Biosketch / Results /

William M. Manger, M.D., Ph.D.

Clinical Professor;
Departments of Rehabilitation Medicine (Fac) and Medicine (Nephro Div)

Clinical Addresses

324 EAST 30 STREET
NEW YORK, NY 10016
Hours: Mon. 9:30 - 4; Tue. 9:30 - 4; Wed. 9:30 - 4; Thu. 9:30 - 4
Phone: 212-689-0873
Fax: 212-447-7032

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Medical Specialties

Internal Medicine

Medical Expertise

Preventive Medicine, Weight Management, General Internal Medicine

Languages

French

Insurance

Medicare

Insurance Disclaimer: Insurance listed above may not be accepted at all office locations. Please confirm prior to each visit. The information presented here may not be complete or may have changed.

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Research Summary

Previously, we showed that Dahl salt-sensitive (DS) rats increase renal vascular resistance (RVR) in response to a feeding of excessive salt (8% NaCl) before total peripheral resistance increases and before hypertension occurs. Failure of renal vasculature to dilate, as normally occurs in salt-resistant (DR) rats fed a high salt diet, may play an etiologic role in developing hypertension in DS rats. We also showed that renal vasculature in DS rats is hyperreactive to vasoconstrictors (angiotensin II and norepinephrine) and hyporeactive to vasodilators (ANP and nitroprusside). ANP, via stimulation of cell-bound receptors and nitroprusside (NP), directly via nitric oxide (NO) generation, cause renal vasodilation by generating guanosine 3'5'-cyclic monophosphate (cGMP). To determine if defective renal vasodilation in DS rats is due to impaired production of cGMP, we examined the influence of NP infusion and salt intake on RVR and cGMP excretion in DS and DR rats. Our results demonstrated that salt feeding and NP infusion increase cGMP excretion and decrease RVR in DR rats (P<0.01), and, although this relationship was less clear in DS rats, a reciprocal relationship was indicated between RVR and cGMP excretion in all animals studied. A relatively small increase in cGMP was associated with maximal renal vasodilation. Salt feeding and NP infusion caused less increase in cGMP excretion in DS than in DR rats (P<0.01). These studies support the concept that impairment in cGMP generation may play a primary role in the kidneys' inability in DS rats to vasodilate in response to increased salt intake. Such an impairment could contribute to salt retention and development of hypertension.

Research Interests

Renal Hemodynamics and Urinary cGMP Excretion

Research Keywords

cyclic GMP excretion, glomerular filtration rate, nitroprusside, radioimmunoassay, renal blood flow, renal vascular resistance

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Obesity Prevention in Young Schoolchildren: Results of a Pilot Study
Manger, William M; Manger, Lynn S; Minno, Alexander M; Killmeyer, Mike; Holzman, Robert S; Schullinger, John N; Roccella, Edward J
2012 Oct;82(10):462-468, Journal of school health
— id: 179138, year: 2012, vol: 82, page: 462, stat: Journal Article,

Renal functional, not morphological, abnormalities account for salt sensitivity in Dahl rats
Manger, William M; Simchon, Shlomoh; Stokes, Michael B; Reidy, Jason J; Kumar, Asok R; Baer, Leslie; Gallo, Gloria; Haddy, Francis J
2009 Mar;27(3):587-598, Journal of hypertension
— id: 101236, year: 2009, vol: 27, page: 587, stat: Journal Article,

'Cerebral vasculitis': Mistaken cause of fluctuating blood pressure and neurological manifestations
Manger, WM
2008 FEB ;73(3):354-359, Kidney international
— id: 87177, year: 2008, vol: 73, page: 354, stat: Journal Article,

Adverse drug reactions in patients with phaeochromocytoma: incidence, prevention and management
Eisenhofer, Graeme; Rivers, Graham; Rosas, Alejandro L; Quezado, Zena; Manger, William M; Pacak, Karel
2007 ;30(11):1031-1062, Drug safety
— id: 95341, year: 2007, vol: 30, page: 1031, stat: Journal Article,

An overview of pheochromocytoma: history, current concepts, vagaries, and diagnostic challenges
Manger, William M
2006 Aug;1073:1-20, Annals of the New York Academy of Sciences
— id: 95342, year: 2006, vol: 1073, page: 1, stat: Journal Article,

Diagnosis and management of pheochromocytoma - recent advances and current concepts
Manger, WM
2006 DEC ;70(12):S30-S35, Kidney international
— id: 69450, year: 2006, vol: 70, page: S30, stat: Journal Article,

The vagaries of pheochromocytomas
Manger, William M
2005 Oct;18(10):1266-1270, American journal of hypertension
— id: 95343, year: 2005, vol: 18, page: 1266, stat: Journal Article,

Effect of dietary NaCl on blood pressure (BP) response to intraventricular (ICV) infusion of NaCl in Dahl rats: Role of blood-brain barrier [BBB) and cGMP
Simchon, S; Golanov, E; Manger, WM
2005 NOV ;46(5):834-834, Hypertension
— id: 61456, year: 2005, vol: 46, page: 834, stat: Journal Article,

