Sergio Trombetta, Ph.D.

Inflammatory Spleen Monocytes Can Upregulate CD11c Expression Without Converting into Dendritic Cells
Drutman, Scott B; Kendall, Julia C; Trombetta, E Sergio
2012 Apr;188(8):3603-3610, Journal of immunology
— id: 164347, year: 2012, vol: 188, page: 3603, stat: Journal Article,

Dendritic cells continue to capture and present antigens after maturation in vivo
Drutman, Scott B; Trombetta, E Sergio
2010 Aug 15;185(4):2140-2146, Journal of immunology
— id: 111544, year: 2010, vol: 185, page: 2140, stat: Journal Article,

Cross-talk between the endocytic pathway and the endoplasmic reticulum in cross-presentation by MHC class I molecules
Monu, Ngozi; Trombetta, E Sergio
2007 Feb;19(1):66-72, Current opinion in immunology
— id: 105452, year: 2007, vol: 19, page: 66, stat: Journal Article,

Enhancing immunogenicity by limiting susceptibility to lysosomal proteolysis
Delamarre, Lelia; Couture, Rachael; Mellman, Ira; Trombetta, E Sergio
2006 Sep 4;203(9):2049-2055, Journal of experimental medicine
— id: 105453, year: 2006, vol: 203, page: 2049, stat: Journal Article,

CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis
Shim, Jae-Hyuck; Xiao, Changchun; Hayden, Matthew S; Lee, Ki-Young; Trombetta, E Sergio; Pypaert, Marc; Nara, Atsuki; Yoshimori, Tamotsu; Wilm, Bettina; Erdjument-Bromage, Hediye; Tempst, Paul; Hogan, Brigid L M; Mellman, Ira; Ghosh, Sankar
2006 Mar 27;172(7):1045-1056, Journal of cell biology
— id: 105454, year: 2006, vol: 172, page: 1045, stat: Journal Article,

Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate
Delamarre, Lelia; Pack, Margit; Chang, Henry; Mellman, Ira; Trombetta, E Sergio
2005 Mar 11;307(5715):1630-1634, Science
— id: 62721, year: 2005, vol: 307, page: 1630, stat: Journal Article,

Cell biology of antigen processing in vitro and in vivo
Trombetta, E Sergio; Mellman, Ira
2005 ;23:975-1028, Annual review of immunology
— id: 62720, year: 2005, vol: 23, page: 975, stat: Journal Article,

Glycoprotein reglucosylation
Trombetta, E Sergio; Parodi, Armando J
2005 Apr;35(4):328-337, Methods
— id: 62719, year: 2005, vol: 35, page: 328, stat: Journal Article,

Expression profiling reveals novel pathways in the transformation of melanocytes to melanomas
Hoek, Keith; Rimm, David L; Williams, Kenneth R; Zhao, Hongyu; Ariyan, Stephan; Lin, Aiping; Kluger, Harriet M; Berger, Aaron J; Cheng, Elaine; Trombetta, E Sergio; Wu, Terence; Niinobe, Michio; Yoshikawa, Kazuaki; Hannigan, Gregory E; Halaban, Ruth
2004 Aug 1;64(15):5270-5282, Cancer research
— id: 62722, year: 2004, vol: 64, page: 5270, stat: Journal Article,

Nucleoside diphosphatase and glycosyltransferase activities can localize to different subcellular compartments in Schizosaccharomyces pombe
D'Alessio, Cecilia; Trombetta, Eduardo S; Parodi, Armando J
2003 Jun 20;278(25):22379-22387, Journal of biological chemistry
— id: 62725, year: 2003, vol: 278, page: 22379, stat: Journal Article,

The contribution of N-glycans and their processing in the endoplasmic reticulum to glycoprotein biosynthesis
Trombetta, E Sergio
2003 Sep;13(9):77R-91R, Glycobiology
— id: 62724, year: 2003, vol: 13, page: 77R, stat: Journal Article,

Activation of lysosomal function during dendritic cell maturation
Trombetta, E Sergio; Ebersold, Melanie; Garrett, Wendy; Pypaert, Marc; Mellman, Ira
2003 Feb 28;299(5611):1400-1403, Science
— id: 62726, year: 2003, vol: 299, page: 1400, stat: Journal Article,

Quality control and protein folding in the secretory pathway
Trombetta, E Sergio; Parodi, Armando J
2003 ;19:649-676, Annual review of cell & developmental biology
— id: 62723, year: 2003, vol: 19, page: 649, stat: Journal Article,

Abnormal acidification of melanoma cells induces tyrosinase retention in the early secretory pathway
Halaban, Ruth; Patton, Robin S; Cheng, Elaine; Svedine, Sherri; Trombetta, E Sergio; Wahl, Miriam L; Ariyan, Stephen; Hebert, Daniel N
2002 Apr 26;277(17):14821-14828, Journal of biological chemistry
— id: 62728, year: 2002, vol: 277, page: 14821, stat: Journal Article,

Quaternary and domain structure of glycoprotein processing glucosidase II
Trombetta ES; Fleming KG; Helenius A
2001 Sep 4;40(35):10717-10722, Biochemistry
— id: 62729, year: 2001, vol: 40, page: 10717, stat: Journal Article,

N-glycan processing and glycoprotein folding
Trombetta ES; Parodi AJ
2001 ;59:303-344, Advances in protein chemistry
— id: 62727, year: 2001, vol: 59, page: 303, stat: Journal Article,

Conformational requirements for glycoprotein reglucosylation in the endoplasmic reticulum
Trombetta ES; Helenius A
2000 Mar 20;148(6):1123-1129, Journal of cell biology
— id: 62730, year: 2000, vol: 148, page: 1123, stat: Journal Article,

Genetic evidence for the heterodimeric structure of glucosidase II. The effect of disrupting the subunit-encoding genes on glycoprotein folding
D'Alessio C; Fernandez F; Trombetta ES; Parodi AJ
1999 Sep 3;274(36):25899-25905, Journal of biological chemistry
— id: 62731, year: 1999, vol: 274, page: 25899, stat: Journal Article,

Glycoprotein reglucosylation and nucleotide sugar utilization in the secretory pathway: identification of a nucleoside diphosphatase in the endoplasmic reticulum
Trombetta ES; Helenius A
1999 Jun 15;18(12):3282-3292, EMBO journal
— id: 62732, year: 1999, vol: 18, page: 3282, stat: Journal Article,

Lectins as chaperones in glycoprotein folding
Trombetta ES; Helenius A
1998 Oct;8(5):587-592, Current opinion in structural biology
— id: 62733, year: 1998, vol: 8, page: 587, stat: Journal Article,

N-linked oligosaccharides are necessary and sufficient for association of glycosylated forms of bovine RNase with calnexin and calreticulin
Rodan AR; Simons JF; Trombetta ES; Helenius A
1996 Dec 16;15(24):6921-6930, EMBO journal
— id: 62734, year: 1996, vol: 15, page: 6921, stat: Journal Article,

Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, conserved from yeast to mammals, and a tightly bound noncatalytic HDEL-containing subunit
Trombetta ES; Simons JF; Helenius A
1996 Nov 1;271(44):27509-27516, Journal of biological chemistry
— id: 62735, year: 1996, vol: 271, page: 27509, stat: Journal Article,