Shari I Lusskin, M.D.

Update on Depression in Pregnancy
Khan, Sabrina J; Lusskin, Shari I
2010 ;35(6):27-31, Female patient
— id: 141504, year: 2010, vol: 35, page: 27, stat: Journal Article,

Treating depression in pregnancy. [Italian]
Lusskin S.I.; Turco J.
2008 ;30(3):61-67, Giornale Italiano di Ostetricia e Ginecologia
— id: 79428, year: 2008, vol: 30, page: 61, stat: Journal Article,

Screening for maternal depression in a low education population using a two item questionnaire
Cutler, C B; Legano, L A; Dreyer, B P; Fierman, A H; Berkule, S B; Lusskin, S I; Tomopoulos, S; Roth, M; Mendelsohn, A L
2007 ;10(6):277-283, Archives of women's mental health
OBJECTIVE: To assess a two-question screening tool, the Patient Health Questionnaire-2 (PHQ-2), for identifying depressive symptomatology in economically disadvantaged mothers of children in pediatric settings and to explore risk factors associated with a positive depression screen. METHODS: A convenience sample of mothers was enrolled at an inner city well-child clinic with children age 3 days to 5 years. The PHQ-2 and Edinburgh Postnatal Depression Scale (EPDS) (as reference scale) were completed. RESULTS: Ninety-four mothers participated. Agreement of the PHQ-2 and EPDS was moderate. The sensitivity of the PHQ-2 for identifying a positive screen on the EPDS was 43.5%; the specificity was 97.2%. The sensitivity of the PHQ-2 was higher for mothers with education beyond high school compared to those with less education. Perceived lack of support with child care and having two or more children were associated with a positive screen. The rate of positive screen was similar for mothers with infants and with older children. CONCLUSION: Given the low sensitivity of the PHQ-2 in lower educated mothers, additional research in populations with varying sociodemographic characteristics is indicated. Similar rates of symptoms for mothers within and beyond the postpartum period and mothers previously screened support the need for periodic screening
— id: 78733, year: 2007, vol: 10, page: 277, stat: Journal Article,

Maternal anxiety and ultrasound markers for aneuploidy in a multiethnic population
Lee, M J; Roman, A S; Lusskin, S; Chen, D; Dulay, A; Funai, E F; Monteagudo, A
2007 Jan;27(1):40-45, Prenatal diagnosis
OBJECTIVE: Discussion of isolated ultrasound (US) markers for fetal aneuploidy can provoke significant patient anxiety. The objective of this study is to quantify maternal anxiety associated with the detection of these markers. METHODS: All patients undergoing routine second-trimester US examination for fetal anatomical survey over a one-year period were administered the State-Trait Anxiety Inventory (STAI) for Adults before and after the procedure. Women with isolated fetal markers for aneuploidy were notified of the findings but discouraged from pursuing amniocentesis. Rates of normal US examination, aneuploidy markers, anomalies, amniocentesis, and pregnancy outcomes were assessed across the ethnic groups. Pre- and post-ultrasound STAI surveys were scored and standardized with previously established norms. Student t-tests, Chi-square, and analysis of variance (ANOVA) were used where appropriate. RESULTS: Among the 798 patients tested, 57% were Hispanic, 30% were Asian, 6% were Black, and 7% were White. Maternal anxiety level was decreased in women after a normal US. The anxiety level increased with aneuploidy markers and was the highest with anomalies. Aneuploidy markers were more common among Hispanic and Asian fetuses, without any associated aneuploidy. Women with isolated aneuploidy markers underwent amniocentesis as often as women with advanced maternal age. CONCLUSION: The detection and communication of isolated aneuploidy markers is associated with increased maternal anxiety and unnecessary amniocentesis
— id: 141337, year: 2007, vol: 27, page: 40, stat: Journal Article,

