Francisco J Esteva

Biosketch / Results /

Francisco J Esteva, M.D.

Professor; Dir Breast Medical Oncology Program; Assoc Dir of Clin Investigate Perlmutter CancerCtr; Co Dir of the Breast Cancer DMG; Co Dir Phase 1 Drug Dev Pgm Div Hematology Med Onc
Department of Medicine (Hematology Div)

Clinical Addresses

Clinical Cancer Center
NYU Langone Medical Center
160 E. 34th Street
New York, NY 10016
Handicap Access: yes
Phone: 212-731-5657
Fax: 212-731-5342

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Medical Specialties

Medical Oncology

Insurance

AETNA HMO, AETNA INDEMNITY, AETNA MEDICARE, AETNA POS, AETNA PPO/EPO, AFFINITY, CIGNA EPO/POS, Cigna PPO, ELDERPLAN, FIDELIS CHLD HLTH, FIDELIS EXCHANGE, FIDELIS FAM HLTH, FIDELIS MEDICARE, Fidelis Medicaid, GHI CBP, HEALTHPLUS CHLD HLTH (AMERIGROUP), HEALTHPLUS FAM HLTH (AMERIGROUP), HEALTHPLUS MEDICAID (AMERIGROUP), HEALTHREPUBLIC, HIP ACCESS I, HIP ACCESS II, HIP CHLD HLTH, HIP EPO/PPO, HIP HMO, HIP MEDICARE, HIP POS, LOCAL 1199 PPO, MAGNACARE PPO, METROPLUS CHLD HLTH, METROPLUS FAM HLTH, MULTIPLAN/PHCS PPO, Medicare, MetroPlus Medicaid, NYS EMPIRE PLAN, OSCAR, OXFORD EXCHANGE, OXFORD FREEDOM, Oxford Liberty, Oxford Medicare, Tricare, UHC COMMUNITY & STATE PLAN, UHC EPO, UHC HMO, UHC MEDICARE, UHC POS, UHC PPO, UHC TOP TIER, UNITED EXCHANGE- COMPASS, WELLCARE CHLD HLTH, WELLCARE FAM HLTH WELLCARE MEDICAID, WELLCARE MEDICARE

Insurance Disclaimer: Insurance listed above may not be accepted at all office locations. Please confirm prior to each visit. The information presented here may not be complete or may have changed.

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Board Certification

2007 — Ab Internal Medicine (Medical Oncology)

Education

1982-1988 — Universidad de Zaragoza, Medical Education
1991-1992 — Cooper Hospital-Univ. Med. Center (Internal Medicine), Internship
1992-1994 — Cooper Hospital-Univ. Med. Center (Internal Medicine), Residency Training
1994-1996 — Georgetown University Hospital (Medical Oncology), Clinical Fellowships

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Research Interests

Dr. Esteva is interested in the clinical developoment of targeted therapies and biomarkers in breast cancer.

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Leptomeningeal disease and breast cancer: the importance of tumor subtype
Abouharb, Sausan; Ensor, Joe; Loghin, Monica Elena; Katz, Ruth; Moulder, Stacy L; Esteva, Francisco J; Smith, Benjamin; Valero, Vicente; Hortobagyi, Gabriel N; Melhem-Bertrandt, Amal
2014 Jul;:102-114, Breast cancer research & treatment
— id: 1075552, year: 2014, vol: , page: 102, stat: Journal Article,

Genome-Based Risk Prediction for Early Stage Breast Cancer
Adaniel, Christina; Jhaveri, Komal; Heguy, Adriana; Esteva, Francisco J
2014 Sep;:4757-4757, Oncologist
— id: 1180912, year: 2014, vol: , page: 4757, stat: Journal Article,

HER family kinase domain mutations promote tumor progression and can predict response to treatment in human breast cancer
Boulbes, Delphine R; Arold, Stefan T; Chauhan, Gaurav B; Blachno, Korina V; Deng, Nanfu; Chang, Wei-Chao; Jin, Quanri; Huang, Tzu-Hsuan; Hsu, Jung-Mao; Brady, Samuel W; Bartholomeusz, Chandra; Ladbury, John E; Stone, Steve; Yu, Dihua; Hung, Mien-Chie; Esteva, Francisco J
2014 Nov;:201-223, Molecular oncology
— id: 1369882, year: 2014, vol: , page: 201, stat: Journal Article,

