Catherine G Klein

Biosketch / Results /

Catherine G Klein, Ph.D.

Assistant Professor;
Department of Environmental Medicine

Contact Info

Address
57 Old Forge Road
Floor 2 Room 204A
Sterling Forest
Tuxedo, NY 10987

845-731-3510
845-351-2058
Catherine.Klein@nyumc.org

« Back to Results

Education

1988 — Dr. Klein received her Ph.D. from New York University, Graduate Education

« Back to Results

Research Summary

With molecular biologic and molecular cytogenetic techniques, we study the mutagenic and epigenetic mechanisms that silence genes, including transgene expression in a unique set of mammalian cell lines. The G12 and G10 cell lines each contain a bacterial xanthine-guanine phosphoribosyl transferase (gpt) gene target that has been stably inserted into different chromosomal genome locations. These cell lines exhibit differing propensities for mutagenesis, deletions and epigenetic gene silencing by various oxidative carcinogens and clastogens, including x-rays, anticancer therapeutics, metals and traditionally nonmutagenic carcinogens such as diethylstilbestrol (DES). The assay offers the ability to analyze the epigenetic potential of other putative xenoestrogens or environmental toxicants, such as organic pesticides, environmental mixtures and nanoparticles. Using this assay system, the epigenetic silencing of the gpt transgene by DNA condensation, excess methylation and histone modifications were identified as important mechanisms for trangene silencing in carcinogenic nickel-induced G12 mutants. Epigenome arrays add complementary information about other genes and pathways that can be altered by a variety of environmental exposures.

Research Interests

Mechanisms of gene silencing, epigenetics, gene methylation, environmental toxicants, metals

Research Keywords

DNA methylation, epigenetics, metals, estrogens, transgene, xenoestrogens,

« Back to Results

All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Current and future prospectives for jobs in science
Klein, C B
2014 September 2014;55:S19-S19, Environmental & molecular mutagenesis
— id: 1291802, year: 2014, vol: 55, page: S19, stat: Journal Article,

Epigenetic assays: Updates, benefits, and limitations
Klein, C B
2014 September 2014;55:S27-S27, Environmental & molecular mutagenesis
— id: 1291792, year: 2014, vol: 55, page: S27, stat: Journal Article,

Building on the past, shaping the future: The environmental mutagenesis and genomics society
Wilson, Thomas E; Demarini, David M; Dertinger, Stephen D; Engelward, Bevin P; Hanawalt, Philip C; Macgregor, James T; Smith-Roe, Stephanie L; Witt, Kristine L; Yauk, Carole L; Ljungman, Mats; Schwartz, Jeffrey L; Klein, Catherine B
2013 Apr;54(3):153-157, Environmental & molecular mutagenesis
— id: 255582, year: 2013, vol: 54, page: 153, stat: Journal Article,

Harnessing genomics to identify environmental determinants of heritable disease
Yauk, Carole Lyn; Lucas Argueso, J; Auerbach, Scott S; Awadalla, Philip; Davis, Sean R; Demarini, David M; Douglas, George R; Dubrova, Yuri E; Elespuru, Rosalie K; Glover, Thomas W; Hales, Barbara F; Hurles, Matthew E; Klein, Catherine B; Lupski, James R; Manchester, David K; Marchetti, Francesco; Montpetit, Alexandre; Mulvihill, John J; Robaire, Bernard; Robbins, Wendie A; Rouleau, Guy A; Shaughnessy, Daniel T; Somers, Christopher M; Taylor, James G 6th; Trasler, Jacquetta; Waters, Michael D; Wilson, Thomas E; Witt, Kristine L; Bishop, Jack B
2013 Jan;752(1):6-9, Mutation research
— id: 218222, year: 2013, vol: 752, page: 6, stat: Journal Article,

A Historical Overview of Cell-Based Assays for Detecting Epigenetic Effects
Klein, C.
2012 SEP;53 1 1:S41-S41, Environmental & molecular mutagenesis
— id: 177763, year: 2012, vol: 53 1 1, page: S41, stat: Journal Article,

Impairment of antioxidant defenses as a contributor to arsenite-induced cell transformation
Wu, Jing; Sowinska, Anna; Huang, Xi; Klein, Catherine B; Pelle, Edward; Frenkel, Krystyna
2012 Oct;25(5):927-937, Biometals
— id: 177140, year: 2012, vol: 25, page: 927, stat: Journal Article,

