Ralph A Nixon

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Ralph A Nixon, M.D., Ph.D.

Professor; Dir Siberstein Institute
Departments of Psychiatry (Ctr of Brain Health) and Cell Biology (Cell Biology)

Clinical Addresses

145 EAST 32ND STREET
5TH FLOOR
NEW YORK, NY 10016
Phone: 212-263-0731

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Medical Specialties

Psychiatry

Director of Center of Excellence for Brain Aging, Executive Director of The Pearl Barlow Center for Memory Evaluation and Treatment.; Dr. Nixon received his Ph.D. in Cell Biology from Harvard University in 1974.;

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Education

1973-1976 — University of Vermont College of Medicine, Medical Education
1976-1977 — Massachusetts General Hospital (Medicine), Internship
1976-1979 — Massachusetts General Hospital (Psychiatry), Residency Training
1979-1980 — Mclean Hospital (Psychiatry), Residency Training

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Overexpression of the calpain-specific inhibitor calpastatin reduces human alpha-Synuclein processing, aggregation and synaptic impairment in [A30P]alphaSyn transgenic mice
Diepenbroek, Meike; Casadei, Nicolas; Esmer, Hakan; Saido, Takaomi C; Takano, Jiro; Kahle, Philipp J; Nixon, Ralph A; Rao, Mala V; Melki, Ronald; Pieri, Laura; Helling, Stefan; Marcus, Katrin; Krueger, Rejko; Masliah, Eliezer; Riess, Olaf; Nuber, Silke
2014 Aug;23(15):3975-3989, Human molecular genetics
— id: 1085982, year: 2014, vol: 23, page: 3975, stat: Journal Article,

Alzheimer neurodegeneration, autophagy, and Abeta secretion: The ins and outs (comment on DOI 10.1002/bies.201400002)
Nixon, Ralph A
2014 Jun;36(6):547-547, Bioessays
— id: 996942, year: 2014, vol: 36, page: 547, stat: Journal Article,

Specific Calpain Inhibition by Calpastatin Prevents Tauopathy and Neurodegeneration and Restores Normal Lifespan in Tau P301L Mice
Rao, Mala V; McBrayer, Mary Kate; Campbell, Jabbar; Kumar, Asok; Hashim, Audrey; Sershen, Henry; Stavrides, Philip H; Ohno, Masuo; Hutton, Michael; Nixon, Ralph A
2014 Jul;34(28):9222-9234, Journal of neuroscience
— id: 1074822, year: 2014, vol: 34, page: 9222, stat: Journal Article,

Spared piriform cortical single-unit odor processing and odor discrimination in the tg2576 mouse model of Alzheimer's disease
Xu, Wenjin; Lopez-Guzman, Mirielle; Schoen, Chelsea; Fitzgerald, Shane; Lauer, Stephanie L; Nixon, Ralph A; Levy, Efrat; Wilson, Donald A
2014 ;9(9):e106431-e106431 e106431, PLoS one
— id: 1173742, year: 2014, vol: 9, page: e106431, stat: Journal Article,

Lysosomal NEU1 deficiency affects amyloid precursor protein levels and amyloid-beta secretion via deregulated lysosomal exocytosis
Annunziata, Ida; Patterson, Annette; Helton, Danielle; Hu, Huimin; Moshiach, Simon; Gomero, Elida; Nixon, Ralph; d'Azzo, Alessandra
2013 ;4:2734-2734, Nature communications
— id: 1085972, year: 2013, vol: 4, page: 2734, stat: Journal Article,

Lysosome and calcium dysregulation in Alzheimer's disease: Partners in crime
McBrayer, M; Nixon, RA
2013 ;41(6):1495-1502, Transactions (Biochemical Society (Great Britain))
— id: 788352, year: 2013, vol: 41, page: 1495, stat: Journal Article,

Immunization targeting a minor plaque constituent clears beta-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model
Morales-Corraliza, Jose; Schmidt, Stephen D; Mazzella, Matthew J; Berger, Jason D; Wilson, Donald A; Wesson, Daniel W; Jucker, Mathias; Levy, Efrat; Nixon, Ralph A; Mathews, Paul M
2013 Jan;34(1):137-145, Neurobiology of aging
— id: 180342, year: 2013, vol: 34, page: 137, stat: Journal Article,

The role of autophagy in neurodegenerative disease
Nixon, Ralph A
2013 Aug;19(8):983-997, Nature medicine
— id: 590312, year: 2013, vol: 19, page: 983, stat: Journal Article,

G9a-mediated histone methylation regulates ethanol-induced neurodegeneration in the neonatal mouse brain
Subbanna, Shivakumar; Shivakumar, Madhu; Umapathy, Nagavedi S; Saito, Mariko; Mohan, Panaiyur S; Kumar, Asok; Nixon, Ralph A; Verin, Alexander D; Psychoyos, Delphine; Basavarajappa, Balapal S
2013 Jun;54:475-485, Neurobiology of disease
— id: 369642, year: 2013, vol: 54, page: 475, stat: Journal Article,

Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification
Wolfe, Devin M; Lee, Ju-Hyun; Kumar, Asok; Lee, Sooyeon; Orenstein, Samantha J; Nixon, Ralph A
2013 Jun;37(12):1949-1961, European journal of neuroscience
— id: 427352, year: 2013, vol: 37, page: 1949, stat: Journal Article,

Global Axonal Transport Rates are Unaltered in Htau Mice in vivo
Yuan, Aidong; Kumar, Asok; Sasaki, Takahiro; Duff, Karen; Nixon, Ralph A
2013 Jan;37(3):579-586, Journal of Alzheimer's disease
— id: 542722, year: 2013, vol: 37, page: 579, stat: Journal Article,

