Edward Ziff

Biosketch / Results /

Edward Ziff, Ph.D.

Professor; Graduate Student Advisor
Department of Biochemistry and Molecular Pharmacology

Contact Info

Address
540 First Avenue
Department of Biochemistry Floor 5 Room 1 and 2
Skirball Institute
New York, NY 10016

212-263-5774, 212-263-5939
212-263-8214
Edward.Ziff@nyumc.org


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Education

— Princeton University, Graduate Education
1969-1973 — Princeton University, PostDoctoral Training
1970-1973 — NIH Postdoctoral Fellowship at the MRC, Cambridge, UK with Dr. F. Sanger, PostDoctoral Training

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Research Summary

Our lab studies the molecular mechanisms which regulate synaptic transmission at excitatory synapses. We focus on two ion channels, the AMPA and the NMDA type glutamate receptors. These receptors are multisubunited pores that admit cations into the postsynaptic cell when stimulated by glutamate. AMPA receptors function in fast excitatory transmission while NMDA receptors function in altering synaptic architecture and transmission strength. Both receptor types are composed of integral membrane protein subunits that project domains outside the cell and into the cytoplasm. The cytoplasmic domains associate with binding proteins that serve as attachment sites to the cytoskeleton or to regulatory proteins (such as kinase or phosphatases) that modify receptor activity. We have cloned proteins which associate with the cytoplasmic tail of the GluR2 AMPA type glutamate receptor subunit and are studying the role of these binding factors in receptor control. One protein that binds to GluR2 is the chaperone, NSF. A second protein is AMPA Receptor Binding Protein (ABP). ABP may form a cytoplasmic scaffold that binds receptors at the synapse. We are testing a model that NSF regulates the attachment of GluR2 to ABP and other cytoplasmic factors. We are studying the role of the NMDA receptor in the control of the AMPA receptor. Our goal is to obtain a molecular view of changes in synaptic signaling induced by neuron activity.

Research Interests

Molecular Mechanisms of Synaptic Regulation

Research Keywords

synapse, ion channel, glutamate receptor, neurobiology

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Animal Models for Depression Associated with HIV-1 Infection
Barreto, Isabella Cristina Gomes; Viegas, Patricia; Ziff, Edward B; Konkiewitz, Elisabete Castelon
2014 Mar;9(2):195-208, Journal of neuroimmune pharmacology
— id: 882942, year: 2014, vol: 9, page: 195, stat: Journal Article,

Trafficking of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA) receptor subunit GluA2 from the endoplasmic reticulum is stimulated by a complex containing Ca2+/calmodulin-activated kinase II (CaMKII) and PICK1 protein and by release of Ca2+ from internal stores
Lu, Wei; Khatri, Latika; Ziff, Edward B
2014 Jul;289(27):19218-19230, Journal of biological chemistry
— id: 1186542, year: 2014, vol: 289, page: 19218, stat: Journal Article,

Involvement of nucleus accumbens AMPA receptor trafficking in augmentation of D- amphetamine reward in food-restricted rats
Peng, Xing-Xiang; Cabeza de Vaca, Soledad; Ziff, Edward B; Carr, Kenneth D
2014 Feb;:538-544, Psychopharmacology
— id: 900402, year: 2014, vol: , page: 538, stat: Journal Article,

cGMP-dependent protein kinase type II knockout mice exhibit working memory impairments, decreased repetitive behavior, and increased anxiety-like traits
Wincott, Charlotte M; Abera, Sinedu; Vunck, Sarah A; Choi, Yoon; Titcombe, Roseann F; Antoine, Shannon O; Tukey, David S; Devito, Loren M; Hofmann, Franz; Hoeffer, Charles A; Ziff, Edward B
2014 Apr;:610-615, Neurobiology of learning & memory
— id: 933362, year: 2014, vol: , page: 610, stat: Journal Article,

Sterile brain abscess due to juvenile xanthogranuloma: DWI characteristics
Bushnell, Philip J.; Strupp, Barbara J.; Rice, Margaret E.; Avshalumov, Marat V.; Patel, Jyoti C.; Hrabetova, Sabina; Nicholson, Charles; Jordan, Bryen A.; Fernholz, Brian D.; Neubert, Thomas A.; Ziff, Edward B.; Faltz, Lawrence L; Morley, John N; Flink, Ellen; Dameron, Peg DeHont; Al-Ibrahim, Mohamed S.; Gross, Joyce Y.; Albertson, Donna G; Rose, Ann M; Villeneuve, Anne M; Batuman, Fatma; Bean-Mayberry, Bevanne; Goldzweig, Caroline; Huang, Christine; Miake-Lye, Isomi M; Washington, Donna L; Yano, Elizabeth M; Zephyrin, Laurie C; Shekelle, Paul G; Walton, Kerry D.; Llinas, Rodolfo R.; Kwak, Ellie S; Marrero, Daniel E; Pfannl, Rolf; Erbay, Sami H
2013 Jul;23(3):437-440, Journal of neuroimaging
— id: 1012782, year: 2013, vol: 23, page: 437, stat: Journal Article,

Human immunodeficiency virus-associated depression: contributions of immuno-inflammatory, monoaminergic, neurodegenerative, and neurotrophic pathways
Del Guerra, F B; Fonseca, J L I; Figueiredo, V M; Ziff, E B; Konkiewitz, E Castelon
2013 Jul;:314-327, Journal of neurovirology
— id: 489242, year: 2013, vol: , page: 314, stat: Journal Article,

Calcium-permeable AMPA receptors in the nucleus accumbens regulate depression-like behaviors in the chronic neuropathic pain state
Goffer, Yossef; Xu, Duo; Eberle, Sarah E; D'amour, James; Lee, Michelle; Tukey, David; Froemke, Robert C; Ziff, Edward B; Wang, Jing
2013 Nov;33(48):19034-19044, Journal of neuroscience
— id: 666292, year: 2013, vol: 33, page: 19034, stat: Journal Article,

The type II cGMP dependent protein kinase regulates GluA1 levels at the plasma membrane of developing cerebellar granule cells
Incontro, Salvatore; Ciruela, Francisco; Ziff, Edward; Hofmann, Franz; Sanchez-Prieto, Jose; Torres, Magdalena
2013 Aug;1833(8):1820-1831, Biochimica & biophysica acta
— id: 368222, year: 2013, vol: 1833, page: 1820, stat: Journal Article,

Sucrose ingestion induces rapid AMPA receptor trafficking
Tukey, David S; Ferreira, Jainne M; Antoine, Shannon O; D'amour, James A; Ninan, Ipe; Cabeza de Vaca, Soledad; Incontro, Salvatore; Wincott, Charlotte; Horwitz, Julian K; Hartner, Diana T; Guarini, Carlo B; Khatri, Latika; Goffer, Yossef; Xu, Duo; Titcombe, Roseann F; Khatri, Megna; Marzan, Dave S; Mahajan, Shahana S; Wang, Jing; Froemke, Robert C; Carr, Kenneth D; Aoki, Chiye; Ziff, Edward B
2013 Apr;33(14):6123-6132, Journal of neuroscience
— id: 271462, year: 2013, vol: 33, page: 6123, stat: Journal Article,

Differential effects of natural rewards and pain on vesicular glutamate transporter expression in the nucleus accumbens
Tukey, David S; Lee, Michelle; Xu, Duo; Eberle, Sarah E; Goffer, Yossef; Manders, Toby R; Ziff, Edward B; Wang, Jing
2013 ;6(1):32-32, Molecular brain
— id: 438882, year: 2013, vol: 6, page: 32, stat: Journal Article,

Ca2+-permeable AMPA (alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid) Receptors and Dopamine D1 Receptors Regulate GluA1 Trafficking in Striatal Neurons
Tukey, David S; Ziff, Edward B
2013 Dec;288(49):35297-35306, Journal of biological chemistry
— id: 680972, year: 2013, vol: 288, page: 35297, stat: Journal Article,

Spatial memory deficits and motor coordination facilitation in cGMP-dependent protein kinase type II-deficient mice
Wincott, Charlotte M; Kim, Seonil; Titcombe, Roseann F; Tukey, David S; Girma, Hiwot K; Pick, Joseph E; Devito, Loren M; Hofmann, Franz; Hoeffer, Charles; Ziff, Edward B
2013 Jan;99:32-37, Neurobiology of learning & memory
— id: 213272, year: 2013, vol: 99, page: 32, stat: Journal Article,

Metophyma: Case Report and Review of a Rare Phyma Variant
Bushnell, Philip J.; Strupp, Barbara J.; Rice, Margaret E.; Avshalumov, Marat V.; Patel, Jyoti C.; Hrabetova, Sabina; Nicholson, Charles; Jordan, Bryen A.; Fernholz, Brian D.; Neubert, Thomas A.; Ziff, Edward B.; Faltz, Lawrence L; Morley, John N; Flink, Ellen; Dameron, Peg DeHont; Al-Ibrahim, Mohamed S.; Gross, Joyce Y.; Albertson, Donna G; Rose, Ann M; Villeneuve, Anne M; Chan, Joanna L; Soliman, Sameer; Miner, Andrew G; Hughes, Stephen M; Cockerell, Clay J; Perone, Jennifer B
2011 Jun;:929; author reply 930-929; author reply 931, Dermatologic surgery
— id: 1003402, year: 2011, vol: , page: 929; author reply 930, stat: Journal Article,

