Gilbert J Grant

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Gilbert Grant

Associate Professor, Department of Anesthesiology, Perioperative Care, and Pain Medicine
Director of Obstetric Anesthesiology
Vice Chair Academic Affairs
NYU Anesthesia Associates

Contact Info

Address
560 First Avenue
New York, NY 10016

212/263-5548

Education

1983-1986 — NYU Medical Center (Anesthesiology), Residency Training

Research Summary

Pain after surgery and trauma is often inadequately treated, resulting in unecessary suffering and possibly leading to significant medical complications. A simple, effective, and reliable means of providing analgesia would be greatly beneficial. To this end, our laboratory has focused on using liposomes, currently used as a biocompatable means of drug delivery for various pharmaceuticals, as slow-release, drug-delivery vehicles. By acting as a slow-release vehicle for analgesics, liposomes potentially can provide prolonged analgesia in patients suffering from pain with a single drug administration. Our laboratory is involved in developing liposomal delivery systems for local anesthetics and narcotics. To date, we have demonstrated that liposomal encapsulation produces a five to ten times prolongation of analgesia when compared to free drug in animal models. We plan to assess the safety of these formulations so that they can then undergo efficacy testing in humans. We view these promising results as offering hope that liposomal narcotic and local anesthetic formulations may be used clinically to significantly decrease pain and suffering in patients.

Research Interests

Prolonged Analgesia Using Liposomal Delivery Systems

Marketing or strategy? Defining the best approach to expand the anesthesiology workforce in Israel
Lewis, Michael C; Grant, Gilbert J. Marketing or strategy? Defining the best approach to expand the anesthesiology workforce in Israel. Israel journal of health policy research. 2015 Aug 25;4:44-44 (1742132)

Transnasal topical sphenopalatine ganglion block to treat tension headache in a pregnant patient
Grant, G J; Schechter, D; Redai, I; Lax, J. Transnasal topical sphenopalatine ganglion block to treat tension headache in a pregnant patient [Letter]. International journal of obstetric anesthesia. 2014 May 10;23(3):292-293 (1153432)

Epidural Simulation to Train Residents Prior to Obstetric Anesthesia Rotation
Lax, Jerome; Szyld, Demian; Ng, Grace; Riles, Thomas; Grant, Gilbert. Epidural Simulation to Train Residents Prior to Obstetric Anesthesia Rotation [Meeting Abstract]. Simulation in healthcare. 2013 Dec;8(6):?-? (1622002)

Prolonged analgesia from Bupisome and Bupigel formulations: From design and fabrication to improved stability
Cohen, Rivka; Kanaan, Hiba; Grant, Gilbert J; Barenholz, Yechezkel. Prolonged analgesia from Bupisome and Bupigel formulations: From design and fabrication to improved stability. Journal of controlled release. 2011 Dec 30;160(2):346-352 (169587)

Safely giving regional anesthesia to gravidas with clotting disorders
Grant GJ. Safely giving regional anesthesia to gravidas with clotting disorders. Contemporary ob/gyn. 2007 ;52(8):40-2,45,49 Aug (74275)