Robert J Schneider

Biosketch / Results /

Robert J Schneider, Ph.D.

Professor; Albert B. Sabin Professor of Microbiology and Molecular Pathogenesis; Associate Dean for Therapeutics Alliances
Departments of Microbiology (Microbiology ) and Radiation Oncology (Radiation Oncology )

Contact Info

450 East 29th street
Floor 3 Room 305
New York, NY


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1981 — Mt. Sinai School of Medicine, New York, NY, Graduate Education
1981-1985 — Dr. Schneider was a Postdoctoral Research Fellow in the Department of Microbiology at Stony Brook, continued at the Department of Molecular Biology at Princeton University, Princeton. NJ, PostDoctoral Training

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Research Summary

I am an Associate Director of the NYU Cancer Institute, Director of Translational Cancer Research, and Co-director of the Breast Cancer Research Program at NYU School of Medicine. Our research is directed to three major areas: (1) the molecular and genetic understanding of advanced breast cancers and the development of new treatment strategies and therapeutics for advanced breast cancers, focusing particularly on the role of protein synthesis and mTOR kinase regulation; (2) the molecular understanding of gene regulation by ionizing radiation, particularly its ability to regulate protein synthesis and use of this knowledge for development of new cancer treatment strategies; and (3) regulation of the inflammatory response by targeted rapid degradation of inflammatory cytokine mRNAs, and the connection to cancer development and progression.

Research Interests

Breast cancer genetics and molecular biology, Post-transcriptional control of gene expression, role of protein synthesis in cancer development

Research Keywords

breast cancer, inflammatory cytokines, inflammation, translational regulation, gene regulation, mRNA stability

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All data from NYU Health Sciences Library Faculty Bibliography — -


Interleukin-17 enhances immunosuppression by mesenchymal stem cells
Han, X; Yang, Q; Lin, L; Xu, C; Zheng, C; Chen, X; Han, Y; Li, M; Cao, W; Cao, K; Chen, Q; Xu, G; Zhang, Y; Zhang, J; Schneider, R J; Qian, Y; Wang, Y; Brewer, G; Shi, Y
2014 Nov;21(11):1758-1768, Cell death & differentiation
— id: 1298722, year: 2014, vol: 21, page: 1758, stat: Journal Article,

Dual mTORC1/2 inhibition in a preclinical xenograft tumor model of endometrial cancer
Korets, Sharmilee Bansal; Musa, Fernanda; Curtin, John; Blank, Stephanie V; Schneider, Robert J
2014 Feb;132(2):468-473, Gynecologic oncology
— id: 810962, year: 2014, vol: 132, page: 468, stat: Journal Article,

Fibromyxoid pseudotumor of the ligamentum teres treated with fresh osteochondral allograft
McLawhorn, Alexander S; Bansal, Manjula; Swensen, Stephanie; Schneider, Robert; Kelly, Bryan T; Williams, Riley J 3rd; Sink, Ernest L
2014 Apr;43(4):541-546, Skeletal radiology
— id: 837992, year: 2014, vol: 43, page: 541, stat: Journal Article,

Cytokines secreted by macrophages isolated from tumor microenvironment of inflammatory breast cancer patients possess chemotactic properties
Mohamed, Mona M; El-Ghonaimy, Eslam A; Nouh, Mohamed A; Schneider, Robert J; Sloane, Bonnie F; El-Shinawi, Mohamed
2014 Jan;46:138-147, International journal of biochemistry & cell biology
— id: 712292, year: 2014, vol: 46, page: 138, stat: Journal Article,

Physiological networks and disease functions of RNA-binding protein AUF1
Moore, Ashleigh E; Chenette, Devon M; Larkin, Lauren C; Schneider, Robert J
2014 Mar;:549-564, Wiley interdisciplinary reviews. RNA
— id: 895642, year: 2014, vol: , page: 549, stat: Journal Article,

RNA-binding protein AUF1 promotes myogenesis by regulating MEF2C expression levels
Panda, Amaresh C; Abdelmohsen, Kotb; Yoon, Je-Hyun; Martindale, Jennifer L; Yang, Xiaoling; Curtis, Jessica; Mercken, Evi M; Chenette, Devon M; Zhang, Yongqing; Schneider, Robert J; Becker, Kevin G; de Cabo, Rafael; Gorospe, Myriam
2014 Jun;:637-639, Molecular & cellular biology
— id: 1030902, year: 2014, vol: , page: 637, stat: Journal Article,

Phase 2 trial of everolimus and carboplatin combination in patients with triple negative metastatic breast cancer
Singh, JC; Novik, Y; Stein, S; Volm, M; Meyers, M; Smith, J; Omene, C; Speyer, J; Schneider, R; Jhaveri, K; Formenti, S; Kyriakou, V; Joseph, B; Goldberg, JD; Li, X; Adams, S; Tiersten, A
2014 ;16(2):- R32, Breast cancer research
— id: 1059672, year: 2014, vol: 16, page: , stat: Journal Article,

Akt and PI3K-dependent but CREB-independent upregulation of MCAM by endothelin-3 in human melanocytes
Williams, Brittny; Schneider, Robert J; Jamal, Sumayah
2014 Apr;:404-407, Melanoma research
— id: 962552, year: 2014, vol: , page: 404, stat: Journal Article,