Effects of obesity on transcriptomic changes and cancer hallmarks in estrogen receptor-positive breast cancer
Fuentes-Mattei, Enrique; Velazquez-Torres, Guermarie; Phan, Liem; Zhang, Fanmao; Chou, Ping-Chieh; Shin, Ji-Hyun; Choi, Hyun Ho; Chen, Jiun-Sheng; Zhao, Ruiying; Chen, Jian; Gully, Chris; Carlock, Colin; Qi, Yuan; Zhang, Ya; Wu, Yun; Esteva, Francisco J; Luo, Yongde; McKeehan, Wallace L; Ensor, Joe; Hortobagyi, Gabriel N; Pusztai, Lajos; Fraser Symmans, W; Lee, Mong-Hong; Jim Yeung, Sai-Ching
2014 Jul;106(7):?-? e99993, Journal of the National Cancer Institute
— id: 1050952, year: 2014, vol: 106, page: ?, stat: Journal Article,

Systemic Therapy for Patients With Advanced Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline
Giordano, Sharon H; Temin, Sarah; Kirshner, Jeffrey J; Chandarlapaty, Sarat; Crews, Jennie R; Davidson, Nancy E; Esteva, Francisco J; Gonzalez-Angulo, Ana M; Krop, Ian; Levinson, Jennifer; Lin, Nancy U; Modi, Shanu; Patt, Debra A; Perez, Edith A; Perlmutter, Jane; Ramakrishna, Naren; Winer, Eric P
2014 May;:591-598, Journal of clinical oncology
— id: 979372, year: 2014, vol: , page: 591, stat: Journal Article,

Pertuzumab in the Treatment of HER2+ Breast Cancer
Jhaveri, Komal; Esteva, Francisco J
2014 Apr;12(4):591-598, Journal of the National Comprehensive Cancer Network : JNCCN
— id: 979362, year: 2014, vol: 12, page: 591, stat: Journal Article,

Circulating proteolytic products of carboxypeptidase N for early detection of breast cancer
Li, Yaojun; Li, Yueguo; Chen, Tao; Kuklina, Anna S; Bernard, Paul; Esteva, Francisco J; Shen, Haifa; Ferrari, Mauro; Hu, Ye
2014 Jan;60(1):233-242, Clinical chemistry
— id: 979332, year: 2014, vol: 60, page: 233, stat: Journal Article,

Effect of adjuvant/neoadjuvant trastuzumab on clinical outcomes in patients with HER2-positive metastatic breast cancer
Murthy, Rashmi K; Varma, Ankur; Mishra, Priyankana; Hess, Kenneth R; Young, Elliana; Murray, James L; Koenig, Kimberly H; Moulder, Stacy L; Melhem-Bertrandt, Amal; Giordano, Sharon H; Booser, Daniel; Valero, Vicente; Hortobagyi, Gabriel N; Esteva, Francisco J
2014 Mar;:542-559, Cancer
— id: 979352, year: 2014, vol: , page: 542, stat: Journal Article,

Gene signature guided Dasatinib therapy in metastatic breast cancer
Pusztai, Lajos; Moulder, Stacy; Altan, Mehmet; Kwiatkowski, Danielle; Valero, Vicente; Ueno, Naoto T; Esteva, Francisco J; Avritscher, Rony; Qi, Yuan; Strauss, Lewis C; Hortobagyi, Gabriel N; Hatzis, Christos; Symmans, W Fraser
2014 Aug;:1133-1138, Clinical cancer research
— id: 1162812, year: 2014, vol: , page: 1133, stat: Journal Article,

Gene Signature-Guided Dasatinib Therapy in Metastatic Breast Cancer
Pusztai, Lajos; Moulder, Stacy; Altan, Mehmet; Kwiatkowski, Danielle; Valero, Vicente; Ueno, Naoto T; Esteva, Francisco J; Avritscher, Rony; Qi, Yuan; Strauss, Lewis; Hortobagyi, Gabriel N; Hatzis, Christos; Symmans, WFraser
2014 OCT 15;20(20):5265-5271, Clinical cancer research
— id: 1358062, year: 2014, vol: 20, page: 5265, stat: Journal Article,

Recommendations on Disease Management for Patients With Advanced Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases: American Society of Clinical Oncology Clinical Practice Guideline
Ramakrishna, Naren; Temin, Sarah; Chandarlapaty, Sarat; Crews, Jennie R; Davidson, Nancy E; Esteva, Francisco J; Giordano, Sharon H; Gonzalez-Angulo, Ana M; Kirshner, Jeffrey J; Krop, Ian; Levinson, Jennifer; Modi, Shanu; Patt, Debra A; Perez, Edith A; Perlmutter, Jane; Winer, Eric P; Lin, Nancy U
2014 May;:591-598, Journal of clinical oncology
— id: 979382, year: 2014, vol: , page: 591, stat: Journal Article,