Genetic and epigenetic effects of environmental arsenicals
Rossman, Toby G; Klein, Catherine B
2011 Nov 1;3(11):1135-1141, Metallomics : integrated biometal science
— id: 140528, year: 2011, vol: 3, page: 1135, stat: Journal Article,

Caffeic acid phenethyl ester (CAPE), derived from a honeybee product propolis, exhibits a diversity of anti-tumor effects in pre-clinical models of human breast cancer
Wu, Jing; Omene, Coral; Karkoszka, Jerzy; Bosland, Maarten; Eckard, Jonathan; Klein, Catherine B; Frenkel, Krystyna
2011 Sep 1;308(1):43-53, Cancer letters
— id: 134448, year: 2011, vol: 308, page: 43, stat: Journal Article,

DNA methylation in pre-diagnostic serum samples of breast cancer cases: Results of a nested case-control study
Brooks, Jennifer D; Cairns, Paul; Shore, Roy E; Klein, Catherine B; Wirgin, Isaac; Afanasyeva, Yelena; Zeleniuch-Jacquotte, Anne
2010 Dec;34(6):717-723, Cancer epidemiology
— id: 114817, year: 2010, vol: 34, page: 717, stat: Journal Article,

A genome-wide deletion mutant screen identifies pathways affected by nickel sulfate in Saccharomyces cerevisiae
Arita, Adriana; Zhou, Xue; Ellen, Thomas P; Liu, Xin; Bai, Jingxiang; Rooney, John P; Kurtz, Adrienne; Klein, Catherine B; Dai, Wei; Begley, Thomas J; Costa, Max
2009 ;10:524-524, BMC genomics
— id: 105506, year: 2009, vol: 10, page: 524, stat: Journal Article,

Persistence of Epigenetic Changes Induced by Chronic Submicromolar Arsenic
Klein, CB; Mauro, M
2009 AUG ;50(7):552-552, Environmental & molecular mutagenesis
— id: 101939, year: 2009, vol: 50, page: 552, stat: Journal Article,

A genome-wide screen in Saccharomyces cerevisiae reveals pathways affected by arsenic toxicity
Zhou, Xue; Arita, Adriana; Ellen, Thomas P; Liu, Xin; Bai, Jingxiang; Rooney, John P; Kurtz, Adrienne D; Klein, Catherine B; Dai, Wei; Begley, Thomas J; Costa, Max
2009 Nov;94(5):294-307, Genomics
— id: 104719, year: 2009, vol: 94, page: 294, stat: Journal Article,

Modulation of gene methylation by genistein or lycopene in breast cancer cells
King-Batoon, Audrey; Leszczynska, Joanna M; Klein, Catherine B
2008 Jan;49(1):36-45, Environmental & molecular mutagenesis
— id: 76766, year: 2008, vol: 49, page: 36, stat: Journal Article,

Long-term exposure to submicromolar arsenite induces chromosome instability via bypass of the spindle assembly checkpoint in mammalian cells
Mauro, M; Leszczynska, J; Barbata, G; Caradonna, F; Sciandrello, G; Rossman, TG; Klein, CB
2008 AUG ;49(7):548-548, Environmental & molecular mutagenesis
— id: 86808, year: 2008, vol: 49, page: 548, stat: Journal Article,

Mechanisms underlying prevention of genomic instability in breast tumor cells by Genistein and lycopene
Batoon, AK; Leszczynska, J; Klein, CB
2007 AUG ;48(7):618-618, Environmental & molecular mutagenesis
— id: 98041, year: 2007, vol: 48, page: 618, stat: Journal Article,

Nickel compounds
Cohen M; Klein C; Costa M
Environmental and occupational medicine Philadelphia : Wolters Kluwer/Lippincott Williams & Wilkins, 2007,
— id: 4440, year: 2007, vol: , page: ?, stat: Chapter,

Antimutagenicity of cinnamaldehyde and vanillin in human cells: Global gene expression and possible role of DNA damage and repair
King, Audrey A; Shaughnessy, Daniel T; Mure, Kanae; Leszczynska, Joanna; Ward, William O; Umbach, David M; Xu, Zongli; Ducharme, Danica; Taylor, Jack A; Demarini, David M; Klein, Catherine B
2007 Mar 1;616(1-2):60-69, Mutation research
— id: 71922, year: 2007, vol: 616, page: 60, stat: Journal Article,

