Yajaira Suarez, Ph.D.

MicroRNAs in Metabolic Disease
Fernandez-Hernando, Carlos; Ramirez, Cristina M; Goedeke, Leigh; Suarez, Yajaira
2013 Feb;33(2):178-185, Arteriosclerosis, thrombosis, & vascular biology
— id: 221462, year: 2013, vol: 33, page: 178, stat: Journal Article,

A regulatory role for miRNA-33* in controlling lipid metabolism gene expression
Goedeke, Leigh; Vales-Lara, Frances M; Fenstermaker, Michael; Cirera-Salinas, Daniel; Chamorro-Jorganes, Aranzazu; Ramirez, Cristina M; Mattison, Julie A; de Cabo, Rafael; Suarez, Yajaira; Fernandez-Hernando, Carlos
2013 Apr;:2339-2352, Molecular & cellular biology
— id: 287532, year: 2013, vol: , page: 2339, stat: Journal Article,

Control of Cholesterol Metabolism and Plasma HDL Levels by miRNA-144
Ramirez, Cristina M; Rotllan, Noemi; Vlassov, Alexander V; Davalos, Alberto; Li, Mu; Goedeke, Leigh; Aranda, Juan F; Cirera-Salinas, Daniel; Araldi, Elisa; Salerno, Alessandro; Wanschel, Amarylis Claudine Bonito Azeredo; Zavadil, Jiri; Castrillo, Antonio; Jungsu, Kim; Suarez, Yajaira; Fernandez-Hernando, Carlos
2013 Mar;:1417-1419, Circulation research
— id: 287552, year: 2013, vol: , page: 1417, stat: Journal Article,

Mir-33 regulates cell proliferation and cell cycle progression
Cirera-Salinas, D; Pauta, M; Allen, RM; Salerno, AG; Ramirez, CM; Chamorro-Jorganes, A; Wanschel, AC; Lasuncion, MA; Morales-Ruiz, M; Suarez, Y; Baldan, A; Esplugues, E; Fernandez-Hernando, C
2012 Mar;11(5):922-933, Cell cycle
— id: 163698, year: 2012, vol: 11, page: 922, stat: Journal Article,

miR-1 and miR-206 regulate angiogenesis by modulating VegfA expression in zebrafish
Stahlhut, Carlos; Suarez, Yajaira; Lu, Jun; Mishima, Yuichiro; Giraldez, Antonio J
2012 Dec;139(23):4356-4364, Development
— id: 183502, year: 2012, vol: 139, page: 4356, stat: Journal Article,

New insights into microRNA-29 regulation: a new key player in cardiovascular disease
Suarez, Yajaira; Fernandez-Hernando, Carlos
2012 Mar;52(3):584-586, Journal of molecular & cellular cardiology
— id: 164275, year: 2012, vol: 52, page: 584, stat: Journal Article,

MicroRNA-16 and MicroRNA-424 Regulate Cell-Autonomous Angiogenic Functions in Endothelial Cells via Targeting Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1
Chamorro-Jorganes, Aranzazu; Araldi, Elisa; Penalva, Luiz O F; Sandhu, Devraj; Fernandez-Hernando, Carlos; Suarez, Yajaira
2011 Nov;31(11):2595-2606, Arteriosclerosis, thrombosis, & vascular biology
— id: 139472, year: 2011, vol: 31, page: 2595, stat: Journal Article,

miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling
Davalos, Alberto; Goedeke, Leigh; Smibert, Peter; Ramirez, Cristina M; Warrier, Nikhil P; Andreo, Ursula; Cirera-Salinas, Daniel; Rayner, Katey; Suresh, Uthra; Pastor-Pareja, Jose Carlos; Esplugues, Enric; Fisher, Edward A; Penalva, Luiz O F; Moore, Kathryn J; Suarez, Yajaira; Lai, Eric C; Fernandez-Hernando, Carlos
2011 May 31;108(22):9232-9237, Proceedings of the National Academy of Sciences of the United States of America
— id: 133351, year: 2011, vol: 108, page: 9232, stat: Journal Article,

MicroRNAs in lipid metabolism
Fernandez-Hernando, Carlos; Suarez, Yajaira; Rayner, Katey J; Moore, Kathryn J
2011 Apr;22(2):86-92, Current opinion in lipidology
— id: 128788, year: 2011, vol: 22, page: 86, stat: Journal Article,

The role of microRNAs in cholesterol efflux and hepatic lipid metabolism
Moore, Kathryn J; Rayner, Katey J; Suarez, Yajaira; Fernandez-Hernando, Carlos
2011 Aug 21;31:49-63, Annual review of nutrition
— id: 138339, year: 2011, vol: 31, page: 49, stat: Journal Article,

