R. Theodore Smith, M.D.

HYPERAUTOFLUORESCENT RING IN AUTOIMMUNE RETINOPATHY
Lima LH; Greenberg JP; Greenstein VC; Smith RT; Sallum JM; Thirkill C; Yannuzzi LA; Tsang SH
2012 Jan 3;:1385-1394 #, Retina
— id: 148688, year: 2012, vol: , page: 1385, stat: Journal Article,

Disruption in Bruch membrane in patients with Stargardt disease
Park SP; Chang S; Allikmets R; Smith RT; Burke TR; Gregory-Roberts E; Tsang SH
2012 Mar;33(1):49-52, Ophthalmic Genetics
— id: 149060, year: 2012, vol: 33, page: 49, stat: Journal Article,

Quantification of peripapillary sparing and macular involvement in Stargardt disease (STGD1)
Burke, Tomas R; Rhee, David W; Smith, R Theodore; Tsang, Stephen H; Allikmets, Rando; Chang, Stanley; Lazow, Margot A; Hood, Donald C; Greenstein, Vivienne C
2011 ;52(11):8006-8015, Investigative ophthalmology & visual science. IOVS
— id: 148693, year: 2011, vol: 52, page: 8006, stat: Journal Article,

Quantitative measurements of autofluorescence with the scanning laser ophthalmoscope
Delori, Francois; Greenberg, Jonathan P; Woods, Russell L; Fischer, Jorg; Duncker, Tobias; Sparrow, Janet; Smith, R Theodore
2011 ;52(13):9379-9390, Investigative ophthalmology & visual science. IOVS
— id: 149058, year: 2011, vol: 52, page: 9379, stat: Journal Article,

Recovery of macular pigment spectrum in vivo using hyperspectral image analysis
Fawzi, Amani A; Lee, Noah; Acton, Jennifer H; Laine, Andrew F; Smith, R Theodore
2011 Oct;16(10):106008-106008, Journal of biomedical optics
— id: 149061, year: 2011, vol: 16, page: 106008, stat: Journal Article,

A prospective study of reticular macular disease
Pumariega, Nicole M; Smith, R Theodore; Sohrab, Mahsa A; Letien, Valerie; Souied, Eric H
2011 Aug;118(8):1619-1625, Ophthalmology
— id: 149064, year: 2011, vol: 118, page: 1619, stat: Journal Article,

Decoding simulated neurodynamics predicts the perceptual consequences of age-related macular degeneration
Shi, Jianing V; Wielaard, Jim; Smith, R Theodore; Sajda, Paul
2011 ;11(14):4-4, Journal of vision
— id: 149059, year: 2011, vol: 11, page: 4, stat: Journal Article,

Complement factor H 402H variant and reticular macular disease
Smith, R Theodore; Merriam, Joanna E; Sohrab, Mahsa A; Pumariega, Nicole M; Barile, Gaetano; Blonska, Anna M; Haans, Raymond; Madigan, David; Allikmets, Rando
2011 Aug;129(8):1061-1066, Archives of ophthalmology (1960)
— id: 149063, year: 2011, vol: 129, page: 1061, stat: Journal Article,

Drusen analysis in a human-machine synergistic framework
Smith, R Theodore; Sohrab, Mahsa A; Pumariega, Nicole M; Mathur, Kanika; Haans, Raymond; Blonska, Anna; Uy, Karl; Despriet, Dominiek; Klaver, Caroline
2011 Jan;129(1):40-47, Archives of ophthalmology (1960)
— id: 149067, year: 2011, vol: 129, page: 40, stat: Journal Article,

Imaging characteristics of dry age-related macular degeneration
Sohrab, Mahsa A; Smith, R Theodore; Fawzi, Amani A
2011 May;26(3):156-166, Seminars in ophthalmology
— id: 149066, year: 2011, vol: 26, page: 156, stat: Journal Article,

Image registration and multimodal imaging of reticular pseudodrusen
Sohrab, Mahsa A; Smith, R Theodore; Salehi-Had, Hani; Sadda, SriniVas R; Fawzi, Amani A
2011 Jul;52(8):5743-5748, Investigative ophthalmology & visual science. IOVS
— id: 149065, year: 2011, vol: 52, page: 5743, stat: Journal Article,

Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration
Yu, Yi; Bhangale, Tushar R; Fagerness, Jesen; Ripke, Stephan; Thorleifsson, Gudmar; Tan, Perciliz L; Souied, Eric H; Richardson, Andrea J; Merriam, Joanna E; Buitendijk, Gabrielle H S; Reynolds, Robyn; Raychaudhuri, Soumya; Chin, Kimberly A; Sobrin, Lucia; Evangelou, Evangelos; Lee, Phil H; Lee, Aaron Y; Leveziel, Nicolas; Zack, Donald J; Campochiaro, Betsy; Campochiaro, Peter; Smith, R Theodore; Barile, Gaetano R; Guymer, Robyn H; Hogg, Ruth; Chakravarthy, Usha; Robman, Luba D; Gustafsson, Omar; Sigurdsson, Haraldur; Ortmann, Ward; Behrens, Timothy W; Stefansson, Kari; Uitterlinden, Andre G; van Duijn, Cornelia M; Vingerling, Johannes R; Klaver, Caroline C W; Allikmets, Rando; Brantley, Milam A Jr; Baird, Paul N; Katsanis, Nicholas; Thorsteinsdottir, Unnur; Ioannidis, John P A; Daly, Mark J; Graham, Robert R; Seddon, Johanna M
2011 Sep 15;20(18):3699-3709, Human molecular genetics
— id: 149062, year: 2011, vol: 20, page: 3699, stat: Journal Article,

The ERCC6 gene and age-related macular degeneration
Baas, Dominique C; Despriet, Dominiek D; Gorgels, Theo G M F; Bergeron-Sawitzke, Julie; Uitterlinden, Andre G; Hofman, Albert; van Duijn, Cornelia M; Merriam, Joanna E; Smith, R Theodore; Barile, Gaetano R; ten Brink, Jacoline B; Vingerling, Johannes R; Klaver, Caroline C W; Allikmets, Rando; Dean, Michael; Bergen, Arthur A B
2010 ;5(11):e13786-e13786, PLoS ONE
— id: 149070, year: 2010, vol: 5, page: e13786, stat: Journal Article,

The complement component 5 gene and age-related macular degeneration
Baas, Dominique C; Ho, Lintje; Ennis, Sarah; Merriam, Joanna E; Tanck, Michael W T; Uitterlinden, Andre G; de Jong, Paulus T V M; Cree, Angela J; Griffiths, Helen L; Rivadeneira, Fernando; Hofman, Albert; van Duijn, Cornelia; Smith, R Theodore; Barile, Gaetano R; Gorgels, Theo G M F; Vingerling, Johannes R; Klaver, Caroline C W; Lotery, Andrew J; Allikmets, Rando; Bergen, Arthur A B
2010 Mar;117(3):500-511, Ophthalmology
— id: 149076, year: 2010, vol: 117, page: 500, stat: Journal Article,

Loss of peripapillary sparing in non-group I Stargardt disease
Burke, Tomas R; Allikmets, Rando; Smith, R Theodore; Gouras, Peter; Tsang, Stephen H
2010 Nov;91(5):592-600, Experimental eye research
— id: 149069, year: 2010, vol: 91, page: 592, stat: Journal Article,

A partial intensity invariant feature descriptor for multimodal retinal image registration
Chen, Jian; Tian, Jie; Lee, Noah; Zheng, Jian; Smith, R Theodore; Laine, Andrew F
2010 Jul;57(7):1707-1718, IEEE transactions on biomedical engineering
— id: 149072, year: 2010, vol: 57, page: 1707, stat: Journal Article,

Quantitative comparison of drusen segmented on SD-OCT versus drusen delineated on color fundus photographs
Jain, Nieraj; Farsiu, Sina; Khanifar, Aziz A; Bearelly, Srilaxmi; Smith, R Theodore; Izatt, Joseph A; Toth, Cynthia A
2010 Oct;51(10):4875-4883, Investigative ophthalmology & visual science. IOVS
— id: 149071, year: 2010, vol: 51, page: 4875, stat: Journal Article,

