Biosketch / Results /

Souhel Najjar, M.D.

Clinical Associate Professor;
Department of Neurology (Epilepsy Center Div)

Clinical Addresses

NEW YORK, NY 10016
Hours: Mon. 9 - 5; Tue. 9 - 5; Wed. 9 - 5; Thu. 9 - 5; Fri. 9 - 3
Handicap Access: yes
Phone: 646-558-0807
Fax: 646-385-7166

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Medical Specialties

Pediatric Neurology, Neurology

Medical Expertise

Seizure Disorders (Epilepsy), Headaches (Migraines)

Clinical Responsibilities

Dr. Najjar is an associate professor of neurology at the NYU Medical Center. He joined the Comprehensive Epilepsy Center in 1998 and serves as the director of the EEG Laboratory. Dr. Najjar is also the director of the Neuroscience Center at the Staten Island University Hospital. Dr. Najjar graduated from the Damascus Medical School in Damascus, Syria in 1983, and did his residency at the Albany medical College in Albany, NY, specializing in pathology and neurology. He also completed neuropathology and epilepsy fellowships at NYU Medical Center. His research interests include histological analysis and investigation of neuroinflammatory factors in surgically resected epileptic tissue.


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Board Certification

1993 — Ab Psychiatry & Neurology - Neurology


1983 — Damascus University, Medical Education
1985-1988 — Albany Medical Center Hospital, Residency Training
1988-1989 — New York Downtown Hospital, Internship
1989-1992 — Albany Medical Center Hospital, Residency Training
1992-1994 — NYU Medical Center (Neuropathology), Clinical Fellowships

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All data from NYU Health Sciences Library Faculty Bibliography — -


Major depressive disorder and neurovascular unit dysfunction with blood-brain barrier hyperpermeability: A critical analysis of human and experimental data
Najjar, S; Pearlman, D M; Devinsky, O; Najjar, A; Zagzag, D
2014 February 2014;20(1):18-19, Neurology, psychiatry, & brain research
— id: 853742, year: 2014, vol: 20, page: 18, stat: Journal Article,

Neuroinflammation and white matter pathology in schizophrenia: systematic review
Najjar, Souhel; Pearlman, Daniel M
2014 Jun;:50-50, Schizophrenia research
— id: 1050662, year: 2014, vol: , page: 50, stat: Journal Article,

Blood Levels of S-100 Calcium-Binding Protein B, High-Sensitivity C-Reactive Protein, and Interleukin-6 for Changes in Depressive Symptom Severity after Coronary Artery Bypass Grafting: Prospective Cohort Nested within a Randomized, Controlled Trial
Pearlman, Daniel M; Brown, Jeremiah R; MacKenzie, Todd A; Hernandez, Felix Jr; Najjar, Souhel
2014 ;9(10):e111110-e111110 e111110, PLoS one
— id: 1315382, year: 2014, vol: 9, page: e111110, stat: Journal Article,

Meta-analysis of the association between N-methyl-d-aspartate receptor antibodies and schizophrenia, schizoaffective disorder, bipolar disorder, and major depressive disorder
Pearlman, Daniel M; Najjar, Souhel
2014 May;:2173-2175, Schizophrenia research
— id: 1030552, year: 2014, vol: , page: 2173, stat: Journal Article,

Neuroinflammation Versus Decreased Zif268 mRNA Expression as Causal Mediators of Decreased GAD67 mRNA Expression Within Dorsolateral Prefrontal Cortex in Schizophrenia
Pearlman, Daniel M; Najjar, Souhel
2014 Oct;171(10):1117-1118, American journal of psychiatry
— id: 1283002, year: 2014, vol: 171, page: 1117, stat: Journal Article,

Anti-basal ganglia antibodies in primary obsessive-compulsive disorder: systematic review and meta-analysis
Pearlman, Daniel M; Vora, Haily S; Marquis, Brian G; Najjar, Souhel; Dudley, Lauren A
2014 Jul;205(1):8-16, British journal of psychiatry
— id: 1065792, year: 2014, vol: 205, page: 8, stat: Journal Article,

Epilepsy associated with systemic autoimmune disorders
Devinsky, Orrin; Schein, Adam; Najjar, Souhel
2013 Mar;13(2):62-68, Epilepsy currents
— id: 335662, year: 2013, vol: 13, page: 62, stat: Journal Article,

