Ann Marie Schmidt, M.D.

Mechanisms of islet amyloidosis toxicity in type 2 diabetes
Abedini, Andisheh; Schmidt, Ann Marie
2013 Apr;587(8):1119-1127, FEBS letters
— id: 287162, year: 2013, vol: 587, page: 1119, stat: Journal Article,

Alterations in ventricular K(ATP) channel properties during aging
Bao, Li; Taskin, Eylem; Foster, Monique; Ray, Beevash; Rosario, Rosa; Ananthakrishnan, Radha; Howlett, Susan E; Schmidt, Ann M; Ramasamy, Ravichandran; Coetzee, William A
2013 Feb;12(1):167-176, Aging Cell
— id: 213602, year: 2013, vol: 12, page: 167, stat: Journal Article,

RAGE Mediates LPA Induced Pulmonary Inflammation
Cho, SJ; Kwon, S; Naveed, B; Schenck, E; Tsukiji, J; Schmidt, AM; Prezant, DJ; Rom, WN; Weiden, M; Nolan, A
2013 ;187:A3787-A3787, American journal of respiratory & critical care medicine
— id: 291382, year: 2013, vol: 187, page: A3787, stat: Journal Article,

RAGE Deficiency Improves Postinjury Sciatic Nerve Regeneration in Type 1 Diabetic Mice
Juranek, Judyta K; Geddis, Matthew S; Song, Fei; Zhang, Jinghua; Garcia, Jose; Rosario, Rosa; Yan, Shi Fang; Brannagan, Thomas H; Schmidt, Ann Marie
2013 Mar;62(3):931-943, Diabetes
— id: 250702, year: 2013, vol: 62, page: 931, stat: Journal Article,

Macrophages: much more than big eaters!
Schmidt, Ann Marie
2013 Jun;33(6):1118-1119, Arteriosclerosis, thrombosis, & vascular biology
— id: 346522, year: 2013, vol: 33, page: 1118, stat: Journal Article,

The molecular basis of islet amyloid induced cell death
Abedini, Andisheh; Plesner, Annette; Cao, Ping; Zhang, Jinghua; Meng, Fanling Meng; Middleton, Chris; Song, Fei; Zanni, Martin; Verchere, C. Bruce; Raleigh, Daniel; Schmidt, Ann Marie
2012 AUG;21 1 1(SI):204-204, Protein science
— id: 175797, year: 2012, vol: 21 1 1, page: 204, stat: Journal Article,

Diabetes and oral disease: implications for health professionals
Albert, DA; Ward, A; Allweiss, P; Graves, DT; Knowler, WC; Kunzel, C; Leibel, RL; Novak, KF; Oates, TW; Papapanou, PN; Schmidt, AM; Taylor, GW; Lamster, IB; Lalla, E
2012 Mar;:1-15, Annals of the New York Academy of Sciences
— id: 161191, year: 2012, vol: , page: 1, stat: Journal Article,

S100P-Derived RAGE Antagonistic Peptide Reduces Tumor Growth and Metastasis
Arumugam, Thiruvengadam; Ramachandran, Vijaya; Gomez, Sobeyda B; Schmidt, Ann M; Logsdon, Craig D
2012 Aug;18(16):4356-4364, Clinical cancer research
— id: 174390, year: 2012, vol: 18, page: 4356, stat: Journal Article,

Toxic intermediates in islet amyloid formation: Analysis of IAPP mutants reveals a correlation between lag time and toxicity
Cao, Ping; Abedini, Andisheh; Plesner, Annette; Schmidt, Ann Marie; Raleigh, Daniel
2012 AUG;21 1 1(SI):104-105, Protein science
— id: 175801, year: 2012, vol: 21 1 1, page: 104, stat: Journal Article,

Sensitivity of amyloid formation by human islet amyloid polypeptide to mutations at residue 20
Cao, Ping; Tu, Ling-Hsien; Abedini, Andisheh; Levsh, Olesya; Akter, Rehana; Patsalo, Vadim; Schmidt, Ann Marie; Raleigh, Daniel P
2012 Aug;421(2-3):282-295, Journal of molecular biology
— id: 174534, year: 2012, vol: 421, page: 282, stat: Journal Article,

RAGE Gene Deletion Inhibits the Development and Progression of Ductal Neoplasia and Prolongs Survival in a Murine Model of Pancreatic Cancer
Dinorcia J; Lee MK; Moroziewicz DN; Winner M; Suman P; Bao F; Remotti HE; Zou YS; Yan SF; Qiu W; Su GH; Schmidt AM; Allendorf JD
2012 Jan;16(1):104-12; discussion 112, Journal of gastrointestinal surgery
— id: 140586, year: 2012, vol: 16, page: 104, stat: Journal Article,

RAGE mediates vascular injury and inflammation after global cerebral ischemia
Kamide, Tomoya; Kitao, Yasuko; Takeichi, Toshiaki; Okada, Akiko; Mohri, Hiromi; Schmidt, Ann Marie; Kawano, Takayuki; Munesue, Seiichi; Yamamoto, Yasuhiko; Yamamoto, Hiroshi; Hamada, Jun-ichiro; Hori, Osamu
2012 Feb;60(3):220-228, Neurochemistry international
— id: 164277, year: 2012, vol: 60, page: 220, stat: Journal Article,

Rational design of potent domain antibody inhibitors of amyloid fibril assembly
Ladiwala, Ali Reza A; Bhattacharya, Moumita; Perchiacca, Joseph M; Cao, Ping; Raleigh, Daniel P; Abedini, Andisheh; Schmidt, Ann Marie; Varkey, Jobin; Langen, Ralf; Tessier, Peter M
2012 Dec;109(49):19965-19970, Proceedings of the National Academy of Sciences of the United States of America
— id: 205512, year: 2012, vol: 109, page: 19965, stat: Journal Article,

Signal transduction in receptor for advanced glycation end products (RAGE). SOLUTION STRUCTURE OF C-TERMINAL RAGE (ctRAGE) AND ITS BINDING TO mDia1 (vol 287, pg 5133, 2012)
Rai, Vivek; Maldonado, Andres Y.; Burz, David S.; Reverdatto, Sergey; Yan, Shi Fang; Schmidt, Ann Marie; Shekhtman, Alexander
2012 MAR 30;287(14):11283-11283, Journal of biological chemistry
— id: 166672, year: 2012, vol: 287, page: 11283, stat: Journal Article,

Signal Transduction in Receptor for Advanced Glycation End Products (RAGE): SOLUTION STRUCTURE OF C-TERMINAL RAGE (ctRAGE) AND ITS BINDING TO mDia1
Rai, Vivek; Maldonado, Andres Y; Burz, David S; Reverdatto, Sergey; Schmidt, Ann Marie; Shekhtman, Alexander
2012 Feb;287(7):5133-5144, Journal of biological chemistry
— id: 157474, year: 2012, vol: 287, page: 5133, stat: Journal Article,

Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling
Rai, Vivek; Toure, Fatouma; Chitayat, Seth; Pei, Renjun; Song, Fei; Li, Qing; Zhang, Jinghua; Rosario, Rosa; Ramasamy, Ravichandran; Chazin, Walter J; Schmidt, Ann Marie
2012 Dec;209(13):2339-2350, Journal of experimental medicine
— id: 203922, year: 2012, vol: 209, page: 2339, stat: Journal Article,

Islet amyloid: From fundamental biophysics to mechanisms of cytotoxicity
Raleigh, Daniel; Abedini, Andisheh; Cao, Ping; Marek, Peter; Meng, Fanling; Middleton, Chris; Patsalo, Vadim; Plesner, Annette; Schmidt, Ann Marie; Tu, Ling-Hsien; Verchere, C. Bruce; Wang, Hui; Zanni, Marty
2012 AUG;21 1 1(SI):66-66, Protein science
— id: 175798, year: 2012, vol: 21 1 1, page: 66, stat: Journal Article,

Advanced glycation endproducts: from precursors to RAGE: round and round we go
Ramasamy R; Yan SF; Schmidt AM
2012 Apr;42(4):1151-1161, Amino acids
— id: 138340, year: 2012, vol: 42, page: 1151, stat: Journal Article,

