Moon-Shong Tang, Ph.D.

Effect of CpG methylation at different sequence context on acrolein- and BPDE-DNA binding and mutagenesis
Wang, Hsiang-Tsui; Weng, Mao-Wen; Chen, Wen-Chi; Yobin, Michael; Pan, Jishen; Chung, Fung-Lung; Wu, Xue-Ru; Rom, William; Tang, Moon-Shong
2013 Jan;34(1):220-227, Carcinogenesis
— id: 216532, year: 2013, vol: 34, page: 220, stat: Journal Article,

Chromium (VI) induces both bulky DNA adducts and oxidative DNA damage at adenines and guanines in the p53 gene of human lung cells
Arakawa, Hirohumi; Weng, Mao-Wen; Chen, Wen-Chi; Tang, Moon-Shong
2012 Oct;33(10):1993-2000, Carcinogenesis
— id: 179079, year: 2012, vol: 33, page: 1993, stat: Journal Article,

Detection of acrolein-derived cyclic DNA adducts in human cells by monoclonal antibodies
Pan, Jishen; Awoyemi, Bisola; Xuan, Zhuoli; Vohra, Priya; Wang, Hsiang-Tsui; Dyba, Marcin; Greenspan, Emily; Fu, Ying; Creswell, Karen; Zhang, Lihua; Berry, Deborah; Tang, Moon-Shong; Chung, Fung-Lung
2012 Dec;25(12):2788-2795, Chemical research in toxicology
— id: 209662, year: 2012, vol: 25, page: 2788, stat: Journal Article,

Effect of carcinogenic acrolein on DNA repair and mutagenic susceptibility
Wang HT; Hu Y; Tong D; Huang J; Gu L; Wu XR; Chung FL; Li GM; Tang MS
2012 Jan 24;:12379-12386 #, Journal of biological chemistry
— id: 150550, year: 2012, vol: , page: 12379, stat: Journal Article,

Chromium induces chromosomal instability, which is partly due to deregulation of BubR1 and Emi1, two APC/C inhibitors
Hu, Liyan; Liu, Xin; Chervona, Yana; Yang, Feikun; Tang, Moon-Shong; Darzynkiewicz, Zbigniew; Dai, Wei
2011 Jul 15;10(14):2373-2379, Cell cycle
— id: 135558, year: 2011, vol: 10, page: 2373, stat: Journal Article,

Acrolein induced DNA damage, mutagenicity and effect on DNA repair
Tang, Moon-Shong; Wang, Hsiang-Tsui; Hu, Yu; Chen, Wei-Sheng; Akao, Makoto; Feng, Zhaohui; Hu, Wenwei
2011 Sep;55(9):1291-1300, Molecular nutrition & food research
— id: 137067, year: 2011, vol: 55, page: 1291, stat: Journal Article,

Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells
Bhatnagar, N; Li, X; Padi, S K R; Zhang, Q; Tang, M-S; Guo, B
2010 ;1:e105-e105, Cell death & disease
— id: 135623, year: 2010, vol: 1, page: e105, stat: Journal Article,

Ultraviolet A light: potential underlying causes of melanoma
Tang, Moon-Shong
2010 Oct;6(10):1523-1526, Future Oncology
— id: 114194, year: 2010, vol: 6, page: 1523, stat: Journal Article,

Melanocytes are deficient in repair of oxidative DNA damage and UV-induced photoproducts
Wang, Hsiang-Tsui; Choi, Bongkun; Tang, Moon-shong
2010 Jul 6;107(27):12180-12185, Proceedings of the National Academy of Sciences of the United States of America
— id: 110876, year: 2010, vol: 107, page: 12180, stat: Journal Article,

Repair of mitomycin C mono- and interstrand cross-linked DNA adducts by UvrABC: a new model
Weng, Mao-Wen; Zheng, Yi; Jasti, Vijay P; Champeil, Elise; Tomasz, Maria; Wang, Yinsheng; Basu, Ashis K; Tang, Moon-Shong
2010 Nov 1;38(20):6976-6984, Nucleic acids research
— id: 114506, year: 2010, vol: 38, page: 6976, stat: Journal Article,

