Biosketch / Results /

John Graham Hay, M.D.

Associate Professor; Sec Ch Pulmonary& Critical Medicine VA
Departments of Medicine (Pulmy&CCM Div) and Pathology (Pathology)

Clinical Addresses

NYU Trinity Centre
111 BROADWAY
NEW YORK, NY 10006
Handicap Access: yes
Phone: 212-263-9700

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Medical Specialties

Pulmonary Medicine

Medical Expertise

Pulmonary Fibrosis, Chronic Obstructive Pulmonary Disorder (COPD), Asthma, Tuberculosis, Emphysema, Pulmonary Hypertension, Interstitial Lung Disease, Occupational/Environmental Lung Disease, Hypoventilation, Sarcoidosis, Pulmonary Function Testing, Carcinoma of the Lung, Atypical Mycobacterial Diseases, Chronic Bronchitis, Lung Cancer, Bronchiectasis, Abnormal CT Scans, Chronic Respiratory Failure

Insurance

AETNA HMO, AETNA INDEMNITY, AETNA MEDICARE, AETNA POS, AETNA PPO/EPO, AFFINITY, AFFINITY EXCHANGE- ESSENTIAL, CIGNA EPO/POS, Cigna PPO, EBCBS EPO, EBCBS HLTHY NY, EBCBS HMO, EBCBS INDEMNITY, EBCBS MEDIBLUE, EBCBS POS, EBCBS PPO, ELDERPLAN, GHI CBP, HEALTHPLUS CHLD HLTH (AMERIGROUP), HEALTHPLUS FAM HLTH (AMERIGROUP), HEALTHPLUS MEDICAID (AMERIGROUP), HEALTHREPUBLIC, HIP ACCESS I, HIP ACCESS II, HIP CHLD HLTH, HIP EPO/PPO, HIP FAM HLTH, HIP HMO, HIP MEDICAID, HIP MEDICARE, HIP POS, MAGNACARE PPO, MULTIPLAN/PHCS PPO, Medicare, NY MEDICAID, NYS EMPIRE PLAN, OSCAR, OXFORD EXCHANGE, OXFORD FREEDOM, Oxford Liberty, Oxford Medicare, Tricare, UHC COMMUNITY & STATE PLAN, UHC EPO, UHC HMO, UHC MEDICARE, UHC POS, UHC PPO, UHC TOP TIER, UNITED EXCHANGE- COMPASS WELLCARE CHLD HLTH, WELLCARE FAM HLTH, WELLCARE MEDICAID, WELLCARE MEDICARE

Insurance Disclaimer: Insurance listed above may not be accepted at all office locations. Please confirm prior to each visit. The information presented here may not be complete or may have changed.

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Board Certification

2006 — Ab Internal Medicine - Internal Medicine
2007 — Ab Internal Medicine (Pulmonary Disease)

Education

1975-1978 — University of London Kings College, Medical Education
1979-1980 — Kings College Hospital (Medicine), Internship
1980-1982 — King's College Hospital and Brook Hospital (Medicine), Residency Training

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

A novel cell-penetrating peptide to facilitate intercellular transport of fused proteins
Shen, Ying; Nagpal, Poonam; Hay, John G; Sauthoff, Harald
2014 Jun;:50-50, Journal of controlled release
— id: 1036472, year: 2014, vol: , page: 50, stat: Journal Article,

Interventions to stabilize endothelium improve survival in experimental cerebral Malaria
Higgins, S J; Silver, K L; Hay, J G; Robinson, L A; Liles, W C; Kain, K C
2012 November 2012;87(5):439-439, American journal of tropical medicine & hygiene
— id: 335032, year: 2012, vol: 87, page: 439, stat: Journal Article,

A novel protein transduction domain with improved secretion and transduction activity
Shen Y.; Yu W.; Nagpal P.; Hay J.G.; Sauthoff H.
2011 ;19:S160-S160, Molecular therapy
— id: 134516, year: 2011, vol: 19, page: S160, stat: Journal Article,

