MASTERS OF SCIENCE IN CLINICAL INVESTIGATION
K30 PROGRAM: TRANSLATIONAL MEDICINE
ABOUT THE PROGRAM
The rapid strides and advancement of biomedical discoveries
present an opportunity for clinical care to further improve upon disease
prevention, diagnosis, and management. The goal of this training program
is to train clinician-scientists in the skills necessary to translate
scientific discoveries to clinical settings, to determine the efficacy
and outcomes of new and established therapy and identify, using epidemiologic
and statistical tools, the health problems of the future. The program
is intended for persons who have completed residency training in a clinical
department.
PROGRAM ELEMENTS
Course Descriptions
Clinical Research Methods
This course reviews core epidemiologic and research principles,
providing students with the basic building blocks for developing their
knowledge and skills in conducting clinical research.
Introduction to Biostatistics
This course involves the introduction to probability and statistical
methods utilized in the analysis and interpretation of experimental and
epidemiological data with applications in biology, medicine, and the
health sciences.
Advanced Epidemiology
This course is designed to introduce students in all fields
of public to the background, basic principles and methods of public health
epidemiology. Topics covered include: measures of disease frequency and
risk; epidemiologic study designs, both experimental and non-experimental;
understanding bias; and measures of effect and association. In addition,
students will develop skills to read, interpret and evaluate health information
from published epidemiological studies and mass media sources.
Developing New Drugs
The overall goal of this course is to provide an overview of
new drug development to entry-level professionals in the medical sciences.
Seminars consist of a combination lecture and discussion, and will included
invited lecturers from both the academic and private sector. Completion
of this course will enable each participant to 1) learn the vocabulary
and principles of new drug development 2) assess the non-clinical background
of a drug, 3) learn practical skills for interacting with regulatory
agencies during the course of new drug development, and 4) discuss the
financial and marketing issues behind new drugs.
Integrative Seminar
This weekly conference over two years will be a forum for review
of important issues in Clinical Research and for presentation of research
projects by the students.
- Year 1: Will cover Survival Techniques for Young Investigators in Biomedical Research followed by a two-part series on the History of Medicine.
- Year 2: Will address Skills and Strategies for Grant Writing, Identifying Funding Sources, Manuscript Preparation and Publication; and Scientific Presentation Skills.
Scientific Integrity and Responsible Conduct of
Clinical Research
This course is required by the NYU School of Medicine and provides
important insights into general scientific ethics, regulatory
responsibilities, ethical consideration of human subjects,
and research reporting and intellectual property.
Clinical Trials Design
The goals of this course include: understanding the study question
and the significance of addressing the question; identifying
eligibility criteria; describing the intervention; selection
of outcome measures including power and sample size calculations;
and developing an effective analysis plan.
Biomolecular Medicine
The specific objectives of the course are to use a “case-based” approach
to the uses and pitfalls of such technologies as gene microarrays,
proteomic analysis, knockout and transgenic mice, high throughput
screens for drug targets, siRNA and flow cytometry.
Medical Informatics
This course will serve as an introduction to Medical Informatics,
which is the interdisciplinary science of information management
in Medicine.
Grant Writing
This course provides intense didactic information on the development
of grant applications to the US Public Health Service. After
reviewing research design issues briefly, the course provides
instruction on the development of a research abstract, aims,
background, preliminary studies, methods, human subjects
protection issues, budgets and budget justification, and
forms. Following the didactic sessions which are interactive,
the students are to develop a complete R01 application using
a standard NIH format within 30 days of the start of the
course. Following this, a didactic session covers peer review,
and students are assigned as scientific peer reviewers for
submitted applications
Mentored Research Project
The most critical component of this degree program is the
opportunity for trainees to apply what they are learning in
class in a mentored research project. Each trainee will be
mentored at a number of levels. They will work most closely
with a research mentor within their Division who will supervise
the development and implementation of the study. In regular
meetings, they will plan the design and troubleshoot the progress
of the project.
Each trainee will also meet, every six months, with the program
executive committee. Prior to this meeting, the committee will
seek an update of the trainee’s progress from the research
mentor. The goals of these periodic meetings are to establish
and review individual learning goals, plan choice of elective
courses, review research progress, and troubleshoot programmatic
issues.
Finally, peer mentoring will occur in monthly works in progress
presentations during the Integrative Seminar. Trainees will
benefit from the focused feedback from the group and develop
their own skills at critical review and constructive feedback
of research protocols.
Eligibility and Admissions
Upon entrance to the program, an applicant must be:
- Board Eligible or Certified in a Clinical Specialty
- An active participant in clinical investigation
- Currently licensed to practice medicine in New York State
Application deadline: February 19, 2010
Curriculum
This Master's program curriculum consists of a total of 36
credits, as outlined below. Courses are taught by faculty
at the School
of Medicine, the Wagner
Graduate School of Public Service and the Graduate
School of Arts and Sciences.
|
Term |
Course Title |
Credits |
Year 1 |
Summer |
|
3 |
Fall |
|
3 |
|
Spring |
|
0 |
|
Year 2 |
Fall |
|
3 |
Spring |
|
1 |
|
|
|
|
36 |
Schedule
Please see below for an outline of the course and activity
schedule:
First Year (July – June)
Summer:
Courses Tuesday and Thursday mornings, Thursday afternoons
Fall & Spring:
Courses Wednesdays (all day), Thursday afternoons (for some)
Second Year (September – June)
Fall:
Courses Wednesdays (all day), Thursday afternoons (for some)
Spring:
Courses Wednesdays (all day), Thursday afternoons (for some),
2-3 evenings per week for Grant Writing course which lasts
for 3 weeks in January
