Ravichandran Ramasamy

Biosketch / Results /

Ravichandran Ramasamy, D.Phil.

Associate Professor;
Departments of Medicine (Endoc-Diab Rsch Pgm) and Biochemistry and Molecular Pharmacology

Contact Info

Address

Floor 9 Room 904
Smilow Research Building
,

212-263-9475
Ravichandran.Ramasamy@nyumc.org

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All data from NYU Health Sciences Library Faculty Bibliography — -

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http://hsl.med.nyu.edu/faculty-bibliography-search

RAGE Regulates the Metabolic and Inflammatory Response to High Fat Feeding in Mice
Song, Fei; Hurtado Del Pozo, Carmen; Rosario, Rosa; Zou, Yu Shan; Ananthakrishnan, Radha; Xu, Xiaoyuan; Patel, Payal R; Benoit, Vivian M; Yan, Shi Fang; Li, Huilin; Friedman, Richard A; Kim, Jason K; Ramasamy, Ravichandran; Ferrante, Anthony W Jr; Schmidt, Ann Marie
2014 Feb;:1948-1965, Diabetes
— id: 972332, year: 2014, vol: , page: 1948, stat: Journal Article,

Aldose reductase drives hyperacetylation of egr-1 in hyperglycemia and consequent upregulation of proinflammatory and prothrombotic signals
Vedantham, Srinivasan; Thiagarajan, Devi; Ananthakrishnan, Radha; Wang, Lingjie; Rosario, Rosa; Zou, Yu Shan; Goldberg, Ira; Yan, Shi Fang; Schmidt, Ann Marie; Ramasamy, Ravichandran
2014 Feb;63(2):761-774, Diabetes
— id: 777962, year: 2014, vol: 63, page: 761, stat: Journal Article,

Carbon monoxide form of PEGylated hemoglobin protects myocardium against ischemia/reperfusion injury in diabetic and normal mice
Ananthakrishnan, Radha; Li, Qing; O'Shea, Karen M; Quadri, Nosirudeen; Wang, Lingjie; Abuchowski, Abraham; Schmidt, Ann Marie; Ramasamy, Ravichandran
2013 Dec;41(6):428-436, Artificial cells, nanomedicine, & biotechnology
— id: 665972, year: 2013, vol: 41, page: 428, stat: Journal Article,

Alterations in ventricular K(ATP) channel properties during aging
Bao, Li; Taskin, Eylem; Foster, Monique; Ray, Beevash; Rosario, Rosa; Ananthakrishnan, Radha; Howlett, Susan E; Schmidt, Ann M; Ramasamy, Ravichandran; Coetzee, William A
2013 Feb;12(1):167-176, Aging cell
— id: 213602, year: 2013, vol: 12, page: 167, stat: Journal Article,

Radical Roles for RAGE in the Pathogenesis of Oxidative Stress in Cardiovascular Diseases and Beyond
Daffu, Gurdip; Del Pozo, Carmen Hurtado; O'Shea, Karen M; Ananthakrishnan, Radha; Ramasamy, Ravichandran; Schmidt, Ann Marie
2013 ;14(10):19891-19910, International journal of molecular sciences
— id: 574032, year: 2013, vol: 14, page: 19891, stat: Journal Article,

Unlocking the biology of RAGE in diabetic microvascular complications
Manigrasso, Michaele B; Juranek, Judyta; Ramasamy, Ravichandran; Schmidt, Ann Marie
2013 Sep;:15-22, Trends in endocrinology & metabolism
— id: 528182, year: 2013, vol: , page: 15, stat: Journal Article,

Aldose reductase & RAGE: Novel therapeutic adjuncts for cardioprotection
Ramasamy, R.
2013 ;126 2 2:232-232, Cardiology
— id: 657922, year: 2013, vol: 126 2 2, page: 232, stat: Journal Article,

Acute administration of N-3 triglyceride emulsion provides marked cardioprotection after ischemia/reperfusion
Zirpoli, H; Abdillahi, M; Quadri, N; Ananthakrishnan, R; Zhu, Z; Wang, L; Li, Q; Deckelbaum, R J; Ramasamy, R
2013 April 2013;27:-, FASEB journal
— id: 550812, year: 2013, vol: 27, page: , stat: Journal Article,

Aldose reductase modulates cardiac glycogen synthase kinase-3beta phosphorylation during ischemia-reperfusion
Abdillahi, Mariane; Ananthakrishnan, Radha; Vedantham, Srinivasan; Shang, Linshan; Zhu, Zhengbin; Rosario, Rosa; Zirpoli, Hylde; Bohren, Kurt M; Gabbay, Kenneth H; Ramasamy, Ravichandran
2012 Aug;303(3):H297-H308, American journal of physiology. Heart & circulatory physiology
— id: 174379, year: 2012, vol: 303, page: H297, stat: Journal Article,

Insulin resistance: metabolic mechanisms and consequences in the heart
Abel, E Dale; O'Shea, Karen M; Ramasamy, Ravichandran
2012 Sep;32(9):2068-2076, Arteriosclerosis, thrombosis, & vascular biology
— id: 174414, year: 2012, vol: 32, page: 2068, stat: Journal Article,

Lysophosphatidic acid targets vascular and oncogenic pathways via RAGE signaling
Rai, Vivek; Toure, Fatouma; Chitayat, Seth; Pei, Renjun; Song, Fei; Li, Qing; Zhang, Jinghua; Rosario, Rosa; Ramasamy, Ravichandran; Chazin, Walter J; Schmidt, Ann Marie
2012 Dec;209(13):2339-2350, Journal of experimental medicine
— id: 203922, year: 2012, vol: 209, page: 2339, stat: Journal Article,

