Barry P Rosenzweig, M.D.

Inside and out: an epicardial lead gone astray
Hong, Susie N; Rosenzweig, Barry; Crooke, Gregory A; Kronzon, Itzhak; Srichai, Monvadi B
2011 ;38(2):204-205, Texas Heart Institute journal
— id: 133461, year: 2011, vol: 38, page: 204, stat: Journal Article,

Moderate doses of hGH (0.64 mg/d) improve lipids but not cardiovascular function in GH-deficient adults with normal baseline cardiac function
Newman, Connie B; Frisch, Katalin A; Rosenzweig, Barry; Roubenoff, Ronenn; Rey, Mariano; Kidder, Teresa; Kong, Yuan; Pursnani, Amit; Sedlis, Steven P; Schwartzbard, Arthur; Kleinberg, David L
2011 Jan;96(1):122-132, Journal of clinical endocrinology & metabolism
CONTEXT: Data regarding effects of lower-dose GH on cardiopulmonary function in GH-deficient (GHD) adults are limited. OBJECTIVES: The objective was to assess effects of lower-dose GH on exercise capacity and echocardiographic parameters in GHD adults. DESIGN: The study was a 6-month double-blind, placebo-controlled randomized trial. SETTING: The study was conducted at the General Clinical Research Center. PARTICIPANTS: Thirty hypopituitary adults with GHD were studied. INTERVENTION: Subjects were randomized to recombinant human GH or placebo for 6 months, followed by open-label recombinant human GH for 12 months. MAIN OUTCOME MEASURES: Primary endpoints were exercise duration, maximal oxygen consumption, and left ventricular ejection fraction. Secondary endpoints were echocardiographic indices of systolic and diastolic function, left ventricular mass, lipids, and body composition. RESULTS: In the 6-month double-blind phase, mean GH dose was 0.64 mg/d. Mean IGF-I sd score increased from -4.5 to -1.0. Exercise duration, maximal oxygen consumption, left ventricular ejection fraction, and other echocardiographic parameters were normal at baseline and did not change. GH decreased total and low-density lipoprotein cholesterol by 7.5% (P = 0.016) and 14.7% (P = 0.002) (P = 0.04 vs. placebo). Mean lean body mass increased by 2.2 kg (P = 0.004), fat mass decreased by 1.7 kg (P = 0.21), and percent body fat decreased by 2.5% (P = 0.018), although between-group changes were not significant. CONCLUSIONS: Human GH did not improve exercise performance or echocardiographic parameters or decrease fat mass but significantly decreased total and low-density lipoprotein cholesterol, increased IGF-I, and increased lean body mass. These results indicate that responses to human GH are variable and should be assessed at baseline and during treatment
— id: 138237, year: 2011, vol: 96, page: 122, stat: Journal Article,

Normal intima-media thickness on carotid ultrasound reliably excludes an ischemic cause of cardiomyopathy
Reynolds, Harmony R; Steckman, David A; Tunick, Paul A; Kronzon, Itzhak; Lobach, Iryna; Rosenzweig, Barry P
2010 Jun;159(6):1059-1066, American heart journal
BACKGROUND: Coronary artery disease (CAD) is the most common cause of left ventricular systolic dysfunction (LVSD). Patients with ischemia as the cause of LVSD may warrant revascularization. Angiography is the most accurate method of CAD diagnosis but is invasive, expensive, and associated with some risk. Noninvasive imaging for CAD often involves expensive equipment, radiation exposure, medication, and/or contrast administration. Carotid ultrasound with measurement of intima-media thickness (IMT) is safe and inexpensive. Carotid IMT is well correlated with the presence of CAD. We assessed the accuracy of carotid ultrasound for identification of CAD as a potential etiology of LVSD. METHODS: Patients with LVSD (ejection fraction < or =40%) of uncertain etiology referred for angiography underwent carotid ultrasound. Patients with history of myocardial infarction were excluded. Two experienced cardiologists blinded to CAD status determined common carotid artery (CCA) IMT and plaque. Significant CAD was defined as > or =50% stenosis of any major artery. Ischemic LVSD was defined as (1) left main and/or proximal left anterior descending coronary artery > or =75% or (2) > or =2 major arteries with > or =75% stenosis. RESULTS: Mean ejection fraction was 27% +/- 10% in 150 patients. Significant CAD was found in 64 (42.7%) and ischemic LVSD in 40 (26.7%). Carotid plaque was seen in 95 (63.3%). Mean CCA IMT was > or =0.9 mm in 69 (46.0%). The combination of mean CCA IMT <0.9 mm and no plaque had negative predictive value for ischemic LVSD of 98%. CONCLUSIONS: Carotid ultrasound with IMT measurement is a valuable screening tool for excluding an ischemic etiology of LVSD when CAD is suspected
— id: 110089, year: 2010, vol: 159, page: 1059, stat: Journal Article,

Phase II study of darinaparsin in patients with advanced hepatocellular carcinoma
Wu, Jennifer; Henderson, Charles; Feun, Lynn; Van Veldhuizen, Peter; Gold, Philip; Zheng, Hui; Ryan, Theresa; Blaszkowsky, Lawrence S; Chen, Haobin; Costa, Max; Rosenzweig, Barry; Nierodzik, MaryLynn; Hochster, Howard; Muggia, Franco; Abbadessa, Giovanni; Lewis, Jonathan; Zhu, Andrew X
2010 Oct;28(5):670-676, Investigational new drugs
BACKGROUND: Darinaparsin is a novel organic arsenic that reaches higher intracellular concentration with decreased toxicity compared to inorganic arsenic. We conducted a multi-center phase II study with darinaparsin in patients with advanced HCC. METHODS: Eligibility criteria included unresectable or metastatic measurable HCC, up to two prior systemic treatments, ECOG performance status < or = 2, Child Pugh Class A or B and adequate organ functions. Darinaparsin was administered at 420 mg/m(2) intravenously, twice weekly at least 72 h apart for 3 weeks in a 4-week cycle. The primary end point was response rate. A Simon two-stage design was used. RESULTS: Among 15 patients in the first stage, no objective responses were observed. Two patients had stable disease. The median number of cycles on study per patient was 2 (1-6). The median progression free survival and overall survival were 55 days (95% confidence interval: 50-59) and 190 days (95% confidence interval: 93-227), respectively. No treatment related hospitalizations or deaths occurred. Treatment related grade 1-2 toxicities included nausea, vomiting (26.7% each), fatigue (20%), anorexia and diarrhea (13.3% each). Grade 3 anorexia, wheezing, agitation, abdominal pain and SGPT were observed in 1 patient each (6.7%). One patient experienced grade 4 hypoglycemia (6.7%). CONCLUSIONS: Darinaparsin could be safely administered with tolerable toxicity profiles, and no QTc prolongation in patients with advanced HCC. However, at this dose and schedule, it has shown no objective responses in HCC and this trial was terminated as planned after the first stage of efficacy analysis
— id: 138148, year: 2010, vol: 28, page: 670, stat: Journal Article,