Intercellular cancer collisions generate an ejected crystal comet tail effect with fractal interface embryoid body reassembly transformation
Bushnell, Philip J.; Strupp, Barbara J.; Rice, Margaret E.; Avshalumov, Marat V.; Patel, Jyoti C.; Hrabetova, Sabina; Nicholson, Charles; Jordan, Bryen A.; Fernholz, Brian D.; Neubert, Thomas A.; Ziff, Edward B.; Faltz, Lawrence L; Morley, John N; Flink, Ellen; Dameron, Peg DeHont; Al-Ibrahim, Mohamed S.; Gross, Joyce Y.; Mobasheri, Ali; Barrett-Jolley, Richard; Shakibaei, Mehdi; Canessa, Cecilia M.; Martin-Vasallo, Pablo; Mobasheri, Ali; Barrett-Jolley, Richard; Carter, Stuart D.; Martin-Vasallo, Pablo; Schulze-Tanzil, Gundula; Shakibaei, Mehdi; Albertson, Donna G; Rose, Ann M; Villeneuve, Anne M; Diaz, Jairo A; Murillo, Mauricio F; Barrero, Alvaro
2011 Aug;3:143-155, Cancer management & research
— id: 995532, year: 2011, vol: 3, page: 143, stat: Journal Article,

Serotonin mediates cross-modal reorganization of cortical circuits
Jitsuki, Susumu; Takemoto, Kiwamu; Kawasaki, Taisuke; Tada, Hirobumi; Takahashi, Aoi; Becamel, Carine; Sano, Akane; Yuzaki, Michisuke; Zukin, R Suzanne; Ziff, Edward B; Kessels, Helmut W; Takahashi, Takuya
2011 Feb;69(4):780-792, Neuron
— id: 330542, year: 2011, vol: 69, page: 780, stat: Journal Article,

Exposure of neurons to excitotoxic levels of glutamate induces cleavage of the RNA editing enzyme, adenosine deaminase acting on RNA 2, and loss of GLUR2 editing
Mahajan, S S; Thai, K H; Chen, K; Ziff, E
2011 Aug 25;189:305-315, Neuroscience
— id: 135556, year: 2011, vol: 189, page: 305, stat: Journal Article,

Effects of food restriction and sucrose intake on synaptic delivery of AMPA receptors in nucleus accumbens
Peng XX; Ziff EB; Carr KD
2011 Oct;65(10):1024-1031, Synapse
— id: 134092, year: 2011, vol: 65, page: 1024, stat: Journal Article,

Synaptic Autoregulation by Metalloproteases and {gamma}-Secretase
Restituito, Sophie; Khatri, Latika; Ninan, Ipe; Mathews, Paul M; Liu, Xin; Weinberg, Richard J; Ziff, Edward B
2011 Aug 24;31(34):12083-12093, Journal of neuroscience
— id: 136951, year: 2011, vol: 31, page: 12083, stat: Journal Article,

A single subanesthetic dose of ketamine relieves depression-like behaviors induced by neuropathic pain in rats
Wang, Jing; Goffer, Yossef; Xu, Duo; Tukey, David S; Shamir, D B; Eberle, Sarah E; Zou, Anthony H; Blanck, Thomas J J; Ziff, Edward B
2011 Oct;115(4):812-821, Anesthesiology
— id: 139733, year: 2011, vol: 115, page: 812, stat: Journal Article,

Ephrin-A5 and EphA5 Interaction Induces Synaptogenesis during Early Hippocampal Development. L
Akaneya, Yukio; Sohya, Kazuhiro; Kitamura, Akihiko; Kimura, Fumitaka; Washburn, Chris; Zhou, Renping; Ninan, Ipe; Tsumoto, Tadaharu; Ziff, Edward B
2010 ;5(8):e12486-e12486, PLoS one
— id: 112206, year: 2010, vol: 5, page: e12486, stat: Journal Article,

AMPA receptor subunit GluR1 downstream of D-1 dopamine receptor stimulation in nucleus accumbens shell mediates increased drug reward magnitude in food-restricted rats
Carr, K D; Chau, L S; Cabeza de Vaca, S; Gustafson, K; Stouffer, M; Tukey, D S; Restituito, S; Ziff, E B
2010 Feb 17;165(4):1074-1086, Neuroscience
— id: 106493, year: 2010, vol: 165, page: 1074, stat: Journal Article,

Regulation of synaptic structure and function by palmitoylated AMPA receptor binding protein
Misra, Charu; Restituito, Sophie; Ferreira, Jainne; Rameau, Gerald A; Fu, Jie; Ziff, Edward B
2010 Apr;43(4):341-352, Molecular & cellular neurosciences
— id: 108427, year: 2010, vol: 43, page: 341, stat: Journal Article,

How the mind works: Revelations (Jean-Pierre Changeux)
Rosenfield, I; Ziff, E
2008 JUN 26 ;55(11):62-65, New York review of books
— id: 86956, year: 2008, vol: 55, page: 62, stat: Journal Article,

A role for cGMP-dependent protein kinase II in AMPA receptor trafficking and synaptic plasticity
Serulle, Yafell; Arancio, Ottavio; Ziff, Edward B
2008 Jul-Aug;2(4):230-232, Channels (Austin, Tex.)
— id: 93359, year: 2008, vol: 2, page: 230, stat: Journal Article,

Stable synaptic retention of serine-880-phosphorylated GluR2 in hippocampal neurons
States, Bradley A; Khatri, Latika; Ziff, Edward B
2008 Jun;38(2):189-202, Molecular & cellular neurosciences
— id: 83101, year: 2008, vol: 38, page: 189, stat: Journal Article,

Molecular determinants of AMPA receptor subunit assembly
Greger, Ingo H; Ziff, Edward B; Penn, Andrew C
2007 Aug;30(8):407-416, Trends in neurosciences
— id: 94126, year: 2007, vol: 30, page: 407, stat: Journal Article,

Activity-dependent AIDA-1 nuclear signaling regulates nucleolar numbers and protein synthesis in neurons
Jordan, Bryen A; Fernholz, Brian D; Khatri, Latika; Ziff, Edward B
2007 Apr;10(4):427-435, Nature neuroscience
— id: 71907, year: 2007, vol: 10, page: 427, stat: Journal Article,

Novel toxicity of the unedited GluR2 AMPA receptor subunit dependent on surface trafficking and increased Ca2+-permeability
Mahajan, S S; Ziff, E B
2007 Jul;35(3):470-481, Molecular & cellular neurosciences
— id: 73862, year: 2007, vol: 35, page: 470, stat: Journal Article,

Biphasic coupling of neuronal nitric oxide synthase phosphorylation to the NMDA receptor regulates AMPA receptor trafficking and neuronal cell death
Rameau, Gerald A; Tukey, David S; Garcin-Hosfield, Elsa D; Titcombe, Roseann F; Misra, Charu; Khatri, Latika; Getzoff, Elizabeth D; Ziff, Edward B
2007 Mar 28;27(13):3445-3455, Journal of neuroscience
— id: 71906, year: 2007, vol: 27, page: 3445, stat: Journal Article,

A GluR1-cGKII interaction regulates AMPA receptor trafficking
Serulle, Yafell; Zhang, Shuang; Ninan, Ipe; Puzzo, Daniela; McCarthy, Maria; Khatri, Latika; Arancio, Ottavio; Ziff, Edward B
2007 Nov 21;56(4):670-688, Neuron
— id: 75310, year: 2007, vol: 56, page: 670, stat: Journal Article,

Synaptic anchorage of AMPA receptors by cadherins through neural plakophilin-related arm protein AMPA receptor-binding protein complexes
Silverman, Joshua B; Restituito, Sophie; Lu, Wei; Lee-Edwards, Laveria; Khatri, Latika; Ziff, Edward B
2007 Aug 8;27(32):8505-8516, Journal of neuroscience
— id: 73706, year: 2007, vol: 27, page: 8505, stat: Journal Article,

TARPs and the AMPA receptor trafficking paradox
Ziff, Edward B
2007 Mar 1;53(5):627-633, Neuron
— id: 71421, year: 2007, vol: 53, page: 627, stat: Journal Article,

Developmentally regulated, combinatorial RNA processing modulates AMPA receptor biogenesis
Greger, Ingo H; Akamine, Pearl; Khatri, Latika; Ziff, Edward B
2006 Jul 6;51(1):85-97, Neuron
— id: 71908, year: 2006, vol: 51, page: 85, stat: Journal Article,

New tricks for an old dog: proteomics of the PSD
Jordan, BA; Fernholz, BD; Neubert, TA; Ziff, EB
The dynamic synapse : molecular methods in ionotropic receptor biology Boca Raton, FL : CRC/Taylor & Francis, 2006,
— id: 972102, year: 2006, vol: , page: ?, stat: Chapter,

