Jane Skok

Biosketch / Results /

Jane Skok

Professor, Department of Pathology
Co-Dir Path Grand Rounds & Seminars

Contact Info

Address
550 First Avenue
New York, NY 10016

212/263-0504
Jane.Skok@nyumc.org

Research Interests

Nuclear Organisation of immunoglobulin genes

CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci
Fu, Yi; Rocha, Pedro P; Luo, Vincent M; Raviram, Ramya; Deng, Yan; Mazzoni, Esteban O; Skok, Jane A. CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci. Nature communications. 2016 ;7:11707-11707 (2114572)

Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation
Proudhon, Charlotte; Snetkova, Valentina; Raviram, Ramya; Lobry, Camille; Badri, Sana; Jiang, Tingting; Hao, Bingtao; Trimarchi, Thomas; Kluger, Yuval; Aifantis, Iannis; Bonneau, Richard; Skok, Jane A. Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation. Cell reports. 2016 May 26;15(10):2159-2169 (2125032)

4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments
Raviram, Ramya; Rocha, Pedro P; Muller, Christian L; Miraldi, Emily R; Badri, Sana; Fu, Yi; Swanzey, Emily; Proudhon, Charlotte; Snetkova, Valentina; Bonneau, Richard; Skok, Jane A. 4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments. PLoS computational biology. 2016 Mar 3;12(3):e1004780-e1004780 e1004780 (2009402)

A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination
Rocha, Pedro P; Raviram, Ramya; Fu, Yi; Kim, JungHyun; Luo, Vincent M; Aljoufi, Arafat; Swanzey, Emily; Pasquarella, Alessandra; Balestrini, Alessia; Miraldi, Emily R; Bonneau, Richard; Petrini, John; Schotta, Gunnar; Skok, Jane A. A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination. Cell reports. 2016 Jun 16;16(1):48-55 (2159012)

Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination
Thomas-Claudepierre, Anne-Sophie; Robert, Isabelle; Rocha, Pedro P; Raviram, Ramya; Schiavo, Ebe; Heyer, Vincent; Bonneau, Richard; Luo, Vincent M; Reddy, Janardan K; Borggrefe, Tilman; Skok, Jane A; Reina-San-Martin, Bernardo. Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination. Journal of experimental medicine. 2016 Feb 22;213(3):303-312 (2045732)