Advanced glycation endproducts: from precursors to RAGE: round and round we go
Ramasamy R; Yan SF; Schmidt AM
2012 Apr;42(4):1151-1161, Amino acids
— id: 138340, year: 2012, vol: 42, page: 1151, stat: Journal Article,

Receptor for Advanced Glycation End Products (RAGE) and Implications for the Pathophysiology of Heart Failure
Ramasamy, Ravichandran; Schmidt, Ann Marie
2012 Jun;9(2):107-116, Current heart failure reports
— id: 166791, year: 2012, vol: 9, page: 107, stat: Journal Article,

The diverse ligand repertoire of the receptor for advanced glycation endproducts and pathways to the complications of diabetes
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2012 Nov;57(5-6):160-167, Vascular pharmacology
— id: 178279, year: 2012, vol: 57, page: 160, stat: Journal Article,

Cardiomyocyte aldose reductase causes heart failure and impairs recovery from ischemia
Son, Ni-Huiping; Ananthakrishnan, Radha; Yu, Shuiqing; Khan, Raffay S; Jiang, Hongfeng; Ji, Ruiping; Akashi, Hirokazu; Li, Qing; O'Shea, Karen; Homma, Shunichi; Goldberg, Ira J; Ramasamy, Ravichandran
2012 ;7(9):e46549-e46549 e46549, PLoS one
— id: 185262, year: 2012, vol: 7, page: e46549, stat: Journal Article,

Quantifying course of RAGE expression after myocardial reperfusion injury
Tekabe, Y; Luma, J; Li, Q; Ramasamy, R; Schmidt, A M; Johnson, L
2012 February 2012;14:S825-S825, Molecular imaging & biology
— id: 171163, year: 2012, vol: 14, page: S825, stat: Journal Article,

Imaging of receptors for advanced glycation end products in experimental myocardial ischemia and reperfusion injury
Tekabe, Yared; Luma, Joane; Li, Qing; Schmidt, Ann Marie; Ramasamy, Ravichandran; Johnson, Lynne L
2012 Jan;5(1):59-67, JACC: Cardiovascular imaging
— id: 155936, year: 2012, vol: 5, page: 59, stat: Journal Article,

Formin mDia1 Mediates Vascular Remodeling via Integration of Oxidative and Signal Transduction Pathways
Toure, Fatouma; Fritz, Gunter; Li, Qing; Rai, Vivek; Daffu, Gurdip; Zou, Yu Shan; Rosario, Rosa; Ramasamy, Ravichandran; Alberts, Arthur S; Yan, Shi Fang; Schmidt, Ann Marie
2012 May;110(10):1279-1293, Circulation research
— id: 166826, year: 2012, vol: 110, page: 1279, stat: Journal Article,

Aldose reductase, oxidative stress and diabetic cardiovascular complications
Vedantham, Srinivasan; Ananthakrishnan, Radha; Schmidt, Ann Marie; Ramasamy, Ravichandran
2012 Sep;10(3):234-240, Cardiovascular & hematological agents in medicinal chemistry
— id: 174070, year: 2012, vol: 10, page: 234, stat: Journal Article,

Opposing roles of RAGE and Myd88 signaling in extensive liver resection
Zeng S; Zhang QY; Huang J; Vedantham S; Rosario R; Ananthakrishnan R; Yan SF; Ramasamy R; Dematteo RP; Emond JC; Friedman RA; Schmidt AM
2012 Feb;26(2):882-893, FASEB journal
— id: 141686, year: 2012, vol: 26, page: 882, stat: Journal Article,

Aldose reductase pathway contributes to vulnerability of aging myocardium to ischemic injury
Ananthakrishnan, Radha; Li, Qing; Gomes, Teodoro; Schmidt, Ann Marie; Ramasamy, Ravichandran
2011 Sep;46(9):762-767, Experimental gerontology
— id: 137436, year: 2011, vol: 46, page: 762, stat: Journal Article,

Receptor for AGE (RAGE): signaling mechanisms in the pathogenesis of diabetes and its complications
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2011 Dec;1243(1):88-102, Annals of the New York Academy of Sciences
— id: 148734, year: 2011, vol: 1243, page: 88, stat: Journal Article,

Human aldose reductase expression accelerates atherosclerosis in diabetic apolipoprotein e-/- mice
Vedantham, Srinivasan; Noh, Hyelim; Ananthakrishnan, Radha; Son, Ni; Hallam, Kellie; Hu, Yunying; Yu, Shuiquing; Shen, Xiaoping; Rosario, Rosa; Lu, Yan; Ravindranath, Thyyar; Drosatos, Konstantinos; Huggins, Lesley Ann; Schmidt, Ann Marie; Goldberg, Ira J; Ramasamy, Ravichandran
2011 Aug;31(8):1805-1813, Arteriosclerosis, thrombosis, & vascular biology
— id: 135542, year: 2011, vol: 31, page: 1805, stat: Journal Article,

RAGE, glomerulosclerosis and proteinuria: roles in podocytes and endothelial cells
D'Agati, Vivette; Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2010 Jan;21(1):50-56, Trends in endocrinology & metabolism
— id: 130808, year: 2010, vol: 21, page: 50, stat: Journal Article,

