 Hospital Ruber Internacional, Department of Cardiothoracic Surgery, Madrid, Spain. Attending Surgeon.

EDUCATION AND TRAINING

7/01 – 6/03 NYU Medical Center, Department of Cardiothoracic Surgery, Department of Surgery, New York. NY. Cardiothoracic surgery fellow.

9/99 – 4/00 Hospital Ruber Internacional, Department of Cardiothoracic Surgery and Department of Intensive Care Medicine, Madrid, Spain. Attending Surgeon and Clinical Fellow.

7/96 - 9/99 NYU Laboratory of Developmental Biology and Repair.

New York, NY. Research fellow. Organogenesis group.

7/97 - 7/98 NYU Medical Center, Department of Surgery, New York, NY. Executive Chief Resident. General Surgery Residency.

7/93 - 7/97 NYU Medical Center, Department of Surgery, New York, NY. General Surgery Internship and Residency.

7/92 - 7/93 Maimonides Medical Center, Department of Pediatrics. Brooklyn, NY. Intern, Department of Pediatrics.

6/91 - 6/92 Animal Laboratory Research Unit, Department of Plastic and Reconstructive Surgery, Ramon y Cajal Hospital, Madrid, Spain. Microvascular Research Fellow.

9/84 - 6/90 Alcala de Henares University, School of Medicine, Madrid, Spain. MD degree.

Graduated with honors.

9/80 - 6/84 Luis Vives High School, Palma de Mallorca, Baleares, Spain.

AWARDS AND HONORS

2000 White House Medical Unit Certificate of Commendation

1998 White House Medical Unit Certificate of Appreciation.

1991 Outstanding Performance as Medical Officer Award, Special Operations Forces NATO.

1990 Graduated with honors from Alcala de Henares University, School of Medicine. Madrid, Spain.

1988 Outstanding Academic Achievements Award. Ramon y Cajal Hospital, Madrid, Spain.

MILITARY SERVICE

1/91 - 9/91 Second Lieutenant, Special Operations Forces NATO, served during Gulf War.

7/88 - 1/89 Cadet, Military Academy, NATO Special Operations Forces Training Program for Officers.

SOCIETY MEMBERSHIPS

American Medical Association

Associate Fellow, American College of Surgeons
Society of Laparo-endoscopic Surgeons

Society of Thoracic Surgery

New York Society of Thoracic Surgery

TEACHING AND RESEARCH EXPERIENCE

7/03 – present Assistant Professor of Surgery (tenure track), New York University School of Medicine.

7/01 – 6/03 Clinical Instructor of Surgery, New York University School of Medicine.

2/01 – 6/01 Assistant Professor of Surgery (tenure track), New York University School of Medicine.

4/99 – 2/01 Clinical Instructor in Surgery (tenure track), New York University School of Medicine.

7/96 – 9/99 Research Fellow. New York University Laboratory of Developmental Biology and Repair.

7/96 – 9/99 Clinical Instructor in Surgery. New York University School of Medicine.

7/94 - 7/96 Teaching Assistant in Surgery. New York University School of Medicine.

7/92 - 7/93 Teaching Assistant in Pediatrics. State University of New York at Brooklyn. Maimonides Medical Center and Coney Island Hospital.

9/91 - 6/92 Graduate Student. Alcala de Henares University School of Medicine, Department of Plastic Surgery.

1/91 - 9/91 Instructor Medical Officer. Cardiopulmonary resuscitation and emergency procedures, course for medics. Special Operations Forces, NATO.

6/90 - 1/91 Graduate Student. Alcala de Henares University School of Medicine, Department of Plastic Surgery.

9/88 - 9/89 Student Researcher. Research Project in Otorhinolaryngology and comparative Zoology entitled: "Comparative analysis of the hearing system of aquatic species and land mammals".

ADMINISTRATIVE AND COMMITTEE RESPONSIBILITIES

2003 – present Recruiting and Admissions Committee, Thoracic Surgery Residency Program. NYU Medical Center.

1997 - present Member Housestaff Committee, Department of Surgery, NYU Medical Center.

1997 - present Recruiting and Admissions Committee, General Surgery Residency Program. NYU Medical Center.

1988 - 1990 President, Alcala de Henares University, School of Medicine, Madrid, Spain.

1988 - 1990 Recruiting and Admissions Committee, Alcala de Henares University, School of Medicine, Madrid, Spain.

1984 - 1986 Human Anatomy Laboratory and Research Instructor, Alcala de Henares University, School of Medicine, Madrid, Spain.