Nickel
Klein CB; Costa M
Handbook on the toxicology of metals Burlington MA : Academic Press, 2007,
— id: 4437, year: 2007, vol: , page: 743, stat: Chapter,

Further evidence against a direct genotoxic mode of action for arsenic-induced cancer
Klein, Catherine B; Leszczynska, Joanna; Hickey, Christina; Rossman, Toby G
2007 Aug 1;222(3):289-297, Toxicology & applied pharmacology
— id: 72150, year: 2007, vol: 222, page: 289, stat: Journal Article,

Response to comments by post and stern on article "Toxicity and carcinogenicity of chromium compounds in humans"
Costa, M; Klein, C
2006 OCT ;36(9):779-779, Critical reviews in toxicology
— id: 68959, year: 2006, vol: 36, page: 779, stat: Journal Article,

Toxicity and carcinogenicity of chromium compounds in humans
Costa, Max; Klein, Catherine B
2006 Feb;36(2):155-163, Critical reviews in toxicology
— id: 64671, year: 2006, vol: 36, page: 155, stat: Journal Article,

Prevention of spontaneous and x-ray induced genomic instability in breast cancer cells by the dietary antimutagens genistein and lycopene
King, AA; Leszczynska, J; Hickey, CA; Klein, CB
2006 JUL ;47(6):425-425, Environmental & molecular mutagenesis
— id: 98062, year: 2006, vol: 47, page: 425, stat: Journal Article,

The genotoxic and epigenetic profile of arsenite and methylated metabolites in mammalian cells
Leszczynska, J; Hickey, C; Rossman, T; Klein, CB
2006 JUL ;47(6):470-470, Environmental & molecular mutagenesis
— id: 69546, year: 2006, vol: 47, page: 470, stat: Journal Article,

Modulation of gene methylation by genistein or lycopene in breast cells
Leszczynska, J; King, AA; Klein, CB
2006 JUL ;47(6):470-470, Environmental & molecular mutagenesis
— id: 69545, year: 2006, vol: 47, page: 470, stat: Journal Article,

Analysis of the ability of individual isoflavones in soybean-processing by-product mixtures to reduce spontaneous mutation in mismatch-repair deficient cells
Mure, K; Plewa, MJ; Takeshita, T; Rossman, TG; Klein, CB
2006 JUL ;47(6):461-461, Environmental & molecular mutagenesis
— id: 69544, year: 2006, vol: 47, page: 461, stat: Journal Article,

Arsenic, mode of action at biologically plausible low doses: What are the implications for low dose cancer risk?
Snow, Elizabeth T; Sykora, Peter; Durham, Troy R; Klein, Catherine B
2005 Sep 1;207(2S):557-564, Toxicology & applied pharmacology
— id: 72708, year: 2005, vol: 207, page: 557, stat: Journal Article,

Mechanisms of inhibition of X-ray-induced mutations in Chinese hamster G12 cells by antioxidants
Leszczynska, J; Lasano, S; Klein, CB
2004 NOV 15 ;44(3):212-212, Environmental & molecular mutagenesis
— id: 46884, year: 2004, vol: 44, page: 212, stat: Journal Article,

Effects of soybean processing by-product on spontaneous mutation in mismatch-repair deficient cells
Mure, K; Plewa, MJ; Takeshita, T; Rossman, TG; Klein, CB
2004 NOV 15 ;44(3):217-217, Environmental & molecular mutagenesis
— id: 46885, year: 2004, vol: 44, page: 217, stat: Journal Article,

Lycopene prevents spontaneous mutagenesis in mismatch repair deficient human cells by inhibiting insertions but leaving deletion mutations
Mure, K; Takeshita, T; Rossman, TG; Klein, CB
2004 NOV ;13(11):1875S-1875S, Cancer epidemiology biomarkers & prevention
— id: 50166, year: 2004, vol: 13, page: 1875S, stat: Journal Article,

Arsenic mode of action at biologically plausible low doses: What are the implications for low dose cancer risk?
Snow, ET; Sykora, P; Durham, TR; Klein, CB
2004 JUN 15 ;197(3):170-170, Toxicology & applied pharmacology
— id: 46526, year: 2004, vol: 197, page: 170, stat: Journal Article,

