Sanford M Miller, M.D.

In vitro performance evaluation of two rapid fluid infusion devices
Capan L.M.; Chakiryan N.; Miller S.M.; O'Neill D.K.; Jacobson J.; Martinez E.A.
2011 ;112(5 SUPPL 1):?-?, Anesthesia & analgesia
Introduction : Rapid infusion devices are becoming increasingly popular for the administration of warm fluids and blood in hypovolemic patients. A recently developed system, Thermacor 1200 (Smisson-Cartledge Biomedical LLC, Macon, GA), consists of a central device to which a disposable cartridge of fluid lines attaches. Performance characteristics of this device have yet to be evaluated. We compared the Thermacor 1200 with a currently utilized infusion device, FMS 2000 (Belmont Instrument Corp., Billerica, MA), to evaluate maximum flow rates, accuracy of actual versus set flow rates, fluid warming capabilities, and air bubble elimination. Methods : A ThermaCor 1200 and an FMS 2000, owned by our institution, were evaluated in vitro after being tested for proper functioning. FMS 2000 was tested with the packaged 4.5ft patient line, and Thermacor 1200 with packaged 3ft (TC3) and 6ft (TC6) patient lines. Maximum flow rates of lactated Ringer's (LR) and expired packed red blood cells (PRBCs) were measured with 22, 20, 18, 16, 14 and 8.5F gauge catheters, using a graduated cylinder and stopwatch. Flow rate accuracy was determined by comparing the actual versus displayed flow rates, for LR and PRBCs. Temperature was measured, at various flow rates, with an electronic probe (Wavetek 23XT, San Diego, CA) positioned 3cm from the distal port of the outflow tubing, for LR and PRBCs. Air elimination capability was determined, for LR only, by infusing fluid into an inverted 20mL syringe submerged in a bucket of water, and measuring the resulting air trapped in the syringe. All measurements were repeated six times. Data were analyzed using one-factor ANOVA, and the Tukey multiple comparisons method. Statistical significance was defined as p<0.05. Results : Maximum flow rates were higher with TC3 and TC6 than with FMS 2000 in most instances, especially when using larger catheter bores (Table 1). Flow rates were more accurate with TC3 and TC6 than with FMS 2000 for LR (1.4, 1.6, and 3.5% variance from target rate, respectively; p<.001) and for PRBCs (2.1, 2.6, and 5.9% variance from target rate, respectively; p<.001). Temperatures of delivered fluid were higher with TC3 and TC6 as compared to the FMS 2000 for LR (38.0, 37.8, and 36.8degreeC. respectively; p<.001) and PRBCs (38.2, 38.1, and 37.2degreeC, respectively; p<.001). Air was not detected in fluid infused from either device. Discussion : In this experiment, the performance of the Thermacor 1200, at both lengths of patient line, was superior to that of the FMS 2000 in that it infused LR and PRBCs at higher and more accurate flow rates, at higher temperatures. (Table presented)
— id: 146280, year: 2011, vol: 112, page: ?, stat: Journal Article,

Epidural analgesia in vascular surgery patients actively taking clopidogrel
Hodgson, R E; Miller, S M; Fortuna, A
2010 Aug;105(2):233-233, British journal of anaesthesia
— id: 112220, year: 2010, vol: 105, page: 233, stat: Journal Article,

Methylprednisolone in acute spinal cord injury: a tarnished standard
Miller, Sanford M
2008 Apr;20(2):140-142, Journal of neurosurgical anesthesiology
— id: 78692, year: 2008, vol: 20, page: 140, stat: Journal Article,

Antidotes in depth : Dantrolene sodium
Sutin, Kenneth M; Kaufman, Brian; Miller, Sanford M
Goldfrank's toxicologic emergencies New York : McGraw-Hill, 2006,
— id: 4566, year: 2006, vol: , page: 1037, stat: Chapter,

Neuromuscular blockers
Sutin, Kenneth M; Kaufman, Brian; Miller, Sanford M
Goldfrank's toxicologic emergencies New York : McGraw-Hill, 2006,
— id: 4565, year: 2006, vol: , page: 1024, stat: Chapter,