Malignant pheochromocytoma: current status and initiatives for future progress
Eisenhofer, Graeme; Bornstein, Stefan R; Brouwers, Frederieke M; Cheung, Nai-Kong V; Dahia, Patricia L; de Krijger, Ronald R; Giordano, Thomas J; Greene, Lloyd A; Goldstein, David S; Lehnert, Hendrik; Manger, William M; Maris, John M; Neumann, Hartmut P H; Pacak, Karel; Shulkin, Barry L; Smith, David I; Tischler, Arthur S; Young, William F Jr
2004 Sep;11(3):423-436, Endocrine-related cancer
— id: 95344, year: 2004, vol: 11, page: 423, stat: Journal Article,

Pheochromocytoma: diagnosis and management update
Manger, William M; Eisenhofer, Graeme
2004 Dec;6(6):477-484, Current hypertension reports
— id: 48080, year: 2004, vol: 6, page: 477, stat: Journal Article,

"Remembering Dr Ray W. Gifford, Jr (1923-2004) - In memoriam"
Manger, WM
2004 AUG ;44(2):111-111, Hypertension
— id: 46560, year: 2004, vol: 44, page: 111, stat: Journal Article,

Editorial: In search of pheochromocytomas
Manger, William M
2003 Sep;88(9):4080-4082, Journal of clinical endocrinology & metabolism
— id: 95346, year: 2003, vol: 88, page: 4080, stat: Journal Article,

Protective effects of dietary potassium chloride on hemodynamics of Dahl salt-sensitive rats in response to chronic administration of sodium chloride
Manger, William M; Simchon, Shlomoh; Stier, Charles T Jr; Loscalzo, Joseph; Jan, Kung-Ming; Jan, Rex; Haddy, Francis
2003 Dec;21(12):2305-2313, Journal of hypertension
— id: 95345, year: 2003, vol: 21, page: 2305, stat: Journal Article,

Hypertension update
Manger, William Muir
Secaucus NJ : Network for Continuing Medical Education, 2003,
— id: 894, year: 2003, vol: , page: , stat: ,

Pheochromocytoma
Manger, William M; Gifford, Ray W
2002 Jan-Feb;4(1):62-72, Journal of clinical hypertension (1999)
— id: 95347, year: 2002, vol: 4, page: 62, stat: Journal Article,

Effects of varying dietary potassium chloride on NaCl-dependent hemodynamics in RAPP/Dahl rats
Manger, WM; Simchon, S; Jan, KJ; Stier, CT; Loscalzo, J; Jan, R; Haddy, F
2002 JUN ;20(4):S263-S263, Journal of hypertension
— id: 38544, year: 2002, vol: 20, page: S263, stat: Journal Article,

Role of sodium transport through the blood brain barrier (BBB) in development of hypertension in Dahl salt-sensitive (DS) rats
Simchon, S; Golanov, E; Manger, WM
2002 JUN ;20(4):S130-S130, Journal of hypertension
— id: 38543, year: 2002, vol: 20, page: S130, stat: Journal Article,

100 questions and answers about hypertension
Manger, William Muir; Gifford, Ray W. (Ray Wallace)
Malden, MA : Blackwell Science, c2001,
— id: 737, year: 2001, vol: , page: , stat: ,

Beneficial or detrimental effects on hemodynamics depends on dose of dietary potassium in rapp dahl salt-sensitive (DS) rats
Manger, WM; Simchon, S; Jan, KM; Haddy, F; Stier, CT; Loscalzo, J; Jan, R
2000 OCT ;36(4):711-712, Hypertension
— id: 54421, year: 2000, vol: 36, page: 711, stat: Journal Article,

Renal functional and not morphological abnormalities are in prehypertensive salt-sensitive (non-modulator) Dahl rats
Simchon, S; Manger, W; Stokes, M; Kumar, A; Baer, L; Young, W; Gallo, G
2000 DEC ;18(6):S118-S118, Journal of hypertension
— id: 55269, year: 2000, vol: 18, page: S118, stat: Journal Article,

The 1997 medical controversy over the legalization of marihuana for medicine in the United States
Kassirer JP; Nahas GG; Sutin K; Manger W; Hyman G
Marihuana and medicine Totowa NJ : Humana Press, 1999,
— id: 3369, year: 1999, vol: , page: 59, stat: Chapter,

Protective hemodynamic effects of potassium chloride on brain and kidney of Dahl salt-sensitive rats
Manger, WM; Simchon, S; Jan, KM; Haddy, F
1999 MAR 15 ;13(5):A772-A772, FASEB journal
— id: 53931, year: 1999, vol: 13, page: A772, stat: Journal Article,

The medical use of marihuana and THC in perspective
Pace N; Frick HC; Sutin K; Manger W; Hyman G; Nahas G
Marihuana and medicine Totowa NJ : Humana Press, 1999,
— id: 4596, year: 1999, vol: , page: 767, stat: Chapter,

Handling 22NaCl by the blood-brain barrier and kidney: its relevance to salt-induced hypertension in dahl rats
Simchon S; Manger W; Golanov E; Kamen J; Sommer G; Marshall CH
1999 Jan;33(1 Pt 2):517-523, Hypertension
— id: 57357, year: 1999, vol: 33, page: 517, stat: Journal Article,