Color contrast and drusen area
Mitrut, Izabela; Verma, Amit; Madill, Stephen; Smith, R Theodore; Chong, N Victor
2010 Jun;117(6):1280-1281, Ophthalmology
— id: 149073, year: 2010, vol: 117, page: 1280, stat: Journal Article,

Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)
Neale, Benjamin M; Fagerness, Jesen; Reynolds, Robyn; Sobrin, Lucia; Parker, Margaret; Raychaudhuri, Soumya; Tan, Perciliz L; Oh, Edwin C; Merriam, Joanna E; Souied, Eric; Bernstein, Paul S; Li, Binxing; Frederick, Jeanne M; Zhang, Kang; Brantley, Milam A Jr; Lee, Aaron Y; Zack, Donald J; Campochiaro, Betsy; Campochiaro, Peter; Ripke, Stephan; Smith, R Theodore; Barile, Gaetano R; Katsanis, Nicholas; Allikmets, Rando; Daly, Mark J; Seddon, Johanna M
2010 Apr 20;107(16):7395-7400, Proceedings of the National Academy of Sciences of the United States of America
— id: 149074, year: 2010, vol: 107, page: 7395, stat: Journal Article,

Dynamic soft drusen remodelling in age-related macular degeneration
Smith, R Theodore; Sohrab, Mahsa A; Pumariega, Nicole; Chen, Yue; Chen, Jian; Lee, Noah; Laine, Andrew
2010 Dec;94(12):1618-1623, British journal of ophthalmology
— id: 149068, year: 2010, vol: 94, page: 1618, stat: Journal Article,

Preimplantation genetic diagnosis for stargardt disease
Sohrab, Mahsa A; Allikmets, Rando; Guarnaccia, Michael M; Smith, R Theodore
2010 Apr;149(4):651-655.e2, American journal of ophthalmology
— id: 149075, year: 2010, vol: 149, page: 651, stat: Journal Article,

A comparison of fundus autofluorescence and retinal structure in patients with Stargardt disease
Gomes, Nuno L; Greenstein, Vivienne C; Carlson, Joshua N; Tsang, Stephen H; Smith, R Theodore; Carr, Ronald E; Hood, Donald C; Chang, Stanley
2009 Aug;50(8):3953-3959, Investigative ophthalmology & visual science. IOVS
— id: 148699, year: 2009, vol: 50, page: 3953, stat: Journal Article,

Peripapillary atrophy in Stargardt disease
Hwang, John C; Zernant, Jana; Allikmets, Rando; Barile, Gaetano R; Chang, Stanley; Smith, R Theodore
2009 Feb;29(2):181-186, Retina
— id: 149079, year: 2009, vol: 29, page: 181, stat: Journal Article,

Structural assessment of hyperautofluorescent ring in patients with retinitis pigmentosa
Lima, Luiz H; Cella, Wener; Greenstein, Vivienne C; Wang, Nan-Kai; Busuioc, Mihai; Smith, R Theodore; Yannuzzi, Lawrence A; Tsang, Stephen H
2009 Jul-Aug;29(7):1025-1031, Retina
— id: 103405, year: 2009, vol: 29, page: 1025, stat: Journal Article,

Lipofuscin and autofluorescence metrics in progressive STGD
Smith, R Theodore; Gomes, Nuno L; Barile, Gaetano; Busuioc, Mihai; Lee, Noah; Laine, Andrew
2009 Aug;50(8):3907-3914, Investigative ophthalmology & visual science. IOVS
— id: 149078, year: 2009, vol: 50, page: 3907, stat: Journal Article,

Reticular macular disease
Smith, R Theodore; Sohrab, Mahsa A; Busuioc, Mihai; Barile, Gaetano
2009 Nov;148(5):733-743.e2, American journal of ophthalmology
— id: 149077, year: 2009, vol: 148, page: 733, stat: Journal Article,

Comprehensive analysis of the candidate genes CCL2, CCR2, and TLR4 in age-related macular degeneration
Despriet, Dominiek D G; Bergen, Arthur A B; Merriam, Joanna E; Zernant, Jana; Barile, Gaetano R; Smith, R Theodore; Barbazetto, Irene A; van Soest, Simone; Bakker, Arne; de Jong, Paulus T V M; Allikmets, Rando; Klaver, Caroline C W
2008 Jan;49(1):364-371, Investigative ophthalmology & visual science. IOVS
— id: 149082, year: 2008, vol: 49, page: 364, stat: Journal Article,

