Robert Clancy

Biosketch / Results /

Robert Clancy, Ph.D.

Associate Professor;
Departments of Medicine (Rheum Div) and Hospital for Joint Diseases

Contact Info

Address
550 First Avenue
Floor 6 Room 606
Medical Science Building
New York, NY 10016

212-263-0751
Robert.Clancy@nyumc.org

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Research Summary

The interaction between the extracellular matrix and cells affects a wide spectrum of cellular processes including migration, growth, death, capacity to degrade matrix, capacity to synthesize matrix, differentiation, and cell attachment. In human neutrophils, we study signalling by beta1 integrin receptors which contribute to cell attachment and migration. Additionally, we study the effect of nitric oxide, an inflammatory mediator, on the signalling pathways. Neutrophils help destroy foreign invaders at tissue sites but first must reversibly undergo cell attachment through the endothelium and matrix. We hypothesize that nitric oxide modulates matrix-cell interaction by the reversible inhibition of neutrophil attachment to fibronectin (ligand for beta1 integrin)-coated surfaces. We recently showed that nitric oxide inhibits adherence associated with a stimulation of actin-ADP ribosylation. In bovine chondrocytes, we study signalling by beta1 integrin receptors which contribute to the capacity to degrade matrix and differentiation. We hypothesize that nitric oxide, a mediator of arthritis, inhibits chondrocyte adherence and cell capacity to contribute to matrix synthesis and breakdown. Recently, we studied signalling by beta1 integrins in chondrocytes by measuring protein accumulation to contact sites in chondrocytes exposed to fibronectin-coated and albumin-coated beads. Chondrocytes exposed to albumin-coated beads failed to generate a response, but cytoskeletal and signalling molecules accumulated to fibronectin-coated and albumin-coated beads which include polymerized actin, focal adhesion kinase, and the accumulation of tyrosine phosphorylated proteins (see Figure). Prior treatment of chondrocytes with catabolic cytokines (which stimulate nitric oxide synthesis) prevent the response. Collectively, our results suggest that nitric oxide induced a persistently altered chondrocyte phenotype (chondrocytes incapable of signalling via beta 1 integrins) which might be reversed or prevented by using nitric oxide antagonists. A persistently altered state in chondrocytes would greatly change the ability of such chondrocytes to mature and perhaps result in the changes seen in arthritis.

Research Interests

Molecular Mechanism of beta1 Integrin Signal Transduction

Research Keywords

beta1 integrin, chondrocyte, inflammation, neutrophil, nitric oxide, signal transduction

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Letter to the Editor in response to the article "Preventing congenital neonatal heart block in offspring of mothers with anti-SSA/Ro and SSB/La antibodies: A review of published literature and registered clinical trials." by Gleicher N, Elkayam U, Autoimmun Rev. 2013 Sep;12(11):1039-45
Costedoat-Chalumeau, Nathalie; Izmirly, Peter; Wahren-Herlenius, Marie; Silverman, Earl; Brucato, Antonio; Boutjdir, Mohamed; Khamashta, Munther; Llanos, Carolina; Pisoni, Cecilia N; Friedman, Deborah M; Clancy, Robert; Phoon, Colin K L; Saxena, Amit; Buyon, Jill P
2014 Jan;13(1):70-72, Autoimmunity reviews
— id: 628742, year: 2014, vol: 13, page: 70, stat: Journal Article,

Relation of carotid plaque with natural IgM antibodies in patients with systemic lupus erythematosus
Gronwall, Caroline; Reynolds, Harmony; Kim, June K; Buyon, Jill; Goldberg, Judith D; Clancy, Robert M; Silverman, Gregg J
2014 Apr;153(1):1-7, Clinical immunology
— id: 960172, year: 2014, vol: 153, page: 1, stat: Journal Article,

A central role of plasmin in cardiac injury initiated by fetal exposure to maternal anti-Ro autoantibodies
Briassouli, Paraskevi; Halushka, Marc K; Reed, Joanne H; Molad, Yair; Fox-Talbot, Karen; Buyon, Lucas; Guzman, Edwin; Ludomirsky, Achiau; Clancy, Robert M; Buyon, Jill P
2013 Aug;52(8):1448-1453, Rheumatology (Oxford)
— id: 438782, year: 2013, vol: 52, page: 1448, stat: Journal Article,

ITGAM R77H: Genotype/Phenotype relationships in toll-like receptor 7 stimulated macrophages
Clancy, R; Reed, J R; Lee, K; Jain, M; Gupta, V; Buyon, J P
2013 March 2013;22(1):25-25, Lupus
— id: 558112, year: 2013, vol: 22, page: 25, stat: Journal Article,

Accounting For Parental Load and Identification Of Multiple Risk Variants For Anti-Ro Congenital Heart Block Through High-Density Genotyping Of Immune-Related Loci
Clancy, Robert M. ; Buyon, Jill P. ; Costedoat-Chalumeau, Nathalie ; Brucato, Antonio ; Levesque, Kateri ; Ramoni, Veronique ; Marion, Miranda C. ; Comeau, Mary ; Sajuthi, Satria ; Ramos, Paula S. ; Kimberly, Robert P. ; Howard, Timothy D. ; Langefeld, Carl D.
2013 OCT;65 10 10(SI):S1226-S1226, Arthritis & rheumatism
— id: 656372, year: 2013, vol: 65 10 10, page: S1226, stat: Journal Article,

Active systemic lupus erythematosus is associated with decreased blood conventional dendritic cells
Khan, Shaukat Ali; Nowatzky, Johannes; Jimenez-Branda, Sonia; Greenberg, Jeffrey David; Clancy, Robert; Buyon, Jill; Bhardwaj, Nina
2013 Jun;95(2):121-123, Experimental & molecular pathology
— id: 509642, year: 2013, vol: 95, page: 121, stat: Journal Article,

Increased Expression Of Membrane Endothelial Protein C Receptor Associates With Poor Response In Lupus Nephritis Independent Of Chronicity Index
Mendez, Barbara ; Wu, Ming ; Santoriello, Dominick ; Barisoni, Laura ; Izmirly, Peter M. ; Buyon, Jill P. ; Clancy, Robert M.
2013 OCT;65 10 10(SI):S264-S264, Arthritis & rheumatism
— id: 657202, year: 2013, vol: 65 10 10, page: S264, stat: Journal Article,

Complement Receptor 3 Influences Toll-like Receptor 7/8-Dependent Inflammation: IMPLICATIONS FOR AUTOIMMUNE DISEASES CHARACTERIZED BY ANTIBODY REACTIVITY TO RIBONUCLEOPROTEINS
Reed, Joanne H; Jain, Manish; Lee, Kristen; Kandimalla, Ekambar R; Faridi, Mohd Hafeez; Buyon, Jill P; Gupta, Vineet; Clancy, Robert M
2013 Mar;288(13):9077-9083, Journal of biological chemistry
— id: 271242, year: 2013, vol: 288, page: 9077, stat: Journal Article,

Ro60 requires y3 RNA for cell surface exposure and inflammation associated with cardiac manifestations of neonatal lupus
Reed, Joanne H; Sim, Soyeong; Wolin, Sandra L; Clancy, Robert M; Buyon, Jill P
2013 Jul;191(1):110-116, Journal of immunology (1950)
— id: 402182, year: 2013, vol: 191, page: 110, stat: Journal Article,

Endosomal Toll-like receptors protect MyD88 from Complement Receptor 3-mediated degradation
Reed, Joanne; Buyon, Jill; Gupta, Vineet; Clancy, Robert
2013 MAY 1;190:-, Journal of immunology (1950)
— id: 540682, year: 2013, vol: 190, page: , stat: Journal Article,

Identification of risk genes linking inflammation and fibrosis in passively acquired autoimmune disease
Reed, Joanne; Clancy, Robert; Zavadil, Jiri; Buyon, Jill
2013 MAY 1;190:-, Journal of immunology (1950)
— id: 540692, year: 2013, vol: 190, page: , stat: Journal Article,

Maternal Vitamin D, Fetal C-Reactive Protein and Brain Natriuretic Peptide Associate With The Development and Morbidity Of Cardiac Neonatal Lupus
Saxena, Amit ; Izmirly, Peter M. ; Reed, Joanne H. ; Sahl, Sara ; Friedman, Deborah ; Clancy, Robert M. ; Buyon, Jill P.
2013 OCT;65 10 10(SI):S538-S538, Arthritis & rheumatism
— id: 657582, year: 2013, vol: 65 10 10, page: S538, stat: Journal Article,

Anti-SSA/Ro Mediated Injury to the Endothelium Via Urokinase Plasminogen Activator Receptor/Tgfbeta Activation: Implications in the Pathogenesis of Congenital Heart Block
Briasouli, Paraskevi; Halushka, Mark; Buyon, Jill P.; Clancy, Robert M.
2012 OCT;64(10 S S):S759-S759, Arthritis & rheumatism
— id: 183942, year: 2012, vol: 64, page: S759, stat: Journal Article,

Brief Report: IRF5 systemic lupus erythematosus risk haplotype is associated with asymptomatic serologic autoimmunity and progression to clinical autoimmunity in mothers of children with neonatal lupus
Cherian, Tharian S; Kariuki, Silvia N; Franek, Beverly S; Buyon, Jill P; Clancy, Robert M; Niewold, Timothy B
2012 Oct;64(10):3383-3387, Arthritis & rheumatism
— id: 182212, year: 2012, vol: 64, page: 3383, stat: Journal Article,

Dysregulation of the Microvasculature in Nonlesional Non-Sun-exposed Skin of Patients with Lupus Nephritis
Izmirly, Peter M; Shvartsbeyn, Marianna; Meehan, Shane; Franks, Andrew; Braun, Alan; Ginzler, Ellen; Xu, Sherry X; Yee, Herman; Rivera, Tania; Esmon, Charles; Barisoni, Laura; Merrill, Joan T; Buyon, Jill P; Clancy, Robert M
2012 Mar;39(3):510-515, Journal of rheumatology
— id: 159836, year: 2012, vol: 39, page: 510, stat: Journal Article,

