Biosketch / Results /

Stephen Oliver

Adjunct Assistant Professor, Department of Medicine

Contact Info



1988 — Univ of Michigan, Medical Education

Research Summary

This project studies the immune modulatory effects of the drug thalidomide on the fibrosis of scleroderma. The centerpiece of the study is a 1 year, double blind, placebo controlled clinical trial of thalidomide in scleroderma. Outcome measures include procollagen mRNA in serial skin biopsies as well as immunohistochemistry data, plasma cytokine levels, and flow cytometry assessment of blood cell subsets and Th1/Th2 immune responses. Additional studies include thalidomide''s effects on in vitro collagen production by dermal fibroblasts.

Research Interests

Scleroderma, Sarcoidosis, Dendritic Cells, Th1/Th2 Immunity

Apremilast for discoid lupus erythematosus: results of a phase 2, open-label, single-arm, pilot study
De Souza, Aieska; Strober, Bruce E; Merola, Joseph F; Oliver, Stephen; Franks, Andrew G
2012-11-25; 1545-9616,Journal of drugs in dermatology : JDD - id: 182232, year: 2012 Journal Article

Restraint stress fails to modulate cutaneous hypersensitivity responses in mice lacking the adenosine A1 receptor
Oliver, Stephen J; Mathew, Sneha; Wilder, Tuere F; Cronstein, Bruce N
2012-02-05; 1573-9546,Purinergic signalling - id: 130916, year: 2011

Production of adenosine by regulatory T cells through CD39 blocks adherence of effector T cells to vascular endothelium and thus abrogates contact hypersensitivity reactions
Ring, S; Oliver, S; Cronstein, B; Enk, A; Mahnke, K
2012-02-05; 1573-9538,Purinergic signalling - id: 109828, year: 2010

Plasma BDNF is reduced among middle-aged and elderly women with impaired insulin function: evidence of a compensatory mechanism
Arentoft, Alyssa; Sweat, Victoria; Starr, Vanessa; Oliver, Stephen; Hassenstab, Jason; Bruehl, Hannah; Tirsi, Aziz; Javier, Elizabeth; McHugh, Pauline F; Convit, Antonio
2012-02-05; 1090-2147,Brain & cognition - id: 101886, year: 2009 Journal Article

Response to Comment on "The Anergic State in Sarcoidosis Is Associated with Diminished Dendritic Cell Function"
Oliver, SJ
2012-02-05; 0022-1767,Journal of immunology (1950) - id: 97774, year: 2009