Total anomalous pulmonary venous connection in an adult: comprehensive multimodality evaluation
Vavas, Eleni; Rosenzweig, Barry P; Meyer, David B; Srichai, Monvadi B
2009 Sep;4(5):384-386, Congenital heart disease
An unusual case of total anomalous pulmonary venous connection surviving to adulthood without surgical correction is presented. Transthoracic echocardiography first led to this diagnosis and magnetic resonance imaging refined the anatomic diagnosis leading to successful surgical correction
— id: 102163, year: 2009, vol: 4, page: 384, stat: Journal Article,

Correlation between plasma osteopontin levels and aortic valve calcification: potential insights into the pathogenesis of aortic valve calcification and stenosis
Yu, Pey-Jen; Skolnick, Adam; Ferrari, Giovanni; Heretis, Katherine; Mignatti, Paolo; Pintucci, Giuseppe; Rosenzweig, Barry; Diaz-Cartelle, Juan; Kronzon, Itzhak; Perk, Gila; Pass, Harvey I; Galloway, Aubrey C; Grossi, Eugene A; Grau, Juan B
2009 Jul;138(1):196-199, Journal of thoracic & cardiovascular surgery
OBJECTIVE: The inflammatory process of aortic stenosis involves the differentiation of aortic valve myofibroblasts into osteoblasts. Osteopontin, a proinflammatory glycoprotein, both stimulates differentiation of myofibroblasts and regulates the deposition of calcium by osteoblasts. Osteopontin levels are increased in patients with such conditions as end-stage renal disease, ectopic calcification, and autoimmune disease. We hypothesized that increased plasma osteopontin levels might be associated with the presence of aortic valve calcification and stenosis. METHODS: Venous blood from volunteers older than 65 years undergoing routine echocardiographic analysis or aortic valve surgery for aortic stenosis was collected. Plasma osteopontin levels were measured by means of enzyme-linked immunosorbent assay. The presence of aortic stenosis was defined as an aortic valve area of less than 2.0 cm(2). Aortic valve calcification was assessed by using a validated echocardiographic grading system (1, none; 2, mild; 3, moderate; 4, severe). Comparisons were performed with nonpaired t tests. RESULTS: Aortic stenosis was present in 23 patients (mean age, 78 years) and was absent in 7 patients (mean age, 72 years). Aortic valve calcification scores were 3.5 +/- 0.6 and 1.3 +/- 0.5 in patients with and without aortic stenosis, respectively (P < .001). Patients with no or mild aortic valve calcification had lower osteopontin levels compared with patients with moderate or severe aortic valve calcification (406.1 +/- 165.8 vs 629.5 +/- 227.5 ng/mL, P = .01). Similarly, patients with aortic stenosis had higher osteopontin levels compared with patients without aortic stenosis (652.2 +/- 218.7 vs 379.7 +/- 159.9 ng/mL, P < .01). CONCLUSION: Increased levels of plasma osteopontin are associated with the presence of aortic valve calcification and stenosis. These findings suggest that osteopontin might play a functional role in the pathogenesis of calcific aortic stenosis
— id: 100629, year: 2009, vol: 138, page: 196, stat: Journal Article,

Carotid intima-media thickness measurement is an excellent screening tool for the detection of severe coronary artery disease associated with left ventricular systolic dysfunction
Reynolds, HB; Steckman, DA; Hynes, PJ; Sarswat, N; Tunick, PA; Vargas, BD; Khandwalla, RM; Kronzon, I; Rosenzweig, BP
2008 MAR 11 ;51(10):A225-A225, Journal of the American College of Cardiology
— id: 78386, year: 2008, vol: 51, page: A225, stat: Journal Article,

Rare flow pattern in a patient with cor triatriatum
Ghalchi, Michael; Rosenzweig, Barry P; Colvin, Stephen B; Tunick, Paul A; Kronzon, Itzhak
2005 Sep;22(8):705-706, Echocardiography
Doppler echocardiography demonstrated a rare flow pattern due to cor triatriatum that is also present in subvalvular or supravalvular mitral stenosis: a forward gradient, in both systole and diastole
— id: 61260, year: 2005, vol: 22, page: 705, stat: Journal Article,

Localized pericardial hematoma presenting with acute hypoxemia
Saunders, Paul C; Grau, Juan B; Chen, Carol L; Zervos, Michael; Schwartz, Charles F; Colvin, Stephen B; Rosenzweig, Barry P; Ribakove, Greg H
2005 Jun;79(6):2141-2143, Annals of thoracic surgery
Localized pericardial hematomas after cardiac surgery may have atypical clinical presentations due to regional alterations in cardiac function and hemodynamics. We report a case of extravascular thrombus that compressed the main pulmonary artery and produced acute hypoxemia due to right-to-left shunting across a patent foramen ovale. We review the pathophysiology leading to this finding and the echocardiographic studies that established the diagnosis
— id: 56009, year: 2005, vol: 79, page: 2141, stat: Journal Article,

Saphenous vein graft aneurysm masquerading as a right atrial mass
Yatskar, Leonid; Rosenzweig, Barry P; Attubato, Michael; Axel, Leon; Tunick, Paul A; Kronzon, Itzhak
2005 Mar;22(3):263-265, Echocardiography
We report a case of a large saphenous vein graft (SVG) aneurysm masquerading as a right atrial mass on transesophageal echocardiogram. Cardiac magnetic resonance angiography reliably made a diagnosis of SVG aneurysm extrinsically compressing right atrium. This case illustrates the importance of using combined imaging modalities for the diagnosis and management of cardiac masses
— id: 55961, year: 2005, vol: 22, page: 263, stat: Journal Article,

