Below is a list of Program Faculty and their Research
Interests.
Click on their Names or Research Interests to learn more about them.
In the Department of Biochemistry |
| Dafna Bar-Sagi, Ph.D.
| |
Signal Transduction In Growth Control And Cancer |
| James Borowiec, Ph.D.
| |
Regulation of Cellular Checkpoints and DNA Repair in Higher Eukaryotes |
| Tony Huang, Ph.D.
| |
Regulation of Ubiquitination and Deubiquitination in DNA Repair and Cancer Susceptibility Pathways |
| Hannah L. Klein, Ph.D.
| |
Genes Involved in Protection Against Genomic
Instability From DNA Damage;
Regulation of the Response to
DNA Damage;
Role of Cohesins and Centromeres in
Recombination and Repair |
| Xiangpeng Kong, Ph.D.
| |
Immunology & Pathogenesis
UPEC invasion of urothelium - host-pathogen interactions in urinary tract
infection (UTI);
Structure-based HIV vaccine design |
| Evgeny A. Nudler, Ph.D.
| |
RNA Polymerase as a Molecular Machine: How It Moves, Responds to Elongation Factors and
Terminates;
The Role of the Heat Shock Response in Tumorigenesis;
New Virulence Factors and Antimicrobial Targets in Bacillus anthraces and Other Pathogens |
| Danny Reinberg, Ph.D.
| |
Regulation of Gene Expression in Eukaryotic Cells |
| Edward B. Ziff, Ph.D.
| |
Regulation of AMPA-type Glutamate Receptors at Synapses;
Mechanisms of Synaptic Plasticity; Synapse Architecture; the Biochemical Basis of Behavior Formation;
Trafficking of AMPA-type Glutamate Receptors at Synapses- Actin and the Biogenesis of Dendritic Spines;
The Pharmacology of Neuroprotection;
Neurodegenerative Diseases, Including Alzheimer's Disease and ALS; |
In
the Department of Cell Biology |
| Mary Helen Barcellos-Hoff, Ph.D.
| |
How Multicellular Processes Are Disrupted During the Progression From Normal To Neoplastic. |
| Moses Chao, Ph.D.
| |
Signal Transduction Mechanisms of Receptor Tyrosine Kinases:
EGF/Neuregulin, NGF, VEGF and Ephrin Families;
Trophic Factors; Synapse Formation; Synaptic Vesicle Recycling and Post-synaptic Ion Channel Function;
Receptor Endocytosis; Endosomal Protein Trafficking and Signaling; ER-ERGIC-Golgi Secretory Mechanisms |
| Pamela Cowin, Ph.D.
| |
Cell
Adhesion and Wnt Signaling |
| Edward A. Fisher, Ph.D., M.P.H., M.D.
| |
The
cell biology of hepatic lipid and lipoprotein metabolism;
The molecular biology of vascular diseases |
| Alan B. Frey, Ph.D.
| |
T Cell Immune Responses;
Regulation of Signal Transduction in Tumor-Infiltrating CD8+ T Cells |
| Gert Kreibich, Ph.D.
| |
Synthesis,
Assembly and Sorting of Membrane Proteins |
| Paolo Mignatti, M.D.
| |
Growth
Factors and Proteinases in Tumor Invasion and Angiogenesis |
| George Miller, M.D.
| |
Tumor Immunology in Cancers of the Liver and Pancreas |
| Kathyrn Moore, Ph.D.
| |
The Role of the Innate Immune System in Sterile Inflammatory Conditions and Host Defense |
| John S. Munger, M.D.
| |
Regulation
of Pulmonary Inflammation and Fibrosis |
| Ralph Nixon, Ph.D., M.D.
| |
Molecular Mechanisms of Alzheimer's Disease |
| Mark Philips, M.D.
| |
How Localization Affects the Signaling Output of Ras and Rho Proteins;
Ras Pathway in Human cancers; Characterization of Icmt, the Enzyme that Methylates Ras, as a Potential Target for Anti-cancer Drug Discovery;
Post-translational Processing and Trafficking of Ras and Related CAAX Proteins;
Ras and Rap1 Signaling Pathways in Lymphocytes |
| Daniel B. Rifkin, Ph.D.
| |
Mechanisms
of Cell Invasion |
| Hyung Don Ryoo, Ph.D.
| |
Regulation of Stress Response and Apoptosis in Drosophila;
Regulation of Apoptosis During Drosophila Development |
| David D. Sabatini, M.D., Ph.D.
| |
Protein
Sorting in Eukaryotic Cells |
| James L. Salzer, M.D., Ph.D.
| |
Elucidation of the Intracellular Signaling Pathways of Myelination and
Demyelination;
Ion Channel Targeting and the Molecular Organization of Axons in Myelinated Nerves |
| Marcus Schober, Ph.D.
| |
Stem Cells in Tissue Homeostasis and Carcinogenesis |
| Greg Suh, Ph.D.
| |
Neural Circuits That Control Aversion and Appetitive Behaviors |
| Tung-Tien Sun, Ph.D.
| |
Structure, Function and Disease Implications of Urothelial Membrane Plaques |
| Jessica E. Treisman, Ph.D.
| |
Cell-Cell Signaling, Cell Fate Determination, and Neuronal Connectivity in the Drosophila Eye |
| E. Lynette Wilson, Ph.D.
| |
Biology
of Stem Cells |
In the Department
of Chemistry |
| Paramjit Arora, Ph.D.
| |
Design and Synthesis of Small Molecule Ligands for Sequence-specific Recognition of DNA;
Small Molecule Inhibitors of Protein-protein Interactions |
| Kent Kirshenbaum, Ph.D.