Renal morphology, hemodynamic, and biochemical studies of dahl salt-sensitive (DS) and salt-resistant (DS) rats
Manger, WM; Simchon, S; Stokes, MB; Gallo, G
1998 MAR 17 ;12(4):A42-A42, FASEB journal
— id: 53719, year: 1998, vol: 12, page: A42, stat: Journal Article,

Handling of Na-22 by the blood brain barrier (BBB) and renal tubule in Dahl salt-sensitive (DS) rats
Simchon, S; Manger, W; Golanov, E; Kamen, J; Sommer, G; Marshall, CH
1998 SEP ;32(3):615-615, Hypertension
— id: 53775, year: 1998, vol: 32, page: 615, stat: Journal Article,

Handling of Na-22 by the blood brain barrier (BBB) and renal tubule in Dahl salt-sensitive (DS) and salt-resistant (DR) rats
Simchon, S; Manger, WM; Golanov, E; Kamen, J; Sommer, G; Marshall, CH
1998 MAR 17 ;12(4):A90-A90, FASEB journal
— id: 53720, year: 1998, vol: 12, page: A90, stat: Journal Article,

The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
Black, HR; Cohen, JD; Kaplan, NM; Ferdinand, KC; Chobanian, AV; Dustan, HP; Gifford, RW; Moser, M; Sheps, SG; Agodoa, L; August, PA; Bakris, GL; Burt, V; Busse, W; Carter, BL; Chesley, FD; Cleeman, J; Cohn, JN; Cregler, LL; Crespo, C; Cushman, WC; Cutler, J; Darrow, MD; DeQuattro, VL; Devereux, RB; Dworkin, LD; Elliott, WJ; Epstein, M; Falkner, B; Ferrario, CM; Flack, JM; Frishman, W; Frohlich, ED; Green, LA; Grimm, RH; Hagberg, JM; Hall, WD; Handler, J; Havas, S; Hill, MN; Horan, MJ; Hsueh, WA; Hyman, BN; Izzo, JL; Jamerson, K; Kiley, JP; Kochar, MS; Kolasa, KM; Krakoff, LR; Levy, D; Lindheimer, MD; Luepker, RV; Malone, MEL; Massie, B; Materson, BJ; Merchant, J; Messerli, FH; Miller, NH; Moore, MA; MustoneAlexander, L; Oparil, S; Perry, HM; Pickering, TG; Pratt, JH; Ram, CVS; Randall, OS; Reed, JW; Roberts, RW; Roccella, EJ; Rogus, SD; Saunders, E; Schron, E; Schwartz, G; Sibai, BM; Snyder, D; Sowers, JR; Stamler, J; Temple, R; Textor, S; Thom, T; Vidt, DG; Weber, M; Weinberger, MH; Weinshilboum, R; Whelton, PK; Whisnant, JP; Wiebers, DO; Winston, MC; Wright, JT; Lenfant, C; Casser, L; Colman, PJ; Edwards, T; Feeley, DM; Gajewski, J; Levine, D; Manger, W; Marshall, EC; Nickey, WA; Robert, RW; Secrest, BG; Singer, EH; Whisnant, JP; Wilson, GJ; Young, JM; Bachman, JW; Campese, VM; Carr, AA; Hand, M; Holden, DC; Jamieson, MJ; Julius, S; Mensah, GA; Prisant, M; Sullivan, JM; Wilson, DJ; Morosco, G; Anderson, DE; Waugh, D
1997 ;157(21):2413-2446, Archives of internal medicine
— id: 109494, year: 1997, vol: 157, page: 2413, stat: Journal Article,

Marijuana is the wrong medicine
Nahas GG; Sutin K; Manger WM; Hyman G
1997 ;:A22-A22 March 11, Wall Street journal
— id: 45600, year: 1997, vol: , page: A22, stat: Journal Article,

Clinical and experimental pheochromocytoma
Manger, William Muir; Gifford, Ray W.; Manger, William Muir
Cambridge, Mass. : Blackwell Science, c1996,
— id: 550, year: 1996, vol: , page: , stat: ,

Impaired renal vasodilation and urinary cGMP excretion in Dahl salt-sensitive rats
Simchon S; Manger W; Blumberg G; Brensilver J; Cortell S
1996 Mar;27(3 Pt 2):653-657, Hypertension
— id: 7047, year: 1996, vol: 27, page: 653, stat: Journal Article,

Marijuana as medicine
Nahas GG; Manger WM
1995 Dec 20;274(23):1837-1838, JAMA
— id: 23754, year: 1995, vol: 274, page: 1837, stat: Journal Article,

IMPAIRED RENAL VASODILATION AND URINARY CGMP EXCRETION IN DAHL SALT-SENSITIVE RATS
SIMCHON, S; MANGER, W; BRENSILVER, J; CORTELL, S
1995 SEP ;26(3):569-569, Hypertension
— id: 86759, year: 1995, vol: 26, page: 569, stat: Journal Article,

Pheochromocytoma
Gifford RW Jr; Manger WM; Bravo EL
1994 Jun;23(2):387-404, Endocrinology & metabolism clinics of North America
— id: 63405, year: 1994, vol: 23, page: 387, stat: Journal Article,