"Perinatal depression: Hiding in plain sight": Erratum
Lusskin, Shari I; Pundiak, Tara M; Habib, Sally M
2007 ;52(11):692-692, Canadian journal of psychiatry
Reports an error in 'Perinatal depression: Hiding in plain sight' by Shari I. Lusskin, Tara M. Pundiak and Sally M. Habib (The Canadian Journal of Psychiatry / La Revue Canadienne de Psychiatrie, 2007[Aug], Vol 52[8], 479-488). It has come to the authors' attention that the prevalence of postpartum depression among new immigrants to Israel was incorrectly reported as 22.6% rather than 35.8%. The prevalence rate for the entire study group of 288 Israeli women was 22.6%; two-thirds of the entire group reported symptoms during pregnancy. Among new Russian immigrants, the prevalence of postpartum depression was 35.8%, twice the rate (16.9%) of Israeli-born women; rates of antenatal symptoms for this subgroup were not reported. These findings highlight the importance of assessing individual risk factors for perinatal depression. The Canadian Journal of Psychiatry regrets the error and any inconvenience it may have caused. (The following abstract of the original article appeared in record 2007-14436-002). Objective: To promote prompt identification and treatment of perinatal depression and enhance preventive care for women at risk. Methods: Using MEDLINE and PubMed searches, we reviewed the recent research on the origins, course, and consequences of pregnancy-related depression. Results: Depressive disorders are more common in pregnancy and postpartum than widely assumed, and there is no predictable protective effect of pregnancy. Relapse rates are high, and the postpartum period represents a time of increased vulnerability to depression. Conclusion: Early identification and treatment of perinatal depression will minimize morbidity and mortality for the woman, the child, and the family.
— id: 75227, year: 2007, vol: 52, page: 692, stat: Journal Article,

Perinatal depression: hiding in plain sight
Lusskin, Shari I; Pundiak, Tara M; Habib, Sally M
2007 Aug;52(8):479-488, Canadian journal of psychiatry
OBJECTIVE: To promote prompt identification and treatment ofperinatal depression and enhance preventive care for women at risk. METHODS: Using MEDLINE and PubMed searches, we reviewed the recent research on the origins, course, and consequences of pregnancy-related depression. RESULTS: Depressive disorders are more common in pregnancy and postpartum than widely assumed, and there is no predictable protective effect of pregnancy. Relapse rates are high, and the postpartum period represents a time of increased vulnerability to depression. CONCLUSION: Early identification and treatment ofperinatal depression will minimize morbidity and mortality for the woman, the child, and the family
— id: 75397, year: 2007, vol: 52, page: 479, stat: Journal Article,

NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of amphetamine and methamphetamine
Golub, Mari; Costa, Lucio; Crofton, Kevin; Frank, Deborah; Fried, Peter; Gladen, Beth; Henderson, Rogene; Liebelt, Erica; Lusskin, Shari; Marty, Sue; Rowland, Andrew; Scialli, John; Vore, Mary
2005 Dec;74(6):471-584, Birth defects research. Pt B. Developmental & reproductive toxicology
— id: 61182, year: 2005, vol: 74, page: 471, stat: Journal Article,

NTP-CERHR Expert Panel Report on the reproductive and developmental toxicity of methylphenidate
Golub, Mari; Costa, Lucio; Crofton, Kevin; Frank, Deborah; Fried, Peter; Gladen, Beth; Henderson, Rogene; Liebelt, Erica; Lusskin, Shari; Marty, Sue; Rowland, Andrew; Scialli, John; Vore, Mary
2005 Aug;74(4):300-381, Birth defects research. Pt B. Developmental & reproductive toxicology
— id: 61183, year: 2005, vol: 74, page: 300, stat: Journal Article,

Treatment of psychiatric disorders in pregnancy
Misri, Shaila; Lusskin, Shari I
2005;:- [Web site], 2005-, UpToDate
— id: 150907, year: 2005, vol: , page: , stat: Web Site,

Use of psychotropic medications in breastfeeding women
Misri, Shaila; Lusskin, Shari I
2005;:- [Web site], 2005-, UpToDate
— id: 150908, year: 2005, vol: , page: , stat: Web Site,