Periaortitis: gadolinium-enhanced magnetic resonance imaging and response to therapy in four patients
Mitnick, Hal; Jacobowitz, Glenn; Krinsky, Glen; Eberle, Mark; Rosenzweig, Barry; Willis, David; Rockman, Caron; Riles, Thomas
2004 Feb;18(1):100-107, Annals of vascular surgery
The objective of this study was to define clinical and imaging characteristics of periaortitis prior to and after therapy with immunosuppressive drugs. Four consecutive patients with periaortitis (two secondary to atherosclerosis and two with rheumatic diseases) were studied with contrast-enhanced CT and magnetic resonance angiography (MRA), rheumatologic serologies, and acute-phase reactants. All were treated with corticosteroids and two patients received immunosuppressive agents. Patients were followed with serial MRA scans, CT scans, and clinical exams. Prior to treatment, all patients demonstrated a rind of periaortic tissue, which was enhanced with both contrast-enhanced CT as well as gadolinium-enhanced MRA. Clinical symptoms resolved and rind contracture occurred in all cases following therapy. Enhancement of the rind persisted despite the clinical improvement in all patients. No patient developed an aortic aneurysm or retroperitoneal fibrosis during the follow-up period. Corticosteroid/immunosuppressive treatment was continued for an average of 41 months. At 62 months of total follow-up, there has been no recurrence of periaortitis by clinical and/or radiologic exam. Treatment of periaortitis with corticosteroids and immunosuppression therapy leads to resolution of clinical symptoms and radiologic contracture of the periaortic rind. Patients responded to therapy without developing progressive fibrosis or aneurysm. MRA allows safe and repetitive imaging of periaortitis and provides excellent definition of lumenal abnormalities including plaque rupture
— id: 46180, year: 2004, vol: 18, page: 100, stat: Journal Article,

Bilateral pulmonary artery compression and obstruction by tumor: diagnosis by unusual Doppler flow patterns
Katz, Edward S; Shah, Alan; Rosenzweig, Barry P; Tunick, Paul A; Kronzon, Itzhak
2003 Feb;16(2):185-187, Journal of the American Society of Echocardiography
Pulmonary artery obstruction may be caused by tumor within or external to the arteries. Presented here is a patient with life-threatening compromise in pulmonary flow that was caused by a pulmonary neoplasm. The Doppler echocardiogram showed subtotal narrowing of the right pulmonary artery and total occlusion of the left pulmonary artery. In addition, the beneficial effects of chemotherapy were documented by Doppler
— id: 36576, year: 2003, vol: 16, page: 185, stat: Journal Article,

Echocardiography in the identification of unusual surgical errors resulting from attempted closure of secundum atrial septal defects: Report of two cases
Kronzon, Itzhak; Tunick, Paul A; Rosenzweig, Barry P; Katz, Edward S; Colvin, Stephen B
2003 Jul;16(7):774-776, Journal of the American Society of Echocardiography
— id: 36723, year: 2003, vol: 16, page: 774, stat: Journal Article,

The a-dip of aortic regurgitation
Sethi, Jesse S; Shah, Alan; Benenstein, Ricardo; Rosenzweig, Barry P; Tunick, Paul A; Kronzon, Itzhak
2003 Oct;16(10):1078-1079, Journal of the American Society of Echocardiography
Echocardiography has become the diagnostic technique of choice for delineating the intracardiac hemodynamics in a host of pathophysiologic states. Pressures and flows can be estimated or measured with enough accuracy to allow for clinical decision-making. We present a case with an unusual Doppler echocardiographic finding and discuss its derivation
— id: 39027, year: 2003, vol: 16, page: 1078, stat: Journal Article,

The risk of the development of aortic stenosis in patients with "benign" aortic valve thickening
Cosmi, John E; Kort, Smadar; Tunick, Paul A; Rosenzweig, Barry P; Freedberg, Robin S; Katz, Edward S; Applebaum, Robert M; Kronzon, Itzhak
2002 Nov 11;162(20):2345-2347, Archives of internal medicine
BACKGROUND: Aortic valve thickening (AVT) without aortic stenosis (AS) is common and was often considered benign. However, it has recently been found to be associated with increased morbidity and mortality. It is unknown whether patients with AVT are at risk for the development of AS. METHODS: Our echocardiography database from 1987 to 1993 was searched for cases of AVT with at least 1 year of echocardiographic follow-up. The risk of the development of AS was compared in patients with and without AVT. RESULTS: There were 2131 patients with AVT and at least 1 year of echocardiographic follow-up. Aortic stenosis developed in 338 patients (15.9%) (mild, 10.5%; moderate, 2.9%; and severe, 2.5%). Multivariate analysis, including age, left ventricular hypertrophy, and mitral annular calcification, revealed that only mitral annular calcification was independently and significantly associated with progression to AS. CONCLUSIONS: Aortic valve thickening without stenosis is common, and it may progress to significant AS. It is possible that this development of AS may be responsible for some of the increased morbidity and mortality in patients with AVT
— id: 39568, year: 2002, vol: 162, page: 2345, stat: Journal Article,

Quantification of left-to-right shunt in patent ductus arteriosus with the PISA method
Kronzon, Itzhak; Tunick, Paul A; Rosenzweig, Barry P
2002 Apr;15(4):376-378, Journal of the American Society of Echocardiography
Direct Doppler echocardiographic calculation of shunt flow in patent ductus arteriosus (PDA) may be difficult because the orifice area is not well visualized. We used proximal isovelocity surface area (PISA) method to calculate the effective shunt orifice area and the shunt volume in a patient with PDA. The PISA calculation correlated well with shunt estimation by echocardiographic volumetric methods and by oximetry
— id: 32262, year: 2002, vol: 15, page: 376, stat: Journal Article,

Effect of treatment on the incidence of stroke and other emboli in 519 patients with severe thoracic aortic plaque
Tunick, Paul A; Nayar, Ambika C; Goodkin, Gregory M; Mirchandani, Sunil; Francescone, Steven; Rosenzweig, Barry P; Freedberg, Robin S; Katz, Edward S; Applebaum, Robert M; Kronzon, Itzhak
2002 Dec 15;90(12):1320-1325, American journal of cardiology
Severe aortic plaques seen on transesophageal echocardiography (TEE) are a high-risk cause of stroke and peripheral embolization. Evidence to guide therapy is lacking. Retrospective information was obtained regarding the occurrence of embolic events (stroke, transient ischemic attacks, or peripheral emboli) in 519 patients with severe thoracic aortic plaque seen on TEE since 1988. Treatment with statins, warfarin, or antiplatelet medications was noted. Treatment was not randomized. In a matched-paired analysis, each patient taking each class of therapy was matched for age, gender, previous embolic event, hypertension, diabetes, congestive failure, and atrial fibrillation to someone not taking that medication. Multivariate analysis was also performed. An embolic event occurred in 111 patients (21%). Multivariate analysis showed that statin use was independently protective against recurrent events (p = 0.0001). Matched analysis also showed a protective effect of statins (p = 0.0004; absolute risk reduction 17%, relative risk reduction 59%, number needed to treat [n = 6]). No protective effect was found for warfarin or antiplatelet drugs. The odds ratio for embolic events was 0.3 (95% confidence interval [CI] 0.2 to 0.6) for statin therapy, 0.7 (95% CI 0.4 to 1.2) for warfarin, and 1.4 (95% CI 0.8 to 2.4) for antiplatelet agents. Thus, there is a protective effect of statin therapy, and no significant benefit of warfarin or antiplatelet drugs on the incidence of stroke and other embolic events in patients with severe thoracic aortic plaque on TEE
— id: 36577, year: 2002, vol: 90, page: 1320, stat: Journal Article,

