Samuel Sigal

Biosketch / Results /

Samuel Sigal, M.D.

Associate Professor; Co-Dir Transplant Hepatology; Clinical Director Hepatology
Departments of Medicine (Gastro Div) and Surgery (Fac)

Clinical Addresses

530 First Avenue
New York, NY 10016
Hours: Mon. 9 - 5; Tue. 9 - 5; Wed. 9 - 5; Thu. 9 - 5; Fri. 9 - 5
Handicap Access: yes
Phone: 212-263-3643
Fax: 212-263-3751


Additional Clinical Addresses

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Medical Specialties

Gastroenterology, Hepatology

Medical Expertise

Cirrhosis, Hepatitis C, Liver Cancer, Hepatic Encephalopathy, Hepatitis B, Hepatology, Hepatitis, Hepatorenal Syndrome, Bacterial Overgrowth, Liver Disease

Clinical Responsibilities

Dr. Samuel H. Sigal is Associate Professor of Medicine and Surgery at the NYU School of Medicine, and Clinical Director of Hepatology in the Division of Gastroenterology and Co-Director of Transplant Hepatology in the Department of Surgery at Tisch Hospital, NYU Langone Medical Center

Board certified in both Gastroenterology and Transplant Hepatology, Dr. Sigal provides state-of-the-art care in the prevention, diagnosis, and treatment of liver diseases, including chronic liver disease, hepatitis B and C, cirrhosis, fatty liver disease, and liver cancer. Dr. Sigal is a renowned expert in liver transplantation, and in addressing the complex medical needs of men and women with chronic or serious liver disease.

Dr. Sigal's research interests focus on the treatment of liver disease, such as cirrhosis, hepatitis, hepatorenal syndrome, hepatic encephalopathy, and ascites. He has contributed numerous peer-reviewed manuscripts and book chapters to the Gastroenterology and Hepatology scientific literature.

Selected to the New York Times Magazine's "New York Super Doctors" for the past 5 years (2008-2012), Dr. Sigal is a fellow of the American College of Gatroenterology, and a member of the American Association for the Study of Liver Diseases and the American Gastroenterological Association.

Dr. Sigal received his medical degree from the University of Chicago Pritzker School of Medicine. He served a residency in Pathology and Laboratory Medicine at the University of Pennsylvania, Philadelphia, and in Medicine at St. Luke's Hospital, New York City. He completed his fellowship in Gastroenterology at Albert Einstein College of Medicine, and his fellowship in Liver Diseases at Mount Sinai Hospital, New York City.

Insurance

AETNA HMO, AETNA INDEMNITY, AETNA MEDICARE, AETNA POS, AETNA PPO/EPO, AFFINITY, AFFINITY EXCHANGE- ESSENTIAL, CIGNA EPO/POS, Cigna PPO, EBCBS EPO, EBCBS HLTHY NY, EBCBS HMO, EBCBS INDEMNITY, EBCBS MEDIBLUE, EBCBS PATHWAYS / PATHWAYS ENHANCED, EBCBS POS, EBCBS PPO, FIDELIS CHLD HLTH, FIDELIS EXCHANGE, FIDELIS FAM HLTH, FIDELIS MEDICARE, Fidelis Medicaid, GHI CBP, HEALTHPLUS CHLD HLTH (AMERIGROUP), HEALTHPLUS FAM HLTH (AMERIGROUP), HEALTHPLUS MEDICAID (AMERIGROUP), HEALTHREPUBLIC, HIP ACCESS I, HIP ACCESS II, HIP CHLD HLTH, HIP EPO/PPO, HIP FAM HLTH, HIP HMO, HIP MEDICAID, HIP MEDICARE, HIP POS, LOCAL 1199 PPO, MAGNACARE PPO, METROPLUS CHLD HLTH, METROPLUS EXCHANGE PLANS, METROPLUS FAM HLTH, MULTIPLAN/PHCS PPO, Medicare, MetroPlus Medicaid, NY MEDICAID, NYS EMPIRE PLAN, OSCAR, OXFORD EXCHANGE, OXFORD FREEDOM, Oxford Liberty Oxford Medicare, Tricare, UHC COMMUNITY & STATE PLAN, UHC EPO, UHC HMO, UHC MEDICARE, UHC POS, UHC PPO, UHC TOP TIER, UNITED EXCHANGE- COMPASS, WELLCARE CHLD HLTH, WELLCARE FAM HLTH, WELLCARE MEDICAID, WELLCARE MEDICARE

Insurance Disclaimer: Insurance listed above may not be accepted at all office locations. Please confirm prior to each visit. The information presented here may not be complete or may have changed.