Biomarker-guided sequential targeted therapies to overcome therapy resistance in rapidly evolving highly aggressive mammary tumors
Sahin, Ozgur; Wang, Qingfei; Brady, Samuel W; Ellis, Kenneth; Wang, Hai; Chang, Chia-Chi; Zhang, Qingling; Priya, Preety; Zhu, Rui; Wong, Stephen T; Landis, Melissa D; Muller, William J; Esteva, Francisco J; Chang, Jenny; Yu, Dihua
2014 May;24(5):542-559, Cell research
— id: 979342, year: 2014, vol: 24, page: 542, stat: Journal Article,

Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes
Su, Xiaoping; Malouf, Gabriel G; Chen, Yunxin; Zhang, Jianping; Yao, Hui; Valero, Vicente; Weinstein, John N; Spano, Jean-Philippe; Meric-Bernstam, Funda; Khayat, David; Esteva, Francisco J
2014 Sep;:9864-9876 e109272, Oncotarget
— id: 1300012, year: 2014, vol: , page: 9864, stat: Journal Article,

Incidence, risk factors, and management of infusion-related reactions in breast cancer patients receiving trastuzumab
Thompson, Lisa M; Eckmann, Karen; Boster, Bonnie L; Hess, Kenneth R; Michaud, Laura B; Esteva, Francisco J; Hortobagyi, Gabriel N; Barnett, Chad M
2014 ;19(3):228-234, Oncologist
— id: 851852, year: 2014, vol: 19, page: 228, stat: Journal Article,

Incidence, risk factors, andmanagement of infusion-related reactions in breast cancer patients receiving trastuzumab
Thompson, LM; Eckmann, K; Boster, BL; Hess, KR; Michaud, LB; Esteva, FJ; Hortobagyi, GN; Barnett, CM
2014 ;19(3):228-234, Oncologist
— id: 1022192, year: 2014, vol: 19, page: 228, stat: Journal Article,

Elevated serum P1NP predicts development of bone metastasis and survival in early-stage breast cancer
Dean-Colomb, Windy; Hess, Kenneth R; Young, Elliana; Gornet, Terrie G; Handy, Beverly C; Moulder, Stacy L; Ibrahim, Nuhad; Pusztai, Lajos; Booser, Daniel; Valero, Vicente; Hortobagyi, Gabriel N; Esteva, Francisco J
2013 Jan;137(2):631-636, Breast cancer research & treatment
— id: 517192, year: 2013, vol: 137, page: 631, stat: Journal Article,

An open-label safety study of lapatinib plus trastuzumab plus paclitaxel in first-line HER2-positive metastatic breast cancer
Esteva, Francisco J; Franco, Sandra X; Hagan, Maura K; Brewster, Abenaa M; Somer, Robert A; Williams, Will; Florance, Allison M; Turner, Simon; Stein, Steven; Perez, Alejandra
2013 Jun;18(6):661-666, Oncologist
— id: 517182, year: 2013, vol: 18, page: 661, stat: Journal Article,

Phase I trial of exemestane in combination with metformin and rosiglitazone in nondiabetic obese postmenopausal women with hormone receptor-positive metastatic breast cancer
Esteva, Francisco J; Moulder, Stacy L; Gonzalez-Angulo, Ana M; Ensor, Joe; Murray, James L; Green, Marjorie C; Koenig, Kimberly B; Lee, Mong-Hong; Hortobagyi, Gabriel N; Yeung, Sai-Ching
2013 Jan;71(1):63-72, Cancer chemotherapy & pharmacology
— id: 517212, year: 2013, vol: 71, page: 63, stat: Journal Article,