Unusual echocardiographic views of bicuspid and tricuspid pulmonic valves
McAleer E; Kort S; Rosenzweig BP; Katz ES; Tunick PA; Phoon CK; Kronzon I
2001 Oct;14(10):1036-1038, Journal of the American Society of Echocardiography
The pulmonary artery is typically seen on transthoracic echocardiography in its longitudinal axis. Therefore, short axis views of the pulmonic valve leaflets are not generally obtained, and the distinction between tricuspid and bicuspid pulmonic valves is difficult or impossible. Bicuspid pulmonic valve is one cause of pulmonic stenosis, which is especially common in tetralogy of Fallot. Presented here are 2 patients in whom the orientation of the pulmonary artery was unusual, and the pulmonic valve was seen en face. The first patient had tetralogy of Fallot and a bicuspid pulmonic valve. The severe obstruction to right ventricular outflow was infundibular. The second patient had severe stenosis of a tricuspid pulmonic valve, which was treated with balloon valvuloplasty. These unusual views of the pulmonic valve leaflets were obtained because of anterior displacement of the pulmonary artery, and precise anatomic delineation of the problem in each case was possible with transthoracic echocardiography
— id: 26604, year: 2001, vol: 14, page: 1036, stat: Journal Article,

Abdominal aortic aneurysms and thoracic aortic atheromas
Reynolds HR; Tunick PA; Kort S; Rosenzweig BP; Freedberg RS; Katz ES; Applebaum RM; Portnay EL; Adelman MA; Attubato MJ; Kronzon I
2001 Nov;14(11):1127-1131, Journal of the American Society of Echocardiography
BACKGROUND: Abdominal aortic aneurysm (AAA) is associated with atherosclerosis elsewhere. Thoracic aortic atheromas (ATHs) seen on transesophageal echocardiography (TEE) are an important cause of stroke and peripheral embolization. The purposes of this study were to determine whether an association exists between AAA and ATHs and to assess the importance of screening patients with ATHs for AAA. METHODS: For the retrospective analysis, 109 patients with AAA and 109 matched controls were compared for the prevalence of ATHs on TEE and for historical variables. For the prospective analysis, screening for AAA on ultrasonography was performed in 364 patients at the time of TEE. RESULTS: Results of the retrospective analysis showed that ATHs were present in 52% of patients with AAA and in 25% of controls (odds ratio [OR] = 3.3; P =.00003). There was a significantly higher prevalence of hypertension, myocardial infarction, heart failure, smoking, and carotid or peripheral arterial disease in patients with AAA. However, only ATHs were independently associated with AAA on multivariate analysis (P =.001). Results of the prospective analysis showed that screening at the time of TEE in 364 patients revealed AAA in 13.9% of those with ATHs and in 1.4% of those without ATHs (P <.0001; OR = 11.4). CONCLUSIONS: (1) There is a strong, highly significant association between abdominal aneurysm and thoracic atheromas. (2) Patients with AAA may be at high risk for stroke because of the concomitance of thoracic aortic atheromas. (3) The high prevalence of abdominal aneurysm in patients with thoracic atheromas suggests that screening for abdominal aneurysm should be carried out in all patients with thoracic atheromas identified by TEE
— id: 26574, year: 2001, vol: 14, page: 1127, stat: Journal Article,

Thromboembolus from a ligated left atrial appendage
Rosenzweig BP; Katz E; Kort S; Schloss M; Kronzon I
2001 May;14(5):396-398, Journal of the American Society of Echocardiography
The left atrial appendage of patients with mitral valve disease is commonly a source of thromboembolus and is often ligated during mitral valve surgery to diminish this risk. However, ligation is often incomplete. We describe a patient with a stroke whose only source of embolus was an incompletely ligated left atrial appendage. Attempts to exclude the left atrial appendage from the arterial circulation by suture ligation may not decrease the risk of thromboemboli and instead may increase such risk
— id: 20686, year: 2001, vol: 14, page: 396, stat: Journal Article,

Echo contrast-enhanced diagnosis of atrial septal defect
Rosenzweig BP; Nayar AC; Varkey MP; Kronzon I
2001 Feb;14(2):155-157, Journal of the American Society of Echocardiography
Pulsed wave, continuous wave, and color flow Doppler imaging as well as intravenously administered agitated saline solution can detect intracardiac shunts during transthoracic echocardiography. Ultrasonographic contrast agents have greatly improved the visualization of left heart chambers and can enhance signals from blood flow within chambers and across valves, increasing the sensitivity of Doppler techniques. We describe a patient in whom the use of echo contrast media during transthoracic echocardiography allowed the detection of a previously unseen atrial septal defect. Combining such modalities may help to increase the sensitivity of transthoracic echocardiography and may eliminate the need for transesophageal echocardiography in selected patients
— id: 26795, year: 2001, vol: 14, page: 155, stat: Journal Article,

Aortic valve replacement in patients with aortic stenosis and severe left ventricular dysfunction
Powell DE; Tunick PA; Rosenzweig BP; Freedberg RS; Katz ES; Applebaum RM; Perez JL; Kronzon I
2000 May 8;160(9):1337-1341, Archives of internal medicine
BACKGROUND: The outcome of aortic valve replacement for severe aortic stenosis is worse in patients with impaired left ventricular function. Such dysfunction in aortic stenosis may be reversible if caused by afterload mismatch, but not if it is caused by superimposed myocardial infarction. METHODS: From our echocardiography database, 55 patients with severe aortic stenosis (valve area < or =0.75 cm2) and ejection fractions of 30% or lower who subsequently underwent aortic valve replacement were included. The operative mortality and clinical follow-up were detailed. RESULTS: There were 10 perioperative deaths (operative mortality, 18%). Twenty (36%) of the 55 patients had a prior myocardial infarction. In the 35 patients without prior myocardial infarction, there was only 1 death (3%). In contrast, 9 of 20 patients with prior myocardial infarction died (mortality rate, 45%; P< or =.001). The factors significantly associated with perioperative death on univariate analysis (functional class, mean aortic gradient, and prior myocardial infarction) were entered into a model for stepwise logistic regression. This multivariate analysis showed that only prior myocardial infarction was independently associated with perioperative death (odds ratio, 14.9; 95% confidence interval, 2.4-92.1; P = .004). CONCLUSIONS: The risk of aortic valve replacement in patients with severe aortic stenosis and severely reduced left ventricular systolic function is extremely high if the patients have had a prior myocardial infarction. This information should be factored into the risk-benefit analysis that is done preoperatively for these patients, and it may preclude operation for some
— id: 11701, year: 2000, vol: 160, page: 1337, stat: Journal Article,