PUBLICATIONS

1) Munoz Tuero* LM and Grau* J. Aportaciones a las estadisticas medico-forenses de clinicas e institutos anatomico-forenses. Revista Espanola de Medicina Legal, 50-51: 108-113 (1987).

2) J. B. Grau, N. M. Rowe, D. Chau, A. Mamureanu, M. T. Longaker, D. Tumbull, G. K. Gittes. Ultrasound backscatter microscopy guided injection: a vehicle for in utero cardiac gene therapy during early organogenesis. American College of Surgeons, Surgical Forum, 49, (1998).

3) B. J. Mehrara, H. Fernandez, D. Chau, J. Sagiroglu, D. Steinbrech, H. Ueno, J. B. Grau, G. Gittes, M.T. Longaker. Adenoviral mediated transmission of a dominant negative truncated TGF-b receptor inhibits in vitro mouse cranial suture fusion. American College of Surgeons, Surgical Forum, 49, (1998).

4) M. T. Longaker, B. J. Mehrara, D. Steinbrech, N. Rowe, M. Dudziak, J. B. Grau, J. G. McCarthy, G. K. Gittes. Gene expression during mandibular distraction osteogenesis. American College of Surgeons, Surgical Forum, 49, (1998).

5) H. Fernandez, B J. Mehrara, P. Saadeh, D Steinbrech, J. B. Grau, G. K. Gittes, M. T. Longaker. Adenoviral mediated TGF-b gene therapy of osteoblasts in vitro. American College of Surgeons, Surgical Forum, 49, (1998).

6) T. Maldonado, A. Kadison, C. Crisera, J. Grau, S. Alkasab, M. Longaker, G. Gittes. The ontogeny of activin B and follistatin in developing embryonic mouse pancreas: implications for lineage selection. Journal of Gastrointestinal Surgery, May 1999.

7) Grau, J, Crisera, C., Maldonado, T., Kadison, A., Alkasab, S., Li, M., Longaker, M., Gittes, G. Manipulation of the developing pancreas to identify a novel pancreatic stem cell expressing endocrine and exocrine markers. American College of Surgeons. Section: Transplantation and Associated Immunology, Surgical Forum, 50 (1999).

8) Rose, M., Maldonado, T., Grau, J., Crisera, C., Kadison, A., Li, M., Alkasab, S., Longaker, M., Gittes, G. Laminin exposure defines a critical time window for pancreatic duct differentiation from undifferentiated pancreatic precursor cells. American College of Surgeons, Section: Gynecology and Obstetrics. Surgical Forum, 50, (1999)

9) Breslow, G., Kadison, A., Crisera, C., Maldonado, T. Grau, J., Li, M., Alkasab, S., Longaker, M., Gittes, G. Formation of pancreatic ducts: relationship to a unique model of pancreatic duct development with in vivo validation. American College of Surgeons, Section: Alimentary, Surgical Forum, 50 (1999).

10) Chou, D, Crisera, C, Grau, J., Maldonado, T., Kadison, A., Li, M., Alkasab, S., Longaker, M., Gittes, G. Ultrasound backscatter microscopy: targeting of internal solid organs in the early-gestation mouse embryo. American College of Surgeons, Section: Gynecology and Obstetrics, Surgical forum, 50 (1999).

11) Li, M., Crisera, C., Maldonado, T., Kadison, A., Grau, J., Alkasab, S, Longaker, M., Gittes, G. Laminin is a critical determinant of endocrine versus exocrine lineage selection in the embryonic pancreas. American College of Surgeons. Section: Alimentary, Surgical Forum, 50 (1999).

12) Alkasab, S., Crisera, C., Maldonado, T., Kadison, A., Li, M., Grau, J., Longaker, M., Gittes, G. Differential analysis of normalized cDNA pools: high mobility group-4 protein is a transcriptional complex regulator upregulated in embryonic pancreatic mesenchyme. American College of Surgeons. Section: Pediatric Surgery, Surgical Forum, 50 (1999).

13) Crisera*, C., Grau*, J., Maldonado, T., Kadison, A., M., Longaker, M., Gittes, G. A novel non-viral, non-toxic, and highly efficient mechanism for the introduction of genes into tissues. American Pediatric Surgical Association, May 1999.

14) Crisera, C., Maldonado, T., Kadison, A., Grau, J., Alkasab, S., Longaker, M., Gittes, G. Regulation of exocrine and endocrine differentiation in the developing pancreas via TGF-beta. Meeting American Diabetes Association. June 1999

15) C. Crisera*, J. Grau*, T. Maldonado, A. Kadison, M. Longaker, G. Gittes. Defective Epithelial- Mesenchymal Interactions Dictate the Organogenesis of Tracheo-Esophageal Fistula. Journal, Pediatric Surgery International, 1999.

