Peter A Lopez

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Peter A Lopez

Research Assistant Professor;
Department of Pathology (Pathology) and Structural Biology

Contact Info

Address
540 First Avenue
Floor 3 Room Lab 8
Skirball Institute
New York, NY 10016

212-263-0635, 212-263-5907
212-263-2150
Peter.Lopez@med.nyu.edu


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Research Interests

I have been involved in the field of flow cytometry since 1977. My focus has been to help facilitate the use of this technology to answer biological questions. I am privileged to have been asked to contribute my cytometric expertise to a wide range of studies including the automated detection of malignant or premalignant cells, hematopoietic stem cell isolation, the study of T-cell receptor function, the detection and study of apoptotic cells,and most recently the study of effects of HIV infection in varied cell types.

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search#about

Protocadherin-18 is a novel differentiation marker and an inhibitory signaling receptor for CD8(+) effector memory T cells
Vazquez-Cintron, Edwin J; Monu, Ngozi R; Burns, Jeremy C; Blum, Roy; Chen, Gregory; Lopez, Peter; Ma, Jennifer; Radoja, Sasa; Frey, Alan B
2012 ;7(5):e36101-e36101 e36101, PLoS ONE
— id: 166801, year: 2012, vol: 7, page: e36101, stat: Journal Article,

Pro-tumorigenic effects of miR-31 loss in mesothelioma
Ivanov, Sergey V; Goparaju, Chandra M V; Lopez, Peter; Zavadil, Jiri; Toren-Haritan, Ginat; Rosenwald, Shai; Hoshen, Moshe; Chajut, Ayelet; Cohen, Dalia; Pass, Harvey I
2010 Jul 23;285(30):22809-22817, Journal of biological chemistry
— id: 138201, year: 2010, vol: 285, page: 22809, stat: Journal Article,

Mechanisms of gastrointestinal CD4+ T-cell depletion during acute and early human immunodeficiency virus type 1 infection
Mehandru, Saurabh; Poles, Michael A; Tenner-Racz, Klara; Manuelli, Victoria; Jean-Pierre, Patrick; Lopez, Peter; Shet, Anita; Low, Andrea; Mohri, Hiroshi; Boden, Daniel; Racz, Paul; Markowitz, Martin
2007 Jan;81(2):599-612, Journal of virology
— id: 156640, year: 2007, vol: 81, page: 599, stat: Journal Article,

In vitro modeling of the HIV-macrophage reservoir
Brown, Amanda; Zhang, Hao; Lopez, Peter; Pardo, Carlos A; Gartner, Suzanne
2006 Nov;80(5):1127-1135, Journal of leukocyte biology
— id: 73130, year: 2006, vol: 80, page: 1127, stat: Journal Article,

Recombinant extracellular domains of tetraspanin proteins are potent inhibitors of the infection of macrophages by human immunodeficiency virus type 1
Ho, Siu-Hong; Martin, Francine; Higginbottom, Adrian; Partridge, Lynda J; Parthasarathy, Varadarajan; Moseley, Gregory W; Lopez, Peter; Cheng-Mayer, Cecilia; Monk, Peter N
2006 Jul;80(13):6487-6496, Journal of virology
— id: 73129, year: 2006, vol: 80, page: 6487, stat: Journal Article,

Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection
Mehandru, Saurabh; Poles, Michael A; Tenner-Racz, Klara; Jean-Pierre, Patrick; Manuelli, Victoria; Lopez, Peter; Shet, Anita; Low, Andrea; Mohri, Hiroshi; Boden, Daniel; Racz, Paul; Markowitz, Martin
2006 Dec;3(12):e484-e484 e484, PLoS medicine
— id: 156641, year: 2006, vol: 3, page: e484, stat: Journal Article,

The intracellular localization of amyloid beta protein precursor (AbetaPP) intracellular domain associated protein-1 (AIDA-1) is regulated by AbetaPP and alternative splicing
Ghersi, Enrico; Vito, Pasquale; Lopez, Peter; Abdallah, Mona; D'Adamio, Luciano
2004 Feb;6(1):67-78, Journal of Alzheimer's Disease
— id: 73126, year: 2004, vol: 6, page: 67, stat: Journal Article,

alpha-defensins released into stimulated CD8+ T-cell supernatants are likely derived from residual granulocytes within the irradiated allogeneic peripheral blood mononuclear cells used as feeders
Zaharatos, Gerasimos J; He, Tian; Lopez, Peter; Yu, Wenjie; Yu, Jian; Zhang, Linqi
2004 Aug 15;36(5):993-1005, Journal of acquired immune deficiency syndromes. JAIDS
— id: 73127, year: 2004, vol: 36, page: 993, stat: Journal Article,