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Board Certification

2005 — Ab Internal Medicine (Gastroenterology)
2006 — Ab Internal Medicine (Transplant Hepatology)

Education

1983 — University of Chicago, Medical Education
1983-1987 — Hospital of the University of Penn. (Pathology/Laboratory), Residency Training
1987-1989 — St. Luke's-Roosevelt Hospital Center (Medicine), Internship
1989-1990 — St. Lukes Roosevelt Hospital (Internal Medicine), Residency Training
1990-1993 — Albert Einstein College of Medicine (Gasteoenterology), Clinical Fellowships
1994-2004 — Mount Sinai Medical Center (Liver Diseases), Clinical Fellowships

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Estimating Liver Perfusion From Free-Breathing Continuously Acquired Dynamic Gadolinium-Ethoxybenzyl-Diethylenetriamine Pentaacetic Acid-Enhanced Acquisition With Compressed Sensing Reconstruction
Chandarana, Hersh; Block, Tobias Kai; Ream, Justin; Mikheev, Artem; Sigal, Samuel H; Otazo, Ricardo; Rusinek, Henry
2014 Oct;:138-145, Investigative radiology
— id: 1316222, year: 2014, vol: , page: 138, stat: Journal Article,

New-onset ascites as a manifestation of virologic relapse in patients with hepatitis C cirrhosis
Chua, Deborah Lim; Hahambis, Thomas; Sigal, Samuel H
2014 ;6:11-14, Hepatic medicine: evidence & research
— id: 867342, year: 2014, vol: 6, page: 11, stat: Journal Article,

Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin
Feld, Jordan J; Kowdley, Kris V; Coakley, Eoin; Sigal, Samuel; Nelson, David R; Crawford, Darrell; Weiland, Ola; Aguilar, Humberto; Xiong, Junyuan; Pilot-Matias, Tami; DaSilva-Tillmann, Barbara; Larsen, Lois; Podsadecki, Thomas; Bernstein, Barry
2014 Apr;370(17):1594-1603, New England journal of medicine
— id: 917882, year: 2014, vol: 370, page: 1594, stat: Journal Article,

The child-turcotte-pugh (CTP) score is best at predicting 6-week mortality in patients with acute variceal hemorrhage (AVH): Analysis of a U.S. Multi-center prospective study
Fortune, B E; Garcia-Tsao, G; Ciarleglio, M; Deng, Y; Fallon, M B; Sigal, S; Chalasani, N P; Lim, J K; Reuben, A; Vargas, H E; Abrams, G; Lewis, M B; Hassanein, T; Trotter, J F; Sanyal, A J; Beavers, K L; Ganger, D; Thuluvath, P J; Grace, N D; Groszmann, R J
2014 October 2014;60:1202A-1202A, Hepatology
— id: 1363062, year: 2014, vol: 60, page: 1202A, stat: Journal Article,

Treatment of gastric varices with partial splenic embolization in a patient with portal vein thrombosis and a myeloproliferative disorder
Gianotti, Robert; Charles, Hearns; Hymes, Kenneth; Chandarana, Hersh; Sigal, Samuel
2014 Oct;20(39):14495-14499, World journal of gastroenterology : WJG
— id: 1316392, year: 2014, vol: 20, page: 14495, stat: Journal Article,

Hyponatremia: A risk factor for early overt encephalopathy after transjugular intrahepatic portosystemic shunt creation
Merola, J; Chaudhary, N; Qian, M; Jow, A; Barboza, K; Charles, H; Teperman, L; Sigal, S
2014 04 Apr 2014;3:359-372, Journal of clinical medicine
— id: 953552, year: 2014, vol: 3, page: 359, stat: Journal Article,

Update on management of patients with overt hepatic encephalopathy
Chacko, Kristina R; Sigal, Samuel H
2013 Aug;41(3):48-59, Hospital practice (1995)
— id: 952092, year: 2013, vol: 41, page: 48, stat: Journal Article,