Guidelines for the use and interpretation of assays for monitoring autophagy
Klionsky, Daniel J; Abdalla, Fabio C; Abeliovich, Hagai; Abraham, Robert T; Acevedo-Arozena, Abraham; Adeli, Khosrow; Agholme, Lotta; Agnello, Maria; Agostinis, Patrizia; Aguirre-Ghiso, Julio A; Ahn, Hyung Jun; Ait-Mohamed, Ouardia; Ait-Si-Ali, Slimane; Akematsu, Takahiko; Akira, Shizuo; Al-Younes, Hesham M; Al-Zeer, Munir A; Albert, Matthew L; Albin, Roger L; Alegre-Abarrategui, Javier; Aleo, Maria Francesca; Alirezaei, Mehrdad; Almasan, Alexandru; Almonte-Becerril, Maylin; Amano, Atsuo; Amaravadi, Ravi; Amarnath, Shoba; Amer, Amal O; Andrieu-Abadie, Nathalie; Anantharam, Vellareddy; Ann, David K; Anoopkumar-Dukie, Shailendra; Aoki, Hiroshi; Apostolova, Nadezda; Arancia, Giuseppe; Aris, John P; Asanuma, Katsuhiko; Asare, Nana Y O; Ashida, Hisashi; Askanas, Valerie; Askew, David S; Auberger, Patrick; Baba, Misuzu; Backues, Steven K; Baehrecke, Eric H; Bahr, Ben A; Bai, Xue-Yuan; Bailly, Yannick; Baiocchi, Robert; Baldini, Giulia; Balduini, Walter; Ballabio, Andrea; Bamber, Bruce A; Bampton, Edward T W; Banhegyi, Gabor; Bartholomew, Clinton R; Bassham, Diane C; Bast, Robert C Jr; Batoko, Henri; Bay, Boon-Huat; Beau, Isabelle; Bechet, Daniel M; Begley, Thomas J; Behl, Christian; Behrends, Christian; Bekri, Soumeya; Bellaire, Bryan; Bendall, Linda J; Benetti, Luca; Berliocchi, Laura; Bernardi, Henri; Bernassola, Francesca; Besteiro, Sebastien; Bhatia-Kissova, Ingrid; Bi, Xiaoning; Biard-Piechaczyk, Martine; Blum, Janice S; Boise, Lawrence H; Bonaldo, Paolo; Boone, David L; Bornhauser, Beat C; Bortoluci, Karina R; Bossis, Ioannis; Bost, Frederic; Bourquin, Jean-Pierre; Boya, Patricia; Boyer-Guittaut, Michael; Bozhkov, Peter V; Brady, Nathan R; Brancolini, Claudio; Brech, Andreas; Brenman, Jay E; Brennand, Ana; Bresnick, Emery H; Brest, Patrick; Bridges, Dave; Bristol, Molly L; Brookes, Paul S; Brown, Eric J; Brumell, John H; Brunetti-Pierri, Nicola; Brunk, Ulf T; Bulman, Dennis E; Bultman, Scott J; Bultynck, Geert; Burbulla, Lena F; Bursch, Wilfried; Butchar, Jonathan P; Buzgariu, Wanda; Bydlowski, Sergio P; Cadwell, Ken; Cahova, Monika; Cai, Dongsheng; Cai, Jiyang; Cai, Qian; Calabretta, Bruno; Calvo-Garrido, Javier; Camougrand, Nadine; Campanella, Michelangelo; Campos-Salinas, Jenny; Candi, Eleonora; Cao, Lizhi; Caplan, Allan B; Carding, Simon R; Cardoso, Sandra M; Carew, Jennifer S; Carlin, Cathleen R; Carmignac, Virginie; Carneiro, Leticia A M; Carra, Serena; Caruso, Rosario A; Casari, Giorgio; Casas, Caty; Castino, Roberta; Cebollero, Eduardo; Cecconi, Francesco; Celli, Jean; Chaachouay, Hassan; Chae, Han-Jung; Chai, Chee-Yin; Chan, David C; Chan, Edmond Y; Chang, Raymond Chuen-Chung; Che, Chi-Ming; Chen, Ching-Chow; Chen, Guang-Chao; Chen, Guo-Qiang; Chen, Min; Chen, Quan; Chen, Steve S-L; Chen, WenLi; Chen, Xi; Chen, Xiangmei; Chen, Xiequn; Chen, Ye-Guang; Chen, Yingyu; Chen, Yongqiang; Chen, Yu-Jen; Chen, Zhixiang; Cheng, Alan; Cheng, Christopher H K; Cheng, Yan; Cheong, Heesun; Cheong, Jae-Ho; Cherry, Sara; Chess-Williams, Russ; Cheung, Zelda H; Chevet, Eric; Chiang, Hui-Ling; Chiarelli, Roberto; Chiba, Tomoki; Chin, Lih-Shen; Chiou, Shih-Hwa; Chisari, Francis V; Cho, Chi Hin; Cho, Dong-Hyung; Choi, Augustine M K; Choi, DooSeok; Choi, Kyeong Sook; Choi, Mary E; Chouaib, Salem; Choubey, Divaker; Choubey, Vinay; Chu, Charleen T; Chuang, Tsung-Hsien; Chueh, Sheau-Huei; Chun, Taehoon; Chwae, Yong-Joon; Chye, Mee-Len; Ciarcia, Roberto; Ciriolo, Maria R; Clague, Michael J; Clark, Robert S B; Clarke, Peter G H; Clarke, Robert; Codogno, Patrice; Coller, Hilary A; Colombo, Maria I; Comincini, Sergio; Condello, Maria; Condorelli, Fabrizio; Cookson, Mark R; Coombs, Graham H; Coppens, Isabelle; Corbalan, Ramon; Cossart, Pascale; Costelli, Paola; Costes, Safia; Coto-Montes, Ana; Couve, Eduardo; Coxon, Fraser P; Cregg, James M; Crespo, Jose L; Cronje, Marianne J; Cuervo, Ana Maria; Cullen, Joseph J; Czaja, Mark J; D'Amelio, Marcello; Darfeuille-Michaud, Arlette; Davids, Lester M; Davies, Faith E; De Felici, Massimo; de Groot, John F; de Haan, Cornelis A M; De Martino, Luisa; De Milito, Angelo; De Tata, Vincenzo; Debnath, Jayanta; Degterev, Alexei; Dehay, Benjamin; Delbridge, Lea M D; Demarchi, Francesca; Deng, Yi Zhen; Dengjel, Jorn; Dent, Paul; Denton, Donna; Deretic, Vojo; Desai, Shyamal D; Devenish, Rodney J; Di Gioacchino, Mario; Di Paolo, Gilbert; Di Pietro, Chiara; Diaz-Araya, Guillermo; Diaz-Laviada, Ines; Diaz-Meco, Maria T; Diaz-Nido, Javier; Dikic, Ivan; Dinesh-Kumar, Savithramma P; Ding, Wen-Xing; Distelhorst, Clark W; Diwan, Abhinav; Djavaheri-Mergny, Mojgan; Dokudovskaya, Svetlana; Dong, Zheng; Dorsey, Frank C; Dosenko, Victor; Dowling, James J; Doxsey, Stephen; Dreux, Marlene; Drew, Mark E; Duan, Qiuhong; Duchosal, Michel A; Duff, Karen; Dugail, Isabelle; Durbeej, Madeleine; Duszenko, Michael; Edelstein, Charles L; Edinger, Aimee L; Egea, Gustavo; Eichinger, Ludwig; Eissa, N Tony; Ekmekcioglu, Suhendan; El-Deiry, Wafik S; Elazar, Zvulun; Elgendy, Mohamed; Ellerby, Lisa M; Eng, Kai Er; Engelbrecht, Anna-Mart; Engelender, Simone; Erenpreisa, Jekaterina; Escalante, Ricardo; Esclatine, Audrey; Eskelinen, Eeva-Liisa; Espert, Lucile; Espina, Virginia; Fan, Huizhou; Fan, Jia; Fan, Qi-Wen; Fan, Zhen; Fang, Shengyun; Fang, Yongqi; Fanto, Manolis; Fanzani, Alessandro; Farkas, Thomas; Farre, Jean-Claude; Faure, Mathias; Fechheimer, Marcus; Feng, Carl G; Feng, Jian; Feng, Qili; Feng, Youji; Fesus, Laszlo; Feuer, Ralph; Figueiredo-Pereira, Maria E; Fimia, Gian Maria; Fingar, Diane C; Finkbeiner, Steven; Finkel, Toren; Finley, Kim D; Fiorito, Filomena; Fisher, Edward A; Fisher, Paul B; Flajolet, Marc; Florez-McClure, Maria L; Florio, Salvatore; Fon, Edward A; Fornai, Francesco; Fortunato, Franco; Fotedar, Rati; Fowler, Daniel H; Fox, Howard S; Franco, Rodrigo; Frankel, Lisa B; Fransen, Marc; Fuentes, Jose M; Fueyo, Juan; Fujii, Jun; Fujisaki, Kozo; Fujita, Eriko; Fukuda, Mitsunori; Furukawa, Ruth H; Gaestel, Matthias; Gailly, Philippe; Gajewska, Malgorzata; Galliot, Brigitte; Galy, Vincent; Ganesh, Subramaniam; Ganetzky, Barry; Ganley, Ian G; Gao, Fen-Biao; Gao, George F; Gao, Jinming; Garcia, Lorena; Garcia-Manero, Guillermo; Garcia-Marcos, Mikel; Garmyn, Marjan; Gartel, Andrei L; Gatti, Evelina; Gautel, Mathias; Gawriluk, Thomas R; Gegg, Matthew E; Geng, Jiefei; Germain, Marc; Gestwicki, Jason E; Gewirtz, David A; Ghavami, Saeid; Ghosh, Pradipta; Giammarioli, Anna M; Giatromanolaki, Alexandra N; Gibson, Spencer B; Gilkerson, Robert W; Ginger, Michael L; Ginsberg, Henry N; Golab, Jakub; Goligorsky, Michael S; Golstein, Pierre; Gomez-Manzano, Candelaria; Goncu, Ebru; Gongora, Celine; Gonzalez, Claudio D; Gonzalez, Ramon; Gonzalez-Estevez, Cristina; Gonzalez-Polo, Rosa Ana; Gonzalez-Rey, Elena; Gorbunov, Nikolai V; Gorski, Sharon; Goruppi, Sandro; Gottlieb, Roberta A; Gozuacik, Devrim; Granato, Giovanna Elvira; Grant, Gary D; Green, Kim N; Gregorc, Ales; Gros, Frederic; Grose, Charles; Grunt, Thomas W; Gual, Philippe; Guan, Jun-Lin; Guan, Kun-Liang; Guichard, Sylvie M; Gukovskaya, Anna S; Gukovsky, Ilya; Gunst, Jan; Gustafsson, Asa B; Halayko, Andrew J; Hale, Amber N; Halonen, Sandra K; Hamasaki, Maho; Han, Feng; Han, Ting; Hancock, Michael K; Hansen, Malene; Harada, Hisashi; Harada, Masaru; Hardt, Stefan E; Harper, J Wade; Harris, Adrian L; Harris, James; Harris, Steven D; Hashimoto, Makoto; Haspel, Jeffrey A; Hayashi, Shin-ichiro; Hazelhurst, Lori A; He, Congcong; He, You-Wen; Hebert, Marie-Josee; Heidenreich, Kim A; Helfrich, Miep H; Helgason, Gudmundur V; Henske, Elizabeth P; Herman, Brian; Herman, Paul K; Hetz, Claudio; Hilfiker, Sabine; Hill, Joseph A; Hocking, Lynne J; Hofman, Paul; Hofmann, Thomas G; Hohfeld, Jorg; Holyoake, Tessa L; Hong, Ming-Huang; Hood, David A; Hotamisligil, Gokhan S; Houwerzijl, Ewout J; Hoyer-Hansen, Maria; Hu, Bingren; Hu, Chien-An A; Hu, Hong-Ming; Hua, Ya; Huang, Canhua; Huang, Ju; Huang, Shengbing; Huang, Wei-Pang; Huber, Tobias B; Huh, Won-Ki; Hung, Tai-Ho; Hupp, Ted R; Hur, Gang Min; Hurley, James B; Hussain, Sabah N A; Hussey, Patrick J; Hwang, Jung Jin; Hwang, Seungmin; Ichihara, Atsuhiro; Ilkhanizadeh, Shirin; Inoki, Ken; Into, Takeshi; Iovane, Valentina; Iovanna, Juan L; Ip, Nancy Y; Isaka, Yoshitaka; Ishida, Hiroyuki; Isidoro, Ciro; Isobe, Ken-ichi; Iwasaki, Akiko; Izquierdo, Marta; Izumi, Yotaro; Jaakkola, Panu M; Jaattela, Marja; Jackson, George R; Jackson, William T; Janji, Bassam; Jendrach, Marina; Jeon, Ju-Hong; Jeung, Eui-Bae; Jiang, Hong; Jiang, Hongchi; Jiang, Jean X; Jiang, Ming; Jiang, Qing; Jiang, Xuejun; Jiang, Xuejun; Jimenez, Alberto; Jin, Meiyan; Jin, Shengkan; Joe, Cheol O; Johansen, Terje; Johnson, Daniel E; Johnson, Gail V W; Jones, Nicola L; Joseph, Bertrand; Joseph, Suresh K; Joubert, Annie M; Juhasz, Gabor; Juillerat-Jeanneret, Lucienne; Jung, Chang Hwa; Jung, Yong-Keun; Kaarniranta, Kai; Kaasik, Allen; Kabuta, Tomohiro; Kadowaki, Motoni; Kagedal, Katarina; Kamada, Yoshiaki; Kaminskyy, Vitaliy O; Kampinga, Harm H; Kanamori, Hiromitsu; Kang, Chanhee; Kang, Khong Bee; Kang, Kwang Il; Kang, Rui; Kang, Yoon-A; Kanki, Tomotake; Kanneganti, Thirumala-Devi; Kanno, Haruo; Kanthasamy, Anumantha G; Kanthasamy, Arthi; Karantza, Vassiliki; Kaushal, Gur P; Kaushik, Susmita; Kawazoe, Yoshinori; Ke, Po-Yuan; Kehrl, John H; Kelekar, Ameeta; Kerkhoff, Claus; Kessel, David H; Khalil, Hany; Kiel, Jan A K W; Kiger, Amy A; Kihara, Akio; Kim, Deok Ryong; Kim, Do-Hyung; Kim, Dong-Hou; Kim, Eun-Kyoung; Kim, Hyung-Ryong; Kim, Jae-Sung; Kim, Jeong Hun; Kim, Jin Cheon; Kim, John K; Kim, Peter K; Kim, Seong Who; Kim, Yong-Sun; Kim, Yonghyun; Kimchi, Adi; Kimmelman, Alec C; King, Jason S; Kinsella, Timothy J; Kirkin, Vladimir; Kirshenbaum, Lorrie A; Kitamoto, Katsuhiko; Kitazato, Kaio; Klein, Ludger; Klimecki, Walter T; Klucken, Jochen; Knecht, Erwin; Ko, Ben C B; Koch, Jan C; Koga, Hiroshi; Koh, Jae-Young; Koh, Young Ho; Koike, Masato; Komatsu, Masaaki; Kominami, Eiki; Kong, Hee Jeong; Kong, Wei-Jia; Korolchuk, Viktor I; Kotake, Yaichiro; Koukourakis, Michael I; Kouri Flores, Juan B; Kovacs, Attila L; Kraft, Claudine; Krainc, Dimitri; Kramer, Helmut; Kretz-Remy, Carole; Krichevsky, Anna M; Kroemer, Guido; Kruger, Rejko; Krut, Oleg; Ktistakis, Nicholas T; Kuan, Chia-Yi; Kucharczyk, Roza; Kumar, Ashok; Kumar, Raj; Kumar, Sharad; Kundu, Mondira; Kung, Hsing-Jien; Kurz, Tino; Kwon, Ho Jeong; La Spada, Albert R; Lafont, Frank; Lamark, Trond; Landry, Jacques; Lane, Jon D; Lapaquette, Pierre; Laporte, Jocelyn F; Laszlo, Lajos; Lavandero, Sergio; Lavoie, Josee N; Layfield, Robert; Lazo, Pedro A; Le, Weidong; Le Cam, Laurent; Ledbetter, Daniel J; Lee, Alvin J X; Lee, Byung-Wan; Lee, Gyun Min; Lee, Jongdae; Lee, Ju-Hyun; Lee, Michael; Lee, Myung-Shik; Lee, Sug Hyung; Leeuwenburgh, Christiaan; Legembre, Patrick; Legouis, Renaud; Lehmann, Michael; Lei, Huan-Yao; Lei, Qun-Ying; Leib, David A; Leiro, Jose; Lemasters, John J; Lemoine, Antoinette; Lesniak, Maciej S; Lev, Dina; Levenson, Victor V; Levine, Beth; Levy, Efrat; Li, Faqiang; Li, Jun-Lin; Li, Lian; Li, Sheng; Li, Weijie; Li, Xue-Jun; Li, Yan-bo; Li, Yi-Ping; Liang, Chengyu; Liang, Qiangrong; Liao, Yung-Feng; Liberski, Pawel P; Lieberman, Andrew; Lim, Hyunjung J; Lim, Kah-Leong; Lim, Kyu; Lin, Chiou-Feng; Lin, Fu-Cheng; Lin, Jian; Lin, Jiandie D; Lin, Kui; Lin, Wan-Wan; Lin, Weei-Chin; Lin, Yi-Ling; Linden, Rafael; Lingor, Paul; Lippincott-Schwartz, Jennifer; Lisanti, Michael P; Liton, Paloma B; Liu, Bo; Liu, Chun-Feng; Liu, Kaiyu; Liu, Leyuan; Liu, Qiong A; Liu, Wei; Liu, Young-Chau; Liu, Yule; Lockshin, Richard A; Lok, Chun-Nam; Lonial, Sagar; Loos, Benjamin; Lopez-Berestein, Gabriel; Lopez-Otin, Carlos; Lossi, Laura; Lotze, Michael T; Low, Peter; Lu, Binfeng; Lu, Bingwei; Lu, Bo; Lu, Zhen; Luciano, Frederic; Lukacs, Nicholas W; Lund, Anders H; Lynch-Day, Melinda A; Ma, Yong; Macian, Fernando; MacKeigan, Jeff P; Macleod, Kay F; Madeo, Frank; Maiuri, Luigi; Maiuri, Maria Chiara; Malagoli, Davide; Malicdan, May Christine V; Malorni, Walter; Man, Na; Mandelkow, Eva-Maria; Manon, Stephen; Manov, Irena; Mao, Kai; Mao, Xiang; Mao, Zixu; Marambaud, Philippe; Marazziti, Daniela; Marcel, Yves L; Marchbank, Katie; Marchetti, Piero; Marciniak, Stefan J; Marcondes, Mateus; Mardi, Mohsen; Marfe, Gabriella; Marino, Guillermo; Markaki, Maria; Marten, Mark R; Martin, Seamus J; Martinand-Mari, Camille; Martinet, Wim; Martinez-Vicente, Marta; Masini, Matilde; Matarrese, Paola; Matsuo, Saburo; Matteoni, Raffaele; Mayer, Andreas; Mazure, Nathalie M; McConkey, David J; McConnell, Melanie J; McDermott, Catherine; McDonald, Christine; McInerney, Gerald M; McKenna, Sharon L; McLaughlin, BethAnn; McLean, Pamela J; McMaster, Christopher R; McQuibban, G Angus; Meijer, Alfred J; Meisler, Miriam H; Melendez, Alicia; Melia, Thomas J; Melino, Gerry; Mena, Maria A; Menendez, Javier A; Menna-Barreto, Rubem F S; Menon, Manoj B; Menzies, Fiona M; Mercer, Carol A; Merighi, Adalberto; Merry, Diane E; Meschini, Stefania; Meyer, Christian G; Meyer, Thomas F; Miao, Chao-Yu; Miao, Jun-Ying; Michels, Paul A M; Michiels, Carine; Mijaljica, Dalibor; Milojkovic, Ana; Minucci, Saverio; Miracco, Clelia; Miranti, Cindy K; Mitroulis, Ioannis; Miyazawa, Keisuke; Mizushima, Noboru; Mograbi, Baharia; Mohseni, Simin; Molero, Xavier; Mollereau, Bertrand; Mollinedo, Faustino; Momoi, Takashi; Monastyrska, Iryna; Monick, Martha M; Monteiro, Mervyn J; Moore, Michael N; Mora, Rodrigo; Moreau, Kevin; Moreira, Paula I; Moriyasu, Yuji; Moscat, Jorge; Mostowy, Serge; Mottram, Jeremy C; Motyl, Tomasz; Moussa, Charbel E-H; Muller, Sylke; Muller, Sylviane; Munger, Karl; Munz, Christian; Murphy, Leon O; Murphy, Maureen E; Musaro, Antonio; Mysorekar, Indira; Nagata, Eiichiro; Nagata, Kazuhiro; Nahimana, Aimable; Nair, Usha; Nakagawa, Toshiyuki; Nakahira, Kiichi; Nakano, Hiroyasu; Nakatogawa, Hitoshi; Nanjundan, Meera; Naqvi, Naweed I; Narendra, Derek P; Narita, Masashi; Navarro, Miguel; Nawrocki, Steffan T; Nazarko, Taras Y; Nemchenko, Andriy; Netea, Mihai G; Neufeld, Thomas P; Ney, Paul A; Nezis, Ioannis P; Nguyen, Huu Phuc; Nie, Daotai; Nishino, Ichizo; Nislow, Corey; Nixon, Ralph A; Noda, Takeshi; Noegel, Angelika A; Nogalska, Anna; Noguchi, Satoru; Notterpek, Lucia; Novak, Ivana; Nozaki, Tomoyoshi; Nukina, Nobuyuki; Nurnberger, Thorsten; Nyfeler, Beat; Obara, Keisuke; Oberley, Terry D; Oddo, Salvatore; Ogawa, Michinaga; Ohashi, Toya; Okamoto, Koji; Oleinick, Nancy L; Oliver, F Javier; Olsen, Laura J; Olsson, Stefan; Opota, Onya; Osborne, Timothy F; Ostrander, Gary K; Otsu, Kinya; Ou, Jing-hsiung James; Ouimet, Mireille; Overholtzer, Michael; Ozpolat, Bulent; Paganetti, Paolo; Pagnini, Ugo; Pallet, Nicolas; Palmer, Glen E; Palumbo, Camilla; Pan, Tianhong; Panaretakis, Theocharis; Pandey, Udai Bhan; Papackova, Zuzana; Papassideri, Issidora; Paris, Irmgard; Park, Junsoo; Park, Ohkmae K; Parys, Jan B; Parzych, Katherine R; Patschan, Susann; Patterson, Cam; Pattingre, Sophie; Pawelek, John M; Peng, Jianxin; Perlmutter, David H; Perrotta, Ida; Perry, George; Pervaiz, Shazib; Peter, Matthias; Peters, Godefridus J; Petersen, Morten; Petrovski, Goran; Phang, James M; Piacentini, Mauro; Pierre, Philippe; Pierrefite-Carle, Valerie; Pierron, Gerard; Pinkas-Kramarski, Ronit; Piras, Antonio; Piri, Natik; Platanias, Leonidas C; Poggeler, Stefanie; Poirot, Marc; Poletti, Angelo; Pous, Christian; Pozuelo-Rubio, Mercedes; Praetorius-Ibba, Mette; Prasad, Anil; Prescott, Mark; Priault, Muriel; Produit-Zengaffinen, Nathalie; Progulske-Fox, Ann; Proikas-Cezanne, Tassula; Przedborski, Serge; Przyklenk, Karin; Puertollano, Rosa; Puyal, Julien; Qian, Shu-Bing; Qin, Liang; Qin, Zheng-Hong; Quaggin, Susan E; Raben, Nina; Rabinowich, Hannah; Rabkin, Simon W; Rahman, Irfan; Rami, Abdelhaq; Ramm, Georg; Randall, Glenn; Randow, Felix; Rao, V Ashutosh; Rathmell, Jeffrey C; Ravikumar, Brinda; Ray, Swapan K; Reed, Bruce H; Reed, John C; Reggiori, Fulvio; Regnier-Vigouroux, Anne; Reichert, Andreas S; Reiners, John J Jr; Reiter, Russel J; Ren, Jun; Revuelta, Jose L; Rhodes, Christopher J; Ritis, Konstantinos; Rizzo, Elizete; Robbins, Jeffrey; Roberge, Michel; Roca, Hernan; Roccheri, Maria C; Rocchi, Stephane; Rodemann, H Peter; Rodriguez de Cordoba, Santiago; Rohrer, Barbel; Roninson, Igor B; Rosen, Kirill; Rost-Roszkowska, Magdalena M; Rouis, Mustapha; Rouschop, Kasper M A; Rovetta, Francesca; Rubin, Brian P; Rubinsztein, David C; Ruckdeschel, Klaus; Rucker, Edmund B 3rd; Rudich, Assaf; Rudolf, Emil; Ruiz-Opazo, Nelson; Russo, Rossella; Rusten, Tor Erik; Ryan, Kevin M; Ryter, Stefan W; Sabatini, David M; Sadoshima, Junichi; Saha, Tapas; Saitoh, Tatsuya; Sakagami, Hiroshi; Sakai, Yasuyoshi; Salekdeh, Ghasem Hoseini; Salomoni, Paolo; Salvaterra, Paul M; Salvesen, Guy; Salvioli, Rosa; Sanchez, Anthony M J; Sanchez-Alcazar, Jose A; Sanchez-Prieto, Ricardo; Sandri, Marco; Sankar, Uma; Sansanwal, Poonam; Santambrogio, Laura; Saran, Shweta; Sarkar, Sovan; Sarwal, Minnie; Sasakawa, Chihiro; Sasnauskiene, Ausra; Sass, Miklos; Sato, Ken; Sato, Miyuki; Schapira, Anthony H V; Scharl, Michael; Schatzl, Hermann M; Scheper, Wiep; Schiaffino, Stefano; Schneider, Claudio; Schneider, Marion E; Schneider-Stock, Regine; Schoenlein, Patricia V; Schorderet, Daniel F; Schuller, Christoph; Schwartz, Gary K; Scorrano, Luca; Sealy, Linda; Seglen, Per O; Segura-Aguilar, Juan; Seiliez, Iban; Seleverstov, Oleksandr; Sell, Christian; Seo, Jong Bok; Separovic, Duska; Setaluri, Vijayasaradhi; Setoguchi, Takao; Settembre, Carmine; Shacka, John J; Shanmugam, Mala; Shapiro, Irving M; Shaulian, Eitan; Shaw, Reuben J; Shelhamer, James H; Shen, Han-Ming; Shen, Wei-Chiang; Sheng, Zu-Hang; Shi, Yang; Shibuya, Kenichi; Shidoji, Yoshihiro; Shieh, Jeng-Jer; Shih, Chwen-Ming; Shimada, Yohta; Shimizu, Shigeomi; Shintani, Takahiro; Shirihai, Orian S; Shore, Gordon C; Sibirny, Andriy A; Sidhu, Stan B; Sikorska, Beata; Silva-Zacarin, Elaine C M; Simmons, Alison; Simon, Anna Katharina; Simon, Hans-Uwe; Simone, Cristiano; Simonsen, Anne; Sinclair, David A; Singh, Rajat; Sinha, Debasish; Sinicrope, Frank A; Sirko, Agnieszka; Siu, Parco M; Sivridis, Efthimios; Skop, Vojtech; Skulachev, Vladimir P; Slack, Ruth S; Smaili, Soraya S; Smith, Duncan R; Soengas, Maria S; Soldati, Thierry; Song, Xueqin; Sood, Anil K; Soong, Tuck Wah; Sotgia, Federica; Spector, Stephen A; Spies, Claudia D; Springer, Wolfdieter; Srinivasula, Srinivasa M; Stefanis, Leonidas; Steffan, Joan S; Stendel, Ruediger; Stenmark, Harald; Stephanou, Anastasis; Stern, Stephan T; Sternberg, Cinthya; Stork, Bjorn; Stralfors, Peter; Subauste, Carlos S; Sui, Xinbing; Sulzer, David; Sun, Jiaren; Sun, Shi-Yong; Sun, Zhi-Jun; Sung, Joseph J Y; Suzuki, Kuninori; Suzuki, Toshihiko; Swanson, Michele S; Swanton, Charles; Sweeney, Sean T; Sy, Lai-King; Szabadkai, Gyorgy; Tabas, Ira; Taegtmeyer, Heinrich; Tafani, Marco; Takacs-Vellai, Krisztina; Takano, Yoshitaka; Takegawa, Kaoru; Takemura, Genzou; Takeshita, Fumihiko; Talbot, Nicholas J; Tan, Kevin S W; Tanaka, Keiji; Tanaka, Kozo; Tang, Daolin; Tang, Dingzhong; Tanida, Isei; Tannous, Bakhos A; Tavernarakis, Nektarios; Taylor, Graham S; Taylor, Gregory A; Taylor, J Paul; Terada, Lance S; Terman, Alexei; Tettamanti, Gianluca; Thevissen, Karin; Thompson, Craig B; Thorburn, Andrew; Thumm, Michael; Tian, FengFeng; Tian, Yuan; Tocchini-Valentini, Glauco; Tolkovsky, Aviva M; Tomino, Yasuhiko; Tonges, Lars; Tooze, Sharon A; Tournier, Cathy; Tower, John; Towns, Roberto; Trajkovic, Vladimir; Travassos, Leonardo H; Tsai, Ting-Fen; Tschan, Mario P; Tsubata, Takeshi; Tsung, Allan; Turk, Boris; Turner, Lorianne S; Tyagi, Suresh C; Uchiyama, Yasuo; Ueno, Takashi; Umekawa, Midori; Umemiya-Shirafuji, Rika; Unni, Vivek K; Vaccaro, Maria I; Valente, Enza Maria; Van den Berghe, Greet; van der Klei, Ida J; van Doorn, Wouter; van Dyk, Linda F; van Egmond, Marjolein; van Grunsven, Leo A; Vandenabeele, Peter; Vandenberghe, Wim P; Vanhorebeek, Ilse; Vaquero, Eva C; Velasco, Guillermo; Vellai, Tibor; Vicencio, Jose Miguel; Vierstra, Richard D; Vila, Miquel; Vindis, Cecile; Viola, Giampietro; Viscomi, Maria Teresa; Voitsekhovskaja, Olga V; von Haefen, Clarissa; Votruba, Marcela; Wada, Keiji; Wade-Martins, Richard; Walker, Cheryl L; Walsh, Craig M; Walter, Jochen; Wan, Xiang-Bo; Wang, Aimin; Wang, Chenguang; Wang, Dawei; Wang, Fan; Wang, Fen; Wang, Guanghui; Wang, Haichao; Wang, Hong-Gang; Wang, Horng-Dar; Wang, Jin; Wang, Ke; Wang, Mei; Wang, Richard C; Wang, Xinglong; Wang, Xuejun; Wang, Ying-Jan; Wang, Yipeng; Wang, Zhen; Wang, Zhigang Charles; Wang, Zhinong; Wansink, Derick G; Ward, Diane M; Watada, Hirotaka; Waters, Sarah L; Webster, Paul; Wei, Lixin; Weihl, Conrad C; Weiss, William A; Welford, Scott M; Wen, Long-Ping; Whitehouse, Caroline A; Whitton, J Lindsay; Whitworth, Alexander J; Wileman, Tom; Wiley, John W; Wilkinson, Simon; Willbold, Dieter; Williams, Roger L; Williamson, Peter R; Wouters, Bradly G; Wu, Chenghan; Wu, Dao-Cheng; Wu, William K K; Wyttenbach, Andreas; Xavier, Ramnik J; Xi, Zhijun; Xia, Pu; Xiao, Gengfu; Xie, Zhiping; Xie, Zhonglin; Xu, Da-zhi; Xu, Jianzhen; Xu, Liang; Xu, Xiaolei; Yamamoto, Ai; Yamamoto, Akitsugu; Yamashina, Shunhei; Yamashita, Michiaki; Yan, Xianghua; Yanagida, Mitsuhiro; Yang, Dun-Sheng; Yang, Elizabeth; Yang, Jin-Ming; Yang, Shi Yu; Yang, Wannian; Yang, Wei Yuan; Yang, Zhifen; Yao, Meng-Chao; Yao, Tso-Pang; Yeganeh, Behzad; Yen, Wei-Lien; Yin, Jia-jing; Yin, Xiao-Ming; Yoo, Ook-Joon; Yoon, Gyesoon; Yoon, Seung-Yong; Yorimitsu, Tomohiro; Yoshikawa, Yuko; Yoshimori, Tamotsu; Yoshimoto, Kohki; You, Ho Jin; Youle, Richard J; Younes, Anas; Yu, Li; Yu, Long; Yu, Seong-Woon; Yu, Wai Haung; Yuan, Zhi-Min; Yue, Zhenyu; Yun, Cheol-Heui; Yuzaki, Michisuke; Zabirnyk, Olga; Silva-Zacarin, Elaine; Zacks, David; Zacksenhaus, Eldad; Zaffaroni, Nadia; Zakeri, Zahra; Zeh, Herbert J 3rd; Zeitlin, Scott O; Zhang, Hong; Zhang, Hui-Ling; Zhang, Jianhua; Zhang, Jing-Pu; Zhang, Lin; Zhang, Long; Zhang, Ming-Yong; Zhang, Xu Dong; Zhao, Mantong; Zhao, Yi-Fang; Zhao, Ying; Zhao, Zhizhuang J; Zheng, Xiaoxiang; Zhivotovsky, Boris; Zhong, Qing; Zhou, Cong-Zhao; Zhu, Changlian; Zhu, Wei-Guo; Zhu, Xiao-Feng; Zhu, Xiongwei; Zhu, Yuangang; Zoladek, Teresa; Zong, Wei-Xing; Zorzano, Antonio; Zschocke, Jurgen; Zuckerbraun, Brian
2012 Apr;8(4):445-544, Autophagy
— id: 181862, year: 2012, vol: 8, page: 445, stat: Journal Article,