16) EAST Multi-Institutional HVI Research Group. Blunt Hollow Viscus Injury (HVI) and Small Bowel Injury (SBI): Prevalence, Mortality, and Morbidity. Results from a large multi-institutional study. Journal of Trauma, Injury, Infection and Critical Care. December 2001.

17) EAST Multi-Institutional HVI Research Group Diagnosis Blunt Small Bowel Injury (SBI): An Analysis of the Clinical Utility of Computerized Tomography (CT) Scan from a large multi-institutional trial. Journal of Trauma, Injury, Infection and Critical Care. December 2001.

18) EAST Multi-Institutional HVI Research Group Motor Vehicle Crash (MVC) Abdominal Seatbelt Marks as risk factors for perforating small bowel injury (SBI): Results from a large multi-institutional study. Journal of Trauma, Injury, Infection and Critical Care. December 2001.

19) EAST Multi-Institutional HVI Research Group Current Diagnostic Approaches Lack Sensitivity in the Diagnosis of Perforating Blunt Small Bowel Injury (SBI): Findings from a large multi-institutional trial. Journal of Trauma, Injury, Infection and Critical Care. December 2001.

20) J. B. Grau, B. Rinker, S.Gurdhip, A. Kim, E. Newman. Acute appendicitis secondary to metastatic carcinoma of the prostate. Contemporary Surgery. 58: 518-521 (2002).

21) P. Saunders, J.B. Grau, C. Chen, M. Zervos, C. Schwartz, M.D., S. Colvin, B. Rosenzweig*, G. Ribakove. Localized Pericardial Hematoma Presenting with Acute Hypoxemia. In press. Annals of Thoracic Surgery.

PRESENTATIONS

1) Gene expression during mandibular distraction osteogenesis. Presented at the 1998 American College of Surgeons Annual Meeting.

2) Adenoviral mediated TGF-b gene therapy of osteoblasts in vitro. Presented at the 1998 American College of Surgeons Annual Meeting.

3) Ultrasound backscatter microscopy guided injection: a vehicle for in utero cardiac gene therapy during early organogenesis. Presented at the 1998 American College of Surgeons Annual Meeting.

4) Adenoviral mediated transmission of a dominant negative truncated TGF-b receptor inhibits in vitro mouse cranial suture fusion. Presented at the 1998 American College of Surgeons Annual Meeting.

5) A novel non-viral, non-toxic, and highly efficient mechanism for the introduction of genes into tissues. Presented at the 1999 American Pediatric Surgical Association. Annual Meeting.

6) Defective Epithelial- Mesenchymal Interactions Dictate the Organogenesis of Tracheo-Esophageal Fistula. Presented at the 12th International Symposium of Paedriatic Surgical Research. September 3rd, 4th 1999, Brussels.

7) Blunt Hollow Viscus Injury (HVI) and Small Bowel Injury (SBI): Prevalence, Mortality, and Morbidity. Results from a large multi-institutional study. Presented at the fifteenth Annual Scientific Session of the EAST, January 2002, Orlando Florida.

8) Diagnosis Blunt Small Bowel Injury (SBI): An Analysis of the Clinical Utility of Computerized Tomography (CT) Scan from a large multi-institutional trial Presented at the fifteenth Annual Scientific Session of the EAST, January 2002, Orlando Florida.

9) Motor Vehicle Crash (MVC) Abdominal Seatbelt Marks as risk factors for perforating small bowel injury (SBI): Results from a large multi-institutional study. Presented at the fifteenth Annual Scientific Session of the EAST, January 2002, Orlando Florida.

10) Current Diagnostic Approaches Lack Sensitivity in the Diagnosis of Perforating Blunt Small Bowel Injury (SBI): Findings from a large multi-institutional trial. Presented at the fifteenth Annual Scientific Session of the EAST, January 2002, Orlando Florida.

11) Minimally Invasive approach for severe mitral regurgitation in a reoperative setting with severely depressed LVEF, a new alternative to traditional approaches. Presented at the meeting of The New York Society of Thoracic Surgery. February 2003, New York, New York.

BOOK CHAPTERS

H.L.Pachter, J.B. Grau. “ The Current Status of Splenic Preservation”. Mosby’s Advances in Surgery, Volume 34, 2000.