Human cytomegalovirus infection enhances NF-kappaB/p65 signaling in inflammatory breast cancer patients
El-Shinawi, Mohamed; Mohamed, Hossam Taha; El-Ghonaimy, Eslam A; Tantawy, Marwa; Younis, Amal; Schneider, Robert J; Mohamed, Mona Mostafa
2013 ;8(2):e55755-e55755 e55755, PLoS one
— id: 556252, year: 2013, vol: 8, page: e55755, stat: Journal Article,

Hyperactivated mTOR and JAK2/STAT3 pathways: Crucial molecular drivers and potential therapeutic targets of inflammatory breast cancer (IBC)
Jhaveri, K L; Teplinsky, E; Arju, R; Giashuddin, S; Sarfraz, Y; Alexander, M; Darvishian, F; Silvera, D; Levine, P H; Hashmi, S; Hoffman, H J; Singh, B; Goldberg, J D; Hochman, T; Valeta, A; Schneider, R
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 451852, year: 2013, vol: 31, page: , stat: Journal Article,

4E-BP restrains eIF4E phosphorylation
Muller, D; Lasfargues, C; Khawand, S; Alard, A; Schneider, R; Bousquet, C; Pyronnet, S; Martineau, Y
2013 July/December 2013;1(2):- Article e25819, Translation
— id: 868152, year: 2013, vol: 1, page: , stat: Journal Article,

Dual mTOR inhibition demonstrates antiproliferative and chemosensitizing effects in chemoresistant high-grade papillary serous ovarian cancer
Musa, F.; Giuroiu, I.; Blank, S.; Korets, S.; Curtin, J.; Schneider, R.
2013 OCT;131(1):278-278, Gynecologic oncology
— id: 627492, year: 2013, vol: 131, page: 278, stat: Journal Article,

Vitronectin-alphavbeta3 Integrin Engagement Directs Hypoxia-Resistant mTOR Activity and Sustained Protein Synthesis Linked to Invasion by Breast Cancer Cells
Pola, Carolina; Formenti, Silvia C; Schneider, Robert J
2013 Jul;73(14):4571-4578, Cancer research
— id: 438812, year: 2013, vol: 73, page: 4571, stat: Journal Article,

Dyskerin depletion increases VEGF mRNA internal ribosome entry site-mediated translation
Rocchi, Laura; Pacilli, Annalisa; Sethi, Rajni; Penzo, Marianna; Schneider, Robert J; Trere, Davide; Brigotti, Maurizio; Montanaro, Lorenzo
2013 Sep;41(17):8308-8318, Nucleic acids research
— id: 542672, year: 2013, vol: 41, page: 8308, stat: Journal Article,

RAD001-carboplatin combination in triple-negative metastatic breast cancer (TNMBC): A phase II trial
Singh, J C; Stein, S; Volm, M; Smith, J A; Adams, S; Meyers, M; Speyer, J L; Novik, Y; Schneider, R; Formenti, S; Muggia, F; Jhaveri, K L; Goldberg, J D; Heese, S; Li, X; Davis, S; Tiersten, A
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 452012, year: 2013, vol: 31, page: , stat: Journal Article,

Anti-tumor effects of Ganoderma lucidum (reishi) in inflammatory breast cancer in in vivo and in vitro models
Suarez-Arroyo, Ivette J; Rosario-Acevedo, Raysa; Aguilar-Perez, Alexandra; Clemente, Pedro L; Cubano, Luis A; Serrano, Juan; Schneider, Robert J; Martinez-Montemayor, Michelle M
2013 ;8(2):e57431-e57431 e57431, PLoS one
— id: 556242, year: 2013, vol: 8, page: e57431, stat: Journal Article,

Pathologic response rate in HER2-positive locally advanced breast cancers treated with neoadjuvant trastuzumab and concurrent paclitaxel/radiotherapy
Adams, S; Hochman, T; Huppert, N; Dhage, S; Checka, C; Singh, B; Speyer, J L; Schneider, R; Goldberg, J D; Formenti, S
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 249962, year: 2012, vol: 30, page: , stat: Journal Article,

Atypical ezrin localization as a marker of locally advanced breast cancer
Arslan, AA; Silvera, D; Arju, R; Giashuddin, S; Belitskaya-Levy, I; Formenti, SC; Schneider, RJ
2012 Mar;:981-988, Breast cancer research & treatment
— id: 162566, year: 2012, vol: , page: 981, stat: Journal Article,

DNA damage and eIF4G1 in breast cancer cells reprogram translation for survival and DNA repair mRNAs
Badura, Michelle; Braunstein, Steve; Zavadil, Jiri; Schneider, Robert J
2012 Nov;109(46):18767-18772, Proceedings of the National Academy of Sciences of the United States of America
— id: 182502, year: 2012, vol: 109, page: 18767, stat: Journal Article,

Interstitial fluid pressure correlates with intravoxel incoherent motion imaging metrics in a mouse mammary carcinoma model
Kim, S; Decarlo, L; Cho, GY; Jensen, JH; Sodickson, DK; Moy, L; Formenti, S; Schneider, RJ; Goldberg, JD; Sigmund, EE
2012 Nov;:787-794, NMR in biomedicine
— id: 160660, year: 2012, vol: , page: 787, stat: Journal Article,