Aldose reductase and AGE-RAGE pathways: central roles in the pathogenesis of vascular dysfunction in aging rats
Hallam, Kellie McCormick; Li, Qing; Ananthakrishnan, Radha; Kalea, Anastasia; Zou, Yu S; Vedantham, Srinivasan; Schmidt, Ann Marie; Yan, Shi Fang; Ramasamy, Ravichandran
2010 Oct;9(5):776-784, Aging cell
— id: 130803, year: 2010, vol: 9, page: 776, stat: Journal Article,

Morphological Changes and Immunohistochemical Expression of RAGE and its Ligands in the Sciatic Nerve of Hyperglycemic Pig (Sus Scrofa)
Juranek, Judyta K; Aleshin, Alexey; Rattigan, Eileen M; Johnson, Lynne; Qu, Wu; Song, Fei; Ananthakrishnan, Radha; Quadri, Nosirudeen; Yan, Shi Du; Ramasamy, Ravichandran; Schmidt, Ann Marie; Geddis, Matthew S
2010 Sep;2010(3):47-59, Biochemistry insights
— id: 528222, year: 2010, vol: 2010, page: 47, stat: Journal Article,

Aldose reductase and cardiovascular diseases, creating human-like diabetic complications in an experimental model
Ramasamy, Ravichandran; Goldberg, Ira J
2010 May 14;106(9):1449-1458, Circulation research
— id: 130835, year: 2010, vol: 106, page: 1449, stat: Journal Article,

Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse
Reiniger, Nina; Lau, Kai; McCalla, Daren; Eby, Bonnie; Cheng, Bin; Lu, Yan; Qu, Wu; Quadri, Nosirudeen; Ananthakrishnan, Radha; Furmansky, Maryana; Rosario, Rosa; Song, Fei; Rai, Vivek; Weinberg, Alan; Friedman, Richard; Ramasamy, Ravichandran; D'Agati, Vivette; Schmidt, Ann Marie
2010 Aug;59(8):2043-2054, Diabetes
— id: 130804, year: 2010, vol: 59, page: 2043, stat: Journal Article,

RAGE modulates hypoxia/reoxygenation injury in adult murine cardiomyocytes via JNK and GSK-3beta signaling pathways
Shang, Linshan; Ananthakrishnan, Radha; Li, Qing; Quadri, Nosirudeen; Abdillahi, Mariane; Zhu, Zhengbin; Qu, Wu; Rosario, Rosa; Toure, Fatouma; Yan, Shi Fang; Schmidt, Ann Marie; Ramasamy, Ravichandran
2010 ;5(4):e10092-e10092, PLoS one
— id: 130806, year: 2010, vol: 5, page: e10092, stat: Journal Article,

Soluble RAGE: therapy and biomarker in unraveling the RAGE axis in chronic disease and aging
Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2010 May 15;79(10):1379-1386, Biochemical pharmacology
— id: 130805, year: 2010, vol: 79, page: 1379, stat: Journal Article,

The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature
Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2010 Mar 19;106(5):842-853, Circulation research
— id: 130807, year: 2010, vol: 106, page: 842, stat: Journal Article,

Aldose reductase mediates myocardial ischemia-reperfusion injury in part by opening mitochondrial permeability transition pore
Ananthakrishnan, Radha; Kaneko, Michiyo; Hwang, Yuying C; Quadri, Nosirudeen; Gomez, Teodoro; Li, Qing; Caspersen, Casper; Ramasamy, Ravichandran
2009 Feb;296(2):H333-H341, American journal of physiology. Heart & circulatory physiology
— id: 130839, year: 2009, vol: 296, page: H333, stat: Journal Article,

Inflammatory stress in primary venous and aortic endothelial cells of type 1 diabetic mice
Bucciarelli, Loredana G; Pollreisz, Andreas; Kebschull, Moritz; Ganda, Anjali; Kalea, Anastasia Z; Hudson, Barry I; Zou, Yu Shan; Lalla, Evanthia; Ramasamy, Ravichandran; Colombo, Paolo C; Schmidt, Ann Marie; Yan, Shi Fang
2009 Oct;6(4):249-261, Diabetes & vascular disease research
— id: 130799, year: 2009, vol: 6, page: 249, stat: Journal Article,

RAGE: therapeutic target and biomarker of the inflammatory response--the evidence mounts
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2009 Sep;86(3):505-512, Journal of leukocyte biology
— id: 130810, year: 2009, vol: 86, page: 505, stat: Journal Article,

Novel role for aldose reductase in mediating acute inflammatory responses in the lung
Ravindranath, Thyyar M; Mong, Phyllus Y; Ananthakrishnan, Radha; Li, Qing; Quadri, Nosirudeen; Schmidt, Ann Marie; Ramasamy, Ravichandran; Wang, Qin
2009 Dec 15;183(12):8128-8137, Journal of immunology
— id: 130809, year: 2009, vol: 183, page: 8128, stat: Journal Article,

Receptor for AGE (RAGE) and its ligands-cast into leading roles in diabetes and the inflammatory response
Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2009 Mar;87(3):235-247, Journal of molecular medicine (Berlin)
— id: 130812, year: 2009, vol: 87, page: 235, stat: Journal Article,

The receptor for advanced glycation endproducts (RAGE) and cardiovascular disease
Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2009 ;11:e9-e9, Expert reviews in molecular medicine
— id: 130811, year: 2009, vol: 11, page: e9, stat: Journal Article,