Getting to synaptic complexes through systems biology
Jordan, Bryen A; Ziff, Edward B
2006 ;7(4):214-214, Genome biology
— id: 65253, year: 2006, vol: 7, page: 214, stat: Journal Article,

Membrane localization of membrane type 5 matrix metalloproteinase by AMPA receptor binding protein and cleavage of cadherins
Monea, Sara; Jordan, Bryen A; Srivastava, Sapna; DeSouza, Sunita; Ziff, Edward B
2006 Feb 22;26(8):2300-2312, Journal of neuroscience
— id: 63742, year: 2006, vol: 26, page: 2300, stat: Journal Article,

Identification of transcriptional regulators of neuropeptide FF gene expression
Nystedt, Johanna M; Brandt, Annika; Vilim, Ferdinand S; Ziff, Edward B; Panula, Pertti
2006 May;27(5):1020-1035, Peptides
— id: 71909, year: 2006, vol: 27, page: 1020, stat: Journal Article,

Methods for uncovering the mechanisms of AMPA receptor trafficking
Restituito, Sophie ; Ziff, Edward B
The dynamic synapse : molecular methods in ionotropic receptor biology Boca Raton, FL : CRC/Taylor & Francis, 2006,
— id: 972092, year: 2006, vol: , page: ?, stat: Chapter,

PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking
Lu, Wei; Ziff, Edward B
2005 Aug 4;47(3):407-421, Neuron
— id: 71911, year: 2005, vol: 47, page: 407, stat: Journal Article,

EphB2 gets a GRIP on the dendritic arbor
Misra, Charu; Ziff, Edward B
2005 Jul;8(7):848-850, Nature neuroscience
— id: 71910, year: 2005, vol: 8, page: 848, stat: Journal Article,

Identification and verification of novel rodent postsynaptic density proteins
Jordan, Bryen A; Fernholz, Brian D; Boussac, Muriel; Xu, Chongfeng; Grigorean, Gabriela; Ziff, Edward B; Neubert, Thomas A
2004 Sep;3(9):857-871, Molecular & cellular proteomics
— id: 48196, year: 2004, vol: 3, page: 857, stat: Journal Article,

Bidirectional regulation of neuronal nitric-oxide synthase phosphorylation at serine 847 by the N-methyl-D-aspartate receptor
Rameau, Gerald A; Chiu, Ling-Yu; Ziff, Edward B
2004 Apr 2;279(14):14307-14314, Journal of biological chemistry
— id: 44853, year: 2004, vol: 279, page: 14307, stat: Journal Article,

Protein interactions and the control of AMPA receptor trafficking
Ziff, EB; Khatri, L; Kong, X; Greger, I
2004 FEB ;88(5):5-5, Journal of neurochemistry
— id: 42487, year: 2004, vol: 88, page: 5, stat: Journal Article,

Intracellular membrane targeting and suppression of Ser880 phosphorylation of glutamate receptor 2 by the linker I-set II domain of AMPA receptor-binding protein
Fu, Jie; deSouza, Sunita; Ziff, Edward B
2003 Aug 20;23(20):7592-7601, Journal of neuroscience
— id: 39103, year: 2003, vol: 23, page: 7592, stat: Journal Article,

AMPA receptor assembly determined by Q/R editing
Greger, I. H.; Khatri, L.; Kong, X.; Ziff, E. B.
2003 ;2003:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92627, year: 2003, vol: 2003, page: ?, stat: Journal Article,

AMPA receptor tetramerization is mediated by Q/R editing
Greger, Ingo H; Khatri, Latika; Kong, Xiangpeng; Ziff, Edward B
2003 Nov 13;40(4):763-774, Neuron
— id: 44855, year: 2003, vol: 40, page: 763, stat: Journal Article,

Dream is a potential transcriptional regulator of neuropeptide FF gene expression
Nystedt, J. M.; Vilim, F. S.; Ziff, E. B.; Panula, P.
2003 ;2003:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92628, year: 2003, vol: 2003, page: ?, stat: Journal Article,

NMDA receptor regulation of nNOS phosphorylation and induction of neuron death
Rameau, Gerald A; Chiu, Ling-Yu; Ziff, Edward B
2003 Dec;24(8):1123-1133, Neurobiology of aging
— id: 44854, year: 2003, vol: 24, page: 1123, stat: Journal Article,

Protein interactions and the trafficking of AMPA receptors
Ziff, EB; Greger, I; Fu, J; deSouza, S; States, B; Lu, W; Khatri, L; Lee-Edwards, L
2003 DEC ;87(1):35-35, Journal of neurochemistry
— id: 42522, year: 2003, vol: 87, page: 35, stat: Journal Article,

Receptor trafficking and the plasticity of excitatory synapses
Barry, Michael F; Ziff, Edward B
2002 Jun;12(3):279-286, Current opinion in neurobiology
— id: 35235, year: 2002, vol: 12, page: 279, stat: Journal Article,

Ca2+-dependent formation of a dynamin-synaptophysin complex: potential role in synaptic vesicle endocytosis
Daly, Christopher; Ziff, Edward B
2002 Mar 15;277(11):9010-9015, Journal of biological chemistry
— id: 35238, year: 2002, vol: 277, page: 9010, stat: Journal Article,

Differential palmitoylation directs the AMPA receptor-binding protein ABP to spines or to intracellular clusters
DeSouza, Sunita; Fu, Jie; States, Bradley A; Ziff, Edward B
2002 May 1;22(9):3493-3503, Journal of neuroscience
— id: 35236, year: 2002, vol: 22, page: 3493, stat: Journal Article,

AMPA receptors do the electric slide
deSouza, Sunita; Ziff, Edward B
2002 Oct 29;2002(156):pe45-pe45, Science's STKE
— id: 35231, year: 2002, vol: 2002, page: pe45, stat: Journal Article,

INTRACELLULAR MEMBRANE TARGETING AND SUPPRESSION OF SER880 PHOSPHORYLATION OF GluR2 BY THE Li - SII SUBDOMAIN OF ABP
Fu, J.; DeSouza, S.; Ma, X.; Ziff, E. B.
2002 ;2002:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92629, year: 2002, vol: 2002, page: ?, stat: Journal Article,

Association of the AMPA receptor-related postsynaptic density proteins GRIP and ABP with subsets of glutamate-sensitive neurons in the rat retina
Gabriel, Robert; de Souza, Sunita; Ziff, Edward B; Witkovsky, Paul
2002 Jul 22;449(2):129-140, Journal of comparative neurology
— id: 35233, year: 2002, vol: 449, page: 129, stat: Journal Article,

RNA EDITING AT ARG607 CONTROLS AMPA RECEPTOR EXIT FROM THE ENDOPLASMIC RETICULUM
Greger, I. H.; Khatri, L.; Hong, K.; Ziff, E. B.
2002 ;2002:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92632, year: 2002, vol: 2002, page: ?, stat: Journal Article,

RNA editing at arg607 controls AMPA receptor exit from the endoplasmic reticulum
Greger, Ingo H; Khatri, Latika; Ziff, Edward B
2002 May 30;34(5):759-772, Neuron
— id: 35234, year: 2002, vol: 34, page: 759, stat: Journal Article,

NSF ATPase and alpha-/beta-SNAPs disassemble the AMPA receptor-PICK1 complex
Hanley, Jonathan G; Khatri, Latika; Hanson, Phyllis I; Ziff, Edward B
2002 Mar 28;34(1):53-67, Neuron
— id: 35237, year: 2002, vol: 34, page: 53, stat: Journal Article,

Analysis of human neuropeptide FF gene expression
Nystedt, Johanna M; Brandt, Annika M; Mandelin, Jami; Vilim, Ferdinand S; Ziff, Edward B; Panula, Pertti
2002 Sep;82(6):1330-1342, Journal of neurochemistry
— id: 35232, year: 2002, vol: 82, page: 1330, stat: Journal Article,

NMDA RECEPTORS ACTIVATION REGULATE NOS PHOSPHORYLATION AND APOPTOTIC NEURON DEATH. G.A. RAMEAU*, P. WITKOVSKY, L. CHIU AND E. B. ZIFF. HHMI, DEPT. OF BIOCHEMISTRY, NYU SCH. OF MED., NEW YORK, NY 10016
Rameau, G. A.; Witkovsky, P.; Chiu, L.; Ziff, E. B.
2002 ;2002:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92630, year: 2002, vol: 2002, page: ?, stat: Journal Article,

DELETION OF THE JUXTAMEMBRANE 10 AMINO ACIDS OF THE GluR2 C - TERMINUS INCREASES INTERNALIZATION THE EXOGENOUS RECEPTOR IN CULTURED HIPPOCAMPAL NEURONS
States, B. A.; Khatri, L.; Ziff, E. B.
2002 ;2002:?-?, Society for Neuroscience Abstract Viewer & Itinerary Planner
— id: 92631, year: 2002, vol: 2002, page: ?, stat: Journal Article,

Characterization of the phenotype of neuropeptide FF knockout mice
Brandt, A. M.; Westerlund, J. M.; Pietila, P.; Vilim, F. S.; Ziff, E. B.; Panula, P.
2001 ;27(1):70-70, Abstracts (Society for Neuroscience)
— id: 92634, year: 2001, vol: 27, page: 70, stat: Journal Article,

