Sherif Ibrahim, M.D., Ph.D

Notch pathway activation targets AML-initiating cell homeostasis and differentiation
Lobry, Camille; Ntziachristos, Panagiotis; Ndiaye-Lobry, Delphine; Oh, Philmo; Cimmino, Luisa; Zhu, Nan; Araldi, Elisa; Hu, Wenhuo; Freund, Jacquelyn; Abdel-Wahab, Omar; Ibrahim, Sherif; Skokos, Dimitris; Armstrong, Scott A; Levine, Ross L; Park, Christopher Y; Aifantis, Iannis
2013 Feb;210(2):301-319, Journal of experimental medicine
— id: 220852, year: 2013, vol: 210, page: 301, stat: Journal Article,

Regulation of c-Myc Ubiquitination Controls Chronic Myelogenous Leukemia Initiation and Progression
Reavie, Linsey; Buckley, Shannon M; Loizou, Evangelia; Takeishi, Shoichiro; Aranda-Orgilles, Beatriz; Ndiaye-Lobry, Delphine; Abdel-Wahab, Omar; Ibrahim, Sherif; Nakayama, Keiichi I; Aifantis, Iannis
2013 Mar;23(3):362-375, Cancer cell
— id: 255272, year: 2013, vol: 23, page: 362, stat: Journal Article,

Identification of ex vivo myeloma cells with the pnh phenotype
Araten, D J; Csehak, K; Zamechek, L; Park, J; Liu, C; Ibrahim, S; Mazumder, A
2012 16 Nov 2012;:-, Blood
— id: 217012, year: 2012, vol: , page: , stat: Journal Article,

A Role for TET2 Mutations in Paroxysmal Nocturnal Hemoglobinuria (PNH)
Araten, David J.; Bains, Ashish; Lobry, Camille; Aifantis, Iannis; Ibrahim, Sherif
2012 NOV 16;120(21):-, Blood
— id: 227382, year: 2012, vol: 120, page: , stat: Journal Article,

Leukemic blasts with the paroxysmal nocturnal hemoglobinuria phenotype in children with acute lymphoblastic leukemia
Araten, David J; Sanders, Katie J; Anscher, Dan; Zamechek, Leah; Hunger, Stephen P; Ibrahim, Sherif
2012 Nov;181(5):1862-1869, American journal of pathology
— id: 180502, year: 2012, vol: 181, page: 1862, stat: Journal Article,

CD163 versus CD68 in tumor associated macrophages of classical hodgkin lymphoma
Harris, Jonathan A; Jain, Salvia; Ren, Qinghu; Zarineh, Alirezah; Liu, Cynthia; Ibrahim, Sherif
2012 ;7:12-12, Diagnostic pathology
— id: 157482, year: 2012, vol: 7, page: 12, stat: Journal Article,

Primary Effusion Lymphoma with Central Nervous System Involvement in an HIV-Negative Homosexual Male
Kabiawu-Ajise, Oluyomi E; Harris, Jonathan; Ismaili, Naima; Amorosi, Edward; Ibrahim, Sherif
2012 ;128(2):77-82, Acta haematologica
— id: 175771, year: 2012, vol: 128, page: 77, stat: Journal Article,

A JAK2-V617F mutation patient developed Philadelphia positive CML/AP - a case report
Liu, C.; Amorosi, E.; Ibrahim, S.
2012 OCT;61 1 1(SI):120-120, Histopathology
— id: 178292, year: 2012, vol: 61 1 1, page: 120, stat: Journal Article,

Sindbis viral vectors target hematopoietic malignant cells
Suzme, R; Tseng, J-C; Levin, B; Ibrahim, S; Meruelo, D; Pellicer, A
2012 Nov;19(11):757-766, Cancer gene therapy
— id: 180084, year: 2012, vol: 19, page: 757, stat: Journal Article,

