Calvin Q. Pan

Biosketch / Results /

Calvin Pan

Clinical Professor, Department of Medicine

Contact Info

718/888-7728
Calvin.Pan@nyumc.org

Education

1993-1996 — Long Island Jewish Medical Center (Medicine), Residency Training

Research Summary

He is currently a principle investigator for following clinical trials and most protocols enroll patients at the location of 132-21 Forty First Ave, Flushing,NY 11355. ---[1] Protocol # VX11-950-114 Project Title: A Phase 3b Study of 2 Treatment Durations of Telaprevir, PEG-INF (Pegasys), and Ribavirin (Copegus) in Treatment-Naive and Prior Relapser Subjects With Genotype 1 Chronic Hepatitis C and IL28B CC Genotype ---[2] Protocol # EMUMERATE Project Title: Entecavir Utilization, Management, and Efficacy in the United States: A Multi-center Study (ENUMERATE Study) ---[3] Protocol # ML27900 Project Title: An Observational Study of Peginterferon (e.g. Pegasys)-Based Direct Acting Antiviral Triple Therapy in Patients With Chronic Hepatitis C Genotype 1 (Peg Base USA) ---[4] Protocol # IN-US-174-0149 Project Title: A Phase 4, Randomized, Open-label, Active-Controlled, Superiority Study to Evaluate the Efficacy and Safety of Tenofovir Disoproxil Fumarate (TDF) in Combination with Peginterferon a-2a (Pegasys) versus Standard of Care Tenofovir Disoproxil Fumarate Monotherapy or Peginterferon a-2a Monotherapy for 48 Weeks in Non-Cirrhotic Subjects with HBeAg-Positive or HBeAg-Negative ---[5] Protocol # IN-US-174-0174 Project Title: Tenofovir Disoproxil Fumarate in Late Pregnancy to Prevent Mother to Child Transmission of Hepatitis B Virus: A Multi-Center, Prospective, Randomized, Open-Label Study. ---[6] Protocol # ISR AI463-254 Project Title: An Observational Study on Proximal Tubular Dysfunction in Asian-American Patients Receiving Tenofovir Disoproxil Fumarate (TDF) or Entecavir (ETV) for HBV Treatment, ---[7] Protocol # HBV TRIAL AI452-005 Project Title: Dose-Ranging Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Pegylated Interferon Lambda (BMS-914143) Monotherapy in Interferon-Naive Patients with Chronic Hepatitis B Virus Infection who are HBeAg-positive ---[8] Protocol # IN-US-174-0156 Project Title: Long-term Observational Study on Anti-HBV Effect of Tenofovir Disoproxil Fumarate (TDF) and Resistance Surveillance in Asian-American Adult Patients Formerly Participating Gilead 123 Studies ---[9] Protocol # BMS AI463-198 Project Title: Clinical Presentation and Outcomes of Chronic Hepatitis B Virus (HBV) Infection in Asian Americans ---[10] Protocol # REALM TRIAL AI463080 Project Title: Randomized, Observational Study of Entecavir to Assess Long-term Outcomes Associated with Nucleoside/Nucleotide Monotherapy for Patients with Chronic HBV Infection

Research Interests

Dr. Pan's research interest is focus on the field of natural history of viral hepatitis, antiviral therapy and the prevention of vertical transmission of hepatitis virus.

Letter: lessons from the 'real-world' entecavir therapy in chronic hepatitis B patients - authors' reply
Ahn, J; Nguyen, M H; Lim, J K; Lee, H M; Pan, C Q; Lok, A S. Letter: lessons from the 'real-world' entecavir therapy in chronic hepatitis B patients - authors' reply [Letter]. Alimentary pharmacology & therapeutics. 2016 Apr ;43(7):847-848 (2006322)

Lower Observed Hepatocellular Carcinoma Incidence in Chronic Hepatitis B Patients Treated With Entecavir: Results of the ENUMERATE Study
Ahn, Joseph; Lim, Joseph K; Lee, Hannah M; Lok, Anna S; Nguyen, Mindie; Pan, Calvin Q; Mannalithara, Ajitha; Te, Helen; Reddy, K Rajender; Trinh, Huy; Chu, Danny; Tran, Tram; Lau, Daryl; Leduc, Truong-Sinh; Min, Albert; Trong Le, Loc; Bae, Ho; Van Tran, Sang; Do, Son; Hann, Hie-Won L; Wong, Clifford; Han, Steven; Pillai, Anjana; Park, James S; Tong, Myron; Scaglione, Steve; Woog, Jocelyn; Kim, W Ray. Lower Observed Hepatocellular Carcinoma Incidence in Chronic Hepatitis B Patients Treated With Entecavir: Results of the ENUMERATE Study. American journal of gastroenterology. 2016 Jun 21;:?-? (2159082)

Randomized phase II study of GS-4774 as a therapeutic vaccine in virally suppressed patients with chronic hepatitis B
Lok, Anna S; Pan, Calvin Q; Han, Steven-Huy B; Trinh, Huy N; Fessel, W Jeffrey; Rodell, Timothy; Massetto, Benedetta; Lin, Lanjia; Gaggar, Anuj; Subramanian, G Mani; McHutchison, John G; Ferrari, Carlo; Lee, Hannah; Gordon, Stuart C; Gane, Ed J. Randomized phase II study of GS-4774 as a therapeutic vaccine in virally suppressed patients with chronic hepatitis B. Journal of hepatology. 2016 May 19;:?-? (2114842)

Tenofovir to Prevent Hepatitis B Transmission in Mothers with High Viral Load
Pan, Calvin Q; Duan, Zhongping; Dai, Erhei; Zhang, Shuqin; Han, Guorong; Wang, Yuming; Zhang, Huaihong; Zou, Huaibin; Zhu, Baoshen; Zhao, Wenjing; Jiang, Hongxiu. Tenofovir to Prevent Hepatitis B Transmission in Mothers with High Viral Load. New England journal of medicine. 2016 Jun;374(24):2324-2334 (2143352)

Entecavir safety and effectiveness in a national cohort of treatment-naive chronic hepatitis B patients in the
Ahn, J; Lee, H M; Lim, J K; Pan, C Q; Nguyen, M H; Ray Kim, W; Mannalithara, A; Trinh, H; Chu, D; Tran, T; Min, A; Do, S; Te, H; Reddy, K R; Lok, A S. Entecavir safety and effectiveness in a national cohort of treatment-naive chronic hepatitis B patients in the. Alimentary pharmacology & therapeutics. 2015 Oct 28;43(1):134-144 (1869532)