Tips creation is tolerated by patients with portal vein thrombosis with high meld scores
Merola, J; Chaudhary, N; Jow, A; Charles, H W; Teperman, L; Sigal, S
2013 April 2013;58:S94-S94, Journal of hepatology
— id: 349502, year: 2013, vol: 58, page: S94, stat: Journal Article,

Hyponatremia in hospitalized patients with cirrhosis: Interim data from an observational, prospective, multi-center, global hyponatremia registry
Sigal, S; Amin, A; Chiong, J; Dasta, J; Greenberg, A; Verbalis, J; Chiodo, J; Friend, K
2013 April 2013;58:S104-S104, Journal of hepatology
— id: 349492, year: 2013, vol: 58, page: S104, stat: Journal Article,

Albumin and MELD score predict decompensation in patients with HCV cirrhosis and thrombocytopenia on interferon therapy: analysis from the ENABLE studies
Afdhal, Nezam; Giannini, Edoardo G.; Sigal, Samuel; Gordon, Stuart C.; Everson, Gregory T.; Al-Osaimi, Abdullah M.; Dusheiko, Geoffrey M.; Casanovas, Teresa; Brau, Norbert; Vasey, Sandra Y.; Iyengar, Malini; Forssen, Ulla; Campbell, Fiona M.; Theodore, Dickens
2012 OCT;56 1 1:738A-739A, Hepatology
— id: 210082, year: 2012, vol: 56 1 1, page: 738A, stat: Journal Article,

Improved SVR in a unique cohort of non-cirrhotic thrombocytopenic patients with hepatitis C virus (HCV) treated in the global multicenter ENABLE 1 and 2 trials
Afdhal, Nezam; Giannini, Edoardo G.; Sigal, Samuel; Muir, Andrew J.; Reddy, K. Rajender; Sheen, I-Shyan; Vijayaraghavan, Shanthi; Elkashab, Magdy; Romero-Gomez, Manuel; Dusheiko, Geoffrey; Iyengar, Malini; Vasey, Sandra Y.; Campbell, Fiona M.; Theodore, Dickens
2012 OCT;56 1 1:995A-995A, Hepatology
— id: 210062, year: 2012, vol: 56 1 1, page: 995A, stat: Journal Article,

Predictors of Early Hepatic Encephalopathy in Patients Undergoing Transjugular Intrahepatic Portosystemic Shunt (TIPS)
Jow, Alexander Z.; Chaudhary, Noami; Merola, Jonathan; Barboza, Katherine; Qian, Meng; Charles, Hearns; Sigal, Samuel
2012 OCT;56:933A-934A, Hepatology
— id: 218722, year: 2012, vol: 56, page: 933A, stat: Journal Article,

HYPONATREMIA IN HOSPITALIZED PATIENTS WITH CIRRHOSIS: INTERIM DATA FROM AN OBSERVATIONAL, PROSPECTIVE, MULTI-CENTER, GLOBAL HYPONATREMIA REGISTRY INDICATES THAT HYPONATREMIA IS FREQUENTLY NOT TREATED
Sigal, S.; Amin, A.; Chiong, J.; Dasta, J.; Greenberg, A.; Verbalis, J.; Chase, S.; Friend, K.
2012 APR;56 2 2:S269-S270, Journal of hepatology
— id: 166861, year: 2012, vol: 56 2 2, page: S269, stat: Journal Article,

Hyponatremia in cirrhosis
Sigal, Samuel H
2012 Apr;7 Suppl 4:S14-S17, Journal of hospital medicine
— id: 167427, year: 2012, vol: 7 Suppl 4, page: S14, stat: Journal Article,

Impact of liver transplantation on the survival of patients treated for hepatorenal syndrome type 1
Boyer, Thomas D; Sanyal, Arun J; Garcia-Tsao, Guadalupe; Regenstein, Frederick; Rossaro, Lorenzo; Appenrodt, Beate; Gulberg, Veit; Sigal, Samuel; Bexon, Alice S; Teuber, Peter
2011 Nov;17(11):1328-1332, Liver transplantation
— id: 167447, year: 2011, vol: 17, page: 1328, stat: Journal Article,