PREFERRED RETINAL LOCUS IN MACULAR DISEASE: Characteristics and Clinical Implications
Greenstein, Vivienne C; Santos, Rodrigo A V; Tsang, Stephen H; Smith, R Theodore; Barile, Gaetano R; Seiple, William
2008 Oct;28(9):1234-1240, Retina
— id: 94011, year: 2008, vol: 28, page: 1234, stat: Journal Article,

Interactive segmentation for geographic atrophy in retinal fundus images
Lee N; Smith RT; Laine AF
2008 Oct;2008(42):655-658, Conference record (Asilomar Conference on Signals, Systems & Computers)
— id: 149081, year: 2008, vol: 2008, page: 655, stat: Journal Article,

Interactive Image Analysis in Age-related Macular Degeneration (AMD) and Stargardt Disease (STGD)
Smith RT; Lee N; Chen J; Busuioc M; Laine AF
2008 Oct 26;42:651-654, Conference record (Asilomar Conference on Signals, Systems & Computers)
— id: 149080, year: 2008, vol: 42, page: 651, stat: Journal Article,

A hybrid segmentation approach for geographic atrophy in fundus auto-fluorescence images for diagnosis of age-related macular degeneration
Lee, Noah; Laine, Andrew F; Smith, R Theodore
2007 ;2007:4965-4968, Conference Proceedings (IEEE Engineering in Medicine & Biology Society)
— id: 149083, year: 2007, vol: 2007, page: 4965, stat: Journal Article,

Autofluorescence of basal laminar drusen
Meyerle, Catherine B; Smith, R Theodore; Barbazetto, Irene A; Yannuzzi, Lawrence A
2007 Oct;27(8):1101-1106, Retina
— id: 94073, year: 2007, vol: 27, page: 1101, stat: Journal Article,

Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
Gold, Bert; Merriam, Joanna E; Zernant, Jana; Hancox, Lisa S; Taiber, Andrew J; Gehrs, Karen; Cramer, Kevin; Neel, Julia; Bergeron, Julie; Barile, Gaetano R; Smith, R Theodore; Hageman, Gregory S; Dean, Michael; Allikmets, Rando
2006 Apr;38(4):458-462, Nature genetics
— id: 149087, year: 2006, vol: 38, page: 458, stat: Journal Article,

Optical coherence tomography in asteroid hyalosis
Hwang, John C; Barile, Gaetano R; Schiff, William M; Ober, Michael D; Smith, R Theodore; Del Priore, Lucian V; Turano, Michael R; Chang, Stanley
2006 Jul-Aug;26(6):661-665, Retina
— id: 149085, year: 2006, vol: 26, page: 661, stat: Journal Article,

Predictive value of fundus autofluorescence for development of geographic atrophy in age-related macular degeneration
Hwang, John Chopin; Chan, Jackie W K; Chang, Stanley; Smith, R Theodore
2006 Jun;47(6):2655-2661, Investigative ophthalmology & visual science. IOVS
— id: 149086, year: 2006, vol: 47, page: 2655, stat: Journal Article,

Autofluorescence characteristics of early, atrophic, and high-risk fellow eyes in age-related macular degeneration
Smith, R Theodore; Chan, Jackie K; Busuoic, Mihai; Sivagnanavel, Vasuki; Bird, Alan C; Chong, N Victor
2006 Dec;47(12):5495-5504, Investigative ophthalmology & visual science. IOVS
— id: 149084, year: 2006, vol: 47, page: 5495, stat: Journal Article,

A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
Hageman, Gregory S; Anderson, Don H; Johnson, Lincoln V; Hancox, Lisa S; Taiber, Andrew J; Hardisty, Lisa I; Hageman, Jill L; Stockman, Heather A; Borchardt, James D; Gehrs, Karen M; Smith, Richard J H; Silvestri, Giuliana; Russell, Stephen R; Klaver, Caroline C W; Barbazetto, Irene; Chang, Stanley; Yannuzzi, Lawrence A; Barile, Gaetano R; Merriam, John C; Smith, R Theodore; Olsh, Adam K; Bergeron, Julie; Zernant, Jana; Merriam, Joanna E; Gold, Bert; Dean, Michael; Allikmets, Rando
2005 May 17;102(20):7227-7232, Proceedings of the National Academy of Sciences of the United States of America
— id: 103424, year: 2005, vol: 102, page: 7227, stat: Journal Article,

