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Sumayah Jamal

Clinical Assistant Professor, Department of Ronald O. Perelman Department of Dermatology;Research Assistant Professor, Department of Microbiology

Contact Info



1994 — NYU, Medical Education
1994-1995 — Columbia Presbyterian, Dept. of Medicine 7/1/1994-6/30/1995, Internship
1995-1998 — NYU, Dept. of Dermatology 7/1/1995-6/30/1998, Residency Training

Research Summary

While the cure rate for localized melanoma approaches 100% using surgical modalities, the prognosis for metastatic melanoma is poor indeed. It is therefore necessary to find effective and specific therapeutic modalities for this devastating disease entity. My lab investigates molecular mechanisms that promote melanoma invasion.
Specifically we are studying the role of the endothelin pathway in melanoma development and progression. Importantly we are looking at drugs that specifically block this pathway in vivo. Our current studies focus on the regulation of adhesion molecule expression by endothelin in melanocytes and melanoma cells. We are also conducting animal studies investigating the ability of endothelin receptor antagonists to prevent melanoma metastasis. We anticipate conducting phase I clinical trials using these antagonists in the foreseeable future.

Research Interests

Malignant Melanoma

Akt and PI3K-dependent but CREB-independent upregulation of MCAM by endothelin-3 in human melanocytes
Williams, Brittny; Schneider, Robert J; Jamal, Sumayah
2014-05-08; 0960-8931,Melanoma research - id: 962552, year: 2014 JOURNAL ARTICLE

Skin cancer awareness in communities of color
Imahiyerobo-Ip, Joyce; Ip, Ivan; Jamal, Sumayah; Nadiminti, Uma; Sanchez, Miguel
2012-02-05; 1097-6787,Journal of the American Academy of Dermatology - id: 133200, year: 2011

Regulation of Melanoma Cell Adhesion Molecule by endothelin-1 in human melanocytes
Jamal, S; Williams, BS
2012-02-05; 0022-202X,Journal of investigative dermatology - id: 70335, year: 2006

Endothelin-1 induces CXCL1 and CXCL8 secretion in human melanoma cells
Mangahas, Catherine R; dela Cruz, Gelo V; Friedman-Jimenez, George; Jamal, Sumayah
2012-02-05; 0022-202X,Journal of investigative dermatology - id: 57870, year: 2005 Journal Article

Endothelin-1 upregulates MCAM in melanocytes
Mangahas, Catherine R; dela Cruz, Gelo V; Schneider, Robert J; Jamal, Sumayah
2012-02-05; 0022-202X,Journal of investigative dermatology - id: 47756, year: 2004 Journal Article