Leukadherin 1, a CR3 Mimetic, Negatively Regulates Toll Like Receptor (TLR) Dependent Inflammatory Responses via Degradation of an Adaptor Protein
Lee, Kristen; Reed, Joanne H.; Gupta, Vineet; Patel, Tejaskumar; Buyon, Jill P.; Clancy, Robert M.
2012 OCT;64(10 S S):S287-S287, Arthritis & rheumatism
— id: 183982, year: 2012, vol: 64, page: S287, stat: Journal Article,

Anatomical and pathological findings in hearts from fetuses and infants with cardiac manifestations of neonatal lupus
Llanos, C; Friedman, DM; Saxena, A; Izmirly, PM; Tseng, CE; Dische, R; Abellar, RG; Halushka, M; Clancy, RM; Buyon, JP
2012 Feb;:1086-1092, Rheumatology (Oxford)
— id: 161068, year: 2012, vol: , page: 1086, stat: Journal Article,

Epigenetic Changes in Fibrosis and Myocyte Repair Genes May Contribute to Pathogenesis in Monozygotic Twins Discordant for Cardiac Manifestations of Neonatal Lupus
Ramos, Paula S.; Howard, Timothy D.; Marion, Miranda C.; Sajuthi, Satria; Clancy, Robert M.; Buyon, Jill P.; Langefeld, Carl D.
2012 OCT;64(10 S S):S137-S137, Arthritis & rheumatism
— id: 184052, year: 2012, vol: 64, page: S137, stat: Journal Article,

Brief Report: Enrichment of associations in genes with fibrosis, apoptosis, and innate immunity functions with cardiac manifestations of neonatal lupus
Ramos, Paula S; Marion, Miranda C; Langefeld, Carl D; Buyon, Jill P; Clancy, Robert M
2012 Dec;64(12):4060-4065, Arthritis & rheumatism
— id: 210232, year: 2012, vol: 64, page: 4060, stat: Journal Article,

Modeling Environmental and Genetic Determinants to Identify the Association of Risk Genes in Anti-Ro60-Mediated Injury: Relaxin Receptor I and Tumor Necrosis Factor
Reed, Joanne H.; Ramos, Paula S.; Zavadil, Jiri; Buyon, Jill P.; Clancy, Robert M.
2012 OCT;64(10 S S):S387-S387, Arthritis & rheumatism
— id: 184162, year: 2012, vol: 64, page: S387, stat: Journal Article,

Umbilical cord blood levels of maternal antibodies reactive with p200 and full-length Ro 52 in the assessment of risk for cardiac manifestations of neonatal lupus
Reed, Joanne H; Clancy, Robert M; Lee, Kristen H; Saxena, Amit; Izmirly, Peter M; Buyon, Jill P
2012 Sep;64(9):1373-1381, Arthritis care & research (2010)
— id: 177017, year: 2012, vol: 64, page: 1373, stat: Journal Article,

Preferential transmission of genetic risk variants of candidate loci at 6p21 from asymptomatic grandparents to mothers of children with neonatal lupus
Saxena, Amit; McDonnell, Erin; Ramos, Paula S; Sajuthi, Satria; Marion, Miranda C; Langefeld, Carl D; Buyon, Jill P; Clancy, Robert M
2012 Mar;64(3):931-939, Arthritis & rheumatism
— id: 158264, year: 2012, vol: 64, page: 931, stat: Journal Article,

Response to MMF Therapy for Lupus Nephritis Is Independent of Genetic Variation of Inosine Monophosphate Dehydrogenase
Schwartz, Noa; Patel, Tejaskumar; Ginzler, Ellen M.; Solomons, Neil; Buyon, Jill P.; Clancy, Robert M.
2012 OCT;64(10 S S):S365-S365, Arthritis & rheumatism
— id: 183832, year: 2012, vol: 64, page: S365, stat: Journal Article,

A Novel Role of Endothelin-1 in Linking Toll-like Receptor 7-mediated Inflammation to Fibrosis in Congenital Heart Block
Alvarez, David; Briassouli, Paraskevi; Clancy, Robert M; Zavadil, Jiri; Reed, Joanne H; Abellar, Rosanna G; Halushka, Marc; Fox-Talbot, Karen; Barrat, Franck J; Buyon, Jill P
2011 Sep 2;286(35):30444-30454, Journal of biological chemistry
— id: 136998, year: 2011, vol: 286, page: 30444, stat: Journal Article,

Binding of Anti-SSA Antibodies to Apoptotic Fetal Cardiocytes Stimulates Urokinase Plasminogen Activator (uPA)/uPA Receptor-Dependent Activation of TGF-beta and Potentiates Fibrosis
Briassouli, Paraskevi; Rifkin, Daniel; Clancy, Robert M; Buyon, Jill P
2011 Nov 15;187(10):5392-5401, Journal of immunology (1950)
— id: 140530, year: 2011, vol: 187, page: 5392, stat: Journal Article,

{beta}2-Glycoprotein I and Protection from Anti-SSA/Ro60-Associated Cardiac Manifestations of Neonatal Lupus
Reed, Joanne H; Clancy, Robert M; Purcell, Anthony W; Kim, Mimi Y; Gordon, Tom P; Buyon, Jill P
2011 Jul 1;187(1):520-526, Journal of immunology (1950)
— id: 134451, year: 2011, vol: 187, page: 520, stat: Journal Article,

Association of the idiotype:antiidiotype antibody ratio with the efficacy of intravenous immunoglobulin treatment for the prevention of recurrent autoimmune-associated congenital heart block
Routsias, John G; Kyriakidis, Nikolaos C; Friedman, Deborah M; Llanos, Carolina; Clancy, Robert; Moutsopoulos, Haralampos M; Buyon, Jill; Tzioufas, Athanasios G
2011 Sep;63(9):2783-2789, Arthritis & rheumatism
— id: 845762, year: 2011, vol: 63, page: 2783, stat: Journal Article,

A novel role of endothelin-1 in linking Ro60-ssRNA immune complexes to cardiac fibrosis in congenital heart block
Alvarez-Carbonell D.; Zavadil J.; Abellar R.; Barrat F.; Clancy R.; Buyon J.
2010 ;62:2231-2231, Arthritis & rheumatism
— id: 130921, year: 2010, vol: 62, page: 2231, stat: Journal Article,

Binding of apoptotic fetal cardiocytes by anti-Ro/La antibodies stimulates uPA/uPAR-dependent activation of TGFbeta and potentiates fibrosis
Briassouli P.; Rifkin D.; Buyon J.P.; Clancy R.M.
2010 ;62:489-489, Arthritis & rheumatism
— id: 130926, year: 2010, vol: 62, page: 489, stat: Journal Article,

Role of the Urokinase Plasminogen Activator Receptor in Mediating Impaired Efferocytosis of Anti-SSA/Ro-Bound Apoptotic Cardiocytes: Implications in the Pathogenesis of Congenital Heart Block
Briassouli, Paraskevi; Komissarova, Elena V; Clancy, Robert M; Buyon, Jill P
2010 Aug 6;107(3):374-387, Circulation research
— id: 111585, year: 2010, vol: 107, page: 374, stat: Journal Article,

Passively acquired anti-SSA/Ro antibodies are required for congenital heart block following ovodonation but maternal genes are not
Brucato, Antonio; Ramoni, Veronique; Penco, Silvana; Sala, Elena; Buyon, Jill; Clancy, Robert
2010 Oct;62(10):3119-3121, Arthritis & rheumatism
— id: 120803, year: 2010, vol: 62, page: 3119, stat: Journal Article,

Genome-wide association study of cardiac manifestations of neonatal lupus identifies risk variants in the ERG, TCF19,C6orf10 and MICB-TNF-AIF1 region
Clancy R.; Marion M.C.; Kaufman K.M.; Ramos P.S.; Adler A.; Harley J.B.; Langefeld C.D.; Buyon J.P.
2010 ;19:21-21, Lupus
— id: 134746, year: 2010, vol: 19, page: 21, stat: Journal Article,

Ro60-Associated Single-Stranded RNA Links Inflammation with Fetal Cardiac Fibrosis via Ligation of TLRs: A Novel Pathway to Autoimmune-Associated Heart Block
Clancy, Robert M; Alvarez, David; Komissarova, Elena; Barrat, Franck J; Swartz, Jordan; Buyon, Jill P
2010 Feb 15;184(4):2148-2155, Journal of immunology (1950)
— id: 106500, year: 2010, vol: 184, page: 2148, stat: Journal Article,

Identification of candidate loci at 6p21 and 21q22 in a genome-wide association study of cardiac manifestations of neonatal lupus
Clancy, Robert M; Marion, Miranda C; Kaufman, Kenneth M; Ramos, Paula S; Adler, Adam; Harley, John B; Langefeld, Carl D; Buyon, Jill P
2010 Nov;62(11):3415-3424, Arthritis & rheumatism
— id: 114171, year: 2010, vol: 62, page: 3415, stat: Journal Article,

Endothelial function and its implications for cardiovascular and renal disease in systemic lupus erythematosus
Clancy, Robert; Ginzler, Ellen M
2010 Feb;36(1):295-308, Rheumatic diseases clinics of North America
— id: 108430, year: 2010, vol: 36, page: 295, stat: Journal Article,

Dysregulation of the microvascular as assessed by expression of protective and injury associated markers is reflected in the non-lesional non-sunexposed skin of patients with lupus nephritis
Izmirly P.M.; Meehan S.; Xu S.X.; Askanase A.D.; Merrill J.T.; Buyon J.P.; Clancy R.M.
2010 ;62:1190-1190, Arthritis & rheumatism
— id: 130932, year: 2010, vol: 62, page: 1190, stat: Journal Article,