Contrast echocardiography clarifies uninterpretable wall motion in intensive care unit patients [see comments]
Reilly JP; Tunick PA; Timmermans RJ; Stein B; Rosenzweig BP; Kronzon I
2000 Feb;35(2):485-490, Journal of the American College of Cardiology
OBJECTIVES: The study examined the value of contrast echocardiography in the assessment of left ventricular (LV) wall motion in intensive care unit (ICU) patients. BACKGROUND: Echocardiograms done in the ICU are often suboptimal. The most common indication is the evaluation of LV wall motion and ejection fraction (EF). METHODS: Transthoracic echocardiograms were done in 70 unselected ICU patients. Wall motion was evaluated on standard echocardiography (SE), harmonic echocardiography (HE), and after intravenous (IV) contrast echocardiography (CE) using a score for each of 16 segments. A confidence score was also given for each segment with each technique (unable to judge; not sure; sure). The EF was estimated visually for each technique, and a confidence score was applied to the EF. RESULTS: Uninterpretable wall motion was present in 5.4 segments/patient on SE, 4.4 on HE (p = 0.2), and 1.1 on CE (p < 0.0001). An average of 7.8 segments were read with surety on SE, 9.2 on HE (p = 0.1), and 13.7 on CE (p < 0.0001). Ejection fraction was uninterpretable in 23% on SE, 13% on HE (p = 0.14), and 0% on CE (p = 0.002 vs. HE; p < 0.0001 vs. SE). The EF was read with surety in 56% of patients on SE, 62% on HE (p = 0.47), and 91% on CE (p < 0.0001). Thus, wall motion was seen with more confidence on CE. More importantly, the actual readings of segmental wall motion and EF significantly differed using CE. CONCLUSIONS: CE should be used in all ICU patients with suboptimal transthoracic echocardiograms
— id: 8556, year: 2000, vol: 35, page: 485, stat: Journal Article,

Unusual myocardial hypertrophy in a young woman [In Process Citation]
Rosenzweig BP; Strouse D; Kronzon I
2000 Jul;17(5):451-451, Echocardiography
— id: 11508, year: 2000, vol: 17, page: 451, stat: Journal Article,

Unusual eustachian valve function
Saric M; Rosenzweig BP; Kronzon I
2000 Apr;13(4):316-318, Journal of the American Society of Echocardiography
The eustachian valve directs oxygen-rich blood from the inferior vena cava toward the foramen ovale and away from the tricuspid valve during fetal development. Ordinarily, it does not prevent reflux of right atrial blood back into the inferior vena cava because it does not function as a true valve. Here we describe an unusual adult patient with severe tricuspid valve regurgitation in whom the eustachian valve did function as a true, albeit regurgitant, valve
— id: 11764, year: 2000, vol: 13, page: 316, stat: Journal Article,

The role of transesophageal echocardiography in the diagnosis and treatment of right atrial thrombi
Schwartzbard AZ; Tunick PA; Rosenzweig BP; Kronzon I
1999 Jan;12(1):64-69, Journal of the American Society of Echocardiography
Twenty patients with right atrial thrombi were identified through the use of transthoracic and transesophageal echocardiography. Transesophageal echocardiography identified right atrial thrombi in all 20 cases. Transthoracic echocardiography showed definite thrombi in only 6 (30%) cases and suggested thrombus in another 2 (10%) patients. Thus transthoracic echocardiography results were false-negative for right atrial thrombus in 60% of cases. All 3 thrombi found within the right atrial appendage and 2 of 3 thrombi on pacemaker wires were missed by transthoracic echocardiography. There was no significant difference in the mean size between those thrombi seen (1.37 +/- 0.6 cm) and those missed (1.5 +/- 0.9 cm) by transthoracic echocardiography. Transesophageal echocardiography also significantly affected treatment. Anticoagulation was initiated or amplified in 13 patients. In 8 of these 13, thrombi were seen only by transesophageal echocardiography. Surgery was performed to remove thrombi in 7 cases, and in 3 (43%) cases it was because of thrombi seen only by transesophageal echocardiography. This study suggests that transesophageal echocardiography should be performed whenever right atrial thrombi are suspected. Transesophageal echocardiography has a significant effect on the diagnosis and management of patients with right atrial thrombi
— id: 7443, year: 1999, vol: 12, page: 64, stat: Journal Article,

Transesophageal echocardiography in a case of cardiac compression: was it therapeutic?
Rosenzweig BP; Stern A; Kronzon I
1998 May;11(5):494-496, Journal of the American Society of Echocardiography
Cardiac compression is a potentially life-threatening complication of heart surgery. This syndrome often has atypical manifestations, challenging our ability to make a rapid diagnosis and to institute emergent, life-saving treatment. We recently evaluated one such patient who showed cardiac compression caused by an unusual paracardiac mass. The addition of transesophageal echocardiography to the usual transthoracic study may have played more than just a diagnostic role in this case
— id: 12113, year: 1998, vol: 11, page: 494, stat: Journal Article,

Correlation between plasma homocyst(e)ine and aortic atherosclerosis
Konecky N; Malinow MR; Tunick PA; Freedberg RS; Rosenzweig BP; Katz ES; Hess DL; Upson B; Leung B; Perez J; Kronzon I
1997 May;133(5):534-540, American heart journal
Plasma homocyst(e)ine [H(e)] levels correlate with the prevalence of arterial occlusive diseases. Recently, transesophageal echocardiography (TEE) has been used to evaluate patients with atherosclerotic plaques in the thoracic aorta. The purpose of this study was to determine whether H(e) levels correlate with the degree of atherosclerotic plaque in the thoracic aorta (ATH) as seen on TEE. Maximum plaque areas for three locations in the thoracic aorta (arch, proximal descending, and distal descending) were measured with TEE in 156 patients. Maximum plaque areas for these locations were added to yield an estimate of ATH. ATH and H(e) levels, and levels of folic acid, vitamin B12, and pyridoxal 5'-phosphate were measured in a double-blind manner. Univariate analysis demonstrated a significant correlation of H(e) with ATH (r = 0.3, p< 0.001). On multivariate analysis, H(e) was independently predictive of ATH (r for the model including H(e) was 0.63, p < 0.0001). Plasma H(e) levels are therefore significantly and independently correlated with the degree of atherosclerosis in the thoracic aorta
— id: 12323, year: 1997, vol: 133, page: 534, stat: Journal Article,