Rifaximin treatment in hepatic encephalopathy
Bass, Nathan M; Mullen, Kevin D; Sanyal, Arun; Poordad, Fred; Neff, Guy; Leevy, Carroll B; Sigal, Samuel; Sheikh, Muhammad Y; Beavers, Kimberly; Frederick, Todd; Teperman, Lewis; Hillebrand, Donald; Huang, Shirley; Merchant, Kunal; Shaw, Audrey; Bortey, Enoch; Forbes, William P
2010 Mar;362(12):1071-1081, New England journal of medicine
— id: 167446, year: 2010, vol: 362, page: 1071, stat: Journal Article,

Managing hyponatremia in cirrhosis
Ross, Elizabeth; Sigal, Samuel H
2010 Jul-Aug;5 Suppl 3:S8-17, Journal of hospital medicine
— id: 952082, year: 2010, vol: 5 Suppl 3, page: S8, stat: Journal Article,

Pathophysiologic basis for the medical management of portal hypertension
Poordad, Fred F; Sigal, Samuel H; Brown, Robert S
2009 Feb;10(3):453-467, Expert opinion on pharmacotherapy
— id: 104467, year: 2009, vol: 10, page: 453, stat: Journal Article,

CHRONIC ADMINISTRATION OF RIFAXIMIN FOR THE MAINTENANCE OF REMISSION OF HEPATIC ENCEPHALOPAT
Sanyal, A; Bass, N; Teperman, L; Sigal, S; Hillebrand, D; Merchant, K; Huang, S; Shaw, A; Bortey, E; Forbes, W
2009 JUL ;50(3):S90-S90, Journal of hepatology
— id: 100447, year: 2009, vol: 50, page: S90, stat: Journal Article,

A randomized, prospective, double-blind, placebo-controlled trial of terlipressin for type 1 hepatorenal syndrome
Sanyal, Arun J; Boyer, Thomas; Garcia-Tsao, Guadalupe; Regenstein, Frederick; Rossaro, Lorenzo; Appenrodt, Beate; Blei, Andres; Gulberg, Veit; Sigal, Samuel; Teuber, Peter
2008 May;134(5):1360-1368, Gastroenterology
— id: 79421, year: 2008, vol: 134, page: 1360, stat: Journal Article,

Remission of aseptic inflammatory ascites after nephrectomy of a failed allograft
Wan, David W; Serur, David; Bodenheimer, Henry C Jr; Goldstein, Michael J; Sigal, Samuel H
2008 Sep;52(3):626-626, American journal of kidney diseases
— id: 104468, year: 2008, vol: 52, page: 626, stat: Journal Article,

Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C
McHutchison, John G; Dusheiko, Geoffrey; Shiffman, Mitchell L; Rodriguez-Torres, Maribel; Sigal, Samuel; Bourliere, Marc; Berg, Thomas; Gordon, Stuart C; Campbell, Fiona M; Theodore, Dickens; Blackman, Nicole; Jenkins, Julian; Afdhal, Nezam H
2007 Nov 29;357(22):2227-2236, New England journal of medicine
— id: 104469, year: 2007, vol: 357, page: 2227, stat: Journal Article,

Restricted use of albumin for spontaneous bacterial peritonitis
Sigal, Samuel H; Stanca, Carmen M; Fernandez, Javier; Arroyo, Vicente; Navasa, Miguel
2007 Apr;56(4):597-599, Gut: journal of the British Society of Gastroenterology
— id: 104472, year: 2007, vol: 56, page: 597, stat: Journal Article,

Future therapies for hepatitis C: where do we go from here?
Sigal, Samuel; Jacobson, Ira
2007 Feb;4(2):60-61, Nature clinical practice. Gastroenterology & hepatology
— id: 104473, year: 2007, vol: 4, page: 60, stat: Journal Article,

Remission of aseptic inflammatory ascites after nephrectomy of a failed allograft
Wan, David W; Serur, David; Bodenheimer, Henry C Jr; Goldstein, Michael J; Sigal, Samuel H
2007 Oct;50(4):645-648, American journal of kidney diseases
— id: 104471, year: 2007, vol: 50, page: 645, stat: Journal Article,

Hepatitis B and end-stage liver disease
Weisberg, Ilan S; Brown, Robert S Jr; Sigal, Samuel H
2007 Nov;11(4):2227-2236, Clinics in liver disease
— id: 104470, year: 2007, vol: 11, page: 2227, stat: Journal Article,