Clustering-Based Method for Developing a Genomic Copy Number Alteration Signature for Predicting the Metastatic Potential of Prostate Cancer
Pearlman, Alexander; Campbell, Christopher; Brooks, Eric; Genshaft, Alex; Shajahan, Shahin; Ittman, Michael; Bova, G Steven; Melamed, Jonathan; Holcomb, Ilona; Schneider, Robert J; Ostrer, Harry
2012 ;2012(2012):873570-873570, Journal of probability & statistics
— id: 1359422, year: 2012, vol: 2012, page: 873570, stat: Journal Article,

mRNA Decay Factor AUF1 Maintains Normal Aging, Telomere Maintenance, and Suppression of Senescence by Activation of Telomerase Transcription
Pont, Adam R; Sadri, Navid; Hsiao, Susan J; Smith, Susan; Schneider, Robert J
2012 Jul;47(1):5-15, Molecular cell
— id: 173022, year: 2012, vol: 47, page: 5, stat: Journal Article,

Targeting mRNA translation to enhance the radiosensitivity of inflammatory breast cancer stem cells
Silvera, D; Connolly, E P; Volta, V; Arju, R; Venuto, T; Schneider, R J
2012 15 Dec 2012;Conference:(35th):-, Cancer research
— id: 452022, year: 2012, vol: Conference:, page: , stat: Journal Article,

Phase II trial of RAD001 plus carboplatin in patients with triple-negative metastatic breast cancer
Singh, J C; Stein, S; Volm, M; Smith, J A; Novik, Y; Speyer, J L; Meyers, M; Adams, S; Omene, C O; Muggia, F; Schneider, R; Formenti, S; Davis, S; Beardslee, B; Tiersten, A
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 249952, year: 2012, vol: 30, page: , stat: Journal Article,

The role of health system factors in delaying final diagnosis and treatment of breast cancer in Mexico City, Mexico
Bright, Kristin; Barghash, Maya; Donach, Martin; de la Barrera, Marcos Gutierrez; Schneider, Robert J; Formenti, Silvia C
2011 Apr;20 Suppl 2:S54-S59, Breast
— id: 130301, year: 2011, vol: 20 Suppl 2, page: S54, stat: Journal Article,

Over-expression of translation initiation factor EIF4G confers robust radioresistance to the cancer stem cell population in inflammatory breast cancer
Connolly E.P.; Silvera D.; Badura M.L.; Venuto T.; Schneider R.J.
2011 ;81(2 SUPPL 1):S85-S85, International journal of radiation oncology biology physics
— id: 150897, year: 2011, vol: 81, page: S85, stat: Journal Article,

TORC1/2 inhibition with concurrent radiation controls inflammatory breast cancer in a preclinical animal model through selective blockade of translation
Connolly E.P.; Silvera D.; Venuto T.; Sawai A.; Schneider R.J.
2011 ;81(2 SUPPL 1):S751-S751, International journal of radiation oncology biology physics
— id: 150890, year: 2011, vol: 81, page: S751, stat: Journal Article,

Targeting the mTOR/4E-BP Pathway in Endometrial Cancer
Korets, Sharmilee Bansal; Czok, Sarah; Blank, Stephanie V; Curtin, John P; Schneider, Robert J
2011 Dec 15;17(24):7518-7528, Clinical cancer research
— id: 147690, year: 2011, vol: 17, page: 7518, stat: Journal Article,

Distinct function of androgen receptor coactivator ARA70alpha and ARA70beta in mammary gland development, and in breast cancer
Wu, Xinyu; Chen, Fei; Sahin, Aysegul; Albarracin, Constance; Pei, Zhiheng; Zou, Xuanyi; Singh, Baljit; Xu, Ruliang; Daniels, Garrett; Li, Yirong; Wei, Jianjun; Blake, Marvin; Schneider, Robert J; Cowin, Pamela; Lee, Peng
2011 Jul;128(2):391-400, Breast cancer research & treatment
— id: 138162, year: 2011, vol: 128, page: 391, stat: Journal Article,

Preoperative concurrent paclitaxel-radiation in locally advanced breast cancer: pathologic response correlates with five-year overall survival
Adams, Sylvia; Chakravarthy, A Bapsi; Donach, Martin; Spicer, Darcy; Lymberis, Stella; Singh, Baljit; Bauer, Joshua A; Hochman, Tsivia; Goldberg, Judith D; Muggia, Franco; Schneider, Robert J; Pietenpol, Jennifer A; Formenti, Silvia C
2010 Dec;124(3):723-732, Breast cancer research & treatment
— id: 114178, year: 2010, vol: 124, page: 723, stat: Journal Article,

Identification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation
Bauer, Joshua A; Chakravarthy, A Bapsi; Rosenbluth, Jennifer M; Mi, Deming; Seeley, Erin H; De Matos Granja-Ingram, Nara; Olivares, Maria G; Kelley, Mark C; Mayer, Ingrid A; Meszoely, Ingrid M; Means-Powell, Julie A; Johnson, Kimberly N; Tsai, Chiaojung Jillian; Ayers, Gregory D; Sanders, Melinda E; Schneider, Robert J; Formenti, Silvia C; Caprioli, Richard M; Pietenpol, Jennifer A
2010 Jan 15;16(2):681-690, Clinical cancer research
— id: 109144, year: 2010, vol: 16, page: 681, stat: Journal Article,

