Clonidine is often used to reduce blood pressure as well as to counter symptoms that occur during withdrawal from alcohol and other addictive substances.

 

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Coenzyme Q10 (CoQ10)  

Supplementation Possibly Helpful

There is some evidence that clonidine might impair the body's ability to manufacture the substance coenzyme Q 10 (CoQ 10 ). 1 However, it has not yet been shown that CoQ 10 supplements offer any particular benefit to those taking this medication.

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Yohimbe  

Probable Dangerous Interaction

If you are taking clonidine, it is not safe to take yohimbe. 2

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Coleus forskohlii  

Theoretical Interaction

The herb Coleus forskohlii relaxes blood vessels and might have unpredictable effects if combined with clonidine.