MicroRNA-758 Regulates Cholesterol Efflux Through Posttranscriptional Repression of ATP-Binding Cassette Transporter A1
Ramirez, Cristina M; Davalos, Alberto; Goedeke, Leigh; Salerno, Alessandro G; Warrier, Nikhil; Cirera-Salinas, Daniel; Suarez, Yajaira; Fernandez-Hernando, Carlos
2011 Nov;31(11):2707-2714, Arteriosclerosis, thrombosis, & vascular biology
— id: 139473, year: 2011, vol: 31, page: 2707, stat: Journal Article,

Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
Rayner, Katey J; Sheedy, Frederick J; Esau, Christine C; Hussain, Farah N; Temel, Ryan E; Parathath, Saj; van Gils, Janine M; Rayner, Alistair J; Chang, Aaron N; Suarez, Yajaira; Fernandez-Hernando, Carlos; Fisher, Edward A; Moore, Kathryn J
2011 Jul 1;121(7):2921-2931, Journal of clinical investigation
— id: 136939, year: 2011, vol: 121, page: 2921, stat: Journal Article,

MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function
Albinsson, Sebastian; Suarez, Yajaira; Skoura, Athanasia; Offermanns, Stefan; Miano, Joseph M; Sessa, William C
2010 Jun;30(6):1118-1126, Arteriosclerosis, thrombosis, & vascular biology
— id: 110673, year: 2010, vol: 30, page: 1118, stat: Journal Article,

microRNAs and cholesterol metabolism
Moore, Kathryn J; Rayner, Katey J; Suarez, Yajaira; Fernandez-Hernando, Carlos
2010 Dec;21(12):699-706, Trends in endocrinology & metabolism
— id: 138240, year: 2010, vol: 21, page: 699, stat: Journal Article,

Mir-33 Coordinates Genes Regulating Cholesterol Homeostasis
Rayner, Katey J.; Suarez, Yajaira; Davalos, Alberto; Parathath, Saj; Fitzgerald, Michael L.; Tamehiro, Norimasa; Fisher, Edward A.; Moore, Kathryn J.; Fernandez-Hernando, Carlos
2010 NOV ;30(11):E191-E191, Arteriosclerosis, thrombosis, & vascular biology
— id: 117305, year: 2010, vol: 30, page: E191, stat: Journal Article,

MiR-33 contributes to the regulation of cholesterol homeostasis
Rayner, Katey J; Suarez, Yajaira; Davalos, Alberto; Parathath, Saj; Fitzgerald, Michael L; Tamehiro, Norimasa; Fisher, Edward A; Moore, Kathryn J; Fernandez-Hernando, Carlos
2010 Jun 18;328(5985):1570-1573, Science
— id: 138135, year: 2010, vol: 328, page: 1570, stat: Journal Article,

Microregulation of plaque neovascularization
Suarez, Yajaira
2010 Aug;30(8):1500-1501, Arteriosclerosis, thrombosis, & vascular biology
— id: 110882, year: 2010, vol: 30, page: 1500, stat: Journal Article,

Cutting Edge: TNF-Induced MicroRNAs Regulate TNF-Induced Expression of E-Selectin and Intercellular Adhesion Molecule-1 on Human Endothelial Cells: Feedback Control of Inflammation
Suarez, Yajaira; Wang, Chen; Manes, Thomas D; Pober, Jordan S
2010 Jan 1;184(1):21-25, Journal of immunology
— id: 105695, year: 2010, vol: 184, page: 21, stat: Journal Article,

Genetic evidence supporting a critical role of endothelial caveolin-1 during the progression of atherosclerosis
Fernandez-Hernando, Carlos; Yu, Jun; Suarez, Yajaira; Rahner, Christoph; Davalos, Alberto; Lasuncion, Miguel A; Sessa, William C
2009 Jul;10(1):48-54, Cell metabolism
— id: 103238, year: 2009, vol: 10, page: 48, stat: Journal Article,

Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking
Harrison, Kenneth D; Miao, Robert Qing; Fernandez-Hernando, Carlos; Suarez, Yajaira; Davalos, Alberto; Sessa, William C
2009 Sep;10(3):208-218, Cell metabolism
— id: 103241, year: 2009, vol: 10, page: 208, stat: Journal Article,

MicroRNAs as novel regulators of angiogenesis
Suarez, Yajaira; Sessa, William C
2009 Feb 27;104(4):442-454, Circulation research
— id: 104080, year: 2009, vol: 104, page: 442, stat: Journal Article,