Congenital heart block: identification of autoantibody binding site on the extracellular loop (domain I, S5-S6) of alpha(1D) L-type Ca channel
Karnabi, Eddy; Qu, Yongxia; Wadgaonkar, Raj; Mancarella, Salvatore; Yue, Yuankun; Chahine, Mohamed; Clancy, Robert M; Buyon, Jill P; Boutjdir, Mohamed
2010 Mar;34(2):80-86, Journal of autoimmunity
— id: 114633, year: 2010, vol: 34, page: 80, stat: Journal Article,

Anatomic and Pathologic Findings in Hearts from Fetuses and Infants with Cardiac Manifestations of Neonatal Lupus
Llanos, C; Clancy, RM; Abellar, R; Buyon, JP; Friedman, DM
2010 SEP ;72(3):270-271, Scandinavian journal of immunology
— id: 111795, year: 2010, vol: 72, page: 270, stat: Journal Article,

IRF5 SLE-risk haplotype is strongly enriched in anti-Ro positive mothers of Neonatal lupus patients with diverse diagnoses
Niewold T.B.; Kariuki S.N.; Franek B.S.; Buyon J.P.; Clancy R.M.
2010 ;62:495-495, Arthritis & rheumatism
— id: 130941, year: 2010, vol: 62, page: 495, stat: Journal Article,

Association of plasma soluble E-selectin and adiponectin with carotid plaque in patients with systemic lupus erythematosus
Reynolds, Harmony R; Buyon, Jill; Kim, Mimi; Rivera, Tania L; Izmirly, Peter; Tunick, Paul; Clancy, Robert M
2010 Jun;210(2):569-574, Atherosclerosis
— id: 109844, year: 2010, vol: 210, page: 569, stat: Journal Article,

IVIG Administration Enhances the Anti-Idiotypic Response to the Major Epitope Of La/SSB Autoantigen in Pregnant Women at High Risk for a Child with Chb
Routsias, JG; Kyriakidis, N; Friedman, D; Llanos, C; Clancy, R; Buyon, J; Tzioufas, AG
2010 SEP ;72(3):272-272, Scandinavian journal of immunology
— id: 111796, year: 2010, vol: 72, page: 272, stat: Journal Article,

Widespread upregulation of mEPCR in kidney, spleen and liver of a nephritic NZM B/W f1: Implications to microvascular disease
Xu S.; Clancy R.M.
2010 ;62:443-443, Arthritis & rheumatism
— id: 130950, year: 2010, vol: 62, page: 443, stat: Journal Article,

Ro60 associated ssRNA links inflammation with fetal cardiac fibrosis via ligation of toll like receptors: A potential pathway to heart block
Alvarez D.; Komissarova E.V.; Swartz J.; BarraT F.; Rivera T.L.; Clancy R.M.; Buyon J.P.
2009 ;60:127-127, Arthritis & rheumatism
— id: 130343, year: 2009, vol: 60, page: 127, stat: Journal Article,

Congenital heart block (CHB) after ovodonation
Brucato, A; Clancy, RM; Ramoni, V; Borghi, A; Sadou, Y; Pisoni, MP; Buyon, JP
2009 AUG 8 ;139(31-32):15S-15S, Swiss medical weekly
— id: 101608, year: 2009, vol: 139, page: 15S, stat: Journal Article,

Autoimmune associated congenital heart block: integration of clinical and research clues in the management of the maternal / foetal dyad at risk
Buyon, J P; Clancy, R M; Friedman, D M
2009 Jun;265(6):653-662, Journal of internal medicine
— id: 99251, year: 2009, vol: 265, page: 653, stat: Journal Article,

Cardiac manifestations of neonatal lupus erythematosus: guidelines to management, integrating clues from the bench and bedside
Buyon, Jill P; Clancy, Robert M; Friedman, Deborah M
2009 Mar;5(3):139-148, Nature clinical practice. Rheumatology
— id: 94462, year: 2009, vol: 5, page: 139, stat: Journal Article,

Association of adiponectin and soluble endothelial protein C receptor (sEPCR) with longitudinal assessments in the induction phase of a randomized multicenter trial comparing mycophenalate mofetil and intravenous cyclophosphamide
Clancy R.M.; Ginzler E.M.; Kim M.
2009 ;60:263-263, Arthritis & rheumatism
— id: 130317, year: 2009, vol: 60, page: 263, stat: Journal Article,

Towards genetic correlates of cardiac manifestations of neonatal lupus: A genome-wide association study
Clancy R.M.; Marion M.C.; Kaufman K.M.; Adler A.; Harley J.B.; Langefeld C.D.; Buyon J.P.
2009 ;60:1230-1230, Arthritis & rheumatism
— id: 130347, year: 2009, vol: 60, page: 1230, stat: Journal Article,

When the levee doesn't break: A novel role of beta(2)-glycoprotein I to protect against congenital heart block
Clancy, Robert M
2009 Mar;60(3):636-638, Arthritis & rheumatism
— id: 94463, year: 2009, vol: 60, page: 636, stat: Journal Article,

Anatomic and Pathologic Findings in Hearts From Fetuses and Infants With Cardiac Manifestations of Neonatal Lupus
Friedman, DM; Llanos, C; Izmirly, PM; Clancy, RM; Buyon, JP
2009 NOV 3 ;120(18):S578-S578, Circulation
— id: 106972, year: 2009, vol: 120, page: S578, stat: Journal Article,

Association of soluble E-selectin and adiponectin with carotid plaque, independent of clinical activity, in patients with systemic lupus erythematosus
Izmirly P.M.; Reynolds H.R.; Rivera T.L.; Kim M.Y.; Tunick P.A.; Buyon J.P.; Clancy R.M.
2009 ;60:1562-1562, Arthritis & rheumatism
— id: 130319, year: 2009, vol: 60, page: 1562, stat: Journal Article,

Expression of endothelial protein C receptor in cortical peritubular capillaries associates with a poor clinical response in lupus nephritis
Izmirly, Peter M; Barisoni, Laura; Buyon, Jill P; Kim, Mimi Y; Rivera, Tania L; Schwartzman, Julie S; Weisstuch, Joseph M; Liu, David T; Bernstein, Stephen; Tseng, Chung-E; Belmont, Howard M; Esmon, Charles T; Merrill, Joan T; Askanase, Anca D; Thomas, David B; Clancy, Robert M
2009 May;48(5):513-519, Rheumatology (Oxford)
— id: 100419, year: 2009, vol: 48, page: 513, stat: Journal Article,

Modulation of TLR7 and TLR8 activation in human macrophages
Komissarova E.V.; Kandimalla E.R.; Agrawal S.; Clancy R.M.; Buyon J.P.
2009 ;60:141-141, Arthritis & rheumatism
— id: 130333, year: 2009, vol: 60, page: 141, stat: Journal Article,

Antibody Reactivity to {alpha}-Enolase in Mothers of Children with Congenital Heart Block
Llanos, Carolina; Chan, Edward K L; Li, Songqing; Abadal, Grant X; Izmirly, Peter; Byrne, Caroline; Clancy, Robert M; Buyon, Jill P
2009 Mar;36(3):565-569, Journal of rheumatology
— id: 94464, year: 2009, vol: 36, page: 565, stat: Journal Article,

Recurrence rates of cardiac manifestations associated with neonatal lupus and maternal/fetal risk factors
Llanos, Carolina; Izmirly, Peter M; Katholi, Margaret; Clancy, Robert M; Friedman, Deborah M; Kim, Mimi Y; Buyon, Jill P
2009 Oct;60(10):3091-3097, Arthritis & rheumatism
— id: 104348, year: 2009, vol: 60, page: 3091, stat: Journal Article,

Two single nucleotide polymorphisms (SNPS) in the endothelial protein C receptor (EPCR) gene are associated with lower soluble EPCR (sEPCR). Low complement C4 and thrombotic risk in patients with lupus (SLE)
Merrill J.T.; Clancy R.M.; Kamp S.; Thomas K.; Woodhams B.; Esmon N.L.
2009 ;60:1745-1745, Arthritis & rheumatism
— id: 130348, year: 2009, vol: 60, page: 1745, stat: Journal Article,

Disease progression in mothers of children enrolled in the Research Registry for Neonatal Lupus
Rivera, T L; Izmirly, P M; Birnbaum, B K; Byrne, P; Brauth, J B; Katholi, M; Kim, M Y; Fischer, J; Clancy, R M; Buyon, J P
2009 Jun;68(6):828-835, Annals of rheumatic diseases
— id: 94465, year: 2009, vol: 68, page: 828, stat: Journal Article,

Longitudinal evaluation of idiotypic and anti-idiotypic response to the major epitope of La/SSB autoantigen in mothers enrolled in the PITCH (Preventive IVIG Therapy for Congenital Heart Block) study
Routsias Jg.; Kyriakidis N.; Llanos C.; Clancy R.M.; Buyon J.; Tzioufas A.G.
2009 ;60:1586-1586, Arthritis & rheumatism
— id: 130332, year: 2009, vol: 60, page: 1586, stat: Journal Article,

Dying right to live longer: positing apoptosis as a link between maternal autoantibodies and congenital heart block
Buyon, J P; Clancy, R M
2008 ;17(2):86-90, Lupus
— id: 78688, year: 2008, vol: 17, page: 86, stat: Journal Article,

Decreased risk of anti-Ro/La associated congenital heart (CHB) in fetuses exposed to hydroxychloroquine (HCQ)
Izinirly, P; Kim, M; Le, P; Llanos, C; Katholi, M; Clancy, R; Salmon, J; Buyon, J
2008 SEP ;58(9):S810-S810, Arthritis & rheumatism
— id: 88572, year: 2008, vol: 58, page: S810, stat: Journal Article,

