Biosketch / Results /

Joseph B Guttenplan, Ph.D.

Research Associate Professor;
Departments of Environmental Medicine and Basic Sciences

Contact Info

Address
345 E 24th St
9436 Room 1040S
Dental School
New York, NY 10010

212-998-9604
212-998-4087
Joseph.Guttenplan@nyumc.org

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

p53 Modulates Hsp90 ATPase Activity and Regulates Aryl Hydrocarbon Receptor Signaling
Kochhar, Amit; Kopelovich, Levy; Sue, Erika; Guttenplan, Joseph B; Herbert, Brittney-Shea; Dannenberg, Andrew J; Subbaramaiah, Kotha
2014 Jun;7(6):596-606, Cancer prevention research (Philadelphia, Pa.)
— id: 1067322, year: 2014, vol: 7, page: 596, stat: Journal Article,

Mutagenicity of furan in female Big Blue B6C3F1 mice
Terrell, Ashley N; Huynh, Mailee; Grill, Alex E; Kovi, Ramesh C; O'Sullivan, M Gerard; Guttenplan, Joseph B; Ho, Yen-Yi; Peterson, Lisa A
2014 Aug;770C:46-54, Mutation research: genetic toxicology & environmental mutagenesis
— id: 1315012, year: 2014, vol: 770C, page: 46, stat: Journal Article,

Comparison of the Xk and Pig-a genes as markers for mutations in red cells from mice
Araten, David J.; Halverson, Gregory; Zamechek, Leah; Csehak, Ken; Kosinska, Wieslawa; Guttenplan, Joseph
2013 APR 15;73(8 1 1):-, Cancer research
— id: 852602, year: 2013, vol: 73, page: , stat: Journal Article,

Mechanisms of oral carcinogenesis induced by dibenzo[a,l]pyrene: An environmental pollutant and a tobacco smoke constituent
Chen, Kun-Ming; Guttenplan, Joseph B; Zhang, Shang-Min; Aliaga, Cesar; Cooper, Timothy K; Sun, Yuan-Wan; Deltondo, Joseph; Kosinska, Wieslawa; Sharma, Arun K; Jiang, Kun; Bruggeman, Richard; Ahn, Kwangmi; Amin, Shantu; El-Bayoumy, Karam
2013 Sep;133(6):1300-1309, International journal of cancer
— id: 470562, year: 2013, vol: 133, page: 1300, stat: Journal Article,

Mechanisms underlying the varied mammary carcinogenicity of the environmental pollutant 6-nitrochrysene and its metabolites (-)-[R,R]- and (+)-[S,S]-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene in the rat
Sun, Yuan-Wan; Guttenplan, Joseph B; Cooper, Timothy; Krzeminski, Jacek; Aliaga, Ceaser; Boyiri, Telih; Kosinska, Wieslawa; Zhao, Zhong-Lin; Chen, Kun-Ming; Berg, Arthur; Amin, Shantu; El-Bayoumy, Karam
2013 Apr;26(4):547-554, Chemical research in toxicology
— id: 852612, year: 2013, vol: 26, page: 547, stat: Journal Article,

Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer
Guttenplan, JB; Kosinska, W; Zhao, ZL; Chen, KM; Aliaga, C; Deltondo, J; Cooper, T; Sun, YW; Zhang, SM; Jiang, K; Bruggeman, R; Sharma, AK; Amin, S; Ahn, K; El-Bayoumy, K
2012 Aug;:2783-2790, International journal of cancer
— id: 156493, year: 2012, vol: , page: 2783, stat: Journal Article,

Tissue-specific mutagenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine as the basis for urothelial carcinogenesis
He, Zhiming; Kosinska, Wieslawa; Zhao, Zhong-Lin; Wu, Xue-Ru; Guttenplan, Joseph B
2012 Feb;742(1-2):92-95, Mutation research
— id: 156491, year: 2012, vol: 742, page: 92, stat: Journal Article,

Carnosol, a Constituent of Zyflamend, Inhibits Aryl Hydrocarbon Receptor-Mediated Activation of CYP1A1 and CYP1B1 Transcription and Mutagenesis
Mohebati, Arash; Guttenplan, Joseph B; Kochhar, Amit; Zhao, Zhong-Lin; Kosinska, Wieslawa; Subbaramaiah, Kotha; Dannenberg, Andrew J
2012 Apr;5(4):593-602, Cancer prevention research (Philadelphia, Pa.)
— id: 166021, year: 2012, vol: 5, page: 593, stat: Journal Article,

Organ, species and sex differences in mutagenesis induced by butyl-hydroxybutyl-N-nitrosamine in big blue transgenic rodents as the basis for the strict organ specificity of this environmental carcinogen metabolite
He, Z; Strasberg-Rieber, Z -L Z; Kosinska, W; Wu, X -R; Guttenplan, J B
2011 15 Apr 2011;71(8):-, Cancer research
— id: 162905, year: 2011, vol: 71, page: , stat: Journal Article,

Effects of potential dietary inhibitors of endogenous DNA damage on mutagenesis and lipid peroxidation in lacZ mice
Kosinska, Wieslawa; Khmelnitsky, Michael; Kim, Jung Hyun; Zhao, Zhong-Lin; Guttenplan, Joseph B
2011 Jul;52(6):502-509, Environmental & molecular mutagenesis
— id: 156312, year: 2011, vol: 52, page: 502, stat: Journal Article,

