Kathleen Ann Haines

Biosketch / Results /

Kathleen Ann Haines, M.D.

Adjunct Associate Professor;
Departments of Medicine (Medicine), Hospital for Joint Diseases and Pediatrics (General Med-HJD )

Clinical Addresses

HACKENSACK UNIVERSITY MED CTR
30 PROSPECT AVENUE
HACKENSACK, NJ 07601
Hours: Tue. 9 - 4:30; Wed. 9 - 4:30; Fri. 9 - 11:30
Phone: 201-996-5306
Fax: 201-996-9815

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Medical Specialties

Pediatrics, Pediatric Rheumatology

Medical Expertise

Pediatric Rheumatology

Languages

Spanish

Insurance

AETNA HMO, AETNA INDEMNITY, AETNA MEDICARE, AETNA POS, AETNA PPO, Aetna EPO, Cigna EPO, Cigna HMO, Cigna Indemnity, Cigna POS, Cigna PPO, Empire BCBS Child Health Plus, Empire BCBS EPO, Empire BCBS HMO, Empire BCBS Healthy NY, Empire BCBS Indemnity, Empire BCBS POS, Empire BCBS PPO, HEALTHREPUBLIC, MAGNACARE PPO, Medicare, Multiplan, OSCAR, Oxford Freedom Plan, Oxford Medicare, Private Healthcare Systems (PHCS), Tricare, UHC EPO, UHC HMO, UHC POS, UHC PPO, UHC TOP TIER

Insurance Disclaimer: Insurance listed above may not be accepted at all office locations. Please confirm prior to each visit. The information presented here may not be complete or may have changed.

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Board Certification

1980 — Ab Pediatrics - Pediatrics
1981 — Ab Allergy & Immunology (Clinical & Laboratory Immunology)
1981 — Ab Allergy & Immunology - Allergy & Immunology
2007 — Ab Pediatrics (Pediatric Rheumatology)

Education

1975 — Albert Einstein College of Medicine, Medical Education
1975-1976 — New York Presbyterian - Weill Cornell Medical Center (Pediatics), Internship
1976-1977 — New York Presbyterian - Weill Cornell Medical Center (Pediatrics), Residency Training
1977-1980 — New York Presbyterian - Weill Cornell Medical Center (Allergy & Immunology), Clinical Fellowships
1980-1982 — NYU Medical Center (Rheumatology), Clinical Fellowships

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Research Summary

A critical host defense mechanism in response to bacterial infection or tissue injury is an influx of polymorphonuclear neutrophilic leukocytes, or neutrophils, to the affected area. Once at the inflamed site, the neutrophils ingest, or phagocytose, bacteria or damaged tissue and release toxic oxygen metabolites (O2H2O2) and proteolytic enzymes to digest the phagocytosed material. Activation of these neutrophils is initiated by local production of compounds known as chemoattractants, either by the body or the invading bacteria. Similarly, bacteria that have been "tagged" by antibodies binding to their surface also provoke activation of neutrophils. However, in autoimmune diseases in which the body "tags" its own tissue with antibodies, this response becomes pathologic as the neutrophils trigger inappropriate inflammation.

We study the intracellular signals produced by neutrophils after activation by chemoattractants, aggregated immune complexes, and antibody-coated particles. We have used a unique protein produced by Neisseria gonorrhoea (Por) as a probe to dissect which signals are requried for the idscrete responses of chemotaxis, O2 generation, and lysosomal enzyme release. Pretreatment of neutrophils with Por inhibits the release of granule enzymes triggered by chemoattractants and, in parallel, inhibits the production of the diglyceride class of second messengers. Interestingly, Por does not inhibit neutrophil function triggered by immune complexes thus indicating that chemoattractants and immune complexes activate different signaling pahtways. We continue to examine the relationship of other signals such as protein kinases, phosphatases, and lipid products to neutrophil function in bacterial infection and pathologic inflammation to help us understand and control this important aspect of both health and disease.