Widespread Upregulation of membrane endothelial protein c receptor in a subset of patients with active lupus nephritis
Izmirly, P; Yee, H; Rivera, T; Belmont, HM; Tseng, CE; Esmon, C; Braun, A; Askanase, A; Ginzler, EM; Buyon, J; Clancy, R
2008 SEP ;58(9):S950-S950, Arthritis & rheumatism
— id: 88579, year: 2008, vol: 58, page: S950, stat: Journal Article,

Pregnancy outcomes subsequent to a child with autoimmune associated congenital heart block (CHB) and associated fetal/maternal risk factors
Llanos, C; Izmirly, P; Katholi, M; Edberg, JC; Kimberly, RP; Clancy, R; Buyon, J
2008 SEP ;58(9):S873-S873, Arthritis & rheumatism
— id: 88575, year: 2008, vol: 58, page: S873, stat: Journal Article,

Longitudinal evaluation of anti-La idiotypic antibodies in mothers enrolled in the PITCH study
Routsias, J; Stea, E; Geffrard, L; Friedman, D; Llanos, C; Clancy, RC; Buyon, J; Tzioufas, AG
2008 SEP ;58(9):S804-S804, Arthritis & rheumatism
— id: 88571, year: 2008, vol: 58, page: S804, stat: Journal Article,

Neonatal lupus
Buyon, Jill P; Clancy, Robert M
Dubois' Lupus Erythematosus Philadelphia : Lippincott Williams & Wilkins, 2007,
— id: 4872, year: 2007, vol: , page: ?, stat: Chapter,

Antibodies to SSA/Ro and SSB/La : potential mechanisms of tissue injury in neonatal lupus-congential heart block
Buyon, JP; Clancy, RM
Systemic lupus erythematosus Philadelphia : Mosby Elsevier, c2007,
— id: 603082, year: 2007, vol: , page: 248, stat: Chapter,

Role of hypoxia and cAMP in the transdifferentiation of human fetal cardiac fibroblasts: implications for progression to scarring in autoimmune-associated congenital heart block
Clancy, Robert M; Zheng, Ping; O'Mahony, Marguerita; Izmirly, Peter; Zavadil, Jiri; Gardner, Lawrence; Buyon, Jill P
2007 Dec;56(12):4120-4131, Arthritis & rheumatism
— id: 75771, year: 2007, vol: 56, page: 4120, stat: Journal Article,

Different temporal expression of immunodominant Ro60/60 kDa-SSA and La/SSB apotopes
Reed, J H; Neufing, P J; Jackson, M W; Clancy, R M; Macardle, P J; Buyon, J P; Gordon, T P
2007 Apr;148(1):153-160, Clinical & experimental immunology
— id: 73543, year: 2007, vol: 148, page: 153, stat: Journal Article,

Impaired clearance of apoptotic cardiocytes and the pathogenesis of congenital heart block (CHB): Link to Anti-SSA/Ro-SSB/La antibodies
Clancy, RM; Neufing, PJ; O'Mahony, M; Zheng, P; Llanos, C; Gordon, TP; Buyon, JP
2006 SEP ;54(9):S551-S551, Arthritis & rheumatism
— id: 70126, year: 2006, vol: 54, page: S551, stat: Journal Article,

Preventing and repairing vascular damage in scleroderma: should we focus beyond vasodilatation to recruitment of endothelial precursor cells?
Clancy, Robert M
2006 Jun;54(6):1730-1732, Arthritis & rheumatism
— id: 67281, year: 2006, vol: 54, page: 1730, stat: Journal Article,

Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block
Clancy, Robert M; Neufing, Petra J; Zheng, Ping; O'Mahony, Marguerita; Nimmerjahn, Falk; Gordon, Tom P; Buyon, Jill P
2006 Sep;116(9):2413-2422, Journal of clinical investigation
— id: 67279, year: 2006, vol: 116, page: 2413, stat: Journal Article,

TGF beta, a strong fetal genetic candidate, in the development of congenital heart block (CHB)
Izmirly, PM; Harris, RR; Merrill, JT; Harley, JB; Backer, C; Clancy, RM; Buyon, JP
2006 SEP ;54(9):S536-S537, Arthritis & rheumatism
— id: 70124, year: 2006, vol: 54, page: S536, stat: Journal Article,

Antibody cross-reactivity of ScFv fragments that specifically recognize human apoptotic fetal cardiocytes and recombinant human Ro60
Llanos, C; Buyon, JP; Bennett, S; Lavner, L; Clancy, RM
2006 SEP ;54(9):S67-S68, Arthritis & rheumatism
— id: 70101, year: 2006, vol: 54, page: S67, stat: Journal Article,

Contribution of vasculopathy to lupus nephritis: Endothelial protein C receptor levels and genotype
Rivera, TL; Izmirly, PM; Buyon, JP; Clancy, RM
2006 SEP ;54(9):S824-S825, Arthritis & rheumatism
— id: 70137, year: 2006, vol: 54, page: S824, stat: Journal Article,

Inadequate anti-idiotypic response, as assessed by antibodies to La/SSB complementary epitopes: A novel component in the development of neonatal lupus
Stea, EA; Routsias, JG; Clancy, RM; Buyon, JP; Moutsopoulos, HM; Tzioufas, AG
2006 APR ;65(4):A18-A18, Annals of rheumatic diseases
— id: 74152, year: 2006, vol: 65, page: A18, stat: Journal Article,

Anti-La/SSB antiidiotypic antibodies in maternal serum: a marker of low risk for neonatal lupus in an offspring
Stea, Eleni A; Routsias, John G; Clancy, Robert M; Buyon, Jill P; Moutsopoulos, Haralampos M; Tzioufas, Athanasios G
2006 Jul;54(7):2228-2234, Arthritis & rheumatism
— id: 67280, year: 2006, vol: 54, page: 2228, stat: Journal Article,

Circulating endothelial cells. Biomarker of vascular disease
Blann, Andrew D; Woywodt, Alexander; Bertolini, Francesco; Bull, Todd M; Buyon, Jill P; Clancy, Robert M; Haubitz, Marion; Hebbel, Robert P; Lip, Gregory Y H; Mancuso, Patrizia; Sampol, Jose; Solovey, Anna; Dignat-George, Francoise
2005 Feb;93(2):228-235, Thrombosis & haemostasis
— id: 73527, year: 2005, vol: 93, page: 228, stat: Journal Article,

Autoantibody-associated congenital heart block: TGFbeta and the road to scar
Buyon, Jill P; Clancy, Robert M
2005 Jan;4(1):1-7, Autoimmunity reviews
— id: 55784, year: 2005, vol: 4, page: 1, stat: Journal Article,

Neonatal lupus: basic research and clinical perspectives
Buyon, Jill P; Clancy, Robert M
2005 May;31(2):110-120, Rheumatic diseases clinics of North America
— id: 55992, year: 2005, vol: 31, page: 110, stat: Journal Article,

Reply
Clancy RM; Buyon JP
2005 May;52(5):1625-1626, Arthritis & rheumatism
— id: 55993, year: 2005, vol: 52, page: 1625, stat: Journal Article,

Structure/function of apoptotic pathways and subsequent macrophage activation link anti-Ro/La antibodies to the pathogenesis of congenital heart block
Clancy, R; Zheng, P; Buyon, JP
2005 SEP ;52(9):S449-S449, Arthritis & rheumatism
— id: 59283, year: 2005, vol: 52, page: S449, stat: Journal Article,

Hypoxia, an environmental stress, in initiation and progression of the pathologic cascade to congenital heart block
Clancy, R; Zheng, P; Gardner, L; Buyon, JP
2005 SEP ;52(9):S303-S303, Arthritis & rheumatism
— id: 59276, year: 2005, vol: 52, page: S303, stat: Journal Article,

Maternal antibody responses to the 52-kd SSA/RO p200 peptide and the development of fetal conduction defects
Clancy, Robert M; Buyon, Jill P; Ikeda, Keigo; Nozawa, Kazuhisa; Argyle, Dionne A; Friedman, Deborah M; Chan, Edward K L
2005 Oct;52(10):3079-3086, Arthritis & rheumatism
— id: 58889, year: 2005, vol: 52, page: 3079, stat: Journal Article,

Circulating endothelial cells and soluble endothelial protein C receptor predict the presence of carotid plaque in minority SLE patients
Gehrie, ER; Reynolds, HR; Buyon, JP; Clancy, R
2005 SEP ;52(9):S606-S606, Arthritis & rheumatism
— id: 59293, year: 2005, vol: 52, page: S606, stat: Journal Article,

Autoantibodies against the serotoninergic 5-HT4 receptor and congenital heart block: a reassessment
Kamel, Rehab; Eftekhari, Pierre; Clancy, Robert; Buyon, Jill P; Hoebeke, Johan
2005 Aug;25(1):72-76, Journal of autoimmunity
— id: 67283, year: 2005, vol: 25, page: 72, stat: Journal Article,

E-beam-patterned hydrogels to control nanoscale surface bioactivity
Krsko, P; Saaem, I; Clancy, R; Geller, H; Soteropoulos, P; Libera, M
2005 ;6002:- 600201, Proceedings of SPIE (The International Society for Optical Engineering)
— id: 570062, year: 2005, vol: 6002, page: , stat: Journal Article,

Exposure and binding of selected immunodominant La/SSB epitopes on human apoptotic cells
Neufing, Petra J; Clancy, Robert M; Jackson, Michael W; Tran, Hai Bac; Buyon, Jill P; Gordon, Tom P
2005 Dec;52(12):3934-3942, Arthritis & rheumatism
— id: 67282, year: 2005, vol: 52, page: 3934, stat: Journal Article,