Calpastatin modulates APP processing in the brains of beta-amyloid depositing but not wild-type mice
Morales-Corraliza, Jose; Berger, Jason D; Mazzella, Matthew J; Neubert, Thomas A; Ghiso, Jorge; Rao, Mala V; Staufenbiel, Matthias; Nixon, Ralph A; Mathews, Paul M
2012 Jun;33(6):1125.e9-1125.18, Neurobiology of aging
— id: 164336, year: 2012, vol: 33, page: 1125.e9, stat: Journal Article,

Autophagy and Neuronal Cell Death in Neurological Disorders
Nixon, Ralph A.; Yang, Dun-Sheng
2012 OCT;4(10):-, Cold Spring Harbor perspectives in biology
— id: 210072, year: 2012, vol: 4, page: , stat: Journal Article,

The C-Terminal Domains of NF-H and NF-M Subunits Maintain Axonal Neurofilament Content by Blocking Turnover of the Stationary Neurofilament Network
Rao, Mala V; Yuan, Aidong; Campbell, Jabbar; Kumar, Asok; Nixon, Ralph A
2012 ;7(9):e44320-e44320 e44320, PLoS one
— id: 179098, year: 2012, vol: 7, page: e44320, stat: Journal Article,

Abeta measurement by enzyme-linked immunosorbent assay
Schmidt, Stephen D; Mazzella, Matthew J; Nixon, Ralph A; Mathews, Paul M
2012 ;849:507-527, Methods in molecular biology
— id: 166104, year: 2012, vol: 849, page: 507, stat: Journal Article,

Tissue processing prior to analysis of Alzheimer's disease associated proteins and metabolites, including abeta
Schmidt, Stephen D; Nixon, Ralph A; Mathews, Paul M
2012 ;849:493-506, Methods in molecular biology
— id: 166105, year: 2012, vol: 849, page: 493, stat: Journal Article,

Neurofilaments at a glance
Yuan, Aidong; Rao, Mala V; Veeranna; Nixon, Ralph A
2012 Jul;125(Pt 14):3257-3263, Journal of cell science
— id: 179149, year: 2012, vol: 125, page: 3257, stat: Journal Article,

Peripherin is a subunit of peripheral nerve neurofilaments: implications for differential vulnerability of CNS and peripheral nervous system axons
Yuan, Aidong; Sasaki, Takahiro; Kumar, Asok; Peterhoff, Corrinne M; Rao, Mala V; Liem, Ronald K; Julien, Jean-Pierre; Nixon, Ralph A
2012 Jun;32(25):8501-8508, Journal of neuroscience
— id: 170430, year: 2012, vol: 32, page: 8501, stat: Journal Article,

Developmental ethanol enhances histone methyl transferase-mediated epigenetic modification
Basavaraj B.S.; Saito M.; Kumar A.; Nixon R.A.; Verin A.D.; Umapathy N.S.; Subbanna S.
2011 ;35:119A-119A, Alcoholism: clinical & experimental research
— id: 146274, year: 2011, vol: 35, page: 119A, stat: Journal Article,

Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease
Ginsberg, Stephen D; Mufson, Elliott J; Alldred, Melissa J; Counts, Scott E; Wuu, Joanne; Nixon, Ralph A; Che, Shaoli
2011 Oct;42(2):102-110, Journal of chemical neuroanatomy
— id: 136996, year: 2011, vol: 42, page: 102, stat: Journal Article,

Lysosomal Proteolysis Inhibition Selectively Disrupts Axonal Transport of Degradative Organelles and Causes an Alzheimer's-Like Axonal Dystrophy
Lee, Sooyeon; Sato, Yutaka; Nixon, Ralph A
2011 May 25;31(21):7817-7830, Journal of neuroscience
— id: 132892, year: 2011, vol: 31, page: 7817, stat: Journal Article,

Primary lysosomal dysfunction causes cargo-specific deficits of axonal transport leading to Alzheimer-like neuritic dystrophy
Lee, Sooyeon; Sato, Yutaka; Nixon, Ralph A
2011 Dec;7(12):1562-1563, Autophagy
— id: 166106, year: 2011, vol: 7, page: 1562, stat: Journal Article,

Autophagy failure in Alzheimer's disease-locating the primary defect
Nixon RA; Yang DS
2011 Jul;43(1):38-45, Neurobiology of disease
— id: 126480, year: 2011, vol: 43, page: 38, stat: Journal Article,

The Myosin Va Head Domain Binds to the Neurofilament-L Rod and Modulates Endoplasmic Reticulum (ER) Content and Distribution within Axons
Rao, Mala V; Mohan, Panaiyur S; Kumar, Asok; Yuan, Aidong; Montagna, Lee; Campbell, Jabbar; Espreafico, Enilza M; Julien, Jean P; Nixon, Ralph A
2011 ;6(2):e17087-e17087, PLoS one
— id: 126479, year: 2011, vol: 6, page: e17087, stat: Journal Article,

Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments
Veeranna; Yang, Dun-Sheng; Lee, Ju-Hyun; Vinod, K Yaragudri; Stavrides, Philip; Amin, Niranjana D; Pant, Harish C; Nixon, Ralph A
2011 Nov;32(11):2016-2029, Neurobiology of aging
— id: 1085962, year: 2011, vol: 32, page: 2016, stat: Journal Article,

Sensory Network Dysfunction, Behavioral Impairments, and Their Reversibility in an Alzheimer's beta-Amyloidosis Mouse Model
Wesson DW; Borkowski AH; Landreth GE; Nixon RA; Levy E; Wilson DA
2011 Nov 2;31(44):15962-15971, Journal of neuroscience
— id: 145504, year: 2011, vol: 31, page: 15962, stat: Journal Article,

Network dysfunction, olfactory behavior impairments, and their reversibility in an Alzheimer's b-amyloidosis mouse model
Wesson, D W; Borkowski, A H; Landreth, G E; Nixon, R A; Levy, E; Wilson, D A
2011 November 2011;36(9):A6-A6, Chemical senses
— id: 288242, year: 2011, vol: 36, page: A6, stat: Journal Article,

Mechanisms of neural and behavioral dysfunction in Alzheimer's disease
Wesson, Daniel W; Nixon, Ralph A; Levy, Efrat; Wilson, Donald A
2011 Jun;43(3):163-179, Molecular neurobiology
— id: 131960, year: 2011, vol: 43, page: 163, stat: Journal Article,

Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis
Yang, Dun-Sheng; Stavrides, Philip; Mohan, Panaiyur S; Kaushik, Susmita; Kumar, Asok; Ohno, Masuo; Schmidt, Stephen D; Wesson, Daniel W; Bandyopadhyay, Urmi; Jiang, Ying; Pawlik, Monika; Peterhoff, Corrinne M; Yang, Austin J; Wilson, Donald A; St George-Hyslop, Peter; Westaway, David; Mathews, Paul M; Levy, Efrat; Cuervo, Ana M; Nixon, Ralph A
2011 Jul 1;7(7):788-789, Autophagy
— id: 134440, year: 2011, vol: 7, page: 788, stat: Journal Article,

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
Yang, Dun-Sheng; Stavrides, Philip; Mohan, Panaiyur S; Kaushik, Susmita; Kumar, Asok; Ohno, Masuo; Schmidt, Stephen D; Wesson, Daniel; Bandyopadhyay, Urmi; Jiang, Ying; Pawlik, Monika; Peterhoff, Corrinne M; Yang, Austin J; Wilson, Donald A; St George-Hyslop, Peter; Westaway, David; Mathews, Paul M; Levy, Efrat; Cuervo, Ana M; Nixon, Ralph A
2011 Jan;134(Pt 1):258-277, Brain
— id: 126481, year: 2011, vol: 134, page: 258, stat: Journal Article,

The contributions of myelin and axonal caliber to transverse relaxation time in shiverer and neurofilament-deficient mouse models
Dyakin, Victor V; Chen, Yuanxin; Branch, Craig A; Yuan, Aidong; Rao, Mala; Kumar, Asok; Peterhoff, Corrinne M; Nixon, Ralph A
2010 Jul 1;51(3):1098-1105, Neuroimage
— id: 126489, year: 2010, vol: 51, page: 1098, stat: Journal Article,

Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression
Ginsberg, Stephen D; Alldred, Melissa J; Counts, Scott E; Cataldo, Anne M; Neve, Rachael L; Jiang, Ying; Wuu, Joanne; Chao, Moses V; Mufson, Elliott J; Nixon, Ralph A; Che, Shaoli
2010 Nov 15;68(10):885-893, Biological psychiatry
— id: 114169, year: 2010, vol: 68, page: 885, stat: Journal Article,

Regional Selectivity of rab5 and rab7 Protein Upregulation in Mild Cognitive Impairment and Alzheimer's Disease
Ginsberg, Stephen D; Mufson, Elliott J; Counts, Scott E; Wuu, Joanne; Alldred, Melissa J; Nixon, Ralph A; Che, Shaoli
2010 ;22(2):631-639, Journal of Alzheimer's disease
— id: 114587, year: 2010, vol: 22, page: 631, stat: Journal Article,

Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition
Jiang, Ying; Mullaney, Kerry A; Peterhoff, Corrinne M; Che, Shaoli; Schmidt, Stephen D; Boyer-Boiteau, Anne; Ginsberg, Stephen D; Cataldo, Anne M; Mathews, Paul M; Nixon, Ralph A
2010 Jan 26;107(4):1630-1635, Proceedings of the National Academy of Sciences of the United States of America
— id: 126490, year: 2010, vol: 107, page: 1630, stat: Journal Article,

Cystatin C rescues degenerating neurons in a cystatin B-knockout mouse model of progressive myoclonus epilepsy
Kaur, Gurjinder; Mohan, Panaiyur; Pawlik, Monika; DeRosa, Steven; Fajiculay, Jay; Che, Shaoli; Grubb, Anders; Ginsberg, Stephen D; Nixon, Ralph A; Levy, Efrat
2010 Nov;177(5):2256-2267, American journal of pathology
— id: 126484, year: 2010, vol: 177, page: 2256, stat: Journal Article,

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations
Lee, Ju-Hyun; Yu, W Haung; Kumar, Asok; Lee, Sooyeon; Mohan, Panaiyur S; Peterhoff, Corrinne M; Wolfe, Devin M; Martinez-Vicente, Marta; Massey, Ashish C; Sovak, Guy; Uchiyama, Yasuo; Westaway, David; Cuervo, Ana Maria; Nixon, Ralph A
2010 Jun 25;141(7):1146-1158, Cell
— id: 126485, year: 2010, vol: 141, page: 1146, stat: Journal Article,

Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing
Okada, Hirokazu; Zhang, Wenzhu; Peterhoff, Corrinne; Hwang, Jeremy C; Nixon, Ralph A; Ryu, Sung H; Kim, Tae-Wan
2010 Aug;24(8):2783-2794, FASEB journal
— id: 126488, year: 2010, vol: 24, page: 2783, stat: Journal Article,

Amyloid-independent mechanisms in Alzheimer's disease pathogenesis
Pimplikar, Sanjay W; Nixon, Ralph A; Robakis, Nikolaos K; Shen, Jie; Tsai, Li-Huei
2010 Nov 10;30(45):14946-14954, Journal of neuroscience
— id: 126483, year: 2010, vol: 30, page: 14946, stat: Journal Article,

Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
Rothenberg, Cara; Srinivasan, Deepa; Mah, Leann; Kaushik, Susmita; Peterhoff, Corrine M; Ugolino, Janet; Fang, Shengyun; Cuervo, Ana Maria; Nixon, Ralph A; Monteiro, Mervyn J
2010 Aug 15;19(16):3219-3232, Human molecular genetics
— id: 126486, year: 2010, vol: 19, page: 3219, stat: Journal Article,

Rapamycin induces autophagic flux in neurons
Rubinsztein, David C; Nixon, Ralph A
2010 Dec 7;107(49):E181; author reply E182-E181; author reply E182, Proceedings of the National Academy of Sciences of the United States of America
— id: 126482, year: 2010, vol: 107, page: E181; author reply E182, stat: Journal Article,

Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines
Tizon, Belen; Sahoo, Susmita; Yu, Haung; Gauthier, Sebastien; Kumar, Asok R; Mohan, Panaiyur; Figliola, Matthew; Pawlik, Monika; Grubb, Anders; Uchiyama, Yasuo; Bandyopadhyay, Urmi; Cuervo, Ana Maria; Nixon, Ralph A; Levy, Efrat
2010 ;5(3):e9819-e9819, PLoS one
— id: 109506, year: 2010, vol: 5, page: e9819, stat: Journal Article,

Olfactory dysfunction correlates with amyloid-beta burden in an Alzheimer's disease mouse model
Wesson, Daniel W; Levy, Efrat; Nixon, Ralph A; Wilson, Donald A
2010 Jan 13;30(2):505-514, Journal of neuroscience
— id: 126491, year: 2010, vol: 30, page: 505, stat: Journal Article,

Should olfactory dysfunction be used as a biomarker of Alzheimer's disease?
Wesson, Daniel W; Wilson, Donald A; Nixon, Ralph A
2010 May;10(5):633-635, Expert review of neurotherapeutics
— id: 126487, year: 2010, vol: 10, page: 633, stat: Journal Article,