Research Interests

Mechanisms of Inflammation in Health and Disease

Research Keywords

autoimmunity, bacterial pathogenesis, inflammation, neutrophils, signal transduction

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

A22: consensus treatment plans for induction therapy in childhood proliferative lupus nephritis-status of use in daily clinical care
von Scheven, Emily; Punaro, Marilynn; Ardoin, Stacy P; Brunner, Hermine; Hsu, Joyce J; Mehta, Jay; Wagner-Weiner, Linda; Klein-Gitelman, Marisa; Rouster Stevens, Kelly; Haines, Kathleen A; Schanberg, Laura; Eberhard, B Anne
2014 Mar;66 Suppl 11:S35-S36, Arthritis & rheumatology
— id: 921252, year: 2014, vol: 66 Suppl 11, page: S35, stat: Journal Article,

Cancer risk in childhood-onset systemic lupus
Bernatsky, Sasha; Clarke, Ann E; Labrecque, Jeremy; von Scheven, Emily; Schanberg, Laura E; Silverman, Earl D; Brunner, Hermine I; Haines, Kathleen A; Cron, Randy Q; O'Neil, Kathleen M; Oen, Kiem; Rosenberg, Alan M; Duffy, Ciaran M; Joseph, Lawrence; Lee, Jennifer L; Kale, Mruganka; Turnbull, Elizabeth M; Ramsey-Goldman, Rosalind
2013 ;15(6):R198-R198 R198, Arthritis research & therapy
— id: 921242, year: 2013, vol: 15, page: R198, stat: Journal Article,

Consensus treatments for moderate Juvenile Dermatomyositis: Beyond the first two months. Results of the Second Childhood Arthritis and Rheumatology Research Alliance Consensus Conference
Huber, Adam M; Robinson, Angela B; Reed, Ann M; Abramson, Leslie; Bout-Tabaku, Sharon; Carrasco, Ruy; Curran, Megan; Feldman, Brian M; Gewanter, Harry; Griffin, Thomas; Haines, Kathleen; Hoeltzel, Mark F; Isgro, Josephine; Kahn, Philip; Lang, Bianca; Lawler, Patti; Shaham, Bracha; Schmeling, Heinrike; Scuccimarri, Rosie; Shishov, Michael; Stringer, Elizabeth; Wohrley, Julie; Ilowite, Norman T; Wallace, Carol
2012 Apr;64(4):546-553, Arthritis care & research (2010)
— id: 164402, year: 2012, vol: 64, page: 546, stat: Journal Article,

Treatment of pediatric localized scleroderma: results of a survey of North American pediatric rheumatologists
Li, Suzanne C; Feldman, Brian M; Higgins, Gloria C; Haines, Kathleen A; Punaro, Marilynn G; O'Neil, Kathleen M
2010 Jan;37(1):175-181, Journal of rheumatology
— id: 921232, year: 2010, vol: 37, page: 175, stat: Journal Article,

Neutrophil gelatinase-associated lipocalin is a predictor of the course of global and renal childhood-onset systemic lupus erythematosus disease activity
Hinze, Claas H; Suzuki, Michiko; Klein-Gitelman, Marisa; Passo, Murray H; Olson, Judyann; Singer, Nora G; Haines, Kathleen A; Onel, Karen; O'Neil, Kathleen; Silverman, Earl D; Tucker, Lori; Ying, Jun; Devarajan, Prasad; Brunner, Hermine I
2009 Sep;60(9):2772-2781, Arthritis & rheumatism
— id: 921222, year: 2009, vol: 60, page: 2772, stat: Journal Article,

Neutrophil gelatinase-associated lipocalin as a biomarker of disease activity in pediatric lupus nephritis
Suzuki, Michiko; Wiers, Kristina M; Klein-Gitelman, Marisa S; Haines, Kathleen A; Olson, Judyann; Onel, Karen B; O'Neil, Kathleen; Passo, Murray H; Singer, Nora G; Tucker, Lori; Ying, Jun; Devarajan, Prasad; Brunner, Hermine I
2008 Mar;23(3):403-412, Pediatric nephrology
— id: 96584, year: 2008, vol: 23, page: 403, stat: Journal Article,

Juvenile idiopathic arthritis: therapies in the 21st century
Haines, Kathleen A
2007 ;65(3):205-211, Bulletin of the NYU Hospital for Joint Diseases
— id: 75661, year: 2007, vol: 65, page: 205, stat: Journal Article,

The effect of moderate-dose corticosteroids in preventing severe flares in patients with serologically active, but clinically stable, systemic lupus erythematosus: Findings of a prospective, randomized, double-blind, placebo-controlled trial
Tseng, Chung-E; Buyon, Jill P; Kim, Mimi; Belmont, H Michael; Mackay, Meggan; Diamond, Betty; Marder, Galina; Rosenthal, Pamela; Haines, Kathleen; Ilie, Virginia; Abramson, Steven B
2006 Oct 30;54(11):3623-3632, Arthritis & rheumatism
— id: 69280, year: 2006, vol: 54, page: 3623, stat: Journal Article,