Shedding of endothelial protein C receptor contributes to vasculopathy and renal injury in lupus: In vivo and in vitro evidence
Sesin, Carlos A; Yin, Xiaoming; Esmon, Charles T; Buyon, Jill P; Clancy, Robert M
2005 Jul;68(1):110-120, Kidney international
— id: 55991, year: 2005, vol: 68, page: 110, stat: Journal Article,

Neonatal lupus syndromes
Buyon, J P; Rupel, A; Clancy, R M
2004 ;13(9):705-712, Lupus
— id: 47776, year: 2004, vol: 13, page: 705, stat: Journal Article,

Neonatal lupus syndrome: Cause and management
Buyon, JP; Clancy, RM
2004 JUL ;63(3):4-4, Annals of rheumatic diseases
— id: 49056, year: 2004, vol: 63, page: 4, stat: Journal Article,

Nitric oxide sustains nuclear factor kappaB activation in cytokine-stimulated chondrocytes
Clancy, R M; Gomez, P F; Abramson, S B
2004 Aug;12(7):552-558, Osteoarthritis & cartilage
— id: 46153, year: 2004, vol: 12, page: 552, stat: Journal Article,

Autoantibody associated CHB: TGF beta in the pathway from antibody insult to scarring
Clancy, RM
2004 MAR 23 ;18(4):A403-A403, FASEB journal
— id: 46598, year: 2004, vol: 18, page: A403, stat: Journal Article,

Evaluation of Ro52 peptide antibody profiles in a large cohort of anti-Ro plus women whose children have neonatal lupus (NL) or are healthy
Clancy, RM; Nozawa, K; Friedman, D; Buyon, J; Chan, EK
2004 SEP ;50(9):S532-S532, Arthritis & rheumatism
— id: 49050, year: 2004, vol: 50, page: S532, stat: Journal Article,

Antibody cross-reactivity of scFv fragments that specifically recognize human apoptotic fetal cardiocytes with recombinant human ro52
Clancy, RM; Yin, XM; Buyon, J
2004 SEP ;50(9):S209-S209, Arthritis & rheumatism
— id: 49031, year: 2004, vol: 50, page: S209, stat: Journal Article,

Genetic association of cutaneous neonatal lupus with HLA class II and tumor necrosis factor alpha: implications for pathogenesis
Clancy, Robert M; Backer, Chelsea B; Yin, Xiaoming; Chang, Mary Wu; Cohen, Steven R; Lee, Lela A; Buyon, Jill P
2004 Sep;50(8):2598-2603, Arthritis & rheumatism
— id: 46137, year: 2004, vol: 50, page: 2598, stat: Journal Article,

Autoimmune-associated congenital heart block: dissecting the cascade from immunologic insult to relentless fibrosis
Clancy, Robert M; Buyon, Jill P
2004 Oct;280(2):1027-1035, Anatomical record. Part A, Discoveries in molecular, cellular, & evolutionary biology
— id: 48075, year: 2004, vol: 280, page: 1027, stat: Journal Article,

More to death than dying: apoptosis in the pathogenesis of SSA/Ro-SSB/La-associated congenital heart block
Clancy, Robert M; Buyon, Jill P
2004 Sep;30(3):461-470, Rheumatic diseases clinics of North America
— id: 46167, year: 2004, vol: 30, page: 461, stat: Journal Article,

Immunohistologic evidence supports apoptosis, IgG deposition, and novel macrophage/fibroblast crosstalk in the pathologic cascade leading to congenital heart block
Clancy, Robert M; Kapur, Raj P; Molad, Yair; Askanase, Anca Dinu; Buyon, Jill P
2004 Jan;50(1):173-182, Arthritis & rheumatism
— id: 42614, year: 2004, vol: 50, page: 173, stat: Journal Article,

Apheresis with adacolumn in patients with systemic lupus erythematosus (SLE): A pilot study
Merrill, JT; Buyon, JP; Clancy, R; Petri, M; Becker, M; Komatsu, Y; Gustofson, LM; Wang, T
2004 SEP ;50(9):S416-S416, Arthritis & rheumatism
— id: 49046, year: 2004, vol: 50, page: S416, stat: Journal Article,

Regulation of metalloproteinases and NF-kappaB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA
Pillinger, Michael H; Dinsell, Victoria; Apsel, Beth; Tolani, Sonia N; Marjanovic, Nada; Chan, Edwin S L; Gomez, Paul; Clancy, Robert; Chang, Lih-Fan; Abramson, Steven B
2004 Jul;142(6):973-982, British journal of pharmacology
— id: 48069, year: 2004, vol: 142, page: 973, stat: Journal Article,

In vivo and in vitro evidence that shedding of endothelial protein c receptors (EPCR) contributes to the pathogenesis of SLE
Sesin, C; Yin, X; Buyon, J; Clancy, R
2004 SEP ;50(9):S647-S648, Arthritis & rheumatism
— id: 49052, year: 2004, vol: 50, page: S647, stat: Journal Article,

Development of systemic lupus erythematosus in a patient with congenital heart block - Reply
Askanase, AD; Clancy, RM; Buyon, JP
2003 SEP ;48(9):2699-2699, Arthritis & rheumatism
— id: 55539, year: 2003, vol: 48, page: 2699, stat: Journal Article,

TGF beta: A fetal factor in the scarring cascade to anti-Ro associated congenital heart block (CHB)
Backer, C; Buyon, J; Clancy, R
2003 SEP ;48(9):S254-S254, Arthritis & rheumatism
— id: 55435, year: 2003, vol: 48, page: S254, stat: Journal Article,

From antibody insult to fibrosis in neonatal lupus - the heart of the matter
Buyon, Jill P; Clancy, Robert M
2003 ;5(6):266-270, Arthritis research & therapy
— id: 46212, year: 2003, vol: 5, page: 266, stat: Journal Article,

Maternal autoantibodies and congenital heart block: mediators, markers, and therapeutic approach
Buyon, Jill P; Clancy, Robert M
2003 May 2;33(3):140-154, Seminars in arthritis & rheumatism
— id: 46222, year: 2003, vol: 33, page: 140, stat: Journal Article,

Neonatal lupus syndromes
Buyon, Jill P; Clancy, Robert M
2003 Sep;15(5):535-541, Current opinion in rheumatology
— id: 39085, year: 2003, vol: 15, page: 535, stat: Journal Article,

Neonatal lupus: review of proposed pathogenesis and clinical data from the US-based Research Registry for Neonatal Lupus
Buyon, Jill P; Clancy, Robert M
2003 Feb;36(1):41-50, Autoimmunity
— id: 39218, year: 2003, vol: 36, page: 41, stat: Journal Article,

Congenital heart block: do fetal factors fuel the fire from inflammation to fibrosis?
Buyon, Jill P; Rupel, Ann; Clancy, Robert M
2003 ;12(10):731-734, Lupus
— id: 73534, year: 2003, vol: 12, page: 731, stat: Journal Article,

Fetal factors in neonatal lupus (NL): Association of a promoter polymorphism of tumor necrosis factor-alpha and HLA-DRB1 haplotype in children with rash
Clancy, R; Backer, C; Cohen, S; Yin, X; Buyon, J
2003 SEP ;48(9):S436-S436, Arthritis & rheumatism
— id: 55441, year: 2003, vol: 48, page: S436, stat: Journal Article,

Expression of endothelial cell protein C receptor and inducible nitric oxide synthase (iNOS) by circulating endothelial cells (CEC) in Systemic Lupus Erythematosus (SLE)
Clancy, R; Sesin, C; Kurosawa, S; Buyon, J
2003 SEP ;48(9):S374-S374, Arthritis & rheumatism
— id: 55439, year: 2003, vol: 48, page: S374, stat: Journal Article,

HLA-DRB1 relationships in neonatal lupus (NL) families
Clancy, R; Yin, X; Askanase, A; Miranda-Carus, E; Nelson, JL; Sestak, A; Harley, J; Buyon, J
2003 SEP ;48(9):S410-S411, Arthritis & rheumatism
— id: 55440, year: 2003, vol: 48, page: S410, stat: Journal Article,

Cytokine polymorphisms and histologic expression in autopsy studies: contribution of TNF-alpha and TGF-beta1 to the pathogenesis of autoimmune-associated congenital heart block
Clancy, Robert M; Backer, Chelsea B; Yin, Xiaoming; Kapur, Raj P; Molad, Yair; Buyon, Jill P
2003 Sep 15;171(6):3253-3261, Journal of immunology (1950)
— id: 39087, year: 2003, vol: 171, page: 3253, stat: Journal Article,

Clearance of apoptotic cells: TGF-beta in the balance between inflammation and fibrosis
Clancy, Robert M; Buyon, Jill P
2003 Dec;74(6):959-960, Journal of leukocyte biology
— id: 48186, year: 2003, vol: 74, page: 959, stat: Journal Article,

Does the cellular localization of antigens in or on apoptotic blebs influence the pathogenicity or benefit of cognate antibodies? Comment on the article by Dieude et al
Clancy, Robert M; Chan, Edward K L; Chandrashekhar, Sarayu; Buyon, Jill P
2003 Jul;48(7):2080-2; author reply 2082, Arthritis & rheumatism
— id: 73536, year: 2003, vol: 48, page: 2080, stat: Journal Article,

The resolution of inflammation: Prostaglandin E dissociates nuclear trafficking of individual NF-kB subunits (p65, p50) in stimulated rheumatoid synoviocytes
Gomez, PF; Pillinger, M; Clancy, R; Attur, M; Amin, A; Al-mussawir, H; Apsel, B; Bingham, CO; Abramson, SB
2003 SEP ;48(9):S253-S253, Arthritis & rheumatism
— id: 55434, year: 2003, vol: 48, page: S253, stat: Journal Article,