Tempering the wrath of RAGE: an emerging therapeutic strategy against diabetic complications, neurodegeneration, and inflammation
Yan, Shi Fang; Yan, Shi Du; Ramasamy, Ravichandran; Schmidt, Ann Marie
2009 ;41(6):408-422, Annals of medicine (Helsinki)
— id: 130813, year: 2009, vol: 41, page: 408, stat: Journal Article,

RAGE modulates myocardial injury consequent to LAD infarction via impact on JNK and STAT signaling in a murine model
Aleshin, Alexey; Ananthakrishnan, Radha; Li, Qing; Rosario, Rosa; Lu, Yan; Qu, Wu; Song, Fei; Bakr, Soliman; Szabolcs, Matthias; D'Agati, Vivette; Liu, Rui; Homma, Shunichi; Schmidt, Ann Marie; Yan, Shi Fang; Ramasamy, Ravichandran
2008 Apr;294(4):H1823-H1832, American journal of physiology. Heart & circulatory physiology
— id: 130818, year: 2008, vol: 294, page: H1823, stat: Journal Article,

RAGE and modulation of ischemic injury in the diabetic myocardium
Bucciarelli, Loredana G; Ananthakrishnan, Radha; Hwang, Yuying C; Kaneko, Michiyo; Song, Fei; Sell, David R; Strauch, Christopher; Monnier, Vincent M; Yan, Shi Fang; Schmidt, Ann Marie; Ramasamy, Ravichandran
2008 Jul;57(7):1941-1951, Diabetes
— id: 130800, year: 2008, vol: 57, page: 1941, stat: Journal Article,

RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis
Guo, Jiancheng; Ananthakrishnan, Radha; Qu, Wu; Lu, Yan; Reiniger, Nina; Zeng, Shan; Ma, Wanchao; Rosario, Rosa; Yan, Shi Fang; Ramasamy, Ravichandran; D'Agati, Vivette; Schmidt, Ann Marie
2008 May;19(5):961-972, Journal of the American Society of Nephrology
— id: 130816, year: 2008, vol: 19, page: 961, stat: Journal Article,

Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice
Harja, Evis; Bu, De-xiu; Hudson, Barry I; Chang, Jong Sun; Shen, Xiaoping; Hallam, Kellie; Kalea, Anastasia Z; Lu, Yan; Rosario, Rosa H; Oruganti, Sai; Nikolla, Zana; Belov, Dmitri; Lalla, Evanthia; Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2008 Jan;118(1):183-194, Journal of clinical investigation
— id: 130821, year: 2008, vol: 118, page: 183, stat: Journal Article,

PKCbeta modulates ischemia-reperfusion injury in the heart
Kong, Linghua; Andrassy, Martin; Chang, Jong Sun; Huang, Chun; Asai, Tomohiro; Szabolcs, Matthias J; Homma, Shunichi; Liu, Rui; Zou, Yu Shan; Leitges, Michael; Yan, Shi Du; Ramasamy, Ravichandran; Schmidt, Ann Marie; Yan, Shi-Fang
2008 Apr;294(4):H1862-H1870, American journal of physiology. Heart & circulatory physiology
— id: 130819, year: 2008, vol: 294, page: H1862, stat: Journal Article,

Polyol pathway and modulation of ischemia-reperfusion injury in Type 2 diabetic BBZ rat hearts
Li, Qing; Hwang, Yuying C; Ananthakrishnan, Radha; Oates, Peter J; Guberski, Dennis; Ramasamy, Ravichandran
2008 ;7:33-33, Cardiovascular diabetology
— id: 130791, year: 2008, vol: 7, page: 33, stat: Journal Article,

Receptor for advanced glycation end products: fundamental roles in the inflammatory response: winding the way to the pathogenesis of endothelial dysfunction and atherosclerosis
Ramasamy, Ravichandran; Yan, Shi Fang; Herold, Kevan; Clynes, Raphael; Schmidt, Ann Marie
2008 Apr;1126:7-13, Annals of the New York Academy of Sciences
— id: 130820, year: 2008, vol: 1126, page: 7, stat: Journal Article,

Stopping the primal RAGE reaction in myocardial infarction: capturing adaptive responses to heal the heart?
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2008 Jun 24;117(25):3165-3167, Circulation
— id: 130815, year: 2008, vol: 117, page: 3165, stat: Journal Article,

Blockade of receptor for advanced glycation end product attenuates pulmonary reperfusion injury in mice
Sternberg, David I; Gowda, Ram; Mehra, Divya; Qu, Wu; Weinberg, Alan; Twaddell, William; Sarkar, Joydeep; Wallace, Allison; Hudson, Barry; D'Ovidio, Frank; Arcasoy, Selim; Ramasamy, Ravichandran; D'Armiento, Jeanine; Schmidt, Ann Marie; Sonett, Joshua R
2008 Dec;136(6):1576-1585, Journal of thoracic & cardiovascular surgery
— id: 130814, year: 2008, vol: 136, page: 1576, stat: Journal Article,

Mechanisms of disease: advanced glycation end-products and their receptor in inflammation and diabetes complications
Yan, Shi Fang; Ramasamy, Ravichandran; Schmidt, Ann Marie
2008 May;4(5):285-293, Nature clinical practice. Endocrinology & metabolism
— id: 130817, year: 2008, vol: 4, page: 285, stat: Journal Article,