Endocannabinoid system: emerging role from neurodevelopment to neurodegeneration
Basavarajappa, Balapal S; Nixon, Ralph A; Arancio, Ottavio
2009 Apr;9(4):448-462, Mini reviews in medicinal chemistry
— id: 126495, year: 2009, vol: 9, page: 448, stat: Journal Article,

In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model
Chen, Yuanxin; Dyakin, Victor V; Branch, Craig A; Ardekani, Babak; Yang, Dunsheng; Guilfoyle, David N; Peterson, Jesse; Peterhoff, Corrinne; Ginsberg, Stephen D; Cataldo, Anne M; Nixon, Ralph A
2009 Sep;30(9):1453-1465, Neurobiology of aging
— id: 86660, year: 2009, vol: 30, page: 1453, stat: Journal Article,

Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model
Choi, Jennifer H K; Berger, Jason D; Mazzella, Matthew J; Morales-Corraliza, Jose; Cataldo, Anne M; Nixon, Ralph A; Ginsberg, Stephen D; Levy, Efrat; Mathews, Paul M
2009 Sep;110(6):1818-1827, Journal of neurochemistry
— id: 126493, year: 2009, vol: 110, page: 1818, stat: Journal Article,

Complexes of amyloid-beta and cystatin C in the human central nervous system
Mi, Weiqian; Jung, Sonia S; Yu, Haung; Schmidt, Stephen D; Nixon, Ralph A; Mathews, Paul M; Tagliavini, Fabrizio; Levy, Efrat
2009 ;18(2):273-280, Journal of Alzheimer's disease
— id: 126494, year: 2009, vol: 18, page: 273, stat: Journal Article,

Olfactory Perceptual Correlates of b-Amyloid Plaque Burden in Alzheimer's Disease Mouse Models
Wesson, DW; Levy, E; Nixon, RA; Wilson, DA
2009 SEP ;34(7):A26-A27, Chemical senses
— id: 101941, year: 2009, vol: 34, page: A26, stat: Journal Article,

Sniffing out a function for prion proteins
Wilson, Donald A; Nixon, Ralph A
2009 Jan;12(1):7-8, Nature neuroscience
— id: 94316, year: 2009, vol: 12, page: 7, stat: Journal Article,

Monitoring autophagy in Alzheimer's disease and related neurodegenerative diseases
Yang, Dun-Sheng; Lee, Ju-Hyun; Nixon, Ralph A
2009 ;453:111-144, Methods in enzymology
— id: 96862, year: 2009, vol: 453, page: 111, stat: Journal Article,

Neurofilaments form a highly stable stationary cytoskeleton after reaching a critical level in axons
Yuan, Aidong; Sasaki, Takahiro; Rao, Mala V; Kumar, Asok; Kanumuri, Vivek; Dunlop, David S; Liem, Ronald K; Nixon, Ralph A
2009 Sep 9;29(36):11316-11329, Journal of neuroscience
— id: 126492, year: 2009, vol: 29, page: 11316, stat: Journal Article,

Dystrophic serotonergic axons in neurodegenerative diseases
Azmitia, Efrain C; Nixon, Ralph
2008 Jun 27;1217C:185-194, Brain research
— id: 79132, year: 2008, vol: 1217C, page: 185, stat: Journal Article,

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
Boland, Barry; Kumar, Asok; Lee, Sooyeon; Platt, Frances M; Wegiel, Jerzy; Yu, W Haung; Nixon, Ralph A
2008 Jul 2;28(27):6926-6937, Journal of neuroscience
— id: 96865, year: 2008, vol: 28, page: 6926, stat: Journal Article,

Down syndrome fibroblast model of Alzheimer-related endosome pathology: accelerated endocytosis promotes late endocytic defects
Cataldo, Anne M; Mathews, Paul M; Boiteau, Anne Boyer; Hassinger, Linda C; Peterhoff, Corrinne M; Jiang, Ying; Mullaney, Kerry; Neve, Rachael L; Gruenberg, Jean; Nixon, Ralph A
2008 Aug;173(2):370-384, American journal of pathology
— id: 95387, year: 2008, vol: 173, page: 370, stat: Journal Article,

Dysregulation of amyloid precursor protein levels, but not Abeta levels in Ts65Dn mouse brain
Choi, JHK; Diaz, NS; Mazzella, MJ; Ginsberg, SD; Levy, E; Nixon, RA; Mathews, PM
2008 ;4:?-? #T208-T209, Alzheimer's & dementia
— id: 463382, year: 2008, vol: 4, page: ?, stat: Journal Article,

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
Klionsky, Daniel J; Abeliovich, Hagai; Agostinis, Patrizia; Agrawal, Devendra K; Aliev, Gjumrakch; Askew, David S; Baba, Misuzu; Baehrecke, Eric H; Bahr, Ben A; Ballabio, Andrea; Bamber, Bruce A; Bassham, Diane C; Bergamini, Ettore; Bi, Xiaoning; Biard-Piechaczyk, Martine; Blum, Janice S; Bredesen, Dale E; Brodsky, Jeffrey L; Brumell, John H; Brunk, Ulf T; Bursch, Wilfried; Camougrand, Nadine; Cebollero, Eduardo; Cecconi, Francesco; Chen, Yingyu; Chin, Lih-Shen; Choi, Augustine; Chu, Charleen T; Chung, Jongkyeong; Clarke, Peter G H; Clark, Robert S B; Clarke, Steven G; Clave, Corinne; Cleveland, John L; Codogno, Patrice; Colombo, Maria I; Coto-Montes, Ana; Cregg, James M; Cuervo, Ana Maria; Debnath, Jayanta; Demarchi, Francesca; Dennis, Patrick B; Dennis, Phillip A; Deretic, Vojo; Devenish, Rodney J; Di Sano, Federica; Dice, J Fred; Difiglia, Marian; Dinesh-Kumar, Savithramma; Distelhorst, Clark W; Djavaheri-Mergny, Mojgan; Dorsey, Frank C; Droge, Wulf; Dron, Michel; Dunn, William A Jr; Duszenko, Michael; Eissa, N Tony; Elazar, Zvulun; Esclatine, Audrey; Eskelinen, Eeva-Liisa; Fesus, Laszlo; Finley, Kim D; Fuentes, Jose M; Fueyo, Juan; Fujisaki, Kozo; Galliot, Brigitte; Gao, Fen-Biao; Gewirtz, David A; Gibson, Spencer B; Gohla, Antje; Goldberg, Alfred L; Gonzalez, Ramon; Gonzalez-Estevez, Cristina; Gorski, Sharon; Gottlieb, Roberta A; Haussinger, Dieter; He, You-Wen; Heidenreich, Kim; Hill, Joseph A; Hoyer-Hansen, Maria; Hu, Xun; Huang, Wei-Pang; Iwasaki, Akiko; Jaattela, Marja; Jackson, William T; Jiang, Xuejun; Jin, Shengkan; Johansen, Terje; Jung, Jae U; Kadowaki, Motoni; Kang, Chanhee; Kelekar, Ameeta; Kessel, David H; Kiel, Jan A K W; Kim, Hong Pyo; Kimchi, Adi; Kinsella, Timothy J; Kiselyov, Kirill; Kitamoto, Katsuhiko; Knecht, Erwin; Komatsu, Masaaki; Kominami, Eiki; Kondo, Seiji; Kovacs, Attila L; Kroemer, Guido; Kuan, Chia-Yi; Kumar, Rakesh; Kundu, Mondira; Landry, Jacques; Laporte, Marianne; Le, Weidong; Lei, Huan-Yao; Lenardo, Michael J; Levine, Beth; Lieberman, Andrew; Lim, Kah-Leong; Lin, Fu-Cheng; Liou, Willisa; Liu, Leroy F; Lopez-Berestein, Gabriel; Lopez-Otin, Carlos; Lu, Bo; Macleod, Kay F; Malorni, Walter; Martinet, Wim; Matsuoka, Ken; Mautner, Josef; Meijer, Alfred J; Melendez, Alicia; Michels, Paul; Miotto, Giovanni; Mistiaen, Wilhelm P; Mizushima, Noboru; Mograbi, Baharia; Monastyrska, Iryna; Moore, Michael N; Moreira, Paula I; Moriyasu, Yuji; Motyl, Tomasz; Munz, Christian; Murphy, Leon O; Naqvi, Naweed I; Neufeld, Thomas P; Nishino, Ichizo; Nixon, Ralph A; Noda, Takeshi; Nurnberg, Bernd; Ogawa, Michinaga; Oleinick, Nancy L; Olsen, Laura J; Ozpolat, Bulent; Paglin, Shoshana; Palmer, Glen E; Papassideri, Issidora; Parkes, Miles; Perlmutter, David H; Perry, George; Piacentini, Mauro; Pinkas-Kramarski, Ronit; Prescott, Mark; Proikas-Cezanne, Tassula; Raben, Nina; Rami, Abdelhaq; Reggiori, Fulvio; Rohrer, Barbel; Rubinsztein, David C; Ryan, Kevin M; Sadoshima, Junichi; Sakagami, Hiroshi; Sakai, Yasuyoshi; Sandri, Marco; Sasakawa, Chihiro; Sass, Miklos; Schneider, Claudio; Seglen, Per O; Seleverstov, Oleksandr; Settleman, Jeffrey; Shacka, John J; Shapiro, Irving M; Sibirny, Andrei; Silva-Zacarin, Elaine C M; Simon, Hans-Uwe; Simone, Cristiano; Simonsen, Anne; Smith, Mark A; Spanel-Borowski, Katharina; Srinivas, Vickram; Steeves, Meredith; Stenmark, Harald; Stromhaug, Per E; Subauste, Carlos S; Sugimoto, Seiichiro; Sulzer, David; Suzuki, Toshihiko; Swanson, Michele S; Tabas, Ira; Takeshita, Fumihiko; Talbot, Nicholas J; Talloczy, Zsolt; Tanaka, Keiji; Tanaka, Kozo; Tanida, Isei; Taylor, Graham S; Taylor, J Paul; Terman, Alexei; Tettamanti, Gianluca; Thompson, Craig B; Thumm, Michael; Tolkovsky, Aviva M; Tooze, Sharon A; Truant, Ray; Tumanovska, Lesya V; Uchiyama, Yasuo; Ueno, Takashi; Uzcategui, Nestor L; van der Klei, Ida; Vaquero, Eva C; Vellai, Tibor; Vogel, Michael W; Wang, Hong-Gang; Webster, Paul; Wiley, John W; Xi, Zhijun; Xiao, Gutian; Yahalom, Joachim; Yang, Jin-Ming; Yap, George; Yin, Xiao-Ming; Yoshimori, Tamotsu; Yu, Li; Yue, Zhenyu; Yuzaki, Michisuke; Zabirnyk, Olga; Zheng, Xiaoxiang; Zhu, Xiongwei; Deter, Russell L
2008 Feb;4(2):151-175, Autophagy
— id: 156977, year: 2008, vol: 4, page: 151, stat: Journal Article,

Neurodegenerative lysosomal disorders- a continuum from development to late age
Nixon, Ralph A; Yang, Dun-Sheng; Lee, Ju-Hyun
2008 Sep-Oct;4(5):590-599, Autophagy
— id: 79133, year: 2008, vol: 4, page: 590, stat: Journal Article,

Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo
Planel, Emmanuel; Krishnamurthy, Pavan; Miyasaka, Tomohiro; Liu, Li; Herman, Mathieu; Kumar, Asok; Bretteville, Alexis; Figueroa, Helen Y; Yu, Wai Haung; Whittington, Robert A; Davies, Peter; Takashima, Akihiko; Nixon, Ralph A; Duff, Karen E
2008 Nov 26;28(48):12798-12807, Journal of neuroscience
— id: 96863, year: 2008, vol: 28, page: 12798, stat: Journal Article,

Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression
Rao, Mala V; Mohan, Panaiyur S; Peterhoff, Corrinne M; Yang, Dun-Sheng; Schmidt, Stephen D; Stavrides, Philip H; Campbell, Jabbar; Chen, Yuanxin; Jiang, Ying; Paskevich, Peter A; Cataldo, Anne M; Haroutunian, Vahram; Nixon, Ralph A
2008 Nov 19;28(47):12241-12254, Journal of neuroscience
— id: 94362, year: 2008, vol: 28, page: 12241, stat: Journal Article,

Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease
Trinchese, Fabrizio; Fa', Mauro; Liu, Shumin; Zhang, Hong; Hidalgo, Ariel; Schmidt, Stephen D; Yamaguchi, Hisako; Yoshii, Narihiko; Mathews, Paul M; Nixon, Ralph A; Arancio, Ottavio
2008 Aug;118(8):2796-2807, Journal of clinical investigation
— id: 95386, year: 2008, vol: 118, page: 2796, stat: Journal Article,

Neurofilament tail phosphorylation: identity of the RT-97 phosphoepitope and regulation in neurons by cross-talk among proline-directed kinases
Veeranna; Lee, Ju-Hyun; Pareek, Tej K; Jaffee, Howard; Boland, Barry; Vinod, K Yaragudri; Amin, Niranjana; Kulkarni, Ashok B; Pant, Harish C; Nixon, Ralph A
2008 Oct;107(1):35-49, Journal of neurochemistry
— id: 1085952, year: 2008, vol: 107, page: 35, stat: Journal Article,

Neuronal apoptosis and autophagy cross talk in aging PS/APP mice, a model of Alzheimer's disease
Yang, Dun-Sheng; Kumar, Asok; Stavrides, Philip; Peterson, Jesse; Peterhoff, Corrine M; Pawlik, Monika; Levy, Efrat; Cataldo, Anne M; Nixon, Ralph A
2008 Sep;173(3):665-681, American journal of pathology
— id: 86556, year: 2008, vol: 173, page: 665, stat: Journal Article,

Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice
Yuan, Aidong; Kumar, Asok; Peterhoff, Corrinne; Duff, Karen; Nixon, Ralph A
2008 Feb 13;28(7):1682-1687, Journal of neuroscience
— id: 94106, year: 2008, vol: 28, page: 1682, stat: Journal Article,

Cortical plasticity in Alzheimer's disease in humans and rodents
Battaglia, Fortunato; Wang, Hoau-Yan; Ghilardi, M Felice; Gashi, Eleonora; Quartarone, Angelo; Friedman, Eitan; Nixon, Ralph A
2007 Dec 15;62(12):1405-1412, Biological psychiatry
— id: 96868, year: 2007, vol: 62, page: 1405, stat: Journal Article,

Quantitative MRI reveals aging-associated T2 changes in mouse models of Alzheimer's disease
Falangola, M F; Dyakin, V V; Lee, S P; Bogart, A; Babb, J S; Duff, K; Nixon, R; Helpern, J A
2007 May;20(3):343-351, NMR in biomedicine
— id: 91355, year: 2007, vol: 20, page: 343, stat: Journal Article,

Erratum: Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo (Journal of Neurochemistry (2007) 102, (619-626))
Gandy, S; Zhang, Y-W; Ikin, A; Schmidt, SD; Bogush, A; Levy, E; Sheffield, R; Nixon, RA; Liao, F-F; Mathews, PM; Xu, H; Ehrlich, ME
2007 ;103(3):1272-, Journal of neurochemistry
— id: 643112, year: 2007, vol: 103, page: 1272, stat: Journal Article,

Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo (vol 102, pg 619, 2007)
Gandy, S; Zhang, YW; Ikin, A; Schmidt, SD; Bogush, A; Levy, E; Sheffield, R; Nixon, RA; Liao, FF; Mathews, PM; Xu, HX; Ehrlich, ME
2007 NOV ;103(3):1272-1272, Journal of neurochemistry
— id: 74687, year: 2007, vol: 103, page: 1272, stat: Journal Article,

Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo
Gandy, Sam; Zhang, Yun-wu; Ikin, Annat; Schmidt, Stephen D; Bogush, Alexey; Levy, Efrat; Sheffield, Roxanne; Nixon, Ralph A; Liao, Francesca-Fang; Mathews, Paul M; Xu, Huaxi; Ehrlich, Michelle E
2007 Aug;102(3):619-626, Journal of neurochemistry
— id: 95391, year: 2007, vol: 102, page: 619, stat: Journal Article,

Cystatin C inhibits amyloid-beta deposition in Alzheimer's disease mouse models
Mi, Weiqian; Pawlik, Monika; Sastre, Magdalena; Jung, Sonia S; Radvinsky, David S; Klein, Andrew M; Sommer, John; Schmidt, Stephen D; Nixon, Ralph A; Mathews, Paul M; Levy, Efrat
2007 Dec;39(12):1440-1442, Nature genetics
— id: 95389, year: 2007, vol: 39, page: 1440, stat: Journal Article,

Autophagy, amyloidogenesis and Alzheimer disease
Nixon, Ralph A
2007 Dec 1;120(Pt 23):4081-4091, Journal of cell science
— id: 96867, year: 2007, vol: 120, page: 4081, stat: Journal Article,

Neuronal macroautophagy: from development to degeneration
Boland, Barry; Nixon, Ralph A
2006 Oct-Dec;27(5-6):503-519, Molecular aspects of medicine
— id: 72833, year: 2006, vol: 27, page: 503, stat: Journal Article,

Potential compensatory responses through autophagic/lysosomal pathways in neurodegenerative diseases
Butler, David; Nixon, Ralph A; Bahr, Ben A
2006 Jul-Sep;2(3):234-237, Autophagy
— id: 72830, year: 2006, vol: 2, page: 234, stat: Journal Article,