Formation of nitroxyl and hydroxyl radical in solutions of sodium trioxodinitrate: Effects of PH and cytotoxicity
Ivanova, J; Salama, G; Clancy, R; Schor, N; Stoyanovsky, D
2003 OCT ;35(11):S14-S15, Free radical biology & medicine
— id: 55391, year: 2003, vol: 35, page: S14, stat: Journal Article,

Formation of nitroxyl and hydroxyl radical in solutions of sodium trioxodinitrate: effects of pH and cytotoxicity
Ivanova, Juliana; Salama, Guy; Clancy, Robert M; Schor, Nina F; Nylander, Karen D; Stoyanovsky, Detcho A
2003 Oct 31;278(44):42761-42768, Journal of biological chemistry
— id: 134707, year: 2003, vol: 278, page: 42761, stat: Journal Article,

Electron-beam surface-patterned poly(ethylene glycol) microhydrogels
Krsko, P; Sukhishvili, S; Mansfield, M; Clancy, R; Libera, M
2003 JUL 8 ;19(14):5618-5625, Langmuir
— id: 37095, year: 2003, vol: 19, page: 5618, stat: Journal Article,

Differential effects of cyclooxygenase inhibitors on fibroblast-like synovial cells: Regulation of matrix metalloproteinase production via effects on Erk
Pillinger, MH; Dinsell, V; Tolani, SN; Apsel, B; Chang, LF; Gomez, P; Clancy, RM; Abramson, SB
2003 SEP ;48(9):S546-S547, Arthritis & rheumatism
— id: 55445, year: 2003, vol: 48, page: S546, stat: Journal Article,

Increased frequency of the high producer genotype TT (Codon 10) of TGF beta in congenital heart block and TNF2 allele in families with neonatal lupus
Backer, C; Loma-Sanner, I; Yin, X; Chandrashekhar, S; Sullivan, K; Clancy, R; Buyon, J
2002 SEP ;46(9):S621-S621, Arthritis & rheumatism
— id: 55555, year: 2002, vol: 46, page: S621, stat: Journal Article,

Role of NFkB and Rac in fibroblast activation: Key signaling molecules in the pathogenesis of congenital heart block (CAB)
Burg, N; Ross, C; Askanase, A; Buyon, J; Clancy, R
2002 SEP ;46(9):S254-S255, Arthritis & rheumatism
— id: 55553, year: 2002, vol: 46, page: S254, stat: Journal Article,

Cardiac 5-HT(4) Serotoninergic Receptors, 52kD SSA/Ro and Autoimmune-Associated Congenital Heart Block
Buyon, Jill P; Clancy, Robert; Di Donato, Francis; Miranda-Carus, M Eugenia; Askanase, Anca D; Garcia, Joanne; Qu, Yongxia; Hu, Keli; Yue, Yuankun; Chan, Edward K L; Boutjdir, Mohamed
2002 Aug;19(1-2):79-86, Journal of autoimmunity
— id: 32693, year: 2002, vol: 19, page: 79, stat: Journal Article,

Intracellular peroxynitrite formation promotes NFKB translocation and apoptosis in cytokine activated chondrocytes
Clancy, R; Gomez, P; Abramson, SB
2002 SEP ;46(9):S594-S594, Arthritis & rheumatism
— id: 55554, year: 2002, vol: 46, page: S594, stat: Journal Article,

Transdifferentiation of cardiac fibroblasts, a fetal factor in anti-SSA/Ro-SSB/La antibody-mediated congenital heart block
Clancy, Robert M; Askanase, Anca D; Kapur, Raj P; Chiopelas, Efstathia; Azar, Natalie; Miranda-Carus, M Eugenia; Buyon, Jill P
2002 Aug 15;169(4):2156-2163, Journal of immunology (1950)
— id: 32694, year: 2002, vol: 169, page: 2156, stat: Journal Article,

Circulating endothelial cells (CEC) in systemic lupus erythematosus: Activation markers and relationship to disease activity
Lee, E; Sesin, C; Abramson, S; Buyon, J; Clancy, R
2002 SEP ;46(9):S214-S214, Arthritis & rheumatism
— id: 55551, year: 2002, vol: 46, page: S214, stat: Journal Article,

The role of nitric oxide in tissue destruction
Abramson SB; Amin AR; Clancy RM; Attur M
2001 Dec;15(5):831-845, Bailliere's best practice & research. Clinical rheumatology
— id: 34868, year: 2001, vol: 15, page: 831, stat: Journal Article,

Nitric oxide and inflammatory mediators in the perpetuation of osteoarthritis
Abramson SB; Attur M; Amin AR; Clancy R
2001 Dec;3(6):535-541, Current rheumatology reports
— id: 26505, year: 2001, vol: 3, page: 535, stat: Journal Article,

Preparation and Properties of S-Nitroso-L-Cysteine Ethyl Ester, an Intracellular Nitrosating Agent
Clancy R; Cederbaum AI; Stoyanovsky DA
2001 Jun 7;44(12):2035-2038, Journal of medicinal chemistry
— id: 20636, year: 2001, vol: 44, page: 2035, stat: Journal Article,

Circulating activated endothelial cells in systemic lupus erythematosus: further evidence for diffuse vasculopathy
Clancy R; Marder G; Martin V; Belmont HM; Abramson SB; Buyon J
2001 May;44(5):1203-1208, Arthritis & rheumatism
— id: 20665, year: 2001, vol: 44, page: 1203, stat: Journal Article,

Activation of stress-activated protein kinase in osteoarthritic cartilage: evidence for nitric oxide dependence
Clancy R; Rediske J; Koehne C; Stoyanovsky D; Amin A; Attur M; Iyama K; Abramson SB
2001 May;9(4):294-299, Osteoarthritis & cartilage
— id: 20617, year: 2001, vol: 9, page: 294, stat: Journal Article,

Commentary
Clancy, R M
2001 Feb;7(1):15-15, Journal of clinical rheumatology. JCR
— id: 105917, year: 2001, vol: 7, page: 15, stat: Journal Article,

Functional genomic analysis in arthritis-affected cartilage: yin-yang regulation of inflammatory mediators by alpha 5 beta 1 and alpha V beta 3 integrins
Attur MG; Dave MN; Clancy RM; Patel IR; Abramson SB; Amin AR
2000 Mar 1;164(5):2684-2691, Journal of immunology (1950)
— id: 9724, year: 2000, vol: 164, page: 2684, stat: Journal Article,

Functional genomic analysis in arthritis-affected cartilage: Yin-yang regulation of inflammatory mediators by a5bl and avb3
Attur, MG; Dave, MN; Clancy, RM; Patel, IR; Abramson, SB; Amin, AR
2000 APR 20 ;14(6):A1152-A1152, FASEB journal
— id: 54645, year: 2000, vol: 14, page: A1152, stat: Journal Article,

Nitric oxide synthase/COX cross-talk: nitric oxide activates COX-1 but inhibits COX-2-derived prostaglandin production
Clancy R; Varenika B; Huang W; Ballou L; Attur M; Amin AR; Abramson SB
2000 Aug 1;165(3):1582-1587, Journal of immunology (1950)
— id: 48711, year: 2000, vol: 165, page: 1582, stat: Journal Article,

Circulating endothelial cells and vascular injury in systemic lupus erythematosus
Clancy RM
2000 Feb;2(1):39-43, Current rheumatology reports
— id: 39500, year: 2000, vol: 2, page: 39, stat: Journal Article,

Acetylcholine prevents intercellular adhesion molecule 1 (CD54)-induced focal adhesion complex assembly in endothelial cells via a nitric oxide-cGMP-dependent pathway
Clancy RM; Abramson SB
2000 Oct;43(10):2260-2264, Arthritis & rheumatism
— id: 39535, year: 2000, vol: 43, page: 2260, stat: Journal Article,

Anti-SSA/Ro and anti-SSB/La autoantibodies bind the surface of apoptotic fetal cardiocytes and promote secretion of TNF-alpha by macrophages
Miranda-Carus ME; Askanase AD; Clancy RM; Di Donato F; Chou TM; Libera MR; Chan EK; Buyon JP
2000 Nov 1;165(9):5345-5351, Journal of immunology (1950)
— id: 32697, year: 2000, vol: 165, page: 5345, stat: Journal Article,

In vitro and in vivo activation of polymorphonuclear leukocytes in response to particulate debris
Chen, F S; Scher, D M; Clancy, R M; Vera-Yu, A; Di Cesare, P E
1999 ;48(6):904-912, Journal of biomedical materials research
— id: 558512, year: 1999, vol: 48, page: 904, stat: Journal Article,

Nitric oxide alters chondrocyte function by disrupting cytoskeletal signaling complexes
Clancy R
1999 Jul;7(4):399-400, Osteoarthritis & cartilage
— id: 56461, year: 1999, vol: 7, page: 399, stat: Journal Article,

Effect of demineralized bone matrix on polymorphonuclear leukocyte degranulation
Kale AA; Clancy R; Leslie MP; Di Cesare PE
1999 Jul;17(4):598-606, Journal of orthopaedic research
— id: 6184, year: 1999, vol: 17, page: 598, stat: Journal Article,

Decomposition of sodium trioxodinitrate (Angeli's salt) to hydroxyl radical: An ESR spin-trapping study
Stoyanovsky, DA; Clancy, R; Cederbaum, AI
1999 JUN 2 ;121(21):5093-5094, Journal of the American Chemical Society
— id: 54037, year: 1999, vol: 121, page: 5093, stat: Journal Article,

The role of nitric oxide in inflammation and immunity
Clancy RM; Amin AR; Abramson SB
1998 Jul;41(7):1141-1151, Arthritis & rheumatism
— id: 9728, year: 1998, vol: 41, page: 1141, stat: Journal Article,