DNA wrapping is required for DNA damage recognition in the Escherichia coli DNA nucleotide excision repair pathway
Wang, Hailin; Lu, Meiling; Tang, Moon-shong; Van Houten, Bennett; Ross, J B Alexander; Weinfeld, Michael; Le, X Chris
2009 Aug 4;106(31):12849-12854, Proceedings of the National Academy of Sciences of the United States of America
— id: 133700, year: 2009, vol: 106, page: 12849, stat: Journal Article,

Mutagenicity and Sequence Specificity of Acrolein-DNA Adducts
Wang, Hsiang-Tsui; Zhang, Siyi; Hu, Yu; Tang, Moon-Shong
2009 Mar 16;22(3):511-517, Chemical research in toxicology
— id: 98293, year: 2009, vol: 22, page: 511, stat: Journal Article,

Recognition and incision of Cr(III) ligand-conjugated DNA adducts by the nucleotide excision repair proteins UvrABC: importance of the Cr(III)-purine moiety in the enzymatic reaction
Arakawa, Hirohumi; Tang, Moon-Shong
2008 Jun;21(6):1284-1289, Chemical research in toxicology
— id: 93303, year: 2008, vol: 21, page: 1284, stat: Journal Article,

PAH-DNA adducts in a Chinese population: relationship to PAH exposure, smoking and polymorphisms of metabolic and DNA repair genes
Hu, Yu; Li, Gang; Xue, Xiaonan; Zhou, Zongcan; Li, Xiaomei; Fu, Juanling; Cohen, Beverly; Roy, Nirmal; Li, Donghui; Sun, Jianya; Nan, Peihong; Tang, Moon-Shong; Qu, Qingshan
2008 Feb;13(1):27-40, Biomarkers
— id: 79241, year: 2008, vol: 13, page: 27, stat: Journal Article,

Particulate matter inhibits DNA repair and enhances mutagenesis
Mehta, Manju; Chen, Lung-Chi; Gordon, Terry; Rom, William; Tang, Moon-Shong
2008 Dec 8;657(2):116-121, Mutation research
— id: 90028, year: 2008, vol: 657, page: 116, stat: Journal Article,

Using high throughput resequencing microarrays to detect mutations in genes involved in lung cancer
Piao, LC; Gunnison, A; Nadas, A; Chen, WC; Nonaka, D; Spivack, S; Pass, H; Rom, WN; Tang, MS
2008 DEC 11 ;4(3):159-159, Cancer biomarkers : section A of Disease markers
— id: 91475, year: 2008, vol: 4, page: 159, stat: Journal Article,

Gene profiling of normal human bronchial epithelial cells in response to asbestos and benzo(a)pyrene diol epoxide (BPDE)
Belitskaya-Levy, Ilana; Hajjou, Mustapha; Su, Wei-cheng; Yie, Ting-An; Tchou-Wong, Kam-Meng; Tang, Moon-shong; Goldberg, Judith D; Rom, William N
2007 ;26(4):281-294, Journal of environmental pathology, toxicology & oncology
— id: 76391, year: 2007, vol: 26, page: 281, stat: Journal Article,

Induction and prevention of carcinogenesis in rat skin exposed to space radiation
Burns, Fredric J; Tang, Moon-shong; Frenkel, Krystyna; Nadas, Arthur; Wu, Feng; Uddin, Ahmed; Zhang, Ronghe
2007 Jun;46(2):195-199, Radiation & environmental biophysics
— id: 159218, year: 2007, vol: 46, page: 195, stat: Journal Article,

Sequence specificity of Cr(III)-DNA adduct formation in the p53 gene: NGG sequences are preferential adduct-forming sites
Arakawa, Hirohumi; Wu, Feng; Costa, Max; Rom, William; Tang, Moon-Shong
2006 Mar;27(3):639-645, Carcinogenesis
— id: 63597, year: 2006, vol: 27, page: 639, stat: Journal Article,

Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair
Feng, Zhaohui; Hu, Wenwei; Hu, Yu; Tang, Moon-shong
2006 Oct 17;103(42):15404-15409, Proceedings of the National Academy of Sciences of the United States of America
— id: 70154, year: 2006, vol: 103, page: 15404, stat: Journal Article,

Malondialdehyde, a major endogenous lipid peroxidation product, sensitizes human cells to UV- and BPDE-induced killing and mutagenesis through inhibition of nucleotide excision repair
Feng, Zhaohui; Hu, Wenwei; Marnett, Lawrence J; Tang, Moon-shong
2006 Oct 10;601(1-2):125-136, Mutation research
— id: 69579, year: 2006, vol: 601, page: 125, stat: Journal Article,

Sensitive biomarker of polycyclic aromatic hydrocarbons (PAHs): urinary 1-hydroxyprene glucuronide in relation to smoking and low ambient levels of exposure
Hu, Y; Zhou, Z; Xue, X; Li, X; Fu, J; Cohen, B; Melikian, A A; Desai, M; Tang, M -S; Huang, X; Roy, N; Sun, J; Nan, P; Qu, Q
2006 Jul-Aug;11(4):306-318, Biomarkers
— id: 68305, year: 2006, vol: 11, page: 306, stat: Journal Article,

Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review
Arslan, Alan A; Gold, Leslie I; Mittal, Khushbakhat; Suen, Ting-Chung; Belitskaya-Levy, Ilana; Tang, Moon-Shong; Toniolo, Paolo
2005 Apr;20(4):852-863, Human reproduction
— id: 55957, year: 2005, vol: 20, page: 852, stat: Journal Article,

Model of transcriptional regulation of the BRCA1-NBR2 bi-directional transcriptional unit
Suen, Ting-Chung; Tang, Moon-Shong; Goss, Paul E
2005 May 1;1728(3):126-134, Biochimica & biophysica acta
— id: 56175, year: 2005, vol: 1728, page: 126, stat: Journal Article,

Trans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells: a possible mechanism for lipid peroxidation-induced carcinogenesis
Feng, Zhaohui; Hu, Wenwei; Tang, Moon-Shong
2004 Jul 8;101(23):8598-8602, Proceedings of the National Academy of Sciences of the United States of America
— id: 46002, year: 2004, vol: 101, page: 8598, stat: Journal Article,

Chromium(VI) enhances (+/-)-anti-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydro benzo[a]pyrene-induced cytotoxicity and mutagenicity in mammalian cells through its inhibitory effect on nucleotide excision repair
Hu, Wenwei; Feng, Zhaohui; Tang, Moon-shong
2004 Nov 9;43(44):14282-14289, Biochemistry
— id: 47759, year: 2004, vol: 43, page: 14282, stat: Journal Article,

Nickel (II) enhances benzo[a]pyrene diol epoxide-induced mutagenesis through inhibition of nucleotide excision repair in human cells: a possible mechanism for nickel (II)-induced carcinogenesis
Hu, Wenwei; Feng, Zhaohui; Tang, Moon-Shong
2004 Mar;25(3):455-462, Carcinogenesis
— id: 48182, year: 2004, vol: 25, page: 455, stat: Journal Article,

Differential effects of polycyclic aromatic hydrocarbons on transactivation of AP-1 and NF-kappaB in mouse epidermal cl41 cells
Li, Jingxia; Chen, Haobin; Ke, Qingdong; Feng, Zhaohui; Tang, Moon-Shong; Liu, Bingci; Amin, Shantu; Costa, Max; Huang, Chuanshu
2004 Jun;40(2):104-115, Molecular carcinogenesis
— id: 42690, year: 2004, vol: 40, page: 104, stat: Journal Article,