Inflammatory Breast Cancer Radio-resistance and its Cancer Stem Cell Population are Oppositely Controlled by Translation Factor elF4G
Connolly, E. P.; Silvera, D.; Badura, M. L.; Braunstein, S. E.; Formenti, S. C.; Schneider, R. J.
2010 OCT 13 ;78(3):S221-S221, International journal of radiation oncology biology physics
— id: 114017, year: 2010, vol: 78, page: S221, stat: Journal Article,

Low-dose radiation augments vasculogenesis signaling through HIF-1-dependent and -independent SDF-1 induction
Lerman, Oren Z; Greives, Matthew R; Singh, Sunil P; Thanik, Vishal D; Chang, Christopher C; Seiser, Natalie; Brown, Daniel J; Knobel, Denis; Schneider, Robert J; Formenti, Silvia C; Saadeh, Pierre B; Levine, Jamie P
2010 Nov 4;116(18):3669-3676, Blood
— id: 138185, year: 2010, vol: 116, page: 3669, stat: Journal Article,

Androgen receptor coactivator p44/Mep50 in breast cancer growth and invasion
Peng, Yi; Li, Yirong; Gellert, Lan Lin; Zou, Xuanyi; Wang, Jun; Singh, Baljit; Xu, Ruliang; Chiriboga, Luis; Daniels, Garrett; Pan, Ruimin; Zhang, David Y; Garabedian, Michael J; Schneider, Robert J; Wang, Zhengxin; Lee, Peng
2010 Dec;14(12):2780-2789, Journal of cellular & molecular medicine
— id: 138376, year: 2010, vol: 14, page: 2780, stat: Journal Article,

Mitotic raptor promotes mTORC1 activity, G(2)/M cell cycle progression, and internal ribosome entry site-mediated mRNA translation
Ramirez-Valle, Francisco; Badura, Michelle L; Braunstein, Steve; Narasimhan, Manisha; Schneider, Robert J
2010 Jul;30(13):3151-3164, Molecular & cellular biology
— id: 110095, year: 2010, vol: 30, page: 3151, stat: Journal Article,

AUF1 is involved in splenic follicular B cell maintenance
Sadri, Navid; Lu, Jin-Yu; Badura, Michelle L; Schneider, Robert J
2010 ;11:1-1, BMC immunology
— id: 107373, year: 2010, vol: 11, page: 1, stat: Journal Article,

Translational control of breast cancer
Schneider R.J.
2010 ;24:?-?, FASEB journal
— id: 138404, year: 2010, vol: 24, page: ?, stat: Journal Article,

Five-year Results of Preoperative Paclitaxel with Concurrent Radiation Therapy in Locally Advanced Breast Cancer: Pathological Response Predicts for Survival
Schneider, R. J.; Formenti, S. C.; Chakravarthy, A.; Adams, S.; Spicer, D.; Lymberis, S.; Goldberg, J. D.; Pietenpol, J. A.
2010 OCT 13 ;78(3):S219-S219, International journal of radiation oncology biology physics
— id: 114016, year: 2010, vol: 78, page: S219, stat: Journal Article,

Translational control in cancer
Silvera, Deborah; Formenti, Silvia C; Schneider, Robert J
2010 Apr;10(4):254-266, Nature reviews. Cancer
— id: 115327, year: 2010, vol: 10, page: 254, stat: Journal Article,

High levels of Hsp90 cochaperone p23 promote tumor progression and poor prognosis in breast cancer by increasing lymph node metastases and drug resistance
Simpson, Natalie E; Lambert, W Marcus; Watkins, Renecia; Giashuddin, Shah; Huang, S Joseph; Oxelmark, Ellinor; Arju, Rezina; Hochman, Tsivia; Goldberg, Judith D; Schneider, Robert J; Reiz, Luiz Fernando Lima; Soares, Fernando Augusto; Logan, Susan K; Garabedian, Michael J
2010 Nov 1;70(21):8446-8456, Cancer research
— id: 114177, year: 2010, vol: 70, page: 8446, stat: Journal Article,

Cutaneous low-dose radiation increases tissue vascularity through upregulation of angiogenic and vasculogenic pathways
Thanik, Vishal D; Chang, Christopher C; Lerman, Oren Z; Greives, Matthew R; Le, Huong; Warren, Stephen M; Schneider, Robert J; Formenti, Sylvia C; Saadeh, Pierre B; Levine, Jamie P
2010 ;47(6):472-480, Journal of vascular research
— id: 113939, year: 2010, vol: 47, page: 472, stat: Journal Article,

Regulation of protein synthesis by ionizing radiation
Braunstein, Steve; Badura, Michelle L; Xi, Qiaoran; Formenti, Silvia C; Schneider, Robert J
2009 Nov;29(21):5645-5656, Molecular & cellular biology
— id: 104346, year: 2009, vol: 29, page: 5645, stat: Journal Article,

Dose-dependent effect of radiation on angiogenic and angiostatic CXC chemokine expression in human endothelial cells
Chang, Christopher C; Lerman, Oren Z; Thanik, Vishal D; Scharf, Carrie L; Greives, Matthew R; Schneider, Robert J; Formenti, Sylvia C; Saadeh, Pierre B; Warren, Stephen M; Levine, Jamie P
2009 Dec;48(3):295-302, Cytokine
— id: 104228, year: 2009, vol: 48, page: 295, stat: Journal Article,

