Bruce Kenneth Young

Biosketch / Results /

Bruce Young

Silverman Professor of Obstetrics and Gynecology, Department of Obstetrics and Gynecology
Obstetrics and Gynecology

Contact Info

Address
530 First Avenue
New York, NY 10016

212/263-6359

Research Summary

Fetal blood of different gestational ages was tested for immunoreactivity and compared with maternal blood responses to immune stimulators. The data will help with transplatation of stem cells, autoimmune disease,asthma, and preterm birth Mid-trimester amniotic fluid was cultured in various media, frozen, thawed with retention of stem cell function and induced to neural and osteocyte fates. Studies are underway to determine therapeutic effectiveness of transplanting neural progenitors derived from amniotic fluid stem cells in correcting neurological damage. Factors controlling longevity and cell death in amniotic fluid cultures are being studied by Affymetrix gene analysis and quantitative PCR for genes related to senesence.

Research Interests

Luteal phase defects,pregnancy loss, fetal physiology, endoscopic surgery,immunology, stem cells derived from amniotic fluid & umbilical cord blood inducible to a neural fate.

Identification and isolation of putative stem cells from the murine placenta
Proudfit, Christine L; Chan, Michael K; Basch, Ross S; Young, Bruce K
2014-10-01; 0300-5577,Journal of perinatal medicine - id: 1258672, year: 2014 JOURNAL ARTICLE

Guest editorial
Young, Bruce K
2015-01-07; 0300-5577,Journal of perinatal medicine - id: 1423672, year: 2014 Editorial

Amniotic fluid derived cells: genome-wide expression in early and late cultures
Jadhav, Ashwin; Zavadil, Jiri; Basch, Ross; Young, Bruce
2013-02-22; 0002-9378,American journal of obstetrics & gynecology - id: 221782, year: 2013

Stem cell markers in amniotic fluid derived cells
Jadhav A.; Basch R.; Chan M.; Strelchenko N.; Chen Z.; Young B.
2012-02-05; 0002-9378,American journal of obstetrics & gynecology - id: 149828, year: 2012

Co-ordinate expression of Th1/Th2 phenotypes in maternal and fetal blood: Evidence for a transplacental nexus
Jadhav A.; Young B.; Tse D.
2012-02-05; 0002-9378,American journal of obstetrics & gynecology - id: 149830, year: 2012