HYPERTENSIVE CRISES INDUCED BY TREATMENT OF MALIGNANT PHEOCHROMOCYTOMA WITH A COMBINATION OF CYCLOPHOSPHAMIDE, VINCRISTINE, AND DACARBAZINE
WU, LT; DICPINIGAITIS, P; BRUCKNER, H; MANGER, W; AVERBUCH, S
1994 SEP 12 ;22(6):389-392, Medical & pediatric oncology
— id: 52372, year: 1994, vol: 22, page: 389, stat: Journal Article,

BAROREFLEX FAILURE - A DIAGNOSTIC CHALLENGE
MANGER, WM
1993 NOV 11 ;329(20):1494-1495, New England journal of medicine
— id: 52174, year: 1993, vol: 329, page: 1494, stat: Journal Article,

INTERACTIONS OF COCAINE AND ITS ANTIDOTES ON THE REGULATION OF THE BAROREFLEX
TROUVE, R; VIGOUROUX, E; LATOUR, C; MANGER, WM; NAHAS, G
1993 FEB 19 ;7(3):A416-A416, FASEB journal
— id: 54351, year: 1993, vol: 7, page: A416, stat: Journal Article,

ENHANCED RENAL VASCULAR-RESISTANCE AND SODIUM RETENTION IN PREHYPERTENSIVE DAHL SALT-SENSITIVE (DS) RATS
SIMCHON, S; MANGER, W; SHI, GS
1992 SEP ;20(3):428-428, Hypertension
— id: 51899, year: 1992, vol: 20, page: 428, stat: Journal Article,

IMPAIRED RENAL VASCULAR REACTIVITY IN PREHYPERTENSIVE DAHL SALT-SENSITIVE RATS
SIMCHON, S; MANGER, WM; SHI, GS; BRENSILVER, J
1992 OCT ;20(4):524-532, Hypertension
— id: 51874, year: 1992, vol: 20, page: 524, stat: Journal Article,

The First Irvine H. Page International Hypertension Research Symposium : the Page mosaic
Peart, W. S.; Manger, William Muir
Dallas, Tex. : American Heart Association, c1991,
— id: 397, year: 1991, vol: , page: , stat: ,

Dual hemodynamic mechanisms for salt-induced hypertension in Dahl salt-sensitive rats
Simchon S; Manger WM; Brown TW
1991 Jun;17(6 Pt 2):1063-1071, Hypertension
— id: 8460, year: 1991, vol: 17, page: 1063, stat: Journal Article,

Catecholamines, cocaine toxicity, and their antidotes in the rat
Trouve R; Nahas GG; Manger WM
1991 Feb;196(2):184-187, Proceedings of the Society for Experimental Biology & Medicine
— id: 8252, year: 1991, vol: 196, page: 184, stat: Journal Article,

Cocaine, catecholamines and cardiac toxicity
Nahas GG; Trouve R; Manger WM
1990 ;105:539-540, NIDA research monograph series
— id: 23757, year: 1990, vol: 105, page: 539, stat: Journal Article,

Cocaine, catecholamines and cardiac toxicity
Nahas GG; Trouve R; Manger WM
1990 ;94(2):77-81, Acta anaesthesiologica Scandinavica. Supplementum
— id: 23763, year: 1990, vol: 94, page: 77, stat: Journal Article,

Interactions of nimodipine and cocaine on endogenous catecholamines in the squirrel monkey
Trouve R; Nahas GG; Manger WM; Vinyard C; Goldberg S
1990 Mar;193(3):171-175, Proceedings of the Society for Experimental Biology & Medicine
— id: 23760, year: 1990, vol: 193, page: 171, stat: Journal Article,

Salt-induced hypertension in Dahl salt-sensitive rats. Hemodynamics and renal responses
Simchon S; Manger WM; Carlin RD; Peeters LL; Rodriguez J; Batista D; Brown T; Merchant NB; Jan KM; Chien S
1989 Jun;13(6 Pt 1):612-621, Hypertension
— id: 8379, year: 1989, vol: 13, page: 612, stat: Journal Article,

METABOLISM AND STORAGE OF CATECHOLAMINES IN RATS WITH PHEOCHROMOCYTOMA IMPLANTS
BUU, NT; KUCHEL, O; MANGER, W; HULSE, MC; CHUTE, RN
1986 OCT ;8(10):940-946, Hypertension
— id: 41549, year: 1986, vol: 8, page: 940, stat: Journal Article,

PHEOCHROMOCYTOMA
MANGER, WM
1986 SEP ;145(3):382-384, Western journal of medicine
— id: 41358, year: 1986, vol: 145, page: 382, stat: Journal Article,

DIAGNOSIS AND MANAGEMENT OF PHEOCHROMOCYTOMA
GIFFORD, RW; BRAVO, EL; MANGER, WM
1985 ;72(3-4):126-130, Cardiology
— id: 41201, year: 1985, vol: 72, page: 126, stat: Journal Article,

PSEUDOPHEOCHROMOCYTOMA AND CARDIAC-ARREST ASSOCIATED WITH PHENYLPROPANOLAMINE
HYAMS, JS; LEICHTNER, AM; BREINER, RG; HILL, DW; MCCOMB, RB; MANGER, WM
1985 JAN 20 ;253(11):1609-1610, JAMA
— id: 98583, year: 1985, vol: 253, page: 1609, stat: Journal Article,

"EFFECT OF EXCESS DIETARY NACL ON BP AND TISSUE CONCENTRATIONS OF NA+, K+ AND CATECHOLAMINES IN DAHL SALT SENSITIVE (S) AND RESISTANT (R) RATS"
BROWN, TW; WORTH, JM; WEBB, KB; VIRMANI, A; HULSE, MC; MANGER, WM
1984 ;43(3):505-505, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 41002, year: 1984, vol: 43, page: 505, stat: Journal Article,

Desensitization of beta-adrenergic receptors by pheochromocytoma
Tsujimoto G; Manger WM; Hoffman BB
1984 Apr;114(4):1272-1278, Endocrinology
— id: 62170, year: 1984, vol: 114, page: 1272, stat: Journal Article,

Heart imaging in the diagnosis of pheochromocytoma and assessment of catecholamine uptake
Manger WM; Hoffman BB
1983 Dec;24(12):1194-1196, Journal of nuclear medicine
— id: 65263, year: 1983, vol: 24, page: 1194, stat: Journal Article,

PHEOCHROMOCYTOMA AND THE REGULATION OF BETA-ADRENERGIC RECEPTORS
TSUJIMOTO, G; MANGER, WM; HOFFMAN, BB
1983 ;42(5):1365-1365, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 40708, year: 1983, vol: 42, page: 1365, stat: Journal Article,

Hypertension secondary to pheochromocytoma
Manger, W M; Gifford, R W Jr
1982 Mar;58(2):139-158, Bulletin of the New York Academy of Medicine
— id: 576402, year: 1982, vol: 58, page: 139, stat: Journal Article,

Effect of pheochromocytoma and hypophysectomy on blood pressure and catecholamines in NEDH rats
Manger, W M; Hulse, M C; Forsyth, M S; Chute, R N; Brown, C E; Webb, K; Sussman, R; Warren, S
1982 May-Jun;4(3 Pt 2):200-207, Hypertension
— id: 576602, year: 1982, vol: 4, page: 200, stat: Journal Article,

Pheochromocytoma and hypophysectomy: effects on blood pressure and catecholamines
Manger, W M; Hulse, M C; Forsyth, M S; Chute, R N; Brown, C E; Webb, K; Sussman, R; Warren, S
1982 Feb;30(7-8):601-602, Life sciences
— id: 163798, year: 1982, vol: 30, page: 601, stat: Journal Article,

Catecholamines in normal and abnormal cardiac function
Manger, William Muir
Basel ; New York : Karger, 1982,
— id: 107, year: 1982, vol: , page: , stat: ,

TISSUE AND BLOOD CATECHOLAMINES (CA) IN EXPERIMENTAL PHEOCHROMOCYTOMA (P)
Manger, WM; Hulse, MC; Chute, RN; Forsyth, ML; Webb, K; Vermani, A; Warren, S
1982 ;41(4):1345-1345, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 30467, year: 1982, vol: 41, page: 1345, stat: Journal Article,

EFFECT OF PHEOCHROMOCYTOMA AND HYPOPHYSECTOMY ON BLOOD-PRESSURE AND CATECHOLAMINES IN NEDH RATS
MANGER, WM; HULSE, MC; FORSYTH, MS; CHUTE, RN; BROWN, CE; WEBB, K; SUSSMAN, R; WARREN, S
1982 ;4(3):200-207, Hypertension
— id: 40421, year: 1982, vol: 4, page: 200, stat: Journal Article,

PHEOCHROMOCYTOMA AND HYPOPHYSECTOMY - EFFECTS ON BLOOD-PRESSURE AND CATECHOLAMINES
MANGER, WM; HULSE, MC; FORSYTH, MS; CHUTE, RN; BROWN, CE; WEBB, K; SUSSMAN, R; WARREN, S
1982 ;30(7-8):601-602, Life sciences
— id: 40461, year: 1982, vol: 30, page: 601, stat: Journal Article,

EFFECT OF PHEOCHROMOCYTOMA (P) TRANSPLANTATION AND HYPOPHYSECTOMY (HYPOX) ON BP AND CATECHOLAMINES (CA) IN NEDH RATS
FORSYTH, ML; MANGER, WM; WARREN, S; HULSE, MC; CHUTE, R; SUSSMAN, R
1981 ;40(3):412-412, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 40249, year: 1981, vol: 40, page: 412, stat: Journal Article,

Pheochromocytoma: diagnosis and management
Manger, W M; Gifford, R W Jr
1980 Feb;80(2):216-226, New York state journal of medicine
— id: 577752, year: 1980, vol: 80, page: 216, stat: Journal Article,

PHEOCHROMOCYTOMA - DIAGNOSIS AND MANAGEMENT
Manger, WM; Gifford, RW
1980 ;80(2):216-226, New York state journal of medicine
— id: 27928, year: 1980, vol: 80, page: 216, stat: Journal Article,

