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Andrew Varga

Adjunct Instructor, Department of Medicine
Medicine

Contact Info

Address
462 First Avenue
New York, NY 10016

Research Summary

Dr. Varga has a longstanding interest in mechanisms of learning and memory and the role of sleep in memory consolidation. He has an active research program both on the systems level in human subjects and on the molecular level in collaboration with Dr. Eric Klann at NYU's Center for Neural Science. His clinical interests involve all areas of sleep medicine with particular interest in movement disorders in sleep (RLS, REM Behavior Disorder), sleep in neurodegenerative diseases (such as Alzheimer Disease and Parkinson Disease), and generalized cognitive deficits as a function of fragmented sleep.

Research Keywords

sleep, memory, aging, neurodegenerative disease

CSF Abeta42 levels may increase due to agedependent slow-wave sleep loss priorto amyloid deposition in humans
Osorio, R S; Wohlleber, M; Gimenez, S; Romero, S; Ducca, E L; Gumb, T; Parekh, A; Varga, A; Burschtin, O; Ayappa, I; Rapoport, D M; De, Leon M. CSF Abeta42 levels may increase due to agedependent slow-wave sleep loss priorto amyloid deposition in humans [Meeting Abstract]. Alzheimer's & dementia. 2015 July 2015;11(7):P848-P848 (1923912)

Sleep-disordered breathing advances cognitive decline in the elderly
Osorio, Ricardo S; Gumb, Tyler; Pirraglia, Elizabeth; Varga, Andrew W; Lu, Shou-En; Lim, Jason; Wohlleber, Margaret E; Ducca, Emma L; Koushyk, Viachaslau; Glodzik, Lidia; Mosconi, Lisa; Ayappa, Indu; Rapoport, David M; de Leon, Mony J. Sleep-disordered breathing advances cognitive decline in the elderly. Neurology. 2015 Apr;84(19):1964-1971 (1533162)

Apnea induced REM sleep disruption impairs human spatial navigational memory
Varga, A; Kishi, A; Mantua, J; Lim, J; Koushyk, V; Leibert, D; Osorio, R; Rapoport, D; Ayappa, I. Apnea induced REM sleep disruption impairs human spatial navigational memory [Meeting Abstract]. Sleep medicine. 2015 December 2015;16:S4-S5 (1923522)

Role of sleep in the clearance of brain waste byproducts and the link with late onset alzheimer's disease
Osorio, R S; Ayappa, I A; Gumb, T; Varga, A; Glodzik, L; Rapoport, D M; De, Leon M J. Role of sleep in the clearance of brain waste byproducts and the link with late onset alzheimer's disease [Meeting Abstract]. American journal of respiratory & critical care medicine. 2014 2014;189:- (1824282)

The interaction between sleep-disordered breathing and apolipoprotein E genotype on cerebrospinal fluid biomarkers for Alzheimer's disease in cognitively normal elderly individuals
Osorio, Ricardo S; Ayappa, Indu; Mantua, Janna; Gumb, Tyler; Varga, Andrew; Mooney, Anne M; Burschtin, Omar E; Taxin, Zachary; During, Emmanuel; Spector, Nicole; Biagioni, Milton; Pirraglia, Elizabeth; Lau, Hiuyan; Zetterberg, Henrik; Blennow, Kaj; Lu, Shou-En; Mosconi, Lisa; Glodzik, Lidia; Rapoport, David M; de Leon, Mony J. The interaction between sleep-disordered breathing and apolipoprotein E genotype on cerebrospinal fluid biomarkers for Alzheimer's disease in cognitively normal elderly individuals. Neurobiology of aging. 2014 Jun;35(6):1318-1324 (851792)