CTSI Population Health Resource

The primary objective of the CTSI’s PHR initiative is to advance research that promotes widespread dissemination and adoption of healthcare interventions whose efficacy has been demonstrated in clinical trials or other rigorously designed studies. Such research encompasses what is often referred to as effectiveness (as opposed to efficacy) research, incorporating elements of bedside-to-clinic (T2, or second phase translational research) and clinic-to-population (T3) research with a primary focus on defining strategies to maximize dissemination, adoption and sustained implementation of effective interventions.

The CTSI’s PHR initiative is thus focused on the interface of the delivery of clinical care by urban healthcare delivery systems such as ours and the health of the clinical and community populations served. The CTSI’s PHR resource will focus specifically on advancing research with population-level impact by: 1) defining core baseline and outcome measures for routine inclusion across the diverse array of current and future population health-oriented research initiatives at NYU’s schools; 2) creating large-scale observational “virtual cohort” studies to define the impact of health systems interventions on health outcomes among the diverse patient population served by NYC's municipal hospital system; 3) collaborating with the CHIBI in building clinical research databases that integrate key healthcare utilization and outcome data with clinical, genomic and community-level compliant datasets; 4) harnessing population genetics approaches to target prevention and tailor chronic disease interventions to reflect patient level risks; 5) offering expert consultation and collaboration to CTSI investigators to apply to their own work the science of optimizing its dissemination, adoption and sustained implementation; 6) training new investigators skilled in the science of implementation and dissemination research (e.g., NYU’s CDC-funded Fellowship in Medicine and Public Health Research); and, 7) integrating efforts across disciplines, including health economics, informatics, clinical epidemiology, biostatistics and behavioral health, to define readily disseminable system- and community-level interventions to improve health promotion, disease prevention and chronic illness care in diverse urban populations.

Close integration exists between PHR and related CTSI initiatives. The Community Engagement Core (CEC), by fostering community participation in identifying health and healthcare disparities and in defining resulting research agendas, is a key partner in setting PHR research priorities. PHR investigators will work closely with CEC colleagues in planning and implementing research on how best to advance dissemination of effective measures into community settings.

Summary of PHR deliverables:

For more information contact:

Laura Huben
laura.huben@nyumc.org
212-263-2938