PLASMA AND PHEOCHROMOCYTOMA (P) CATECHOLAMINES (CA) AND BLOOD- PRESSURE (BP) IN NEDH RATS
Manger, WM; Warren, S; Sussman, RG; Hulse, MC; Forsyth, ML; Chute, RN
1980 ;39(3):1186-1186, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 28028, year: 1980, vol: 39, page: 1186, stat: Journal Article,

EFFECT OF NACL DIET ON BLOOD-PRESSURE AND TISSUE SODIUM AND POTASSIUM IN SPONTANEOUSLY HYPERTENSIVE AND NORMOTENSIVE RATS
Turino, PM; Manger, WM; Webb, KB; Hulse, MC; Sussman, RG; Forsyth, ML; Campbell, JP
1980 ;39(3):1188-1188, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 28029, year: 1980, vol: 39, page: 1188, stat: Journal Article,

VASOPRESSIN RELEASE DUE TO MANUAL RESTRAINT IN THE RAT - ROLE OF BODY COMPRESSION AND COMPARISON WITH OTHER STRESSFUL STIMULI
Husain, MK; Manger, WM; Rock, TW; Weiss, RJ; Frantz, AG
1979 ;104(3):641-644, Endocrinology
— id: 29990, year: 1979, vol: 104, page: 641, stat: Journal Article,

Autonomic hyperreflexia and its differentiation from pheochromocytoma
Manger, W M; Davis, S W; Chu, D S
1979 Apr;60(4):159-161, Archives of physical medicine & rehabilitation
— id: 487512, year: 1979, vol: 60, page: 159, stat: Journal Article,

CURRENT CONCEPTS OF PHEOCHROMOCYTOMA
Manger, WM; Gifford, RW
1978 ;3:289-28?, Cardiovascular medicine
— id: 29695, year: 1978, vol: 3, page: 289, stat: Journal Article,

EFFECT OF STRESS ON PLASMA CATECHOLAMINES (CA) IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR)
Manger, WM; Weiss, RA; Seides, R; Weiss, RJ; Hulse, M; Campbell, JP; Dufton, S
1978 ;37(3):735-735, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 29847, year: 1978, vol: 37, page: 735, stat: Journal Article,

Pheochromocytoma
Manger, William Muir; Gifford, Ray W
New York : Springer-Verlag, c1977,
— id: 183, year: 1977, vol: , page: , stat: ,

CORRELATION BETWEEN PLASMA AND TUMOR CATECHOLAMINES (CA) AND BLOOD-PRESSURE (BP) IN 38 PATIENTS WITH PHEOCHROMOCYTOMA
MANGER, WM; HART, CJ; HULSE, M; DUFTON, S
1977 ;36(3):328-328, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 39997, year: 1977, vol: 36, page: 328, stat: Journal Article,

OXYGEN CONSERVATION BY PROPRANOLOL AND INTRA-AORTIC BALLOON PUMPING IN NORMAL CANINE HEART
SPOTNITZ, HM; BEACH, PM; BREGMAN, D; TRUCCONE, N; PARODI, EN; MANGER, WM; MALM, JR
1977 ;22(5):453-462, Journal of surgical research
— id: 39966, year: 1977, vol: 22, page: 453, stat: Journal Article,

STUDIES ON CATECHOLAMINE METABOLISM IN SPONTANEOUSLY HYPERTENSIVE RATS (SHR)
Manger, CC; Manger, WM; Hart, CJ; Dufton, S; Hulse, M; Weiss, RJ; Weiss, RA; Rock, TW; Birkner, J; Soss, GA; Naftchi, NE
1976 ;35(3):209-209, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 28775, year: 1976, vol: 35, page: 209, stat: Journal Article,

NOREPINEPHRINE INFUSION IN NORMAL SUBJECTS AND PATIENTS WITH ESSENTIAL OR RENAL-HYPERTENSION - EFFECT ON BLOOD-PRESSURE, HEART-RATE, AND PLASMA CATECHOLAMINE CONCENTRATIONS
Manger, WM; Frohlich, ED; Gifford, RW; Dustan, HP
1976 ;16(2-3):129-141, Journal of clinical pharmacology
— id: 28713, year: 1976, vol: 16, page: 129, stat: Journal Article,

EFFECT OF TRANSPLANTING RENOMEDULLARY TISSUE INTO SPONTANEOUSLY HYPERTENSIVE RATS (SHR)
Manger, WM; Vanpraag, D; Weiss, RJ; Hart, CJ; Hulse, M; Rock, TW; Farber, SJ
1976 ;35(3):556-556, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 28784, year: 1976, vol: 35, page: 556, stat: Journal Article,

EFFECT OF STRENUOUS EXERCISE ON SPONTANEOUSLY HYPERTENSIVE RATS (SHR)
Rock, TW; Manger, WM; Wolinsky, H; Wolff, M; Hulse, M; Vanpraag, D; Pearson, J
1976 ;24(5):A619-A619, Clinical research
— id: 28718, year: 1976, vol: 24, page: A619, stat: Journal Article,