Dimethylbenzanthracene (DMBA) and DMBA dihydrodiol mutagenicity in rat epithelial and fibroblast cell lines, and its inhibition by combinations of nutraceuticals
Sacks, P G; Zhao, Z -L; Kosinska, W; He, Z; Josephy, P D; Guttenplan, J B
2011 15 Apr 2011;71(8):-, Cancer research
— id: 162906, year: 2011, vol: 71, page: , stat: Journal Article,

Concentration dependent effects of tobacco particulates from different types of cigarettes on expression of drug metabolizing proteins, and benzo(a)pyrene metabolism in primary normal human oral epithelial cells
Sacks, Peter G; Zhao, Zhong-Lin; Kosinska, Wieslawa; Fleisher, Kenneth E; Gordon, Terry; Guttenplan, Joseph B
2011 Sep;49(9):2348-2355, Food & chemical toxicology
— id: 156326, year: 2011, vol: 49, page: 2348, stat: Journal Article,

The fjord region (+)-anti-dibenzo[a,l]pyrene-11,12-dihydrodiol-13,14-epoxides ((+)-anti-
Chen, K -M; Guttenplan, J B; Aliaga, C; Cooper, T; Deltondo, J; Kosinska, W; Sharma, A K; Sun, Y -W; Zhang, S; Jiang, K; Bruggeman, R; Amin, S; El-Bayoumy, K
2010 15 Apr 2010;70(8):-, Cancer research
— id: 1031622, year: 2010, vol: 70, page: , stat: Journal Article,

Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: A potential new model for oral cancer
Guttenplan, J B; Kosinska, W; Zhao, Z -L; Chen, K -M; Aliaga, C; Cooper, T; Sun, Y -W; Zhang, S; Jiang, K; Bruggeman, R; Sharma, A K; Amin, S; El-Bayoumy, K
2010 15 Apr 2010;70(8):-, Cancer research
— id: 1031612, year: 2010, vol: 70, page: , stat: Journal Article,

Effects of non-toxic agents and their combinations on genotoxicity-related endpoints, and mutagenesis induced by dimethylbenzanthracene-dihydrodiol in cultured rat mammary cells
Sacks, P G; Zhao, Z -L; Kosinska, W; He, Z; Vucetic, Z; Ngai, A; Guttenplan, J B
2010 15 Apr 2010;70(8):-, Cancer research
— id: 1031632, year: 2010, vol: 70, page: , stat: Journal Article,

Comparative Mutational Profiles of the Environmental Mammary Carcinogen 6-Nitrochrysene and Its [R,R]- and [S,S]-trans-1,2-Dihydroxy-1,2-dihydro-6-nitrochrysene Metabolites in a lac1 Mammary Epithelial Cell Line
Sun, YW; Guttenplan, JB; Kosinska, W; Krzeminski, J; Amin, S; El-Bayoumy, K
2010 ;23(1):277-277 JAN, Chemical research in toxicology
— id: 155009, year: 2010, vol: 23, page: 277, stat: Journal Article,

Modulations of benzo[a]pyrene-induced DNA adduct, cyclin D1 and PCNA in oral tissue by 1,4-phenylenebis(methylene)selenocyanate
Chen, Kun-Ming; Sacks, Peter G; Spratt, Thomas E; Lin, Jyh-Ming; Boyiri, Telih; Schwartz, Joel; Richie, John P; Calcagnotto, Ana; Das, Arunangshu; Bortner, James; Zhao, Zonglin; Amin, Shantu; Guttenplan, Joseph; El-Bayoumy, Karam
2009 May;383(1):151-155, Biochemical & biophysical research communications
— id: 160657, year: 2009, vol: 383, page: 151, stat: Journal Article,

UVR exposure sensitizes keratinocytes to DNA adduct formation
Nair, Sudhir; Kekatpure, Vikram D; Judson, Benjamin L; Rifkind, Arleen B; Granstein, Richard D; Boyle, Jay O; Subbaramaiah, Kotha; Guttenplan, Joseph B; Dannenberg, Andrew J
2009 Oct;2(10):895-902, Cancer prevention research (Philadelphia, Pa.)
— id: 156494, year: 2009, vol: 2, page: 895, stat: Journal Article,

Estrogen mediation of breast tumor formation involves estrogen receptor-dependent, as well as independent, genotoxic effects
Santen, Richard; Cavalieri, Ercole; Rogan, Eleanor; Russo, Jose; Guttenplan, Joseph; Ingle, James; Yue, Wei
2009 Feb;1155:132-140, Annals of the New York Academy of Sciences
— id: 135234, year: 2009, vol: 1155, page: 132, stat: Journal Article,

Stereoselective metabolism of the environmental mammary carcinogen 6-nitrochrysene to trans-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene by aroclor 1254-treated rat liver microsomes and their comparative mutation profiles in a laci mammary epithelial cell line
Sun, Yuan-Wan; Guttenplan, Joseph B; Khmelnitsky, Michael; Krzeminski, Jacek; Boyiri, Telih; Amin, Shantu; El-Bayoumy, Karam
2009 Dec;22(12):1992-1997, Chemical research in toxicology
— id: 156170, year: 2009, vol: 22, page: 1992, stat: Journal Article,

Heat shock protein 90 inhibitors suppress aryl hydrocarbon receptor-mediated activation of CYP1A1 and CYP1B1 transcription and DNA adduct formation
Hughes, Duncan; Guttenplan, Joseph B; Marcus, Craig B; Subbaramaiah, Kotha; Dannenberg, Andrew J
2008 Nov;1(6):485-493, Cancer prevention research (Philadelphia, Pa.)
— id: 156974, year: 2008, vol: 1, page: 485, stat: Journal Article,