Automated detection of macular drusen using geometric background leveling and threshold selection
Smith, R Theodore; Chan, Jackie K; Nagasaki, Takayuki; Ahmad, Umer F; Barbazetto, Irene; Sparrow, Janet; Figueroa, Marta; Merriam, Joanna
2005 Feb;123(2):200-206, Archives of ophthalmology (1960)
— id: 149089, year: 2005, vol: 123, page: 200, stat: Journal Article,

Autofluorescence characteristics of normal foveas and reconstruction of foveal autofluorescence from limited data subsets
Smith, R Theodore; Koniarek, Jan P; Chan, Jackie; Nagasaki, Takayuki; Sparrow, Janet R; Langton, Kevin
2005 Aug;46(8):2940-2946, Investigative ophthalmology & visual science. IOVS
— id: 149088, year: 2005, vol: 46, page: 2940, stat: Journal Article,

Photographic patterns in macular images: representation by a mathematical model
Smith, R Theodore; Nagasaki, Takayuki; Sparrow, Janet R; Barbazetto, Irene; Koniarek, Jan P; Bickmann, Lee J
2004 Jan-Feb;9(1):162-172, Journal of biomedical optics
— id: 149090, year: 2004, vol: 9, page: 162, stat: Journal Article,

Vasoproliferative tumor of the retima treated with PDT
Barbezetto, Irene A; Smith, R Theodore
2003 Aug;23(4):565-567, Retina
— id: 149091, year: 2003, vol: 23, page: 565, stat: Journal Article,

A method of drusen measurement based on the geometry of fundus reflectance
Smith, R Theodore; Nagasaki, Takayuki; Sparrow, Janet R; Barbazetto, Irene; Klaver, Caroline C W; Chan, Jackie K
2003 Apr 18;2:10-10, Biomedical engineering online
— id: 149092, year: 2003, vol: 2, page: 10, stat: Journal Article,

Comprehensive genetic analysis of nuclear receptor genes in age-related maculopathy
Wandel, EN; Klaver, CCW; Merriam, JE; Smith, RT; Yannuzzi, LA; Barbazetto, IA; Allikmets, R
2003 ;44(12):1505-1505, Investigative ophthalmology & visual science. IOVS
— id: 103702, year: 2003, vol: 44, page: 1505, stat: Journal Article,

VITREOUS OPACIFICATION IN FAMILIAL AMYLOIDOTIC POLYNEUROPATHY - A NEW TRANSTHYRETIN MUTATION
HERBERT, J; SMITH, RT; YOUNGER, D; HAYS, AP; MARTONE, RL; IZUMOTO, S
1992 ;33(4):860-860, Investigative ophthalmology & visual science. IOVS
— id: 120597, year: 1992, vol: 33, page: 860, stat: Journal Article,

Familial amyloidotic polyneuropathy presenting with carpal tunnel syndrome and a new transthyretin mutation, asparagine 70
Izumoto, S; Younger, D; Hays, A P; Martone, R L; Smith, R T; Herbert, J
1992 Nov;42(11):2094-2102, Neurology
— id: 120552, year: 1992, vol: 42, page: 2094, stat: Journal Article,

Quantification of macular ischaemia in sickle cell retinopathy
Lee CM; Charles HC; Smith RT; Peachey NS; Cunha-Vaz JG; Goldberg MF
1987 Jul;71(7):540-545, British journal of ophthalmology
— id: 66418, year: 1987, vol: 71, page: 540, stat: Journal Article,

Quantification of diabetic macular edema
Smith RT; Lee CM; Charles HC; Farber M; Cunha-Vaz JG
1987 Feb;105(2):218-222, Archives of ophthalmology (1960)
— id: 66419, year: 1987, vol: 105, page: 218, stat: Journal Article,