Activation of stress activated protein kinase in osteoarthritic cartilage: Evidence for nitric oxide dependence
Clancy, RM; Rediske, J; Nijher, N; Abramson, SB
1998 SEP ;41(9):S40-S40, Arthritis & rheumatism
— id: 53731, year: 1998, vol: 41, page: S40, stat: Journal Article,

IL-1 beta disrupts cross-talk between beta 3 and beta 1 integrins in osteoarthritic chondrocytes via the production of nitric oxide
Clancy, RM; Rediske, J; Nijher, N; Abramson, SB
1998 SEP ;41(9):S342-S342, Arthritis & rheumatism
— id: 53750, year: 1998, vol: 41, page: S342, stat: Journal Article,

Activation of endothelial cell cNOS prevents ICAM-1 induced focal adhesion complex assembly: A novel role for acetylcholine
Clancy, RM; Varenika, B; Nijher, N; Huang, W; Abramson, SB
1998 MAR ;46(3):196A-196A, Journal of investigative medicine
— id: 53493, year: 1998, vol: 46, page: 196A, stat: Journal Article,

The quantitation of nitric oxide dependent activation of stress activated protein kinase in osteoarthritic cartilage using a novel method of protein extraction
Clancy, RM; Veranika, B; Amin, A; Rediske, J; Abramson, SB
1998 MAR ;46(3):227A-227A, Journal of investigative medicine
— id: 53501, year: 1998, vol: 46, page: 227A, stat: Journal Article,

Nitric oxide attenuates cellular hexose monophosphate shunt response to oxidants in articular chondrocytes and acts to promote oxidant injury
Clancy RM; Abramson SB; Kohne C; Rediske J
1997 Aug;172(2):183-191, Journal of cellular physiology
— id: 7132, year: 1997, vol: 172, page: 183, stat: Journal Article,

Outside-in signaling in the chondrocyte. Nitric oxide disrupts fibronectin-induced assembly of a subplasmalemmal actin/rho A/focal adhesion kinase signaling complex
Clancy RM; Rediske J; Tang X; Nijher N; Frenkel S; Philips M; Abramson SB
1997 Oct 1;100(7):1789-1796, Journal of clinical investigation
— id: 9733, year: 1997, vol: 100, page: 1789, stat: Journal Article,

Activation of endothelial cell cNOS prevents ICAM-1 induced focal adhesion complex assembly: A novel role for acetylcholine
Clancy, R; Abramson, SB
1997 SEP ;40(9):594-594, Arthritis & rheumatism
— id: 53189, year: 1997, vol: 40, page: 594, stat: Journal Article,

Fibronectin and growth factors induce MAP kinase activation and promote proteoglycan synthesis in chondrocytes: Inhibition by nitric oxide via a cGMP dependent pathway
Clancy, R; Rediske, J; Pillinger, M; Abramson, SB
1997 SEP ;40(9):264-264, Arthritis & rheumatism
— id: 53180, year: 1997, vol: 40, page: 264, stat: Journal Article,

Exogenous nitric oxide or nitric oxide produced endogenously in response to FMLP inhibits neutrophil chemotaxis and augments degranulation via cyclic GMP kinase
Clancy, RM; Abramson, SB
1997 SEP ;40(9):595-595, Arthritis & rheumatism
— id: 53190, year: 1997, vol: 40, page: 595, stat: Journal Article,

Human neutrophils express mRNA for inducible nitric oxide synthase and exhibit intracellular nitric oxide-dependent autacoid functions upon activation, but lack detectable translated product and nitric oxide synthase enzyme activity
Amin, AR; Attur, M; Vyas, P; LeszczynskaPiziak, J; Levartovsky, D; Rediske, J; Clancy, RM; Vora, KA; Abramson, SB
1996 MAR ;44(3):A267-A267, Journal of investigative medicine
— id: 52957, year: 1996, vol: 44, page: A267, stat: Journal Article,

''Outside/in'' signalling in the chondrocyte: Effect of nitric oxide on fibronectin induced actin assembly and focal adhesion kinase-dependent tyrosine phosphorylation
Clancy, RM; Rediske, J; Tang, X; Frenkel, S; Abramson, SB
1996 MAR ;44(3):A241-A241, Journal of investigative medicine
— id: 52955, year: 1996, vol: 44, page: A241, stat: Journal Article,

alpha 5 beta 1 integrin signaling in the chondrocyte: Nitric oxide disrupts fibronectin induced assembly of a subplasmalemmal actin Rho A FAK activation complex
Clancy, RM; Rediske, J; Tang, XY; Frenkel, SR; Abramson, SB
1996 SEP ;39(9):843-843, Arthritis & rheumatism
— id: 52781, year: 1996, vol: 39, page: 843, stat: Journal Article,

Nitric oxide promotes the ADP-ribosylation of actin via the inhibition of cytosolic ADP-ribase(s)
Clancy, RM; Tang, X; Abramson, SB
1996 MAR ;44(3):A267-A267, Journal of investigative medicine
— id: 52958, year: 1996, vol: 44, page: A267, stat: Journal Article,

Nitric oxide promotes the ADP ribosylation of actin via the inhibition of cytosolic ADP ribase 1
Clancy, RM; Tang, XY; Abramson, SB
1996 SEP ;39(9):62-62, Arthritis & rheumatism
— id: 52776, year: 1996, vol: 39, page: 62, stat: Journal Article,

Effects of nitric oxide on chondrocyte migration, adhesion, and cytoskeletal assembly
Frenkel SR; Clancy RM; Ricci JL; Di Cesare PE; Rediske JJ; Abramson SB
1996 Nov;39(11):1905-1912, Arthritis & rheumatism
— id: 9737, year: 1996, vol: 39, page: 1905, stat: Journal Article,

Expression of nitric oxide synthase in human peripheral blood mononuclear cells and neutrophils
Amin AR; Attur M; Vyas P; Leszczynska-Piziak J; Levartovsky D; Rediske J; Clancy RM; Vora KA; Abramson SB
1995 96;47(4):190-205, Journal of inflammation
— id: 56922, year: 1995, vol: 47, page: 190, stat: Journal Article,

Nitric oxide stimulates ADP ribosylation of actin in association with the inhibition of actin polymerization in human neutrophils
Clancy R; Leszczynska J; Amin A; Levartovsky D; Abramson SB
1995 Aug;58(2):196-202, Journal of leukocyte biology
— id: 56748, year: 1995, vol: 58, page: 196, stat: Journal Article,

Nitric oxide: a novel mediator of inflammation
Clancy RM; Abramson SB
1995 Nov;210(2):93-101, Proceedings of the Society for Experimental Biology & Medicine
— id: 8336, year: 1995, vol: 210, page: 93, stat: Journal Article,

NITRIC-OXIDE INHIBITS CHONDROCYTE ADHESION TO FIBRONECTIN VIA EFFECTS ON INTRACELLULAR ACTIN POLYMERIZATION
CLANCY, RM; FRENKEL, SR; DICESARE, P; ABRAMSON, S
1995 SEP ;38(9):429-429, Arthritis & rheumatism
— id: 86694, year: 1995, vol: 38, page: 429, stat: Journal Article,

NITRIC-OXIDE MEDIATES CYTOKINE DEPENDENT OXIDANT INJURY IN CHONDROCYTES - EVIDENCE FOR ACTIVATION OF POLY(ADP-RIBOSE) SYNTHETASE
CLANCY, RM; REDISKE, J; KOEHNE, C; ABRAMSON, SB
1995 SEP ;38(9):239-239, Arthritis & rheumatism
— id: 86690, year: 1995, vol: 38, page: 239, stat: Journal Article,

Inhibition of neutrophil function by aspirin-like drugs (NSAIDS): requirement for assembly of heterotrimeric G proteins in bilayer phospholipid
Abramson SB; Leszczynska-Piziak J; Clancy RM; Philips M; Weissmann G
1994 Feb 9;47(3):563-572, Biochemical pharmacology
— id: 6306, year: 1994, vol: 47, page: 563, stat: Journal Article,

NITRIC-OXIDE INHIBITS CYTOSKELETAL ASSEMBLY IN ACTIVATED NEUTROPHILS VIA THE ADP-RIBOSYLATION OF ACTIN
ABRAMSON, SB; LESZCZYNSKAPIZIAK, J; CLANCY, RM
1994 APR ;42(2):A134-A134, Clinical research
— id: 52485, year: 1994, vol: 42, page: A134, stat: Journal Article,

Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediary
Clancy RM; Levartovsky D; Leszczynska-Piziak J; Yegudin J; Abramson SB
1994 Apr 26;91(9):3680-3684, Proceedings of the National Academy of Sciences of the United States of America
— id: 56508, year: 1994, vol: 91, page: 3680, stat: Journal Article,

ENDOTHELIAL-DERIVED RELAXATION FACTOR (NITRIC-OXIDE) AUGMENTS HUMAN NEUTROPHIL CHEMOTAXIS WHILE INHIBITING SUPEROXIDE ANION GENERATION
CLANCY, RM; ABRAMSON, SB
1994 APR ;42(2):A255-A255, Clinical research
— id: 52496, year: 1994, vol: 42, page: A255, stat: Journal Article,

NITRIC-OXIDE REACTS WITH INTRACELLULAR GLUTATHIONE AND ACTIVATES THE HEXOSE-MONOPHOSPHATE SHUNT IN HUMAN NEUTROPHILS - EVIDENCE FOR S-NITROSOGLUTATHIONE AS A BIOACTIVE INTERMEDIARY
CLANCY, RM; LEVARTOVSKY, D; LESZCZYNSKAPIZIAK, J; ABRAMSON, SB
1994 APR ;42(2):A113-A113, Clinical research
— id: 52481, year: 1994, vol: 42, page: A113, stat: Journal Article,