Comparative mutational profiles of the environmental mammary carcinogen, 6-nitrochrysene and its metabolites in a lacI mammary epithelial cell line
Guttenplan, Joseph B; Zhao, Zhong-lin; Kosinska, Wieslawa; Norman, Robert G; Krzeminski, Jacek; Sun, Yuan-Wan; Amin, Shantu; El-Bayoumy, Karam
2007 Nov;28(11):2391-2397, Carcinogenesis
— id: 156975, year: 2007, vol: 28, page: 2391, stat: Journal Article,

Effects of 1,4-phenylenebis(methylene)selenocyanate on mutagenesis and p53 protein expression in the tongue of lacI rats treated with 4-nitroquinoline-N-oxide
Guttenplan, Joseph; Chen, Kun-Ming; Khmelnitsky, Michael; Kosinska, Wieslawa; Hennessy, Jeannie; Bruggeman, Richard; Desai, Dhimant; Amin, Shantu; Sun, Yuan-Wan; Spratt, Tomas E; El-Bayoumy, Karam
2007 Dec 1;634(1-2):146-155, Mutation research
— id: 111782, year: 2007, vol: 634, page: 146, stat: Journal Article,

Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention
Cavalieri, Ercole; Chakravarti, Dhubajyoti; Guttenplan, Joseph; Hart, Elizabeth; Ingle, James; Jankowiak, Ryszard; Muti, Paola; Rogan, Eleanor; Russo, Jose; Santen, Richard; Sutter, Thomas
2006 Aug;1766(1):63-78, Biochimica & biophysica acta
— id: 156970, year: 2006, vol: 1766, page: 63, stat: Journal Article,

Mutagenic activity of 4-hydroxyestradiol, but not 2-hydroxyestradiol, in BB rat2 embryonic cells, and the mutational spectrum of 4-hydroxyestradiol
Zhao, Zhonglin; Kosinska, Wieslawa; Khmelnitsky, Michael; Cavalieri, Ercole L; Rogan, Eleanor G; Chakravarti, Dhrubajyoti; Sacks, Peter G; Guttenplan, Joseph B
2006 Mar;19(3):475-479, Chemical research in toxicology
— id: 156639, year: 2006, vol: 19, page: 475, stat: Journal Article,

Mammary carcinogenesis and molecular analysis of in vivo cII gene mutations in the mammary tissue of female transgenic rats treated with the environmental pollutant 6-nitrochrysene
Boyiri, Telih; Guttenplan, Joseph; Khmelnitsky, Michael; Kosinska, Wieslawa; Lin, Jyh-Ming; Desai, Dhimant; Amin, Shantu; Pittman, Brian; El-Bayoumy, Karam
2004 Apr;25(4):637-643, Carcinogenesis
— id: 156969, year: 2004, vol: 25, page: 637, stat: Journal Article,

Mutational spectrum of bleomycin in lacZ mouse kidney: a possible model for mutational spectrum of reactive oxygen species
Guttenplan, Joseph B; Khmelnitsky, Michael; Haesevoets, Roderick; Kosinska, Wieslawa
2004 Oct;554(1-2):185-192, Mutation research
— id: 156545, year: 2004, vol: 554, page: 185, stat: Journal Article,

Effects of 3H-1,2-dithiole-3-thione, 1,4-phenylenebis(methylene)selenocyanate, and selenium-enriched yeast individually and in combination on benzo[a]pyrene-induced mutagenesis in oral tissue and esophagus in lacZ mice
Guttenplan, Joseph B; Spratt, Thomas E; Khmelnitsky, Michael; Kosinska, Wieslawa; Desai, Dhimant; El-Bayoumy, Karam
2004 Apr;559(1-2):199-210, Mutation research
— id: 156546, year: 2004, vol: 559, page: 199, stat: Journal Article,

Mutational specificity of N-nitrosonornicotine in lacZ mice: Mutations at A : T base pairs
Kosinska, W; Khmelnitsky, M; Cote, M; Guttenplan, JG
2004 ;44(3):97-1396 OCT, Environmental & molecular mutagenesis
— id: 154417, year: 2004, vol: 44, page: 97, stat: Journal Article,

Comparative mutagenicities of bleomycin and ferric-nitrilotriacetate in lacZ mice (vol 187, pg 41, 2002)
Kosinska, W; Pelle, E; von Pressentin, MD; Chen, M; Guttenplan, JB
2004 MAR 18 ;205(2):229-229, Cancer letters
— id: 42558, year: 2004, vol: 205, page: 229, stat: Journal Article,

Effects of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and vitamin E on 4-nitroquinoline-N-oxide (4-NQO)-induced mutagenesis in lacZ mouse upper aerodigestive tissue (vol 518, pg 85, 2002)
Guttenplan, JB; Kosinska, W; von Pressentin, MD; Rosa, J; El-Bayoumy, K
2002 ;521(1-2):209-209 NOV 26, Mutation research: genetic toxicology & environmental mutagenesis
— id: 153623, year: 2002, vol: 521, page: 209, stat: Journal Article,

(Correction of Previews 200200417076. Effects of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and vitamin E on 4-nitroquinoline-N-oxide (4-NQO)-induced mutagenesis in lacZ mouse upper aerodigestive tissue. Correction of abstract.)
Guttenplan, Joseph B.; Kosinska, Wieslava; von Pressentin, Marcia d.M.; Rosa, Jose; El-Bayoumy, Karam
2002 ;521(1-2):561-566 26 November,, Mutation research
— id: 154273, year: 2002, vol: 521, page: 561, stat: Journal Article,