Can dietary antioxidants prevent deletion mutations?
Klein, CB; Mure, K; Leszczynska, J; Matz, J; King, A; Rossman, TG
2003 NOV ;12(11):1346S-1347S, Cancer epidemiology biomarkers & prevention
— id: 55378, year: 2003, vol: 12, page: 1346S, stat: Journal Article,

Lycopene prevents spontaneous mutagenesis in mismatch repair deficient human cells mainly by inhibiting point mutations
Mure, K; Takeshita, T; Rossman, TG; Klein, CB
2003 NOV ;12(11):1308S-1309S, Cancer epidemiology biomarkers & prevention
— id: 55374, year: 2003, vol: 12, page: 1308S, stat: Journal Article,

Chromate-induced epimutations in mammalian cells
Klein, Catherine B; Su, Lin; Bowser, Darlene; Leszczynska, Joanna
2002 Oct;110 Suppl 5(5):739-743, Environmental health perspectives
— id: 39564, year: 2002, vol: 110 Suppl 5, page: 739, stat: Journal Article,

Mutagenesis assays in Mammalian cells
Klein, C B; Broday, L; Costa, M
2001 May;Chapter 3:Unit3.3-Unit3.3, Current protocols in toxicology
— id: 113815, year: 2001, vol: Chapter 3, page: Unit3.3, stat: Journal Article,

Synergism in nitric oxide and hydrogen peroxide induced mutagenesis in G12 Chinese hamster cells
Abu-Shakra, A; Klein, CB
1999 DEC ;27(4):S71-S71, Free radical biology & medicine
— id: 53794, year: 1999, vol: 27, page: S71, stat: Journal Article,

Nickel carcinogenesis, mutation, epigenetics, or selection
Costa, M; Klein, CB
1999 SEP ;107(9):A438-A439, Environmental health perspectives
— id: 53956, year: 1999, vol: 107, page: A438, stat: Journal Article,

DNA methylation and gene expression: introduction and overview
Klein CB; Costa M
1997 Apr;386(2):103-105, Mutation research
— id: 12337, year: 1997, vol: 386, page: 103, stat: Journal Article,

DNA methylation, heterochromatin and epigenetic carcinogens
Klein CB; Costa M
1997 Apr;386(2):163-180, Mutation research
— id: 8210, year: 1997, vol: 386, page: 163, stat: Journal Article,

Characterization of gpt deletion mutations in transgenic Chinese hamster cell lines
Klein CB; Su L; Singh J; Snow ET
1997 ;30(4):418-428, Environmental & molecular mutagenesis
— id: 57177, year: 1997, vol: 30, page: 418, stat: Journal Article,

Mutagenicity of cobalt and reactive oxygen producers
Kitahara J; Yamanaka K; Kato K; Lee YW; Klein CB; Costa M
1996 Oct 1;370(3-4):133-140, Mutation research
— id: 10369, year: 1996, vol: 370, page: 133, stat: Journal Article,

Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens
Lee YW; Klein CB; Kargacin B; Salnikow K; Kitahara J; Dowjat K; Zhitkovich A; Christie NT; Costa M
1995 May;15(5):2547-2557, Molecular & cellular biology
— id: 6675, year: 1995, vol: 15, page: 2547, stat: Journal Article,

Molecular mechanisms of nickel carcinogenesis
Costa M; Salnikow K; Cosentino S; Klein CB; Huang X; Zhuang Z
1994 Sep;102 Suppl 3:127-130, Environmental health perspectives
— id: 8073, year: 1994, vol: 102 Suppl 3, page: 127, stat: Journal Article,

Molecular mechanisms of nickel carcinogenesis
Costa M; Zhuang Z; Huang X; Cosentino S; Klein CB; Salnikow K
1994 Jun 6;148(2-3):191-199, Science of the total environment
— id: 10380, year: 1994, vol: 148, page: 191, stat: Journal Article,

2ND INTERNATIONAL MEETING ON MOLECULAR MECHANISMS OF METAL TOXICITY AND CARCINOGENICITY - JANUARY 10-17, 1993 MADONNA-DI-CAMPIGLIO, ITALY - PREFACE
COSTA, M; CANTONI, O; KLEIN, C; ROSSMAN, T; SNOW, E; SUK, W
1994 SEP ;102(1):2-2, Environmental health perspectives
— id: 52335, year: 1994, vol: 102, page: 2, stat: Journal Article,