PI-3K and Akt are mediators of AP-1 induction by 5-MCDE in mouse epidermal Cl41 cells
Li, Jingxia; Chen, Haobin; Tang, Moon-Shong; Shi, Xianglin; Amin, Shantu; Desai, Dhimant; Costa, Max; Huang, Chuanshu
2004 Apr 12;165(1):77-86, Journal of cell biology
— id: 42691, year: 2004, vol: 165, page: 77, stat: Journal Article,

A critical role of PI-3K/Akt/JNKs pathway in benzo[a]pyrene diol-epoxide (B[a]PDE)-induced AP-1 transactivation in mouse epidermal Cl41 cells
Li, Jingxia; Tang, Moon-shong; Liu, Bingci; Shi, Xianglin; Huang, Chuanshu
2004 May 13;23(22):3932-3944, Oncogene
— id: 42695, year: 2004, vol: 23, page: 3932, stat: Journal Article,

Tobacco carcinogens and co-carcinogens damage the p53 and K-ras genes and reduce DNA repair capacity
Tang, MS
2004 NOV ;13(11):1968S-1968S, Cancer epidemiology biomarkers & prevention
— id: 50167, year: 2004, vol: 13, page: 1968S, stat: Journal Article,

DNA damage, repair, and mutation induction by (+)-Syn and (-)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxides in mouse cells
Yoon, Jung-Hoon; Besaratinia, Ahmad; Feng, Zhaohui; Tang, Moon-Shong; Amin, Shantu; Luch, Andreas; Pfeifer, Gerd P
2004 Oct 15;64(20):7321-7328, Cancer research
— id: 72108, year: 2004, vol: 64, page: 7321, stat: Journal Article,

Formation of trans-4-hydroxy-2-nonenal- and other enal-derived cyclic DNA adducts from omega-3 and omega-6 polyunsaturated fatty acids and their roles in DNA repair and human p53 gene mutation
Chung, Fung-Lung; Pan, Jishen; Choudhury, Sujata; Roy, Rabindra; Hu, Wenwei; Tang, Moon-shong
2003 Oct 29;531(1-2):25-36, Mutation research
— id: 72109, year: 2003, vol: 531, page: 25, stat: Journal Article,

Mutational spectrum and genotoxicity of the major lipid peroxidation product, trans-4-hydroxy-2-nonenal, induced DNA adducts in nucleotide excision repair-proficient and -deficient human cells
Feng, Zhaohui; Hu, Wenwei; Amin, Shantu; Tang, Moon-shong
2003 Jul 1;42(25):7848-7854, Biochemistry
— id: 39186, year: 2003, vol: 42, page: 7848, stat: Journal Article,

Effects of genomic context and chromatin structure on transcription-coupled and global genomic repair in mammalian cells
Feng, Zhaohui; Hu, Wenwei; Chasin, Lawrence A; Tang, Moon-shong
2003 Oct 15;31(20):5897-5906, Nucleic acids research
— id: 39040, year: 2003, vol: 31, page: 5897, stat: Journal Article,

Chromium(VI) exposure enhances polycyclic aromatic hydrocarbon-DNA binding at the p53 gene in human lung cells
Feng, Zhaohui; Hu, Wenwei; Rom, William N; Costa, Max; Tang, Moon-Shong
2003 Apr;24(4):771-778, Carcinogenesis
— id: 39234, year: 2003, vol: 24, page: 771, stat: Journal Article,

Preferential carcinogen-DNA adduct formation at codons 12 and 14 in the human K-ras gene and their possible mechanisms
Hu, Wenwei; Feng, Zhaohui; Tang, Moon-Shong
2003 Aug 26;42(33):10012-10023, Biochemistry
— id: 39105, year: 2003, vol: 42, page: 10012, stat: Journal Article,

Gene expression of primary human bronchial epithelial cells in response to coal dusts with different prevalence of coal workers' pneumoconiosis
Hu, Wenwei; Zhang, Qi; Su, Wei Cheng; Feng, Zhaohui; Rom, William; Chen, Lung Chi; Tang, Moonshong; Huang, Xi
2003 Jul 11;66(13):1249-1265, Journal of toxicology & environmental health. Pt. A
— id: 39145, year: 2003, vol: 66, page: 1249, stat: Journal Article,