Receptor for Advanced Glycation End Products (RAGE) and Implications for the Pathophysiology of Heart Failure
Ramasamy, Ravichandran; Schmidt, Ann Marie
2012 Jun;9(2):107-116, Current heart failure reports
— id: 166791, year: 2012, vol: 9, page: 107, stat: Journal Article,

The diverse ligand repertoire of the receptor for advanced glycation endproducts and pathways to the complications of diabetes
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2012 Nov;57(5-6):160-167, Vascular pharmacology
— id: 178279, year: 2012, vol: 57, page: 160, stat: Journal Article,

Insulin resistance and metabolic syndrome: mechanisms and consequences
Schmidt, Ann Marie
2012 Aug;32(8):1753-1753, Arteriosclerosis, thrombosis, & vascular biology
— id: 174080, year: 2012, vol: 32, page: 1753, stat: Journal Article,

Glycation and insulin resistance: novel mechanisms and unique targets?
Song, Fei; Schmidt, Ann Marie
2012 Aug;32(8):1760-1765, Arteriosclerosis, thrombosis, & vascular biology
— id: 174081, year: 2012, vol: 32, page: 1760, stat: Journal Article,

Quantifying course of RAGE expression after myocardial reperfusion injury
Tekabe, Y; Luma, J; Li, Q; Ramasamy, R; Schmidt, A M; Johnson, L
2012 February 2012;14:S825-S825, Molecular Imaging & Biology
— id: 171163, year: 2012, vol: 14, page: S825, stat: Journal Article,

Imaging of receptors for advanced glycation end products in experimental myocardial ischemia and reperfusion injury
Tekabe, Yared; Luma, Joane; Li, Qing; Schmidt, Ann Marie; Ramasamy, Ravichandran; Johnson, Lynne L
2012 Jan;5(1):59-67, JACC: Cardiovascular Imaging
— id: 155936, year: 2012, vol: 5, page: 59, stat: Journal Article,

Formin mDia1 Mediates Vascular Remodeling via Integration of Oxidative and Signal Transduction Pathways
Toure, Fatouma; Fritz, Gunter; Li, Qing; Rai, Vivek; Daffu, Gurdip; Zou, Yu Shan; Rosario, Rosa; Ramasamy, Ravichandran; Alberts, Arthur S; Yan, Shi Fang; Schmidt, Ann Marie
2012 May;110(10):1279-1293, Circulation research
— id: 166826, year: 2012, vol: 110, page: 1279, stat: Journal Article,

Aldose reductase, oxidative stress and diabetic cardiovascular complications
Vedantham, Srinivasan; Ananthakrishnan, Radha; Schmidt, Ann Marie; Ramasamy, Ravichandran
2012 Sep;10(3):234-240, Cardiovascular & hematological agents in medicinal chemistry
— id: 174070, year: 2012, vol: 10, page: 234, stat: Journal Article,

Opposing roles of RAGE and Myd88 signaling in extensive liver resection
Zeng S; Zhang QY; Huang J; Vedantham S; Rosario R; Ananthakrishnan R; Yan SF; Ramasamy R; Dematteo RP; Emond JC; Friedman RA; Schmidt AM
2012 Feb;26(2):882-893, FASEB journal
— id: 141686, year: 2012, vol: 26, page: 882, stat: Journal Article,

Aldose reductase pathway contributes to vulnerability of aging myocardium to ischemic injury
Ananthakrishnan, Radha; Li, Qing; Gomes, Teodoro; Schmidt, Ann Marie; Ramasamy, Ravichandran
2011 Sep;46(9):762-767, Experimental gerontology
— id: 137436, year: 2011, vol: 46, page: 762, stat: Journal Article,

Advanced glycation end products in diabetic cardiomyopathy: an alternative hypothesis
Hofmann Bowman, Marion A; Fedson, Savitri; Schmidt, Ann Marie
2011 Nov;30(11):1303; discussion 1303-1303; discussion 1304, Journal of heart & lung transplantation
— id: 146223, year: 2011, vol: 30, page: 1303; discussion 1303, stat: Journal Article,

Alternative splicing of RAGE: roles in biology and disease
Kalea, Anastasia Z; Schmidt, Ann Marie; Hudson, Barry I
2011 ;17:2756-2770, Frontiers in biosciences
— id: 141665, year: 2011, vol: 17, page: 2756, stat: Journal Article,

Human vascular endothelial cells: a model system for studying vascular inflammation in diabetes and atherosclerosis
Onat, Duygu; Brillon, David; Colombo, Paolo C; Schmidt, Ann Marie
2011 Jun;11(3):193-202, Current diabetes reports
— id: 134273, year: 2011, vol: 11, page: 193, stat: Journal Article,

Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2011 Dec;1243(1):88-102, Annals of the New York Academy of Sciences
— id: 148734, year: 2011, vol: 1243, page: 88, stat: Journal Article,

Imaging the effect of receptor for advanced glycation endproducts on angiogenic response to hindlimb ischemia in diabetes
Tekabe, Y; Shen, X; Luma, J; Weisenberger, D; Yan, S F; Haubner, R; Schmidt, A M; Johnson, L
2011 2011;1(1):1-9, EJNMMI Research
— id: 174478, year: 2011, vol: 1, page: 1, stat: Journal Article,

Human aldose reductase expression accelerates atherosclerosis in diabetic apolipoprotein e-/- mice
Vedantham, Srinivasan; Noh, Hyelim; Ananthakrishnan, Radha; Son, Ni; Hallam, Kellie; Hu, Yunying; Yu, Shuiquing; Shen, Xiaoping; Rosario, Rosa; Lu, Yan; Ravindranath, Thyyar; Drosatos, Konstantinos; Huggins, Lesley Ann; Schmidt, Ann Marie; Goldberg, Ira J; Ramasamy, Ravichandran
2011 Aug;31(8):1805-1813, Arteriosclerosis, thrombosis, & vascular biology
— id: 135542, year: 2011, vol: 31, page: 1805, stat: Journal Article,

Advanced Glycation End Product Recognition by the Receptor for AGEs
Xue, Jing; Rai, Vivek; Singer, David; Chabierski, Stefan; Xie, Jingjing; Reverdatto, Sergey; Burz, David S; Schmidt, Ann Marie; Hoffmann, Ralf; Shekhtman, Alexander
2011 May 11;19(5):722-732, Structure
— id: 134164, year: 2011, vol: 19, page: 722, stat: Journal Article,

Activation of the ROCK1 branch of the transforming growth factor-beta pathway contributes to RAGE-dependent acceleration of atherosclerosis in diabetic ApoE-null mice
Bu, De-xiu; Rai, Vivek; Shen, Xiaoping; Rosario, Rosa; Lu, Yan; D'Agati, Vivette; Yan, Shi Fang; Friedman, Richard A; Nuglozeh, Edem; Schmidt, Ann Marie
2010 Apr 2;106(6):1040-1051, Circulation research
— id: 140590, year: 2010, vol: 106, page: 1040, stat: Journal Article,

RAGE, glomerulosclerosis and proteinuria: roles in podocytes and endothelial cells
D'Agati, Vivette; Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2010 Jan;21(1):50-56, Trends in endocrinology & metabolism
— id: 130808, year: 2010, vol: 21, page: 50, stat: Journal Article,

RAGE signaling significantly impacts tumorigenesis and hepatic tumor growth in murine models of colorectal carcinoma
DiNorcia, Joseph; Moroziewicz, Dorota N; Ippagunta, Nikalesh; Lee, Minna K; Foster, Mark; Rotterdam, Heidrun Z; Bao, Fei; Zhou, Yu Shan; Yan, Shi Fang; Emond, Jean; Schmidt, Ann Marie; Allendorf, John D
2010 Nov;14(11):1680-1690, Journal of gastrointestinal surgery
— id: 140587, year: 2010, vol: 14, page: 1680, stat: Journal Article,

RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease
Fang, Fang; Lue, Lih-Fen; Yan, Shiqiang; Xu, Hongwei; Luddy, John S; Chen, Doris; Walker, Douglas G; Stern, David M; Yan, Shifang; Schmidt, Ann Marie; Chen, John X; Yan, Shirley ShiDu
2010 Apr;24(4):1043-1055, FASEB journal
— id: 140647, year: 2010, vol: 24, page: 1043, stat: Journal Article,

Aldose reductase and AGE-RAGE pathways: central roles in the pathogenesis of vascular dysfunction in aging rats
Hallam, Kellie McCormick; Li, Qing; Ananthakrishnan, Radha; Kalea, Anastasia; Zou, Yu S; Vedantham, Srinivasan; Schmidt, Ann Marie; Yan, Shi Fang; Ramasamy, Ravichandran
2010 Oct;9(5):776-784, Aging Cell
— id: 130803, year: 2010, vol: 9, page: 776, stat: Journal Article,

Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse
Reiniger, Nina; Lau, Kai; McCalla, Daren; Eby, Bonnie; Cheng, Bin; Lu, Yan; Qu, Wu; Quadri, Nosirudeen; Ananthakrishnan, Radha; Furmansky, Maryana; Rosario, Rosa; Song, Fei; Rai, Vivek; Weinberg, Alan; Friedman, Richard; Ramasamy, Ravichandran; D'Agati, Vivette; Schmidt, Ann Marie
2010 Aug;59(8):2043-2054, Diabetes
— id: 130804, year: 2010, vol: 59, page: 2043, stat: Journal Article,

RAGE modulates hypoxia/reoxygenation injury in adult murine cardiomyocytes via JNK and GSK-3beta signaling pathways
Shang, Linshan; Ananthakrishnan, Radha; Li, Qing; Quadri, Nosirudeen; Abdillahi, Mariane; Zhu, Zhengbin; Qu, Wu; Rosario, Rosa; Toure, Fatouma; Yan, Shi Fang; Schmidt, Ann Marie; Ramasamy, Ravichandran
2010 ;5(4):e10092-e10092, PLoS ONE
— id: 130806, year: 2010, vol: 5, page: e10092, stat: Journal Article,

Advanced glycation end product (AGE)-receptor for AGE (RAGE) signaling and up-regulation of Egr-1 in hypoxic macrophages
Xu, Yunlu; Toure, Fatouma; Qu, Wu; Lin, Lili; Song, Fei; Shen, Xiaoping; Rosario, Rosa; Garcia, Joel; Schmidt, Ann Marie; Yan, Shi-Fang
2010 Jul 23;285(30):23233-23240, Journal of biological chemistry
— id: 140589, year: 2010, vol: 285, page: 23233, stat: Journal Article,

Soluble RAGE: therapy and biomarker in unraveling the RAGE axis in chronic disease and aging
Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2010 May 15;79(10):1379-1386, Biochemical pharmacology
— id: 130805, year: 2010, vol: 79, page: 1379, stat: Journal Article,

The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature
Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2010 Mar 19;106(5):842-853, Circulation research
— id: 130807, year: 2010, vol: 106, page: 842, stat: Journal Article,

Inflammatory stress in primary venous and aortic endothelial cells of type 1 diabetic mice
Bucciarelli, Loredana G; Pollreisz, Andreas; Kebschull, Moritz; Ganda, Anjali; Kalea, Anastasia Z; Hudson, Barry I; Zou, Yu Shan; Lalla, Evanthia; Ramasamy, Ravichandran; Colombo, Paolo C; Schmidt, Ann Marie; Yan, Shi Fang
2009 Oct;6(4):249-261, Diabetes & vascular disease research
— id: 130799, year: 2009, vol: 6, page: 249, stat: Journal Article,

The pattern recognition receptor CD36 is a chondrocyte hypertrophy marker associated with suppression of catabolic responses and promotion of repair responses to inflammatory stimuli
Cecil, Denise L; Appleton, C Thomas G; Polewski, Monika D; Mort, John S; Schmidt, Ann Marie; Bendele, Alison; Beier, Frank; Terkeltaub, Robert
2009 Apr 15;182(8):5024-5031, Journal of immunology
— id: 133754, year: 2009, vol: 182, page: 5024, stat: Journal Article,

Mice deficient in PKCbeta and apolipoprotein E display decreased atherosclerosis
Harja, Evis; Chang, Jong Sun; Lu, Yan; Leitges, Michael; Zou, Yu Shan; Schmidt, Ann Marie; Yan, Shi-Fang
2009 Apr;23(4):1081-1091, FASEB journal
— id: 140591, year: 2009, vol: 23, page: 1081, stat: Journal Article,

Neuronal RAGE expression modulates severity of injury following transient focal cerebral ischemia
Hassid, Benjamin G; Nair, M Nathan; Ducruet, Andrew F; Otten, Marc L; Komotar, Ricardo J; Pinsky, David J; Schmidt, Ann Marie; Yan, Shi Fang; Connolly, E Sander
2009 Feb;16(2):302-306, Journal of clinical neuroscience
— id: 140592, year: 2009, vol: 16, page: 302, stat: Journal Article,

RAGE: therapeutic target and biomarker of the inflammatory response--the evidence mounts
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2009 Sep;86(3):505-512, Journal of leukocyte biology
— id: 130810, year: 2009, vol: 86, page: 505, stat: Journal Article,

Novel role for aldose reductase in mediating acute inflammatory responses in the lung
Ravindranath, Thyyar M; Mong, Phyllus Y; Ananthakrishnan, Radha; Li, Qing; Quadri, Nosirudeen; Schmidt, Ann Marie; Ramasamy, Ravichandran; Wang, Qin
2009 Dec 15;183(12):8128-8137, Journal of immunology
— id: 130809, year: 2009, vol: 183, page: 8128, stat: Journal Article,

Receptor for AGE (RAGE) and its ligands-cast into leading roles in diabetes and the inflammatory response
Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2009 Mar;87(3):235-247, Journal of Molecular Medicine (Berlin)
— id: 130812, year: 2009, vol: 87, page: 235, stat: Journal Article,

The receptor for advanced glycation endproducts (RAGE) and cardiovascular disease
Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2009 ;11:e9-e9, Expert reviews in molecular medicine
— id: 130811, year: 2009, vol: 11, page: e9, stat: Journal Article,

Tempering the wrath of RAGE: an emerging therapeutic strategy against diabetic complications, neurodegeneration, and inflammation
Yan, Shi Fang; Yan, Shi Du; Ramasamy, Ravichandran; Schmidt, Ann Marie
2009 ;41(6):408-422, Annals of medicine (Helsinki)
— id: 130813, year: 2009, vol: 41, page: 408, stat: Journal Article,

Receptor for advanced glycation end product (RAGE)-dependent modulation of early growth response-1 in hepatic ischemia/reperfusion injury
Zeng, Shan; Dun, Hao; Ippagunta, Nikalesh; Rosario, Rosa; Zhang, Qing Y; Lefkowitch, Jay; Yan, Shi F; Schmidt, Ann Marie; Emond, Jean C
2009 May;50(5):929-936, Journal of hepatology
— id: 140646, year: 2009, vol: 50, page: 929, stat: Journal Article,

RAGE modulates myocardial injury consequent to LAD infarction via impact on JNK and STAT signaling in a murine model
Aleshin, Alexey; Ananthakrishnan, Radha; Li, Qing; Rosario, Rosa; Lu, Yan; Qu, Wu; Song, Fei; Bakr, Soliman; Szabolcs, Matthias; D'Agati, Vivette; Liu, Rui; Homma, Shunichi; Schmidt, Ann Marie; Yan, Shi Fang; Ramasamy, Ravichandran
2008 Apr;294(4):H1823-H1832, American journal of physiology. Heart & circulatory physiology
— id: 130818, year: 2008, vol: 294, page: H1823, stat: Journal Article,

RAGE and modulation of ischemic injury in the diabetic myocardium
Bucciarelli, Loredana G; Ananthakrishnan, Radha; Hwang, Yuying C; Kaneko, Michiyo; Song, Fei; Sell, David R; Strauch, Christopher; Monnier, Vincent M; Yan, Shi Fang; Schmidt, Ann Marie; Ramasamy, Ravichandran
2008 Jul;57(7):1941-1951, Diabetes
— id: 130800, year: 2008, vol: 57, page: 1941, stat: Journal Article,

Oxygen deprivation triggers upregulation of early growth response-1 by the receptor for advanced glycation end products
Chang, Jong Sun; Wendt, Thoralf; Qu, Wu; Kong, Linghua; Zou, Yu Shan; Schmidt, Ann Marie; Yan, Shi-Fang
2008 Apr 25;102(8):905-913, Circulation research
— id: 140593, year: 2008, vol: 102, page: 905, stat: Journal Article,

RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis
Guo, Jiancheng; Ananthakrishnan, Radha; Qu, Wu; Lu, Yan; Reiniger, Nina; Zeng, Shan; Ma, Wanchao; Rosario, Rosa; Yan, Shi Fang; Ramasamy, Ravichandran; D'Agati, Vivette; Schmidt, Ann Marie
2008 May;19(5):961-972, Journal of the American Society of Nephrology
— id: 130816, year: 2008, vol: 19, page: 961, stat: Journal Article,

Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice
Harja, Evis; Bu, De-xiu; Hudson, Barry I; Chang, Jong Sun; Shen, Xiaoping; Hallam, Kellie; Kalea, Anastasia Z; Lu, Yan; Rosario, Rosa H; Oruganti, Sai; Nikolla, Zana; Belov, Dmitri; Lalla, Evanthia; Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2008 Jan;118(1):183-194, Journal of clinical investigation
— id: 130821, year: 2008, vol: 118, page: 183, stat: Journal Article,

PKCbeta modulates ischemia-reperfusion injury in the heart
Kong, Linghua; Andrassy, Martin; Chang, Jong Sun; Huang, Chun; Asai, Tomohiro; Szabolcs, Matthias J; Homma, Shunichi; Liu, Rui; Zou, Yu Shan; Leitges, Michael; Yan, Shi Du; Ramasamy, Ravichandran; Schmidt, Ann Marie; Yan, Shi-Fang
2008 Apr;294(4):H1862-H1870, American journal of physiology. Heart & circulatory physiology
— id: 130819, year: 2008, vol: 294, page: H1862, stat: Journal Article,

Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction
Origlia, Nicola; Righi, Massimo; Capsoni, Simona; Cattaneo, Antonino; Fang, Fang; Stern, David M; Chen, John Xi; Schmidt, Ann Marie; Arancio, Ottavio; Yan, Shi Du; Domenici, Luciano
2008 Mar 26;28(13):3521-3530, Journal of neuroscience
— id: 140645, year: 2008, vol: 28, page: 3521, stat: Journal Article,

Receptor for advanced glycation end products: fundamental roles in the inflammatory response: winding the way to the pathogenesis of endothelial dysfunction and atherosclerosis
Ramasamy, Ravichandran; Yan, Shi Fang; Herold, Kevan; Clynes, Raphael; Schmidt, Ann Marie
2008 Apr;1126:7-13, Annals of the New York Academy of Sciences
— id: 130820, year: 2008, vol: 1126, page: 7, stat: Journal Article,

Stopping the primal RAGE reaction in myocardial infarction: capturing adaptive responses to heal the heart?
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2008 Jun 24;117(25):3165-3167, Circulation
— id: 130815, year: 2008, vol: 117, page: 3165, stat: Journal Article,

Blockade of receptor for advanced glycation end product attenuates pulmonary reperfusion injury in mice
Sternberg, David I; Gowda, Ram; Mehra, Divya; Qu, Wu; Weinberg, Alan; Twaddell, William; Sarkar, Joydeep; Wallace, Allison; Hudson, Barry; D'Ovidio, Frank; Arcasoy, Selim; Ramasamy, Ravichandran; D'Armiento, Jeanine; Schmidt, Ann Marie; Sonett, Joshua R
2008 Dec;136(6):1576-1585, Journal of thoracic & cardiovascular surgery
— id: 130814, year: 2008, vol: 136, page: 1576, stat: Journal Article,

Mechanisms of disease: advanced glycation end-products and their receptor in inflammation and diabetes complications
Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2008 May;4(5):285-293, Nature clinical practice. Endocrinology & metabolism
— id: 130817, year: 2008, vol: 4, page: 285, stat: Journal Article,

Receptor for AGE (RAGE): weaving tangled webs within the inflammatory response
Clynes, Raphael; Moser, Bernhard; Yan, Shi Fang; Ramasamy, Ravichandran; Herold, Kevan; Schmidt, Ann Marie
2007 Dec;7(8):743-751, Current molecular medicine
— id: 130822, year: 2007, vol: 7, page: 743, stat: Journal Article,

Receptor for advanced glycation end products (RAGE) in a dash to the rescue: inflammatory signals gone awry in the primal response to stress
Herold, Kevan; Moser, Bernhard; Chen, Yali; Zeng, Shan; Yan, Shi Fang; Ramasamy, Ravichandran; Emond, Jean; Clynes, Raphael; Schmidt, Ann Marie
2007 Aug;82(2):204-212, Journal of leukocyte biology
— id: 130825, year: 2007, vol: 82, page: 204, stat: Journal Article,

Receptor for advanced glycation end products expression on T cells contributes to antigen-specific cellular expansion in vivo
Moser, Bernhard; Desai, Dharmesh D; Downie, Matthew P; Chen, Yali; Yan, Shi Fang; Herold, Kevan; Schmidt, Ann Marie; Clynes, Raphael
2007 Dec 15;179(12):8051-8058, Journal of immunology
— id: 140594, year: 2007, vol: 179, page: 8051, stat: Journal Article,

Arguing for the motion: yes, RAGE is a receptor for advanced glycation endproducts
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2007 Sep;51(9):1111-1115, Molecular nutrition & food research
— id: 130824, year: 2007, vol: 51, page: 1111, stat: Journal Article,

The biology of RAGE and its ligands: uncovering mechanisms at the heart of diabetes and its complications
Yan, Shi Fang; Barile, Gaetano R; D'Agati, Vivette; Du Yan, Shi; Ramasamy, Ravichandran; Schmidt, Ann Marie
2007 Apr;7(2):146-153, Current diabetes reports
— id: 130826, year: 2007, vol: 7, page: 146, stat: Journal Article,

Receptor for Advanced Glycation Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes & aging
Yan, Shi Fang; D'Agati, Vivette; Schmidt, Ann Marie; Ramasamy, Ravichandran
2007 Dec;7(8):699-710, Current molecular medicine
— id: 130823, year: 2007, vol: 7, page: 699, stat: Journal Article,

Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury
Bucciarelli, Loredana G; Kaneko, Michiyo; Ananthakrishnan, Radha; Harja, Evis; Lee, Larisse K; Hwang, Yuying C; Lerner, Shulamit; Bakr, Soliman; Li, Qing; Lu, Yan; Song, Fei; Qu, Wu; Gomez, Teodoro; Zou, Yu Shan; Yan, Shi Fang; Schmidt, Ann Marie; Ramasamy, Ravichandran
2006 Mar 7;113(9):1226-1234, Circulation
— id: 130801, year: 2006, vol: 113, page: 1226, stat: Journal Article,

Blockade of the receptor for advanced glycation end products attenuates acetaminophen-induced hepatotoxicity in mice
Ekong, Udeme; Zeng, Shan; Dun, Hao; Feirt, Nikki; Guo, Jiancheng; Ippagunta, Nikalesh; Guarrera, James V; Lu, Yan; Weinberg, Alan; Qu, Wu; Ramasamy, Ravichandran; Schmidt, Ann Marie; Emond, Jean C
2006 Apr;21(4):682-688, Journal of gastroenterology & hepatology
— id: 130829, year: 2006, vol: 21, page: 682, stat: Journal Article,

Upregulation of RAGE and its ligands in proliferative retinal disease
Pachydaki, Sophia I; Tari, Samir R; Lee, Song Eun; Ma, Wanchao; Tseng, Joseph J; Sosunov, Alexander A; Cataldergirmen, Guellue; Scarmeas, Nikolaos; Caspersen, Casper; Chang, Stanley; Schiff, William M; Schmidt, Ann Marie; Barile, Gaetano R
2006 May;82(5):807-815, Experimental eye research
— id: 161164, year: 2006, vol: 82, page: 807, stat: Journal Article,

Methylglyoxal comes of AGE
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2006 Jan 27;124(2):258-260, Cell
— id: 130830, year: 2006, vol: 124, page: 258, stat: Journal Article,

Sphingosine-1-phosphate: waging a battle in the diabetic blood vessel
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2006 Sep 29;99(7):669-671, Circulation research
— id: 130827, year: 2006, vol: 99, page: 669, stat: Journal Article,

Diabetes, leukoencephalopathy and rage
Toth, Cory; Schmidt, Ann Marie; Tuor, Ursula I; Francis, George; Foniok, Tadeusz; Brussee, Valentine; Kaur, Jaspreet; Yan, Shi Fang; Martinez, Jose A; Barber, Philip A; Buchan, Alastair; Zochodne, Douglas W
2006 Aug;23(2):445-461, Neurobiology of disease
— id: 140598, year: 2006, vol: 23, page: 445, stat: Journal Article,

RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes
Wendt, Thoralf; Harja, Evis; Bucciarelli, Loredana; Qu, Wu; Lu, Yan; Rong, Ling Ling; Jenkins, Daniel G; Stein, Guenther; Schmidt, Ann Marie; Yan, Shi Fang
2006 Mar;185(1):70-77, Atherosclerosis
— id: 140599, year: 2006, vol: 185, page: 70, stat: Journal Article,

The ligand/RAGE axis: lighting the fuse and igniting vascular stress
Yan, Shi Fang; Naka, Yoshifumi; Hudson, Barry I; Herold, Kevan; Yan, Shi Du; Ramasamy, Ravichandran; Schmidt, Ann Marie
2006 May;8(3):232-239, Current atherosclerosis reports
— id: 130828, year: 2006, vol: 8, page: 232, stat: Journal Article,

Receptor for advanced glycation end products and the cardiovascular complications of diabetes and beyond: lessons from AGEing
Yan, Shi Fang; Yan, Shi Du; Herold, Kevan; Ramsamy, Ravichandran; Schmidt, Ann Marie
2006 Sep;35(3):4565-4573, Endocrinology & metabolism clinics of North America
— id: 140597, year: 2006, vol: 35, page: 4565, stat: Journal Article,

Protein kinase C beta/early growth response-1 pathway: a key player in ischemia, atherosclerosis, and restenosis
Yan, Shi-Fang; Harja, Evis; Andrassy, Martin; Fujita, Tomoyuki; Schmidt, Ann Marie
2006 Nov 7;48(9 Suppl 1):A47-A55, Journal of the American College of Cardiology
— id: 140595, year: 2006, vol: 48, page: A47, stat: Journal Article,

Central role of PKCbeta in neointimal expansion triggered by acute arterial injury
Andrassy, Martin; Belov, Dmitry; Harja, Evis; Zou, Yu Shan; Leitges, Michael; Katus, Hugo A; Nawroth, Peter P; Yan, Shi Du; Schmidt, Ann Marie; Yan, Shi-Fang
2005 Mar 4;96(4):476-483, Circulation research
— id: 140602, year: 2005, vol: 96, page: 476, stat: Journal Article,

The RAGE axis in early diabetic retinopathy
Barile, Gaetano R; Pachydaki, Sophia I; Tari, Samir R; Lee, Song E; Donmoyer, Christine M; Ma, Wanchao; Rong, Ling Ling; Buciarelli, Loredana G; Wendt, Thoralf; Horig, Heidi; Hudson, Barry I; Qu, Wu; Weinberg, Alan D; Yan, Shi Fang; Schmidt, Ann Marie
2005 Aug;46(8):2916-2924, Investigative ophthalmology & visual science. IOVS
— id: 140601, year: 2005, vol: 46, page: 2916, stat: Journal Article,

RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-kappaB
Cataldegirmen, Guellue; Zeng, Shan; Feirt, Nikki; Ippagunta, Nikalesh; Dun, Hao; Qu, Wu; Lu, Yan; Rong, Ling Ling; Hofmann, Marion A; Kislinger, Thomas; Pachydaki, Sophia I; Jenkins, Daniel G; Weinberg, Alan; Lefkowitch, Jay; Rogiers, Xavier; Yan, Shi Fang; Schmidt, Ann Marie; Emond, Jean C
2005 Feb 7;201(3):473-484, Journal of experimental medicine
— id: 140603, year: 2005, vol: 201, page: 473, stat: Journal Article,

RAGE and amyloid beta interactions: atomic force microscopy and molecular modeling
Chaney, Michael O; Stine, W Blaine; Kokjohn, Tyler A; Kuo, Yu-Min; Esh, Chera; Rahman, Afroza; Luehrs, Dean C; Schmidt, Ann Marie; Stern, David; Yan, Shi Du; Roher, Alex E
2005 Jun 30;1741(1-2):199-205, Biochimica & biophysica acta
— id: 140644, year: 2005, vol: 1741, page: 199, stat: Journal Article,

The RAGE Gly82Ser polymorphism is not associated with cardiovascular disease in the Framingham offspring study
Hofmann, Marion A; Yang, Qiong; Harja, Evis; Kedia, Prashant; Gregersen, Peter K; Cupples, L Adrienne; Schmidt, Ann Marie; Hudson, Barry I
2005 Oct;182(2):301-305, Atherosclerosis
— id: 93133, year: 2005, vol: 182, page: 301, stat: Journal Article,

Diabetic vascular disease: it's all the RAGE
Hudson, Barry I; Wendt, Thoralf; Bucciarelli, Loredana G; Rong, Ling Ling; Naka, Yoshifumi; Yan, Shi Fang; Schmidt, Ann Marie
2005 Nov-Dec;7(11-12):1588-1600, Antioxidants & Redox Signaling
— id: 140600, year: 2005, vol: 7, page: 1588, stat: Journal Article,

Aldose reductase and AGE-RAGE pathways: key players in myocardial ischemic injury
Kaneko, Michiyo; Bucciarelli, Loredana; Hwang, Yuying C; Lee, Larisee; Yan, Shi Fang; Schmidt, Ann Marie; Ramasamy, Ravichandran
2005 Jun;1043:702-709, Annals of the New York Academy of Sciences
— id: 130802, year: 2005, vol: 1043, page: 702, stat: Journal Article,

Receptor for advanced glycation end products and its ligands: a journey from the complications of diabetes to its pathogenesis
Kim, William; Hudson, Barry I; Moser, Bernhard; Guo, Jiancheng; Rong, Ling Ling; Lu, Yan; Qu, Wu; Lalla, Evanthia; Lerner, Shulamit; Chen, Yali; Yan, Shirley Shi Du; D'Agati, Vivette; Naka, Yoshifumi; Ramasamy, Ravichandran; Herold, Kevan; Yan, Shi Fang; Schmidt, Ann Marie
2005 Jun;1043:553-561, Annals of the New York Academy of Sciences
— id: 130833, year: 2005, vol: 1043, page: 553, stat: Journal Article,

Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation
Ramasamy, Ravichandran; Vannucci, Susan J; Yan, Shirley Shi Du; Herold, Kevan; Yan, Shi Fang; Schmidt, Ann Marie
2005 Jul;15(7):16R-28R, Glycobiology
— id: 130832, year: 2005, vol: 15, page: 16R, stat: Journal Article,

The RAGE axis and endothelial dysfunction: maladaptive roles in the diabetic vasculature and beyond
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2005 Oct;15(7):237-243, Trends in cardiovascular medicine
— id: 130831, year: 2005, vol: 15, page: 237, stat: Journal Article,

RAGE: a journey from the complications of diabetes to disorders of the nervous system - striking a fine balance between injury and repair
Rong, Ling Ling; Gooch, Clifton; Szabolcs, Mattias; Herold, Kevan C; Lalla, Evanthia; Hays, Arthur P; Yan, Shi Fang; Yan, Shirley Shi Du; Schmidt, Ann Marie
2005 ;23(5-6):355-365, Restorative Neurology & Neuroscience
— id: 140604, year: 2005, vol: 23, page: 355, stat: Journal Article,

RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice
Arancio, Ottavio; Zhang, Hui Ping; Chen, Xi; Lin, Chang; Trinchese, Fabrizio; Puzzo, Daniela; Liu, Shumin; Hegde, Ashok; Yan, Shi Fang; Stern, Alan; Luddy, John S; Lue, Lih-Fen; Walker, Douglas G; Roher, Alex; Buttini, Manuel; Mucke, Lennart; Li, Weiying; Schmidt, Ann Marie; Kindy, Mark; Hyslop, Paul A; Stern, David M; Du Yan, Shirley Shi
2004 Oct 13;23(20):4096-4105, EMBO journal
— id: 47799, year: 2004, vol: 23, page: 4096, stat: Journal Article,

Blockade of late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation end products
Chen, Yali; Yan, Shirley ShiDu; Colgan, John; Zhang, Hui-Ping; Luban, Jeremy; Schmidt, Ann Marie; Stern, David; Herold, Kevan C
2004 Jul 15;173(2):1399-1405, Journal of immunology
— id: 140643, year: 2004, vol: 173, page: 1399, stat: Journal Article,

PKCbeta regulates ischemia/reperfusion injury in the lung
Fujita, Tomoyuki; Asai, Tomohiro; Andrassy, Martin; Stern, David M; Pinsky, David J; Zou, Yu Shan; Okada, Morihito; Naka, Yoshifumi; Schmidt, Ann Marie; Yan, Shi-Fang
2004 Jun;113(11):1615-1623, Journal of clinical investigation
— id: 140606, year: 2004, vol: 113, page: 1615, stat: Journal Article,

Early growth response-1 promotes atherogenesis: mice deficient in early growth response-1 and apolipoprotein E display decreased atherosclerosis and vascular inflammation
Harja, Evis; Bucciarelli, Loredana G; Lu, Yan; Stern, David M; Zou, Yu Shan; Schmidt, Ann Marie; Yan, Shi-Fang
2004 Feb 20;94(3):333-339, Circulation research
— id: 140607, year: 2004, vol: 94, page: 333, stat: Journal Article,

Central role for aldose reductase pathway in myocardial ischemic injury
Hwang, Yuying C; Kaneko, Michiyo; Bakr, Soliman; Liao, Hui; Lu, Yan; Lewis, Erin R; Yan, Shidu; Ii, Setsuko; Itakura, Mitsuo; Rui, Liu; Skopicki, Hal; Homma, Shunichi; Schmidt, Ann Marie; Oates, Peter J; Szabolcs, Matthias; Ramasamy, Ravichandran
2004 Aug;18(11):1192-1199, FASEB journal
— id: 130792, year: 2004, vol: 18, page: 1192, stat: Journal Article,

Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response
Liliensiek, Birgit; Weigand, Markus A; Bierhaus, Angelika; Nicklas, Werner; Kasper, Michael; Hofer, Stefan; Plachky, Jens; Grone, Herman-Josef; Kurschus, Florian C; Schmidt, Ann Marie; Yan, Shi Du; Martin, Eike; Schleicher, Erwin; Stern, David M; Hammerling G, G unterJ; Nawroth, Peter P; Arnold, Bernd
2004 Jun;113(11):1641-1650, Journal of clinical investigation
— id: 140642, year: 2004, vol: 113, page: 1641, stat: Journal Article,

RAGE axis: Animal models and novel insights into the vascular complications of diabetes
Naka, Yoshifumi; Bucciarelli, Loredana G; Wendt, Thoralf; Lee, Larisse K; Rong, Ling Ling; Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2004 Aug;24(8):1342-1349, Arteriosclerosis, thrombosis, & vascular biology
— id: 130795, year: 2004, vol: 24, page: 1342, stat: Journal Article,

RAGE modulates peripheral nerve regeneration via recruitment of both inflammatory and axonal outgrowth pathways
Rong, Ling Ling; Yan, Shi-Fang; Wendt, Thoralf; Hans, Diana; Pachydaki, Sophia; Bucciarelli, Loredana G; Adebayo, Adebukola; Qu, Wu; Lu, Yan; Kostov, Konstantin; Lalla, Evanthia; Yan, Shi Du; Gooch, Clifton; Szabolcs, Matthias; Trojaborg, Werner; Hays, Arthur P; Schmidt, Ann Marie
2004 Dec;18(15):1818-1825, FASEB journal
— id: 140605, year: 2004, vol: 18, page: 1818, stat: Journal Article,

Receptor-dependent vascular stress in diabetes
Schmidt AM; Hudson BI; Yan SF; Stern DM
Diabetes and cardiovascular disease : integrating science and clinical medicine Philadelphia : Lippincott Williams and Wilkins, 2004,
— id: 5834, year: 2004, vol: , page: ?, stat: Chapter,

RAGE and its ligands: a lasting memory in diabetic complications?
Yan, Shi-Fang; Ramasamy, Ravichandran; Bucciarelli, Loredana G; Wendt, Thoralf; Lee, Larisse K; Hudson, Barry I; Stern, David M; Lalla, Evanthia; DU Yan, Shi; Rong, Ling Ling; Naka, Yoshifumi; Schmidt, Ann Marie
2004 May;1(1):10-20, Diabetes & vascular disease research
— id: 130796, year: 2004, vol: 1, page: 10, stat: Journal Article,

RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain
Deane, Rashid; Du Yan, Shi; Submamaryan, Ram Kumar; LaRue, Barbara; Jovanovic, Suzana; Hogg, Elizabeth; Welch, Deborah; Manness, Lawrence; Lin, Chang; Yu, Jin; Zhu, Hong; Ghiso, Jorge; Frangione, Blas; Stern, Alan; Schmidt, Ann Marie; Armstrong, Don L; Arnold, Bernd; Liliensiek, Birgit; Nawroth, Peter; Hofman, Florence; Kindy, Mark; Stern, David; Zlokovic, Berislav
2003 Jul;9(7):907-913, Nature medicine
— id: 42003, year: 2003, vol: 9, page: 907, stat: Journal Article,

Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders
Hudson, Barry I; Bucciarelli, Loredana G; Wendt, Thoralf; Sakaguchi, Taichi; Lalla, Evanthia; Qu, Wu; Lu, Yan; Lee, Larisse; Stern, David M; Naka, Yoshifumi; Ramasamy, Ravichandran; Yan, Shi Du; Yan, Shi Fang; D'Agati, Vivette; Schmidt, Ann Marie
2003 Nov 1;419(1):80-88, Archives of biochemistry & biophysics. ABB
— id: 130797, year: 2003, vol: 419, page: 80, stat: Journal Article,

Central role of RAGE-dependent neointimal expansion in arterial restenosis
Sakaguchi, Taichi; Yan, Shi Fang; Yan, Shi Du; Belov, Dmitri; Rong, Ling Ling; Sousa, Monica; Andrassy, Martin; Marso, Steven P; Duda, Stephan; Arnold, Bernd; Liliensiek, Birgit; Nawroth, Peter P; Stern, David M; Schmidt, Ann Marie; Naka, Yoshifumi
2003 Apr;111(7):959-972, Journal of clinical investigation
— id: 140608, year: 2003, vol: 111, page: 959, stat: Journal Article,

Glucose, glycation, and RAGE: implications for amplification of cellular dysfunction in diabetic nephropathy
Wendt, Thoralf; Tanji, Nozomu; Guo, Jiancheng; Hudson, Barry I; Bierhaus, Angelika; Ramasamy, Ravichandran; Arnold, Bernd; Nawroth, Peter P; Yan, Shi Fang; D'Agati, Vivette; Schmidt, Ann Marie
2003 May;14(5):1383-1395, Journal of the American Society of Nephrology
— id: 130798, year: 2003, vol: 14, page: 1383, stat: Journal Article,

Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond
Yan, Shi Fang; Ramasamy, Ravichandran; Naka, Yoshifumi; Schmidt, Ann Marie
2003 Dec 12;93(12):1159-1169, Circulation research
— id: 130834, year: 2003, vol: 93, page: 1159, stat: Journal Article,

Suppression of experimental autoimmune encephalomyelitis by selective blockade of encephalitogenic T-cell infiltration of the central nervous system
Yan, Shirley ShiDu; Wu, Zhi-Ying; Zhang, Hui Ping; Furtado, Glaucia; Chen, Xi; Yan, Shi Fang; Schmidt, Ann Marie; Brown, Chris; Stern, Alan; LaFaille, Juan; Chess, Leonard; Stern, David M; Jiang, Hong
2003 Mar;9(3):287-293, Nature medicine
— id: 44897, year: 2003, vol: 9, page: 287, stat: Journal Article,

A modified hepatitis B virus core particle containing multiple epitopes of the Plasmodium falciparum circumsporozoite protein provides a highly immunogenic malaria vaccine in preclinical analyses in rodent and primate hosts
Birkett, A; Lyons, K; Schmidt, A; Boyd, D; Oliveira, G A; Siddique, A; Nussenzweig, R; Calvo-Calle, J M; Nardin, E
2002 Dec;70(12):6860-6870, Infection & immunity
— id: 165571, year: 2002, vol: 70, page: 6860, stat: Journal Article,

RAGE is a multiligand receptor of the immunoglobulin superfamily: implications for homeostasis and chronic disease
Bucciarelli, L G; Wendt, T; Rong, L; Lalla, E; Hofmann, M A; Goova, M T; Taguchi, A; Yan, S F; Yan, S D; Stern, D M; Schmidt, A M
2002 Jul;59(7):1117-1128, Cellular & molecular life sciences: CMLS
— id: 140640, year: 2002, vol: 59, page: 1117, stat: Journal Article,

RAGE and arthritis: the G82S polymorphism amplifies the inflammatory response
Hofmann, M A; Drury, S; Hudson, B I; Gleason, M R; Qu, W; Lu, Y; Lalla, E; Chitnis, S; Monteiro, J; Stickland, M H; Bucciarelli, L G; Moser, B; Moxley, G; Itescu, S; Grant, P J; Gregersen, P K; Stern, D M; Schmidt, A M
2002 May;3(3):123-135, Genes & immunity
— id: 93153, year: 2002, vol: 3, page: 123, stat: Journal Article,

Glycation and diabetes : the RAGE connection
Hudson BI; Hofmann MA; Bucciarelli L; Wendt T; Moser B; Lu Y; Qu W; Stern DM; D'Agati VD; Yan SD; Yan SF; Grant PJ; Schmidt Am
2002 ;83:1515-1521, Current science
— id: 140673, year: 2002, vol: 83, page: 1515, stat: Journal Article,

Receptor for advanced glycation endproducts (RAGE) and the complications of diabetes
Stern, David M; Yan, Shi Du; Yan, Shi Fang; Schmidt, Ann Marie
2002 Feb;1(1):1-15, Ageing research reviews
— id: 140613, year: 2002, vol: 1, page: 1, stat: Journal Article,

Receptor for advanced glycation endproducts: a multiligand receptor magnifying cell stress in diverse pathologic settings
Stern, David; Yan, Shi Du; Yan, Shi Fang; Schmidt, Ann Marie
2002 Dec 7;54(12):1615-1625, Advanced drug delivery reviews
— id: 140609, year: 2002, vol: 54, page: 1615, stat: Journal Article,

Receptor for advanced glycation endproducts (RAGE) and vascular inflammation: insights into the pathogenesis of macrovascular complications in diabetes
Wendt, Thoralf; Bucciarelli, Loredana; Qu, Wu; Lu, Yan; Yan, Shi Fang; Stern, David M; Schmidt, Ann Marie
2002 May;4(3):228-237, Current atherosclerosis reports
— id: 140612, year: 2002, vol: 4, page: 228, stat: Journal Article,

Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice
Goova, M T; Li, J; Kislinger, T; Qu, W; Lu, Y; Bucciarelli, L G; Nowygrod, S; Wolf, B M; Caliste, X; Yan, S F; Stern, D M; Schmidt, A M
2001 Aug;159(2):513-525, American journal of pathology
— id: 140634, year: 2001, vol: 159, page: 513, stat: Journal Article,

Involvement of microglial receptor for advanced glycation endproducts (RAGE) in Alzheimer's disease: identification of a cellular activation mechanism
Lue, L F; Walker, D G; Brachova, L; Beach, T G; Rogers, J; Schmidt, A M; Stern, D M; Yan, S D
2001 Sep;171(1):29-45, Experimental neurology
— id: 140635, year: 2001, vol: 171, page: 29, stat: Journal Article,

The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses
Schmidt, A M; Yan, S D; Yan, S F; Stern, D M
2001 Oct;108(7):949-955, Journal of clinical investigation
— id: 140637, year: 2001, vol: 108, page: 949, stat: Journal Article,

Key signaling pathways regulate the biological activities and accumulation of amyloid-beta
Wyss-Coray, T; McConlogue, L; Kindy, M; Schmidt, A M; Du Yan, S; Stern, D M
2001 Nov-Dec;22(6):967-973, Neurobiology of aging
— id: 140639, year: 2001, vol: 22, page: 967, stat: Journal Article,

Alzheimer's disease: inside, outside, upside down
Yan, S D; Schmidt, A M; Stern, D
2001 ;(67):15-22, Biochemical Society symposia
— id: 140633, year: 2001, vol: , page: 15, stat: Journal Article,

beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1
Giri, R; Shen, Y; Stins, M; Du Yan, S; Schmidt, A M; Stern, D; Kim, K S; Zlokovic, B; Kalra, V K
2000 Dec;279(6):C1772-C1781, American journal of physiology. Cell physiology
— id: 140627, year: 2000, vol: 279, page: C1772, stat: Journal Article,

RAGE: a multiligand receptor contributing to the cellular response in diabetic vasculopathy and inflammation
Schmidt, A M; Hofmann, M; Taguchi, A; Yan, S D; Stern, D M
2000 ;26(5):485-493, Seminars in thrombosis & hemostasis
— id: 140631, year: 2000, vol: 26, page: 485, stat: Journal Article,

The biology of the receptor for advanced glycation end products and its ligands
Schmidt, A M; Yan, S D; Yan, S F; Stern, D M
2000 Dec 20;1498(2-3):99-111, Biochimica & biophysica acta
— id: 140629, year: 2000, vol: 1498, page: 99, stat: Journal Article,

Cellular cofactors potentiating induction of stress and cytotoxicity by amyloid beta-peptide
Yan, S D; Roher, A; Chaney, M; Zlokovic, B; Schmidt, A M; Stern, D
2000 Jul 26;1502(1):145-157, Biochimica & biophysica acta
— id: 140625, year: 2000, vol: 1502, page: 145, stat: Journal Article,

Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis
Yan, S D; Zhu, H; Zhu, A; Golabek, A; Du, H; Roher, A; Yu, J; Soto, C; Schmidt, A M; Stern, D; Kindy, M
2000 Jun;6(6):643-651, Nature medicine
— id: 140623, year: 2000, vol: 6, page: 643, stat: Journal Article,

Soluble cellular adhesion molecules in proliferative vitreoretinopathy and proliferative diabetic retinopathy
Barile GR; Chang SS; Park LS; Reppucci VS; Schiff WM; Schmidt AM
1999 Sep;19(3):219-227, Current eye research
— id: 59362, year: 1999, vol: 19, page: 219, stat: Journal Article,

N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression
Kislinger, T; Fu, C; Huber, B; Qu, W; Taguchi, A; Du Yan, S; Hofmann, M; Yan, S F; Pischetsrieder, M; Stern, D; Schmidt, A M
1999 Oct 29;274(44):31740-31749, Journal of biological chemistry
— id: 140619, year: 1999, vol: 274, page: 31740, stat: Journal Article,

Activation of receptor for advanced glycation end products: a mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis
Schmidt, A M; Yan, S D; Wautier, J L; Stern, D
1999 Mar 19;84(5):489-497, Circulation research
— id: 140615, year: 1999, vol: 84, page: 489, stat: Journal Article,

