Jane Skok

Biosketch / Results /

Jane Skok

Professor, Department of Pathology
Co-Dir Path Grand Rounds & Seminars

Contact Info

Address
550 First Avenue
New York, NY 10016

212/263-0504
Jane.Skok@nyumc.org

Research Interests

Nuclear Organisation of immunoglobulin genes

Research Keywords

genome integrity, genomics, immunology, stem cell biology, systems biology

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis
Aranda-Orgilles, Beatriz; Saldana-Meyer, Ricardo; Wang, Eric; Trompouki, Eirini; Fassl, Anne; Lau, Stephanie; Mullenders, Jasper; Rocha, Pedro P; Raviram, Ramya; Guillamot, Maria; Sanchez-Diaz, Maria; Wang, Kun; Kayembe, Clarisse; Zhang, Nan; Amoasii, Leonela; Choudhuri, Avik; Skok, Jane A; Schober, Markus; Reinberg, Danny; Sicinski, Piotr; Schrewe, Heinrich; Tsirigos, Aristotelis; Zon, Leonard I; Aifantis, Iannis. MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis. Cell stem cell. 2016 Dec 01;19(6):784-799 (2232392)

miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation
Coffre, Maryaline; Benhamou, David; Riess, David; Blumenberg, Lili; Snetkova, Valentina; Hines, Marcus J; Chakraborty, Tirtha; Bajwa, Sofia; Jensen, Kari; Chong, Mark M W; Getu, Lelise; Silverman, Gregg J; Blelloch, Robert; Littman, Dan R; Calado, Dinis; Melamed, Doron; Skok, Jane A; Rajewsky, Klaus; Koralov, Sergei B. miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation. Cell reports. 2016 Nov 22;17(9):2271-2285 (2314502)

Identification of multi-loci hubs from 4C-seq demonstrates the functional importance of simultaneous interactions
Jiang, Tingting; Raviram, Ramya; Snetkova, Valentina; Rocha, Pedro P; Proudhon, Charlotte; Badri, Sana; Bonneau, Richard; Skok, Jane A; Kluger, Yuval. Identification of multi-loci hubs from 4C-seq demonstrates the functional importance of simultaneous interactions. Nucleic acids research. 2016 Oct 14;44(18):8714-8725 (2185482)

A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination
Rocha, Pedro P; Raviram, Ramya; Fu, Yi; Kim, JungHyun; Luo, Vincent M; Aljoufi, Arafat; Swanzey, Emily; Pasquarella, Alessandra; Balestrini, Alessia; Miraldi, Emily R; Bonneau, Richard; Petrini, John; Schotta, Gunnar; Skok, Jane A. A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination. Cell reports. 2016 Jun 28;16(1):48-55 (2159012)

Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation
Proudhon, Charlotte; Snetkova, Valentina; Raviram, Ramya; Lobry, Camille; Badri, Sana; Jiang, Tingting; Hao, Bingtao; Trimarchi, Thomas; Kluger, Yuval; Aifantis, Iannis; Bonneau, Richard; Skok, Jane A. Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation. Cell reports. 2016 Jun 07;15(10):2159-2169 (2125032)