Differential Cellular and Subcellular Localization of AMPA Receptor-Binding Protein and Glutamate Receptor-Interacting Protein
Burette A; Khatri L; Wyszynski M; Sheng M; Ziff EB; Weinberg RJ
2001 Jan 15;21(2):495-503, Journal of neuroscience
— id: 17519, year: 2001, vol: 21, page: 495, stat: Journal Article,

Association of AMPA receptor sub-units GluR2/3 with two AMPA receptor-specific proteins, GRIP and ABP, in rat retinal neurons
Gabriel, R; Witkovsky, P; Ziff, E; deSouza, S
2001 MAR 15 ;42(4):S728-S728, Investigative ophthalmology & visual science. IOVS
— id: 54988, year: 2001, vol: 42, page: S728, stat: Journal Article,

The majority of the GluR2 AMPA-receptor subunit stably resides in the endoplasmic reticulum
Greger, I. H.; Ziff, E. B.
2001 ;27(1):77-77, Abstracts (Society for Neuroscience)
— id: 92635, year: 2001, vol: 27, page: 77, stat: Journal Article,

Regulation of AMPA receptor GLuR2 subunit-PDZ protein interactions by NSF and alpha/beta-SNAPs
Hanley, J. G.; Khatri, L.; Hanson, P. I.; Ziff, E. B.
2001 ;27(1):403-403, Abstracts (Society for Neuroscience)
— id: 92633, year: 2001, vol: 27, page: 403, stat: Journal Article,

Transcription factors in melanocyte development: distinct roles for Pax-3 and Mitf
Hornyak TJ; Hayes DJ; Chiu L; Ziff EB
2001 Mar;101(1-2):47-59, Mechanisms of development
— id: 17518, year: 2001, vol: 101, page: 47, stat: Journal Article,

Transcriptional repression activity and induction of RPE neural differentiation revealed by expression of Mash-1 transcription factor in pigment cell precursors in transgenic mice
Hornyak, T; Gavin, J; Jiao, Z; Gawel, J; Ziff, E
2001 AUG ;117(2):508-508, Journal of investigative dermatology
— id: 54903, year: 2001, vol: 117, page: 508, stat: Journal Article,

PICK1 targets activated protein kinase Calpha to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2
Perez JL; Khatri L; Chang C; Srivastava S; Osten P; Ziff EB
2001 Aug 1;21(15):5417-5428, Journal of neuroscience
— id: 26724, year: 2001, vol: 21, page: 5417, stat: Journal Article,

Synaptophysin regulates clathrin-independent endocytosis of synaptic vesicles
Daly C; Sugimori M; Moreira JE; Ziff EB; Llinas R
2000 May 23;97(11):6120-6125, Proceedings of the National Academy of Sciences of the United States of America
— id: 9869, year: 2000, vol: 97, page: 6120, stat: Journal Article,

ABP splice variants: differential co-localization with AMPA receptors in hippocampal neurons
de Souza, S.; Osten, P.; Khatri, L.; Ziff, E. B.
2000 ;26(1-2):?-?, Abstracts (Society for Neuroscience)
— id: 92636, year: 2000, vol: 26, page: ?, stat: Journal Article,

Microphthalmia and loss of coat pigmentation from transgenic expression of a neurogenic factor in pigment cell precursors [In Process Citation]
Hornyak TJ; Gavin J; Jiao Z; Ziff EB
2000 Aug;115(2):332-332, Journal of investigative dermatology
— id: 11537, year: 2000, vol: 115, page: 332, stat: Journal Article,

Cell-density-dependent regulation of expression and glycosylation of dopachrome tautomerase/tyrosinase-related protein-2
Hornyak TJ; Hayes DJ; Ziff EB
2000 Jul;115(1):106-112, Journal of investigative dermatology
— id: 11610, year: 2000, vol: 115, page: 106, stat: Journal Article,

Synaptophysin regulates clathrin-independent endocytosis of synaptic vesicles
Llinas, R.; Daly, C.; Sugimori, M.; Moreira, J. E.; Ziff, E. B.
2000 ;26(1-2):?-?, Abstracts (Society for Neuroscience)
— id: 92313, year: 2000, vol: 26, page: ?, stat: Journal Article,

Mutagenesis reveals a role for ABP/GRIP binding to GluR2 in synaptic surface accumulation of the AMPA receptor
Osten P; Khatri L; Perez JL; Kohr G; Giese G; Daly C; Schulz TW; Wensky A; Lee LM; Ziff EB
2000 Aug;27(2):313-325, Neuron
— id: 17521, year: 2000, vol: 27, page: 313, stat: Journal Article,

Role of NMDA receptor functional domains in excitatory cell death
Rameau GA; Akaneya Y; Chiu L; Ziff EB
2000 Sep;39(12):2255-2266, Neuropharmacology
— id: 17522, year: 2000, vol: 39, page: 2255, stat: Journal Article,

NMDA-induced apoptotic cell death mediated by activated caspase-3
Rameau, G. A.; Chiu, L.; Ziff, E. B.
2000 ;26(1-2):?-?, Abstracts (Society for Neuroscience)
— id: 92638, year: 2000, vol: 26, page: ?, stat: Journal Article,

Novel interactions with AMPA receptor binding protein (ABP)
Silverman, J. B.; Bloomfield, S.; Ziff, E. B.
2000 ;26(1-2):?-?, Abstracts (Society for Neuroscience)
— id: 92637, year: 2000, vol: 26, page: ?, stat: Journal Article,

Consistent and selective expression of the discoidin domain receptor-1 tyrosine kinase in human brain tumors
Weiner HL; Huang H; Zagzag D; Boyce H; Lichtenbaum R; Ziff EB
2000 Dec;47(6):1400-1409, Neurosurgery
— id: 17520, year: 2000, vol: 47, page: 1400, stat: Journal Article,

KCl induces an activity-dependent expression of NMDA receptors in early development of rat hippocampal neurons in culture
Akaneya, Y.; Ziff, E. B.
1999 ;25(1-2):203-203, Abstracts (Society for Neuroscience)
— id: 92643, year: 1999, vol: 25, page: 203, stat: Journal Article,

Activity-dependent regulation of AMPA receptors and AMPA receptor binding proteins in the adult mouse olfactory bulb
Baker, H.; Liu, N.; Berlin, R. A.; DeSouza, S.; Ziff, E. B.
1999 ;25(1-2):128-128, Abstracts (Society for Neuroscience)
— id: 92641, year: 1999, vol: 25, page: 128, stat: Journal Article,

FGF-2 potentiates Ca(2+)-dependent inactivation of NMDA receptor currents in hippocampal neurons
Boxer AL; Moreno H; Rudy B; Ziff EB
1999 Dec;82(6):3367-3377, Journal of neurophysiology
— id: 11900, year: 1999, vol: 82, page: 3367, stat: Journal Article,

Cloning and functional characterization of the 5' flanking region of neuropeptide FF promoter
Brandt, A.; Westerlund, J.; Vikstrom, S.; Vilim, F. S.; States, B.; Ziff, E.; Panula, P.
1999 ;25(1-2):2225-2225, Abstracts (Society for Neuroscience)
— id: 92640, year: 1999, vol: 25, page: 2225, stat: Journal Article,

ABP splice variants: Differential co-localization with AMPA receptors in hippocampal neurons
deSouza, S.; Osten, P.; Khatri, L.; Rameau, G.; Ziff, E. B.
1999 ;25(1-2):732-732, Abstracts (Society for Neuroscience)
— id: 92639, year: 1999, vol: 25, page: 732, stat: Journal Article,

Mxi1 is a repressor of the c-Myc promoter and reverses activation by USF
Lee TC; Ziff EB
1999 Jan 8;274(2):595-606, Journal of biological chemistry
— id: 7384, year: 1999, vol: 274, page: 595, stat: Journal Article,

AMPA receptor forms a biochemically functional complex with NSF and alpha- and beta-SNAPs
Osten P; Ziff EB
1999 Apr 30;868:558-560, Annals of the New York Academy of Sciences
— id: 56457, year: 1999, vol: 868, page: 558, stat: Journal Article,

The role of the GluR2 C-terminus in trafficking of the AMPA receptor
Osten, P.; Khatri, L.; Perez, J. L.; Ziff, E. B.
1999 ;25(1-2):25-25, Abstracts (Society for Neuroscience)
— id: 92642, year: 1999, vol: 25, page: 25, stat: Journal Article,

ABP: a novel AMPA receptor binding protein
Srivastava S; Ziff EB
1999 Apr 30;868:561-564, Annals of the New York Academy of Sciences
— id: 56458, year: 1999, vol: 868, page: 561, stat: Journal Article,

Gene for pain modulatory neuropeptide NPFF: induction in spinal cord by noxious stimuli
Vilim FS; Aarnisalo AA; Nieminen ML; Lintunen M; Karlstedt K; Kontinen VK; Kalso E; States B; Panula P; Ziff E
1999 May;55(5):804-811, Molecular pharmacology
— id: 56427, year: 1999, vol: 55, page: 804, stat: Journal Article,