Planning cancer control in Latin America and the Caribbean
Goss, Paul E; Lee, Brittany L; Badovinac-Crnjevic, Tanja; Strasser-Weippl, Kathrin; Chavarri-Guerra, Yanin; Louis, Jessica St; Villarreal-Garza, Cynthia; Unger-Saldana, Karla; Ferreyra, Mayra; Debiasi, Marcio; Liedke, Pedro Er; Touya, Diego; Werutsky, Gustavo; Higgins, Michaela; Fan, Lei; Vasconcelos, Claudia; Cazap, Eduardo; Vallejos, Carlos; Mohar, Alejandro; Knaul, Felicia; Arreola, Hector; Batura, Rekha; Luciani, Silvana; Sullivan, Richard; Finkelstein, Dianne; Simon, Sergio; Barrios, Carlos; Kightlinger, Rebecca; Gelrud, Andres; Bychkovsky, Vladimir; Lopes, Gilberto; Stefani, Stephen; Blaya, Marcelo; Souza, Fabiano Hahn; Santos, Franklin Santana; Kaemmerer, Alberto; de Azambuja, Evandro; Zorilla, Andres Felipe Cardona; Murillo, Raul; Jeronimo, Jose; Tsu, Vivien; Carvalho, Andre; Gil, Carlos Ferreira; Sternberg, Cinthya; Duenas-Gonzalez, Alfonso; Sgroi, Dennis; Cuello, Mauricio; Fresco, Rodrigo; Reis, Rui Manuel; Masera, Guiseppe; Gabus, Raul; Ribeiro, Raul; Knust, Renata; Ismael, Gustavo; Rosenblatt, Eduardo; Roth, Berta; Villa, Luisa; Solares, Argelia Lara; Leon, Marta Ximena; Torres-Vigil, Isabel; Covarrubias-Gomez, Alfredo; Hernandez, Andres; Bertolino, Mariela; Schwartsmann, Gilberto; Santillana, Sergio; Esteva, Francisco; Fein, Luis; Mano, Max; Gomez, Henry; Hurlbert, Marc; Durstine, Alessandra; Azenha, Gustavo
2013 Apr;14(5):391-436, Lancet oncology
— id: 370442, year: 2013, vol: 14, page: 391, stat: Journal Article,

Speech prosthesis aspiration
Grosu, Horiana B; Esteva, Francisco J; Jimenez, Carlos A; Morice, Rodolfo C
2013 Jan;30(1):85-85, Emergency medicine journal
— id: 517222, year: 2013, vol: 30, page: 85, stat: Journal Article,

Effect of HER2 status on distant recurrence in early stage breast cancer
Hess, Kenneth R; Esteva, Francisco J
2013 Jan;137(2):449-455, Breast cancer research & treatment
— id: 517202, year: 2013, vol: 137, page: 449, stat: Journal Article,

Human endogenous retrovirus type K antibodies and mRNA as serum biomarkers of early-stage breast cancer
Wang-Johanning, Feng; Li, Ming; Esteva, Francisco J; Hess, Kenneth R; Yin, Bingnan; Rycaj, Kiera; Plummer, Joshua B; Garza, Jeremy G; Ambs, Stefan; Johanning, Gary L
2013 Jul;:587-595, International journal of cancer
— id: 517172, year: 2013, vol: , page: 587, stat: Journal Article,

Short-term biomarker modulation prevention study of anastrozole in women at increased risk for second primary breast cancer
Arun, Banu; Valero, Vicente; Liu, Diane; Brewster, Abenaa; Green, Marjorie; Gutierrez-Barrera, Angelica; Akar, Ugur; Rivera, Edgardo; Esteva, Francisco J; Buzdar, Aman U; Hortobagyi, Gabriel N; Sneige, Nour
2012 Feb;5(2):276-282, Cancer prevention research (Philadelphia, Pa.)
— id: 517302, year: 2012, vol: 5, page: 276, stat: Journal Article,

MEK1/2 inhibitor selumetinib (AZD6244) inhibits growth of ovarian clear cell carcinoma in a PEA-15-dependent manner in a mouse xenograft model
Bartholomeusz, Chandra; Oishi, Tetsuro; Saso, Hitomi; Akar, Ugur; Liu, Ping; Kondo, Kimie; Kazansky, Anna; Krishnamurthy, Savitri; Lee, Jangsoon; Esteva, Francisco J; Kigawa, Junzo; Ueno, Naoto T
2012 Feb;11(2):360-369, Molecular cancer therapeutics
— id: 517312, year: 2012, vol: 11, page: 360, stat: Journal Article,

TBCRC 001: randomized phase II study of cetuximab in combination with carboplatin in stage IV triple-negative breast cancer
Carey, Lisa A; Rugo, Hope S; Marcom, P Kelly; Mayer, Erica L; Esteva, Francisco J; Ma, Cynthia X; Liu, Minetta C; Storniolo, Anna Maria; Rimawi, Mothaffar F; Forero-Torres, Andres; Wolff, Antonio C; Hobday, Timothy J; Ivanova, Anastasia; Chiu, Wing-Keung; Ferraro, Madlyn; Burrows, Emily; Bernard, Philip S; Hoadley, Katherine A; Perou, Charles M; Winer, Eric P
2012 Jul;30(21):2615-2623, Journal of clinical oncology
— id: 517252, year: 2012, vol: 30, page: 2615, stat: Journal Article,