Cellular cofactors for amyloid beta-peptide-induced cell stress. Moving from cell culture to in vivo
Yan, S D; Roher, A; Schmidt, A M; Stern, D M
1999 Nov;155(5):1403-1411, American journal of pathology
— id: 140620, year: 1999, vol: 155, page: 1403, stat: Journal Article,

Human blood-brain barrier receptors for Alzheimer's amyloid-beta 1- 40. Asymmetrical binding, endocytosis, and transcytosis at the apical side of brain microvascular endothelial cell monolayer
Mackic JB; Stins M; McComb JG; Calero M; Ghiso J; Kim KS; Yan SD; Stern D; Schmidt AM; Frangione B; Zlokovic BV
1998 Aug 15;102(4):734-743, Journal of clinical investigation
— id: 7669, year: 1998, vol: 102, page: 734, stat: Journal Article,

Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts
Park L; Raman KG; Lee KJ; Lu Y; Ferran LJ Jr; Chow WS; Stern D; Schmidt AM
1998 Sep;4(9):1025-1031, Nature medicine
— id: 59364, year: 1998, vol: 4, page: 1025, stat: Journal Article,

Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease
Du Yan, S; Zhu, H; Fu, J; Yan, S F; Roher, A; Tourtellotte, W W; Rajavashisth, T; Chen, X; Godman, G C; Stern, D; Schmidt, A M
1997 May 13;94(10):5296-5301, Proceedings of the National Academy of Sciences of the United States of America
— id: 140665, year: 1997, vol: 94, page: 5296, stat: Journal Article,

A murine model of accelerated diabetic atherosclerosis: supression by soluble receptor for advanced glycation endproducts
Park L; Raman KG; Lee KJ; Lu Y; Ginsberg MD; Ferran L Jr; Stern DM; Schmidt AM
1997 Oct 21;96(8 Suppl):550-550 abstract #3079, Circulation
— id: 59371, year: 1997, vol: 96, page: 550, stat: Journal Article,

What's the RAGE? The receptor for advanced glycation end products (RAGE) and the dark side of glucose
Yan, S D; Stern, D; Schmidt, A M
1997 Mar;27(3):179-181, European journal of clinical investigation
— id: 140663, year: 1997, vol: 27, page: 179, stat: Journal Article,

The receptor for advanced glycation end-products has a central role in mediating the effects of advanced glycation end-products on the development of vascular disease in diabetes mellitus
Hori, O; Yan, S D; Ogawa, S; Kuwabara, K; Matsumoto, M; Stern, D; Schmidt, A M
1996 ;11 Suppl 5:13-16, Nephrology, dialysis, transplantation
— id: 140662, year: 1996, vol: 11 Suppl 5, page: 13, stat: Journal Article,

An accelerated atherosclerosis model in diabetic apolipoprotein E knockout mice: vascular accumulation of advanced glycation
Park L; Hori O; Yan SD; Zou YS; Verstuyft J; Rubin EM; Liu JK; Yeo HC; Ames BN; Andaz S; Stern D; Schmidt AM
1996 Oct 15;94(8 Suppl):36-36 abstract #0200, Circulation
— id: 59372, year: 1996, vol: 94, page: 36, stat: Journal Article,

RAGE: a novel cellular receptor for advanced glycation end products
Schmidt, A M; Hori, O; Cao, R; Yan, S D; Brett, J; Wautier, J L; Ogawa, S; Kuwabara, K; Matsumoto, M; Stern, D
1996 Jul;45 Suppl 3:S77-S80, Diabetes
— id: 140658, year: 1996, vol: 45 Suppl 3, page: S77, stat: Journal Article,

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease
Yan, S D; Chen, X; Fu, J; Chen, M; Zhu, H; Roher, A; Slattery, T; Zhao, L; Nagashima, M; Morser, J; Migheli, A; Nawroth, P; Stern, D; Schmidt, A M
1996 Aug 22;382(6593):685-691, Nature
— id: 140659, year: 1996, vol: 382, page: 685, stat: Journal Article,

Advanced glycation endproducts interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice. A potential mechanism for the accelerated vasculopathy of diabetes
Schmidt, A M; Hori, O; Chen, J X; Li, J F; Crandall, J; Zhang, J; Cao, R; Yan, S D; Brett, J; Stern, D
1995 Sep;96(3):1395-1403, Journal of clinical investigation
— id: 140649, year: 1995, vol: 96, page: 1395, stat: Journal Article,

The dark side of glucose
Schmidt, A M; Yan, S D; Stern, D M
1995 Oct;1(10):1002-1004, Nature medicine
— id: 140648, year: 1995, vol: 1, page: 1002, stat: Journal Article,

Cellular receptors for advanced glycation end products. Implications for induction of oxidant stress and cellular dysfunction in the pathogenesis of vascular lesions
Schmidt, A M; Hori, O; Brett, J; Yan, S D; Wautier, J L; Stern, D
1994 Oct;14(10):1521-1528, Arteriosclerosis & thrombosis
— id: 140651, year: 1994, vol: 14, page: 1521, stat: Journal Article,

The endothelial cell binding site for advanced glycation end products consists of a complex: an integral membrane protein and a lactoferrin-like polypeptide
Schmidt, A M; Mora, R; Cao, R; Yan, S D; Brett, J; Ramakrishnan, R; Tsang, T C; Simionescu, M; Stern, D
1994 Apr 1;269(13):9882-9888, Journal of biological chemistry
— id: 140652, year: 1994, vol: 269, page: 9882, stat: Journal Article,

Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins
Yan, S D; Schmidt, A M; Anderson, G M; Zhang, J; Brett, J; Zou, Y S; Pinsky, D; Stern, D
1994 Apr 1;269(13):9889-9897, Journal of biological chemistry
— id: 140653, year: 1994, vol: 269, page: 9889, stat: Journal Article,

Survey of the distribution of a newly characterized receptor for advanced glycation end products in tissues
Brett, J; Schmidt, A M; Yan, S D; Zou, Y S; Weidman, E; Pinsky, D; Nowygrod, R; Neeper, M; Przysiecki, C; Shaw, A
1993 Dec;143(6):1699-1712, American journal of pathology
— id: 140655, year: 1993, vol: 143, page: 1699, stat: Journal Article,

Regulation of human mononuclear phagocyte migration by cell surface-binding proteins for advanced glycation end products
Schmidt, A M; Yan, S D; Brett, J; Mora, R; Nowygrod, R; Stern, D
1993 May;91(5):2155-2168, Journal of clinical investigation
— id: 140656, year: 1993, vol: 91, page: 2155, stat: Journal Article,

Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins
Neeper, M; Schmidt, A M; Brett, J; Yan, S D; Wang, F; Pan, Y C; Elliston, K; Stern, D; Shaw, A
1992 Jul 25;267(21):14998-15004, Journal of biological chemistry
— id: 140641, year: 1992, vol: 267, page: 14998, stat: Journal Article,

Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing
Honegger, A M; Dull, T J; Felder, S; Van Obberghen, E; Bellot, F; Szapary, D; Schmidt, A; Ullrich, A; Schlessinger, J
1987 Oct;51(2):199-209, Cell
— id: 170455, year: 1987, vol: 51, page: 199, stat: Journal Article,

Cisplatin and vinblastine chemotherapy for metastatic non-small cell carcinoma followed by irradiation in patients with regional disease
Blum RH; Cooper J; Schmidt AM; Ashinoff R; Collins A; Wernz JC; Speyer JL; Boyd A; Muggia FM
1986 Mar;70(3):333-337, Cancer treatment reports
— id: 15695, year: 1986, vol: 70, page: 333, stat: Journal Article,

Phase II trial of cyclophosphamide and cis-platinum for non-small cell bronchogenic carcinoma
Schmidt AM; Blum RH; Clayton M; Speyer JL; Bottino J; Muggia FM
1984 Dec;7(6):725-727, American journal of clinical oncology
— id: 35105, year: 1984, vol: 7, page: 725, stat: Journal Article,