| |
Bioorganic Chemistry, Biomimetic Chemistry, Protein Conformation and Dynamics, Macromolecular Design |
| Lara K. Mahal, Ph.D.
| |
Bioorganic Chemistry, Biomimetic Chemistry, Protein Conformation and Dynamics, Macromolecular Design |
In the Department
of Medicine |
| Mario Delmar, M.D.
| |
Molecular Mechanisms of Ccardiac Arrhythmias, With Special Focus on the Role of Intercellular Communication in Controlling Heart Rhythm |
| Carlos Fernández-Hernando, Ph.D.
| |
Cholesterol Metabolism and Atherosclerosis |
| Yajaira Suarez, Ph.D.
| |
Regulation of Endothelial and Macrophage Functions by microRNAs |
In the Department
of Microbiology |
| Joel Belasco, Ph.D.
| |
Post-Transcriptional
Gene Regulation |
| Lisa Dailey, Ph.D.
| |
Transcriptional Regulation in Embryonic Stem Cells and Early Development |
| Nathaniel R. Landau, Ph.D.
| |
Mammalian Cell Resistance To Viral Infections Through Innate or Intrinsic Immunity |
| Jennifer Philips, M.D., Ph.D.
| |
How Mycobacteria Survive in Macrophages |
| Robert Schneider, Ph.D.
| |
Altered
Regulation of Gene Expression in Carcinognesis and Cell Stress |
| Naoko Tanese, Ph.D.
| |
Chromatin and Regulation of Eukaryotic Gene Transcription
;
Role of Huntington's Disease Protein in Post-transcriptional Pathways |
| Derya Unutmaz, M.D.
| |
The Molecular Machinery of T Cell Activation, Differentiation, Survival and its Exploitation by HIV |
| Angus Wilson, Ph.D.
| |
Viral pathogenesis; Herpesviruses; Regulation of the Lytic-Latent Switch; Control of Viral and Cellular Gene Expression; Kaposi's Sarcoma-associated Herpesvirus (KSHV); Herpes Simplex Virus (HSV); Virus-Host Interactions |
In
the Department of Pathology |
| Iannis Aifantis, Ph.D.
| |
Molecular Mechanisms Controlling Hematopoietic Stem Cell (HSC) Self-renewal, Differentiation and Transformation |
| Michael Dustin, Ph.D.
| |
Imunological Synapse Formation;
Coordination of the Immune Response by Chemokines:
Biophysics of Adhesion Molecule Interactions:
Regulation of LFA-1 Activation:
In vivo Imaging of T Cell migration and Activation |
| Brian D. Dynlacht, Ph.D.
| |
Controls That Govern Mammalian Cell Cycle Regulation;
Transcription and Epigenetic Regulators of Cell Growth
and Differentiation |
Stefan Feske, M.D.
| |
The Mechanisms Underlying Calcium Signaling Pathways in Lymphocytes and the Role They Play for Immune Function in vitro and in vivo |
| Eva Hernando-Monge, Ph.D.
| |
Identification of the Cell of Origin and the Stage of Cell Differentiation in which Transforming Events Occur, Determining the Biology of the Tumor;
Characterization of the Molecular Pathways Required for Tumor Progression |
| Michelle Krogsgaard, Ph.D.
| |
Novel Imaging and Biophysical Methods to Understand the Structure;
Function of T-Cell Recognition and Mechnisms of T-Cell Responses To Self |
| David Levy, D.Ch., Ph.D.
| |
Signal Transduction, Gene Expression, Innate Immunity, Growth Control |
| Michele Pagano, M.D.
| |
Regulation
of the Mammalian Cell Cycle
and its Deregulation in Cancer |
| Angel Pellicer, M.D., Ph.D.
| |
The Physiologic Function of the Ras Genes and Their Role in Malignant Development |
| Susan Schwab, Ph.D.
| |
Lymphocyte Trafficking, Inflammation, Angiogenesis, Sphingosine-1-phosphate |
| Susan Smith, Ph.D.
| |
Molecular
Basis of Telomere Function |
| E. Sergio Trombetta, Ph.D.
| |
Cellular and Molecular Mechanisms of Immunoregulatory Functions of Dendritic Cells |
In the Department of Pharmacology |
| Timothy J. Cardozo, M.D., Ph.D
| |
Structure-based Drug and Vaccine Design; Modeling of Membrane Protein Structure |
| Gregory David, Ph.D
| |
Chromatin Modifications in Development and Oncogenesis |
| Susan K. Logan, Ph.D.
| |
Cross Talk Between Steroid Hormone Receptors and Cytokine
and Growth Factor Stimulated Signal Transduction Pathways;
Androgen Receptor Regulation of Gene Expression;
Androgen Regulation of Male Development;
Regulation of Androgen Receptor Signaling Through Receptor Modification and Interaction With Cofactors;
The Role of the Androgen Receptor in Prostate and Breast Cancer |
| Herbert H. Samuels, M.D.
| |
Regulation of Gene Expression by Nuclear Hormone Receptors |
In the Department of Physiology |
| Jeremy S. Dasen, D. Phil., Ph.D.
| |
Defining the Developmental Programs That Direct the Assembly of Neural Circuits |
| Stephen D. Ginsberg, Ph.D.
| |
Neurodegeneration, Single Cell RNA Analysis, and Lesion-induced Synaptic Plasticity |
| Bernardo Rudy, M.D., Ph.D.
| |
Molecular Studies of Potassium Channels |