The action of a dietary retinoid on gene expression and cancer induction in electron-irradiated rat skin
Burns, Fredric J; Chen, Shuaili; Xu, Guijuan; Wu, Feng; Tang, Moon-Shong
2002 Dec;43 Suppl:S229-S232, Journal of radiation research
— id: 72110, year: 2002, vol: 43 Suppl, page: S229, stat: Journal Article,

Molecular responses of mammalian cells to nickel and chromate exposure
Costa M; Salnikow K; Sutherland JE; Klutz T; Peng W; Tang M-S
Biomarkers of environmentally associated disease : technologies, concepts, and perspectives Boca Raton FL : Lewis Publishers, 2002,
— id: 4434, year: 2002, vol: , page: 261, stat: Chapter,

Preferential DNA damage and poor repair determine ras gene mutational hotspot in human cancer
Feng, Zhaohui; Hu, Wenwei; Chen, James X; Pao, Annie; Li, Haiying; Rom, William; Hung, Mien-Chie; Tang, Moon-shong
2002 Oct 16;94(20):1527-1536, Journal of the National Cancer Institute
— id: 39575, year: 2002, vol: 94, page: 1527, stat: Journal Article,

Transcription-coupled DNA repair is genomic context-dependent
Feng, Zhaohui; Hu, Wenwei; Komissarova, Elena; Pao, Annie; Hung, Mien-Chie; Adair, Gerald M; Tang, Moon-shong
2002 Apr 12;277(15):12777-12783, Journal of biological chemistry
— id: 39720, year: 2002, vol: 277, page: 12777, stat: Journal Article,

4-aminobiphenyl is a major etiological agent of human bladder cancer: evidence from its DNA binding spectrum in human p53 gene
Feng, Zhaohui; Hu, Wenwei; Rom, William N; Beland, Frederick A; Tang, Moon-shong
2002 Oct;23(10):1721-1727, Carcinogenesis
— id: 39577, year: 2002, vol: 23, page: 1721, stat: Journal Article,

N-hydroxy-4-aminobiphenyl-DNA binding in human p53 gene: sequence preference and the effect of C5 cytosine methylation
Feng, Zhaohui; Hu, Wenwei; Rom, William N; Beland, Frederick A; Tang, Moon-shong
2002 May 21;41(20):6414-6421, Biochemistry
— id: 32120, year: 2002, vol: 41, page: 6414, stat: Journal Article,

Transcription-coupled and transcription-independent repair of cyclobutane pyrimidine dimers in the dihydrofolate reductase gene
Hu, Wenwei; Feng, Zhaohui; Chasin, Lawrence A; Tang, Moon-shong
2002 Oct 11;277(41):38305-38310, Journal of biological chemistry
— id: 39609, year: 2002, vol: 277, page: 38305, stat: Journal Article,

The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma
Hu, Wenwei; Feng, Zhaohui; Eveleigh, Jamie; Iyer, Ganesh; Pan, Jishen; Amin, Shantu; Chung, Fung-Lung; Tang, Moon-Shong
2002 Nov;23(11):1781-1789, Carcinogenesis
— id: 39567, year: 2002, vol: 23, page: 1781, stat: Journal Article,

Inhibition of benzo(a)pyrene diol-epoxide-induced transactivation of activated protein 1 and nuclear factor kappaB by black raspberry extracts
Huang, Chuanshu; Huang, Yi; Li, Jingxia; Hu, Wenwei; Aziz, Robeena; Tang, Moon-shong; Sun, Nanjun; Cassady, John; Stoner, Gary D
2002 Dec 1;62(23):6857-6863, Cancer research
— id: 38406, year: 2002, vol: 62, page: 6857, stat: Journal Article,