Epithelial-mesenchymal transition and stem cell markers in patients with HER2-positive metastatic breast cancer
Giordano, Antonio; Gao, Hui; Anfossi, Simone; Cohen, Evan; Mego, Michal; Lee, Bang-Ning; Tin, Sanda; De Laurentiis, Michele; Parker, Charla A; Alvarez, Ricardo H; Valero, Vicente; Ueno, Naoto T; De Placido, Sabino; Mani, Sendurai A; Esteva, Francisco J; Cristofanilli, Massimo; Reuben, James M
2012 Nov;11(11):2526-2534, Molecular cancer therapeutics
— id: 517242, year: 2012, vol: 11, page: 2526, stat: Journal Article,

Estrogen receptor (ER) mRNA and ER-related gene expression in breast cancers that are 1% to 10% ER-positive by immunohistochemistry
Iwamoto, Takayuki; Booser, Daniel; Valero, Vicente; Murray, James L; Koenig, Kimberly; Esteva, Francisco J; Ueno, Naoto T; Zhang, Jie; Shi, Weiwei; Qi, Yuan; Matsuoka, Junji; Yang, Elliana J; Hortobagyi, Gabriel N; Hatzis, Christos; Symmans, W Fraser; Pusztai, Lajos
2012 Mar;30(7):729-734, Journal of clinical oncology
— id: 517292, year: 2012, vol: 30, page: 729, stat: Journal Article,

Plasma microRNA 210 levels correlate with sensitivity to trastuzumab and tumor presence in breast cancer patients
Jung, Eun-Jung; Santarpia, Libero; Kim, Juyeon; Esteva, Francisco J; Moretti, Erica; Buzdar, Aman U; Di Leo, Angelo; Le, Xiao-Feng; Bast, Robert C Jr; Park, Soon-Tae; Pusztai, Lajos; Calin, George A
2012 May;118(10):2603-2614, Cancer
— id: 517272, year: 2012, vol: 118, page: 2603, stat: Journal Article,

Seventeen-gene signature from enriched Her2/Neu mammary tumor-initiating cells predicts clinical outcome for human HER2+:ERalpha- breast cancer
Liu, Jeff C; Voisin, Veronique; Bader, Gary D; Deng, Tao; Pusztai, Lajos; Symmans, William Fraser; Esteva, Francisco J; Egan, Sean E; Zacksenhaus, Eldad
2012 Apr;109(15):5832-5837, Proceedings of the National Academy of Sciences of the United States of America
— id: 517282, year: 2012, vol: 109, page: 5832, stat: Journal Article,

ERbeta1 represses basal-like breast cancer epithelial to mesenchymal transition by destabilizing EGFR
Thomas, Christoforos; Rajapaksa, Gayani; Nikolos, Fotis; Hao, Ruixin; Katchy, Anne; McCollum, Catherine W; Bondesson, Maria; Quinlan, Phil; Thompson, Alastair; Krishnamurthy, Savitri; Esteva, Francisco J; Gustafsson, Jan-Ake
2012 Nov;14(6):R148-R148 R148, Breast cancer research
— id: 517232, year: 2012, vol: 14, page: R148, stat: Journal Article,

Altered expression of sialylated glycoproteins in breast cancer using hydrazide chemistry and mass spectrometry
Tian, Yuan; Esteva, Francisco J; Song, Jin; Zhang, Hui
2012 Jun;11(6):M111.011403-M111.011403 M111.011403, Molecular & cellular proteomics
— id: 517262, year: 2012, vol: 11, page: M111.011403, stat: Journal Article,

Serum CD44 levels and overall survival in patients with HER2-positive breast cancer
Baek, Jong-Min; Jin, Quanri; Ensor, Joe; Boulbes, Delphine R; Esteva, Francisco J
2011 Dec;130(3):1029-1036, Breast cancer research & treatment
— id: 517322, year: 2011, vol: 130, page: 1029, stat: Journal Article,

Herceptin conjugates linked by EDC boost direct tumor cell death via programmed tumor cell necrosis
Hu, Jiemiao; Liu, Xinli; Hughes, Dennis; Esteva, Francisco J; Liu, Bolin; Chandra, Joya; Li, Shulin
2011 ;6(8):e23270-e23270 e23270, PLoS one
— id: 517362, year: 2011, vol: 6, page: e23270, stat: Journal Article,