Consistent and selective expression of the DDR1 tyrosine kinase in high grade human brain tumors
Weiner HL; Huang HY; Zagzag D; Ziff EB
1999 ;1:345-345, Neuro-oncology
— id: 34023, year: 1999, vol: 1, page: 345, stat: Journal Article,

Recent excitement in the ionotropic glutamate receptor field
Ziff EB
1999 Apr 30;868:465-473, Annals of the New York Academy of Sciences
— id: 56456, year: 1999, vol: 868, page: 465, stat: Journal Article,

Expression of glutamate receptor-binding PDZ proteins from adenovirus vectors in the CNS in vitro and in vivo
Akaneya, Y.; States, B.; Khatri, L.; Schneider, R.; Ziff, E. B.
1998 ;24(1-2):571-571, Abstracts (Society for Neuroscience)
— id: 92645, year: 1998, vol: 24, page: 571, stat: Journal Article,

AP-1, CREB and CBP transcription factors differentially regulate the tyrosine hydroxylase gene
Ghee M; Baker H; Miller JC; Ziff EB
1998 Mar 30;55(1):101-114, Brain research. Molecular brain research
— id: 57153, year: 1998, vol: 55, page: 101, stat: Journal Article,

Role of MITF in melanocyte development: A transgenic analysis
Hornyak, TJ; Harada, FT; Ziff, EB
1998 APR ;110(4):477-477, Journal of investigative dermatology
— id: 53520, year: 1998, vol: 110, page: 477, stat: Journal Article,

Altered expression of helix-loop-helix transcriptional regulators and cyclin D1 in Wnt-1-transformed PC12 cells
Issack PS; Ziff EB
1998 Oct;9(10):837-845, Cell growth & differentiation
— id: 57040, year: 1998, vol: 9, page: 837, stat: Journal Article,

Genetic elements regulating HES-1 induction in Wnt-1-transformed PC12 cells
Issack PS; Ziff EB
1998 Oct;9(10):827-836, Cell growth & differentiation
— id: 57172, year: 1998, vol: 9, page: 827, stat: Journal Article,

The AMPA receptor GluR2 C terminus can mediate a reversible, ATP-dependent interaction with NSF and alpha- and beta-SNAPs
Osten P; Srivastava S; Inman GJ; Vilim FS; Khatri L; Lee LM; States BA; Einheber S; Milner TA; Hanson PI; Ziff EB
1998 Jul;21(1):99-110, Neuron
— id: 7726, year: 1998, vol: 21, page: 99, stat: Journal Article,

Functional characterization of the AMPA receptor-NSF-SNAP complex
Osten, P.; Khatri, L.; States, B. A.; Barry, M. F.; Ziff, E. B.
1998 ;24(1-2):842-842, Abstracts (Society for Neuroscience)
— id: 92644, year: 1998, vol: 24, page: 842, stat: Journal Article,

Identification of NMDA receptor dominant mutations and study of receptor apoptotic function
Rameau, G.; Akaneya, Y.; Ziff, E. B.
1998 ;24(1-2):279-279, Abstracts (Society for Neuroscience)
— id: 92646, year: 1998, vol: 24, page: 279, stat: Journal Article,

Novel anchorage of GluR2/3 to the postsynaptic density by the AMPA receptor-binding protein ABP
Srivastava S; Osten P; Vilim FS; Khatri L; Inman G; States B; Daly C; DeSouza S; Abagyan R; Valtschanoff JG; Weinberg RJ; Ziff EB
1998 Sep;21(3):581-591, Neuron
— id: 7975, year: 1998, vol: 21, page: 581, stat: Journal Article,

Expression of NPFF mRNA in carrageenan inflammation in the spinal cord of rat
Aarnisalo, A. A.; Nieminen, M.; Kontinen, V. K.; Vilim, S.; Kalso, E.; Ziff, E.; Panula, P.
1997 ;23(1-2):1806-1806, Abstracts (Society for Neuroscience)
— id: 92648, year: 1997, vol: 23, page: 1806, stat: Journal Article,

Post-transcriptional regulation of synaptic vesicle protein expression and the developmental control of synaptic vesicle formation
Daly C; Ziff EB
1997 Apr 1;17(7):2365-2375, Journal of neuroscience
— id: 7318, year: 1997, vol: 17, page: 2365, stat: Journal Article,

Density-dependent activation of TRP-2 in mouse melanocytes
Hornyak, TJ; Ziff, EB; Perelman, RO
1997 APR ;108(4):215-215, Journal of investigative dermatology
— id: 53216, year: 1997, vol: 108, page: 215, stat: Journal Article,

Myc represses transcription of the growth arrest gene gas1
Lee TC; Li L; Philipson L; Ziff EB
1997 Nov 25;94(24):12886-12891, Proceedings of the National Academy of Sciences of the United States of America
— id: 11472, year: 1997, vol: 94, page: 12886, stat: Journal Article,

Identification of AMPA interacting proteins by the yeast two hybrid system
Osten, P.; Srivastava, S.; Inman, G. J.; Villim, S.; Lee, L.; Khatri, L.; Ziff, E. B.
1997 ;23(1-2):923-923, Abstracts (Society for Neuroscience)
— id: 92650, year: 1997, vol: 23, page: 923, stat: Journal Article,

Identification of NMDA receptor dominant negative mutations and apoptotic function of the NMDA receptors in CHO cells
Rameau, G. A.; Ziff, E. B.
1997 ;23(1-2):2304-2304, Abstracts (Society for Neuroscience)
— id: 92647, year: 1997, vol: 23, page: 2304, stat: Journal Article,

AMPA receptor interacting protein: PSD 96
Srivastava, Sapna; Villim, Sven; Osten, Pavel; Khatri, Latika; States, Bradley; Inman, Gareth J.; Daly, Chris; Ziff, Edward B.
1997 ;23(1-2):1392-1392, Abstracts (Society for Neuroscience)
— id: 92649, year: 1997, vol: 23, page: 1392, stat: Journal Article,

Nerve growth factor induces transcription of the p21 WAF1/CIP1 and cyclin D1 genes in PC12 cells by activating the Sp1 transcription factor
Yan GZ; Ziff EB
1997 Aug 15;17(16):6122-6132, Journal of neuroscience
— id: 7285, year: 1997, vol: 17, page: 6122, stat: Journal Article,

Enlightening the postsynaptic density
Ziff EB
1997 Dec;19(6):1163-1174, Neuron
— id: 7871, year: 1997, vol: 19, page: 1163, stat: Journal Article,

Chronic FGF-2 treatment increases NMDA receptor desensitization in cultured hippocampal neurons by a cycloheximide-sensitive mechanism that requires calcineurin activity
Boxer, Adam L.; Ziff, Edward B.
1996 ;22(1-3):1959-1959, Abstracts (Society for Neuroscience)
— id: 92652, year: 1996, vol: 22, page: 1959, stat: Journal Article,

Regulated expression of synaptic vesicle proteins in cultured hippocampal neurons
Daly, C.; Ziff, E. B.
1996 ;22(1-3):1949-1949, Abstracts (Society for Neuroscience)
— id: 92653, year: 1996, vol: 22, page: 1949, stat: Journal Article,

Dominant negative mutants of Myc inhibit cooperation of both Myc and adenovirus serotype-5 E1a with Ras
MacGregor D; Li LH; Ziff EB
1996 Apr;167(1):95-105, Journal of cellular physiology
— id: 8005, year: 1996, vol: 167, page: 95, stat: Journal Article,

Expression of neuropeptide FF precursor in rat CNS
Panula, P.; Nieminen, M.; Aarnisalo, A. A.; Lintunen, M.; Karhunen, T.; Vilim, F. S.; Ziff, E.; Karlstedt, K.
1996 ;22(1-3):1557-1557, Abstracts (Society for Neuroscience)
— id: 92651, year: 1996, vol: 22, page: 1557, stat: Journal Article,

Analysis of the bovine and rat neuropeptide FF and AF gene
Vilim, F. S.; Ziff, E.
1996 ;22(1-3):1925-1925, Abstracts (Society for Neuroscience)
— id: 92654, year: 1996, vol: 22, page: 1925, stat: Journal Article,

Pediatric brain tumors express multiple receptor tyrosine kinases including novel cell adhesion kinases
Weiner HL; Rothman M; Miller DC; Ziff EB
1996 Aug;25(2):64-71; discussion 71, Pediatric neurosurgery
— id: 7276, year: 1996, vol: 25, page: 64, stat: Journal Article,

The human papillomavirus type 16 E7 protein complements adenovirus type 5 E1A amino-terminus-dependent transactivation of adenovirus type 5 early genes and increases ATF and Oct-1 DNA binding activity
Wong HK; Ziff EB
1996 Jan;70(1):332-340, Journal of virology
— id: 57385, year: 1996, vol: 70, page: 332, stat: Journal Article,

Basic fibroblast growth factor selectively increases desensitization of NMDA receptor currents in cultured rat hippocampal neurons
Boxer, A. L.; Ziff, E. B.
1995 ;21(1-3):1547-1547, Abstracts (Society for Neuroscience)
— id: 92655, year: 1995, vol: 21, page: 1547, stat: Journal Article,