Effects of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and vitamin E on 4-nitroquinoline-N-oxide (4-NQO)-induced mutagenesis in lacZ mouse upper aerodigestive tissue
Guttenplan, Joseph B; Kosinska, Wieslava; von Pressentin, Marcia d M; Rosa, Jose; El-Bayoumy, Karam
2002 Jun;518(1):85-93, Mutation research
— id: 156595, year: 2002, vol: 518, page: 85, stat: Journal Article,

Comparative mutagenicities of bleomycin and ferric-nitrilotriacetate in lacZ mice
Kosinska, Wieslawa; Pelle, Edward; von Pressentin, Marcia d M; Chen, Michael; Guttenplan, Joseph B
2002 Dec;187(1-2):41-46, Cancer letters
— id: 156976, year: 2002, vol: 187, page: 41, stat: Journal Article,

Effects of a lycopene-rich diet on spontaneous and benzo[a]pyrene-induced mutagenesis in prostate, colon and lungs of the lacZ mouse
Guttenplan, J B; Chen, M; Kosinska, W; Thompson, S; Zhao, Z; Cohen, L A
2001 Mar;164(1):1-6, Cancer letters
— id: 156596, year: 2001, vol: 164, page: 1, stat: Journal Article,

Mutagenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-4-(methylnitrosamino)-1-(3-pyridyl )-1-butanone and N-nitrosonornicotine in lacZ upper aerodigestive tissue and liver and inhibition by green tea
von Pressentin , M M; Chen, M; Guttenplan, J B
2001 Jan;22(1):203-206, Carcinogenesis
— id: 156597, year: 2001, vol: 22, page: 203, stat: Journal Article,

Mutagenic activity of 4-nitroquinoline-N-oxide in upper aerodigestive tissue in lacZ mice (MutaMouse) and the effects of 1, 4-phenylenebis(methylene)selenocyanate
von Pressentin, M M; El-Bayoumy, K; Guttenplan, J B
2000 Mar;466(1):71-78, Mutation research
— id: 156598, year: 2000, vol: 466, page: 71, stat: Journal Article,

Inhibition of NNK-induced mutagenesis in lacZ mouse oral tissue
Von Pressentin, MM; Kosinska, W; Guttenplan, JB
2000 FEB ;79(1):252-252, Journal of dental research
— id: 54746, year: 2000, vol: 79, page: 252, stat: Journal Article,

Mutagenesis induced by benzo[a]pyrene in lacZ mouse mammary and oral tissues: comparisons with mutagenesis in other organs and relationships to previous carcinogenicity assays
Kosinska, W; von Pressentin, M D; Guttenplan, J B
1999 Jun;20(6):1103-1106, Carcinogenesis
— id: 156599, year: 1999, vol: 20, page: 1103, stat: Journal Article,

Mutagenesis induced by oral carcinogens in lacZ mouse (MutaMouse) tongue and other oral tissues
von Pressentin MM; Kosinska W; Guttenplan JB
1999 Nov;20(11):2167-2170, Carcinogenesis
— id: 11936, year: 1999, vol: 20, page: 2167, stat: Journal Article,

Progression of hepatic neoplasms is severely retarded in mice lacking the, bisecting N-acetylglucosamine on N-glycans: Evidence for a glycoprotein factor that facilitates hepatic tumor progression
Bhaumik, M; Harris, T; Sundaram, S; Johnson, L; Guttenplan, J; Rogler, C; Stanley, P
1998 ;58(13):2881-2887 JUL 1, Cancer research
— id: 154329, year: 1998, vol: 58, page: 2881, stat: Journal Article,

Levels of O-6-methylguanine DNA repair activity in human gingival tissue
Hussain, SI; Guttenplan, JB
1998 MAY ;77(3):767-767, Journal of dental research
— id: 53451, year: 1998, vol: 77, page: 767, stat: Journal Article,

1,N2-propanodeoxyguanosine adducts: potential new biomarkers of smoking-induced DNA damage in human oral tissue
Nath, R G; Ocando, J E; Guttenplan, J B; Chung, F L
1998 Feb;58(4):581-584, Cancer research
— id: 156600, year: 1998, vol: 58, page: 581, stat: Journal Article,

Mutagenesis induced by carcinogens in the mouse oral cavity
Haghighi, K; Guttenplan, J
1997 JAN ;76(1):3473-3473, Journal of dental research
— id: 91283, year: 1997, vol: 76, page: 3473, stat: Journal Article,

Unexpected genetic toxicity to rodents of the N',N'-dimethyl analogues of MNU and ENU
Tinwell, H; Paton, D; Guttenplan, J B; Ashby, J
1996 ;27(3):202-210, Environmental & molecular mutagenesis
— id: 156601, year: 1996, vol: 27, page: 202, stat: Journal Article,

Biochemistry
Guttenplan, Joseph B.; Oratz, Murray
New York : Sulzberger & Graham Publishing, Ltd., [c1994],
— id: 547, year: 1994, vol: , page: , stat: ,

2,3-epoxy-4-hydroxynonanal as a potential tumor-initiating agent of lipid peroxidation
Chung, F L; Chen, H J; Guttenplan, J B; Nishikawa, A; Hard, G C
1993 Oct;14(10):2073-2077, Carcinogenesis
— id: 156602, year: 1993, vol: 14, page: 2073, stat: Journal Article,

Effects of cytosol on mutagenesis induced by N-nitrosodimethylamine, N-nitrosomethylurea and alpha-acetoxy-N-nitrosodimethylamine in different strains of Salmonella: evidence for different ultimate mutagens from N-nitrosodimethylamine
Guttenplan, J B
1993 May;14(5):1013-1019, Carcinogenesis
— id: 156604, year: 1993, vol: 14, page: 1013, stat: Journal Article,