Moderate dose steroids prevent severe flares in a prospective Multicenter study of serologically active, clinically stable systemic lupus erythematosus (SLE) patients
Tseng, C; Buyon, J; Kim, M; Belmont, HM; Mackay, M; Diamond, B; Marder, G; Rosenthal, P; Haines, K; Abramson, S
2003 SEP ;48(9):S260-S261, Arthritis & rheumatism
— id: 55436, year: 2003, vol: 48, page: S260, stat: Journal Article,

Preoperative identification of a bone-cement allergy in a patient undergoing total knee arthroplasty
Kaplan, Kevin; Della Valle, Craig J; Haines, Kathleen; Zuckerman, Joseph D
2002 Sep;17(6):788-791, Journal of arthroplasty
— id: 44552, year: 2002, vol: 17, page: 788, stat: Journal Article,

C3, C4, CH50, anti-dsDNA antibodies and C3a complement split products are specific but not sensitive for predicting flares of systemic lupus (SLE)
Tseng, CE; Abramson, SB; Kim, M; Blemont, HM; Haines, K; Petri, M; Buyon, JP
2002 SEP ;46(9):S214-S214, Arthritis & rheumatism
— id: 37119, year: 2002, vol: 46, page: S214, stat: Journal Article,

Neutrophils (PMM) and inflammation: immune complexes (1C) and bacterial stimuli each trigger distinct functions and intracellular signals
Haines, KA; Ou, G
1996 ;44(3):-, Journal of investigative medicine
— id: 564892, year: 1996, vol: 44, page: , stat: Journal Article,

Neutrophils (PMN) and inflammation: Immune complexes (IC) and bacterial stimuli each trigger distinct functions and intracellular signals
Haines, KA; Ou, G
1996 MAR ;44(3):A294-A294, Journal of investigative medicine
— id: 52964, year: 1996, vol: 44, page: A294, stat: Journal Article,

Signal transduction in neutrophils (PMN): Adenosine inhibits and augments protein phosphatidase activity in PMN cytosol
Haines, KA; Ou, GM; Montesinos, MC; Cronstein, BN
1996 SEP ;39(9):63-63, Arthritis & rheumatism
— id: 52777, year: 1996, vol: 39, page: 63, stat: Journal Article,

Rapid oral desensitization to trimethoprim-sulfamethoxazole in infants and children
Palusci VJ; Kaul A; Lawrence RM; Haines KA; Kwittken PL
1996 May;15(5):456-460, Pediatric infectious disease journal
— id: 7086, year: 1996, vol: 15, page: 456, stat: Journal Article,

PHAGOCYTOSIS BY NEUTROPHILS REQUIRES A SIGNAL-TRANSDUCTION PATHWAY DISTINCT FROM OTHER FUNCTIONS
HAINES, KA; OU, G
1995 SEP ;38(9):233-233, Arthritis & rheumatism
— id: 86688, year: 1995, vol: 38, page: 233, stat: Journal Article,

SIGNAL-TRANSDUCTION IN NEUTROPHILS - PHOSPHATIDATE IS NOT REQUIRED FOR SUPEROXIDE (O-2(TAU)) GENERATION
HAINES, KA; MIRABILE, E; OU, G
1994 APR ;42(2):A113-A113, Clinical research
— id: 52482, year: 1994, vol: 42, page: A113, stat: Journal Article,

Immunocomplexes stimulate different signalling events to chemoattractants in the neutrophil and regulate L-selectin and beta 2-integrin expression differently
Molad Y; Haines KA; Anderson DC; Buyon JP; Cronstein BN
1994 May 1;299(Pt 3):881-887, Biochemical journal
— id: 6462, year: 1994, vol: 299, page: 881, stat: Journal Article,

Chemoattraction of neutrophils by substance P and transforming growth factor-beta 1 is inadequately explained by current models of lipid remodeling
Haines KA; Kolasinski SL; Cronstein BN; Reibman J; Gold LI; Weissmann G
1993 Aug 1;151(3):1491-1499, Journal of immunology (1950)
— id: 9821, year: 1993, vol: 151, page: 1491, stat: Journal Article,

IMMUNE-COMPLEXES (IC) AND CHEMOATTRACTANTS (IL-8, C5A AND FMLP) DIFFERENTIALLY MODULATE INTEGRIN AND SELECTIN EXPRESSION ON NEUTROPHILS (PMNS)
HAINES, KA; MOLAD, Y; ANDERSON, DC; BUYON, JP; CRONSTEIN, BN
1993 APR ;41(2):A278-A278, Clinical research
— id: 54273, year: 1993, vol: 41, page: A278, stat: Journal Article,