Regulation of the tyrosine hydroxylase gene requires cooperation between the TH-FSE and CRE
Ghee, M.; Miller, J. C.; Ziff, E. B.
1995 ;21(1-3):92-92, Abstracts (Society for Neuroscience)
— id: 92658, year: 1995, vol: 21, page: 92, stat: Journal Article,

Regulation of cell proliferation and differentiation by Myc
Hopewell R; Li L; MacGregor D; Nerlov C; Ziff EB
1995 ;19:85-89, Journal of cell science. Supplement
— id: 6917, year: 1995, vol: 19, page: 85, stat: Journal Article,

The nerve growth factor-responsive PC12 cell line does not express the Myc dimerization partner Max
Hopewell R; Ziff EB
1995 Jul;15(7):3470-3478, Molecular & cellular biology
— id: 12751, year: 1995, vol: 15, page: 3470, stat: Journal Article,

Raf phosphorylates p53 in vitro and potentiates p53-dependent transcriptional transactivation in vivo
Jamal S; Ziff EB
1995 Jun 1;10(11):2095-2101, Oncogene
— id: 12766, year: 1995, vol: 10, page: 2095, stat: Journal Article,

Cyclin D2 and Ha-Ras transformed rat embryo fibroblasts exhibit a novel deregulation of cell size control and early S phase arrest in low serum
Kerkhoff E; Ziff EB
1995 May 1;14(9):1892-1903, EMBO journal
— id: 6658, year: 1995, vol: 14, page: 1892, stat: Journal Article,

Deregulated messenger RNA expression during T cell apoptosis
Kerkhoff E; Ziff EB
1995 Dec 11;23(23):4857-4863, Nucleic acids research
— id: 8001, year: 1995, vol: 23, page: 4857, stat: Journal Article,

CCAAT/enhancer binding protein-alpha amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells
Nerlov C; Ziff EB
1995 Sep 1;14(17):4318-4328, EMBO journal
— id: 17523, year: 1995, vol: 14, page: 4318, stat: Journal Article,

Cloning of the neuropeptide NPFF and NPAF precursor from bovine, rat, mouse and human
Vilim, F. S.; Ziff, E.
1995 ;21(1-3):760-760, Abstracts (Society for Neuroscience)
— id: 92657, year: 1995, vol: 21, page: 760, stat: Journal Article,

NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1
Yan GZ; Ziff EB
1995 Sep;15(9):6200-6212, Journal of neuroscience
— id: 8053, year: 1995, vol: 15, page: 6200, stat: Journal Article,

NGF inducible regulatory elements in the rat cyclin D1 promoter
Yan, G.-Z.; Ziff, E. B.
1995 ;21(1-3):1049-1049, Abstracts (Society for Neuroscience)
— id: 92656, year: 1995, vol: 21, page: 1049, stat: Journal Article,

Selective down regulation of NMDA receptor currents and NMDAR2B messenger RNA levels by basic fibroblast growth factor in cultured rat hippocampal neurons
Boxer, A. L.; Moreno, H.; Ruby, B.; Ziff, E. B.
1994 ;20(1-2):673-673, Abstracts (Society for Neuroscience)
— id: 92664, year: 1994, vol: 20, page: 673, stat: Journal Article,

Nerve growth factor regulates the expression and activity of p33cdk2 and p34cdc2 kinases in PC12 pheochromocytoma cells
Buchkovich KJ; Ziff EB
1994 Nov;5(11):1225-1241, Molecular biology of the cell
— id: 56616, year: 1994, vol: 5, page: 1225, stat: Journal Article,

Nerve growth factor regulates the expression and kinase activity of p33-cdk2 and p34-cdc2
Buchkovich, K. J.; Ziff, E. B.
1994 ;20(1-2):1481-1481, Abstracts (Society for Neuroscience)
— id: 92659, year: 1994, vol: 20, page: 1481, stat: Journal Article,

Regulation of the tyrosine hydroxylase promoter
Ghee, M.; Miller, J. C.; Ziff, E. B.
1994 ;20(1-2):280-280, Abstracts (Society for Neuroscience)
— id: 92666, year: 1994, vol: 20, page: 280, stat: Journal Article,

Fos family members successively occupy the tyrosine hydroxylase gene AP-1 site after nerve growth factor or epidermal growth factor stimulation and can repress transcription
Gizang-Ginsberg E; Ziff EB
1994 Feb;8(2):249-262, Molecular endocrinology
— id: 56532, year: 1994, vol: 8, page: 249, stat: Journal Article,

Origin of PC12 pheochromocytoma cells: Evidence that loss of the MYC dimerization partner Max was a transforming event
Hopewell, R.; Ziff, E. B.
1994 ;20(1-2):1050-1050, Abstracts (Society for Neuroscience)
— id: 92662, year: 1994, vol: 20, page: 1050, stat: Journal Article,

Regulation of neuronal determination genes in PC12 and P19 cells
Issack, P. S.; Ziff, E. B.
1994 ;20(1-2):1077-1077, Abstracts (Society for Neuroscience)
— id: 92660, year: 1994, vol: 20, page: 1077, stat: Journal Article,

c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II
Li LH; Nerlov C; Prendergast G; MacGregor D; Ziff EB
1994 Sep 1;13(17):4070-4079, EMBO journal
— id: 6680, year: 1994, vol: 13, page: 4070, stat: Journal Article,

Three levels of functional interaction determine the activity of CCAAT/enhancer binding protein-alpha on the serum albumin promoter
Nerlov C; Ziff EB
1994 Feb 1;8(3):350-362, Genes & development
— id: 56569, year: 1994, vol: 8, page: 350, stat: Journal Article,

Defective processing of human adenovirus 2 late transcription unit mRNAs during abortive infections in monkey cells
Ross D; Ziff E
1994 Jul;202(1):107-115, Virology
— id: 6502, year: 1994, vol: 202, page: 107, stat: Journal Article,

Antibodies to the Aplysia neuropeptide myomodulin stain varicose processes in rat brain
Vilim, F. S.; Ziff, E.
1994 ;20(1-2):515-515, Abstracts (Society for Neuroscience)
— id: 92665, year: 1994, vol: 20, page: 515, stat: Journal Article,

Complementary functions of E1a conserved region 1 cooperate with conserved region 3 to activate adenovirus serotype 5 early promoters
Wong HK; Ziff EB
1994 Aug;68(8):4910-4920, Journal of virology
— id: 56604, year: 1994, vol: 68, page: 4910, stat: Journal Article,

A PC12 cells differentiation induced by NGF is associated with induction of cyclin D1 and its complexes
Yan, G-Z.; Ziff, E.
1994 ;20(1-2):675-675, Abstracts (Society for Neuroscience)
— id: 92663, year: 1994, vol: 20, page: 675, stat: Journal Article,

The cloning of multiple protein tyrosine kinase genes expressed in human pediatric brain tumors and developing brain
Ziff, Edward B.; Rothman, Marc; Weiner, Howard L.; McCarthy, Maria
1994 ;20(1-2):1050-1050, Abstracts (Society for Neuroscience)
— id: 92661, year: 1994, vol: 20, page: 1050, stat: Journal Article,

Adenovirus 5 E1A proteins disrupt the neuronal phenotype and growth factor responsiveness of PC12 cells by a conserved region 1-dependent mechanism
Boulukos KE; Ziff EB
1993 Feb;8(2):237-248, Oncogene
— id: 13280, year: 1993, vol: 8, page: 237, stat: Journal Article,

Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain
Ferre-D'Amare AR; Prendergast GC; Ziff EB; Burley SK
1993 May 6;363(6424):38-45, Nature
— id: 17524, year: 1993, vol: 363, page: 38, stat: Journal Article,

DOMINANT NEGATIVE MYC MUTANTS SHED NEW LIGHT ON MYC FUNCTION
MACGREGOR, DN; ZIFF, EB
1993 APR ;41(2):A266-A266, Clinical research
— id: 54272, year: 1993, vol: 41, page: A266, stat: Journal Article,

Biphasic effect of Max on Myc cotransformation activity and dependence on amino- and carboxy-terminal Max functions
Prendergast GC; Hopewell R; Gorham BJ; Ziff EB
1992 Dec;6(12A):2429-2439, Genes & development
— id: 56575, year: 1992, vol: 6, page: 2429, stat: Journal Article,

A new bind for Myc
Prendergast GC; Ziff EB
1992 Mar;8(3):91-96, Trends in genetics
— id: 17525, year: 1992, vol: 8, page: 91, stat: Journal Article,

Defective synthesis of early region 4 mRNAs during abortive adenovirus infections in monkey cells
Ross D; Ziff E
1992 May;66(5):3110-3117, Journal of virology
— id: 13625, year: 1992, vol: 66, page: 3110, stat: Journal Article,

Nerve growth factor-induced derepression of peripherin gene expression is associated with alterations in proteins binding to a negative regulatory element
Thompson MA; Lee E; Lawe D; Gizang-Ginsberg E; Ziff EB
1992 Jun;12(6):2501-2513, Molecular & cellular biology
— id: 13578, year: 1992, vol: 12, page: 2501, stat: Journal Article,