Crystalline Ni3S2 specifically enhances the formation of oxidants in the nuclei of CHO cells as detected by dichlorofluorescein
Huang X; Klein CB; Costa M
1994 Mar;15(3):545-548, Carcinogenesis
— id: 6409, year: 1994, vol: 15, page: 545, stat: Journal Article,

The role of nickel and nickel-mediated reactive oxygen species in the mechanism of nickel carcinogenesis
Huang X; Zhuang Z; Frenkel K; Klein CB; Costa M
1994 Sep;102 Suppl 3:281-284, Environmental health perspectives
— id: 6647, year: 1994, vol: 102 Suppl 3, page: 281, stat: Journal Article,

Metal mutagenesis in transgenic Chinese hamster cell lines
Klein CB; Kargacin B; Su L; Cosentino S; Snow ET; Costa M
1994 Sep;102 Suppl 3:63-67, Environmental health perspectives
— id: 6661, year: 1994, vol: 102 Suppl 3, page: 63, stat: Journal Article,

Transgenic gpt+ V79 cell lines differ in their mutagenic response to clastogens
Klein CB; Su L; Rossman TG; Snow ET
1994 Jan 16;304(2):217-228, Mutation research
— id: 6423, year: 1994, vol: 304, page: 217, stat: Journal Article,

Loss of thrombospondin transcriptional activity in nickel-transformed cells
Salnikow K; Cosentino S; Klein C; Costa M
1994 Jan;14(1):851-858, Molecular & cellular biology
— id: 6507, year: 1994, vol: 14, page: 851, stat: Journal Article,

The loss of thrombospondin expression in Ni-resistant and Ni-transformed cells
Salnikow K; Wang S; Gao M; Klein C; Costa M
1994 ;35:A1122-A1122, Proceedings of the annual meeting of the American Association for Cancer Research
— id: 6019, year: 1994, vol: 35, page: A1122, stat: Journal Article,

Mechanisms of chromium carcinogenicity and toxicity
Cohen MD; Kargacin B; Klein CB; Costa M
1993 ;23(3):255-281, Critical reviews in toxicology
— id: 6337, year: 1993, vol: 23, page: 255, stat: Journal Article,

Methods used for analyses of "environmentally" damaged nucleic acids
Frenkel K; Klein CB
1993 Aug 25;618(1-2):289-314, Journal of chromatography
— id: 6373, year: 1993, vol: 618, page: 289, stat: Journal Article,

METHODS USED FOR ANALYSES OF ENVIRONMENTALLY DAMAGED NUCLEIC-ACIDS
FRENKEL, K; KLEIN, CB
1993 AUG 25 ;618(1-2):289-314, Journal of chromatography. Pt. B. Biomedical applications
— id: 52242, year: 1993, vol: 618, page: 289, stat: Journal Article,

Nickel induces increased oxidants in intact cultured mammalian cells as detected by dichlorofluorescein fluorescence
Huang X; Frenkel K; Klein CB; Costa M
1993 May;120(1):29-36, Toxicology & applied pharmacology
— id: 10384, year: 1993, vol: 120, page: 29, stat: Journal Article,

Mutagenic responses of nickel oxides and nickel sulfides in Chinese hamster V79 cell lines at the xanthine-guanine phosphoribosyl transferase locus
Kargacin B; Klein CB; Costa M
1993 Jun;300(1):63-72, Mutation research
— id: 10383, year: 1993, vol: 300, page: 63, stat: Journal Article,

Mutagenicity of soluble and insoluble nickel compounds at the gpt locus in G12 Chinese hamster cells
Lee YW; Pons C; Tummolo DM; Klein CB; Rossman TG; Christie NT
1993 ;21(4):365-371, Environmental & molecular mutagenesis
— id: 13287, year: 1993, vol: 21, page: 365, stat: Journal Article,

The role of Ni(II) in mutation
Christie NT; Tummolo DM; Klein CB; Rossman TG
Nickel and human health : current perspectives New York : Wiley, 1992,
— id: 4396, year: 1992, vol: , page: 305, stat: Chapter,

Forward mutations and DNA-protein crosslinks induced by ammonium metavanadate in cultured mammalian cells
Cohen MD; Klein CB; Costa M
1992 Sep;269(1):141-148, Mutation research
— id: 13468, year: 1992, vol: 269, page: 141, stat: Journal Article,

