Els D.T. Fieremans

Biosketch / Results /

Els Fieremans

Assistant Professor, Department of Radiology

Contact Info

Address
660 First Avenue
New York, NY 10016

212/263-3344
Els.Fieremans@nyumc.org


Research Summary

I have been working on diffusion MRI since 2003. During my Ph.D., I introduced anisotropic diffusion fiber phantoms useful for testing diffusion MRI sequences and fiber tractography. I also developed numerical Monte Carlo simulations of random walkers to model the diffusion signal in brain tissue.

In my current research, I continue to focus on validation methods for diffusion MRI including both hardware and numerical phantoms, as well as animal models. I thereby seek to develop and translate new imaging markers for neurodegeneration, as well as body diffusion applications in muscle and prostate, using advanced biophysical modeling of non-Gaussian and time-dependent diffusion in biological tissue.

Research Keywords

Magnetic Resonance Imaging; Biophysics; Diffusion MRI

Diffusion-weighted imaging uncovers likely sources of processing-speed deficits in schizophrenia
Kochunov, Peter; Rowland, Laura M; Fieremans, Els; Veraart, Jelle; Jahanshad, Neda; Eskandar, George; Du, Xiaoming; Muellerklein, Florian; Savransky, Anya; Shukla, Dinesh; Sampath, Hemalatha; Thompson, Paul M; Hong, L Elliot. Diffusion-weighted imaging uncovers likely sources of processing-speed deficits in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2016 Nov 22;113(47):13504-13509 (2304572)

Denoising of diffusion MRI using random matrix theory
Veraart, Jelle; Novikov, Dmitry S; Christiaens, Daan; Ades-Aron, Benjamin; Sijbers, Jan; Fieremans, Els. Denoising of diffusion MRI using random matrix theory. Neuroimage. 2016 Nov 15;142:394-406 (2219232)

Palliative CT-Guided Cordotomy for Medically Intractable Pain in Patients with Cancer
Shepherd, T M; Hoch, M J; Cohen, B A; Bruno, M T; Fieremans, E; Rosen, G; Pacione, D; Mogilner, A Y. Palliative CT-Guided Cordotomy for Medically Intractable Pain in Patients with Cancer. AJNR. American journal of neuroradiology. 2016 Nov 3;:?-? (2296992)

Diffusion MRI noise mapping using random matrix theory
Veraart, Jelle; Fieremans, Els; Novikov, Dmitry S. Diffusion MRI noise mapping using random matrix theory. Magnetic resonance in medicine. 2016 Nov;76(5):1582-1593 (1856842)

In vivo measurement of membrane permeability and myofiber size in human muscle using time-dependent diffusion tensor imaging and the random permeable barrier model
Fieremans, Els; Lemberskiy, Gregory; Veraart, Jelle; Sigmund, Eric E; Gyftopoulos, Soterios; Novikov, Dmitry S. In vivo measurement of membrane permeability and myofiber size in human muscle using time-dependent diffusion tensor imaging and the random permeable barrier model. NMR in biomedicine. 2016 Oct 7;:?-? (2274332)