Expressed Cell-penetrating Peptides Can Induce a Bystander Effect, but Passage Through the Secretory Pathway Reduces Protein Transduction Activity
Shen, Ying; Yu, William; Hay, John G; Sauthoff, Harald
2011 May;19(5):903-912, Molecular therapy
— id: 131954, year: 2011, vol: 19, page: 903, stat: Journal Article,

Illness-related distress in women with clinically localized cutaneous melanoma
Noce N.S.; Atkinson T.M.; Hay J.; Rafferty B.; Brady M.S.
2010 ;23(6):966-967, Pigment cell & melanoma research
— id: 135618, year: 2010, vol: 23, page: 966, stat: Journal Article,

Relative angiopoietin levels alter susceptibility to experimental cerebral malaria
Silver K.L.; Higgins S.; Hay J.G.; Quaggin S.E.; Conrad Liles W.; Kain K.C.
2010 ;83(5 SUPPL 1):163-163, American journal of tropical medicine & hygiene
— id: 134757, year: 2010, vol: 83, page: 163, stat: Journal Article,

Angiopoietin-1 increases survival and reduces the development of lung edema induced by endotoxin administration in a murine model of acute lung injury
Huang, Yao Qi; Sauthoff, Harald; Herscovici, Pablo; Pipiya, Teona; Cheng, Jin; Heitner, Sheila; Szentirmai, Oskar; Carter, Bob; Hay, John G
2008 Jan;36(1):262-267, Critical care medicine
— id: 75847, year: 2008, vol: 36, page: 262, stat: Journal Article,

How do changes in tumor matrix affect the outcome of virotherapy?
Cheng, Jin; Sauthoff, Harald; Hay, John G
2007 Feb;6(2):290-292, Cancer biology & therapy
— id: 73800, year: 2007, vol: 6, page: 290, stat: Journal Article,

Human matrix metalloproteinase-8 gene delivery increases the oncolytic activity of a replicating adenovirus
Cheng, Jin; Sauthoff, Harald; Huang, YaoQi; Kutler, David I; Bajwa, Sofia; Rom, William N; Hay, John G
2007 Nov;15(11):1982-1990, Molecular therapy
— id: 75471, year: 2007, vol: 15, page: 1982, stat: Journal Article,

Sindbis. Virus Expression Vectors
Hay JG; Herscovici P
Virus expression vectors Karala, India : Transworld Research Network, 2007,
— id: 5771, year: 2007, vol: , page: 180, stat: Chapter,

Molecular biology
Hay, John G
Environmental and occupational medicine Philadelphia : Wolters Kluwer/Lippincott Williams & Wilkins, 2007,
— id: 5365, year: 2007, vol: , page: ?, stat: Chapter,

Modification of the p53 transgene of a replication-competent adenovirus prevents mdm2- and E1b-55kD-mediated degradation of p53
Sauthoff, H; Pipiya, T; Chen, S; Heitner, S; Cheng, J; Huang, Y Q; Rom, W N; Hay, J G
2006 Jul;13(7):686-695, Cancer gene therapy
— id: 67944, year: 2006, vol: 13, page: 686, stat: Journal Article,

Drug evaluation: Reolysin--wild-type reovirus as a cancer therapeutic
Stoeckel, Jessica; Hay, John G
2006 Jun;8(3):249-260, Current opinion in molecular therapeutics
— id: 70972, year: 2006, vol: 8, page: 249, stat: Journal Article,

The potential impact of hypoxia on the success of oncolytic virotherapy
Hay, John G
2005 Aug;7(4):353-358, Current opinion in molecular therapeutics
— id: 61256, year: 2005, vol: 7, page: 353, stat: Journal Article,

Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression
Pipiya, T; Sauthoff, H; Huang, Y Q; Chang, B; Cheng, J; Heitner, S; Chen, S; Rom, W N; Hay, J G
2005 Jun;12(11):911-917, Gene therapy
— id: 57889, year: 2005, vol: 12, page: 911, stat: Journal Article,

Sindbis virus--an effective targeted cancer therapeutic
Hay, John G
2004 Oct;22(10):501-503, Trends in biotechnology
— id: 48102, year: 2004, vol: 22, page: 501, stat: Journal Article,

Angiopoietin-1 reduces lung edema and mortality induced by bacterial endotoxin
Huang, YQ; Sauthoff, H; Pipiya, T; Chen, S; Rom, WN; Hay, JG
2004 MAY ;9(1-2):S262-S262, Molecular therapy
— id: 46544, year: 2004, vol: 9, page: S262, stat: Journal Article,

Hypoxia reduces adenoviral replication in cancer cells by down-regulation of viral protein expression
Pipiya, T; Sauthoff, H; Huang, YQ; Chang, B; Rom, WN; Hay, JG
2004 MAY ;9(1-2):S106-S107, Molecular therapy
— id: 46542, year: 2004, vol: 9, page: S106, stat: Journal Article,

Modification of the p53 transgene of a replication-competent adenovirus improves p53 stability and cancer cell killing
Sauthoff, H; Pipiya, T; Chen, S; Heitner, S; Huang, YQ; Rom, WN; Hay, JG
2004 MAY ;9(1-2):S112-S112, Molecular therapy
— id: 46543, year: 2004, vol: 9, page: S112, stat: Journal Article,

Impact of E1a modifications on tumor-selective adenoviral replication and toxicity
Sauthoff, Harald; Pipiya, Teona; Heitner, Sheila; Chen, Shu; Bleck, Bertram; Reibman, Joan; Chang, William; Norman, Robert G; Rom, William N; Hay, John G
2004 Oct;10(4):749-757, Molecular therapy
— id: 156544, year: 2004, vol: 10, page: 749, stat: Journal Article,

Essentials of medical genomics
Brown, Stuart M; Hay, John G; Ostrer, Harry
Hoboken NJ : Wiley-Liss, 2003,
— id: 899, year: 2003, vol: , page: , stat: ,

"Man's best friend": a new model system for cancer therapeutics?
Hay, John G
2003 Feb;7(2):144-145, Molecular therapy
— id: 44923, year: 2003, vol: 7, page: 144, stat: Journal Article,

Hypoxia reduces adenoviral replication in cancer cells
Pipiya, T; Sauthoff, H; Heitner, S; Chen, S; Rom, W; Hay, JG
2003 MAY ;7(5):S174-S175, Molecular therapy
— id: 38566, year: 2003, vol: 7, page: S174, stat: Journal Article,

Comparison of E1a modifications to achieve tumor cell selective viral replication and toxicity
Sauthoff, H; Pipiya, T; Heitner, S; Chang, W; Chen, S; Rom, WN; Hay, JG
2003 MAY ;7(5):S453-S454, Molecular therapy
— id: 38567, year: 2003, vol: 7, page: S453, stat: Journal Article,

Intratumoral spread of wild-type adenovirus is limited after local injection of human xenograft tumors: virus persists and spreads systemically at late time points
Sauthoff, Harald; Hu, Jing; Maca, Cielo; Goldman, Michael; Heitner, Sheila; Yee, Herman; Pipiya, Teona; Rom, William N; Hay, John G
2003 Mar 20;14(5):425-433, Human gene therapy
— id: 37579, year: 2003, vol: 14, page: 425, stat: Journal Article,

Glucocorticoids inhibit lung cancer cell growth through both the extracellular signal-related kinase pathway and cell cycle regulators
Greenberg, Alissa K; Hu, Jing; Basu, Sharmila; Hay, John; Reibman, Joan; Yie, Ting-An; Tchou-Wong, Kam Meng; Rom, William N; Lee, Theodore C
2002 Sep;27(3):320-328, American journal of respiratory cell & molecular biology
— id: 39599, year: 2002, vol: 27, page: 320, stat: Journal Article,

Recollection memory deficits in patients with major depressive disorder predicted by past depressions but not current mood state or treatment status
MacQueen, G M; Galway, T M; Hay, J; Young, L T; Joffe, R T
2002 Feb;32(2):251-258, Psychological medicine
— id: 139188, year: 2002, vol: 32, page: 251, stat: Journal Article,

Late expression of p53 from a replicating adenovirus improves tumor cell killing and is more tumor cell specific than expression of the adenoviral death protein
Sauthoff, Harald; Pipiya, Teona; Heitner, Sheila; Chen, Shu; Norman, Robert G; Rom, William N; Hay, John G
2002 Oct;13(15):1859-1871, Human gene therapy
— id: 156046, year: 2002, vol: 13, page: 1859, stat: Journal Article,

Wild-type adenovirus decreases tumor xenograft growth, but despite viral persistence complete tumor responses are rarely achieved-deletion of the viral e1b-19-kd gene increases the viral oncolytic effect
Harrison D; Sauthoff H; Heitner S; Jagirdar J; Rom WN; Hay JG
2001 Jul;12(10):1323-1332, Human gene therapy
— id: 21145, year: 2001, vol: 12, page: 1323, stat: Journal Article,

Hut lung. A domestically acquired particulate lung disease [In Process Citation]
Gold JA; Jagirdar J; Hay JG; Addrizzo-Harris DJ; Naidich DP; Rom WN
2000 Sep;79(5):310-317, Medicine (Baltimore)
— id: 15397, year: 2000, vol: 79, page: 310, stat: Journal Article,

Molecular and genetic aspects of lung cancer
Rom WN; Hay JG; Lee TC; Jiang Y; Tchou-Wong KM
2000 Apr;161(4 Pt 1):1355-1367, American journal of respiratory & critical care medicine
— id: 11754, year: 2000, vol: 161, page: 1355, stat: Journal Article,

Deletion of the adenoviral E1b-19kD gene enhances tumor cell killing of a replicating adenoviral vector
Sauthoff H; Heitner S; Rom WN; Hay JG
2000 Feb 10;11(3):379-388, Human gene therapy
— id: 8543, year: 2000, vol: 11, page: 379, stat: Journal Article,

Replicating adenoviral vectors persist in tumor xenographs for up to 100 days but viral spread is insufficient to support tumor eradication
Sauthoff, H; Harrison, D; Heitner, S; Rom, WN; Hay, JG
2000 DEC ;7(12):S13-S14, Cancer gene therapy
— id: 54416, year: 2000, vol: 7, page: S13, stat: Journal Article,

Targeting the replication of adenoviral gene therapy vectors to lung cancer cells: the importance of the adenoviral E1b-55kD gene
Hay JG; Shapiro N; Sauthoff H; Heitner S; Phupakdi W; Rom WN
1999 Mar 1;10(4):579-590, Human gene therapy
— id: 7342, year: 1999, vol: 10, page: 579, stat: Journal Article,

Deletion of the E1b-19-kDa gene enhances the tumoricidal effect of a replicating adenoviral vector
Sauthoff K; Heitner S; Rom WN; Hay JG
1999 Nov-Dec;6(6 Suppl S):S10-S10 Abstract #O38, Cancer gene therapy
— id: 8605, year: 1999, vol: 6, page: S10, stat: Journal Article,

An E1b-55kD deleted adenovirus vector does not target p53 mutated lung cancer cells by specific viral replication
Sauthoff, H; Shapiro, N; Heitner, S; Phupakdi, W; Rom, WN; Hay, JG
1999 MAR ;159(3):A237-A237, American journal of respiratory & critical care medicine
— id: 53872, year: 1999, vol: 159, page: A237, stat: Journal Article,