Receptor for AGE (RAGE): weaving tangled webs within the inflammatory response
Clynes, Raphael; Moser, Bernhard; Yan, Shi Fang; Ramasamy, Ravichandran; Herold, Kevan; Schmidt, Ann Marie
2007 Dec;7(8):743-751, Current molecular medicine
— id: 130822, year: 2007, vol: 7, page: 743, stat: Journal Article,

Receptor for advanced glycation end products (RAGE) in a dash to the rescue: inflammatory signals gone awry in the primal response to stress
Herold, Kevan; Moser, Bernhard; Chen, Yali; Zeng, Shan; Yan, Shi Fang; Ramasamy, Ravichandran; Emond, Jean; Clynes, Raphael; Schmidt, Ann Marie
2007 Aug;82(2):204-212, Journal of leukocyte biology
— id: 130825, year: 2007, vol: 82, page: 204, stat: Journal Article,

Arguing for the motion: yes, RAGE is a receptor for advanced glycation endproducts
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2007 Sep;51(9):1111-1115, Molecular nutrition & food research
— id: 130824, year: 2007, vol: 51, page: 1111, stat: Journal Article,

The biology of RAGE and its ligands: uncovering mechanisms at the heart of diabetes and its complications
Yan, Shi Fang; Barile, Gaetano R; D'Agati, Vivette; Du Yan, Shi; Ramasamy, Ravichandran; Schmidt, Ann Marie
2007 Apr;7(2):146-153, Current diabetes reports
— id: 130826, year: 2007, vol: 7, page: 146, stat: Journal Article,

Receptor for Advanced Glycation Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes & aging
Yan, Shi Fang; D'Agati, Vivette; Schmidt, Ann Marie; Ramasamy, Ravichandran
2007 Dec;7(8):699-710, Current molecular medicine
— id: 130823, year: 2007, vol: 7, page: 699, stat: Journal Article,

Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury
Bucciarelli, Loredana G; Kaneko, Michiyo; Ananthakrishnan, Radha; Harja, Evis; Lee, Larisse K; Hwang, Yuying C; Lerner, Shulamit; Bakr, Soliman; Li, Qing; Lu, Yan; Song, Fei; Qu, Wu; Gomez, Teodoro; Zou, Yu Shan; Yan, Shi Fang; Schmidt, Ann Marie; Ramasamy, Ravichandran
2006 Mar 7;113(9):1226-1234, Circulation
— id: 130801, year: 2006, vol: 113, page: 1226, stat: Journal Article,

Blockade of the receptor for advanced glycation end products attenuates acetaminophen-induced hepatotoxicity in mice
Ekong, Udeme; Zeng, Shan; Dun, Hao; Feirt, Nikki; Guo, Jiancheng; Ippagunta, Nikalesh; Guarrera, James V; Lu, Yan; Weinberg, Alan; Qu, Wu; Ramasamy, Ravichandran; Schmidt, Ann Marie; Emond, Jean C
2006 Apr;21(4):682-688, Journal of gastroenterology & hepatology
— id: 130829, year: 2006, vol: 21, page: 682, stat: Journal Article,

Methylglyoxal comes of AGE
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2006 Jan 27;124(2):258-260, Cell
— id: 130830, year: 2006, vol: 124, page: 258, stat: Journal Article,

Sphingosine-1-phosphate: waging a battle in the diabetic blood vessel
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2006 Sep 29;99(7):669-671, Circulation research
— id: 130827, year: 2006, vol: 99, page: 669, stat: Journal Article,

The ligand/RAGE axis: lighting the fuse and igniting vascular stress
Yan, Shi Fang; Naka, Yoshifumi; Hudson, Barry I; Herold, Kevan; Yan, Shi Du; Ramasamy, Ravichandran; Schmidt, Ann Marie
2006 May;8(3):232-239, Current atherosclerosis reports
— id: 130828, year: 2006, vol: 8, page: 232, stat: Journal Article,

JAK-STAT pathway in cardiac ischemic stress
Ananthakrishnan, Radha; Hallam, Kellie; Li, Qing; Ramasamy, Ravichandran
2005 Nov;43(5):353-356, Vascular pharmacology
— id: 130843, year: 2005, vol: 43, page: 353, stat: Journal Article,

Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury
Hwang, Yuying C; Shaw, Sean; Kaneko, Michiyo; Redd, Heather; Marrero, Mario B; Ramasamy, Ravichandran
2005 May;19(7):795-797, FASEB journal
— id: 130840, year: 2005, vol: 19, page: 795, stat: Journal Article,

Aldose reductase and AGE-RAGE pathways: key players in myocardial ischemic injury
Kaneko, Michiyo; Bucciarelli, Loredana; Hwang, Yuying C; Lee, Larisee; Yan, Shi Fang; Schmidt, Ann Marie; Ramasamy, Ravichandran
2005 Jun;1043:702-709, Annals of the New York Academy of Sciences
— id: 130802, year: 2005, vol: 1043, page: 702, stat: Journal Article,

Receptor for advanced glycation end products and its ligands: a journey from the complications of diabetes to its pathogenesis
Kim, William; Hudson, Barry I; Moser, Bernhard; Guo, Jiancheng; Rong, Ling Ling; Lu, Yan; Qu, Wu; Lalla, Evanthia; Lerner, Shulamit; Chen, Yali; Yan, Shirley Shi Du; D'Agati, Vivette; Naka, Yoshifumi; Ramasamy, Ravichandran; Herold, Kevan; Yan, Shi Fang; Schmidt, Ann Marie
2005 Jun;1043:553-561, Annals of the New York Academy of Sciences
— id: 130833, year: 2005, vol: 1043, page: 553, stat: Journal Article,