Dysregulation of brain APP in the Ts65Dn Down syndrome mouse
Choi, JHK; Diaz, NS; Mazzella, MJ; Peterson, JN; Cataldo, AM; Ginsberg, SD; Levy, E; Nixon, RA; Mathews, PM
2006 ;2:?-? #S236, Alzheimer's & dementia
— id: 463402, year: 2006, vol: 2, page: ?, stat: Journal Article,

APP expression modulated AD-related endosomal trafficking abnormalities in Down syndrome fibroblasts
Jiang, Y; Mullaney, KA; Che, S; Schmidt, SD; Mathews, PM; Cataldo, AM; Ginsberg, SD; Nixon, RA
2006 ;2:?-? #S250, Alzheimer's & dementia
— id: 463392, year: 2006, vol: 2, page: ?, stat: Journal Article,

Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation
Liang, Jing; Yin, Chaobo; Doong, Howard; Fang, Shengyun; Peterhoff, Corrine; Nixon, Ralph A; Monteiro, Mervyn J
2006 Oct 1;119(Pt 19):4011-4024, Journal of cell science
— id: 72831, year: 2006, vol: 119, page: 4011, stat: Journal Article,

Autophagy in neurodegenerative disease: friend, foe or turncoat?
Nixon, Ralph A
2006 Sep;29(9):528-535, Trends in neurosciences
— id: 72829, year: 2006, vol: 29, page: 528, stat: Journal Article,

Lysosomal system pathways: genes to neurodegeneration in Alzheimer's disease
Nixon, Ralph A; Cataldo, Anne M
2006 ;9(3 Suppl):277-289, Journal of Alzheimer's disease
— id: 126496, year: 2006, vol: 9, page: 277, stat: Journal Article,

Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration
Salehi, Ahmad; Delcroix, Jean-Dominique; Belichenko, Pavel V; Zhan, Ke; Wu, Chengbiao; Valletta, Janice S; Takimoto-Kimura, Ryoko; Kleschevnikov, Alexander M; Sambamurti, Kumar; Chung, Peter P; Xia, Weiming; Villar, Angela; Campbell, William A; Kulnane, Laura Shapiro; Nixon, Ralph A; Lamb, Bruce T; Epstein, Charles J; Stokin, Gorazd B; Goldstein, Lawrence S B; Mobley, William C
2006 Jul 6;51(1):29-42, Neuron
— id: 72832, year: 2006, vol: 51, page: 29, stat: Journal Article,

Deleting the phosphorylated tail domain of the neurofilament heavy subunit does not alter neurofilament transport rate in vivo
Yuan, Aidong; Nixon, Ralph A; Rao, Mala V
2006 Jan 30;393(2-3):264-268, Neuroscience letters
— id: 60252, year: 2006, vol: 393, page: 264, stat: Journal Article,

Alpha-internexin is structurally and functionally associated with the neurofilament triplet proteins in the mature CNS
Yuan, Aidong; Rao, Mala V; Sasaki, Takahiro; Chen, Yuanxin; Kumar, Asok; Liem, Ronald K H; Eyer, Joel; Peterson, Alan C; Julien, Jean-Pierre; Nixon, Ralph A
2006 Sep 27;26(39):10006-10019, Journal of neuroscience
— id: 94108, year: 2006, vol: 26, page: 10006, stat: Journal Article,

Medical bioremediation: prospects for the application of microbial catabolic diversity to aging and several major age-related diseases
de Grey, Aubrey D N J; Alvarez, Pedro J J; Brady, Roscoe O; Cuervo, Ana Maria; Jerome, W Gray; McCarty, Perry L; Nixon, Ralph A; Rittmann, Bruce E; Sparrow, Janet R
2005 Aug;4(3):315-338, Ageing research reviews
— id: 72834, year: 2005, vol: 4, page: 315, stat: Journal Article,

Application of a non-linear image registration algorithm to quantitative analysis of T2 relaxation time in transgenic mouse models of AD pathology
Falangola, M F; Ardekani, B A; Lee, S-P; Babb, J S; Bogart, A; Dyakin, V V; Nixon, R; Duff, K; Helpern, J A
2005 May 15;144(1):91-97, Journal of neuroscience methods
— id: 56353, year: 2005, vol: 144, page: 91, stat: Journal Article,

Histological co-localization of iron in Abeta plaques of PS/APP transgenic mice
Falangola, Maria F; Lee, Sang-Pil; Nixon, Ralph A; Duff, Karen; Helpern, Joseph A
2005 Feb;30(2):201-205, Neurochemical research
— id: 55764, year: 2005, vol: 30, page: 201, stat: Journal Article,

Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases
Mastrangelo, Peter; Mathews, Paul M; Chishti, M Azhar; Schmidt, Stephen D; Gu, Yongjun; Yang, Jing; Mazzella, Matthew J; Coomaraswamy, Janaky; Horne, Patrick; Strome, Bob; Pelly, Heather; Levesque, Georges; Ebeling, Chris; Jiang, Ying; Nixon, Ralph A; Rozmahel, Richard; Fraser, Paul E; St George-Hyslop, Peter; Carlson, George A; Westaway, David
2005 Jun 21;102(25):8972-8977, Proceedings of the National Academy of Sciences of the United States of America
— id: 95396, year: 2005, vol: 102, page: 8972, stat: Journal Article,

Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases
Nixon, Ralph A
2005 Mar;26(3):373-382, Neurobiology of aging
— id: 51387, year: 2005, vol: 26, page: 373, stat: Journal Article,

Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study
Nixon, Ralph A; Wegiel, Jerzy; Kumar, Asok; Yu, Wai Haung; Peterhoff, Corrinne; Cataldo, Anne; Cuervo, Ana Maria
2005 Feb;64(2):113-122, Journal of neuropathology & experimental neurology
— id: 50295, year: 2005, vol: 64, page: 113, stat: Journal Article,

Autophagy and its possible roles in nervous system diseases, damage and repair
Rubinsztein, David C; DiFiglia, Marian; Heintz, Nathaniel; Nixon, Ralph A; Qin, Zheng-Hong; Ravikumar, Brinda; Stefanis, Leonidas; Tolkovsky, Aviva
2005 Apr;1(1):11-22, Autophagy
— id: 72828, year: 2005, vol: 1, page: 11, stat: Journal Article,

Tissue processing prior to protein analysis and amyloid-beta quantitation
Schmidt, Stephen D; Jiang, Ying; Nixon, Ralph A; Mathews, Paul M
2005 ;299:267-278, Methods in molecular biology
— id: 56368, year: 2005, vol: 299, page: 267, stat: Journal Article,

ELISA method for measurement of amyloid-beta levels
Schmidt, Stephen D; Nixon, Ralph A; Mathews, Paul M
2005 ;299:279-297, Methods in molecular biology
— id: 56369, year: 2005, vol: 299, page: 279, stat: Journal Article,

Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease
Yu, W Haung; Cuervo, Ana Maria; Kumar, Asok; Peterhoff, Corrinne M; Schmidt, Stephen D; Lee, Ju-Hyun; Mohan, Panaiyur S; Mercken, Marc; Farmery, Mark R; Tjernberg, Lars O; Jiang, Ying; Duff, Karen; Uchiyama, Yasuo; Naslund, Jan; Mathews, Paul M; Cataldo, Anne M; Nixon, Ralph A
2005 Oct 10;171(1):87-98, Journal of cell biology
— id: 60255, year: 2005, vol: 171, page: 87, stat: Journal Article,

Alzheimer amyloid precursor aspartyl proteinase activity in CHAPSO homogenates of Spodoptera frugiperda cells
Carter, Troy L; Verdile, Giuseppe; Groth, David; Bogush, Alexey; Thomas, Stefani; Shen, Patrick; Fraser, Paul E; Mathews, Paul; Nixon, Ralph A; Ehrlich, Michelle E; Kwok, John B J; St George-Hyslop, Peter; Schofield, Peter; Li, Yueming; Yang, Austin; Martins, Ralph N; Gandy, Sam
2004 Oct-Dec;18(4):261-263, Alzheimer disease & associated disorders
— id: 55765, year: 2004, vol: 18, page: 261, stat: Journal Article,

Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome
Cataldo, Anne M; Petanceska, Suzana; Terio, Nicole B; Peterhoff, Corrinne M; Durham, Robert; Mercken, Marc; Mehta, Pankaj D; Buxbaum, Joseph; Haroutunian, Vahram; Nixon, Ralph A
2004 Nov-Dec;25(10):1263-1272, Neurobiology of aging
— id: 61153, year: 2004, vol: 25, page: 1263, stat: Journal Article,

Presenilin mutations in familial Alzheimer disease and transgenic mouse models accelerate neuronal lysosomal pathology
Cataldo, Anne M; Peterhoff, Corrinne M; Schmidt, Stephen D; Terio, Nicole B; Duff, Karen; Beard, Margaret; Mathews, Paul M; Nixon, Ralph A
2004 Aug;63(8):821-830, Journal of neuropathology & experimental neurology
— id: 95397, year: 2004, vol: 63, page: 821, stat: Journal Article,

MRI assessment of neuropathology in a transgenic mouse model of Alzheimer's disease
Helpern, Joseph A; Lee, Sang-Pil; Falangola, Maria F; Dyakin, Victor V; Bogart, Adam; Ardekani, Babak; Duff, Karen; Branch, Craig; Wisniewski, Thomas; de Leon, Mony J; Wolf, Oliver; O'Shea, Jacqueline; Nixon, Ralph A
2004 Apr;51(4):794-798, Magnetic resonance in medicine
— id: 42285, year: 2004, vol: 51, page: 794, stat: Journal Article,

Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein
Laudon, Hanna; Mathews, Paul M; Karlstrom, Helena; Bergman, Anna; Farmery, Mark R; Nixon, Ralph A; Winblad, Bengt; Gandy, Samuel E; Lendahl, Urban; Lundkvist, Johan; Naslund, Jan
2004 Apr;89(1):44-53, Journal of neurochemistry
— id: 42252, year: 2004, vol: 89, page: 44, stat: Journal Article,

Visualization of beta-amyloid plaques in a transgenic mouse model of Alzheimer's disease using MR microscopy without contrast reagents
Lee, Sang-Pil; Falangola, Maria F; Nixon, Ralph A; Duff, Karen; Helpern, Joseph A
2004 Sep;52(3):538-544, Magnetic resonance in medicine
— id: 47817, year: 2004, vol: 52, page: 538, stat: Journal Article,

Autophagy in Alzheimer's disease pathogenesis
Nixon, RA; Yu, WH; Cuervo, AM; Cataldo, AM; Mathews, PM; Yang, DS; Zheng, P; Peterhoff, CM; Kumar, A; Jiang, Y; Peterson, J; Schmidt, SD; Mohan, P; Duff, K; Hassinger, L; Wegiel, J; Lamb, B
2004 JUL ;25(10):S70-S71, Neurobiology of aging
— id: 47716, year: 2004, vol: 25, page: S70, stat: Journal Article,

Niemann-Pick Type C disease and Alzheimer's disease: the APP-endosome connection fattens up
Nixon, Ralph A
2004 Mar;164(3):757-761, American journal of pathology
— id: 42286, year: 2004, vol: 164, page: 757, stat: Journal Article,

Overexpression of human cystatin C in transgenic mice does not affect levels of endogenous brain amyloid Beta Peptide
Pawlik, Monika; Sastre, Magdalena; Calero, Miguel; Mathews, Paul M; Schmidt, Stephen D; Nixon, Ralph A; Levy, Efrat
2004 ;22(1-2):13-18, Journal of molecular neuroscience
— id: 42253, year: 2004, vol: 22, page: 13, stat: Journal Article,

Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice
Sadowski, Marcin; Pankiewicz, Joanna; Scholtzova, Henrieta; Ji, Yong; Quartermain, David; Jensen, Catrin H; Duff, Karen; Nixon, Ralph A; Gruen, Rand J; Wisniewski, Thomas
2004 May;63(5):418-428, Journal of neuropathology & experimental neurology
— id: 44514, year: 2004, vol: 63, page: 418, stat: Journal Article,

Binding of cystatin C to Alzheimer's amyloid beta inhibits in vitro amyloid fibril formation
Sastre, Magdalena; Calero, Miguel; Pawlik, Monika; Mathews, Paul M; Kumar, Asok; Danilov, Vlatko; Schmidt, Stephen D; Nixon, Ralph A; Frangione, Blas; Levy, Efrat
2004 Oct;25(8):1033-1043, Neurobiology of aging
— id: 46126, year: 2004, vol: 25, page: 1033, stat: Journal Article,

Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease
Veeranna; Kaji T; Boland B; Odrljin T; Mohan P; Basavarajappa BS; Peterhoff C; Cataldo A; Rudnicki A; Amin N; Li BS; Pant HC; Hungund BL; Arancio O; Nixon RA
2004 Oct;165(3):795-805, American journal of pathology
— id: 46128, year: 2004, vol: 165, page: 795, stat: Journal Article,

Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits
Yao, Jun; Petanceska, Suzana S; Montine, Thomas J; Holtzman, David M; Schmidt, Stephen D; Parker, Carolyn A; Callahan, Michael J; Lipinski, William J; Bisgaier, Charles L; Turner, Brian A; Nixon, Ralph A; Martins, Ralph N; Ouimet, Charles; Smith, Jonathan D; Davies, Peter; Laska, Eugene; Ehrlich, Michelle E; Walker, Lary C; Mathews, Paul M; Gandy, Sam
2004 Aug;90(4):1011-1018, Journal of neurochemistry
— id: 56111, year: 2004, vol: 90, page: 1011, stat: Journal Article,

Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for beta-amyloid peptide over-production and localization in Alzheimer's disease
Yu, W H; Kumar, A; Peterhoff, C; Shapiro Kulnane, L; Uchiyama, Y; Lamb, B T; Cuervo, A M; Nixon, R A
2004 Dec;36(12):2531-2540, International journal of biochemistry & cell biology
— id: 61278, year: 2004, vol: 36, page: 2531, stat: Journal Article,

Calpain inhibitors, a treatment for Alzheimer's disease: position paper
Battaglia, Fortunato; Trinchese, Fabrizio; Liu, Shumin; Walter, Sean; Nixon, Ralph A; Arancio, Ottavio
2003 ;20(3):357-362, Journal of molecular neuroscience
— id: 40067, year: 2003, vol: 20, page: 357, stat: Journal Article,

App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of down syndrome
Cataldo, Anne M; Petanceska, Suzana; Peterhoff, Corrinne M; Terio, Nicole B; Epstein, Charles J; Villar, Angela; Carlson, Elaine J; Staufenbiel, Matthias; Nixon, Ralph A
2003 Jul 30;23(17):6788-6792, Journal of neuroscience
— id: 40068, year: 2003, vol: 23, page: 6788, stat: Journal Article,

Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production
Grbovic, Olivera M; Mathews, Paul M; Jiang, Ying; Schmidt, Stephen D; Dinakar, Ravi; Summers-Terio, Nicole B; Ceresa, Brian P; Nixon, Ralph A; Cataldo, Anne M
2003 Aug 15;278(33):31261-31268, Journal of biological chemistry
— id: 48176, year: 2003, vol: 278, page: 31261, stat: Journal Article,

Setback for an Alzheimer's disease vaccine: Lessons learned
Mathews, Paul M; Nixon, Ralph A
2003 Jul 8;61(1):7-8, Neurology
— id: 36835, year: 2003, vol: 61, page: 7, stat: Journal Article,

The calpains in aging and aging-related diseases
Nixon, Ralph A
2003 Oct;2(4):407-418, Ageing research reviews
— id: 40066, year: 2003, vol: 2, page: 407, stat: Journal Article,

Cdk5 is a key factor in tau aggregation and tangle formation in vivo
Noble W; Olm V; Takata K; Casey E; Mary O; Meyerson J; Gaynor K; LaFrancois J; Wang L; Kondo T; Davies P; Burns M; Veeranna; Nixon R; Dickson D; Matsuoka Y; Ahlijanian M; Lau LF; Duff K
2003 May 22;38(4):555-565, Neuron
— id: 60993, year: 2003, vol: 38, page: 555, stat: Journal Article,

In vivo reduction of amyloid-beta by a mutant copper transporter
Phinney, Amie L; Drisaldi, Bettina; Schmidt, Stephen D; Lugowski, Stan; Coronado, Veronica; Liang, Yan; Horne, Patrick; Yang, Jing; Sekoulidis, Joannis; Coomaraswamy, Janaky; Chishti, M Azhar; Cox, Diane W; Mathews, Paul M; Nixon, Ralph A; Carlson, George A; St George-Hyslop, Peter; Westaway, David
2003 Nov;100(24):14193-14198, Proceedings of the National Academy of Sciences of the United States of America
— id: 159199, year: 2003, vol: 100, page: 14193, stat: Journal Article,

The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate
Rao, Mala V; Campbell, Jabbar; Yuan, Aidong; Kumar, Asok; Gotow, Takahiro; Uchiyama, Yasuo; Nixon, Ralph A
2003 Dec 8;163(5):1021-1031, Journal of cell biology
— id: 40064, year: 2003, vol: 163, page: 1021, stat: Journal Article,

Defective neurofilament transport in mouse models of amyotrophic lateral sclerosis: a review
Rao, Mala V; Nixon, Ralph A
2003 Jul;28(7):1041-1047, Neurochemical research
— id: 60267, year: 2003, vol: 28, page: 1041, stat: Journal Article,

Hypothesis for a common basis for neuroprotection in glaucoma and Alzheimer's disease: anti-apoptosis by alpha-2-adrenergic receptor activation
Tatton, William; Chen, David; Chalmers-Redman, Ruth; Wheeler, Larry; Nixon, Ralph; Tatton, Nadine
2003 Apr;48 Suppl 1:S25-S37, Survey of ophthalmology
— id: 61273, year: 2003, vol: 48 Suppl 1, page: S25, stat: Journal Article,

Neurofilament transport in vivo minimally requires hetero-oligomer formation
Yuan, Aidong; Rao, Mala V; Kumar, Asok; Julien, Jean-Pierre; Nixon, Ralph A
2003 Oct 15;23(28):9452-9458, Journal of neuroscience
— id: 39029, year: 2003, vol: 23, page: 9452, stat: Journal Article,

Study of the endosomal-lysosomal system in APPswe/PS1 transgenic mice
Zamora, E; Borchelt, DR; Jankowsky, K; Cataldo, AM; Nixon, RA; Troncoso, JC
2003 MAY ;62(5):552-552, Journal of neuropathology & experimental neurology
— id: 38570, year: 2003, vol: 62, page: 552, stat: Journal Article,

Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2
Adamec, Emil; Mohan, Panaiyur; Vonsattel, Jean P; Nixon, Ralph A
2002 Jul;104(1):92-104, Acta neuropathologica
— id: 32532, year: 2002, vol: 104, page: 92, stat: Journal Article,

P301L tauopathy: confocal immunofluorescence study of perinuclear aggregation of the mutated protein
Adamec, Emil; Murrell, Jill R; Takao, Masaki; Hobbs, Wendy; Nixon, Ralph A; Ghetti, Bernardino; Vonsattel, Jean P
2002 Aug 15;200(1-2):85-93, Journal of the neurological sciences
— id: 32531, year: 2002, vol: 200, page: 85, stat: Journal Article,

Calpain inhibitors: a treatment for Alzheimer's disease
Di Rosa, Gabriella; Odrijin, Tatjana; Nixon, Ralph A; Arancio, Ottavio
2002 Aug-Oct;19(1-2):135-141, Journal of molecular neuroscience
— id: 32533, year: 2002, vol: 19, page: 135, stat: Journal Article,

Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis
Mathews, Paul M; Guerra, Carolyn B; Jiang, Ying; Grbovic, Olivera M; Kao, Benjamin H; Schmidt, Stephen D; Dinakar, Ravi; Mercken, Marc; Hille-Rehfeld, Annette; Rohrer, Jack; Mehta, Pankaj; Cataldo, Anne M; Nixon, Ralph A
2002 Feb 15;277(7):5299-5307, Journal of biological chemistry
— id: 48164, year: 2002, vol: 277, page: 5299, stat: Journal Article,

Calpain Activity Regulates the Cell Surface Distribution of Amyloid Precursor Protein. INHIBITION OF CALPAINS ENHANCES ENDOSOMAL GENERATION OF beta -CLEAVED C-TERMINAL APP FRAGMENTS
Mathews, Paul M; Jiang, Ying; Schmidt, Stephen D; Grbovic, Olivera M; Mercken, Marc; Nixon, Ralph A
2002 Sep 27;277(39):36415-36424, Journal of biological chemistry
— id: 32534, year: 2002, vol: 277, page: 36415, stat: Journal Article,

Cell and molecular neuropathology of Alzheimer's disease
Nixon RA
Neuropsychopharmacology : the fifth generation of progress Philadelphia : Lippincott Williams & Wilkins, 2002,
— id: 4406, year: 2002, vol: , page: ?, stat: Chapter,

Neural circuitry and signaling in dementia and Alzheimer's Disease
Nixon RA
Brain circuitry and signaling in psychiatry: basic science and clinical implications Washington DC : American Psychiatric Publishing, 2002,
— id: 2655, year: 2002, vol: , page: 201, stat: Chapter,

Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density
Rao, Mala V; Engle, Linda J; Mohan, Panaiyur S; Yuan, Aidong; Qiu, Dike; Cataldo, Anne; Hassinger, Linda; Jacobsen, Stephen; Lee, Virginia M-Y; Andreadis, Athena; Julien, Jean-Pierre; Bridgman, Paul C; Nixon, Ralph A
2002 Oct 28;159(2):279-290, Journal of cell biology
— id: 32536, year: 2002, vol: 159, page: 279, stat: Journal Article,

Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport
Rao, Mala V; Garcia, Michael L; Miyazaki, Yukio; Gotow, Takahiro; Yuan, Aidong; Mattina, Salvatore; Ward, Chris M; Calcutt, Nigel A; Uchiyama, Yasuo; Nixon, Ralph A; Cleveland, Don W
2002 Aug 19;158(4):681-693, Journal of cell biology
— id: 32535, year: 2002, vol: 158, page: 681, stat: Journal Article,

Alleles at the Nicastrin locus modify presenilin 1- deficiency phenotype
Rozmahel, Richard; Mount, Howard T J; Chen, Fusheng; Nguyen, Van; Huang, Jean; Erdebil, Serap; Liauw, Jennifer; Yu, Gang; Hasegawa, Hiroshe; Gu, YongJun; Song, You-Qiang; Schmidt, Stephen D; Nixon, Ralph A; Mathews, Paul M; Bergeron, Catherine; Fraser, Paul; Westaway, David; St George-Hyslop, Peter
2002 Oct 29;99(22):14452-14457, Proceedings of the National Academy of Sciences of the United States of America
— id: 32537, year: 2002, vol: 99, page: 14452, stat: Journal Article,

Murine A beta co-deposition in transgenic mice: Analyses with species-specific antibodies and comparison of human and murine A beta 42 : A beta 40 ratios
Schmidt, S; Jiang, Y; Duff, KEK; Nixon, RA; Mathews, PM; Herzig, MC; Jucker, M; Chishti, MA; Westaway, D; Mercken, M; Staufenbiel, M
2002 Jul-Aug;23(1):920-, Neurobiology of aging
— id: 32422, year: 2002, vol: 23, page: 920, stat: Journal Article,

Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins
Yang, Dun-Sheng; Tandon, Anurag; Chen, Fusheng; Yu, Gang; Yu, Haung; Arawaka, Shigeki; Hasegawa, Hiroshi; Duthie, Monika; Schmidt, Stephen D; Ramabhadran, Triprayer V; Nixon, Ralph A; Mathews, Paul M; Gandy, Samuel E; Mount, Howard T J; St George-Hyslop, Peter; Fraser, Paul E
2002 Aug 2;277(31):28135-28142, Journal of biological chemistry
— id: 62376, year: 2002, vol: 277, page: 28135, stat: Journal Article,

Multiple-label immunocytochemistry for the evaluation of nature of cell death in experimental models of neurodegeneration
Adamec E; Yang F; Cole GM; Nixon RA
2001 Jul;7(3):193-202, Brain research protocols
— id: 25413, year: 2001, vol: 7, page: 193, stat: Journal Article,

Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders
Cataldo, A; Rebeck, GW; Ghetti, B; Hulette, C; Lippa, C; Van Broeckhovan, C; Van Duijn, C; Cras, P; Bogdanovic, N; Bird, T; Peterhoff, C; Nixon, R
2001 Nov;50(5):661-665, Annals of neurology
— id: 28208, year: 2001, vol: 50, page: 661, stat: Journal Article,

Accelerated A-beta generation in a cell model of Alzheimer's disease-related endosomal-lysomal system upregulation
Mathews PM; Guerra CB; Jiang Y; Kao BH; Dinakar R; Mehta P; Cataldo AM; Nixon RA
Alzheimer's disease: advances in etiology, pathogenesis and therapeutics Chichester: Wiley, 2001,
— id: 2653, year: 2001, vol: , page: 461, stat: Chapter,

The neuronal endosomal-lysosomal system in Alzheimer's disease
Nixon RA; Mathews PM; Cataldo AM
2001 Feb;3(1):97-107, Journal of Alzheimer's disease
— id: 32538, year: 2001, vol: 3, page: 97, stat: Journal Article,

In vivo perturbation of lysosomal function promotes neurodegeneration in the PS1m146V/APPPK67ON,M671L mouse model of Alzheimer's disease pathology
Nixon RA; Mathews PM; Cataldo AM; Mohan PS; Schmidt SD; Duff K; Berg M; Marks N; Peterhoff C; Sershen H
Alzheimer's disease: advances in etiology, pathogenesis and therapeutics Chichester: Wiley, 2001,
— id: 2654, year: 2001, vol: , page: , stat: Chapter,

Neurofilaments
Nixon RA; Rao MV
Encyclopedia of molecular medicine Chichester : Wiley, 2001,
— id: 2724, year: 2001, vol: , page: 1589, stat: Chapter,

Up-regulation of the lysosomal system in experimental models of neuronal injury: implications for Alzheimer's disease
Adamec E; Mohan PS; Cataldo AM; Vonsattel JP; Nixon RA
2000 ;100(3):663-675, Neuroscience
— id: 24717, year: 2000, vol: 100, page: 663, stat: Journal Article,

Morphological and biochemical assessment of DNA damage and apoptosis in Down syndrome and Alzheimer disease, and effect of postmortem tissue archival on TUNEL
Anderson AJ; Stoltzner S; Lai F; Su J; Nixon RA
2000 Jul-Aug;21(4):511-524, Neurobiology of aging
— id: 24725, year: 2000, vol: 21, page: 511, stat: Journal Article,

Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations
Cataldo AM; Peterhoff CM; Troncoso JC; Gomez-Isla T; Hyman BT; Nixon RA
2000 Jul;157(1):277-286, American journal of pathology
— id: 24726, year: 2000, vol: 157, page: 277, stat: Journal Article,

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
Janus C; Pearson J; McLaurin J; Mathews PM; Jiang Y; Schmidt SD; Chishti MA; Horne P; Heslin D; French J; Mount HT; Nixon RA; Mercken M; Bergeron C; Fraser PE; St George-Hyslop P; Westaway D
2000 Dec 21-28;408(6815):979-982, Nature
— id: 24772, year: 2000, vol: 408, page: 979, stat: Journal Article,

Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease
Mathews PM; Cataldo AM; Kao BH; Rudnicki AG; Qin X; Yang JL; Jiang Y; Picciano M; Hulette C; Lippa CF; Bird TD; Nochlin D; Walter J; Haass C; Levesque L; Fraser PE; Andreadis A; Nixon RA
2000 Oct;6(10):878-891, Molecular medicine
— id: 25504, year: 2000, vol: 6, page: 878, stat: Journal Article,

A "protease activation cascade" in the pathogenesis of Alzheimer's disease
Nixon RA
2000 ;924(4):117-131, Annals of the New York Academy of Sciences
— id: 25503, year: 2000, vol: 924, page: 117, stat: Journal Article,

The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review
Nixon RA; Cataldo AM; Mathews PM
2000 Oct;25(9-10):1161-1172, Neurochemical research
— id: 24724, year: 2000, vol: 25, page: 1161, stat: Journal Article,

The pathobiology of tau protein in neurodegenerative diseases
Nixon, RA; Duff, K; Matsuoka, Y
2000 APR 15 ;47(8):7S-7S, Biological psychiatry
— id: 54653, year: 2000, vol: 47, page: 7S, stat: Journal Article,

Local control of neurofilament accumulation during radial growth of myelinating axons in vivo. Selective role of site-specific phosphorylation
Sanchez I; Hassinger L; Sihag RK; Cleveland DW; Mohan P; Nixon RA
2000 Nov 27;151(5):1013-1024, Journal of cell biology
— id: 24723, year: 2000, vol: 151, page: 1013, stat: Journal Article,

DNA strand breaks in Alzheimer's disease
Adamec E; Vonsattel JP; Nixon RA
1999 Dec 4;849(1-2):67-77, Brain research
— id: 24727, year: 1999, vol: 849, page: 67, stat: Journal Article,

Isoform-specific translocation of protein kinase C following glutamate administration in primary hippocampal neurons
Buchner K; Adamec E; Beermann ML; Nixon RA
1999 Feb 5;64(2):222-235, Brain research. Molecular brain research
— id: 24729, year: 1999, vol: 64, page: 222, stat: Journal Article,

APOE genotype and gender effects on Alzheimer disease in 100 adults with Down syndrome
Lai F; Kammann E; Rebeck GW; Anderson A; Chen Y; Nixon RA
1999 Jul 22;53(2):331-336, Neurology
— id: 24728, year: 1999, vol: 53, page: 331, stat: Journal Article,

Developmental expression of wild-type and mutant presenilin-1 in hippocampal neurons from transgenic mice: evidence for novel species-specific properties of human presenilin-1
Levesque L; Annaert W; Craessaerts K; Mathews PM; Seeger M; Nixon RA; Van Leuven F; Gandy S; Westaway D; St George-Hyslop P; De Strooper B; Fraser PE
1999 Aug;5(8):542-554, Molecular medicine
— id: 24709, year: 1999, vol: 5, page: 542, stat: Journal Article,

Psychopathology
Meissner, W. W; Vaillant, George E; Nemiah, John C; Otto, Michael W; Pollack, Mark H; Jenike, Michael A; Rosenbaum, Jerrold F; Tsuang, Ming T; Faraone, Stephen V; Green, Alan I; Rothschild, Anthony J; Gunderson, Anthony G; Nixon, Ralph A; Albert, Marilyn S; Rogers, Malcolm S; Fricchione, Gregory; Reich, Peter; Grinspoon, Lester; Bakalar, James; Weiss, Roger; Herzog, David B; Becker, Anne E
The Harvard guide to psychiatry Cambridge, MA, US: Belknap Press/Harvard University Press. xiv, 856pp,
— id: 2725, year: 1999, vol: , page: 171, stat: Chapter,

Disorders of cognition
Nixon RA; Albert MS
Harvard guide to modern psychiatry Cambridge MA : Belknap Press of Harvard University Press, 1999,
— id: 4407, year: 1999, vol: , page: 328, stat: Chapter,

Calpains in the pathogenesis of Alzheimer's disease
Nixon RA; Mohan PS
Calpain: pharmacology and toxicology of calcium-dependent protease Philadelphia : Taylor & Francis, 1999,
— id: 2660, year: 1999, vol: , page: 267, stat: Chapter,

Serine-23 is a major protein kinase A phosphorylation site on the amino-terminal head domain of the middle molecular mass subunit of neurofilament proteins
Sihag RK; Jaffe H; Nixon RA; Rong X
1999 Feb;72(2):491-499, Journal of neurochemistry
— id: 24730, year: 1999, vol: 72, page: 491, stat: Journal Article,

Calpain I activation in rat hippocampal neurons in culture is NMDA receptor selective and not essential for excitotoxic cell death
Adamec E; Beermann ML; Nixon RA
1998 Feb;54(1):35-48, Brain research. Molecular brain research
— id: 25147, year: 1998, vol: 54, page: 35, stat: Journal Article,

Developmental regulation of the recovery process following glutamate-induced calcium rise in rodent primary neuronal cultures
Adamec E; Didier M; Nixon RA
1998 Jun 15;108(1-2):101-110, Brain research. Developmental brain research
— id: 25175, year: 1998, vol: 108, page: 101, stat: Journal Article,

The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex
Capell A; Grunberg J; Pesold B; Diehlmann A; Citron M; Nixon R; Beyreuther K; Selkoe DJ; Haass C
1998 Feb 6;273(6):3205-3211, Journal of biological chemistry
— id: 7520, year: 1998, vol: 273, page: 3205, stat: Journal Article,

Altered gene expression for calpain/calpastatin system in motor neuron degeneration (Mnd) mutant mouse brain and spinal cord
Li J; Nixon R; Messer A; Berman S; Bursztajn S
1998 Jan;53(1-2):174-186, Brain research. Molecular brain research
— id: 25173, year: 1998, vol: 53, page: 174, stat: Journal Article,

Dynamic behavior and organization of cytoskeletal proteins in neurons: reconciling old and new findings
Nixon RA
1998 Oct;20(10):798-807, Bioessays
— id: 7713, year: 1998, vol: 20, page: 798, stat: Journal Article,

The slow axonal transport debate
Nixon RA
1998 Mar;8(3):100-100, Trends in cell biology
— id: 25179, year: 1998, vol: 8, page: 100, stat: Journal Article,

The slow axonal transport of cytoskeletal proteins
Nixon RA
1998 Feb;10(1):87-92, Current opinion in cell biology
— id: 7712, year: 1998, vol: 10, page: 87, stat: Journal Article,

Immunocytochemistry of formalin-fixed human brain tissues: microwave irradiation of free-floating sections
Shiurba RA; Spooner ET; Ishiguro K; Takahashi M; Yoshida R; Wheelock TR; Imahori K; Cataldo AM; Nixon RA
1998 Jan;2(2):109-119, Brain research protocols
— id: 25148, year: 1998, vol: 2, page: 109, stat: Journal Article,

Neuropathology of preclinical and clinical late-onset Alzheimer's disease
Troncoso JC; Cataldo AM; Nixon RA; Barnett JL; Lee MK; Checler F; Fowler DR; Smialek JE; Crain B; Martin LJ; Kawas CH
1998 May;43(5):673-676, Annals of neurology
— id: 25174, year: 1998, vol: 43, page: 673, stat: Journal Article,

Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis
Wang KK; Posmantur R; Nadimpalli R; Nath R; Mohan P; Nixon RA; Talanian RV; Keegan M; Herzog L; Allen H
1998 Aug 15;356(2):187-196, Archives of biochemistry & biophysics. ABB
— id: 7948, year: 1998, vol: 356, page: 187, stat: Journal Article,

Acute rise in the concentration of free cytoplasmic calcium leads to dephosphorylation of the microtubule-associated protein tau
Adamec E; Mercken M; Beermann ML; Didier M; Nixon RA
1997 May 16;757(1):93-101, Brain research
— id: 25152, year: 1997, vol: 757, page: 93, stat: Journal Article,

Cellular expression and proteolytic processing of presenilin proteins is developmentally regulated during neuronal differentiation
Capell A; Saffrich R; Olivo JC; Meyn L; Walter J; Grunberg J; Mathews P; Nixon R; Dotti C; Haass C
1997 Dec;69(6):2432-2440, Journal of neurochemistry
— id: 24765, year: 1997, vol: 69, page: 2432, stat: Journal Article,

Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: neuropathologic evidence for a mechanism of increased beta-amyloidogenesis
Cataldo AM; Barnett JL; Pieroni C; Nixon RA
1997 Aug 15;17(16):6142-6151, Journal of neuroscience
— id: 25150, year: 1997, vol: 17, page: 6142, stat: Journal Article,

Calpains and calpastatin in SH-SY5Y neuroblastoma cells during retinoic acid-induced differentiation and neurite outgrowth: comparison with the human brain calpain system
Grynspan F; Griffin WB; Mohan PS; Shea TB; Nixon RA
1997 May 1;48(3):181-191, Journal of neuroscience research
— id: 24718, year: 1997, vol: 48, page: 181, stat: Journal Article,

Active site-directed antibodies identify calpain II as an early-appearing and pervasive component of neurofibrillary pathology in Alzheimer's disease
Grynspan F; Griffin WR; Cataldo A; Katayama S; Nixon RA
1997 Jul 25;763(2):145-158, Brain research
— id: 25149, year: 1997, vol: 763, page: 145, stat: Journal Article,

Triton-soluble phosphovariants of the heavy neurofilament subunit in developing and mature mouse central nervous system
Shea TB; Dahl DC; Nixon RA; Fischer I
1997 Jun 15;48(6):515-523, Journal of neuroscience research
— id: 25151, year: 1997, vol: 48, page: 515, stat: Journal Article,

Colocalization of lysosomal hydrolase and beta-amyloid in diffuse plaques of the cerebellum and striatum in Alzheimer's disease and Down's syndrome
Cataldo AM; Barnett JL; Mann DM; Nixon RA
1996 Jun;55(6):704-715, Journal of neuropathology & experimental neurology
— id: 25155, year: 1996, vol: 55, page: 704, stat: Journal Article,

Abnormalities of the endosomal-lysosomal system in Alzheimer's disease: relationship to disease pathogenesis
Cataldo AM; Hamilton DJ; Barnett JL; Paskevich PA; Nixon RA
1996 ;389(7):271-280, Advances in experimental medicine & biology
— id: 25158, year: 1996, vol: 389, page: 271, stat: Journal Article,

Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease
Cataldo AM; Hamilton DJ; Barnett JL; Paskevich PA; Nixon RA
1996 Jan;16(1):186-199, Journal of neuroscience
— id: 25159, year: 1996, vol: 16, page: 186, stat: Journal Article,

DNA strand breaks induced by sustained glutamate excitotoxicity in primary neuronal cultures
Didier M; Bursztajn S; Adamec E; Passani L; Nixon RA; Coyle JT; Wei JY; Berman SA
1996 Apr 1;16(7):2238-2250, Journal of neuroscience
— id: 25157, year: 1996, vol: 16, page: 2238, stat: Journal Article,

mu-calpain activation and calpain-mediated cytoskeletal proteolysis following traumatic brain injury
Kampfl A; Posmantur R; Nixon R; Grynspan F; Zhao X; Liu SJ; Newcomb JK; Clifton GL; Hayes RL
1996 Oct;67(4):1575-1583, Journal of neurochemistry
— id: 25172, year: 1996, vol: 67, page: 1575, stat: Journal Article,

Regional differences in gene expression for calcium activated neutral proteases (calpains) and their endogenous inhibitor calpastatin in mouse brain and spinal cord
Li J; Grynspan F; Berman S; Nixon R; Bursztajn S
1996 Jun;30(2):177-191, Journal of neurobiology
— id: 25171, year: 1996, vol: 30, page: 177, stat: Journal Article,

Oligodendroglia regulate the regional expansion of axon caliber and local accumulation of neurofilaments during development independently of myelin formation
Sanchez I; Hassinger L; Paskevich PA; Shine HD; Nixon RA
1996 Aug 15;16(16):5095-5105, Journal of neuroscience
— id: 25154, year: 1996, vol: 16, page: 5095, stat: Journal Article,

Calcium influx into human neuroblastoma cells induces ALZ-50 immunoreactivity: involvement of calpain-mediated hydrolysis of protein kinase C
Shea TB; Spencer MJ; Beermann ML; Cressman CM; Nixon RA
1996 Apr;66(4):1539-1549, Journal of neurochemistry
— id: 25156, year: 1996, vol: 66, page: 1539, stat: Journal Article,

Immunocytochemistry of tau phosphoserine 413 and tau protein kinase I in Alzheimer pathology
Shiurba RA; Ishiguro K; Takahashi M; Sato K; Spooner ET; Mercken M; Yoshida R; Wheelock TR; Yanagawa H; Imahori K; Nixon RA
1996 Oct 21;737(1-2):119-132, Brain research
— id: 25153, year: 1996, vol: 737, page: 119, stat: Journal Article,

Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system
Cataldo AM; Barnett JL; Berman SA; Li J; Quarless S; Bursztajn S; Lippa C; Nixon RA
1995 Mar;14(3):671-680, Neuron
— id: 25164, year: 1995, vol: 14, page: 671, stat: Journal Article,

Limited proteolytic processing of the mature form of cathepsin D in human and mouse brain: postmortem stability of enzyme structure and activity
Compaine A; Schein JD; Tabb JS; Mohan PS; Nixon RA
1995 Oct-Nov;27(4-5):385-396, Neurochemistry international
— id: 24719, year: 1995, vol: 27, page: 385, stat: Journal Article,

Proteolysis of protein kinase C: mM and microM calcium-requiring calpains have different abilities to generate, and degrade the free catalytic subunit, protein kinase M
Cressman CM; Mohan PS; Nixon RA; Shea TB
1995 Jul 3;367(3):223-227, FEBS letters
— id: 24720, year: 1995, vol: 367, page: 223, stat: Journal Article,

Three distinct axonal transport rates for tau, tubulin, and other microtubule-associated proteins: evidence for dynamic interactions of tau with microtubules in vivo
Mercken M; Fischer I; Kosik KS; Nixon RA
1995 Dec;15(12):8259-8267, Journal of neuroscience
— id: 25160, year: 1995, vol: 15, page: 8259, stat: Journal Article,

Differential sensitivity to proteolysis by brain calpain of adult human tau, fetal human tau and PHF-tau
Mercken M; Grynspan F; Nixon RA
1995 Jul 10;368(1):10-14, FEBS letters
— id: 25163, year: 1995, vol: 368, page: 10, stat: Journal Article,

Purification and properties of high molecular weight calpastatin from bovine brain
Mohan PS; Nixon RA
1995 Feb;64(2):859-866, Journal of neurochemistry
— id: 24721, year: 1995, vol: 64, page: 859, stat: Journal Article,

The endosoma-lysosomal system in Alzheimer disease
Nixon RA; Cataldo AM
1995 Feb;:?-?, ICOP newsletter (International Committee on Proteolysis)
— id: 25205, year: 1995, vol: , page: ?, stat: Journal Article,

The endosomal-lysosomal system of neurons: new roles
Nixon RA; Cataldo AM
1995 Nov;18(11):489-496, Trends in neurosciences
— id: 25178, year: 1995, vol: 18, page: 489, stat: Journal Article,

Elevated levels of the endosomal-lysosomal proteinase cathepsin D in cerebrospinal fluid in Alzheimer disease
Schwagerl AL; Mohan PS; Cataldo AM; Vonsattel JP; Kowall NW; Nixon RA
1995 Jan;64(1):443-446, Journal of neurochemistry
— id: 24722, year: 1995, vol: 64, page: 443, stat: Journal Article,

Aluminum treatment of intact neuroblastoma cells alters neurofilament subunit phosphorylation, solubility, and proteolysis
Shea TB; Beermann ML; Nixon RA
1995 Sep;26(1):1-14, Molecular & chemical neuropathology
— id: 25161, year: 1995, vol: 26, page: 1, stat: Journal Article,

Enhancement of neurite outgrowth following calpain inhibition is mediated by protein kinase C
Shea TB; Cressman CM; Spencer MJ; Beermann ML; Nixon RA
1995 Aug;65(2):517-527, Journal of neurochemistry
— id: 25162, year: 1995, vol: 65, page: 517, stat: Journal Article,

Degenerative changes in epinephrine tonic vasomotor neurons in Alzheimer's disease
Burke WJ; Galvin NJ; Chung HD; Stoff SA; Gillespie KN; Cataldo AM; Nixon RA
1994 Oct 24;661(1-2):35-42, Brain research
— id: 25166, year: 1994, vol: 661, page: 35, stat: Journal Article,

Lysosomal abnormalities in degenerating neurons link neuronal compromise to senile plaque development in Alzheimer disease
Cataldo AM; Hamilton DJ; Nixon RA
1994 Mar 21;640(1-2):68-80, Brain research
— id: 25169, year: 1994, vol: 640, page: 68, stat: Journal Article,

Neuronal degenerative mechanisms as clues to pathogenesis and treatment of Alzheimer's disease
Nixon RA
1994 ;15 Suppl 2(4):S61-S65, Neurobiology of aging
— id: 25177, year: 1994, vol: 15 Suppl 2, page: S61, stat: Journal Article,

Free radicals, proteolysis, and the degeneration of neurons in Alzheimer disease: how essential is the beta-amyloid link?
Nixon RA; Cataldo AM
1994 Jul-Aug;15(4):463-9; discussion 473, Neurobiology of aging
— id: 25176, year: 1994, vol: 15, page: 463, stat: Journal Article,

[32P]orthophosphate and [35S]methionine label separate pools of neurofilaments with markedly different axonal transport kinetics in mouse retinal ganglion cells in vivo
Nixon RA; Lewis SE; Mercken M; Sihag RK
1994 Nov;19(11):1445-1453, Neurochemical research
— id: 25165, year: 1994, vol: 19, page: 1445, stat: Journal Article,

Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber
Nixon RA; Paskevich PA; Sihag RK; Thayer CY
1994 Aug;126(4):1031-1046, Journal of cell biology
— id: 25168, year: 1994, vol: 126, page: 1031, stat: Journal Article,

Calcium-activated neutral proteinase (calpain) system in aging and Alzheimer's disease
Nixon RA; Saito KI; Grynspan F; Griffin WR; Katayama S; Honda T; Mohan PS; Shea TB; Beermann M
1994 Dec 15;747(3):77-91, Annals of the New York Academy of Sciences
— id: 25180, year: 1994, vol: 747, page: 77, stat: Journal Article,

Secretion of amyloid precursor protein and laminin by cultured astrocytes is influenced by culture conditions
Shea TB; Beermann ML; Honda T; Nixon RA
1994 Feb 1;37(2):197-207, Journal of neuroscience research
— id: 25170, year: 1994, vol: 37, page: 197, stat: Journal Article,

Evidence for the association of protein 4.1 immunoreactive forms with neurofibrillary tangles in Alzheimer's disease brains
Sihag RK; Wang LW; Cataldo AM; Hamlin M; Cohen CM; Nixon RA
1994 Sep 5;656(1):14-26, Brain research
— id: 25167, year: 1994, vol: 656, page: 14, stat: Journal Article,

Thyrotropin response to thyrotropin-releasing hormone in patients with dementia of the Alzheimer type
Albert M; Jenike M; Nixon R; Nobel K
1993 Feb 15;33(4):267-271, Biological psychiatry
— id: 25502, year: 1993, vol: 33, page: 267, stat: Journal Article,

Differential expression and subcellular localization of protein kinase C alpha, beta, gamma, delta, and epsilon isoforms in SH-SY5Y neuroblastoma cells: modifications during differentiation
Leli U; Shea TB; Cataldo A; Hauser G; Grynspan F; Beermann ML; Liepkalns VA; Nixon RA; Parker PJ
1993 Jan;60(1):289-298, Journal of neurochemistry
— id: 25500, year: 1993, vol: 60, page: 289, stat: Journal Article,

The regulation of neurofilament protein dynamics by phosphorylation: clues to neurofibrillary pathobiology
Nixon RA
1993 Jan;3(1):29-38, Brain pathology
— id: 25501, year: 1993, vol: 3, page: 29, stat: Journal Article,

Abnormalities of lysosomal proteolysis in neurons in Alzheimer's disease and Down's syndrome: possible relationship to b-amyloid deposition
Nixon RA; Cataldo A; Mann DMA; Paskevich PA; Hamilton DJ; Wheelock TR
Alzheimer's disease: advances in clinical and basic research New York : Wiley, 1993,
— id: 2730, year: 1993, vol: , page: 441, stat: Chapter,

The lysosomal system in neuronal cell death: a review
Nixon RA; Cataldo AM
1993 May 28;679(2):87-109, Annals of the New York Academy of Sciences
— id: 25497, year: 1993, vol: 679, page: 87, stat: Journal Article,

Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration
Saito K; Elce JS; Hamos JE; Nixon RA
1993 Apr 1;90(7):2628-2632, Proceedings of the National Academy of Sciences of the United States of America
— id: 25498, year: 1993, vol: 90, page: 2628, stat: Journal Article,

Specificity of calcium-activated neutral proteinase (CANP) inhibitors for human mu CANP and mCANP
Saito K; Nixon RA
1993 Feb;18(2):231-233, Neurochemical research
— id: 25499, year: 1993, vol: 18, page: 231, stat: Journal Article,

Proteases and protease inhibitors in Alzheimer's Disease pathogens
Banner CDB; Nixon RA
New York : NY Academy of Sciences, 1992,
— id: 639, year: 1992, vol: , page: , stat: ,

Distinct mechanisms of differentiation of SH-SY5Y neuroblastoma cells by protein kinase C activators and inhibitors
Leli U; Cataldo A; Shea TB; Nixon RA; Hauser G
1992 Apr;58(4):1191-1198, Journal of neurochemistry
— id: 25492, year: 1992, vol: 58, page: 1191, stat: Journal Article,

Slow axonal transport
Nixon RA
1992 Feb;4(1):8-14, Current opinion in cell biology
— id: 25495, year: 1992, vol: 4, page: 8, stat: Journal Article,

The lysosomal system in neurons. Involvement at multiple stages of Alzheimer's disease pathogenesis
Nixon RA; Cataldo AM; Paskevich PA; Hamilton DJ; Wheelock TR; Kanaley-Andrews L
1992 Dec 31;674(3):65-88, Annals of the New York Academy of Sciences
— id: 25488, year: 1992, vol: 674, page: 65, stat: Journal Article,

Dynamics of neuronal intermediate filaments: a developmental perspective
Nixon RA; Shea TB
1992 ;22(2):81-91, Cell motility & the cytoskeleton
— id: 25496, year: 1992, vol: 22, page: 81, stat: Journal Article,

Opposing influences of protein kinase activities on neurite outgrowth in human neuroblastoma cells: initiation by kinase A and restriction by kinase C
Shea TB; Beermann ML; Leli U; Nixon RA
1992 Nov;33(3):398-407, Journal of neuroscience research
— id: 25489, year: 1992, vol: 33, page: 398, stat: Journal Article,

Aluminum alters the electrophoretic properties of neurofilament proteins: role of phosphorylation state
Shea TB; Beermann ML; Nixon RA
1992 Feb;58(2):542-547, Journal of neurochemistry
— id: 25493, year: 1992, vol: 58, page: 542, stat: Journal Article,

Complementary effects of laminin and protease inhibitors on neurite outgrowth and maintenance
Shea TB; Beermann ML; Nixon RA
1992 ;10:53-61, Neuroscience research communications
— id: 25505, year: 1992, vol: 10, page: 53, stat: Journal Article,

Sequential effects of astroglial-derived factors on neurite outgrowth: initiation by protease inhibitors and potentiation by extracellular matrix components
Shea TB; Beermann ML; Nixon RA
1992 Feb;31(2):309-317, Journal of neuroscience research
— id: 25494, year: 1992, vol: 31, page: 309, stat: Journal Article,

Microtubule-associated protein tau is required for axonal neurite elaboration by neuroblastoma cells
Shea TB; Beermann ML; Nixon RA; Fischer I
1992 Jul;32(3):363-374, Journal of neuroscience research
— id: 25490, year: 1992, vol: 32, page: 363, stat: Journal Article,

Immunoassay and activity of calcium-activated neutral proteinase (mCANP): distribution in soluble and membrane-associated fractions in human and mouse brain
Takeuchi KH; Saito KI; Nixon RA
1992 Apr;58(4):1526-1532, Journal of neurochemistry
— id: 25491, year: 1992, vol: 58, page: 1526, stat: Journal Article,

Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease
Cataldo AM; Paskevich PA; Kominami E; Nixon RA
1991 Dec 15;88(24):10998-11002, Proceedings of the National Academy of Sciences of the United States of America
— id: 25484, year: 1991, vol: 88, page: 10998, stat: Journal Article,

Axonal transport of cytoskeletal proteins
Nixon RA
The neuronal cytoskeleton New York : Wiley-Liss, 1991,
— id: 2729, year: 1991, vol: , page: 283, stat: Chapter,

Lysosomal proteolysis in Alzheimer brain: possible roles in neuronal cell death and amyloid formation
Nixon RA; Cataldo AM
Frontiers of Alzheimer research New York : Excerpta Medica, 1991,
— id: 2732, year: 1991, vol: , page: 133, stat: Chapter,

Neurofilament phosphorylation: a new look at regulation and function
Nixon RA; Sihag RK
1991 Nov;14(11):501-506, Trends in neurosciences
— id: 25485, year: 1991, vol: 14, page: 501, stat: Journal Article,

Multiple proteases regulate neurite outgrowth in NB2a/dl neuroblastoma cells
Shea TB; Beermann ML; Nixon RA
1991 Mar;56(3):842-851, Journal of neurochemistry
— id: 25487, year: 1991, vol: 56, page: 842, stat: Journal Article,

