Biosketch / Results /

Prodromos Parasoglou

Assistant Professor, Department of Radiology

Contact Info

Address
660 First Avenue
New York, NY 10016

212-263-2700
Prodromos.Parasoglou@med.nyu.edu

Research Summary

My laboratory is part of the Department of Radiology, Center for Advanced Imaging Innovation and Research, at New York University School of Medicine. I am fortunate to benefit from state-of-the-art facilities and equipment as well as a strong and vibrant research community.

My research focuses on the development and evaluation of new hardware and software that allows us to perform high quality multinuclear magnetic resonance measurements in the human tissue. Multinuclear magnetic resonance imaging (MRI) and spectroscopy (MRS) can assess metabolic function in the human tissue. Phosphorus (31P) MR can probe specific biological processes directly involved in mitochondrial energy metabolism. Impairments in energy metabolism occur in many diseases including type 2 diabetes, Alzheimer’s disease, bipolar disorders, and schizophrenia, and can lead to complications such as cognitive impairment or limb amputation.

Through the development of new, highly sensitive, and quantitative MR techniques we have a unique opportunity to improve our understanding of metabolic abnormalities associated with many diseases, identify new targets for treatment, and test efficacy of new pharmacological agents.

Research Keywords

development of magnetic resonance imaging and spectroscopy tools for studying human metabolism in vivo, MRI, MRS, metabolic imaging, metabolism

A low-cost Mr compatible ergometer to assess post-exercise phosphocreatine recovery kinetics
Naimon, Niels D; Walczyk, Jerzy; Babb, James S; Khegai, Oleksandr; Che, Xuejiao; Alon, Leeor; Regatte, Ravinder R; Brown, Ryan; Parasoglou, Prodromos. A low-cost Mr compatible ergometer to assess post-exercise phosphocreatine recovery kinetics. MAGMA (European Society for Magnetic Resonance in Medicine & Biology). 2017 Jan 4;:?-? (2386752)

Magnetic Resonance Imaging of Phosphocreatine and Determination of BOLD Kinetics in Lower Extremity Muscles using a Dual-Frequency Coil Array
Brown, Ryan; Khegai, Oleksandr; Parasoglou, Prodromos. Magnetic Resonance Imaging of Phosphocreatine and Determination of BOLD Kinetics in Lower Extremity Muscles using a Dual-Frequency Coil Array. Scientific reports. 2016 Jul 28;6:30568-30568 (2191212)

A nested phosphorus and proton coil array for brain magnetic resonance imaging and spectroscopy
Brown, Ryan; Lakshmanan, Karthik; Madelin, Guillaume; Parasoglou, Prodromos. A nested phosphorus and proton coil array for brain magnetic resonance imaging and spectroscopy. Neuroimage. 2016 Jan 01;124(Pt A):602-611 (1779282)

High-resolution #T MR imaging of bone microarchitecture and MRI quantification of bone marrow fat and muscle fat in osteoporosis
Agten, C; Welbeck, A; Xia, D; Parasoglou, P; Rajapakse, C; Chen, C; Saha, P; Honig, S; Chang, G. High-resolution #T MR imaging of bone microarchitecture and MRI quantification of bone marrow fat and muscle fat in osteoporosis [Meeting Abstract]. Skeletal radiology. 2016 Aug;45(8):1164-1164 (2204872)

Feasibility of mapping unidirectional Pi-to-ATP fluxes in muscles of the lower leg at 7.0 Tesla
Parasoglou, Prodromos; Xia, Ding; Regatte, Ravinder R. Feasibility of mapping unidirectional Pi-to-ATP fluxes in muscles of the lower leg at 7.0 Tesla. Magnetic resonance in medicine. 2014 Jul 30;:?-? (1500042)