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia
Klinakis, Apostolos; Lobry, Camille; Abdel-Wahab, Omar; Oh, Philmo; Haeno, Hiroshi; Buonamici, Silvia; van De Walle, Inge; Cathelin, Severine; Trimarchi, Thomas; Araldi, Elisa; Liu, Cynthia; Ibrahim, Sherif; Beran, Miroslav; Zavadil, Jiri; Efstratiadis, Argiris; Taghon, Tom; Michor, Franziska; Levine, Ross L; Aifantis, Iannis
2011 May 12;473(7346):230-233, Nature
— id: 134267, year: 2011, vol: 473, page: 230, stat: Journal Article,

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
Moran-Crusio, Kelly; Reavie, Linsey; Shih, Alan; Abdel-Wahab, Omar; Ndiaye-Lobry, Delphine; Lobry, Camille; Figueroa, Maria E; Vasanthakumar, Aparna; Patel, Jay; Zhao, Xinyang; Perna, Fabiana; Pandey, Suveg; Madzo, Jozef; Song, Chunxiao; Dai, Qing; He, Chuan; Ibrahim, Sherif; Beran, Miloslav; Zavadil, Jiri; Nimer, Stephen D; Melnick, Ari; Godley, Lucy A; Aifantis, Iannis; Levine, Ross L
2011 Jul 12;20(1):11-24, Cancer cell
— id: 135262, year: 2011, vol: 20, page: 11, stat: Journal Article,

The human Rgr oncogene is overexpressed in T-cell malignancies and induces transformation by acting as a GEF for Ras and Ral
Osei-Sarfo, K; Martello, L; Ibrahim, S; Pellicer, A
2011 Aug 25;30(34):3661-3671, Oncogene
— id: 136936, year: 2011, vol: 30, page: 3661, stat: Journal Article,

Circulating cytokines and risk of B-cell non-Hodgkin lymphoma: a prospective study
Gu, Yian; Shore, Roy E; Arslan, Alan A; Koenig, Karen L; Liu, Mengling; Ibrahim, Sherif; Lokshin, Anna E; Zeleniuch-Jacquotte, Anne
2010 Aug;21(8):1323-1333, Cancer causes & control. ccc
— id: 138134, year: 2010, vol: 21, page: 1323, stat: Journal Article,

A High Frequency of Blasts with the PNH Phenotype in Patients with ALL
Araten, D; Sanders, KJ; Anscher, D; Zamechek, L; Hunger, SP; Ibrahim, S
2009 NOV 20 ;114(22):630-630, Blood
— id: 109979, year: 2009, vol: 114, page: 630, stat: Journal Article,

Is JAK2 inducible by cytotoxic chemotherapy?
Bendaly E.A.; Rahman S.S.; Zafar S.; Haglof K.; Ibrahim S.; Raphael B.G.
2009 ;114(22):?-? #4979, Blood
— id: 112215, year: 2009, vol: 114, page: ?, stat: Journal Article,

CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia
Buonamici, Silvia; Trimarchi, Thomas; Ruocco, Maria Grazia; Reavie, Linsey; Cathelin, Severine; Mar, Brenton G; Klinakis, Apostolos; Lukyanov, Yevgeniy; Tseng, Jen-Chieh; Sen, Filiz; Gehrie, Eric; Li, Mengling; Newcomb, Elizabeth; Zavadil, Jiri; Meruelo, Daniel; Lipp, Martin; Ibrahim, Sherif; Efstratiadis, Argiris; Zagzag, David; Bromberg, Jonathan S; Dustin, Michael L; Aifantis, Iannis
2009 Jun 18;459(7249):1000-1004, Nature
— id: 105354, year: 2009, vol: 459, page: 1000, stat: Journal Article,

Postchemotherapy histiocyte-rich pseudotumor involving the spleen
Chandra, Pranil; Wen, Yong Hannah; Tuli, Sandeep; Raphael, Bruce G; Amorosi, Edward L; Medeiros, L Jeffrey; Ibrahim, Sherif
2009 Sep;132(3):342-348, American journal of clinical pathology
— id: 114480, year: 2009, vol: 132, page: 342, stat: Journal Article,