Perfusion of hearts with triglyceride-rich particles reproduces the metabolic abnormalities in lipotoxic cardiomyopathy
Pillutla, Priya; Hwang, Yuying C; Augustus, Ayanna; Yokoyama, Masayoshi; Yagyu, Hiroaki; Johnston, Thomas P; Kaneko, Michiyo; Ramasamy, Ravichandran; Goldberg, Ira J
2005 Jun;288(6):E1229-E1235, American journal of physiology. Endocrinology & metabolism
— id: 130837, year: 2005, vol: 288, page: E1229, stat: Journal Article,

Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation
Ramasamy, Ravichandran; Vannucci, Susan J; Yan, Shirley Shi Du; Herold, Kevan; Yan, Shi Fang; Schmidt, Ann Marie
2005 Jul;15(7):16R-28R, Glycobiology
— id: 130832, year: 2005, vol: 15, page: 16R, stat: Journal Article,

The RAGE axis and endothelial dysfunction: maladaptive roles in the diabetic vasculature and beyond
Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2005 Oct;15(7):237-243, Trends in cardiovascular medicine
— id: 130831, year: 2005, vol: 15, page: 237, stat: Journal Article,

Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice
Vikramadithyan, Reeba K; Hu, Yunying; Noh, Hye-Lim; Liang, Chien-Ping; Hallam, Kellie; Tall, Alan R; Ramasamy, Ravichandran; Goldberg, Ira J
2005 Sep;115(9):2434-2443, Journal of clinical investigation
— id: 130836, year: 2005, vol: 115, page: 2434, stat: Journal Article,

Central role for aldose reductase pathway in myocardial ischemic injury
Hwang, Yuying C; Kaneko, Michiyo; Bakr, Soliman; Liao, Hui; Lu, Yan; Lewis, Erin R; Yan, Shidu; Ii, Setsuko; Itakura, Mitsuo; Rui, Liu; Skopicki, Hal; Homma, Shunichi; Schmidt, Ann Marie; Oates, Peter J; Szabolcs, Matthias; Ramasamy, Ravichandran
2004 Aug;18(11):1192-1199, FASEB journal
— id: 130792, year: 2004, vol: 18, page: 1192, stat: Journal Article,

Aldose reductase: a key player in myocardial ischemic injury
Kaneko, Michiyo; Ramasamy, Ravichandran
2004 Jan;32(1):19-23, Exercise & sport sciences reviews
— id: 130841, year: 2004, vol: 32, page: 19, stat: Journal Article,

RAGE axis: Animal models and novel insights into the vascular complications of diabetes
Naka, Yoshifumi; Bucciarelli, Loredana G; Wendt, Thoralf; Lee, Larisse K; Rong, Ling Ling; Ramasamy, Ravichandran; Yan, Shi Fang; Schmidt, Ann Marie
2004 Aug;24(8):1342-1349, Arteriosclerosis, thrombosis, & vascular biology
— id: 130795, year: 2004, vol: 24, page: 1342, stat: Journal Article,

Metabolic and functional protection by selective inhibition of nitric oxide synthase 2 during ischemia-reperfusion in isolated perfused hearts
Ramasamy, Ravichandran; Hwang, Yuying C; Liu, Yulin; Son, Ni Huiping; Ma, Ningsheng; Parkinson, John; Sciacca, Robert; Albala, Arline; Edwards, Niloo; Szabolcs, Matthias J; Cannon, Paul J
2004 Apr 6;109(13):1668-1673, Circulation
— id: 130778, year: 2004, vol: 109, page: 1668, stat: Journal Article,

RAGE and its ligands: a lasting memory in diabetic complications?
Yan, Shi-Fang; Ramasamy, Ravichandran; Bucciarelli, Loredana G; Wendt, Thoralf; Lee, Larisse K; Hudson, Barry I; Stern, David M; Lalla, Evanthia; DU Yan, Shi; Rong, Ling Ling; Naka, Yoshifumi; Schmidt, Ann Marie
2004 May;1(1):10-20, Diabetes & vascular disease research
— id: 130796, year: 2004, vol: 1, page: 10, stat: Journal Article,

Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders
Hudson, Barry I; Bucciarelli, Loredana G; Wendt, Thoralf; Sakaguchi, Taichi; Lalla, Evanthia; Qu, Wu; Lu, Yan; Lee, Larisse; Stern, David M; Naka, Yoshifumi; Ramasamy, Ravichandran; Yan, Shi Du; Yan, Shi Fang; D'Agati, Vivette; Schmidt, Ann Marie
2003 Nov 1;419(1):80-88, Archives of biochemistry & biophysics. ABB
— id: 130797, year: 2003, vol: 419, page: 80, stat: Journal Article,

Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium
Hwang, Yuying C; Bakr, Soliman; Ellery, Craig A; Oates, Peter J; Ramasamy, Ravichandran
2003 Dec;17(15):2331-2333, FASEB journal
— id: 130793, year: 2003, vol: 17, page: 2331, stat: Journal Article,

Aldose reductase and vascular stress
Ramasamy R; Oates PJ
Diabetes and cardiovascular disease Philadelphia, Pa. ; London : Lippincott Williams & Wilkins, 2003,
— id: 5642, year: 2003, vol: , page: 55, stat: Chapter,