EFFECT OF TRANSPLANTING RENOMEDULLARY TISSUE INTO SPONTANEOUSLY HYPERTENSIVE RATS (SHR)
Weiss, RJ; Manger, WM; Vanpraag, D; Hart, CJ; Hulse, M; Soss, GA
1976 ;18(2):163-163, Pharmacologist
— id: 28738, year: 1976, vol: 18, page: 163, stat: Journal Article,

PLASMA VASOPRESSIN [VP) IN RATS - EFFECT OF STRESSFUL STIMULI
HUSAIN, K; MANGER, WM; ROCK, TW; WEISS, RJ; WEISS, RA; BIRKNER, J; DUFTON, S; HART, C; FRANTZ, AG
1975 ;23(5):A573-A573, Clinical research
— id: 98713, year: 1975, vol: 23, page: A573, stat: Journal Article,

HEMODYNAMIC AND HUMORAL CHARACTERISTICS OF HYPERTENSION INDUCED BY PROLONGED STELLATE GANGLION STIMULATION IN CONSCIOUS DOGS
LIARD, JF; TARAZI, RC; FERRARIO, CM; MANGER, WM
1975 ;36(3):455-464, Circulation research
— id: 48850, year: 1975, vol: 36, page: 455, stat: Journal Article,

INADEQUACY OF PLASMA CATECHOLAMINES AS AN INDEX OF ADRENERGIC ACTIVITY
Manger, WM; Estorff, IV; Davis, S; Chu, D; Wakim, K; Dufton, S
1975 ;34(3):723-723, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 28562, year: 1975, vol: 34, page: 723, stat: Journal Article,

PLASMA CATECHOLAMINES IN ESSENTIAL HYPERTENSION AND SPONTANEOUSLY HYPERTENSIVE RATS (SHR)
Manger, WM; Estorff, IV; Dufton, S
1975 ;34(3):399-399, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 28558, year: 1975, vol: 34, page: 399, stat: Journal Article,

PLASMA CATECHOLAMINES AND BLOOD-PRESSURE RESPONSE TO NOREPINEPHRINE INFUSION IN ESSENTIAL HYPERTENSION
Manger, WM; Gifford, RW; Frohlich, ED; Dustan, HP
1975 ;15(7):563-563, Journal of clinical pharmacology
— id: 28525, year: 1975, vol: 15, page: 563, stat: Journal Article,

CYCLIC ADENOSINE-MONOPHOSPHATE AND VASCULAR REACTIVITY IN SPONTANEOUSLY HYPERTENSIVE RATS
Triner, L; Vulliemoz, Y; Verosky, M; Manger, WM
1975 ;24(6):743-745, Biochemical pharmacology
— id: 28574, year: 1975, vol: 24, page: 743, stat: Journal Article,

EXCESSIVE THYROTROPIN CONCENTRATIONS IN CIRCULATION OF SPONTANEOUSLY HYPERTENSIVE RAT
WERNER, SC; MANGER, WM; RADICHEVICH, I; WOLFF, M; VONESTORFF, I
1975 ;148(4):1013-1017, Proceedings of the Society for Experimental Biology & Medicine
— id: 98737, year: 1975, vol: 148, page: 1013, stat: Journal Article,

MULTIPLE DIFFERENCES BETWEEN SPONTANEOUSLY HYPERTENSIVE (SHR) AND NORMOTENSIVE MALE KYOTO WISTAR RATS (K)
Manger, WM; Werner, SC; Freedman, LS; Dufton, S; Estorff, IV
1974 ;33(3):543-543, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 28389, year: 1974, vol: 33, page: 543, stat: Journal Article,

EFFECT OF AUTONOMIC DENERVATION AND HYPERBARIC OXYGENATION (OHP) ON PULMONARY NOREPINEPHRINE (NE)
Reich, T; Demeny, M; Manger, W; Naftchi, NE
1974 ;33(3):437-437, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 28387, year: 1974, vol: 33, page: 437, stat: Journal Article,

The effect of cold pressor test in man on serum immunoreactive dopamine-beta-hydroxylase and on dopamine-beta-hydroxylase activity
Freedman, L S; Ebstein, R P; Park, D H; Levitz, S M; Goldstein, M; Davis, S; Chu, D S; Manger, W M
1973 Nov;6(3):873-878, Research communications in chemical pathology & pharmacology
— id: 149719, year: 1973, vol: 6, page: 873, stat: Journal Article,

PRESUMABLE HYPOTHYROIDISM IN SPONTANEOUSLY HYPERTENSIVE RAT
MANGER, WM; WERNER, SC
1973 ;32(MAR):749-&, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 39871, year: 1973, vol: 32, page: 749, stat: Journal Article,

MULTIPLE DIFFERENCES BETWEEN SPONTANEOUSLY HYPERTENSIVE (SHR) AND NORMOTENSIVE WISTAR RATS (N)
MANGER, WM; WERNER, SC; DUFTON, S
1973 ;32(3):351-&, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 39883, year: 1973, vol: 32, page: 351, stat: Journal Article,

Tolerance of delta-9-tetrahydrocannabinol in the spontaneously hypertensive rat
Nahas GG; Schwartz IW; Adamec J; Manger WM
1973 Jan;142(1):58-60, Proceedings of the Society for Experimental Biology & Medicine
— id: 23795, year: 1973, vol: 142, page: 58, stat: Journal Article,