The use of cardioselective beta-blockers in a patient with idiopathic hypertrophic subaortic stenosis and chronic obstructive pulmonary disease
Bekker, Alex; Sorour, Khaled; Miller, Sanford
2002 Dec;14(8):589-591, Journal of clinical anesthesia
The beta-adrenergic receptor blocking drugs are commonly used in the treatment of patients with idiopathic hypertropic subaortic stenosis (IHSS). These drugs, however, are contraindicated in patients with chronic obstructive pulmonary disease (COPD). We report the anesthetic management of a patient with IHSS complicated by severe COPD. We concluded that the beta(1) selective, ultra-short acting beta-blocker, esmolol, can be used intraoperatively when both conditions are present. The pathophysiology and the commonly used anesthetic drugs and practices for treatment of patients with IHSS are reviewed
— id: 58977, year: 2002, vol: 14, page: 589, stat: Journal Article,

Monitoring for suspected pulmonary embolism
Capan LM; Miller SM
2001 Dec;19(4):673-703, Anesthesiology clinics of North America
It is fortunate that serious embolic phenomena are uncommon because, with the exception of neurosurgery in the sitting position and cardiac surgery, thoracic echocardiography and the precordial Doppler device, the most sensitive indicators of embolism, are seldom used. Vigilance is required of the anesthesiologist to recognize the rapid fall in end-tidal PCO2, the usual first indicator of a clinically significant PE. Any sudden deterioration in the patient's vital signs should include embolism in the differential diagnosis, particularly during procedures that carry a high risk of the complication
— id: 39461, year: 2001, vol: 19, page: 673, stat: Journal Article,

Trauma and burns
Capan LM; Miller SM
Clinical anesthesia Philadelphia : Lippincott Williams & Wilkins, 2001,
— id: 3358, year: 2001, vol: , page: 1255, stat: Chapter,

The use of propofol as an induction agent for halothane and isoflurane anesthesia in dogs
Bufalari, A; Miller, S M; Giannoni, C; Short, C E
1998 Jan-Feb;34(1):84-91, Journal of the American Animal Hospital Association
Cardiovascular, pulmonary, and quantitative electroencephalographic parameters were assessed in 12 anesthetized dogs to determine the compatibility of the injectable anesthetic propofol with halothane and isoflurane. No cases of apnea were observed during induction of anesthesia. An adequate level of anesthesia was established in each protocol as judged by both the lack of response to mechanical noxious stimuli (i.e., tail clamping) and evidence of reduction in total amplitude of brain wave activity. The initial propofol-mediated decrease in arterial blood pressure continued during either halothane (52.4%) or isoflurane (38%) anesthesia without a simultaneous increase in heart rate. The results of this study suggest that propofol, in combination with inhalant agents, can be used effectively and safely for canine anesthesia in veterinary practice
— id: 112221, year: 1998, vol: 34, page: 84, stat: Journal Article,

Anesthetics and neuromuscular blocking agents
Kaufman B; Sutin KM; Wahlander S; Miller SM
Goldfrank's Toxicologic emergencies Stamford, CT: Appleton & Lange, 1998,
— id: 2640, year: 1998, vol: , page: 873, stat: Chapter,

Trauma and burns
Capan LM; Miller SM
Clinical anesthesia Philadelphia PA: Lippincott-Raven, 1997,
— id: 2641, year: 1997, vol: , page: 1173, stat: Chapter,

Axillary dissection for tubular carcinoma of the breast
Berger AC; Miller SM; Harris MN; Roses DF
1996 ;2:204-208, Breast journal
— id: 25213, year: 1996, vol: 2, page: 204, stat: Journal Article,

Initial evaluation and resuscitation
Capan LM; Miller SM
1996 ;14(1):197-238, Anesthesiology clinics of North America
— id: 23501, year: 1996, vol: 14, page: 197, stat: Journal Article,

Vascular injuries
Miller SM; Capan LM
1995 ;13(1):187-216, Anesthesiology clinics of North America
— id: 8107, year: 1995, vol: 13, page: 187, stat: Journal Article,