Thrombin induces tumor cell cycle activation and spontaneous growth by down-regulation of p27Kip1, in association with the up-regulation of Skp2 and MiR-222
Hu, Liang; Ibrahim, Sherif; Liu, Cynthia; Skaar, Jeffrey; Pagano, Michele; Karpatkin, Simon
2009 Apr 15;69(8):3374-3381, Cancer research
— id: 98895, year: 2009, vol: 69, page: 3374, stat: Journal Article,

Clinical application of dendritic cells and interleukin-2 and tools to study activated T cells in horses-First results and implications for quality control
Steinbach, Falko; Bischoff, Sabine; Freund, Hannah; Metzner-Flemisch, Simone; Ibrahim, Sherif; Walter, Jakob; Wilke, Ingo; Mauel, Susanne
2009 Mar 15;128(1-3):16-23, Veterinary immunology & immunopathology
— id: 95587, year: 2009, vol: 128, page: 16, stat: Journal Article,

Regression of HIV-related diffuse large B-cell lymphoma in response to antiviral therapy alone
Amengual, Jennifer E; Zhang, Xinmin; Ibrahim, Sherif; Gardner, Lawrence B
2008 Nov 15;112(10):4359-4360, Blood
— id: 95588, year: 2008, vol: 112, page: 4359, stat: Journal Article,

Measurements of Heterogeneity of Bone Marrow Cellularity
Goldenberg A; Haglof K; Kelley P; Davis G; Liu C; Ibrahim S
2008 ;112:- #4700, Blood
— id: 92855, year: 2008, vol: 112, page: , stat: Journal Article,

Thrombin Enhances Spontaneous Tumor Growth and Cell Cycle Activation by Downregulation of p27(Kipl) and Upregulation of Skp2 and MiR-222
Hu, L; Ibrahim, S; Liu, C; Skaar, J; Pagano, M; Karpatkin, S
2008 NOV 16 ;112(11):152-152, Blood
— id: 93282, year: 2008, vol: 112, page: 152, stat: Journal Article,

Twist is required for thrombin-induced tumor angiogenesis and growth
Hu, Liang; Roth, Jennifer M; Brooks, Peter; Ibrahim, Sherif; Karpatkin, Simon
2008 Jun 1;68(11):4296-4302, Cancer research
— id: 81059, year: 2008, vol: 68, page: 4296, stat: Journal Article,

Expression of junctional adhesion molecule-C (JAM-C) in B-cell lymphoprol iterative disorder - A preliminary flow cytometric analysis of 30 cases
Li, X; Zhang, XM; Ibrahim, S; Liu, C
2008 JAN ;21(2):262A-262A, Modern pathology
— id: 75920, year: 2008, vol: 21, page: 262A, stat: Journal Article,

Expression of junctional adhesion molecule-C (JAM-C) in B-cell lymphoproliferative disorder - A preliminary flow cytometric analysis of 30 cases
Li, X; Zhang, XM; Ibrahim, S; Liu, C
2008 JAN ;88(2):262A-262A, Laboratory investigation
— id: 75941, year: 2008, vol: 88, page: 262A, stat: Journal Article,

Betaig-h3 tumor suppressor gene expression is absent in human low-grade follicular lymphoma but not in high-grade follicular lymphoma
Shah, JN; Liu, C; Zhao, Y; Formenti, SC; Ibrahim, S
2008 AUG ;72(1):S472-S472, International journal of radiation oncology biology physics
— id: 86797, year: 2008, vol: 72, page: S472, stat: Journal Article,

Expression of intracellular domain of notch1 (ICN1), Lef-1, and phosphorylated STAT3 (pSTAT3) in angioimmunoblastic T-cell lymphoma
Zhang, XM; Li, X; Chiriboga, L; Chandra, P; Lee, P; Ibrahim, S
2008 JAN ;21(2):284A-284A, Modern pathology
— id: 75921, year: 2008, vol: 21, page: 284A, stat: Journal Article,

Expression of intracellular domain of notchl (ICN1), lef-1, and phosphorylated STAT3 (Pstat3) in angioimmunoblastic T-cell lymphoma
Zhang, XM; Li, X; Chiriboga, L; Chandra, P; Lee, P; Ibrahim, S
2008 JAN ;88(2):284A-284A, Laboratory investigation
— id: 75942, year: 2008, vol: 88, page: 284A, stat: Journal Article,

Simultaneous plasmablastic myeloma and high-grade follicular lymphoma: Clonal relatedness and therapeutic implications
Chandra, P; Liu, C; Raphael, B; Ishmaili, N; Ibrahim, S
2007 NOV ;9(5):662-663, Journal of molecular diagnostics
— id: 87180, year: 2007, vol: 9, page: 662, stat: Journal Article,

Further analysis of anti-human leukocyte mAbs with reactivity to equine leukocytes by two-colour flow cytometry and immunohistochemistry
Flaminio, M Julia B F; Ibrahim, Sherif; Lunn, D Paul; Stark, Robert; Steinbach, Falko
2007 Sep 15;119(1-2):92-99, Veterinary immunology & immunopathology
— id: 95591, year: 2007, vol: 119, page: 92, stat: Journal Article,

Screening of anti-human leukocyte monoclonal antibodies for reactivity with equine leukocytes
Ibrahim, Sherif; Saunders, Kelly; Kydd, Julia H; Lunn, D Paul; Steinbach, Falko
2007 Sep 15;119(1-2):63-80, Veterinary immunology & immunopathology
— id: 95590, year: 2007, vol: 119, page: 63, stat: Journal Article,

Non-HLDA8 animal homologue section anti-leukocyte mAbs tested for reactivity with equine leukocytes
Ibrahim, Sherif; Steinbach, Falko
2007 Sep 15;119(1-2):81-91, Veterinary immunology & immunopathology
— id: 95592, year: 2007, vol: 119, page: 81, stat: Journal Article,

Further characterization of cross-reactive anti-human leukocyte mAbs by use of equine leukocyte cell lines EqT8888 and eCAS
Steinbach, Falko; Saunders, Kelly; Kydd, Julia H; Ibrahim, Sherif
2007 Sep 15;119(1-2):100-105, Veterinary immunology & immunopathology
— id: 95593, year: 2007, vol: 119, page: 100, stat: Journal Article,

Growth-regulated oncogene is pivotal in thrombin-induced angiogenesis
Caunt, Maresa; Hu, Liang; Tang, Thomas; Brooks, Peter C; Ibrahim, Sherif; Karpatkin, Simon
2006 Apr 15;66(8):4125-4132, Cancer research
— id: 64463, year: 2006, vol: 66, page: 4125, stat: Journal Article,

Association between human parvovirus b19 (HP B19) and acute lymphoblastic leukemia in children
Eltounsi, I; Helwa, M; Al Rashidi, F; Alenzi, F; Bassyouni, M; Fathi, A; Ibrahim, S
2006 NOV 16 ;108(11):197B-197B, Blood
— id: 71218, year: 2006, vol: 108, page: 197B, stat: Journal Article,

Epistaxis and severe weakness in a patient with multiple myeloma. Therapy-related acute myeloid leukemia, pure erythroid leukemia
Guo, Chuanhai; Inghirami, Giorgio; Ibrahim, Sherif; Sen, Filiz
2006 Jul;130(7):1075-1076, Archives of pathology & laboratory medicine
— id: 66470, year: 2006, vol: 130, page: 1075, stat: Journal Article,

Toxicogenomics in drug discovery and drug development: potential applications and future challenges
Khor, Tin Oo; Ibrahim, Sherif; Kong, Ah-Ng Tony
2006 Aug;23(8):1659-1664, Pharmacheutical research
— id: 95594, year: 2006, vol: 23, page: 1659, stat: Journal Article,

8 and 11gauge bone marrow biopsy needle performance characteristics
Goldenberg, A; Kelley, P; Ibrahim, S; Sen, F; Liu, C
2005 NOV 16 ;106(11):483B-483B, Blood
— id: 60237, year: 2005, vol: 106, page: 483B, stat: Journal Article,

Influence of age and needle gauge on bone marrow biopsy specimen adequacy
Goldenberg, A; Kelley, P; Ibrahim, S; Sen, F; Liu, C
2005 NOV 16 ;106(11):483B-484B, Blood
— id: 60238, year: 2005, vol: 106, page: 483B, stat: Journal Article,

Is an increase in CD4/CD8 T-cell ratio in lymph node fine needle aspiration helpful for diagnosing Hodgkin lymphoma? A study of 85 lymph node FNAs with increased CD4/CD8 ratio
Hernandez, Osvaldo; Oweity, Thaira; Ibrahim, Sherif
2005 Sep 9;2:14-14, Cytojournal
— id: 69650, year: 2005, vol: 2, page: 14, stat: Journal Article,

The clinical significance of small monoclonal B cell population detected by flow cytometry in patients with negative morphological findings on bone marrow biopsy
Liu, Q; Inghirami, G; Ibrahim, S; Sen, F; Liu, C
2005 ;85(Suppl 1):240A-240A, Laboratory investigation
— id: 50470, year: 2005, vol: 85, page: 240A, stat: Journal Article,

The clinical significance of small monoclonal B cell population detected by flow cytometry in patients with negative morphological findings on bone marrow biopsy
Liu, Q; Inghirami, G; Ibrahim, S; Sen, F; Liu, C
2005 ;18(Suppl 1):240A-240A, Modern pathology
— id: 50440, year: 2005, vol: 18, page: 240A, stat: Journal Article,

Molecular cloning and characterization of markers and cytokines for equid myeloid cells
Steinbach, Falko; Stark, Robert; Ibrahim, Sherif; Gawad, Eman Abd-El; Ludwig, Hanns; Walter, Jakob; Commandeur, Ulrich; Mauel, Susanne
2005 Oct 18;108(1-2):227-236, Veterinary immunology & immunopathology
— id: 95595, year: 2005, vol: 108, page: 227, stat: Journal Article,

Bone marrow biopsy needle design influences the bone content of recovered specimens
Goldenberg, A; Kelley, P; Liu, C; Sen, F; Ibrahim, S
2004 NOV 16 ;104(11):408B-408B, Blood
— id: 49324, year: 2004, vol: 104, page: 408B, stat: Journal Article,

Degree of CD25 expression in T-cell lymphoma is dependent on tissue site: implications for targeted therapy
Jones, Dan; Ibrahim, Sherif; Patel, Kaushali; Luthra, Rajyalakshmi; Duvic, Madeleine; Medeiros, L Jeffrey
2004 Aug 15;10(16):5587-5594, Clinical cancer research
— id: 95596, year: 2004, vol: 10, page: 5587, stat: Journal Article,

Transient atypical monocytosis mimic acute myelomonocytic leukemia in post-chemotherapy patients receiving G-CSF: report of two cases
Liu, C Z; Persad, R; Inghirami, G; Sen, F; Amorosi, E; Goldenberg, A; Ibrahim, S
2004 Oct;26(5):359-362, Clinical & laboratory haematology
— id: 45370, year: 2004, vol: 26, page: 359, stat: Journal Article,

Bone marrow biopsy (bmb) needle (ndl) selection and specimen (sp) adequacy
Goldenberg, A; Kelley, P; Ibrahim, S; Sen, F; Inghirami, G
2003 NOV 16 ;102(11):753A-753A, Blood
— id: 42499, year: 2003, vol: 102, page: 753A, stat: Journal Article,

Recovery of large bone marrow core specimens
Goldenberg, A; Kelley, P; Ibrahim, S; Sen, F; Inghirami, G
2003 NOV 16 ;102(11):750A-750A, Blood
— id: 42498, year: 2003, vol: 102, page: 750A, stat: Journal Article,

Significance of elevated CD4/CD8 ratio in flow cytometry studies of nodal FNA material
Hernandez, O; Oweity, T; Inghirami, G; Ibrahim, S
2003 ;83(Suppl 1):68A-69A, Laboratory investigation
— id: 37145, year: 2003, vol: 83, page: 68A, stat: Journal Article,

Clinical relevance of the expression of the CD31 ligand for CD38 in patients with B-cell chronic lymphocytic leukemia
Ibrahim, Sherif; Jilani, Iman; O'Brien, Susan; Rogers, Anna; Manshouri, Taghi; Giles, Francis; Faderl, Stefan; Thomas, Deborah; Kantarjian, Hagop; Keating, Michael; Albitar, Maher
2003 Apr 15;97(8):1914-1919, Cancer
— id: 95599, year: 2003, vol: 97, page: 1914, stat: Journal Article,

S-phase kinase associatd protein 2 is an objective tool for grading follicular lymphoma
Liu, CZ; Persad, R; Fan, Y; Chiarle, R; Ibrahim, S; Inghirami, G
2003 ;16(Suppl 1):242A-243A, Modern pathology
— id: 38532, year: 2003, vol: 16, page: 242A, stat: Journal Article,

S-phase kinase associated protein 2 is an objective tool for grading follicular lymphoma
Liu, CZ; Persad, R; Fan, Y; Chiarle, R; Ibrahim, S; Inghirami, G
2003 ;83(Suppl 1):242A-243A, Laboratory investigation
— id: 37161, year: 2003, vol: 83, page: 242A, stat: Journal Article,

Immunophenotypic changes commonly occur in relapsed acute myelogenous leukemia, as detected by multi-color flow cytometry using a selected panel of antibodies
Persad, R; Liu, CZ; Ibrahim, S; Inghirami, G
2003 ;83(Suppl 1):248A-248A, Laboratory investigation
— id: 37162, year: 2003, vol: 83, page: 248A, stat: Journal Article,

Immunophenotypic changes commonly occur in relapsed acute myelogenous leukemia, as detected by multi-color flow cytometry using a selected panel of antibodies
Persad, R; Liu, CZ; Ibrahim, S; Inghirami, G
2003 ;16(Suppl 1):248A-248A, Modern pathology
— id: 38533, year: 2003, vol: 16, page: 248A, stat: Journal Article,

Prevention of chronic rejection with immunoregulatory cells induced by intrathymic immune modulation with class I allopeptides
Shirwan, Haval; Mhoyan, Anna; Kakoulidis, Thanos P; Yolcu, Esma S; Ibrahim, Sherif
2003 May;3(5):581-589, American journal of transplantation
— id: 95598, year: 2003, vol: 3, page: 581, stat: Journal Article,

Chronic cardiac allograft rejection in a rat model disparate for one single class I MHC molecule is associated with indirect recognition by CD4(+) T cells
Shirwan, Haval; Mhoyan, Anna; Yolcu, Esma S; Que, Xingyi; Ibrahim, Sherif
2003 Apr-Jun;11(2):179-185, Transplant immunology
— id: 95597, year: 2003, vol: 11, page: 179, stat: Journal Article,

Myeloid disorders with deletion of 5q as the sole karyotypic abnormality: the clinical and pathologic spectrum
Washington, LaBaron T; Doherty, Dorota; Glassman, Armand; Martins, Joseph; Ibrahim, Sherif; Lai, Raymond
2002 Apr;43(4):761-765, Leukemia & lymphoma
— id: 95600, year: 2002, vol: 43, page: 761, stat: Journal Article,