PATHOGENESIS OF PULMONARY O2 TOXICITY - ROLE OF AUTONOMIC INNERVATION AND CATECHOLAMINES
REICH, T; DEMENY, M; MANGER, W; NAFTCHI, NE
1973 ;48(4):206-206, Circulation
— id: 39847, year: 1973, vol: 48, page: 206, stat: Journal Article,

Comparison of improved fluorometric methods used to quantitate plasma catecholamines
Manger WM; Steinsland OS; Nahas GG; Wakim KG; Dufton S
1969 Dec;15(12):1101-1123, Clinical chemistry
— id: 23824, year: 1969, vol: 15, page: 1101, stat: Journal Article,

[Direct action of acidemia on the in vitro isolated and perfused adrenal medulla of dogs]
Milhaud A; Manger WM; Nahas GG
1967 ;161(6):1294-1302, Comptes rendus des seances de la Societe de Biologie & des ses Filiales
— id: 23851, year: 1967, vol: 161, page: 1294, stat: Journal Article,

Acidemia and catecholamine output of the isolated canine adrenal gland
Nahas GG; Zagury D; Milhaud A; Manger WM; Pappas GD
1967 Nov;213(5):1186-1192, American journal of physiology
— id: 23846, year: 1967, vol: 213, page: 1186, stat: Journal Article,

Effect of hypercapnic acidosis and of hypoxia on adrenal catecholamine output of the spinal dog
Cantu RC; Nahas GG; Manger WM
1966 Jun;122(2):434-437, Proceedings of the Society for Experimental Biology & Medicine
— id: 23858, year: 1966, vol: 122, page: 434, stat: Journal Article,

The effect of acidosis on sympatho-adrenal stimulation. Particular reference to cardiopulmonary bypass
Malm JR; Manger WM; Sullivan SF; Papper EM; Nahas GG
1966 Jul 11;197(2):121-125, JAMA
— id: 23854, year: 1966, vol: 197, page: 121, stat: Journal Article,

Hormones and hypertension
Manger, William Muir
Springfield, Ill., Thomas [c1966],
— id: 374, year: 1966, vol: , page: , stat: ,

Alterations in O2 uptake following hemorrhage in dogs
Nahas GG; Triner L; Small HS; Manger WM; Habif DV
1966 May;210(5):1009-1014, American journal of physiology
— id: 23860, year: 1966, vol: 210, page: 1009, stat: Journal Article,

[THE CONTROL OF ACIDOSIS AND THE USE OF NEUTRALIZED CITRATED BLOOD IN CARDIAC SURGERY]
NAHAS, G G; MALM, J R; MANGER, W M; VEROSKY, M; SULLIVAN, F
1964 Mar;72:657-660, La Presse medicale
— id: 536152, year: 1964, vol: 72, page: 657, stat: Journal Article,

CONTROL OF ACIDOSIS AND THE USE OF TITRATED ACD BLOOD IN OPEN-HEART SURGERY
NAHAS, G G; MALM, J R; MANGER, W M; VEROSKY, M; SULLIVAN, S F
1964 Dec;160:1049-1056, Annals of surgery
— id: 536102, year: 1964, vol: 160, page: 1049, stat: Journal Article,

TRANSFUSION ACIDOSIS
NAHAS, G G; MANGER, W M; ULTMANN, J E
1964 ;19:610-616, Bibliotheca haematologica
— id: 536162, year: 1964, vol: 19, page: 610, stat: Journal Article,

Effect of pH control and increased O2 delivery on the course of hemorrhagic shock
MANGER, W M; NAHAS, G G; HASSAM, D; HABIF, D V; PAPPER, E M
1962 Sep;156:503-510, Annals of surgery
— id: 536272, year: 1962, vol: 156, page: 503, stat: Journal Article,

Buffering of hypercapnic acidosis by sodium carbonate
NAHAS, G G; HASSAM, D; HOLMDAHL, M H; MANGER, W M
1962 Jan;202:73-76, American journal of physiology
— id: 536322, year: 1962, vol: 202, page: 73, stat: Journal Article,

[Experimental study of transfusion acidosis]
NAHAS, G G; MANGER, W M; MITTELMAN, A; ULTMAN, J E
1962 Mar-Apr;2:182-194, Nouvelle revue francaise d'hematologie
— id: 536302, year: 1962, vol: 2, page: 182, stat: Journal Article,

Effect of pH control on the course of hemorrhagic shock
HASSAM, D; NAHAS, G G; MANGER, W M; HABIF, D V
1961 ;12:76-77, Surgical forum
— id: 536442, year: 1961, vol: 12, page: 76, stat: Journal Article,

Chemical quantitation of epinephrine and norepinephrine in plasma; a clinical and experimental study; a study of epinephrine and norepinephrine: their plasma concentration in hypertension, shock, and mental disease, with some metabolic studies. By William Muir Manger, Khalil G. Wakim, and Jesse L. Bollman
Manger, William Muir
Springfield, Ill., Thomas [1959],
— id: 348, year: 1959, vol: , page: , stat: ,