NITRIC-OXIDE DERIVATIVE, S-NITROSOGLUTATHIONE, BLOCKS IL-2 DEPENDENT DNA-SYNTHESIS VIA INHIBITION OF RIBONUCLEOTIDE REDUCTASE-ACTIVITY IN HUMAN T-CELLS
MERRYMAN, PF; CLANCY, RM; HAINES, KA; HE, Y; ABRAMSON, SB
1993 SEP ;36(9):S113-S113, Arthritis & rheumatism
— id: 52191, year: 1993, vol: 36, page: S113, stat: Journal Article,

Stimulus-response uncoupling in the neutrophil. Adenosine A2-receptor occupancy inhibits the sustained, but not the early, events of stimulus transduction in human neutrophils by a mechanism independent of actin-filament formation
Cronstein BN; Haines KA
1992 Feb 1;281(Pt 3):631-635, Biochemical journal
— id: 9829, year: 1992, vol: 281, page: 631, stat: Journal Article,

Occupancy of G alpha s-linked receptors uncouples chemoattractant receptors from their stimulus-transduction mechanisms in the neutrophil
Cronstein BN; Haines KA; Kolasinski S; Reibman J
1992 Aug 15;80(4):1052-1057, Blood
— id: 9826, year: 1992, vol: 80, page: 1052, stat: Journal Article,

SIGNAL TRANSDUCTION IN NEUTROPHILS - ACTIVATION OF PHOSPHOLIPASES IS NEITHER NECESSARY NOR SUFFICIENT FOR CHEMOTAXIS
HAINES, KA; CRONSTEIN, BN; REIBMAN, J; WEISSMANN, G
1992 APR ;40(2):A249-A249, Clinical research
— id: 51990, year: 1992, vol: 40, page: A249, stat: Journal Article,

CHEMOATTRACTION OF NEUTROPHILS BY SUBSTANCE-P AND TRANSFORMING GROWTH FACTOR-BETA-1 SHOWS THAT CURRENT MODELS OF LIPID REMODELING ARE INADEQUATE
HAINES, KA; TANG, XY; KOLASINSKI, SL; CRONSTEIN, BN; REIBMAN, J; WEISSMANN, G
1992 SEP ;35(9):S42-S42, Arthritis & rheumatism
— id: 51841, year: 1992, vol: 35, page: S42, stat: Journal Article,

Neuropeptides and inflammation. A somatostatin analog as a selective antagonist of neutrophil activation by substance P
Kolasinski SL; Haines KA; Siegel EL; Cronstein BN; Abramson SB
1992 Apr;35(4):369-375, Arthritis & rheumatism
— id: 9750, year: 1992, vol: 35, page: 369, stat: Journal Article,

Non-steroidal anti-inflammatory drugs: effects on a GTP binding protein within the neutrophil plasma membrane
Abramson SB; Leszczynska-Piziak J; Haines K; Reibman J
1991 Jun 1;41(11):1567-1573, Biochemical pharmacology
— id: 9756, year: 1991, vol: 41, page: 1567, stat: Journal Article,

Effects of protein I of Neisseria gonorrhoeae on neutrophil activation: generation of diacylglycerol from phosphatidylcholine via a specific phospholipase C is associated with exocytosis
Haines KA; Reibman J; Tang XY; Blake M; Weissmann G
1991 Aug;114(3):433-442, Journal of cell biology
— id: 13948, year: 1991, vol: 114, page: 433, stat: Journal Article,

Protein I of N. gonorrhoeae shows that phosphatidate from phosphatidylcholine via phospholipase C is an intracellular messenger in neutrophil activation by chemoattractants
Haines KA; Weissmann G
1991 ;21B:545-552, Advances in prostaglandin thromboxane & leukotriene research
— id: 14198, year: 1991, vol: 21B, page: 545, stat: Journal Article,

PROTEIN-I OF N-GONORRHEA PERMITS DISTINCTION BETWEEN G-PROTEIN DEPENDENT NEUTROPHIL RESPONSES
HAINES, KA; TANG, XY; WEISSMANN, G
1991 APR ;29(4):A173-A173, Pediatric research
— id: 51665, year: 1991, vol: 29, page: A173, stat: Journal Article,

PROTEIN-I OF N-GONORRHEA SHOWS THAT PHOSPHATIDATE FROM PHOSPHATIDYLCHOLINE VIA PHOSPHOLIPASE-C IS AN INTRACELLULAR MESSENGER IN NEUTROPHIL ACTIVATION BY CHEMOATTRACTANTS
HAINES, KA; WEISSMANN, G
1991 JAN ;21(1):545-552, Advances in prostaglandin & thromboxane research
— id: 51751, year: 1991, vol: 21, page: 545, stat: Journal Article,

THE CHEMOATTRACTANT FAMILY - ANTAGONISM OF SUBSTANCE-P, BUT NOT OTHER CHEMOATTRACTANTS, BY SOMATOSTATIN
KOLASINSKI, SL; HAINES, KA; SIEGEL, EL; CRONSTEIN, BN; ABRAMSON, SB
1991 APR ;39(2):A258-A258, Clinical research
— id: 51609, year: 1991, vol: 39, page: A258, stat: Journal Article,

Low molecular weight GTP-binding proteins in human neutrophil granule membranes
Philips MR; Abramson SB; Kolasinski SL; Haines KA; Weissmann G; Rosenfeld MG
1991 Jan 15;266(2):1289-1298, Journal of biological chemistry
— id: 8314, year: 1991, vol: 266, page: 1289, stat: Journal Article,

Differences in signal transduction between Fc gamma receptors (Fc gamma RII, Fc gamma RIII) and FMLP receptors in neutrophils. Effects of colchicine on pertussis toxin sensitivity and diacylglycerol formation
Reibman J; Haines KA; Gude D; Weissmann G
1991 Feb 1;146(3):988-996, Journal of immunology (1950)
— id: 14149, year: 1991, vol: 146, page: 988, stat: Journal Article,

Transforming growth factor beta 1, a potent chemoattractant for human neutrophils, bypasses classic signal-transduction pathways
Reibman J; Meixler S; Lee TC; Gold LI; Cronstein BN; Haines KA; Kolasinski SL; Weissmann G
1991 Aug 1;88(15):6805-6809, Proceedings of the National Academy of Sciences of the United States of America
— id: 9831, year: 1991, vol: 88, page: 6805, stat: Journal Article,

ADENOSINE-A2 RECEPTOR OCCUPANCY DOES NOT AFFECT TRIGGERING BUT INHIBITS ACTIVATION OF HUMAN NEUTROPHILS (PMN) BY A MECHANISM INDEPENDENT OF ACTIN-FILAMENTS
Cronstein, BN; Haines, KA
1990 Apr;38(2):A554-A554, Clinical research
— id: 31971, year: 1990, vol: 38, page: A554, stat: Journal Article,

Cocaine and its derivatives blunt neutrophil functions without influencing phosphorylation of a 47-kilodalton component of the reduced nicotinamide-adenine dinucleotide phosphate oxidase
Haines KA; Reibman J; Callegari PE; Abramson SB; Philips MR; Weissmann G
1990 Jun 15;144(12):4757-4764, Journal of immunology (1950)
— id: 9758, year: 1990, vol: 144, page: 4757, stat: Journal Article,

SODIUM-FLUORIDE (NAF) DEMONSTRATES DIVERGENT SIGNALING MECHANISMS IN HUMAN NEUTROPHILS (PMNS) FOR AGGREGATION, SUPEROXIDE ANION (O2) GENERATION AND DEGRANULATION
Kolasinski, SL; Haines, KA; Weissmann, G
1990 Apr;38(2):A369-A369, Clinical research
— id: 31963, year: 1990, vol: 38, page: A369, stat: Journal Article,

LOCALIZATION OF LOW-MOLECULAR-WEIGHT GTP BINDING-PROTEINS IN MEMBRANES OF HUMAN NEUTROPHIL GRANULES
Philips, MR; Rosenfeld, MG; Abramson, SB; Kolasinski, SL; Haines, KA; Weissmann, G
1990 Apr;38(2):A351-A351, Clinical research
— id: 32065, year: 1990, vol: 38, page: A351, stat: Journal Article,

ARACHIDONATE (20-4) AND DOCOSAHEXANOATE (22-6) AS DIRECT MESSENGERS OF INFLAMMATION - EFFECT ON G-PROTEINS IN MARINE SPONGE AGGREGATION
Weissmann, G; Sands, PJ; Haines, KA; Abramson, SB; Leszczynska, JM
1990 Apr;38(2):A596-A596, Clinical research
— id: 31977, year: 1990, vol: 38, page: A596, stat: Journal Article,

