Barry Reisberg

Biosketch / Results /

Barry Reisberg

Professor, Department of Psychiatry
Clinical Dir Aging & Dementia Rsch Ctr, Director of the Zachary and Elizabeth M. Fisher Alzheimer Disease Education and Research program

Contact Info

145 East 32nd Street
New York, NY 10016



1973-1975 — Metropolitan Hospital (Psychiatry & Neurology), Residency Training

Research Summary

Barry Reisberg, M.D. has directed research over the past three decades which has significantly advanced current understanding and treatment of Alzheimer's disease (AD). He was the first to describe many of the most important symptoms of AD and the characteristic clinical course of the disease. His staging tools are presently governmentally mandated measures throughout the U.S., in some Canadian and European provinces, and recommended in Japan. Dr. Reisberg's work has been instrumental in the worldwide development of all three major current pharmacological treatment modalities for AD, i.e., glutamatergic antagonist treatment (memantine), treatment for behavioral disturbances in dementia (e.g., risperidone), and in the development and approval of cholinesterase inhibitor treatment (e.g., rivastigmine for mild to moderate dementia and donepezil for severe dementia). For example, Dr. Reisberg was the principal designer and Principal Investigator of the pivotal trial, published in the New England Journal of Medicine, which resulted in the US and European Union approval of the first treatment for advanced AD, memantine. Dr. Reisberg and his associates developed the concepts behind and coined the terminology, "mild cognitive impairment," a now universally recognized entity. His descriptions of an even earlier clinically manifest stage - "subjective cognitive impairment," are increasingly being recognized as the earliest manifestations of AD in seemingly normal persons. At the other end of the severity spectrum, Dr. Reisberg's staging procedures have been used in the pivotal worldwide trials of all currently approved medications for advanced AD. Dr. Reisberg's description of the retrogenic neurodevelopmental process in AD and related dementias is also advancing a new science of AD management and providing new insights into AD etiopathogenesis. Dr. Reisberg has been the recipient of numerous grants and awards for his pioneering research including a Lifetime Achievement Award for Research in Alzheimer's disease from the major worldwide organizations in the field. Dr. Reisberg is the Director of the Clinical Core of the US National Institute on Aging (NIH) funded Alzheimer's Disease Center of the New York University School of Medicine and Clinical Director of the Aging and Dementia Research Center of the NYU School of Medicine. He serves as Professor of Psychiatry at NYU. Dr. Reisberg is also Director of the Zachary and Elizabeth M. Fisher Alzheimer's Disease Education and Resources Program at the NYU School of Medicine. Additionally, Dr. Reisberg is an Adjunct Professor at the McGill University Faculty of Medicine in Montreal, Canada.

Research Interests

Treatment, Management, and Prevention of Alzheimer's Disease

Evidence for affective symptoms as an early manifestation of cognitive change
Guillo-Benarous, F; Sidhu, J; Patel, P; Naqvi, S; Thu, M; Ghimire, S; Xu, J; Reisberg, B
2015-05-04; 1660-2854,Neuro-degenerative diseases - id: 1560382, year: 2015

Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures used Across 19 International Research Studies
Rabin, Laura A; Smart, Colette M; Crane, Paul K; Amariglio, Rebecca E; Berman, Lorin M; Boada, Merce; Buckley, Rachel F; Chetelat, Gael; Dubois, Bruno; Ellis, Kathryn A; Gifford, Katherine A; Jefferson, Angela L; Jessen, Frank; Katz, Mindy J; Lipton, Richard B; Luck, Tobias; Maruff, Paul; Mielke, Michelle M; Molinuevo, Jose Luis; Naeem, Farnia; Perrotin, Audrey; Petersen, Ronald C; Rami, Lorena; Reisberg, Barry; Rentz, Dorene M; Riedel-Heller, Steffi G; Risacher, Shannon L; Rodriguez, Octavio; Sachdev, Perminder S; Saykin, Andrew J; Slavin, Melissa J; Snitz, Beth E; Sperling, Reisa A; Tandetnik, Caroline; van der Flier, Wiesje M; Wagner, Michael; Wolfsgruber, Steffen; Sikkes, Sietske A M
2015-09-27; 1875-8908,Journal of Alzheimer's disease - id: 1786922, year: 2015 JOURNAL ARTICLE

2014 Report on the Milestones for the US National Plan to Address Alzheimer's Disease
Fargo, Keith N; Aisen, Paul; Albert, Marilyn; Au, Rhoda; Corrada, Maria M; DeKosky, Steven; Drachman, David; Fillit, Howard; Gitlin, Laura; Haas, Magali; Herrup, Karl; Kawas, Claudia; Khachaturian, Ara S; Khachaturian, Zaven S; Klunk, William; Knopman, David; Kukull, Walter A; Lamb, Bruce; Logsdon, Rebecca G; Maruff, Paul; Mesulam, Marsel; Mobley, William; Mohs, Richard; Morgan, David; Nixon, Ralph A; Paul, Steven; Petersen, Ronald; Plassman, Brenda; Potter, William; Reiman, Eric; Reisberg, Barry; Sano, Mary; Schindler, Rachel; Schneider, Lon S; Snyder, Peter J; Sperling, Reisa A; Yaffe, Kristine; Bain, Lisa J; Thies, William H; Carrillo, Maria C
2014-10-27; 1552-5260,Alzheimer's & dementia - id: 1316462, year: 2014 JOURNAL ARTICLE

Neuropsychological and Neuropsychiatric Prediction of Global Cognitive Status Among Older Spanish-Speaking Hispanics and English-Speaking Whites
Guerrero-Berroa, Elizabeth; Kluger, Alan; Schmeidler, James; Sailor, Kevin; Lizardi, Humberto; Golomb, James; Ferris, Steven; Reisberg, Barry
2014-05-04; 0891-9887,Journal of geriatric psychiatry & neurology - id: 948142, year: 2014 JOURNAL ARTICLE

A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease
Jessen, Frank; Amariglio, Rebecca E; van Boxtel, Martin; Breteler, Monique; Ceccaldi, Mathieu; Chetelat, Gael; Dubois, Bruno; Dufouil, Carole; Ellis, Kathryn A; van der Flier, Wiesje M; Glodzik, Lidia; van Harten, Argonde C; de Leon, Mony J; McHugh, Pauline; Mielke, Michelle M; Molinuevo, Jose Luis; Mosconi, Lisa; Osorio, Ricardo S; Perrotin, Audrey; Petersen, Ronald C; Rabin, Laura A; Rami, Lorena; Reisberg, Barry; Rentz, Dorene M; Sachdev, Perminder S; de la Sayette, Vincent; Saykin, Andrew J; Scheltens, Philip; Shulman, Melanie B; Slavin, Melissa J; Sperling, Reisa A; Stewart, Robert; Uspenskaya, Olga; Vellas, Bruno; Visser, Pieter Jelle; Wagner, Michael
2014-05-07; 1552-5260,Alzheimer's & dementia - id: 956732, year: 2014 JOURNAL ARTICLE