The regulation of protein synthesis in cancer
Cuesta, Rafael; Gupta, Malavika; Schneider, Robert J
2009 ;90:255-292, Progress in molecular biology & translational science
— id: 132875, year: 2009, vol: 90, page: 255, stat: Journal Article,

Similar regulation of human inducible nitric-oxide synthase expression by different isoforms of the RNA-binding protein AUF1
Pautz, Andrea; Linker, Katrin; Altenhofer, Sebastian; Heil, Sebastian; Schmidt, Nadine; Art, Julia; Knauer, Shirley; Stauber, Roland; Sadri, Navid; Pont, Adam; Schneider, Robert J; Kleinert, Hartmut
2009 Jan 30;284(5):2755-2766, Journal of biological chemistry
— id: 94643, year: 2009, vol: 284, page: 2755, stat: Journal Article,

Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease
Sadri, Navid; Schneider, Robert J
2009 Mar;129(3):657-670, Journal of investigative dermatology
— id: 94644, year: 2009, vol: 129, page: 657, stat: Journal Article,

Essential role for eIF4GI overexpression in the pathogenesis of inflammatory breast cancer
Silvera, Deborah; Arju, Rezina; Darvishian, Farbod; Levine, Paul H; Zolfaghari, Ladan; Goldberg, Judith; Hochman, Tsivia; Formenti, Silvia C; Schneider, Robert J
2009 Jul;11(7):903-908, Nature cell biology
— id: 100610, year: 2009, vol: 11, page: 903, stat: Journal Article,

Inflammatory breast cancer cells are constitutively adapted to hypoxia
Silvera, Deborah; Schneider, Robert J
2009 Oct 1;8(19):3091-3096, Cell cycle
— id: 104721, year: 2009, vol: 8, page: 3091, stat: Journal Article,

Bone disease in thalassemia: a frequent and still unresolved problem
Vogiatzi, Maria G; Macklin, Eric A; Fung, Ellen B; Cheung, Angela M; Vichinsky, Elliot; Olivieri, Nancy; Kirby, Melanie; Kwiatkowski, Janet L; Cunningham, Melody; Holm, Ingrid A; Lane, Joseph; Schneider, Robert; Fleisher, Martin; Grady, Robert W; Peterson, Charles C; Giardina, Patricia J
2009 Mar;24(3):543-557, Journal of bone & mineral research
— id: 350902, year: 2009, vol: 24, page: 543, stat: Journal Article,

Acquisition of stable inducible up-regulation of nuclear factor-kappaB by tumor necrosis factor exposure confers increased radiation resistance without increased transformation in breast cancer cells
Braunstein, Steve; Formenti, Silvia C; Schneider, Robert J
2008 Jan;6(1):78-88, Molecular cancer research
— id: 76463, year: 2008, vol: 6, page: 78, stat: Journal Article,

Glioma-like proliferation within tissues excised as tubers in patients with tuberous sclerosis complex
Fischer, Ingeborg; Cunliffe, Clare; Bollo, Robert J; Weiner, Howard L; Devinsky, Orrin; Ruiz-Tachiquin, Martha-Eugenia; Venuto, Toni; Pearlman, Alexander; Chiriboga, Luis; Schneider, Robert J; Ostrer, Harry; Miller, Douglas C
2008 Jul;116(1):67-77, Acta neuropathologica
— id: 79446, year: 2008, vol: 116, page: 67, stat: Journal Article,

Members of the NuRD chromatin remodeling complex interact with AUF1 in developing cortical neurons
Lee, Cheol; Gyorgy, Andrea; Maric, Dragan; Sadri, Navid; Schneider, Robert J; Barker, Jeffery L; Lawson, Michael; Agoston, Denes V
2008 Dec;18(12):2909-2919, Cerebral cortex
— id: 94645, year: 2008, vol: 18, page: 2909, stat: Journal Article,

Radiation-induced CXCL16 release by breast cancer cells attracts effector T cells
Matsumura, Satoko; Wang, Baomei; Kawashima, Noriko; Braunstein, Steve; Badura, Michelle; Cameron, Thomas O; Babb, James S; Schneider, Robert J; Formenti, Silvia C; Dustin, Michael L; Demaria, Sandra
2008 Sep 1;181(5):3099-3107, Journal of immunology (1950)
— id: 81352, year: 2008, vol: 181, page: 3099, stat: Journal Article,

eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy
Ramirez-Valle, Francisco; Braunstein, Steve; Zavadil, Jiri; Formenti, Silvia C; Schneider, Robert J
2008 Apr 21;181(2):293-307, Journal of cell biology
— id: 79095, year: 2008, vol: 181, page: 293, stat: Journal Article,

Lsm proteins bind and stabilize RNAs containing 5' poly(A) tracts
Bergman, Naomi; Moraes, Karen C M; Anderson, John R; Zaric, Bozidarka; Kambach, Christian; Schneider, Robert J; Wilusz, Carol J; Wilusz, Jeffrey
2007 Sep;14(9):824-831, Nature structural & molecular biology
— id: 94646, year: 2007, vol: 14, page: 824, stat: Journal Article,