Retraction of an interpretation
Zhang, Linqi; Lopez, Peter; He, Tian; Yu, Wenjie; Ho, David D
2004 Jan 23;303(5657):467-467, Science
— id: 107962, year: 2004, vol: 303, page: 467, stat: Journal Article,

Autosomal recessive hypercholesterolemia protein interacts with and regulates the cell surface level of Alzheimer's amyloid beta precursor protein
Noviello, Cristiana; Vito, Pasquale; Lopez, Peter; Abdallah, Mona; D'Adamio, Luciano
2003 Aug 22;278(34):31843-31847, Journal of biological chemistry
— id: 73124, year: 2003, vol: 278, page: 31843, stat: Journal Article,

Relating personal PM and PM-associated elemental carbon exposures to cardiovascular and pulmonary symptoms in a high-risk subpopulation
Kendall, M; Hsu, SI; Lopez, P; Wallace, L; Lippman, M
2002 JUL ;13(4):023-400, Epidemiology
— id: 98250, year: 2002, vol: 13, page: 023, stat: Journal Article,

The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling
Roncarati, Roberta; Sestan, Nenad; Scheinfeld, Meir H; Berechid, Bridget E; Lopez, Peter A; Meucci, Olimpia; McGlade, Jane C; Rakic, Pasko; D'Adamio, Luciano
2002 May 14;99(10):7102-7107, Proceedings of the National Academy of Sciences of the United States of America
— id: 73123, year: 2002, vol: 99, page: 7102, stat: Journal Article,

Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP)
Scheinfeld, Meir H; Roncarati, Roberta; Vito, Pasquale; Lopez, Peter A; Abdallah, Mona; D'Adamio, Luciano
2002 Feb 1;277(5):3767-3775, Journal of biological chemistry
— id: 73122, year: 2002, vol: 277, page: 3767, stat: Journal Article,

Contribution of human alpha-defensin 1, 2, and 3 to the anti-HIV-1 activity of CD8 antiviral factor
Zhang, Linqi; Yu, Wenjie; He, Tian; Yu, Jian; Caffrey, Rebecca E; Dalmasso, Enrique A; Fu, Siyu; Pham, Thang; Mei, Jianfeng; Ho, Jaclyn J; Zhang, Wenyong; Lopez, Peter; Ho, David D
2002 Nov 1;298(5595):995-1000, Science
— id: 67202, year: 2002, vol: 298, page: 995, stat: Journal Article,

Commercial high speed machines open new opportunities in high throughput flow cytometry (HTFC)
Ashcroft, R G; Lopez, P A
2000 Sep 21;243(1-2):13-24, Journal of immunological methods
— id: 73121, year: 2000, vol: 243, page: 13, stat: Journal Article,

High-speed sorting using the Cytomation MoFlo
Lopez PA
In living color : protocols in flow cytometry and cell sorting Berlin : Springer, 2000,
— id: 4465, year: 2000, vol: , page: 577, stat: Chapter,

Enkephalin receptors and receptor-mediated signal transduction in cultured human lymphocytes
Heagy, W; Teng, E; Lopez, P; Finberg, R W
1999 Jan 10;191(1):34-48, Cellular immunology
— id: 73146, year: 1999, vol: 191, page: 34, stat: Journal Article,

Fluorescence-activated cell sorting of transfected cells
Adams, P D; Lopez, P; Sellers, W R; Kaelin, W G Jr
1997 ;283:59-72, Methods in enzymology
— id: 73145, year: 1997, vol: 283, page: 59, stat: Journal Article,

Biosafety guidelines for sorting of unfixed cells
Schmid, I; Nicholson, J K; Giorgi, J V; Janossy, G; Kunkl, A; Lopez, P A; Perfetto, S; Seamer, L C; Dean, P N
1997 Jun 1;28(2):99-117, Cytometry
— id: 73144, year: 1997, vol: 28, page: 99, stat: Journal Article,

Fas modulation of apoptosis during negative selection of thymocytes
Castro, J E; Listman, J A; Jacobson, B A; Wang, Y; Lopez, P A; Ju, S; Finn, P W; Perkins, D L
1996 Dec;5(6):617-627, Immunity
— id: 73143, year: 1996, vol: 5, page: 617, stat: Journal Article,