Reticulon 4B (Nogo-B) is necessary for macrophage infiltration and tissue repair
Yu, Jun; Fernandez-Hernando, Carlos; Suarez, Yajaira; Schleicher, Michael; Hao, Zhengrong; Wright, Paulette L; DiLorenzo, Annarita; Kyriakides, Themis R; Sessa, William C
2009 Oct 13;106(41):17511-17516, Proceedings of the National Academy of Sciences of the United States of America
— id: 103244, year: 2009, vol: 106, page: 17511, stat: Journal Article,

Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence
Schleicher, Michael; Shepherd, Benjamin R; Suarez, Yajaira; Fernandez-Hernando, Carlos; Yu, Jun; Pan, Yong; Acevedo, Lisette M; Shadel, Gerald S; Sessa, William C
2008 Jan 14;180(1):101-112, Journal of cell biology
— id: 103213, year: 2008, vol: 180, page: 101, stat: Journal Article,

Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis
Suarez, Yajaira; Fernandez-Hernando, Carlos; Yu, Jun; Gerber, Scott A; Harrison, Kenneth D; Pober, Jordan S; Iruela-Arispe, M Luisa; Merkenschlager, Matthias; Sessa, William C
2008 Sep 16;105(37):14082-14087, Proceedings of the National Academy of Sciences of the United States of America
— id: 103223, year: 2008, vol: 105, page: 14082, stat: Journal Article,

Loss of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease
Fernandez-Hernando, Carlos; Ackah, Eric; Yu, Jun; Suarez, Yajaira; Murata, Takahisa; Iwakiri, Yasuko; Prendergast, Jay; Miao, Robert Q; Birnbaum, Morris J; Sessa, William C
2007 Dec;6(6):446-457, Cell metabolism
— id: 103211, year: 2007, vol: 6, page: 446, stat: Journal Article,

Proteomic analysis of the resistance to aplidin in human cancer cells
Gonzalez-Santiago, Laura; Alfonso, Patricia; Suarez, Yajaira; Nunez, Antonio; Garcia-Fernandez, Luis F; Alvarez, Enrique; Munoz, Alberto; Casal, J Ignacio
2007 Apr;6(4):1286-1294, Journal of proteome research
— id: 104013, year: 2007, vol: 6, page: 1286, stat: Journal Article,

Vitamin D regulates the phenotype of human breast cancer cells
Pendas-Franco, Natalia; Gonzalez-Sancho, Jose Manuel; Suarez, Yajaira; Aguilera, Oscar; Steinmeyer, Andreas; Gamallo, Carlos; Berciano, Maria T; Lafarga, Miguel; Munoz, Alberto
2007 Mar;75(3):193-207, Differentiation
— id: 104010, year: 2007, vol: 75, page: 193, stat: Journal Article,

Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells
Suarez, Yajaira; Fernandez-Hernando, Carlos; Pober, Jordan S; Sessa, William C
2007 Apr 27;100(8):1164-1173, Circulation research
— id: 103202, year: 2007, vol: 100, page: 1164, stat: Journal Article,

Alloimmunity to human endothelial cells derived from cord blood progenitors
Suarez, Yajaira; Shepherd, Benjamin R; Rao, Deepak A; Pober, Jordan S
2007 Dec 1;179(11):7488-7496, Journal of immunology
— id: 104036, year: 2007, vol: 179, page: 7488, stat: Journal Article,

Aplidin induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 phosphatase downregulation
Gonzalez-Santiago, L; Suarez, Y; Zarich, N; Munoz-Alonso, M J; Cuadrado, A; Martinez, T; Goya, L; Iradi, A; Saez-Tormo, G; Maier, J V; Moorthy, A; Cato, A C B; Rojas, J M; Munoz, A
2006 Nov;13(11):1968-1981, Cell death & differentiation
— id: 104490, year: 2006, vol: 13, page: 1968, stat: Journal Article,

Vascularization and engraftment of a human skin substitute using circulating progenitor cell-derived endothelial cells
Shepherd, Benjamin R; Enis, David R; Wang, Feiya; Suarez, Yajaira; Pober, Jordan S; Schechner, Jeffrey S
2006 Aug;20(10):1739-1741, FASEB journal
— id: 103980, year: 2006, vol: 20, page: 1739, stat: Journal Article,

Plitidepsin cellular binding and Rac1/JNK pathway activation depend on membrane cholesterol content
Suarez, Yajaira; Gonzalez-Santiago, Laura; Zarich, Natasha; Davalos, Alberto; Aranda, Juan F; Alonso, Miguel A; Lasuncion, Miguel A; Rojas, Jose Maria; Munoz, Alberto
2006 Nov;70(5):1654-1663, Molecular pharmacology
— id: 103991, year: 2006, vol: 70, page: 1654, stat: Journal Article,