NEUTROPHIL ACTIVATION - PROTEIN-I OF N-GONORRHEA DEMONSTRATES A PHOSPHATIDYLCHOLINE-SPECIFIC PHOSPHOLIPASE-C IN NEUTROPHILS
Haines, KA; Reibman, J; Abramson, SB; Blake, M; Weissmann, G
1989 Apr;37(2):A564-A564, Clinical research
— id: 31713, year: 1989, vol: 37, page: A564, stat: Journal Article,

MICROTUBULE-DEPENDENT AND INDEPENDENT PATHWAYS OF NEUTROPHIL ACTIVATION
Reibman, J; Haines, KA; Weissman, G
1989 Apr;37(2):A481-A481, Clinical research
— id: 31704, year: 1989, vol: 37, page: A481, stat: Journal Article,

NONSTEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS) INHIBIT NEUTROPHIL (PMN) FUNCTIONS VIA EFFECTS AT THE G-PROTEIN OF THE PLASMA- MEMBRANE
Abramson, S; Haines, K; Leszczynska, J; Reibman, J; Weissmann, G
1988 Apr;36(3):A548-A548, Clinical research
— id: 31506, year: 1988, vol: 36, page: A548, stat: Journal Article,

Neutrophil activation: evidence for two sources of diacylglycerol distinguished by protein I of Neisseria gonorrhoeae
Haines KA; Reibman J; Vosshall L; Weissmann G
1988 ;101:163-172, Transactions of the Association of American Physicians
— id: 11279, year: 1988, vol: 101, page: 163, stat: Journal Article,

Protein I, a translocatable ion channel from Neisseria gonorrhoeae, selectively inhibits exocytosis from human neutrophils without inhibiting O2- generation
Haines KA; Yeh L; Blake MS; Cristello P; Korchak H; Weissmann G
1988 Jan 15;263(2):945-951, Journal of biological chemistry
— id: 11206, year: 1988, vol: 263, page: 945, stat: Journal Article,

NEUTROPHIL ACTIVATION - EVIDENCE FOR 2 SOURCES OF DIACYLGLYCEROL DISTINGUISHED BY PROTEIN-I OF N - GONORRHOEAE
Haines, KA; Reibman, J; Vosshall, L; Weissmann, G
1988 Apr;36(3):A620-A620, Clinical research
— id: 31518, year: 1988, vol: 36, page: A620, stat: Journal Article,

Activation of the human neutrophil by calcium-mobilizing ligands. II. Correlation of calcium, diacyl glycerol, and phosphatidic acid generation with superoxide anion generation
Korchak HM; Vosshall LB; Haines KA; Wilkenfeld C; Lundquist KF; Weissmann G
1988 Aug 15;263(23):11098-11105, Journal of biological chemistry
— id: 59681, year: 1988, vol: 263, page: 11098, stat: Journal Article,

Changes in diacylglycerol labeling, cell shape, and protein phosphorylation distinguish "triggering" from "activation" of human neutrophils
Reibman J; Korchak HM; Vosshall LB; Haines KA; Rich AM; Weissmann G
1988 May 5;263(13):6322-6328, Journal of biological chemistry
— id: 11095, year: 1988, vol: 263, page: 6322, stat: Journal Article,

COCAINE DERIVATIVES BLUNT NEUTROPHIL RESPONSES
Callegari, P; Abramson, S; Philips, M; Haines, K; Reibman, J; Weissmann, G
1987 Apr;35(3):A613-A613, Clinical research
— id: 31199, year: 1987, vol: 35, page: A613, stat: Journal Article,

The leukotriene B4 paradox: neutrophils can, but will not, respond to ligand-receptor interactions by forming leukotriene B4 or its omega-metabolites
Haines KA; Giedd KN; Rich AM; Korchak HM; Weissmann G
1987 Jan 1;241(1):55-62, Biochemical journal
— id: 59689, year: 1987, vol: 241, page: 55, stat: Journal Article,

Leukotriene B4 paradox: neutrophils can, but will not, respond to ligand-receptor interactions by forming leukotriene B4 or its omega-metabolites
Haines KA; Giedd KN; Rich AM; Reibman J; Korchak HM; Weissmann G
1987 ;17B:890-899, Advances in prostaglandin thromboxane & leukotriene research
— id: 11433, year: 1987, vol: 17B, page: 890, stat: Journal Article,

PROTEIN-I OF THE GONOCOCCUS SELECTIVELY INHIBITS NEUTROPHIL FUNCTIONS
Haines, KA; Blake, M; Korchak, HM; Weissmann, G
1987 Mar 1;46(3):445-445, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 31261, year: 1987, vol: 46, page: 445, stat: Journal Article,