Glia and epilepsy: excitability and inflammation
Devinsky, Orrin; Vezzani, Annamaria; Najjar, Souhel; De Lanerolle, Nihal C; Rogawski, Michael A
2013 Jan;:7779-7783, Trends in neurosciences
— id: 214212, year: 2013, vol: , page: 7779, stat: Journal Article,

Evidence of increased neuroinflammation in human tuberous sclerosis complex potential implications for neurological dysfunction
Dilsiz, P; Ruppe, V; Weiner, H; Shoshkes, Reiss C; Najjar, S; French, J; Devinsky, O; Talos, D M
2013 March-April 2013;13:347-347, Epilepsy currents
— id: 612732, year: 2013, vol: 13, page: 347, stat: Journal Article,

Neuroinflammation and psychiatric illness
Najjar, Souhel; Pearlman, Daniel M; Alper, Kenneth; Najjar, Amanda; Devinsky, Orrin
2013 ;10:43-43, Journal of neuroinflammation
— id: 301282, year: 2013, vol: 10, page: 43, stat: Journal Article,

Neurovascular unit dysfunction with blood-brain barrier hyperpermeability contributes to major depressive disorder: a review of clinical and experimental evidence
Najjar, Souhel; Pearlman, Daniel M; Devinsky, Orrin; Najjar, Amanda; Zagzag, David
2013 ;10(1):142-142, Journal of neuroinflammation
— id: 681072, year: 2013, vol: 10, page: 142, stat: Journal Article,

Brain Biopsy Findings Link Major Depressive Disorder to Neuroinflammation, Oxidative Stress, and Neurovascular Dysfunction: A Case Report
Najjar, Souhel; Pearlman, Daniel M; Hirsch, Scott; Friedman, Kent; Strange, John; Reidy, Jason; Khoukaz, Maya; Ferrell, Richard B; Devinsky, Orrin; Najjar, Amanda; Zagzag, David
2013 Sep;:611-612, Biological psychiatry
— id: 688022, year: 2013, vol: , page: 611, stat: Journal Article,

Neuropsychiatric Autoimmune Encephalitis without VGKC-Complex, NMDAR, and GAD Autoantibodies: Case Report and Literature Review
Najjar, Souhel; Pearlman, Daniel; Devinsky, Orrin; Najjar, Amanda; Nadkarni, Siddhartha; Butler, Tracy; Zagzag, David
2013 Mar;26(1):36-49, Cognitive & behavioral neurology
— id: 271382, year: 2013, vol: 26, page: 36, stat: Journal Article,

Glutamic Acid decarboxylase autoantibody syndrome presenting as schizophrenia
Najjar, Souhel; Pearlman, Daniel; Zagzag, David; Golfinos, John; Devinsky, Orrin
2012 Mar;18(2):88-91, Neurologist
— id: 158282, year: 2012, vol: 18, page: 88, stat: Journal Article,

Classifying seizures and epilepsies: limits of science and semantics
Devinsky, Orrin; Najjar, Souhel
2011 Sep;11(5):141-142, Epilepsy currents
— id: 139494, year: 2011, vol: 11, page: 141, stat: Journal Article,

Extralimbic autoimmune encephalitis associated with glutamic acid decarboxylase antibodies: An underdiagnosed entity?
Najjar S; Pearlman D; Najjar A; Ghiasian V; Zagzag D; Devinsky O
2011 Jul;21(3):306-313, Epilepsy & behavior
— id: 134074, year: 2011, vol: 21, page: 306, stat: Journal Article,

Refractory epilepsy associated with microglial activation
Najjar, Souhel; Pearlman, Daniel; Miller, Douglas C; Devinsky, Orrin
2011 Sep;17(5):249-254, Neurologist
— id: 137008, year: 2011, vol: 17, page: 249, stat: Journal Article,

Spontaneously resolving seronegative autoimmune limbic encephalitis
Najjar, Souhel; Pearlman, Daniel; Zagzag, David; Devinsky, Orrin
2011 Jun;24(2):99-105, Cognitive & behavioral neurology
— id: 134726, year: 2011, vol: 24, page: 99, stat: Journal Article,

