Fredrick F Jaffe, M.D.

Heterotopic ossification after total hip arthroplasty
Cohn, Randy M; Schwarzkopf, Ran; Jaffe, Fredrick
2011 Nov;40(11):E232-E235, American journal of orthopedics (Belle Mead, NJ)
Heterotopic ossification (HO), the development of bone outside its normal location in the skeleton, can compromise outcomes of total hip arthroplasty (THA). The etiopathogenesis of HO, though incompletely understood, involves genetic abnormalities, neurologic injury, and musculoskeletal trauma. Several systems are used to classify severity of HO after THA. Numerous risk factors for HO, including patient factors and surgical techniques, have been described. Prophylaxis against HO traditionally has involved radiation therapy or use of nonsteroidal anti-inflammatory drugs. Once formed, heterotopic bone can be managed only with surgical excision
— id: 150568, year: 2011, vol: 40, page: E232, stat: Journal Article,

The predictive power of preoperative hip range of motion for the development of heterotopic ossification
Schwarzkopf, Ran; Cohn, Randy M; Skoda, Emily C; Walsh, Michael; Jaffe, Fredrick
2011 Mar;34(3):169-169, Orthopedics (Thorofare NJ)
Postoperative development of heterotopic ossification can compromise the success of total hip arthroplasty (THA). Heterotopic ossification has been associated with decreased postoperative hip range of motion (ROM), potentially leading to poor patient satisfaction with outcome. Many risk factors predisposing to heterotopic ossification have been discussed in the literature, including sex, age, operative time, surgical approach, and preoperative function. The goal of this study was to examine if preoperative ROM is a risk factor for the development of severe heterotopic ossification after THA, and the impact of severe heterotopic ossification formation on the gain in ROM following THA. In a retrospective study of a single surgeon's 20-year experience, all patients who developed type III heterotopic ossification after THA were evaluated for hip ROM preoperatively and at 1-year follow-up. Total ROM was classified according to the modified Merle d'Aubigne score, and Harris Hip Scores were calculated. A statistically significant difference was found in preoperative external rotation in the study group compared to the control group (P<.001). At 1 year postoperatively, hip ROM differences were significant in external rotation (P<.001), internal rotation (P<.001), and abduction (P<.05). The modified Merle d'Aubigne score was significantly different between the groups (P<.001). Although many factors have been shown to influence the development of heterotopic ossification following THA, we found that a decrease in preoperative external rotation may point to an increased risk. Surgeons should consider this data when considering the use of prophylactic treatment to avoid the development of heterotopic ossification
— id: 131812, year: 2011, vol: 34, page: 169, stat: Journal Article,

Posterior cruciate ligament-sparing versus posterior cruciate ligament-sacrificing arthroplasty. Functional results using the same prosthesis
Pereira DS; Jaffe FF; Ortiguera C
1998 Feb;13(2):138-144, Journal of arthroplasty
The functional outcomes of 143 total knee arthroplasties performed by 1 surgeon between 1988 and 1992 were reviewed. Ninety-three procedures were carried out with sacrifice of the posterior cruciate ligament (PCL); in 50, the PCL was preserved. All cases were performed using the Kinemax prosthesis (Howmedica, Rutherford, NJ). Demographically, there were no differences between the 2 patient groups. Patients were evaluated over a mean follow-up period of 3 years (range, 2-6 years) using the 100-point Hospital for Special Surgery knee scoring system. The data revealed no difference in clinical or early radiographic outcome between PCL-sacrificing and PCL-retaining arthroplasties and support the argument that PCL sacrifice should be considered in cases in which extensive releases and complex ligamentous balancing are required
— id: 30803, year: 1998, vol: 13, page: 138, stat: Journal Article,

Osteoarthritis associated with osteopetrosis treated by total knee arthroplasty. Report of a case
Casden, A M; Jaffe, F F; Kastenbaum, D M; Bonar, S F
1989 Oct;(247):202-207, Clinical orthopaedics & related research
Osteopetrosis is due to a defect in osteoclastic cell function and results in osteosclerosis and progressive obliteration of the marrow spaces. Early onset osteoarthritis is associated with osteopetrosis. The authors describe a case of early onset osteoarthritis associated with osteopetrosis treated by total knee arthroplasty. The marblelike quality of osteopetrotic bone makes surgical treatment of these patients technically challenging and requires modification of standard surgical technique
— id: 131512, year: 1989, vol: , page: 202, stat: Journal Article,

A severe reaction to dextran despite hapten inhibition
Bernstein RL; Rosenberg AD; Pada EY; Jaffe FF
1987 Oct;67(4):567-569, Anesthesiology
— id: 45566, year: 1987, vol: 67, page: 567, stat: Journal Article,