In situ fluorescence labeling of sheep lung microvascular endothelium
Abdi, K; Rogers, R A; Li, X; Lopez, P; Rawn, J; Mentzer, S J
1995 Apr;31(4):310-315, In vitro cellular & developmental biology. Animal
— id: 73142, year: 1995, vol: 31, page: 310, stat: Journal Article,

Functional isolation and characterization of human hematopoietic stem cells
Berardi, A C; Wang, A; Levine, J D; Lopez, P; Scadden, D T
1995 Jan 6;267(5194):104-108, Science
— id: 73141, year: 1995, vol: 267, page: 104, stat: Journal Article,

A simple fluorescence method for surface antigen phenotyping of lymphocytes undergoing DNA fragmentation
Hardin, J A; Sherr, D H; DeMaria, M; Lopez, P A
1992 Sep 18;154(1):99-107, Journal of immunological methods
— id: 73125, year: 1992, vol: 154, page: 99, stat: Journal Article,

A population of early fetal thymocytes expressing Fc gamma RII/III contains precursors of T lymphocytes and natural killer cells
Rodewald, H R; Moingeon, P; Lucich, J L; Dosiou, C; Lopez, P; Reinherz, E L
1992 Apr 3;69(1):139-150, Cell
— id: 73128, year: 1992, vol: 69, page: 139, stat: Journal Article,

Inhibition of immune functions by antiviral drugs
Heagy, W; Crumpacker, C; Lopez, P A; Finberg, R W
1991 Jun;87(6):1916-1924, Journal of clinical investigation
— id: 73133, year: 1991, vol: 87, page: 1916, stat: Journal Article,

Assembly and function of the T cell antigen receptor. Requirement of either the lysine or arginine residues in the transmembrane region of the alpha chain
Blumberg, R S; Alarcon, B; Sancho, J; McDermott, F V; Lopez, P; Breitmeyer, J; Terhorst, C
1990 Aug 15;265(23):14036-14043, Journal of biological chemistry
— id: 73135, year: 1990, vol: 265, page: 14036, stat: Journal Article,

Characterization of functional GTP binding proteins in Jurkat T cell mutants lacking either CD3-Ti or CD2 surface receptors
Moingeon, P; Jin, Y J; Stebbins, C C; Lopez, P A; Alcover, A; Reinherz, E L
1990 Jul;128(2):578-588, Cellular immunology
— id: 73134, year: 1990, vol: 128, page: 578, stat: Journal Article,

Dissection of the human CD2 intracellular domain. Identification of a segment required for signal transduction and interleukin 2 production
Chang, H C; Moingeon, P; Lopez, P; Krasnow, H; Stebbins, C; Reinherz, E L
1989 Jun 1;169(6):2073-2083, Journal of experimental medicine
— id: 73137, year: 1989, vol: 169, page: 2073, stat: Journal Article,

Phosphatidylinositl-anchored antigens defined by non-lineage mAb
Selvaraj P; Low MG; Lopez P; Springer TA
Leucocyte typing IV : white cell differentation antigens Oxford : Oxford University Press, 1989,
— id: 4464, year: 1989, vol: , page: 734, stat: Chapter,

Interdependence of CD3-Ti and CD2 activation pathways in human T lymphocytes
Alcover, A; Alberini, C; Acuto, O; Clayton, L K; Transy, C; Spagnoli, G C; Moingeon, P; Lopez, P; Reinherz, E L
1988 Jul;7(7):1973-1977, EMBO journal
— id: 73138, year: 1988, vol: 7, page: 1973, stat: Journal Article,

A protocol for Papanicolaou staining of cytologic specimens following flow analysis
Berkan, T K; Reeder, J E; Lopez, P A Jr; Gorman, K M; Wheeless, L L Jr
1986 Jan;7(1):101-103, Cytometry
— id: 73136, year: 1986, vol: 7, page: 101, stat: Journal Article,

Multidimensional slit-scan prescreening system: preliminary results of a single blind clinical study
Wheeless, L L; Patten, S F; Berkan, T K; Brooks, C L; Gorman, K M; Lesh, S R; Lopez, P A; Wood, J C
1984 Jan;5(1):1-8, Cytometry
— id: 73139, year: 1984, vol: 5, page: 1, stat: Journal Article,

Syringing as a method of cell dispersal. II. Effect on abnormal cells
Lopez, P A; Cambier, M A; Wheeless, L L Jr
1981 Sep;3(3):235-238, Analytical & quantitative cytology
— id: 73140, year: 1981, vol: 3, page: 235, stat: Journal Article,