PROTEIN-I OF NEISSERIA-GONORRHOEAE INHIBITS SHAPE CHANGES AND AGGREGATION CAUSED BY THE CHEMOATTRACTANT F-MET-LEU-PHE
Haines, KA; Rich, AM; Korchak, HM; Weissmann, G
1987 Apr;35(3):A476-A476, Clinical research
— id: 31192, year: 1987, vol: 35, page: A476, stat: Journal Article,

NEUTROPHIL ACTIVATION - CHEMOATTRACTANTS DIFFER IN THEIR CAPACITY TO ELICIT PROTEIN-PHOSPHORYLATION
Reibman, J; Haines, KA; Korchak, HM; Weissmann, G
1987 Mar 1;46(3):987-987, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 31268, year: 1987, vol: 46, page: 987, stat: Journal Article,

PHOSPHORYLATION OF THE 47KDA TARGET PROTEIN IS NOT SUFFICIENT FOR SUPEROXIDE ANION PRODUCTION IN NEUTROPHILS
Reibman, J; Korchak, HM; Haines, KA; Vosshall, LB; Weissmann, G
1987 Apr;35(3):A537-A537, Clinical research
— id: 31195, year: 1987, vol: 35, page: A537, stat: Journal Article,

Non-steroidal anti-inflammatory drugs: how do they work?
Weissmann G; Korchak H; Ludewig R; Edelson H; Haines K; Levin RI; Herman R; Rider L; Kimmel S; Abramson S
1987 ;8(1):6-17, European journal of rheumatology & inflammation
— id: 59687, year: 1987, vol: 8, page: 6, stat: Journal Article,

Leukotriene B4 synthesis and metabolism by neutrophils and granule-free cytoplasts
Haines KA; Giedd KN; Weissmann G
1986 Jan 15;233(2):583-588, Biochemical journal
— id: 59696, year: 1986, vol: 233, page: 583, stat: Journal Article,

THE LTB4 PARADOX - NEUTROPHILS CAN BUT WILL NOT MAKE LTB4 IN RESPONSE TO INFLAMMATORY STIMULI
HAINES, KA; GIEDD, KN; WEISSMANN, G
1986 APR ;34(2):A625-A625, Clinical research
— id: 41406, year: 1986, vol: 34, page: A625, stat: Journal Article,

PROTEIN-I OF THE GONOCOCCUS INHIBITS DISCRETE NEUTROPHIL FUNCTIONS
HAINES, KA; RICH, AM; BLAKE, M; KORCHAK, HM
1986 APR ;34(2):A519-A519, Clinical research
— id: 41401, year: 1986, vol: 34, page: A519, stat: Journal Article,

CYTOPLASMIC PH FALLS IN ACTIVATED NEUTROPHILS - CORRELATION WITH CELL FUNCTIONS
KORCHAK, HM; VIENNE, K; ROBERTS, CS; WILKENFELD, C; HAINES, KA; WEISSMANN, G
1986 MAR 5 ;45(4):852-852, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 41494, year: 1986, vol: 45, page: 852, stat: Journal Article,

SUPEROXIDE ANION GENERATION IN LTB4 ACTIVATED NEUTROPHILS - INADEQUACY OF CYTOSOLIC CALCIUM AND DIACYL GLYCEROL AS SIGNALS
KORCHAK, HM; VOSSHALL, LB; REIBMAN, J; RICH, AM; HAINES, KA
1986 NOV ;103(5):A504-A504, Journal of cell biology
— id: 41326, year: 1986, vol: 103, page: A504, stat: Journal Article,

Colchicine inhibits ionophore-induced formation of leukotriene B4 by human neutrophils: the role of microtubules
Reibman J; Haines KA; Rich AM; Cristello P; Giedd KN; Weissmann G
1986 Feb 1;136(3):1027-1032, Journal of immunology (1950)
— id: 59695, year: 1986, vol: 136, page: 1027, stat: Journal Article,

Modes of action of aspirin-like drugs
Abramson S; Korchak H; Ludewig R; Edelson H; Haines K; Levin RI; Herman R; Rider L; Kimmel S; Weissmann G
1985 Nov;82(21):7227-7231, Proceedings of the National Academy of Sciences of the United States of America
— id: 59701, year: 1985, vol: 82, page: 7227, stat: Journal Article,