Aldose reductase: a novel target for cardioprotective interventions
Ramasamy, Ravichandran
2003 Nov;4(8):625-632, Current drug targets
— id: 130845, year: 2003, vol: 4, page: 625, stat: Journal Article,

LPS-induced changes in myocardial markers in neonatal rats
Ravindranath, Thyyar M; Goto, Masakatsu; Bakr, Soliman; Ramasamy, Ravi
2003 ;84(4):319-324, Biology of the neonate
— id: 130844, year: 2003, vol: 84, page: 319, stat: Journal Article,

D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease
Tieu, Kim; Perier, Celine; Caspersen, Casper; Teismann, Peter; Wu, Du-Chu; Yan, Shi-Du; Naini, Ali; Vila, Miquel; Jackson-Lewis, Vernice; Ramasamy, Ravichandran; Przedborski, Serge
2003 Sep;112(6):892-901, Journal of clinical investigation
— id: 130842, year: 2003, vol: 112, page: 892, stat: Journal Article,

Glucose, glycation, and RAGE: implications for amplification of cellular dysfunction in diabetic nephropathy
Wendt, Thoralf; Tanji, Nozomu; Guo, Jiancheng; Hudson, Barry I; Bierhaus, Angelika; Ramasamy, Ravichandran; Arnold, Bernd; Nawroth, Peter P; Yan, Shi Fang; D'Agati, Vivette; Schmidt, Ann Marie
2003 May;14(5):1383-1395, Journal of the American Society of Nephrology
— id: 130798, year: 2003, vol: 14, page: 1383, stat: Journal Article,

Glycation, inflammation, and RAGE: a scaffold for the macrovascular complications of diabetes and beyond
Yan, Shi Fang; Ramasamy, Ravichandran; Naka, Yoshifumi; Schmidt, Ann Marie
2003 Dec 12;93(12):1159-1169, Circulation research
— id: 130834, year: 2003, vol: 93, page: 1159, stat: Journal Article,

Synthesis and initial evaluation of 17-(11)C-heptadecanoic acid for measurement of myocardial fatty acid metabolism
Collier, T Lee; Hwang, Yuying; Ramasamy, Ravichandran; Sciacca, Robert R; Hickey, Kathleen T; Simpson, Norman R; Bergmann, Steven R
2002 Dec;43(12):1707-1714, Journal of nuclear medicine
— id: 130767, year: 2002, vol: 43, page: 1707, stat: Journal Article,

Relative importance of enhanced glucose uptake versus attenuation of long-chain acyl carnitines in protecting ischemic myocardium
Hwang, Yuying C; Bakr, Soliman; Ramasamy, Ravichandran; Bergmann, Steven R
2002 Sep;13(6):313-318, Coronary artery disease
— id: 130768, year: 2002, vol: 13, page: 313, stat: Journal Article,

Aldose reductase activation is a key component of myocardial response to ischemia
Hwang, Yuying C; Sato, Sanai; Tsai, Jen-Yue; Yan, ShiDu; Bakr, Soliman; Zhang, Huiping; Oates, Peter J; Ramasamy, Ravichandran
2002 Feb;16(2):243-245, FASEB journal
— id: 130794, year: 2002, vol: 16, page: 243, stat: Journal Article,

Elucidation of the thromboregulatory role of CD39/ectoapyrase in the ischemic brain
Pinsky, David J; Broekman, M Johan; Peschon, Jacques J; Stocking, Kim L; Fujita, Tomoyuki; Ramasamy, Ravichandran; Connolly, E Sander Jr; Huang, Judy; Kiss, Szilard; Zhang, Yuan; Choudhri, Tanvir F; McTaggart, Ryan A; Liao, Hui; Drosopoulos, Joan H F; Price, Virginia L; Marcus, Aaron J; Maliszewski, Charles R
2002 Apr;109(8):1031-1040, Journal of clinical investigation
— id: 130846, year: 2002, vol: 109, page: 1031, stat: Journal Article,

Adjunctive protection of ischemic myocardium by modification of metabolism
Ramasamy R; Bergmann SR
Challenges in acute coronary syndromes Malden, MA : Blackwell Science, 2001,
— id: 5641, year: 2001, vol: , page: 253, stat: Chapter,

Protection of ischemic hearts by high glucose is mediated, in part, by GLUT-4
Ramasamy, R; Hwang, Y C; Whang, J; Bergmann, S R
2001 Jul;281(1):H290-H297, American journal of physiology. Heart & circulatory physiology
— id: 130771, year: 2001, vol: 281, page: H290, stat: Journal Article,

Protection of ischemic hearts perfused with an anion exchange inhibitor, DIDS, is associated with beneficial changes in substrate metabolism
Ramasamy, R; Hwang, Y; Bakr, S; Bergmann, S R
2001 Aug 1;51(2):275-282, Cardiovascular research
— id: 130770, year: 2001, vol: 51, page: 275, stat: Journal Article,

Fasting limits the increase in intracellular calcium during ischemia in isolated rat hearts
Ramasamy, R; Liu, H; Cherednichenko, G; Schaefer, S
2001 Sep;96(5):463-470, Basic research in cardiology
— id: 130781, year: 2001, vol: 96, page: 463, stat: Journal Article,

Protection of ischemic myocardium in diabetics by inhibition of electroneutral Na+-K+-2Cl- cotransporter
Ramasamy, R; Payne, J A; Whang, J; Bergmann, S R; Schaefer, S
2001 Aug;281(2):H515-H522, American journal of physiology. Heart & circulatory physiology
— id: 130769, year: 2001, vol: 281, page: H515, stat: Journal Article,