Lovastatin-induced PC-12 cell differentiation is associated with RhoA/RhoA kinase pathway inactivation
Fernandez-Hernando, Carlos; Suarez, Yajaira; Lasuncion, Miguel A
2005 Aug;29(4):591-602, Molecular & cellular neurosciences
— id: 103186, year: 2005, vol: 29, page: 591, stat: Journal Article,

Sterol stringency of proliferation and cell cycle progression in human cells
Suarez, Yajaira; Fernandez, Carlos; Ledo, Beatriz; Martin, Miguel; Gomez-Coronado, Diego; Lasuncion, Miguel A
2005 May 15;1734(2):203-213, Biochimica & biophysica acta
— id: 103953, year: 2005, vol: 1734, page: 203, stat: Journal Article,

JNK activation is critical for Aplidin-induced apoptosis
Cuadrado, Ana; Gonzalez, Laura; Suarez, Yajaira; Martinez, Teresa; Munoz, Alberto
2004 Jun 10;23(27):4673-4680, Oncogene
— id: 103922, year: 2004, vol: 23, page: 4673, stat: Journal Article,

Synergistic upregulation of low-density lipoprotein receptor activity by tamoxifen and lovastatin
Suarez, Yajaira; Fernandez, Carlos; Gomez-Coronado, Diego; Ferruelo, Antonio J; Davalos, Alberto; Martinez-Botas, Javier; Lasuncion, Miguel A
2004 Nov 1;64(2):346-355, Cardiovascular research
— id: 103932, year: 2004, vol: 64, page: 346, stat: Journal Article,

Aplidin induces apoptosis in human cancer cells via glutathione depletion and sustained activation of the epidermal growth factor receptor, Src, JNK, and p38 MAPK
Cuadrado, Ana; Garcia-Fernandez, Luis F; Gonzalez, Laura; Suarez, Yajaira; Losada, Alejandro; Alcaide, Victoria; Martinez, Teresa; Fernandez-Sousa, Jose Maria; Sanchez-Puelles, Jose Maria; Munoz, Alberto
2003 Jan 3;278(1):241-250, Journal of biological chemistry
— id: 103888, year: 2003, vol: 278, page: 241, stat: Journal Article,

Apoptosis by anticancer drugs. Review
Gonzalez-Santiago L; Suarez Y; Cuadrado A; Martinez T; Munoz A
2003 ;2(1):17-42, Applied genomics & proteomics
— id: 104499, year: 2003, vol: 2, page: 17, stat: Journal Article,

Kahalalide F, a new marine-derived compound, induces oncosis in human prostate and breast cancer cells
Suarez, Yajaira; Gonzalez, Laura; Cuadrado, Ana; Berciano, Maite; Lafarga, Miguel; Munoz, Alberto
2003 Sep;2(9):863-872, Molecular cancer therapeutics
— id: 103909, year: 2003, vol: 2, page: 863, stat: Journal Article,

A double mutant [N543H+2393del9] allele in the LDL receptor gene in familial hypercholesterolemia: effect on plasma cholesterol levels and cardiovascular disease
Castillo, S; Reyes, G; Tejedor, D; Mozas, P; Suarez, Y; Lasuncion, M A; Cenarro, A; Civeira, F; Alonso, R; Mata, P; Pocovi, M
2002 Dec;20(6):477-477, Human mutation
— id: 104491, year: 2002, vol: 20, page: 477, stat: Journal Article,

Inhibition of cholesterol biosynthesis by Delta22-unsaturated phytosterols via competitive inhibition of sterol Delta24-reductase in mammalian cells
Fernandez, Carlos; Suarez, Yajaira; Ferruelo, Antonio J; Gomez-Coronado, Diego; Lasuncion, Miguel A
2002 Aug 15;366(Pt 1):109-119, Biochemical journal
— id: 103883, year: 2002, vol: 366, page: 109, stat: Journal Article,

Comparacion de dos ensayos funcionales del receptor de lipoproteinas de baja densidad para el diagnostico del la hipercolesterolemia familiar
Suarez Y; Lasuncion MA
2002 ;14:123-124, Clinica e investigacion en arteriosclerosis
— id: 104498, year: 2002, vol: 14, page: 123, stat: Journal Article,

Differential effects of ergosterol and cholesterol on Cdk1 activation and SRE-driven transcription
Suarez, Yajaira; Fernandez, Carlos; Ledo, Beatriz; Ferruelo, Antonio J; Martin, Miguel; Vega, Miguel A; Gomez-Coronado, Diego; Lasuncion, Miguel A
2002 Mar;269(6):1761-1771, European journal of biochemistry
— id: 103870, year: 2002, vol: 269, page: 1761, stat: Journal Article,

Dose-dependent effects of lovastatin on cell cycle progression. Distinct requirement of cholesterol and non-sterol mevalonate derivatives