A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer
Braunstein, Steve; Karpisheva, Ksenia; Pola, Carolina; Goldberg, Judith; Hochman, Tsivia; Yee, Herman; Cangiarella, Joan; Arju, Rezina; Formenti, Silvia C; Schneider, Robert J
2007 Nov 9;28(3):501-512, Molecular cell
— id: 75671, year: 2007, vol: 28, page: 501, stat: Journal Article,

Exploiting breast cancer cells stress response to ionizing radiation to improve the effectiveness of immunotherapy
Demaria, S; Wang, B; Badura, M; Matsumura, S; Kawashima, N; Cameron, T; Dustin, M; Schneider, RJ; Formenti, SC
2007 JAN ;69(3):S597-S597, International journal of radiation oncology biology physics
— id: 87199, year: 2007, vol: 69, page: S597, stat: Journal Article,

Single-dose radiation stimulates induction of stromal derived factor-1 expression and endothelial cell migration independently of hypoxia activation
Lerman, O; Grieves, M; Levine, J; Schneider, R; Formenti, S
2007 JAN ;69(3):S592-S593, International journal of radiation oncology biology physics
— id: 87197, year: 2007, vol: 69, page: S592, stat: Journal Article,

Vitronectin in the tumor microenvironment promotes breast cancer cell proliferation and elevated protein synthesis despite hypoxia by integrin alpha v beta 3 activation of the mTOR/4E-BP1 pathway
Pola, C; Formenti, SC; Schneider, RJ
2007 DEC ;106(1):S162-S162, Breast cancer research & treatment
— id: 75804, year: 2007, vol: 106, page: S162, stat: Journal Article,

TNF Activates a Conserved Innate Antiviral Response to HBV that Destabilizes Nucleocapsids and Reduces Nuclear Viral DNA
Puro, Robyn; Schneider, Robert J
2007 Jul;81(14):7351-7362, Journal of virology
— id: 72042, year: 2007, vol: 81, page: 7351, stat: Journal Article,

Elevated levels of translation initiation factor eIF4G suppresses Radiation(IR)-induced autophagy and cell death
Schneider, RJ; Braunstein, S; Badura, M; Formenti, SC
2007 JAN ;69(3):S593-S593, International journal of radiation oncology biology physics
— id: 87198, year: 2007, vol: 69, page: S593, stat: Journal Article,

Inflammatory breast cancer pathogenesis is mediated in significant part by translation initiation factor eIF4G amplification and unorthodox protein synthesis
Silvera, D; Arju, R; Darvishian, F; Levine, PH; Formenli, SC; Schneider, RJ
2007 DEC ;106(1):S18-S18, Breast cancer research & treatment
— id: 75798, year: 2007, vol: 106, page: S18, stat: Journal Article,

Radiotherapy treatment of early-stage prostate cancer with IMRT and protons: a treatment planning comparison
Trofimov, Alexei; Nguyen, Paul L; Coen, John J; Doppke, Karen P; Schneider, Robert J; Adams, Judith A; Bortfeld, Thomas R; Zietman, Anthony L; Delaney, Thomas F; Shipley, William U
2007 Oct 1;69(2):444-453, International journal of radiation oncology biology physics
— id: 94647, year: 2007, vol: 69, page: 444, stat: Journal Article,

Transforming growth factor-beta and microRNA:mRNA regulatory networks in epithelial plasticity
Zavadil, Jiri; Narasimhan, Manisha; Blumenberg, Miroslav; Schneider, Robert J
2007 ;185(1-3):157-161, Cells tissues organs
— id: 73003, year: 2007, vol: 185, page: 157, stat: Journal Article,

Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication
Bouchard, Michael J; Wang, Lihua; Schneider, Robert J
2006 May;80(9):4406-4414, Journal of virology
— id: 72045, year: 2006, vol: 80, page: 4406, stat: Journal Article,

Ionizing radiation regulates protein synthesis through two novel ATM-independent and ATM-dependent pathways involving mTOR and translation regulator, 4E-BP1
Braunstein, S; Badura, M; Xi, Q; Formenti, SC; Schneider, RJ
2006 FEB ;66(3):S71-S71, International journal of radiation oncology biology physics
— id: 70752, year: 2006, vol: 66, page: S71, stat: Journal Article,

Inhibition of Cap-initiation complexes linked to a novel mechanism of eIF4G depletion in acute myocardial ischemia
Connolly, E P; Thuillier, V; Rouy, D; Bouetard, G; Schneider, R J
2006 Sep;13(9):1586-1594, Cell death & differentiation
— id: 72046, year: 2006, vol: 13, page: 1586, stat: Journal Article,

Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells
Connolly, Eileen; Braunstein, Steve; Formenti, Silvia; Schneider, Robert J
2006 May;26(10):3955-3965, Molecular & cellular biology
— id: 64480, year: 2006, vol: 26, page: 3955, stat: Journal Article,

14-3-3sigma is a p37 AUF1-binding protein that facilitates AUF1 transport and AU-rich mRNA decay
He, Cheng; Schneider, Robert
2006 Aug 23;25(16):3823-3831, EMBO journal
— id: 68985, year: 2006, vol: 25, page: 3823, stat: Journal Article,

A translationally controlled angiogenic switch in locally advanced breast cancer
Karpisheva, K; Braunstein, S; Goldberg, J; Singh, B; Pola, C; Formenti, SC; Schneider, RJ
2006 FEB ;100(2):S11-S11, Breast cancer research & treatment
— id: 71005, year: 2006, vol: 100, page: S11, stat: Journal Article,

MTOR/4E-BP1 pathway is a translational regulator of prostate cancer progression
Karpisheva, KV; Xi, QR; Braunstein, S; Melamed, J; Goldberg, J; Schneider, R
2006 MAR 6 ;20(4):A109-A109, FASEB journal
— id: 63857, year: 2006, vol: 20, page: A109, stat: Journal Article,

Assembly of AUF1 with eIF4G-poly(A) binding protein complex suggests a translation function in AU-rich mRNA decay
Lu, Jin-Yu; Bergman, Naomi; Sadri, Navid; Schneider, Robert J
2006 May;12(5):883-893, RNA
— id: 64460, year: 2006, vol: 12, page: 883, stat: Journal Article,

Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs
Lu, Jin-Yu; Sadri, Navid; Schneider, Robert J
2006 Nov 15;20(22):3174-3184, Genes & development
— id: 69602, year: 2006, vol: 20, page: 3174, stat: Journal Article,

The cochaperone p23 differentially regulates estrogen receptor target genes and promotes tumor cell adhesion and invasion
Oxelmark, Ellinor; Roth, Jennifer M; Brooks, Peter C; Braunstein, Steven E; Schneider, Robert J; Garabedian, Michael J
2006 Jul;26(14):5205-5213, Molecular & cellular biology
— id: 67389, year: 2006, vol: 26, page: 5205, stat: Journal Article,

Over-expression of initiation factor eIF4G typifies inflammatory breast cancer and is crucial for tumor growth, VEGF expression and angiogenesis
Silvera, D; Formenti, SC; Schneider, RJ
2006 FEB ;100(2):S168-S168, Breast cancer research & treatment
— id: 71007, year: 2006, vol: 100, page: S168, stat: Journal Article,

CXCR6 and CXCL16 are expressed by breast cancer cells and may play a dual role in tumor progression
Wang, B; Badura, M; He, C; Cameron, T; Dustin, M; Formenti, SC; Schneider, RJ; Demaria, S
2006 FEB ;100(2):S299-S299, Breast cancer research & treatment
— id: 71013, year: 2006, vol: 100, page: S299, stat: Journal Article,

Childhood abuse and intake severity in alcohol disorder patients
Zlotnick, Caron; Johnson, Dawn M; Stout, Robert L; Zywiak, William H; Johnson, Jennifer E; Schneider, Robert J
2006 Dec;19(6):949-959, Journal of traumatic stress
— id: 72044, year: 2006, vol: 19, page: 949, stat: Journal Article,

Ethical, legal, and social issues related to genomics and cancer research: the impending crisis
Ellerin, Bruce E; Schneider, Robert J; Stern, Arnold; Toniolo, Paolo G; Formenti, Silvia C
2005 Nov;2(11):919-926, Journal of the American College of Radiology : JACR
— id: 72043, year: 2005, vol: 2, page: 919, stat: Journal Article,

Intra- and interfractional patient motion for a variety of immobilization devices
Engelsman, Martijn; Rosenthal, Stanley J; Michaud, Susan L; Adams, Judith A; Schneider, Robert J; Bradley, Stephen G; Flanz, Jacob B; Kooy, Hanne M
2005 Nov;32(11):3468-3474, Medical physics
— id: 72047, year: 2005, vol: 32, page: 3468, stat: Journal Article,

Overexpression of a critical target of rapamycin, translation regulatory protein 4E-BP1, is largely restricted to locally advanced breast and prostrate cancers and is lost with tumor invasiveness
Schneider, Robert J.; Kharpasheva, Ksen; Formenti, Silvia; Braunstein, Steven; Connolly, Eileen
2004 ;45(6):1158-1159, Proceedings (American Association for Cancer Research)
— id: 109232, year: 2004, vol: 45, page: 1158, stat: Journal Article,

An accident waiting to happen: a spatial approach to proactive pedestrian planning
Schneider, Robert J; Ryznar, Rhonda M; Khattak, Asad J
2004 Mar;36(2):193-211, Accident analysis & prevention
— id: 556322, year: 2004, vol: 36, page: 193, stat: Journal Article,

Alcohol relapses associated with September 11, 2001: a case report
Zywiak, William H; Stout, Robert L; Trefry, Winston B; LaGrutta, Joy E; Lawson, Constance C; Khan, Nazia; Swift, Robert M; Schneider, Robert J
2003 Jun;24(2):123-128, Substance abuse
— id: 556332, year: 2003, vol: 24, page: 123, stat: Journal Article,

Hepatitis B Virus HBx Protein Activation of Cyclin A-Cyclin-Dependent Kinase 2 Complexes and G(1) Transit via a Src Kinase Pathway
Bouchard M; Giannakopoulos S; Wang EH; Tanese N; Schneider RJ
2001 May;75(9):4247-4257, Journal of virology
— id: 19695, year: 2001, vol: 75, page: 4247, stat: Journal Article,

Calcium signaling by HBx protein in hepatitis B virus DNA replication
Bouchard, M J; Wang, L H; Schneider, R J
2001 Dec 14;294(5550):2376-2378, Science
— id: 133548, year: 2001, vol: 294, page: 2376, stat: Journal Article,

Hepatitis B virus
Schneider RJ; Ganem D
Fields' virology Philadelphia : Lippincott Williams & Wilkins, 2001,
— id: 2603, year: 2001, vol: , page: ?, stat: Chapter,

Hepatitis B virus
Schneider RJ; Ganem D
Fundamental virology Philadelphia : Lippincott Williams & Wilkins, 2001,
— id: 2604, year: 2001, vol: , page: ?, stat: Chapter,

New ways of initiating translation in eukaryotes
Schneider, R; Agol, V I; Andino, R; Bayard, F; Cavener, D R; Chappell, S A; Chen, J J; Darlix, J L; Dasgupta, A; Donze, O; Duncan, R; Elroy-Stein, O; Farabaugh, P J; Filipowicz, W; Gale, M Jr; Gehrke, L; Goldman, E; Groner, Y; Harford, J B; Hatzglou, M; He, B; Hellen, C U; Hentze, M W; Hershey, J; Hershey, P; Hohn, T; Holcik, M; Hunter, C P; Igarashi, K; Jackson, R; Jagus, R; Jefferson, L S; Joshi, B; Kaempfer, R; Katze, M; Kaufman, R J; Kiledjian, M; Kimball, S R; Kimchi, A; Kirkegaard, K; Koromilas, A E; Krug, R M; Kruys, V; Lamphear, B J; Lemon, S; Lloyd, R E; Maquat, L E; Martinez-Salas, E; Mathews, M B; Mauro, V P; Miyamoto, S; Mohr, I; Morris, D R; Moss, E G; Nakashima, N; Palmenberg, A; Parkin, N T; Pe'ery, T; Pelletier, J; Peltz, S; Pestova, T V; Pilipenko, E V; Prats, A C; Racaniello, V; Read, G S; Rhoads, R E; Richter, J D; Rivera-Pomar, R; Rouault, T; Sachs, A; Sarnow, P; Scheper, G C; Schiff, L; Schoenberg, D R; Semler, B L; Siddiqui, A; Skern, T; Sonenberg, N; Sossin, W; Standart, N; Tahara, S M; Thomas, A A; Toulme, J J; Wilusz, J; Wimmer, E; Witherell, G; Wormington, M
2001 Dec;21(23):8238-8246, Molecular & cellular biology
— id: 1182252, year: 2001, vol: 21, page: 8238, stat: Journal Article,

Calcium-induced stabilization of AU-rich short-lived mRNAs is a common default response
Klein N; Curatola AM; Schneider RJ
1999 ;7(4-6):357-365, Gene expression
— id: 6173, year: 1999, vol: 7, page: 357, stat: Journal Article,

Expression of glutamate receptor-binding PDZ proteins from adenovirus vectors in the CNS in vitro and in vivo
Akaneya, Y.; States, B.; Khatri, L.; Schneider, R.; Ziff, E. B.
1998 ;24(1-2):571-571, Abstracts (Society for Neuroscience)
— id: 92645, year: 1998, vol: 24, page: 571, stat: Journal Article,

Hepatitis B virus HBx protein induces transcription factor AP-1 by activation of extracellular signal-regulated and c-Jun N-terminal mitogen-activated protein kinases
Benn J; Su F; Doria M; Schneider RJ
1996 Aug;70(8):4978-4985, Journal of virology
— id: 6980, year: 1996, vol: 70, page: 4978, stat: Journal Article,

Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation
Feigenblum D; Schneider RJ
1996 Oct;16(10):5450-5457, Molecular & cellular biology
— id: 7069, year: 1996, vol: 16, page: 5450, stat: Journal Article,

Hepatitis B virus HBx protein activates transcription factor NF-kappaB by acting on multiple cytoplasmic inhibitors of rel-related proteins
Su F; Schneider RJ
1996 Jul;70(7):4558-4566, Journal of virology
— id: 8015, year: 1996, vol: 70, page: 4558, stat: Journal Article,

Selective translation initiation by ribosome jumping in adenovirus-infected and heat-shocked cells
Yueh A; Schneider RJ
1996 Jun 15;10(12):1557-1567, Genes & development
— id: 8018, year: 1996, vol: 10, page: 1557, stat: Journal Article,

1995 JAN ;72(1):A128-A128, Laboratory investigation
— id: 87437, year: 1995, vol: 72, page: A128, stat: Journal Article,

Rapid degradation of AU-rich element (ARE) mRNAs is activated by ribosome transit and blocked by secondary structure at any position 5' to the ARE
Curatola AM; Nadal MS; Schneider RJ
1995 Nov;15(11):6331-6340, Molecular & cellular biology
— id: 7922, year: 1995, vol: 15, page: 6331, stat: Journal Article,

The hepatitis B virus X-gene product trans-activates both RNA polymerase II and III promoters
Aufiero, B; Schneider, R J
1990 Feb;9(2):497-504, EMBO journal
— id: 582312, year: 1990, vol: 9, page: 497, stat: Journal Article,

1987 ;13(2):1295-1295, Abstracts (Society for Neuroscience)
— id: 92467, year: 1987, vol: 13, page: 1295, stat: Journal Article,