Enalaprilat attenuates ischemic rises in intracellular sodium in the isolated rat heart via the bradykinin receptor
Whang, J; Ramasamy, R; Dizon, J M; Bergmann, S R
2001 ;3(1):27-34, Journal of cardiovascular magnetic resonance
— id: 130772, year: 2001, vol: 3, page: 27, stat: Journal Article,

Amyloid beta -peptide-binding alcohol dehydrogenase is a component of the cellular response to nutritional stress
Du Yan, S; Zhu, Y; Stern, E D; Hwang, Y C; Hori, O; Ogawa, S; Frosch, M P; Connolly, E S Jr; McTaggert, R; Pinsky, D J; Clarke, S; Stern, D M; Ramasamy, R
2000 Sep 1;275(35):27100-27109, Journal of biological chemistry
— id: 130780, year: 2000, vol: 275, page: 27100, stat: Journal Article,

Acute elevations of plasma asymmetric dimethylarginine and impaired endothelial function in response to a high-fat meal in patients with type 2 diabetes
Fard, A; Tuck, C H; Donis, J A; Sciacca, R; Di Tullio, M R; Wu, H D; Bryant, T A; Chen, N T; Torres-Tamayo, M; Ramasamy, R; Berglund, L; Ginsberg, H N; Homma, S; Cannon, P J
2000 Sep;20(9):2039-2044, Arteriosclerosis, thrombosis, & vascular biology
— id: 130779, year: 2000, vol: 20, page: 2039, stat: Journal Article,

Fructose-2,6-bisphosphate, a potent stimulator of phosphofructokinase, is increased by high exogenous glucose perfusion
Salaris, S C; Ramasamy, R; Bergmann, S R
2000 May;11(3):279-286, Coronary artery disease
— id: 130773, year: 2000, vol: 11, page: 279, stat: Journal Article,

Niacin protects the isolated heart from ischemia-reperfusion injury
Trueblood, N A; Ramasamy, R; Wang, L F; Schaefer, S
2000 Aug;279(2):H764-H771, American journal of physiology. Heart & circulatory physiology
— id: 130774, year: 2000, vol: 279, page: H764, stat: Journal Article,

Repetitive acidosis protects the ischemic heart: implications for mechanisms in preconditioned hearts
Lundmark, J A; Trueblood, N; Wang, L F; Ramasamy, R; Schaefer, S
1999 Apr;31(4):907-917, Journal of molecular & cellular cardiology
— id: 130775, year: 1999, vol: 31, page: 907, stat: Journal Article,

Chelerythrine increases Na-K-ATPase activity and limits ischemic injury in isolated rat hearts
Lundmark, J L; Ramasamy, R; Vulliet, P R; Schaefer, S
1999 Sep;277(3 Pt 2):H999-H1006, American journal of physiology
— id: 130782, year: 1999, vol: 277, page: H999, stat: Journal Article,

Attenuation of ischemia induced increases in sodium and calcium by the aldose reductase inhibitor zopolrestat
Ramasamy, R; Liu, H; Oates, P J; Schaefer, S
1999 Apr;42(1):130-139, Cardiovascular research
— id: 130784, year: 1999, vol: 42, page: 130, stat: Journal Article,

Inhibition of Na+-H+ exchanger protects diabetic and non-diabetic hearts from ischemic injury: insight into altered susceptibility of diabetic hearts to ischemic injury
Ramasamy, R; Schaefer, S
1999 Apr;31(4):785-797, Journal of molecular & cellular cardiology
— id: 130785, year: 1999, vol: 31, page: 785, stat: Journal Article,

Regulation of glycogen utilization in ischemic hearts after 24 hours of fasting
Wang, L F; Ramasamy, R; Schaefer, S
1999 Jun;42(3):644-650, Cardiovascular research
— id: 130783, year: 1999, vol: 42, page: 644, stat: Journal Article,

Catalytically inactive lipoprotein lipase expression in muscle of transgenic mice increases very low density lipoprotein uptake: direct evidence that lipoprotein lipase bridging occurs in vivo
Merkel, M; Kako, Y; Radner, H; Cho, I S; Ramasamy, R; Brunzell, J D; Goldberg, I J; Breslow, J L
1998 Nov 10;95(23):13841-13846, Proceedings of the National Academy of Sciences of the United States of America
— id: 130838, year: 1998, vol: 95, page: 13841, stat: Journal Article,

Metabolic effects of aldose reductase inhibition during low-flow ischemia and reperfusion
Ramasamy, R; Trueblood, N; Schaefer, S
1998 Jul;275(1 Pt 2):H195-H203, American journal of physiology
— id: 130776, year: 1998, vol: 275, page: H195, stat: Journal Article,

Aldose reductase inhibition improves altered glucose metabolism of isolated diabetic rat hearts
Trueblood, N; Ramasamy, R
1998 Jul;275(1 Pt 2):H75-H83, American journal of physiology
— id: 130777, year: 1998, vol: 275, page: H75, stat: Journal Article,

Aldose reductase inhibition protects diabetic and nondiabetic rat hearts from ischemic injury
Ramasamy, R; Oates, P J; Schaefer, S
1997 Feb;46(2):292-300, Diabetes
— id: 130788, year: 1997, vol: 46, page: 292,