Evidence for site- and domain-specific phosphorylation of the 145-kDa neurofilament subunit in vivo
Sihag RK; Nixon RA
Cellular regulation by protein phosphorylation Berlin : Springer-Verlag, 1991,
— id: 2731, year: 1991, vol: , page: 465, stat: Chapter,

Identification of Ser-55 as a major protein kinase A phosphorylation site on the 70-kDa subunit of neurofilaments. Early turnover during axonal transport
Sihag RK; Nixon RA
1991 Oct 5;266(28):18861-18867, Journal of biological chemistry
— id: 25486, year: 1991, vol: 266, page: 18861, stat: Journal Article,

Neuroleptic-associated autoantibodies. A prevalence study
Canoso RT; de Oliveira RM; Nixon RA
1990 Apr 15;27(8):863-870, Biological psychiatry
— id: 25480, year: 1990, vol: 27, page: 863, stat: Journal Article,

Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brain
Cataldo AM; Nixon RA
1990 May;87(10):3861-3865, Proceedings of the National Academy of Sciences of the United States of America
— id: 25478, year: 1990, vol: 87, page: 3861, stat: Journal Article,

Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: evidence for a neuronal origin
Cataldo AM; Thayer CY; Bird ED; Wheelock TR; Nixon RA
1990 Apr 16;513(2):181-192, Brain research
— id: 25479, year: 1990, vol: 513, page: 181, stat: Journal Article,

Aluminum inhibits calpain-mediated proteolysis and induces human neurofilament proteins to form protease-resistant high molecular weight complexes
Nixon RA; Clarke JF; Logvinenko KB; Tan MK; Hoult M; Grynspan F
1990 Dec;55(6):1950-1959, Journal of neurochemistry
— id: 25476, year: 1990, vol: 55, page: 1950, stat: Journal Article,

Synthesis, axonal transport, and turnover of the high molecular weight microtubule-associated protein MAP 1A in mouse retinal ganglion cells: tubulin and MAP 1A display distinct transport kinetics
Nixon RA; Fischer I; Lewis SE
1990 Feb;110(2):437-448, Journal of cell biology
— id: 25483, year: 1990, vol: 110, page: 437, stat: Journal Article,

Post-translational modification of alpha-tubulin by acetylation and detyrosination in NB2a/d1 neuroblastoma cells
Shea TB; Beermann ML; Nixon RA
1990 Feb 1;51(2):195-204, Brain research. Developmental brain research
— id: 25482, year: 1990, vol: 51, page: 195, stat: Journal Article,

Dynamics of phosphorylation and assembly of the high molecular weight neurofilament subunit in NB2a/d1 neuroblastoma
Shea TB; Sihag RK; Nixon RA
1990 Nov;55(5):1784-1792, Journal of neurochemistry
— id: 25477, year: 1990, vol: 55, page: 1784, stat: Journal Article,

Phosphorylation of the amino-terminal head domain of the middle molecular mass 145-kDa subunit of neurofilaments. Evidence for regulation by second messenger-dependent protein kinases
Sihag RK; Nixon RA
1990 Mar 5;265(7):4166-4171, Journal of biological chemistry
— id: 25481, year: 1990, vol: 265, page: 4166, stat: Journal Article,

Fluoxetine versus trazodone in depressed geriatric patients
Falk WE; Rosenbaum JF; Otto MW; Zusky PM; Weilburg JB; Nixon RA
1989 Oct-Dec;2(4):208-214, Journal of geriatric psychiatry & neurology
— id: 25471, year: 1989, vol: 2, page: 208, stat: Journal Article,

Calcium-activated neutral proteinases as regulators of cellular function. Implications for Alzheimer's disease pathogenesis
Nixon RA
1989 ;568(1):198-208, Annals of the New York Academy of Sciences
— id: 25475, year: 1989, vol: 568, page: 198, stat: Journal Article,

Early posttranslational modifications of the three neurofilament subunits in mouse retinal ganglion cells: neuronal sites and time course in relation to subunit polymerization and axonal transport
Nixon RA; Lewis SE; Dahl D; Marotta CA; Drager UC
1989 Mar;5(2):93-108, Brain research. Molecular brain research
— id: 25473, year: 1989, vol: 5, page: 93, stat: Journal Article,

Appearance and localization of phosphorylated variants of the high molecular weight neurofilament protein in NB2a/d1 cytoskeletons during differentiation
Shea TB; Beermann ML; Nixon RA
1989 Nov 1;50(1):142-146, Brain research. Developmental brain research
— id: 25470, year: 1989, vol: 50, page: 142, stat: Journal Article,

Aluminum salts induce the accumulation of neurofilaments in perikarya of NB2a/dl neuroblastoma
Shea TB; Clarke JF; Wheelock TR; Paskevich PA; Nixon RA
1989 Jul 17;492(1-2):53-64, Brain research
— id: 25472, year: 1989, vol: 492, page: 53, stat: Journal Article,

In vivo phosphorylation of distinct domains of the 70-kilodalton neurofilament subunit involves different protein kinases
Sihag RK; Nixon RA
1989 Jan 5;264(1):457-464, Journal of biological chemistry
— id: 25474, year: 1989, vol: 264, page: 457, stat: Journal Article,

Multiple phosphorylated variants of the high molecular mass subunit of neurofilaments in axons of retinal cell neurons: characterization and evidence for their differential association with stationary and moving neurofilaments
Lewis SE; Nixon RA
1988 Dec;107(6 Pt 2):2689-2701, Journal of cell biology
— id: 25464, year: 1988, vol: 107, page: 2689, stat: Journal Article,

Possible synergism between fluoxetine and lithium in refractory depression
Pope HG Jr; McElroy SL; Nixon RA
1988 Oct;145(10):1292-1294, American journal of psychiatry
— id: 25466, year: 1988, vol: 145, page: 1292, stat: Journal Article,

Soluble, phosphorylated forms of the high molecular weight neurofilament protein in perikarya of cultured neuronal cells
Shea TB; Majocha RE; Marotta CA; Nixon RA
1988 Oct 17;92(3):291-297, Neuroscience letters
— id: 25465, year: 1988, vol: 92, page: 291, stat: Journal Article,

Differential distribution of vimentin and neurofilament protein immunoreactivity in NB2a/d1 neuroblastoma cells following neurite retraction distinguishes two separate intermediate filament systems
Shea TB; Nixon RA
1988 Jun 1;469(1-2):298-302, Brain research
— id: 25469, year: 1988, vol: 469, page: 298, stat: Journal Article,

Neurofilament triplet proteins of NB2a/d1 neuroblastoma: posttranslational modification and incorporation into the cytoskeleton during differentiation
Shea TB; Sihag RK; Nixon RA
1988 Sep 1;471(1):97-109, Brain research
— id: 25467, year: 1988, vol: 471, page: 97, stat: Journal Article,

Phosphorylation of neurofilament proteins by protein kinase C
Sihag RK; Jeng AY; Nixon RA
1988 Jun 6;233(1):181-185, FEBS letters
— id: 25468, year: 1988, vol: 233, page: 181, stat: Journal Article,

The axonal transport of cytoskeletal proteins: a reappraisal
Nixon RA
Axonal transport New York : Liss, 1987,
— id: 2726, year: 1987, vol: , page: 175, stat: Chapter,

Phosphorylation and dephosphorylation of neurofilament proteins in retinal ganglion cell neurons in vivo
Nixon RA; Lewis SE
1987 ;221(4):167-186, Advances in experimental medicine & biology
— id: 25463, year: 1987, vol: 221, page: 167, stat: Journal Article,

Posttranslational modification of neurofilament proteins by phosphate during axoplasmic transport in retinal ganglion cell neurons
Nixon RA; Lewis SE; Marotta CA
1987 Apr;7(4):1145-1158, Journal of neuroscience
— id: 25462, year: 1987, vol: 7, page: 1145, stat: Journal Article,

A versatile transition metal salt reaction for a wide range of common biochemical reagents: an instantaneous and quantifiable color test
Fleming N; Nixon RA
1986 May 1;154(2):691-701, Analytical biochemistry
— id: 25457, year: 1986, vol: 154, page: 691, stat: Journal Article,

Fodrin degradation by calcium-activated neutral proteinase (CANP) in retinal ganglion cell neurons and optic glia: preferential localization of CANP activities in neurons
Nixon RA
1986 May;6(5):1264-1271, Journal of neuroscience
— id: 25458, year: 1986, vol: 6, page: 1264, stat: Journal Article,

Differential turnover of phosphate groups on neurofilament subunits in mammalian neurons in vivo
Nixon RA; Lewis SE
1986 Dec 15;261(35):16298-16301, Journal of biological chemistry
— id: 25454, year: 1986, vol: 261, page: 16298, stat: Journal Article,

Multiple fates of newly synthesized neurofilament proteins: evidence for a stationary neurofilament network distributed nonuniformly along axons of retinal ganglion cell neurons
Nixon RA; Logvinenko KB
1986 Feb;102(2):647-659, Journal of cell biology
— id: 25460, year: 1986, vol: 102, page: 647, stat: Journal Article,

Multiple calcium-activated neutral proteinases (CANP) in mouse retinal ganglion cell neurons: specificities for endogenous neuronal substrates and comparison to purified brain CANP
Nixon RA; Quackenbush R; Vitto A
1986 May;6(5):1252-1263, Journal of neuroscience
— id: 25459, year: 1986, vol: 6, page: 1252, stat: Journal Article,

The epidemiology of ipecac abuse
Pope HG Jr; Hudson JI; Nixon RA; Herridge PL
1986 Jan 23;314(4):245-246, New England journal of medicine
— id: 25461, year: 1986, vol: 314, page: 245, stat: Journal Article,

Calcium-activated neutral proteinase of human brain: subunit structure and enzymatic properties of multiple molecular forms
Vitto A; Nixon RA
1986 Oct;47(4):1039-1051, Journal of neurochemistry
— id: 25456, year: 1986, vol: 47, page: 1039, stat: Journal Article,

Cerebrospinal fluid levels of angiotensin-converting enzyme, acetylcholinesterase, and dopamine metabolites in dementia associated with Alzheimer's disease and Parkinson's disease: a correlative study
Zubenko GS; Marquis JK; Volicer L; Direnfeld LK; Langlais PJ; Nixon RA
1986 Dec;21(14):1365-1381, Biological psychiatry
— id: 25455, year: 1986, vol: 21, page: 1365, stat: Journal Article,

Evidence for a stationary nonuniform network of neurofilaments along retinal ganglion cell axons
Nixon RA; Logvinenko KB; Fisher WH
1985 ;455:797-800, Annals of the New York Academy of Sciences
— id: 25506, year: 1985, vol: 455, page: 797, stat: Journal Article,

Captopril and teprotide as discriminators of angiotensin-converting enzyme activity in brain tissue
Zubenko GS; Nixon RA
1985 Sep 16;60(1):33-37, Neuroscience letters
— id: 25452, year: 1985, vol: 60, page: 33, stat: Journal Article,

Cerebrospinal fluid levels of angiotensin-converting enzyme in Alzheimer's disease, Parkinson's disease and progressive supranuclear palsy
Zubenko GS; Volicer L; Direnfeld LK; Freeman M; Langlais PJ; Nixon RA
1985 Mar 4;328(2):215-221, Brain research
— id: 25453, year: 1985, vol: 328, page: 215, stat: Journal Article,

Degradation of neurofilament proteins by purified human brain cathepsin D
Nixon RA; Marotta CA
1984 Aug;43(2):507-516, Journal of neurochemistry
— id: 25449, year: 1984, vol: 43, page: 507, stat: Journal Article,

Proteases of human brain
Pope A; Nixon RA
1984 Mar;9(3):291-323, Neurochemical research
— id: 25450, year: 1984, vol: 9, page: 291, stat: Journal Article,

Mood-elevating effect of captopril in depressed patients
Zubenko GS; Nixon RA
1984 Jan;141(1):110-111, American journal of psychiatry
— id: 25451, year: 1984, vol: 141, page: 110, stat: Journal Article,

Proteolysis of neurofilaments
Nixon RA
Neurofilaments Minneapolis : Univ of Minnesota Press, 1983,
— id: 2728, year: 1983, vol: , page: 117, stat: Chapter,

Limited proteolytic modification of a neurofilament protein involves a proteinase activated by endogenous levels of calcium
Nixon RA; Brown BA; Marotta CA
1983 Sep 26;275(2):384-388, Brain research
— id: 25448, year: 1983, vol: 275, page: 384, stat: Journal Article,

Water intoxication, demeclocycline, and antidiuretic hormone -- reply
Nixon RA; Chin WW
1983 Jun;140(6):815-815, American journal of psychiatry
— id: 72840, year: 1983, vol: 140, page: 815, stat: Journal Article,

Posttranslational processing of alpha-tubulin during axoplasmic transport in CNS axons
Brown BA; Nixon RA; Marotta CA
1982 Jul;94(1):159-164, Journal of cell biology
— id: 25444, year: 1982, vol: 94, page: 159, stat: Journal Article,

Increased axonal proteolysis in myelin-deficient mutant mice
Nixon RA
1982 Feb 19;215(4535):999-1001, Science
— id: 25447, year: 1982, vol: 215, page: 999, stat: Journal Article,

Posttranslational modification of a neurofilament protein during axoplasmic transport: implications for regional specialization of CNS axons
Nixon RA; Brown BA; Marotta CA
1982 Jul;94(1):150-158, Journal of cell biology
— id: 25445, year: 1982, vol: 94, page: 150, stat: Journal Article,

Demeclocycline in the prophylaxis of self-induced water intoxication
Nixon RA; Rothman JS; Chin W
1982 Jun;139(6):828-830, American journal of psychiatry
— id: 25446, year: 1982, vol: 139, page: 828, stat: Journal Article,

Characterization and comparison of neurofilament proteins from rat and mouse CNS
Brown BA; Nixon RA; Strocchi P; Marotta CA
1981 Jan;36(1):143-153, Journal of neurochemistry
— id: 25443, year: 1981, vol: 36, page: 143, stat: Journal Article,

Protease activities in normal and schizophrenic human prefrontal cortex and white matter
Pope A; Amelotte JA; Belfer H; Nixon RA
1981 Oct;6(10):1043-1052, Neurochemical research
— id: 25442, year: 1981, vol: 6, page: 1043, stat: Journal Article,

Protein degradation in the mouse visual system. I. Degradation of axonally transported and retinal proteins
Nixon RA
1980 Oct 27;200(1):69-83, Brain research
— id: 25441, year: 1980, vol: 200, page: 69, stat: Journal Article,

Genetic control of retinal ganglion cell projections
LaVail JH; Nixon RA; Sidman RL
1978 Dec 1;182(3):399-421, Journal of comparative neurology
— id: 25439, year: 1978, vol: 182, page: 399, stat: Journal Article,

Quinine sulfate for pain in the Guillain-Barre syndrome
Nixon RA
1978 Oct;4(4):386-387, Annals of neurology
— id: 25440, year: 1978, vol: 4, page: 386, stat: Journal Article,

Uptake and metabolism of intraventricularly administered piperidine and its effects on sleep and wakefulness in the rat
Nixon RA; Karnovsky ML
1977 Oct 14;134(3):501-511, Brain research
— id: 25438, year: 1977, vol: 134, page: 501, stat: Journal Article,

Neurotoxicity of a non-metabolizable amino acid, 1 -aminocyclopentane-1-carboxylic acid (ACPC): ACPC transport mechanisms in tissues
Nixon RA
1976 Mar 15;25(6):726-729, Biochemical pharmacology
— id: 25437, year: 1976, vol: 25, page: 726, stat: Journal Article,

Neurotoxicity of a non-metabolizable amino acid, 1-aminocyclopentane-1-carboxylic acid: regional protein levels and lipid composition of nervous tissue
Nixon RA
1976 Jul;27(1):237-244, Journal of neurochemistry
— id: 25436, year: 1976, vol: 27, page: 237, stat: Journal Article,

Neurotoxicity of a non-metabolizable amino acid, 1-aminocyclopentane-1-carboxylic acid: antagonism by amino acids in cultures of cerebellum
Nixon RA; Suva M; Wolf MK
1976 Jul;27(1):245-251, Journal of neurochemistry
— id: 25435, year: 1976, vol: 27, page: 245, stat: Journal Article,

Studies on the neurotoxicity of a non-metabolized amino acid, 1-aminocyclopentane-1-carboxylic acid
Nixon, Ralth Angus
[S.l. : s.n], 1974,
— id: 1334, year: 1974, vol: , page: , stat: ,

Volatile amines in mouse brain: a radioassay with picogram sensitivity
Nixon R
1972 Aug;48(2):460-470, Analytical biochemistry
— id: 25434, year: 1972, vol: 48, page: 460, stat: Journal Article,

Comparison of cerebral sphingolipid metabolism in vivo in "quaking" and normal mice
Nixon, R; Kanfer, J N
1971 Jan 22;10(2):71-79, Life sciences
— id: 25433, year: 1971, vol: 10, page: 71, stat: Journal Article,

Interaction of ribosomes and the cell envelope of Escherichia coli mediated by lysozyme
Patterson D; Weinstein M; Nixon R; Gillespie D
1970 Feb;101(2):584-591, Journal of bacteriology
— id: 25432, year: 1970, vol: 101, page: 584, stat: Journal Article,

Screening of Escherichia coli temperature-sensitive mutants by pretreatment with glucose starvation
Boyd D; Nixon R; Gillespie S; Gillespie D
1968 Mar;95(3):1040-1050, Journal of bacteriology
— id: 25431, year: 1968, vol: 95, page: 1040, stat: Journal Article,