The Obstetrics Patient
Wyszynski, Antoinette Ambrosino; Lusskin, Shari I
Manual of psychiatric care for the medically ill Washington, DC, US: American Psychiatric Publishing, Inc., 2005,
(from the chapter) The selective serotonin reuptake inhibitors (SSRIs) have replaced benzodiazepines, sedatives, and tricyclic antidepressants as first-line medications for anxiety and depressive disorders in pregnant women. Before their arrival, the emphasis was on 'making do' until the infant was delivered, because of worries about teratogenicity. The SSRIs have streamlined, but not eliminated, clinical decision making. The risks to the fetus shift over time, creating uncertainty about intervention. Pregnancy dysregulates occult and established psychiatric illness, particularly in the postpartum period. Several management problems arise when treating women of childbearing age. The permutations of these treatment decisions can be dizzying. For the depressed patient, the path to treatment has been made easier by the Consensus Guideline Project for the treatment of depression. (Altshuler et al. 2001) (see the sections in this chapter on depression occurring in the conception, pregnancy, and postpartum periods). For the patient with bipolar disorder, a consensus guideline for the management of bipolar disorder in pregnant and postpartum women is also available (Yonkers et al. 2004). Unfortunately, parallel consensus studies do not exist for managing schizophrenia and anxiety disorders in pregnancy. As an alternative, we have gathered the recommendations from the current literature Box 7-1 highlights the numerous resources available for these patients, organizing the data according to to assist the clinician in assessing the safety of various four stages of the reproductive cycle: Phase I, Conception; Phase II, Pregnancy; Phase III, Postpartum; and Phase IV, Breastfeeding.
— id: 3793, year: 2005, vol: , page: 115, stat: Chapter,

Prolactin elevation with ziprasidone
Lusskin, Shari I; Cancro, Robert; Chuang, Linda; Jacobson, Jessica
2004 Oct;161(10):1925-1925, American journal of psychiatry
— id: 45323, year: 2004, vol: 161, page: 1925, stat: Journal Article,

Postpartum blues and depression
Misri, Shaila; Lusskin, Shari I
2004;:- [Web site], 2004-, UpToDate
— id: 150905, year: 2004, vol: , page: , stat: Web Site,

Postpartum psychosis
Misri, Shaila; Lusskin, Shari I
2004;:- [Web site], 2004-, UpToDate
— id: 150903, year: 2004, vol: , page: , stat: Web Site,

Psychiatric disorders in pregnancy
Misri, Shaila; Lusskin, Shari I
2004;:- [Web site], 2004-, UpToDate
— id: 150904, year: 2004, vol: , page: , stat: Web Site,

"Prolonged post-partum blues, depression or psychosis? The Andrea Yates Lesson"
Lusskin, SI
2002 Apr;11(3):S6-, Journal of women's health & gender-based medicine
— id: 28190, year: 2002, vol: 11, page: S6, stat: Journal Article,

The epidemiology of postpartum depression
Lusskin S
2001 ;3(Suppl 2):2-2 abstract S7, Archives of women's mental health
— id: 25636, year: 2001, vol: 3, page: 2, stat: Journal Article,

Pregnancy-related psychiatric disorders
Lusskin SI
1999 ;5(Pt. 2):15-23, Hospital physician: obstetrics & gynaecology board review manual
— id: 25635, year: 1999, vol: 5, page: 15, stat: Journal Article,

Depression in the perimenopause
Lusskin SI
1998 Spring;?:?-?, Journal of the Bellevue Obstetrical & Gynecological Society
— id: 25634, year: 1998, vol: ?, page: ?, stat: Journal Article,

Electrocyclic ring opening of halocyclopropanes
Markgraf JH; Finkelstein M; Leonard KJ; Lusskin SI
1985 ;62(3):265-266, Journal of chemical education
— id: 25633, year: 1985, vol: 62, page: 265, stat: Journal Article,

Synthesis of racemic disparlure
Markgraf JH; Lusskin SI; Mcdonald EC; Volpp BD
1983 ;9(2):211-218, Journal of chemical ecology
A six-step, convergent synthesis was developed for racemic (Z)-7,8-epoxy-2-methyloctadecane (disparlure), the sex pheromone of the gypsy moth (Porthetria dispar, a pest on broad leaf trees). The key step is a Wittig reaction between 6-methylheptanal and triphenylundecylphosphonium bromide effected by potassium carbonate in the presence of a crown ether
— id: 25632, year: 1983, vol: 9, page: 211, stat: Journal Article,