Phenotypic Heterogeneity and Type-1/2 PrPSc Co-Occurrence in Creutzfeldt-Jakob Disease Associated With a new Mutation of PRNP
Puoti, G; Nigro, M; Chen, S; Cali, I; Cracco, L; Blevins, J; Najjar, S; Hamilton, RL; Gambetti, P
2010 MAY ;69(5):534-534, Journal of neuropathology & experimental neurology
— id: 111904, year: 2010, vol: 69, page: 534, stat: Journal Article,

Immunology and epilepsy
Najjar, Souhel; Bernbaum, Melissa; Lai, George; Devinsky, Orrin
2008 Summer;5(3):109-116, Reviews in neurological diseases
— id: 91975, year: 2008, vol: 5, page: 109, stat: Journal Article,

Pediatric language mapping: sensitivity of neurostimulation and Wada testing in epilepsy surgery
Schevon, Catherine A; Carlson, Chad; Zaroff, Charles M; Weiner, Howard J; Doyle, Werner K; Miles, Daniel; Lajoie, Josiane; Kuzniecky, Ruben; Pacia, Steven; Vazquez, Blanca; Luciano, Daniel; Najjar, Souhel; Devinsky, Orrin
2007 Mar;48(3):539-545, Epilepsia
— id: 71610, year: 2007, vol: 48, page: 539, stat: Journal Article,

Race/ethnicity, sex, and socioeconomic status as predictors of outcome after surgery for temporal lobe epilepsy
Burneo, Jorge G; Black, Lorie; Martin, Roy; Devinsky, Orrin; Pacia, Steve; Faught, Edward; Vasquez, Blanca; Knowlton, Robert C; Luciano, Daniel; Doyle, Werner; Najjar, Sohuel; Kuzniecky, Ruben I
2006 Aug;63(8):1106-1110, Archives of neurology
— id: 69045, year: 2006, vol: 63, page: 1106, stat: Journal Article,

Adult-onset epilepsy in focal cortical dysplasia of Taylor type
Siegel, A M; Cascino, G D; Elger, C E; Devinsky, O; Laff, R; Najjar, S; Sperling, M R; LoRusso, G; Cossu, M; Urbach, H; Aronica, E; Meyer, F B; Scheithauer, B W; Dubeau, F; Andermann, F
2005 May 24;64(10):1771-1774, Neurology
— id: 139500, year: 2005, vol: 64, page: 1771, stat: Journal Article,

Clinical features of patients with unilateral mesial temporal sclerosis (MTS) with persistent seizures following antero-mesial temporal resection
Yousef, TA; Pacia, SV; Barr, W; Cohen, E; Doyle, W; Devinsky, O; Luciano, D; Vazquez, B; Miles, D; Najjar, S; Kuzniecky, R
2004 AUG-SEP ;45(3):88-88, Epilepsia
— id: 49017, year: 2004, vol: 45, page: 88, stat: Journal Article,

Epilepsy surgery in tuberous sclerosis: multistage procedures with bilateral or multilobar foci
Romanelli, Pantaleo; Najjar, Souhel; Weiner, Howard L; Devinsky, Orrin
2002 Sep;17(9):689-692, Journal of child neurology
— id: 34403, year: 2002, vol: 17, page: 689, stat: Journal Article,

Bilateral resective epilepsy surgery in a child with tuberous sclerosis: case report
Romanelli P; Weiner HL; Najjar S; Devinsky O
2001 Sep;49(3):732-4; discussion 735, Neurosurgery
— id: 33905, year: 2001, vol: 49, page: 732, stat: Journal Article,

Excellent outcome of surgical treatment for refractory epilepsy associated with extratemporal MRI identified disorders of cortical development
Bernadette, E; Doyle, W; Devinsky, O; Pacia, S; Vazquez, B; Luciano, D; Najjar, S; Mesad, S; Zupanc, M; Silverberg, A; Rivera, E
1999 OCT ;40(9):217-217, Epilepsia
— id: 53861, year: 1999, vol: 40, page: 217, stat: Journal Article,

Evidence against the existence of a temporal lobe epilepsy personality syndrome
Devinsky O; Najjar S
1999 ;53(5 Suppl 2):S13-S25, Neurology
— id: 11960, year: 1999, vol: 53, page: S13, stat: Journal Article,

Neuropathology of AIDS in surgical biopsy specimens
Miller DC; Najjar S; Budzilovich GN
1994 Jan;5(1):57-70, Neurosurgery clinics of North America
— id: 13021, year: 1994, vol: 5, page: 57, stat: Journal Article,