NITRIC-OXIDE PRODUCED BY HUMAN NEUTROPHILS ACTS AS A 2ND MESSENGER TO INHIBIT SUPEROXIDE ANION PRODUCTION AND ADP-RIBOSYLATE CYTOSOLIC PROTEINS
LEVARTOVSKY, D; CLANCY, RM; LESZCZYNSKAPIZIAK, J; ABRAMSON, SB
1994 APR ;42(2):A112-A112, Clinical research
— id: 52480, year: 1994, vol: 42, page: A112, stat: Journal Article,

The role of nitric oxide in the pathogenesis of preeclampsia
Seligman SP; Buyon JP; Clancy RM; Young BK; Abramson SB
1994 Oct;171(4):944-948, American journal of obstetrics & gynecology
— id: 6747, year: 1994, vol: 171, page: 944, stat: Journal Article,

Nitric oxide stimulates the ADP-ribosylation of actin in human neutrophils
Clancy RM; Leszczynska-Piziak J; Abramson SB
1993 Mar 31;191(3):847-852, Biochemical & biophysical research communications
— id: 6335, year: 1993, vol: 191, page: 847, stat: Journal Article,

NITRIC-OXIDE AND S-NITROSOGLUTATHIONE AUGMENT HUMAN NEUTROPHIL CHEMOTAXIS WHILE INHIBITING SUPEROXIDE ANION GENERATION - ROLE OF INTRACELLULAR S-NITROSOTHIOL FORMATION
CLANCY, R; YEGUDIN, J; LEVARTOVSKY, D; ABRAMSON, SB
1993 SEP ;36(9):S243-S243, Arthritis & rheumatism
— id: 52195, year: 1993, vol: 36, page: S243, stat: Journal Article,

NITRIC-OXIDE STIMULATES THE ADP-RIBOSYLATION OF ACTIN IN HUMAN NEUTROPHILS
CLANCY, RM; LESZCZYNSKAPIZIAK, J; ABRAMSON, SB
1993 APR ;41(2):A247-A247, Clinical research
— id: 54269, year: 1993, vol: 41, page: A247, stat: Journal Article,

EDRFS (NITRIC-OXIDE, S-NITROSOTHIOLS) AUGMENT HUMAN NEUTROPHIL CHEMOTAXIS WHILE INHIBITING SUPEROXIDE ANION GENERATION - ROLE OF INTRACELLULAR S-NITROSOTHIOL FORMATION
CLANCY, RM; LESZCZYNSKAPIZIAK, J; YEGUDIN, J; LEVARTOVSKY, D; ABRAMSON, SB
1993 APR ;41(2):A224-A224, Clinical research
— id: 54267, year: 1993, vol: 41, page: A224, stat: Journal Article,

Refractory postoperative torsades de pointes syndrome successfully treated with isoproterenol
Laub, G W; Muralidharan, S; Janeira, L; Moore, R A; Clancy, R; Adkins, M S; Fernandez, J; Anderson, W A; McGrath, L B
1993 Apr;7(2):210-212, Journal of cardiothoracic & vascular anesthesia
— id: 131410, year: 1993, vol: 7, page: 210, stat: Journal Article,

INTRACELLULAR NITRIC-OXIDE PRODUCED BY HUMAN NEUTROPHILS ACTS AS AN AUTACOID TO REGULATE SUPEROXIDE ANION PRODUCTION
LEVARTOVSKV, D; CLANCY, R; ABRAMSON, SB
1993 SEP ;36(9):S70-S70, Arthritis & rheumatism
— id: 52187, year: 1993, vol: 36, page: S70, stat: Journal Article,

Modulation of human T cell responses by nitric oxide and its derivative, S-nitrosoglutathione
Merryman PF; Clancy RM; He XY; Abramson SB
1993 Oct;36(10):1414-1422, Arthritis & rheumatism
— id: 9742, year: 1993, vol: 36, page: 1414, stat: Journal Article,

NITRIC-OXIDE DERIVATIVE, S-NITROSOGLUTATHIONE, BLOCKS IL-2 DEPENDENT DNA-SYNTHESIS VIA INHIBITION OF RIBONUCLEOTIDE REDUCTASE-ACTIVITY IN HUMAN T-CELLS
MERRYMAN, PF; CLANCY, RM; HAINES, KA; HE, Y; ABRAMSON, SB
1993 SEP ;36(9):S113-S113, Arthritis & rheumatism
— id: 52191, year: 1993, vol: 36, page: S113, stat: Journal Article,

TENIDAP POTENTIATES THE RESPONSE OF HUMAN T-LYMPHOCYTES TO NITRIC-OXIDE DERIVATIVE S-NITROSOGLUTATHIONE
MERRYMAN, PF; CLANCY, RM; HE, Y; ABRAMSON, SB
1993 APR ;41(2):A373-A373, Clinical research
— id: 54284, year: 1993, vol: 41, page: A373, stat: Journal Article,

EDRFS (NITRIC-OXIDE, S-NITROSOTHIOLS) AUGMENT HUMAN NEUTROPHIL CHEMOTAXIS WHILE INHIBITING SUPEROXIDE ANION GENERATION - ROLE OF INTRACELLULAR S-NITROSOTHIOL FORMATION
YEGUDIN, J; LEVARTOVSKY, D; CLANCY, RM; ABRAMSON, SB
1993 MAY ;36(5):R32-R32, Arthritis & rheumatism
— id: 54131, year: 1993, vol: 36, page: R32, stat: Journal Article,

NITRIC OXIDE-INDUCED ADP-RIBOSYLATION OF A 37KDA CYTOSOLIC PROTEIN IN HUMAN NEUTROPHILS PROMOTES ACTIN DEGRADATION
ABRAMSON, SB; LESZCZYNSKAPIZIAK, J; CLANCY, RM
1992 APR ;40(2):A248-A248, Clinical research
— id: 51987, year: 1992, vol: 40, page: A248, stat: Journal Article,

ASSEMBLY OF HETEROTRIMERIC G-PROTEINS IN A LIPID BILAYER IS REQUIRED FOR THE INHIBITION OF NEUTROPHIL FUNCTION BY NONSTEROIDAL ANTIINFLAMMATORY DRUGS
ABRAMSON, SB; LESZCZYNSKAPIZIAK, J; CLANCY, RM; PHILIPS, M; WEISSMANN, G
1992 APR ;40(2):A191-A191, Clinical research
— id: 51975, year: 1992, vol: 40, page: A191, stat: Journal Article,

Novel synthesis of S-nitrosoglutathione and degradation by human neutrophils
Clancy RM; Abramson SB
1992 Aug 1;204(2):365-371, Analytical biochemistry
— id: 9747, year: 1992, vol: 204, page: 365, stat: Journal Article,

Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase
Clancy RM; Leszczynska-Piziak J; Abramson SB
1992 Sep;90(3):1116-1121, Journal of clinical investigation
— id: 9746, year: 1992, vol: 90, page: 1116, stat: Journal Article,

NITRIC-OXIDE INHIBITS HUMAN NEUTROPHIL SUPEROXIDE ANION PRODUCTION VIA DIRECT ACTION ON A MEMBRANE COMPONENT OF THE NADPH-OXIDASE
CLANCY, R; LESZCZYNSKAPIZIAK, J; ABRAMSON, S
1992 SEP ;35(9):S96-S96, Arthritis & rheumatism
— id: 51846, year: 1992, vol: 35, page: S96, stat: Journal Article,

ACTIVATED HUMAN NEUTROPHILS DEGRADE S-NITROSOCYSTEINE, AN ENDOTHELIAL DERIVED RELAXATION FACTOR
CLANCY, RM; ABRAMSON, SB
1992 APR ;40(2):A323-A323, Clinical research
— id: 52001, year: 1992, vol: 40, page: A323, stat: Journal Article,

NITRIC-OXIDE INHIBITS HUMAN NEUTROPHIL SUPEROXIDE ANION PRODUCTION VIA DIRECT ACTION ON THE NADPH-OXIDASE
CLANCY, RM; LESZCZYNSKAPIZIAK, J; MUSCAT, S; ABRAMSON, SB
1992 APR ;40(2):A248-A248, Clinical research
— id: 51988, year: 1992, vol: 40, page: A248, stat: Journal Article,

Cryopreserved allograft veins as alternative coronary artery bypass conduits: early phase results
Laub, G W; Muralidharan, S; Clancy, R; Eldredge, W J; Chen, C; Adkins, M S; Fernandez, J; Anderson, W A; McGrath, L B
1992 Nov;54(5):826-831, Annals of thoracic surgery
— id: 131412, year: 1992, vol: 54, page: 826, stat: Journal Article,

NITRIC-OXIDE DERIVATIVE S-NITROSOGLUTATHIONE INHIBITS T-CELL PROLIFERATION AND INDUCES ACCUMULATION OF CYCLIC GUANOSINE 3,5'-MONOPHOSPHATE
MERRYMAN, PF; CLANCY, RM; HE, X; ABRAMSON, SB
1992 APR ;40(2):A262-A262, Clinical research
— id: 51993, year: 1992, vol: 40, page: A262, stat: Journal Article,

ENDOTHELIAL DEFENSES AGAINST ATTACK BY HUMAN NEUTROPHILS - NITRIC-OXIDE INHIBITS NEUTROPHIL FUNCTION
CLANCY, RM; ABRAMSON, SB
1991 APR ;39(2):A225-A225, Clinical research
— id: 51607, year: 1991, vol: 39, page: A225, stat: Journal Article,

Focal motor seizures heralding stroke in full-term neonates
Clancy, R; Malin, S; Laraque, D; Baumgart, S; Younkin, D
1985 Jun;139(6):601-606, American journal of diseases of children
— id: 849132, year: 1985, vol: 139, page: 601, stat: Journal Article,