A conserved region in human and Chinese hamster X chromosomes can induce cellular senescence of nickel-transformed Chinese hamster cell lines
Wang XW; Lin X; Klein CB; Bhamra RK; Lee YW; Costa M
1992 Apr;13(4):555-561, Carcinogenesis
— id: 13643, year: 1992, vol: 13, page: 555, stat: Journal Article,

Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control
Klein CB; Conway K; Wang XW; Bhamra RK; Lin XH; Cohen MD; Annab L; Barrett JC; Costa M
1991 Feb 15;251(4995):796-799, Science
— id: 8211, year: 1991, vol: 251, page: 796, stat: Journal Article,

The role of oxidative processes in metal carcinogenesis
Klein CB; Frenkel K; Costa M
1991 Nov-Dec;4(6):592-604, Chemical research in toxicology
— id: 13852, year: 1991, vol: 4, page: 592, stat: Journal Article,

Performance of 133 compounds in the lambda prophage induction endpoint of the Microscreen assay and a comparison with S. typhimurium mutagenicity and rodent carcinogenicity assays
Rossman TG; Molina M; Meyer L; Boone P; Klein CB; Wang Z; Li F; Lin WC; Kinney PL
1991 Aug;260(4):349-367, Mutation research
— id: 13955, year: 1991, vol: 260, page: 349, stat: Journal Article,

Transgenic Chinese hamster V79 cell lines which exhibit variable levels of gpt mutagenesis
Klein, C B; Rossman, T G
1990 ;16(1):1-12, Environmental & molecular mutagenesis
— id: 132703, year: 1990, vol: 16, page: 1, stat: Journal Article,

Mutagenic metabolites of benzene detected in the Microscreen assay
Rossman RG; Klein CB; Snyder CA
1989 May;81:77-79, Environmental health perspectives
— id: 10646, year: 1989, vol: 81, page: 77, stat: Journal Article,

From DNA damage to mutation in mammalian cells: a review
Rossman TG; Klein CB
1988 ;11(1):119-133, Environmental & molecular mutagenesis
— id: 11233, year: 1988, vol: 11, page: 119, stat: Journal Article,

IDENTIFICATION OF A HIGHLY MUTAGENIC METABOLITE OF BENZENE
Rossman, TG; Klein, CB; Snyder, CA
1988 Mar;29(5):124-124, Proceedings (American Association for Cancer Research)
— id: 31481, year: 1988, vol: 29, page: 124, stat: Journal Article,

Comutagens in E. coli and Chinese hampster cells with special attention to arsenite
Rossman TG; Molina M; Klein CB
Genetic toxicology of environmental chemicals. Pt. A New York : A.R. Liss, 1986,
— id: 4399, year: 1986, vol: , page: 403, stat: Chapter,

ASCORBATE ENHANCES UV-MUTAGENESIS IN ESCHERICHIA-COLI BUT INHIBITS IT IN CHINESE-HAMSTER CELLS
ROSSMAN, TG; KLEIN, CB; NASLUND, M
1986 MAY ;7(5):727-732, Carcinogenesis
— id: 41599, year: 1986, vol: 7, page: 727, stat: Journal Article,

MAMMALIAN SOS SYSTEM - A CASE OF MISPLACED ANALOGIES
Rossman, TG; Klein, CB
1985 ;3(2):175-187, Cancer investigation
— id: 30739, year: 1985, vol: 3, page: 175, stat: Journal Article,

BASE PAIR SUBSTITUTION AND FRAMESHIFT REVERTIBLE V79 CELL-LINES
Rossman, TG; Klein, CB; Stonewolff, DS
1985 ;7(1):7-7, Environmental mutagenesis
— id: 30880, year: 1985, vol: 7, page: 7, stat: Journal Article,

HGPRT- mutants of V79 cells that revert specifically by base pair substitution and frameshift mutations
Stone-Wolff, D S; Klein, C B; Rossman, T G
1985 ;7(3):281-291, Environmental mutagenesis
— id: 411622, year: 1985, vol: 7, page: 281, stat: Journal Article,

MUTAGENIC SPECIFICITY OF BETA-PROPIOLACTONE IN BACTERIA AND CHINESE-HAMSTER V79-CELLS
KLEIN, CB; ROSSMAN, TG
1984 ;6(3):426-426, Environmental mutagenesis
— id: 40938, year: 1984, vol: 6, page: 426, stat: Journal Article,