Biologic and immunologic effects of preoperative trastuzumab for ductal carcinoma in situ of the breast
Kuerer, Henry M; Buzdar, Aman U; Mittendorf, Elizabeth A; Esteva, Francisco J; Lucci, Anthony; Vence, Luis M; Radvanyi, Laszlo; Meric-Bernstam, Funda; Hunt, Kelly K; Symmans, William Fraser
2011 Jan;117(1):39-47, Cancer
— id: 517352, year: 2011, vol: 117, page: 39, stat: Journal Article,

Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy
Morrow, Phuong K; Wulf, Gerburg M; Ensor, Joe; Booser, Daniel J; Moore, Julia A; Flores, Peter R; Xiong, Yan; Zhang, Siyuan; Krop, Ian E; Winer, Eric P; Kindelberger, David W; Coviello, Jeanna; Sahin, Aysegul A; Nunez, Rodolfo; Hortobagyi, Gabriel N; Yu, Dihua; Esteva, Francisco J
2011 Aug;29(23):3126-3132, Journal of clinical oncology
— id: 517332, year: 2011, vol: 29, page: 3126, stat: Journal Article,

Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways
Zhang, Siyuan; Huang, Wen-Chien; Li, Ping; Guo, Hua; Poh, Say-Bee; Brady, Samuel W; Xiong, Yan; Tseng, Ling-Ming; Li, Shau-Hsuan; Ding, Zhaoxi; Sahin, Aysegul A; Esteva, Francisco J; Hortobagyi, Gabriel N; Yu, Dihua
2011 Apr;17(4):461-469, Nature medicine
— id: 517342, year: 2011, vol: 17, page: 461, stat: Journal Article,

PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase
Bartholomeusz, Chandra; Gonzalez-Angulo, Ana M; Kazansky, Anna; Krishnamurthy, Savitri; Liu, Ping; Yuan, Linda X H; Yamasaki, Fumiyuki; Liu, Shuying; Hayashi, Naoki; Zhang, Dongwei; Esteva, Francisco J; Hortobagyi, Gabriel N; Ueno, Naoto T
2010 Mar;16(6):1802-1811, Clinical cancer research
— id: 517422, year: 2010, vol: 16, page: 1802, stat: Journal Article,

PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer
Esteva, Francisco J; Guo, Hua; Zhang, Siyuan; Santa-Maria, Cesar; Stone, Steven; Lanchbury, Jerry S; Sahin, Aysegul A; Hortobagyi, Gabriel N; Yu, Dihua
2010 Oct;177(4):1647-1656, American journal of pathology
— id: 517402, year: 2010, vol: 177, page: 1647, stat: Journal Article,

Molecular predictors of response to trastuzumab and lapatinib in breast cancer
Esteva, Francisco J; Yu, Dihua; Hung, Mien-Chie; Hortobagyi, Gabriel N
2010 Feb;7(2):98-107, Nature reviews. Clinical oncology
— id: 517442, year: 2010, vol: 7, page: 98, stat: Journal Article,

Helicobacter pylori bacteremia with sepsis syndrome
Han, Xiang Y; Tarrand, Jeffrey J; Dickey, Burton F; Esteva, Francisco J
2010 Dec;48(12):4661-4663, Journal of clinical microbiology
— id: 517372, year: 2010, vol: 48, page: 4661, stat: Journal Article,

Heterotrimerization of the growth factor receptors erbB2, erbB3, and insulin-like growth factor-i receptor in breast cancer cells resistant to herceptin
Huang, Xiaoping; Gao, Lizhi; Wang, Shuiliang; McManaman, James L; Thor, Ann D; Yang, Xiaohe; Esteva, Francisco J; Liu, Bolin
2010 Feb;70(3):1204-1214, Cancer research
— id: 517432, year: 2010, vol: 70, page: 1204, stat: Journal Article,

Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells
Jin, Quanri; Yuan, Linda X; Boulbes, Delphine; Baek, Jong Min; Wang, Ying Nai; Gomez-Cabello, Daniel; Hawke, David H; Yeung, Sai Ching; Lee, Mong Hong; Hortobagyi, Gabriel N; Hung, Mien Chie; Esteva, Francisco J
2010 ;12(6):R96-R96 R96, Breast cancer research
— id: 517452, year: 2010, vol: 12, page: R96, stat: Journal Article,

Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials
Juul, Nicolai; Szallasi, Zoltan; Eklund, Aron C; Li, Qiyuan; Burrell, Rebecca A; Gerlinger, Marco; Valero, Vicente; Andreopoulou, Eleni; Esteva, Francisco J; Symmans, W Fraser; Desmedt, Christine; Haibe-Kains, Benjamin; Sotiriou, Christos; Pusztai, Lajos; Swanton, Charles
2010 Apr;11(4):358-365, Lancet oncology
— id: 517412, year: 2010, vol: 11, page: 358, stat: Journal Article,

Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation
Liang, Ke; Esteva, Francisco J; Albarracin, Constance; Stemke-Hale, Katherine; Lu, Yang; Bianchini, Giampaolo; Yang, Ching-Yi; Li, Yong; Li, Xinqun; Chen, Chun-Te; Mills, Gordon B; Hortobagyi, Gabriel N; Mendelsohn, John; Hung, Mien-Chie; Fan, Zhen
2010 Nov;18(5):423-435, Cancer cell
— id: 517382, year: 2010, vol: 18, page: 423, stat: Journal Article,

Blood peptidome-degradome profile of breast cancer
Shen, Yufeng; Tolic, Nikola; Liu, Tao; Zhao, Rui; Petritis, Brianne O; Gritsenko, Marina A; Camp, David G; Moore, Ronald J; Purvine, Samuel O; Esteva, Francisco J; Smith, Richard D
2010 ;5(10):e13133-e13133 e13133, PLoS one
— id: 517392, year: 2010, vol: 5, page: e13133, stat: Journal Article,

Early breast cancer
Benson, John R; Jatoi, Ismail; Keisch, Martin; Esteva, Francisco J; Makris, Andreas; Jordan, V Craig
2009 Apr;373(9673):1463-1479, Lancet
— id: 517502, year: 2009, vol: 373, page: 1463, stat: Journal Article,

Phase I study of prolonged-infusion gemcitabine combined with cyclophosphamide in patients with metastatic carcinoma of the breast: tolerability of an optimal dose schedule
Estephan, Fadi; Valero, Vicente; Esteva, Francisco J; Mejia, Jaime A; Frye, Debra K; Ibrahim, Nuhad K
2009 ;77(1):63-70, Oncology (New York)
— id: 517532, year: 2009, vol: 77, page: 63, stat: Journal Article,

Topoisomerase II{alpha} amplification and anthracycline-based chemotherapy: the jury is still out
Esteva, Francisco J; Hortobagyi, Gabriel N
2009 Jul;27(21):3416-3417, Journal of clinical oncology
— id: 517482, year: 2009, vol: 27, page: 3416, stat: Journal Article,

Even low-level HER2 expression may be associated with worse outcome in node-positive breast cancer
Gilcrease, Michael Z; Woodward, Wendy A; Nicolas, Marlo M; Corley, Lynda J; Fuller, Gregory N; Esteva, Francisco J; Tucker, Susan L; Buchholz, Thomas A
2009 May;33(5):759-767, American journal of surgical pathology
— id: 517492, year: 2009, vol: 33, page: 759, stat: Journal Article,

Minimizing cardiotoxicity while optimizing treatment efficacy with trastuzumab: review and expert recommendations
Martin, Miguel; Esteva, Francisco J; Alba, Emilio; Khandheria, Bijoy; Perez-Isla, Leopoldo; Garcia-Saenz, Jose Angel; Marquez, Antonia; Sengupta, Partho; Zamorano, Jose
2009 Jan;14(1):1-11, Oncologist
— id: 517522, year: 2009, vol: 14, page: 1, stat: Journal Article,

Loss of HER2 amplification following trastuzumab-based neoadjuvant systemic therapy and survival outcomes
Mittendorf, Elizabeth A; Wu, Yun; Scaltriti, Maurizio; Meric-Bernstam, Funda; Hunt, Kelly K; Dawood, Shaheenah; Esteva, Francisco J; Buzdar, Aman U; Chen, Huiqin; Eksambi, Sameena; Hortobagyi, Gabriel N; Baselga, Jose; Gonzalez-Angulo, Ana M
2009 Dec;15(23):7381-7388, Clinical cancer research
— id: 517462, year: 2009, vol: 15, page: 7381, stat: Journal Article,

Recent advances in systemic therapy: Advances in systemic therapy for HER2-positive metastatic breast cancer
Morrow, Phuong Khanh H; Zambrana, Francisco; Esteva, Francisco J
2009 ;11(4):207-207, Breast cancer research
— id: 517512, year: 2009, vol: 11, page: 207, stat: Journal Article,

Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer
Zhang, Dongwei; LaFortune, Tiffany A; Krishnamurthy, Savitri; Esteva, Francisco J; Cristofanilli, Massimo; Liu, Ping; Lucci, Anthony; Singh, Balraj; Hung, Mien-Chie; Hortobagyi, Gabriel N; Ueno, Naoto T
2009 Nov;15(21):6639-6648, Clinical cancer research
— id: 517472, year: 2009, vol: 15, page: 6639, stat: Journal Article,

Serum HER-2/neu and relative resistance to trastuzumab-based therapy in patients with metastatic breast cancer
Ali, Suhail M; Carney, Walter P; Esteva, Francisco J; Fornier, Monica; Harris, Lyndsay; Kostler, Wolfgang J; Lotz, Jean-Pierre; Luftner, Diana; Pichon, Marie-France; Lipton, Allan
2008 Sep;113(6):1294-1301, Cancer
— id: 517592, year: 2008, vol: 113, page: 1294, stat: Journal Article,

Residual risk of breast cancer recurrence 5 years after adjuvant therapy
Brewster, Abenaa M; Hortobagyi, Gabriel N; Broglio, Kristine R; Kau, Shu-Wan; Santa-Maria, Cesar A; Arun, Banu; Buzdar, Aman U; Booser, Daniel J; Valero, Vincente; Bondy, Melissa; Esteva, Francisco J
2008 Aug;100(16):1179-1183, Journal of the National Cancer Institute
— id: 517602, year: 2008, vol: 100, page: 1179, stat: Journal Article,

Emerging agents in the treatment of anthracycline- and taxane-refractory metastatic breast cancer
Dean-Colomb, Windy; Esteva, Francisco J
2008 Apr;35(2 Suppl 2):S31-8; quiz S40, Seminars in oncology
— id: 517662, year: 2008, vol: 35, page: S31, stat: Journal Article,

Her2-positive breast cancer: herceptin and beyond
Dean-Colomb, Windy; Esteva, Francisco J
2008 Dec;44(18):2806-2812, European journal of cancer (1990)
— id: 517562, year: 2008, vol: 44, page: 2806, stat: Journal Article,

Commentary: can circulating HER-2 extracellular domain predict response to trastuzumab in HER-2-negative breast cancer?
Esteva, Francisco J
2008 Apr;13(4):370-372, Oncologist
— id: 517652, year: 2008, vol: 13, page: 370, stat: Journal Article,

Can early response assessment guide neoadjuvant chemotherapy in early-stage breast cancer?
Esteva, Francisco J; Hortobagyi, Gabriel N
2008 Apr;100(8):521-523, Journal of the National Cancer Institute
— id: 517642, year: 2008, vol: 100, page: 521, stat: Journal Article,

Gaining ground on breast cancer
Esteva, Francisco J; Hortobagyi, Gabriel N
2008 Jun;298(6):58-65, Scientific american
— id: 517632, year: 2008, vol: 298, page: 58, stat: Journal Article,

Cross-talk between the ErbB/HER family and the type I insulin-like growth factor receptor signaling pathway in breast cancer
Jin, Quanri; Esteva, Francisco J
2008 Dec;13(4):485-498, Journal of mammary gland biology & neoplasia
— id: 517572, year: 2008, vol: 13, page: 485, stat: Journal Article,

Multidisciplinary strategy for managing cardiovascular risks when treating patients with early breast cancer
Lenihan, Daniel J; Esteva, Francisco J
2008 Dec;13(12):1224-1234, Oncologist
— id: 517582, year: 2008, vol: 13, page: 1224, stat: Journal Article,

Phase I/II study of G3139 (Bcl-2 antisense oligonucleotide) in combination with doxorubicin and docetaxel in breast cancer
Moulder, Stacy L; Symmans, W Fraser; Booser, Daniel J; Madden, Timothy L; Lipsanen, Cindy; Yuan, Linda; Brewster, Abenaa M; Cristofanilli, Massimo; Hunt, Kelly K; Buchholz, Thomas A; Zwiebel, James; Valero, Vicente; Hortobagyi, Gabriel N; Esteva, Francisco J
2008 Dec;14(23):7909-7916, Clinical cancer research
— id: 517542, year: 2008, vol: 14, page: 7909, stat: Journal Article,

National Academy of Clinical Biochemistry laboratory medicine practice guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers
Sturgeon, Catharine M; Duffy, Michael J; Stenman, Ulf-Hakan; Lilja, Hans; Brunner, Nils; Chan, Daniel W; Babaian, Richard; Bast, Robert C Jr; Dowell, Barry; Esteva, Francisco J; Haglund, Caj; Harbeck, Nadia; