Biosketch / Results /

Andrew Varga

Adjunct Instructor, Department of Medicine

Contact Info

Address
462 First Avenue
New York, NY 10016

212-263-8423
Andrew.Varga@nyumc.org

Research Summary

Dr. Varga has a longstanding interest in mechanisms of learning and memory and the role of sleep in memory consolidation. He has an active research program both on the systems level in human subjects and on the molecular level in collaboration with Dr. Eric Klann at NYU's Center for Neural Science. His clinical interests involve all areas of sleep medicine with particular interest in movement disorders in sleep (RLS, REM Behavior Disorder), sleep in neurodegenerative diseases (such as Alzheimer Disease and Parkinson Disease), and generalized cognitive deficits as a function of fragmented sleep.

Research Keywords

sleep, memory, aging, neurodegenerative disease

Bipolar cell gap junctions serve major signaling pathways in the human retina
Kantor, O; Varga, A; Nitschke, R; Naumann, A; Enzsoly, A; Lukats, A; Szabo, A; Nemeth, J; Volgyi, B. Bipolar cell gap junctions serve major signaling pathways in the human retina. Brain structure & function. 2017 Jan 10;(pp(1-22):1-22 (2416212)

Reduced Slow-Wave Sleep Is Associated with High Cerebrospinal Fluid Abeta42 Levels in Cognitively Normal Elderly
Varga, Andrew W; Wohlleber, Margaret E; Gimenez, Sandra; Romero, Sergio; Alonso, Joan F; Ducca, Emma L; Kam, Korey; Lewis, Clifton; Tanzi, Emily B; Tweardy, Samuel; Kishi, Akifumi; Parekh, Ankit; Fischer, Esther; Gumb, Tyler; Alcolea, Daniel; Fortea, Juan; Lleo, Alberto; Blennow, Kaj; Zetterberg, Henrik; Mosconi, Lisa; Glodzik, Lidia; Pirraglia, Elizabeth; Burschtin, Omar E; de Leon, Mony J; Rapoport, David M; Lu, Shou-En; Ayappa, Indu; Osorio, Ricardo S. Reduced Slow-Wave Sleep Is Associated with High Cerebrospinal Fluid Abeta42 Levels in Cognitively Normal Elderly. Sleep. 2016 Nov 01;39(11):2041-2048 (2310172)

Orexin-A is Associated With Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects
Osorio, Ricardo S; Ducca, Emma L; Wohlleber, Margaret E; Tanzi, Emily B; Gumb, Tyler; Twumasi, Akosua; Tweardy, Samuel; Lewis, Clifton; Fischer, Esther; Koushyk, Viachaslau; Cuartero-Toledo, Maria; Sheikh, Mohammed O; Pirraglia, Elizabeth; Zetterberg, Henrik; Blennow, Kaj; Lu, Shou-En; Mosconi, Lisa; Glodzik, Lidia; Schuetz, Sonja; Varga, Andrew W; Ayappa, Indu; Rapoport, David M; de Leon, Mony J. Orexin-A is Associated With Increases in Cerebrospinal Fluid Phosphorylated-Tau in Cognitively Normal Elderly Subjects. Sleep. 2016 Jun 01;39(6):1253-1260 (2046522)

Effects of aging on slow-wave sleep dynamics and human spatial navigational memory consolidation
Varga, Andrew W; Ducca, Emma L; Kishi, Akifumi; Fischer, Esther; Parekh, Ankit; Koushyk, Viachaslau; Yau, Po Lai; Gumb, Tyler; Leibert, David P; Wohlleber, Margaret E; Burschtin, Omar E; Convit, Antonio; Rapoport, David M; Osorio, Ricardo S; Ayappa, Indu. Effects of aging on slow-wave sleep dynamics and human spatial navigational memory consolidation. Neurobiology of aging. 2016 Jun;42:142-149 (2100842)

Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's disease
Cedernaes, Jonathan; Osorio, Ricardo S; Varga, Andrew W; Kam, Korey; Schioth, Helgi B; Benedict, Christian. Candidate mechanisms underlying the association between sleep-wake disruptions and Alzheimer's disease. Sleep medicine reviews. 2016 Feb 11;31:102-111 (2051902)