High mutagenic activity of N-nitrosobis(2-oxopropyl)amine and N-nitrosobis(2-hydroxypropyl)amine in the host-mediated assay in hamsters: evidence for premutagenic methyl and hydroxylpropyl adducts
Guttenplan, J B; Kokkinakis, D
1993 Aug;14(8):1621-1625, Carcinogenesis
— id: 156603, year: 1993, vol: 14, page: 1621, stat: Journal Article,

Mutational specificities of environmental carcinogens in the lac1 gene of Escherichia coli, VII: The host-mediated assay and its comparison with in vitro mutagenesis induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
Jiao, J; Guttenplan, J B; Glickman, B W; Anderson, M W; Xin, L Y; Zielenska, M
1993 ;8(3):127-131, Molecular carcinogenesis
— id: 156605, year: 1993, vol: 8, page: 127, stat: Journal Article,

Mutational specificities of N-nitrosamines in a host-mediated assay: comparison with direct-acting N-nitroso compounds in vitro and an approach to deducing the nature of ultimate mutagens in vivo
Liu, Y X; Guttenplan, J B
1992 ;6(4):232-237, Molecular carcinogenesis
— id: 156606, year: 1992, vol: 6, page: 232, stat: Journal Article,

MECHANISMS OF CARCINOGENESIS AND MUTAGENESIS BY N-NITROSAMINES
GUTTENPLAN, JB
1991 AUG 25 ;202(3):10-CHAS, Abstracts of papers (American Chemical Society)
— id: 52078, year: 1991, vol: 202, page: 10, stat: Journal Article,

Mutagenesis by N-nitroso compounds: relationships to DNA adducts, DNA repair, and mutational efficiencies
Guttenplan, J B
1990 Nov-Dec;233(1-2):177-187, Mutation research
— id: 156607, year: 1990, vol: 233, page: 177, stat: Journal Article,

MUTAGENESIS BY N-NITROSO COMPOUNDS - RELATIONSHIPS TO DNA ADDUCTS, DNA-REPAIR, AND MUTATIONAL EFFICIENCIES
GUTTENPLAN, JB
1990 ;233(1-2):177-187 NOV-DEC, Mutation research. DNA repair reports
— id: 154559, year: 1990, vol: 233, page: 177, stat: Journal Article,

An important role for cytosol in the microsomal metabolism of N-nitrosodimethylamine to a mutagen: evidence for two different mutagenic metabolites
Guttenplan, J B
1989 Sep;47(1-2):63-67, Cancer letters
— id: 156608, year: 1989, vol: 47, page: 63, stat: Journal Article,

MUTATIONAL SPECIFICITIES OF N-NITROSO COMPOUNDS AND SMOKELESS TOBACCO EXTRACTS
GUTTENPLAN, JB; ZIELENSKA, M
1988 ;29(3):101-101 MAR, Proceedings (American Association for Cancer Research)
— id: 154565, year: 1988, vol: 29, page: 101, stat: Journal Article,

Different mutational profiles induced by N-nitroso-N-ethylurea: effects of dose and error-prone DNA repair and correlations with DNA adducts
Zielenska, M; Beranek, D; Guttenplan, J B
1988 ;11(4):473-485, Environmental & molecular mutagenesis
— id: 156611, year: 1988, vol: 11, page: 473, stat: Journal Article,

DNA binding by [2,5-14C]N-nitrosopyrrolidine in excision-repair proficient and deficient strains of Salmonella. Evidence for a major premutagenic adduct
Zielenska, M; Guttenplan, J B
1988 Oct;9(10):1901-1904, Carcinogenesis
— id: 156610, year: 1988, vol: 9, page: 1901, stat: Journal Article,

Mutagenic activity and specificity of N-nitrosomethylaniline and N-nitrosodiphenylamine in Salmonella
Zielenska, M; Guttenplan, J B
1988 Nov;202(1):269-276, Mutation research
— id: 156609, year: 1988, vol: 202, page: 269, stat: Journal Article,

MODIFICATION OF DEOXYGUANOSINE (DG) AND DEOXYGUANOSINE MONOPHOSPHATE (DGMP) BY BIS(CHLOROMETHYL) ETHER (BCME)
Baten, A; Vanduuren, BL; Guttenplan, JB
1987 Mar;28(3):92-92, Proceedings (American Association for Cancer Research)
— id: 31215, year: 1987, vol: 28, page: 92, stat: Journal Article,

Structure-activity relationships in metabolism and mutagenicities of N-nitrosamines
Guttenplan JB
1987 ;(84):129-131, IARC scientific publications (Lyon)
— id: 11402, year: 1987, vol: , page: 129, stat: Journal Article,

Mutagenic activity in smokeless tobacco products sold in the USA
Guttenplan, J B
1987 May;8(5):741-743, Carcinogenesis
— id: 156614, year: 1987, vol: 8, page: 741, stat: Journal Article,

N-nitrosamines: bacterial mutagenesis and in vitro metabolism
Guttenplan, J B
1987 Sep;186(2):81-134, Mutation research
— id: 156612, year: 1987, vol: 186, page: 81, stat: Journal Article,

N-NITROSAMINES - BACTERIAL MUTAGENESIS AND INVITRO METABOLISM
GUTTENPLAN, JB
1987 ;186(2):81-134 SEP, Mutation research. DNA repair reports
— id: 154569, year: 1987, vol: 186, page: 81, stat: Journal Article,