Quantitative electroencephalographic evaluation to determine the quality of analgesia during anesthesia of horses for arthroscopic surgery
Miller, S M; Short, C E; Ekstrom, P M
1995 Mar;56(3):374-379, American journal of veterinary research
We compared the anesthetic combination of detomidine, ketamine, and halothane in control horses not undergoing apparently painful procedures with that in horses during arthroscopic surgery. The effectiveness of this regimen in suppressing neurologic response to surgery was, thus, evaluated. In this study, significant differences were not observed in electroencephalographic total amplitude, spectral edge, or beta-to-delta frequency ratio between surgically treated and nonsurgically treated (control) horses. On the basis of its attenuation of encephalographic responses, we conclude that detomidine (20 micrograms/kg of body weight, IV) and ketamine (2.2 mg/kg, IV) induction of anesthesia followed by maintenance with halothane is an effective regimen for control of pain in horses during arthroscopic surgery. The insignificant frequency changes observed without any other signs of inadequate anesthesia or pain may indicate a surgical stress response. We hypothesize that brain activity monitoring may give an earlier index to initiation of surgically induced stress than do hormonal responses, because endocrine alterations are not as rapidly perceived as is the electroencephalogram. Analysis of spectral edge frequency changes could be used to evaluate anesthetic regimens to find those that cause the least stress to the CNS during surgery in horses. Differences in species responses to an anesthetic agent or the regimen's effectiveness in prevention of pain during surgery may be identified by adoption of the study model. Evaluation of cardiopulmonary variables during anesthesia, with and without surgery, did not reveal any alterations that would be relevant to CNS responses.(ABSTRACT TRUNCATED AT 250 WORDS)
— id: 112222, year: 1995, vol: 56, page: 374, stat: Journal Article,

Perioperative anesthetic management of spine injuries
Capan LM; Miller SM; Sommer RM
1994 ;8(3):377-400, Problems in anesthesiology
— id: 45961, year: 1994, vol: 8, page: 377, stat: Journal Article,

Con: antiarrhythmic drugs should not be used to suppress ventricular ectopy in the perioperative period
Miller, S M; Mayer, R C
1994 Dec;8(6):701-703, Journal of cardiothoracic & vascular anesthesia
The alterations in autonomic tone imposed by the conduct of anesthesia and surgery predispose patients to ventricular ectopy. It is important to initially view any ectopy as a warning sign and promptly check the adequacy of ventilation and oxygenation. Most commonly an inadequate depth of anesthesia, surgical manipulation or electrolyte abnormality will be causative. Treatment of this underlying problem will usually suffice to terminate the ectopy. Importantly, many patients have preexisting, chronic, complex ventricular ectopy that gets revealed because of perioperative electrocardiographic monitoring. All available pharmacologic agents have significant adverse side effects. To date, all investigations examining outcome of suppression of ventricular ectopy show that successful suppression of ventricular ectopy was associated with an increased mortality. Although the prognosis for patients is worse when complex ventricular ectopy is associated with cardiac structural abnormalities, the optimal therapeutic approach to such patients remains undefined. Unless new data supporting the use of antiarrhythmic drugs in the perioperative setting become available, the risk to benefit ratio is considered unfavorable
— id: 112223, year: 1994, vol: 8, page: 701, stat: Journal Article,

Fat embolism
Capan LM; Miller SM; Patel KP
1993 ;11(1):25-54, Anesthesiology clinics of North America
— id: 45956, year: 1993, vol: 11, page: 25, stat: Journal Article,

Embolism II
Capan, Levon M.; Miller, Sanford M
Philadelphia : W. B. Saunders, 1993,
— id: 434, year: 1993, vol: , page: , stat: ,

Tumor, infectious, and foreign body emboli
Miller SM
1993 ;11(1):79-102, Anesthesiology clinics of North America
— id: 45958, year: 1993, vol: 11, page: 79, stat: Journal Article,

Embolism I
Capan, Levon M.; Miller, Sanford M
Philadelphia : W.B. Saunders Co., c1992,
— id: 572, year: 1992, vol: , page: , stat: ,