PC12 CELL DIFFERENTIATION IS ALTERED BY ADENOVIRUS-5 E1A PRODUCTS
BOULUKOS K E; ZIFF E B
1991 ;17(1-2):37-37, Abstracts (Society for Neuroscience)
— id: 92667, year: 1991, vol: 17, page: 37, stat: Journal Article,

Differential spatial and temporal expression of two type III intermediate filament proteins in olfactory receptor neurons
Gorham JD; Ziff EB; Baker H
1991 Sep;7(3):485-497, Neuron
— id: 13913, year: 1991, vol: 7, page: 485, stat: Journal Article,

cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription
Metz R; Ziff E
1991 Oct;5(10):1754-1766, Genes & development
— id: 13895, year: 1991, vol: 5, page: 1754, stat: Journal Article,

THE HELIX LOOP HELIX PROTEIN-RE12 AND THE C/EBP-RELATED FACTOR-RNFIL-6 BIND TO NEIGHBORING SITES WITHIN THE C-FOS SERUM RESPONSE ELEMENT
METZ, R; ZIFF, E
1991 DEC ;6(12):2165-2178, Oncogene
— id: 52123, year: 1991, vol: 6, page: 2165, stat: Journal Article,

Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation
Prendergast GC; Lawe D; Ziff EB
1991 May 3;65(3):395-407, Cell
— id: 14025, year: 1991, vol: 65, page: 395, stat: Journal Article,

Mbh 1: a novel gelsolin/severin-related protein which binds actin in vitro and exhibits nuclear localization in vivo
Prendergast GC; Ziff EB
1991 Apr;10(4):757-766, EMBO journal
— id: 14087, year: 1991, vol: 10, page: 757, stat: Journal Article,

Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region
Prendergast GC; Ziff EB
1991 Jan 11;251(4990):186-189, Science
— id: 17526, year: 1991, vol: 251, page: 186, stat: Journal Article,

Nerve growth factor regulates tyrosine hydroxylase gene transcription through a nucleoprotein complex that contains c-Fos
Gizang-Ginsberg E; Ziff EB
1990 Apr;4(4):477-491, Genes & development
— id: 17528, year: 1990, vol: 4, page: 477, stat: Journal Article,

EXPRESSION OF THE NEURONAL INTERMEDIATE FILAMENT PROTEIN IFP PERIPHERIN IN THE RAT CNS AND OLFACTORY NEURONS
GORHAM J D; BAKER H; ZIFF E B
1990 ;16(1):51-51, Abstracts (Society for Neuroscience)
— id: 92668, year: 1990, vol: 16, page: 51, stat: Journal Article,

The expression of the neuronal intermediate filament protein peripherin in the rat embryo
Gorham JD; Baker H; Kegler D; Ziff EB
1990 Dec 15;57(2):235-248, Brain research. Developmental brain research
— id: 14243, year: 1990, vol: 57, page: 235, stat: Journal Article,

TRANSACTIVATION OF C-FOS AND BETA-ACTIN GENES BY RAF AS A STEP IN EARLY RESPONSE TO TRANSMEMBRANE SIGNALS
Jamal, S; Ziff, E
1990 Mar 29;344(6265):463-466, Nature
— id: 31886, year: 1990, vol: 344, page: 463, stat: Journal Article,

Isolation and characterization of eight tumor necrosis factor-induced gene sequences from human fibroblasts
Lee TH; Lee GW; Ziff EB; Vilcek J
1990 May;10(5):1982-1988, Molecular & cellular biology
— id: 15540, year: 1990, vol: 10, page: 1982, stat: Journal Article,

Elevated c-myc expression in childhood medulloblastomas
MacGregor DN; Ziff EB
1990 Jul;28(1):63-68, Pediatric research
— id: 17527, year: 1990, vol: 28, page: 63, stat: Journal Article,

Altered transcriptional activity of c-fos promoter plasmids in v-raf-transformed NIH 3T3 cells
Siegfried Z; Ziff EB
1990 Nov;10(11):6073-6078, Molecular & cellular biology
— id: 14303, year: 1990, vol: 10, page: 6073, stat: Journal Article,

Functional analysis of an isolated fos promoter element with AP-1 site homology reveals cell type-specific transcriptional properties
Velcich A; Ziff EB
1990 Dec;10(12):6273-6282, Molecular & cellular biology
— id: 14264, year: 1990, vol: 10, page: 6273, stat: Journal Article,

Transcription factors: a new family gathers at the cAMP response site
Ziff EB
1990 Mar;6(3):69-72, Trends in genetics
— id: 17529, year: 1990, vol: 6, page: 69, stat: Journal Article,

THE EXPRESSION OF THE NEURONAL INTERMEDIATE FILAMENT PROTEIN PERIPHERIN IN THE DEVELOPING RAT EMBRYO
GORHAM J D; ZIFF E B
1989 ;15(2):1324-1324, Abstracts (Society for Neuroscience)
— id: 92669, year: 1989, vol: 15, page: 1324, stat: Journal Article,

Behind the Fos and Jun leucine zipper
Kouzarides T; Ziff E
1989 Nov;1(3):71-76, Cancer cells
— id: 10449, year: 1989, vol: 1, page: 71, stat: Journal Article,

Leucine zippers of fos, jun and GCN4 dictate dimerization specificity and thereby control DNA binding
Kouzarides T; Ziff E
1989 Aug 17;340(6234):568-571, Nature
— id: 10521, year: 1989, vol: 340, page: 568, stat: Journal Article,

DNA-binding motif
Prendergast GC; Ziff EB
1989 Oct 5;341(6241):392-392, Nature
— id: 17530, year: 1989, vol: 341, page: 392, stat: Journal Article,

Transcription activation by serum, PDGF, and TPA through the c-fos DSE: cell type specific requirements for induction
Siegfried Z; Ziff EB
1989 Jan;4(1):3-11, Oncogene
— id: 10750, year: 1989, vol: 4, page: 3, stat: Journal Article,

Structure of the gene encoding peripherin, an NGF-regulated neuronal-specific type III intermediate filament protein
Thompson MA; Ziff EB
1989 Jan;2(1):1043-1053, Neuron
— id: 10810, year: 1989, vol: 2, page: 1043, stat: Journal Article,

Expression of the K-fgf protooncogene is repressed during differentiation of F9 cells
Velcich A; Delli-Bovi P; Mansukhani A; Ziff EB; Basilico C
1989 ;5(1):31-37, Oncogene research
— id: 10762, year: 1989, vol: 5, page: 31, stat: Journal Article,

The adenovirus-5 12S E1a protein, but not the 13S induces expression of the endoA differentiation marker in F9 cells
Velcich A; Ziff EB
1989 Jun;4(6):707-713, Oncogene
— id: 10607, year: 1989, vol: 4, page: 707, stat: Journal Article,

Dynamic interactions of c-fos protein in serum-stimulated 3T3 cells
Vosatka RJ; Hermanowski-Vosatka A; Metz R; Ziff EB
1989 Mar;138(3):493-502, Journal of cellular physiology
— id: 17531, year: 1989, vol: 138, page: 493, stat: Journal Article,

Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses
Jones NC; Rigby PW; Ziff EB
1988 Mar;2(3):267-281, Genes & development
— id: 17533, year: 1988, vol: 2, page: 267, stat: Journal Article,

The role of the leucine zipper in the fos-jun interaction
Kouzarides T; Ziff E
1988 Dec 15;336(6200):646-651, Nature
— id: 10861, year: 1988, vol: 336, page: 646, stat: Journal Article,

A nerve growth factor-regulated messenger RNA encodes a new intermediate filament protein
Leonard DG; Gorham JD; Cole P; Greene LA; Ziff EB
1988 Jan;106(1):181-193, Journal of cell biology
— id: 11216, year: 1988, vol: 106, page: 181, stat: Journal Article,

GENE-REGULATION BY GROWTH-FACTORS
Metz, R; Gorham, J; Siegfried, Z; Leonard, D; Gizangginsberg, E; Thompson, MA; Lawe, D; Kouzarides, T; Vosatka, R; Macgregor, D; Jamal, S; Greenberg, ME; Ziff, EB
1988 Jul-Aug;53(4):727-737, Cold Spring Harbor symposia on quantitative biology
— id: 31623, year: 1988, vol: 53, page: 727, stat: Journal Article,

Microinjection of fos-specific antibodies blocks DNA synthesis in fibroblast cells
Riabowol KT; Vosatka RJ; Ziff EB; Lamb NJ; Feramisco JR
1988 Apr;8(4):1670-1676, Molecular & cellular biology
— id: 17532, year: 1988, vol: 8, page: 1670, stat: Journal Article,

The amino-terminal region of the adenovirus serotype 5 E1a protein performs two separate functions when expressed in primary baby rat kidney cells
Smith DH; Ziff EB
1988 Sep;8(9):3882-3890, Molecular & cellular biology
— id: 10983, year: 1988, vol: 8, page: 3882, stat: Journal Article,

Adenovirus E1a ras cooperation activity is separate from its positive and negative transcription regulatory functions
Velcich A; Ziff E
1988 May;8(5):2177-2183, Molecular & cellular biology
— id: 11117, year: 1988, vol: 8, page: 2177, stat: Journal Article,