CISPLATIN NEPHROTOXICITY - INSIGHTS INTO MECHANISM
SAFIRSTEIN, R; WINSTON, J; MOEL, D; DIKMAN, S; GUTTENPLAN, J
1987 ;10(1):325-346 FEB, International journal of andrology
— id: 154573, year: 1987, vol: 10, page: 325, stat: Journal Article,

Effects of UV repair, error-prone repair and critical site of mutation on mutagenesis induced by N-nitrosamines
Zielenska, M; Guttenplan, J B
1987 Sep;180(1):11-20, Mutation research
— id: 156613, year: 1987, vol: 180, page: 11, stat: Journal Article,

DNA-BINDING BY (2,5-C-14)-N-NITROSOPYRROLIDINE IN EXCISION-REPAIR PROFICIENT AND DEFICIENT STRAINS OF SALMONELLA
ZIELENSKA, M; GUTTENPLAN, JB
1987 MAR;28:94-94, Proceedings (American Association for Cancer Research)
— id: 156990, year: 1987, vol: 28, page: 94, stat: Journal Article,

MUTAGENIC ACTIVITY OF N-NITROSOMETHYLANILINE AND N-NITROSODIPHENYLAMINE IN SALMONELLA-TYPHIMURIUM TA104 AND RELATED STRAINS
ZIELENSKA, M; GUTTENPLAN, JB
1987 ;9:118-118, Environmental mutagenesis
— id: 156991, year: 1987, vol: 9, page: 118, stat: Journal Article,

STRUCTURE-ACTIVITY-RELATIONSHIPS IN ALPHA-OXIDATION AND MUTAGENICITIES OF N-NITROSAMINES
GUTTENPLAN, JB
1986 MAR;27:96-96, Proceedings (American Association for Cancer Research)
— id: 156989, year: 1986, vol: 27, page: 96, stat: Journal Article,

CISPLATIN NEPHROTOXICITY
SAFIRSTEIN, R; WINSTON, J; GOLDSTEIN, M; MOEL, D; DIKMAN, S; GUTTENPLAN, J
1986 ;8(5):356-367 NOV, American journal of kidney diseases
— id: 154580, year: 1986, vol: 8, page: 356, stat: Journal Article,

EFFECTS OF UV REPAIR, ERROR PRONE REPAIR AND SITES OF BASE PAIR DAMAGE ON MUTAGENESIS BY NITROSAMINES
ZIELINSKA, M; GUTTENPLAN, JB
1986 ;8(3):95-96 MAR, Environmental mutagenesis
— id: 154589, year: 1986, vol: 8, page: 95, stat: Journal Article,

INCORPORATION OF 7-METHYLGUANINE INTO KNOWN A POSITION IN PBR322 - A POTENTIAL METHOD FOR THE SITE-SPECIFIC INTRODUCTION OF APURINIC SITES
FLIESSBACH, JH; KEITH, JM; GUTTENPLAN, JB
1985 ;26(MAR):88-88, Proceedings (American Association for Cancer Research)
— id: 156988, year: 1985, vol: 26, page: 88, stat: Journal Article,

Evidence for a major premutagenic ethyldeoxythymidine-DNA adduct in an in vivo system: N-nitroso-N-ethylurea-treated Salmonella typhimurium
Hu, Y C; Guttenplan, J B
1985 Oct;6(10):1513-1516, Carcinogenesis
— id: 156615, year: 1985, vol: 6, page: 1513, stat: Journal Article,

MUTAGENESIS BY N-NITROSO-N-ETHYLUREA (NEU) AND ETHYLMETHANESULFONATE (EMS) IN SALMONELLA TESTER STRAINS WITH A-T BASE-PAIRS AT THE SITE OF MUTATION - EVIDENCE FOR A MAJOR PREMUTAGENIC ETHYLTHYMIDINE (ETT) DNA ADDUCT
HU, YC; GUTTENPLAN, JB
1985 ;7(169-):46-46, Environmental mutagenesis
— id: 154590, year: 1985, vol: 7, page: 46, stat: Journal Article,

Mutagenesis and O6-ethylguanine levels in DNA from N-nitroso-N-ethylurea-treated Salmonella typhimurium: evidence for a high mutational efficiency of O6-ethylguanine
Guttenplan, J B
1984 Feb;5(2):155-159, Carcinogenesis
— id: 156618, year: 1984, vol: 5, page: 155, stat: Journal Article,

Mutagenesis by N-nitroso compounds in Salmonella typhimurium TA102 and TA104: evidence for premutagenic adenine or thymine DNA adducts
Guttenplan, J B; Hu, Y C
1984 Nov-Dec;141(3-4):153-159, Mutation research
— id: 156616, year: 1984, vol: 141, page: 153, stat: Journal Article,

SPECIES-DIFFERENCES IN THE INVITRO METABOLISM OF N-NITRO-SAMINES TO MOLECULAR NITROGEN
GUTTENPLAN, JB; BANARJEE, S
1984 ;25(MAR):119-119, Proceedings (American Association for Cancer Research)
— id: 40960, year: 1984, vol: 25, page: 119, stat: Journal Article,

MUTAGENESIS BY N-NITROSO COMPOUNDS IN SALMONELLA-TYPHIMURIUM TA102 AND TA104 - EVIDENCE FOR PREMUTAGENIC ADENINE OR THYMINE DNA ADDUCTS
GUTTENPLAN, JB; HU, YC
1984 ;141(3-4):153-159, Mutation research. DNA repair reports
— id: 154594, year: 1984, vol: 141, page: 153, stat: Journal Article,

