Biosketch / Results /
Bruce YoungSilverman Professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology
Obstetrics and Gynecology
530 First Avenue
New York, NY 10016
Research SummaryFetal blood of different gestational ages was tested for immunoreactivity and compared with maternal blood responses to immune stimulators. The data will help with transplatation of stem cells, autoimmune disease,asthma, and preterm birth Mid-trimester amniotic fluid was cultured in various media, frozen, thawed with retention of stem cell function and induced to neural and osteocyte fates. Studies are underway to determine therapeutic effectiveness of transplanting neural progenitors derived from amniotic fluid stem cells in correcting neurological damage. Factors controlling longevity and cell death in amniotic fluid cultures are being studied by Affymetrix gene analysis and quantitative PCR for genes related to senesence.
Research InterestsLuteal phase defects,pregnancy loss, fetal physiology, endoscopic surgery,immunology, stem cells derived from amniotic fluid & umbilical cord blood inducible to a neural fate.
Identification and isolation of putative stem cells from the murine placenta
Proudfit, Christine L; Chan, Michael K; Basch, Ross S; Young, Bruce K
2014-10-01; 0300-5577,Journal of perinatal medicine - id: 1258672, year: 2014 JOURNAL ARTICLE
Young, Bruce K
2015-01-07; 0300-5577,Journal of perinatal medicine - id: 1423672, year: 2014 Editorial
Amniotic fluid derived cells: genome-wide expression in early and late cultures
Jadhav, Ashwin; Zavadil, Jiri; Basch, Ross; Young, Bruce
2013-02-22; 0002-9378,American journal of obstetrics & gynecology - id: 221782, year: 2013
Stem cell markers in amniotic fluid derived cells
Jadhav A.; Basch R.; Chan M.; Strelchenko N.; Chen Z.; Young B.
2012-02-05; 0002-9378,American journal of obstetrics & gynecology - id: 149828, year: 2012
Co-ordinate expression of Th1/Th2 phenotypes in maternal and fetal blood: Evidence for a transplacental nexus
Jadhav A.; Young B.; Tse D.
2012-02-05; 0002-9378,American journal of obstetrics & gynecology - id: 149830, year: 2012