Nuclear oncogenes
Alt, Frederick W.; Harlow, Edward.; Ziff, Edward
Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory, 1987,
— id: 376, year: 1987, vol: , page: , stat: ,

Mutation of the c-fos gene dyad symmetry element inhibits serum inducibility of transcription in vivo and the nuclear regulatory factor binding in vitro
Greenberg ME; Siegfried Z; Ziff EB
1987 Mar;7(3):1217-1225, Molecular & cellular biology
— id: 17534, year: 1987, vol: 7, page: 1217, stat: Journal Article,

Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells
Leonard DG; Ziff EB; Greene LA
1987 Sep;7(9):3156-3167, Molecular & cellular biology
— id: 11371, year: 1987, vol: 7, page: 3156, stat: Journal Article,

MOLECULAR-CLONING OF RAT DOPAMINE BETA-HYDROXYLASE CDNA
Mcmahon, A; Kuhn, LJ; Leonard, DGB; Ziff, EB; Sabban, EL
1987 May 1;46(6):2136-2136, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 31188, year: 1987, vol: 46, page: 2136, stat: Journal Article,

Alternative modes of c-myc regulation in growth factor-stimulated and differentiating cells
Nepveu A; Levine RA; Campisi J; Greenberg ME; Ziff EB; Marcu KB
1987 ;1(3):243-250, Oncogene
— id: 17536, year: 1987, vol: 1, page: 243, stat: Journal Article,

Repression of insulin gene expression by adenovirus type 5 E1a proteins
Stein RW; Ziff EB
1987 Mar;7(3):1164-1170, Molecular & cellular biology
— id: 17535, year: 1987, vol: 7, page: 1164, stat: Journal Article,

Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription
Greenberg ME; Hermanowski AL; Ziff EB
1986 Apr;6(4):1050-1057, Molecular & cellular biology
— id: 17538, year: 1986, vol: 6, page: 1050, stat: Journal Article,

Stimulation of neuronal acetylcholine receptors induces rapid gene transcription
Greenberg ME; Ziff EB; Greene LA
1986 Oct 3;234(4772):80-83, Science
— id: 17537, year: 1986, vol: 234, page: 80, stat: Journal Article,

CHARACTERIZATION OF NERVE GROWTH FACTOR-REGULATED MESSENGER RNA SPECIES
LEONARD D G B; GREENE L A; ZIFF E B
1986 ;12(1):215-215, Abstracts (Society for Neuroscience)
— id: 92671, year: 1986, vol: 12, page: 215, stat: Journal Article,

MOLECULAR CLONING OF NILE GLYCOPROTEIN-RELATED COMPLEMENTARY DNA PROBES
SAJOVIC P; ENNULAT D J; LEONARD D G B; KAPLAN K; PROCHIANTZ A L; ZIFF E B; SHELANSKI M L; GREENE L A
1986 ;12(2):1459-1459, Abstracts (Society for Neuroscience)
— id: 92670, year: 1986, vol: 12, page: 1459, stat: Journal Article,

Adenovirus E1a proteins repress expression from polyomavirus early and late promoters
Velcich A; Kern FG; Basilico C; Ziff EB
1986 Nov;6(11):4019-4025, Molecular & cellular biology
— id: 14432, year: 1986, vol: 6, page: 4019, stat: Journal Article,

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells
Greenberg ME; Greene LA; Ziff EB
1985 Nov 15;260(26):14101-14110, Journal of biological chemistry
— id: 17539, year: 1985, vol: 260, page: 14101, stat: Journal Article,

GENES REGULATED BY NERVE GROWTH FACTOR IN PC-12 CELLS
LEONARD D G B; GREENE L A; ZIFF E B
1985 ;11(2):1116-1116, Abstracts (Society for Neuroscience)
— id: 92672, year: 1985, vol: 11, page: 1116, stat: Journal Article,

Vector expression of adenovirus type 5 E1a proteins: evidence for E1a autoregulation
Smith DH; Kegler DM; Ziff EB
1985 Oct;5(10):2684-2696, Molecular & cellular biology
— id: 17540, year: 1985, vol: 5, page: 2684, stat: Journal Article,

ADENOVIRUS E1A PROTEINS REPRESS TRANSCRIPTION FROM THE SV40 EARLY PROMOTER
VELCICH, A; ZIFF, E
1985 ;40(3):705-716, Cell
— id: 41235, year: 1985, vol: 40, page: 705, stat: Journal Article,

Splicing in adenovirus and other animal viruses
Ziff EB
1985 ;93(10):327-358, International review of cytology
— id: 17541, year: 1985, vol: 93, page: 327, stat: Journal Article,

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
Greenberg ME; Ziff EB
1984 Oct 4-10;311(5985):433-438, Nature
— id: 17543, year: 1984, vol: 311, page: 433, stat: Journal Article,

HeLa cell beta-tubulin gene transcription is stimulated by adenovirus 5 in parallel with viral early genes by an E1a-dependent mechanism
Stein R; Ziff EB
1984 Dec;4(12):2792-2801, Molecular & cellular biology
— id: 17542, year: 1984, vol: 4, page: 2792, stat: Journal Article,

REPRESSION OF ACTIVATORS
VELCICH, A; ZIFF, E
1984 ;312(5995):594-595, Nature
— id: 40868, year: 1984, vol: 312, page: 594, stat: Journal Article,

SEQUENCE ARRANGEMENT AND PROTEIN CODING CAPACITY OF THE ADENOVIRUS TYPE-2 I-LEADER
Falvey, E; Ziff, E
1983 ;45(1):185-191, Journal of virology
— id: 30694, year: 1983, vol: 45, page: 185, stat: Journal Article,

Poly(A) sites of adenovirus serotype 2 transcription units
Fraser NW; Baker CC; Moore MA; Ziff EB
1982 Mar 5;155(3):207-233, Journal of molecular biology
— id: 17545, year: 1982, vol: 155, page: 207, stat: Journal Article,

Selective inhibition of adenovirus type 2 early region II and III transcription by an anisomycin block of protein synthesis
Shaw AR; Ziff EB
1982 Jul;2(7):789-799, Molecular & cellular biology
— id: 17544, year: 1982, vol: 2, page: 789, stat: Journal Article,

Promoters and heterogeneous 5' termini of the messenger RNAs of adenovirus serotype 2
Baker CC; Ziff EB
1981 Jun 25;149(2):189-221, Journal of molecular biology
— id: 17547, year: 1981, vol: 149, page: 189, stat: Journal Article,

In vitro transcription of adenovirus
Fire A; Baker CC; Manley JL; Ziff EB; Sharp PA
1981 Dec;40(3):703-719, Journal of virology
— id: 17546, year: 1981, vol: 40, page: 703, stat: Journal Article,

Biogenesis, structures, and sites of encoding of the 5' termini of adenovirus-2 mRNAs
Baker CC; Ziff EB
1980 ;44 Pt 1(5782):415-428, Cold Spring Harbor symposia on quantitative biology
— id: 17550, year: 1980, vol: 44 Pt 1, page: 415, stat: Journal Article,

Transcripts from the adenovirus-2 major late promoter yield a single early family of 3' coterminal mRNAs and five late families
Shaw AR; Ziff EB
1980 Dec;22(3):905-916, Cell
— id: 17548, year: 1980, vol: 22, page: 905, stat: Journal Article,

Transcription and RNA processing by the DNA tumour viruses
Ziff EB
1980 Oct 9;287(5782):491-499, Nature
— id: 17549, year: 1980, vol: 287, page: 491, stat: Journal Article,

Coincidence of the promoter and capped 5' terminus of RNA from the adenovirus 2 major late transcription unit
Ziff EB; Evans RM
1978 Dec;15(4):1463-1475, Cell
— id: 17551, year: 1978, vol: 15, page: 1463, stat: Journal Article,

Gene F of bacteriophage phiX174. Correlation of nucleotide sequences from the DNA and amino acid sequences from the gene product
Air GM; Blackburn EH; Coulson AR; Galibert F; Sanger F; Sedat JW; Ziff EB
1976 Nov 15;107(4):445-458, Journal of molecular biology
— id: 17552, year: 1976, vol: 107, page: 445, stat: Journal Article,

Determination of the nucleotide sequence of a fragment of bacteriophage phiX 174 DNA
Ziff EB; Sedat JW; Galibert F
1973 Jan 10;241(106):34-37, Nature: new biology
— id: 17553, year: 1973, vol: 241, page: 34, stat: Journal Article,

A method for locating 4-thiouridylate in the primary structure of transfer ribonucleic acids
Ziff EB; Fresco JR
1969 Aug;8(8):3242-3248, Biochemistry
— id: 17554, year: 1969, vol: 8, page: 3242, stat: Journal Article,

Chemical transformation of 4-thiouracil nucleosides to uracil and cytosine counterparts
Ziff EB; Fresco JR
1968 Dec 18;90(26):7338-7342, Journal of the American Chemical Society
— id: 17555, year: 1968, vol: 90, page: 7338, stat: Journal Article,