Randomized trial of pegylated interferon alpha-2b monotherapy in haemodialysis patients with chronic hepatitis C
Russo, Mark W; Ghalib, Reem; Sigal, Samuel; Joshi, Viren
2006 Feb;21(2):437-443, Nephrology, dialysis, transplantation
— id: 104475, year: 2006, vol: 21, page: 437, stat: Journal Article,

Diabetes mellitus is associated with hepatic encephalopathy in patients with HCV cirrhosis
Sigal, Samuel H; Stanca, Carmen M; Kontorinis, Nickolas; Bodian, Carol; Ryan, Elizabeth
2006 Jul;101(7):1490-1496, American journal of gastroenterology
— id: 104474, year: 2006, vol: 101, page: 1490, stat: Journal Article,

Histopathology and clinical correlates of end-stage hepatitis B cirrhosis: a possible mechanism to explain the response to antiviral therapy
Sigal, Samuel H; Ala, Aftab; Ivanov, Katya; Hossain, Sabera; Bodian, Carol; Schiano, Thomas D; Min, Albert D; Bodenheimer, Henry C Jr; Thung, Swan N
2005 Jan;11(1):82-88, Liver transplantation
— id: 104476, year: 2005, vol: 11, page: 82, stat: Journal Article,

Outcome analysis of cirrhotic patients undergoing chest tube placement
Liu, Lawrence U; Haddadin, Hassan A; Bodian, Carol A; Sigal, Samuel H; Korman, Jessica D; Bodenheimer, Henry C Jr; Schiano, Thomas D
2004 Jul;126(1):142-148, Chest
— id: 104477, year: 2004, vol: 126, page: 142, stat: Journal Article,

Survival and risk of recidivism in methadone-dependent patients undergoing liver transplantation
Liu, Lawrence U; Schiano, Thomas D; Lau, Nancy; O'Rourke, Marian; Min, Albert D; Sigal, Samuel H; Drooker, Martin; Bodenheimer, Henry C Jr
2003 Oct;3(10):1273-1277, American journal of transplantation
— id: 104478, year: 2003, vol: 3, page: 1273, stat: Journal Article,

Hepatic Weber-Christian disease
Wasserman JM; Thung SN; Berman R; Bodenheimer HC Jr; Sigal SH
2001 ;21(1):115-118, Seminars in liver disease
— id: 39487, year: 2001, vol: 21, page: 115, stat: Journal Article,

An antigen reacting with das-1 monoclonal antibody is ontogenically regulated in diverse organs including liver and indicates sharing of developmental mechanisms among cell lineages
Badve, S; Logdberg, L; Sokhi, R; Sigal, S H; Botros, N; Chae, S; Das, K M; Gupta, S
2000 Mar-Apr;68(2):76-86, Pathobiology
— id: 167428, year: 2000, vol: 68, page: 76, stat: Journal Article,

Partial hepatectomy-induced polyploidy attenuates hepatocyte replication and activates cell aging events
Sigal, S H; Rajvanshi, P; Gorla, G R; Sokhi, R P; Saxena, R; Gebhard, D R Jr; Reid, L M; Gupta, S
1999 May;276(5 Pt 1):G1260-G1272, American journal of physiology
— id: 167429, year: 1999, vol: 276, page: G1260, stat: Journal Article,

Evidence for a terminal differentiation process in the rat liver
Sigal, S H; Gupta, S; Gebhard, D F Jr; Holst, P; Neufeld, D; Reid, L M
1995 Jul;59(1):35-42, Differentiation
— id: 167433, year: 1995, vol: 59, page: 35, stat: Journal Article,

Demonstration of differentiation in hepatocyte progenitor cells using dipeptidyl peptidase IV deficient mutant rats
Sigal, S H; Rajvanshi, P; Reid, L M; Gupta, S
1995 ;41(1):39-47, Cellular & molecular biology research
— id: 167435, year: 1995, vol: 41, page: 39, stat: Journal Article,

Characterization and enrichment of fetal rat hepatoblasts by immunoadsorption ("panning") and fluorescence-activated cell sorting
Sigal, S H; Brill, S; Reid, L M; Zvibel, I; Gupta, S; Hixson, D; Faris, R; Holst, P A
1994 Apr;19(4):999-1006, Hepatology
— id: 167436, year: 1994, vol: 19, page: 999, stat: Journal Article,