DIABETES (D) PROTECTS RATS FROM CISPLATIN-INDUCED (CP) ACUTE-RENAL-FAILURE (ARF)
SAFIRSTEIN, R; GUTTENPLAN, J
1984 ;25(MAR):370-370, Proceedings (American Association for Cancer Research)
— id: 154596, year: 1984, vol: 25, page: 370, stat: Journal Article,

Uptake and metabolism of cisplatin by rat kidney
Safirstein, R; Miller, P; Guttenplan, J B
1984 May;25(5):753-758, Kidney international
— id: 156617, year: 1984, vol: 25, page: 753, stat: Journal Article,

A SIMPLIFIED INVITRO ASSAY FOR THE DETERMINATION OF MOLECULAR NITROGEN GENERATED BY THE ALPHA-OXIDATIVE METABOLISM OF N-NITROSAMINES
GUTTENPLAN, JB
1983 ;24(MAR):82-82, Proceedings (American Association for Cancer Research)
— id: 154600, year: 1983, vol: 24, page: 82, stat: Journal Article,

Mutagenic activity and identification of excreted platinum in human and rat urine and rat plasma after administration of cisplatin
Safirstein, R; Daye, M; Guttenplan, J B
1983 Apr;18(3):329-338, Cancer letters
— id: 156620, year: 1983, vol: 18, page: 329, stat: Journal Article,

Inhibition of amino acid transport by cis-diamminedichloroplatinum(II) derivatives in L1210 murine leukemia cells
Scanlon, K J; Safirstein, R L; Thies, H; Gross, R B; Waxman, S; Guttenplan, J B
1983 Sep;43(9):4211-4215, Cancer research
— id: 156619, year: 1983, vol: 43, page: 4211, stat: Journal Article,

On the effects of pH on mutagenesis induced by N-nitroso compounds
Guttenplan, J B; Milstein, S
1982 Mar;93(1):249-250, Mutation research
— id: 156621, year: 1982, vol: 93, page: 249, stat: Journal Article,

Resistance of Salmonella typhimurium TA 1535 to O6-guanine methylation and mutagenesis induced by low doses of N-methyl-N'-nitro-N-nitrosoguanidine: an apparent constitutive repair activity
Guttenplan, J B; Milstein, S
1982 ;3(3):327-331, Carcinogenesis
— id: 156622, year: 1982, vol: 3, page: 327, stat: Journal Article,

ALKYLATION OF DNA IN SALMONELLA-TYPHIMURIUM BY N-ETHYL-N-NITROSOUREA AND THE RELATIONSHIP OF ADDUCTS TO MUTAGENESIS
GUTTENPLAN, JB
1982 ;23(MAR):94-94, Proceedings (American Association for Cancer Research)
— id: 154606, year: 1982, vol: 23, page: 94, stat: Journal Article,

CONSTITUATIVE O-6-ALKYL REPAIR ACTIVITY IN SALMONELLA-TYPHIMURIUM TESTER STRAINS
LEE, SY; GUTTENPLAN, JB
1982 ;4(3):385-385, Environmental mutagenesis
— id: 154605, year: 1982, vol: 4, page: 385, stat: Journal Article,

INHIBITION OF THE ASC AMINO-ACID TRANSPORT-SYSTEM BY CISPLATIN (CISPT) DERIVATIVES IN L1210 CELLS
SCANLON, KJ; SAFIRSTEIN, R; GUTTENPLAN, JB; THIES, HL; WAXMAN, S
1982 ;23(MAR):167-167, Proceedings (American Association for Cancer Research)
— id: 154607, year: 1982, vol: 23, page: 167, stat: Journal Article,

Salivary levels of N-nitrosamines and some metabolites after IP injection of N-nitrosamines in rats
Fliessbach, J H; Guttenplan, J B
1981 Aug;33(2):283-291, Research communications in chemical pathology & pharmacology
— id: 156623, year: 1981, vol: 33, page: 283, stat: Journal Article,

Activation of promutagens by liver homogenates isolated from female mice at different ages; lack of significant differences
Guttenplan, J B; Bliznakov, E G
1981 May;16(1):29-35, Mechanisms of aging & development
— id: 156624, year: 1981, vol: 16, page: 29, stat: Journal Article,

A correlation between mutagenic and carcinogenic potencies in a diverse group of N-nitrosamines: determination of mutagenic activities of weakly mutagenic N-nitrosamines
Lee, S Y; Guttenplan, J B
1981 ;2(12):1339-1344, Carcinogenesis
— id: 156625, year: 1981, vol: 2, page: 1339, stat: Journal Article,

MUTAGENIC ACTIVITIES OF WEAKLY MUTAGENIC N-NITROSAMINES
LEE, SY; GUTTENPLAN, JB
1981 ;3(3):332-332, Environmental mutagenesis
— id: 154612, year: 1981, vol: 3, page: 332, stat: Journal Article,

Enhanced mutagenic activities of N-nitroso compounds in weakly acidic media
Guttenplan, J B
1980 May;1(5):439-444, Carcinogenesis
— id: 156626, year: 1980, vol: 1, page: 439, stat: Journal Article,

COMPARATIVE MUTAGENICITIES OF METHYLETHYLNITROSAMINE, DIMETHYLNITROSAMINE AND DIETHYLNITROSAMINE
GUTTENPLAN, JB
1980 ;2(2):273-273, Environmental mutagenesis
— id: 154616, year: 1980, vol: 2, page: 273, stat: Journal Article,