Comparison of recoveries from halothane vs isoflurane anesthesia in horses
Matthews, N S; Miller, S M; Hartsfield, S M; Slater, M R
1992 Aug 15;201(4):559-563, Journal of the American Veterinary Medical Association
Recovery from isoflurane anesthesia was shorter, with no difference in quality, compared with halothane anesthesia in 2 groups of horses. In 1 group, 12 horses scheduled for elective arthroscopy were randomly assigned to receive halothane or isoflurane for maintenance of anesthesia during surgery. In the other group, 6 horses received anesthesia only, on 2 occasions, with halothane on 1 occasion, and isoflurane on the other. Difference in the quality of recovery was not seen between isoflurane and halothane anesthesia in either group. In the group that had surgery, recovery to sternal position was significantly shorter when isoflurane was used. In the group not treated surgically, recovery to sternal and standing positions was significantly shorter with isoflurane
— id: 112224, year: 1992, vol: 201, page: 559, stat: Journal Article,

Trauma : anesthesia and intensive care
Capan LM; Miller SM; Turndorf H
Philadelphia : Lippincott, 1991,
— id: 802, year: 1991, vol: , page: , stat: ,

Management of facial injuries
Capan LM; Miller SM; Glickman R
Trauma : anesthesia and intensive care Philadelphia : Lippincott, 1990,
— id: 3406, year: 1990, vol: , page: 385, stat: Chapter,

Mangement of neck injuries
Capan LM; Miller SM; Turndorf H
Trauma : anesthesia and intensive care Philadelphia : Lippincott, 1990,
— id: 3407, year: 1990, vol: , page: 409, stat: Chapter,

Trauma overview
Capan LM; Miller SM; Turndorf H
Trauma : anesthesia and intensive care Philadelphia : Lippincott, 1990,
— id: 3408, year: 1990, vol: , page: 3, stat: Chapter,

Maximizing oxygenation during one-lung anesthesia
Capan LM; Turndorf H; Miller S
1990 ;2(4):282-304, Problems in anesthesiology
— id: 45964, year: 1990, vol: 2, page: 282, stat: Journal Article,

Trauma : anesthesia and intensive care
Capan, Levon M.; Miller, Sanford M.; Turndorf, Herman
Philadelphia : Lippincott, c1990,
— id: 238, year: 1990, vol: , page: , stat: ,

Management of central nervous system injuries
Miller SM
Trauma : anesthesia and intensive care Philadelphia : Lippincott, 1990,
— id: 3414, year: 1990, vol: , page: 321, stat: Chapter,

Adult respiratory distress syndrome and its management
Nacht A; Kahn RC; Miller SM
Trauma : anesthesia and intensive care Philadelphia : Lippincott, 1990,
— id: 3415, year: 1990, vol: , page: 725, stat: Chapter,

Management principles for microvascular surgery
Patel KP; Capan LM; Grant GJ; Miller SM
Trauma : anesthesia and intensive care Philadelphia : Lippincott, 1990,
— id: 3417, year: 1990, vol: , page: 547, stat: Chapter,

Musculoskeletal injuries
Patel KP; Capan LM; Grant GJ; Miller SM
Trauma : anesthesia and intensive care Philadelphia : Lippincott, 1990,
— id: 3418, year: 1990, vol: , page: 511, stat: Chapter,

Pro: Application of constant positive airway pressure to the nondependent lung is preferable to high-frequency ventilation for optimal oxygenation during pulmonary surgery
Capan, L M; Miller, S; Patel, K P
1987 Dec;1(6):584-588, Journal of cardiothoracic anesthesia
— id: 70094, year: 1987, vol: 1, page: 584, stat: Journal Article,

Cerebral protection by barbiturates and loop diuretics in head trauma: possible modes of action
Miller SM; Cottrell JE; Turndorf H; Ransohoff J
1980 May;56(3):305-313, Bulletin of the New York Academy of Medicine
— id: 45832, year: 1980, vol: 56, page: 305, stat: Journal Article,

Anesthesia and spinal cord lesions
Patel C; Miller SM; Chalon J; Turndorf H
1978 Dec;54(10):924-930, Bulletin of the New York Academy of Medicine
— id: 45850, year: 1978, vol: 54, page: 924, stat: Journal Article,