Visualization and identification of the left common carotid and left subclavian arteries: a transesophageal echocardiographic approach [see comments]
Katz ES; Konecky N; Tunick PA; Rosenzweig BP; Freedberg RS; Kronzon I
1996 Jan-Feb;9(1):58-61, Journal of the American Society of Echocardiography
— id: 7008, year: 1996, vol: 9, page: 58, stat: Journal Article,

Right atrial thrombus complicating mitral valvuloplasty
Konecky N; Rosenzweig BP; Katz ES; Kronzon I
1996 Oct;132(4):893-894, American heart journal
— id: 7077, year: 1996, vol: 132, page: 893, stat: Journal Article,

Intraaortic mass after repair of an aortic dissection
Rosenzweig BP; Colvin SB; Leitman BS; Kronzon I
1996 Jan-Feb;9(1):100-103, Journal of the American Society of Echocardiography
After graft repair of an ascending aortic aneurysm, a patient was seen by us with a chest x-ray film indicating a retained foreign body. Mediastinal exploration had been unrevealing. Transesophageal echocardiography demonstrated the nature and exact location of the foreign body and therefore was instrumental in directing its retrieval
— id: 12694, year: 1996, vol: 9, page: 100, stat: Journal Article,

Images in cardiovascular medicine. Impending paradoxical embolus
Rosenzweig BP; Glassman L; Kronzon I
1996 Jan 15;93(2):387-387, Circulation
— id: 12655, year: 1996, vol: 93, page: 387, stat: Journal Article,

Aortic dissection with flap prolapse into the left ventricle
Rosenzweig BP; Goldstein S; Sherrid M; Kronzon I
1996 Jan 15;77(2):214-216, American journal of cardiology
Transesophageal echocardiography provided an accurate diagnosis of intimal flap prolapse into the left ventricle in all 6 of our patients. This complication of AD is a newly recognized and uncommonly discerned cause of severe AR
— id: 6956, year: 1996, vol: 77, page: 214, stat: Journal Article,

Transesophageal Echocardiography in the Evaluation of Aortic Trauma
Rosenzweig BP; Guarneri E
1996 Mar;13(2):247-258, Echocardiography
Transesophageal echocardiography (TEE) is superior to other imaging techniques for the diagnosis of aortic trauma. It can accurately, rapidly, and safely diagnose life-threatening conditions such as aortic rupture, pseudoaneurysm, traumatic aortic dissection, and intramural hematoma. TEE is useful for the diagnosis and prevention of iatrogenic aortic trauma induced by cardiovascular surgery, intraaortic procedures, and cardiopulmonary resuscitation. (ECHOCARDIOGRAPHY, Volume 13, March 1996)
— id: 94510, year: 1996, vol: 13, page: 247, stat: Journal Article,

Transesophageal echocardiographic diagnosis of right atrial thrombi associated with the antiphospholipid syndrome
Day SM; Rosenzweig BP; Kronzon I
1995 Nov-Dec;8(6):937-940, Journal of the American Society of Echocardiography
Thromboembolic disorders are a hallmark of the antiphospholipid antibody syndrome. We describe a patient with IgM antiphospholipid antibodies associated with pulmonary emboli and in situ thrombosis within an otherwise normal right atrium. Echocardiography, particularly the transesophageal study, proved invaluable in providing a diagnosis and guiding our patient's evaluation and treatment
— id: 11475, year: 1995, vol: 8, page: 937, stat: Journal Article,

DIASTOLIC LEFT-TO-RIGHT SHUNTING IN UNCOMPLICATED VENTRICULAR SEPTAL-DEFECT
KRONZON, I; CZINER, DG; ROSENZWEIG, BP; TUNICK, PA
1995 SEP ;12(5):457-463, Echocardiography
The systolic left-to-right shunt in patients with uncomplicated ventricular septal defect is associated with a classic loud murmur, and is well described. The additional diastolic left-to-right shunt, always silent, is less well recognized. Left-to-right diastolic shunt flow is directly related to the defect size, to the diastolic pressure gradient between. the left and right ventricle, and to the duration of diastole. The purpose of this study was to evaluate by Doppler echocardiography the duration, magnitude, and flow velocity characteristics of the diastolic left-to-right shunt. There were 30 adult patients with uncomplicated ventricular septal defects studied by color, pulsed, and continuous wave Doppler echocardiography. In each patient, the uncomplicated ventricular septal defect was visualized by two-dimensional echocardiography and/or Doppler echocardiography, and the systolic and diastolic left-to-right shunt flow was identified by Doppler echocardiography. Accurate Doppler flow velocity peas twice, in beginning and again. at end diastole. The mean diastolic flow velocity was 0.5-1.5 msec (average 0.83 +/- 22 msec). This flow velocity was markedly lower than the mean systolic shunt flow velocity (2.4-5.3 msec, average 3.8 +/- .7 msec). The Doppler flow velocity integral was 0.17-0.64 m (average 0.36 +/- 0.14), markedly smaller than the systolic flow velocity integral (0.8-1.8 m, average 1.3 +/- 0.3). The diastolic left-to-right shunt flow teas 12-41% (average 21 +/- 8) of total (systolic and diastolic) shunt flow. In conclusion: Diastolic left-to-right shunts can be identified in all patients with uncomplicated ventricular septal defects, and analyzed in the majority of patients. A significant degree of the left to right shunting in. uncomplicated ventricular septal defects occur during diastole
— id: 86730, year: 1995, vol: 12, page: 457, stat: Journal Article,

Correlates of spontaneous echo contrast in patients with mitral stenosis and normal sinus rhythm
Bernstein NE; Demopoulos LA; Tunick PA; Rosenzweig BP; Kronzon I
1994 Aug;128(2):287-292, American heart journal
The purpose of this study was to evaluate the correlates of spontaneous echo contrast in mitral stenosis and normal sinus rhythm. Spontaneous echo contrast is associated with clot formation and embolic phenomena. It has been noted in conditions involving blood stasis, especially mitral stenosis and atrial fibrillation, but the correlates of spontaneous echo contrast in patients with mitral stenosis and normal sinus rhythm have not been extensively evaluated. The transthoracic and transesophageal echocardiograms and clinical findings of 47 patients with mitral stenosis and normal sinus rhythm were reviewed. Left atrial size, mean transmitral gradient, and valve area were measured, and the presence or absence of spontaneous echo contrast in the left atrium was noted. Spontaneous echo contrast was found in the echocardiograms of 21 (45%, group 1) of 47 patients. There was no contrast in those of the other 26 patients (group 2). Mean transmitral gradient was significantly higher in group 1 (13.6 +/- 5.2 mm Hg) than in group 2 (10.5 +/- 4.9 mm Hg) (p < 0.05). Mitral valve area was significantly smaller in group 1 than in group 2 (1.0 +/- 0.5 vs 1.4 +/- 0.5 cm2; p < 0.02). There was a trend toward a higher prevalence of significant mitral regurgitation in group 2. There was no significant difference with respect to age, left atrial size, history of embolism, or warfarin therapy. We conclude that spontaneous echo contrast in the left atrium of patients with mitral stenosis and normal sinus rhythm is common and is associated with a significantly smaller mitral valve area and higher mitral gradient.(ABSTRACT TRUNCATED AT 250 WORDS)
— id: 12931, year: 1994, vol: 128, page: 287, stat: Journal Article,

Transesophageal echocardiographic diagnosis of the superior vena cava syndrome resulting from aortic dissection: a multiplane study
Rosenzweig BP; Kronzon I
1994 Jul-Aug;7(4):414-418, Journal of the American Society of Echocardiography
The case of an 82-year-old patient with signs and symptoms of superior vena cava syndrome is described. A multiplane transesophageal echocardiogram demonstrated anatomic and Doppler flow evidence of superior vena caval obstruction due to compression by a dissected, aneurysmal ascending aorta. Multiplane transesophageal echocardiography is particularly useful in the diagnosis of superior vena cava syndrome when it is a sequela of thoracic aortic disease
— id: 6732, year: 1994, vol: 7, page: 414, stat: Journal Article,

High risk for vascular events in patients with protruding aortic atheromas: a prospective study
Tunick PA; Rosenzweig BP; Katz ES; Freedberg RS; Perez JL; Kronzon I
1994 Apr;23(5):1085-1090, Journal of the American College of Cardiology
OBJECTIVES. The purpose of this study was to prospectively evaluate the risk of vascular events in patients with protruding aortic atheromas. BACKGROUND. Protruding atheromas of the thoracic aorta have been shown to be associated with embolic disease in previous retrospective studies. METHODS. During a 1-year period, 521 patients had transesophageal echocardiography. Of these, 42 patients had protruding atheromas and no other source of emboli. They were followed up for up to 2 years (mean follow-up 14 months) and compared with a control group without atheromas, matched for age, gender and hypertension. RESULTS. Of 42 patients with atheromas, 14 (33%) had 19 vascular events during follow-up (5 brain, 2 eye, 4 kidney, 1 bowel, 7 lower extremity). Of 42 control patients, 3 (7%) had vascular events (2 brain, 1 eye). Univariate analysis identified only protruding atheromas as significantly correlating with events (p = 0.003). There was no positive correlation of events with age, gender, hypertension, smoking, family history, atrial fibrillation, valve replacement, antithrombotic drug use, diabetes or coronary disease. Multivariate analysis showed that only protruding atheromas independently predicted events (p = 0.005, odds ratio 4.3, 95% confidence interval 1.2 to 15.0). Nine patients died in the atheroma group versus six in the control group, but this was not statistically significant (p = 0.39). CONCLUSIONS. Protruding atheromas seen on transesophageal echocardiography predict future vascular events
— id: 6542, year: 1994, vol: 23, page: 1085, stat: Journal Article,

Echocardiographic manifestations in a patient with pseudoxanthoma elasticum
Rosenzweig BP; Guarneri E; Kronzon I
1993 Sep 15;119(6):487-490, Annals of internal medicine
— id: 13071, year: 1993, vol: 119, page: 487, stat: Journal Article,

Transesophageal versus transthoracic echocardiography for diagnosing mitral valve perforation
Cziner DG; Rosenzweig BP; Katz ES; Keller AM; Daniel WG; Kronzon I
1992 Jun 1;69(17):1495-1497, American journal of cardiology
— id: 13577, year: 1992, vol: 69, page: 1495, stat: Journal Article,

Diagnosis of tumor embolus to the pulmonary artery by transesophageal echocardiography
Katz ES; Rosenzweig BP; Rorman D; Kronzon I
1992 Jul-Aug;5(4):439-443, Journal of the American Society of Echocardiography
This article describes a patient with renal cell carcinoma and massive tumor extension into the inferior vena cava who experienced sudden tachypnea and subsequent cardiopulmonary arrest. Transesophageal echocardiography was used to diagnose a massive tumor embolus to the pulmonary artery that was subsequently confirmed at autopsy. Transesophageal echocardiography provided a rapid bedside diagnosis of this unusual entity in an acutely ill patient. This technique may prove more widely applicable in the evaluation of patients with suspected pulmonary embolus, whether neoplastic or thromboembolic
— id: 13538, year: 1992, vol: 5, page: 439, stat: Journal Article,

Silent maladie de Roger
Rosenzweig BP; Rey MJ; Williams LB; Kronzon I
1992 Jul;102(1):320-322, Chest
A patient with no cardiac murmur was found to have a ventricular septal defect by Doppler echocardiography yet no evidence of pulmonary or right ventricular hypertension. This array of findings is distinctly unusual and appears to be at odds with the clinical teachings concerning small ventricular septal defects
— id: 13525, year: 1992, vol: 102, page: 320, stat: Journal Article,

Multifaceted echocardiographic approach to the diagnosis of a ruptured sinus of Valsalva aneurysm
Katz ES; Cziner DG; Rosenzweig BP; Attubato M; Feit F; Kronzon I
1991 Sep-Oct;4(5):494-498, Journal of the American Society of Echocardiography
— id: 13927, year: 1991, vol: 4, page: 494, stat: Journal Article,

Transesophageal echocardiography is superior to transthoracic echocardiography in the diagnosis of sinus venosus atrial septal defect
Kronzon I; Tunick PA; Freedberg RS; Trehan N; Rosenzweig BP; Schwinger ME
1991 Feb;17(2):537-542, Journal of the American College of Cardiology
The purpose of this study was to compare transthoracic and transesophageal echocardiography in the diagnosis of various types of atrial septal defects. Forty-one adult patients with the clinical diagnosis of atrial septal defect were studied by transthoracic and transesophageal echocardiography (30 women, 11 men; 18 to 81 years of age). Transthoracic echocardiography demonstrated the atrial septal defect in 33 patients (secundum type in 28, primum type in 3 and sinus venosus type in 2). Transesophageal echocardiography demonstrated the defect in all 41 patients. Thus, in 8 (20%) of 41 patients the atrial septal defect was demonstrated by transesophageal and not by transthoracic echocardiography. Six of the eight had a sinus venosus type atrial septal defect; the other two patients had a secundum atrial septal defect (one of these two had a technically poor transthoracic echocardiogram and the other had a small atrial septal defect). Transthoracic echocardiography, therefore, failed to demonstrate the sinus venosus defect in six (75%) of eight patients. An anomalous venous connection associated with the sinus venosus defect was visualized by transesophageal echocardiography in seven of the eight patients but was not seen on transthoracic echocardiography in any patient. Sinus venosus type atrial septal defects are frequently not visualized in adults by conventional transthoracic echocardiography. Transesophageal echocardiography is recommended when an atrial septal defect is clinically suspected but cannot be visualized by transthoracic echocardiography
— id: 14141, year: 1991, vol: 17, page: 537, stat: Journal Article,

Left ventricle-to-ascending aorta communication complicating composite graft repair undetected by aortography: diagnosis by transesophageal echocardiography
Rosenzweig BP; Donahue T; Attubato M; Feit F; Kronzon I
1991 Nov-Dec;4(6):639-644, Journal of the American Society of Echocardiography
A 57-year-old man underwent composite ascending aortic conduit and prosthetic aortic valve repair of a sinus of Valsalva aneurysm. The patient's course was complicated by recurrent aneurysm formation caused by a communication between the left ventricular outflow tract and the ascending aorta outside the conduit. Transesophageal echocardiography documented the anatomic and functional characteristics of this complication, whereas aortography failed to demonstrate them. Findings at surgery confirmed the transesophageal echocardiogram results of a left ventricular outflow tract to aorta communication, a normal prosthetic aortic valve, and an intact distal anastomosis of the conduit with the aorta. Transesophageal echocardiography is a useful modality for the evaluation of composite graft repairs of the aortic valve and ascending aorta
— id: 13856, year: 1991, vol: 4, page: 639, stat: Journal Article,

Comparison of cardiac catheterization and Doppler echocardiography in the decision to operate in aortic and mitral valve disease [see comments]
Slater J; Gindea AJ; Freedberg RS; Chinitz LA; Tunick PA; Rosenzweig BP; Winer HE; Goldfarb A; Perez JL; Glassman E; et al
1991 Apr;17(5):1026-1036, Journal of the American College of Cardiology
Clinical decisions utilizing either Doppler echocardiographic or cardiac catheterization data were compared in adult patients with isolated or combined aortic and mitral valve disease. A clinical decision to operate, not operate or remain uncertain was made by experienced cardiologists given either Doppler echocardiographic or cardiac catheterization data. A prospective evaluation was performed on 189 consecutive patients (mean age 67 years) with valvular heart disease who were being considered for surgical treatment on the basis of clinical information. All patients underwent cardiac catheterization and detailed Doppler echocardiographic examination. Three sets of two cardiologist decision makers who did not know patient identity were given clinical information in combination with either Doppler echocardiographic or cardiac catheterization data. The combination of Doppler echocardiographic and clinical data was considered inadequate for clinical decision making in 21% of patients with aortic and 5% of patients with mitral valve disease. The combination of cardiac catheterization and clinical data was considered inadequate in 2% of patients with aortic and 2% of patients with mitral valve disease. Among the remaining patients, the cardiologists using echocardiographic or angiographic data were in agreement on the decision to operate or not operate in 113 (76% overall). When the data were analyzed by specific valve lesion, decisions based on Doppler echocardiography or catheterization were in agreement in 92%, 90%, 83% and 69%, respectively, of patients with aortic regurgitation, mitral stenosis, aortic stenosis and mitral regurgitation. Differences in cardiac output determination, estimation of valvular regurgitation and information concerning coronary anatomy were the main reasons for different clinical management decisions. These results suggest that for most adult patients with aortic or mitral valve disease, alone or in combination, Doppler echocardiographic data enable the clinician to make the same decision reached with catheterization data
— id: 14079, year: 1991, vol: 17, page: 1026, stat: Journal Article,

Cardiac lymphoma in the acquired immunodeficiency syndrome
Goldfarb A; King CL; Rosenzweig BP; Feit F; Kamat BR; Rumancik WM; Kronzon I
1989 Dec;118(6):1340-1344, American heart journal
— id: 10405, year: 1989, vol: 118, page: 1340, stat: Journal Article,

Mirror-image dextrocardia with failure of apical pivoting ("levocardia") and situs inversus
Rosenzweig BP; Gindea AJ; Lubat E; Danilowicz D; Weinreb J; Kronzon I
1989 Oct;118(4):845-848, American heart journal
— id: 10477, year: 1989, vol: 118, page: 845, stat: Journal Article,

Systolic antegrade tricuspid blood flow--a sign of severe prosthetic valve stenosis
Rosenzweig BP; Kronzon I; Feit F; Stecy PJ; Nachamie MS; Politzer F
1988 Mar;115(3):693-696, American heart journal
— id: 11161, year: 1988, vol: 115, page: 693, stat: Journal Article,

Diagnosis of a large left atrial myxoma: the role of two-dimensional echocardiography
Kronzon, I; Rosenzweig, B; Dack, S
1982 Jan;10(1):39-41, Journal of clinical ultrasound
— id: 100142, year: 1982, vol: 10, page: 39, stat: Journal Article,

Echocardiographic diagnosis of papillary muscle calcification
Rosenzweig, B; Kronzon, I; Newman, P; Gargiulo, A
1982 Sep;10(7):342-344, Journal of clinical ultrasound
— id: 100133, year: 1982, vol: 10, page: 342, stat: Journal Article,

Single channel dual echocardiography
Arditti, A; Rosenzweig, B; Kronzon, I; Sharaz, J; Laniado, S
1980 Aug;46(2):277-280, American journal of cardiology
An inexpensive method for obtaining simultaneous echograms from two or more cardiac areas is described. The measurement of systolic and diastolic time intervals, the identification of various auscultatory findings and the diagnosis of some valvular lesions are among the uses of such a technique
— id: 100149, year: 1980, vol: 46, page: 277, stat: Journal Article,

PROTEIN-KINASES IN CHRONIC LYMPHOCYTIC-LEUKEMIA
Samuel, E; Chung, CH; Scher, N; Rosenzweig, B; Silber, R
1980 ;55(4):618-624, Blood
— id: 27918, year: 1980, vol: 55, page: 618, stat: Journal Article,