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The Brain Research Laboratories (BRL) is a division of the Department of Psychiatry at New York University School of Medicine under the direction of Drs. E. Roy John and Leslie S. Prichep. Drs. John and Prichep are also Research Scientists at the Nathan S. Kline Institute for Psychiatric Research (NKI).

Currently, the BRL team includes Psychologists, Psychopharmocologists, specialized electrophysiological technicians, mathematicians, database specialists and computer scientists.

During the 30 years of its existence, the BRL staff has been engaged in the following activities:

  1. Study of brain processes mediating learning, memory and cognition;
  2. Development of new mathematical methods and biomedical computing systems to analyze QEEG and ERP data;
  3. Studying the effects of drugs on brain electrical activity and integrating this approach with the design of optimized interventions which move the brain toward the normal space.
  4. Building the largest  quantitative electrophysiological (QEEG and ERP) database in the world;
  5. Developing algorithms using QEEG for objective classification as an adjunct to diagnoses of psychiatric patients.
  6. Performing cluster analyses for sub-typing within psychiatric diagnoses; and demonstrating the relationship between such subtypes and treatment response;
  7. Development of New Technology, including Neurobiological Computer Systems for Intraoperative Monitoring of Depth of Anesthesia, Neurosurgical or Cardiovascular Surgical Monitoring or Assessment of Brain Functions in ADHD, Dementia, Chronic and acute Pain, Traumatic Brain Injury or Cerebrovascular Accidents, and methods for 3-Dimensional QEEG-based Source Localization and Brain Imaging;
  8. Construction of theories of the physiological bases of anesthetic action and of neural processes mediating the construction of subjective experience and consciousness. Based upon such theroies, innovative methods of aggressive treatment for disorders of consciousness. These methods are being applied to patients in persistent vegatative state, minimal conscious state and to children with autisic spectrum disorders. ;
  9. Operating the Neurometric Evaluation Service to provide clinical EEG, QEEG and multimodal ERP examinations;
  10. Publication of scientific papers.