Mapping polycyclic aromatic hydrocarbon and aromatic amine-induced DNA damage in cancer-related genes at the sequence level
Tang, Moon-shong; Pfeifer, Gerd P; Denissenko, Mikhail F; Feng, Zhaohui; Hu, Wenwei; Pao, Annie; Zheng, Yi; Zheng, Jessica B; Li, Haiying; Chen, James X
2002 Mar;205(1-2):103-113, International journal of hygiene & environmental health
— id: 39640, year: 2002, vol: 205, page: 103, stat: Journal Article,

The effect of C(5) cytosine methylation at CpG sequences on mitomycin-DNA bonding profiles
Li, VS; Tang, MS; Kohn, H
2001 APR ;9(4):863-873, Bioorganic & medicinal chemistry
— id: 98282, year: 2001, vol: 9, page: 863, stat: Journal Article,

Sequence-dependent interactions of two forms of UvrC with DNA helix-stabilizing CC-1065-N3-adenine adducts
Nazimiec, M; Lee, CS; Tang, YL; Ye, XC; Case, R; Tang, M
2001 SEP 18 ;40(37):11073-11081, Biochemistry
— id: 54893, year: 2001, vol: 40, page: 11073, stat: Journal Article,

Two forms of UvrC protein with different double-stranded DNA binding affinities
Tang Ms; Nazimiec M; Ye X; Iyer GH; Eveleigh J; Zheng Y; Zhou W; Tang YY
2001 Feb 9;276(6):3904-3910, Journal of biological chemistry
— id: 21266, year: 2001, vol: 276, page: 3904, stat: Journal Article,

Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: Similarities with the p53 mutation spectrum in smoking-associated lung cancers
Yoon, JH; Smith, LE; Feng, ZH; Tang, MS; Lee, CS; Pfeifer, GP
2001 OCT 1 ;61(19):7110-7117, Cancer research
— id: 98274, year: 2001, vol: 61, page: 7110, stat: Journal Article,

Cyclobutane pyrimidine dimers and bulky chemical DNA adducts are efficiently repaired in both strands of either a transcriptionally active or promoter-deleted APRT gene
Zheng, Y; Pao, A; Adair, G M; Tang , M
2001 May;276(20):16786-16796, Journal of biological chemistry
— id: 163498, year: 2001, vol: 276, page: 16786, stat: Journal Article,

C5 cytosine methylation at CpG sites enhances sequence selectivity of mitomycin C-DNA bonding
Li, V S; Reed, M; Zheng, Y; Kohn, H; Tang, M
2000 Mar 14;39(10):2612-2618, Biochemistry
— id: 133304, year: 2000, vol: 39, page: 2612, stat: Journal Article,

Mutation hotspots and DNA methylation
Pfeifer, GP; Tang, MS; Denissenko, MF
2000 JUN ;249(4):1-19, Current topics in microbiology & immunology
— id: 98298, year: 2000, vol: 249, page: 1, stat: Journal Article,

Both (+/-)syn- and (+/-)anti-7,12-dimethylbenz[a]anthracene-3,4-diol-1,2-epoxides initiate tumors in mouse skin that possess -CAA- to -CTA- mutations at Codon 61 of c-H-ras
Tang MS; Vulimiri SV; Viaje A; Chen JX; Bilolikar DS; Morris RJ; Harvey RG; Slaga TJ; DiGiovanni J
2000 Oct 15;60(20):5688-5695, Cancer research
— id: 39526, year: 2000, vol: 60, page: 5688, stat: Journal Article,

Influence of APOE genotype on familial aggregation of AD in an urban population
Devi, G; Ottman, R; Tang, M; Marder, K; Stern, Y; Tycko, B; Mayeux, R
1999 Sep 11;53(4):789-794, Neurology
— id: 74313, year: 1999, vol: 53, page: 789, stat: Journal Article,

A preliminary study of apolipoprotein E genotype and psychiatric manifestations of Alzheimer's disease
Ramachandran, G; Marder, K; Tang, M; Schofield, P W; Chun, M R; Devanand, D P; Stern, Y; Mayeux, R
1996 Jul;47(1):256-259, Neurology
— id: 74324, year: 1996, vol: 47, page: 256, stat: Journal Article,