LUPUS CRISIS - C3A DESARG AND LIPOXYGENASE PRODUCTS APPEAR IN PLASMA
Abramson, S; Belmont, HM; Ludewig, R; Kimmel, S; Haines, K; Weissmann, G
1985 ;33(2):A503-A503, Clinical research
— id: 30925, year: 1985, vol: 33, page: A503, stat: Journal Article,

Circulating hydroxy fatty acids in familial Mediterranean fever
Aisen PS; Haines KA; Given W; Abramson SB; Pras M; Serhan C; Hamberg M; Samuelsson B; Weissmann G
1985 Feb;82(4):1232-1236, Proceedings of the National Academy of Sciences of the United States of America
— id: 9772, year: 1985, vol: 82, page: 1232, stat: Journal Article,

COLCHICINE INHIBITION OF LEUKOTRIENE-B4 PRODUCTION BY HUMAN- NEUTROPHILS REQUIRES INTACT MICROTUBULES
Reibman, J; Haines, KA; Rich, AM; Giedd, KN; Cristello, P; Weissmann, G
1985 ;33(2):A511-A511, Clinical research
— id: 30926, year: 1985, vol: 33, page: A511, stat: Journal Article,

BIOLOGICALLY-ACTIVE LIPOXYGENASE PRODUCTS IN THE SERA OF PATIENTS WITH FAMILIAL MEDITERRANEAN FEVER (FMF)
AISEN, P; HAINES, K; GIVEN, W; ABRAMSON, S; PRAS, M; WEISSMANN, G
1984 ;32(2):A363-A363, Clinical research
— id: 40975, year: 1984, vol: 32, page: A363, stat: Journal Article,

The relation of Langerhans cells to other dendritic cells and macrophages
Flotte, T.J.; Haines, K.; Miller, K.; Springer, T.; Gigli, I.; Thorbecke, G.J
Mononuclear Phagocyte Biology New York : Marcel Dekker, 1984,
— id: 2508, year: 1984, vol: , page: 51, stat: Chapter,

LEUKOTRIENE-B4 PRODUCTION BY NEUTROPHILS IS INDEPENDENT OF DE-GRANULATION
HAINES, KA; GIEDD, K; KORCHAK, HM; WEISSMANN, G
1984 ;32(2):A471-A471, Clinical research
— id: 40977, year: 1984, vol: 32, page: A471, stat: Journal Article,

Calcium dependent aggregation of marine sponge cells is provoked by leukotriene B4 and inhibited by inhibitors of arachidonic acid oxidation
Rich AM; Weissmann G; Anderson C; Vosshall L; Haines KA; Humphreys T; Dunham P
1984 Jun 29;121(3):863-870, Biochemical & biophysical research communications
— id: 59710, year: 1984, vol: 121, page: 863, stat: Journal Article,

STIMULUS-SECRETION COUPLING IN THE MARINE SPONGE
RICH, AM; CRISTELLO, P; HAINES, KA; WEISSMANN, G
1984 ;99(4):A221-A221, Journal of cell biology
— id: 40892, year: 1984, vol: 99, page: A221, stat: Journal Article,

STIMULUS-SECRETION COUPLING IN THE MARINE SPONGE - RELEASE OF ADHESIVE MATERIAL
RICH, AM; CRISTELLO, P; HAINES, KA; WEISSMANN, G
1984 ;43(3):706-706, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 41014, year: 1984, vol: 43, page: 706, stat: Journal Article,

The cellular effects of nonsteroidal anti-inflammatory drugs cannot be due to inhibition of prostaglandin release
Weissmann G; Rich AM; Anderson C; Haines KA; Korchak HM; Dunham P
1984 ;97:369-383, Transactions of the Association of American Physicians
— id: 59722, year: 1984, vol: 97, page: 369, stat: Journal Article,

Staining of Langerhans cells with monoclonal antibodies to macrophages and lymphoid cells
Haines KA; Flotte TJ; Springer TA; Gigli I; Thorbecke GJ
1983 Jun;80(11):3448-3451, Proceedings of the National Academy of Sciences of the United States of America
— id: 8844, year: 1983, vol: 80, page: 3448, stat: Journal Article,

THE ROLE OF CALCIUM IN NEUTROPHIL ACTIVATION - MOBILIZATION OF MULTIPLE CALCIUM POOLS
KORCHAK, HM; VIENNE, K; WILKENFELD, C; ROBERTS, CS; RUTHERFORD, LE; HAINES, KA; WEISSMANN, G
1983 ;97(5):A160-A160, Journal of cell biology
— id: 40608, year: 1983, vol: 97, page: A160, stat: Journal Article,