RECOVERY OF BENZO(A)PYRENE (BP) METABOLITES AND DIMETHYLNITROSAMINE (DMN) IN RAT SALIVA
GUTTENPLAN, JB; BONOMO, R; FLIESSBACH, JH
1980 ;21(MAR):124-124, Proceedings (American Association for Cancer Research)
— id: 154621, year: 1980, vol: 21, page: 124, stat: Journal Article,

Kinetics of benzo[a]pyrene induced mutagenesis in a highly sensitive salmonella/microsome assay
Unger, J; Guttenplan, J B
1980 Mar;77(3):221-228, Mutation research
— id: 156627, year: 1980, vol: 77, page: 221, stat: Journal Article,

KINETICS OF BENZO[ALPHA]PYRENE INDUCED MUTAGENESIS IN A HIGHLY SENSITIVE SALMONELLA-MICROSOME ASSAY
UNGER, J; GUTTENPLAN, JB
1980 ;77(3):221-228, Mutation research. DNA repair reports
— id: 154625, year: 1980, vol: 77, page: 221, stat: Journal Article,

Comutagenic effects exerted by N-nitroso compounds
Guttenplan, J B
1979 Jan;66(1):25-32, Mutation research
— id: 156630, year: 1979, vol: 66, page: 25, stat: Journal Article,

Detection of trace amounts of dimethylnitrosamine in a modified Salmonella/microsome assay
Guttenplan, J B
1979 Apr;64(2):91-94, Mutation research
— id: 156628, year: 1979, vol: 64, page: 91, stat: Journal Article,

DETECTION OF TRAC AMOUNTS OF DIMETHYLNITROSAMINE IN A MODIFIED SALMONELLA-MICROSOME ASSAY
GUTTENPLAN, JB
1979 ;64(2):91-94, Mutation research. DNA repair reports
— id: 154629, year: 1979, vol: 64, page: 91, stat: Journal Article,

Near quantitative production of molecular nitrogen from metabolism of dimethylnitrosamine
Milstein, S; Guttenplan, J B
1979 Mar;87(1):337-342, Biochemical & biophysical research communications
— id: 156629, year: 1979, vol: 87, page: 337, stat: Journal Article,

KINETICS, DECOMPOSITION PRODUCTS AND FACTORS AFFECTING THE MUTAGENIC ACTIVITY OF N-METHYL-N-NITROSOUREA
MILSTEIN, S; GUTTENPLAN, JB
1979 ;1(2):135-136, Environmental mutagenesis
— id: 154626, year: 1979, vol: 1, page: 135, stat: Journal Article,

RECOVERY OF BENZO(A)PYRENE, 3-METHYLCHOLANTHRENE AND THEIR METABOLITES IN RAT SALIVA AFTER IP INJECTION
SNYDER, W; GUTTENPLAN, JB
1979 ;38(3):660-660, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 154635, year: 1979, vol: 38, page: 660, stat: Journal Article,

EFFECTS OF BILE-ACIDS ON MICROSOMAL METABOLISM OF, AND MUTAGENESIS BY BENZO(A)PYRENE
UNGER, J; GUTTENPLAN, JB
1979 ;20(MAR):132-132, Proceedings (American Association for Cancer Research)
— id: 154628, year: 1979, vol: 20, page: 132, stat: Journal Article,

Mechanisms of inhibition by ascorbate of microbial mutagenesis induced by N-nitroso compounds
Guttenplan, J B
1978 Jul;38(7):2018-2022, Cancer research
— id: 156631, year: 1978, vol: 38, page: 2018, stat: Journal Article,

DETECTION OF CARCINOGENS AND MUTAGENS IN ORAL FLUID
SNYDER, W; MITCHELL, OG; GUTTENPLAN, JB
1978 ;190(2):622-623, Anatomical record
— id: 91282, year: 1978, vol: 190, page: 622, stat: Journal Article,

Inhibition by L-ascorbate of bacterial mutagenesis induced by two N-nitroso compounds
Guttenplan, J B
1977 Jul;268(5618):368-370, Nature
— id: 156632, year: 1977, vol: 268, page: 368, stat: Journal Article,

Factors affecting the induction of dimethylnitrosamine demethylase by Aroclor 1254
Guttenplan, J B; Garro, A J
1977 Jan;37(1):329-330, Cancer research
— id: 156633, year: 1977, vol: 37, page: 329, stat: Journal Article,

Vinyl chloride dependent mutagensis: effects of liver extracts and free radicals
Garro, A J; Guttenplan, J B; Milvy, P
1976 Apr;38(2):81-88, Mutation research
— id: 156635, year: 1976, vol: 38, page: 81, stat: Journal Article,

Effects of cytochrome p-448 and p-450 inducers on microsomal dimethylnitrosamine demethylase activity and the capacity of isolated microsomes to activate dimethylnitrosamine to a mutagen
Guttenplan, J B; Hutterer, F; Garro, A J
1976 Jun;35(3):415-422, Mutation research
— id: 156634, year: 1976, vol: 35, page: 415, stat: Journal Article,

Tertiary and quaternary structure of tobacco mosaic virus and protein. I. Effect of pH on fluorescence and 2-p-toluidinylnaphthalene-6-sulfonate binding
Guttenplan, J B; Calvin, M
1973 Oct;322(2):294-300, Biochimica & biophysica acta
— id: 156637, year: 1973, vol: 322, page: 294, stat: Journal Article,

Tertiary and quaternary structure of tobacco mosaic virus and protein. II. Emission, excitation, polarization and position of 2-p-toluidinylnaphthalene-6-sulfonate binding
Guttenplan, J B; Calvin, M
1973 Oct;322(2):301-320, Biochimica & biophysica acta
— id: 156636, year: 1973, vol: 322, page: 301, stat: Journal Article,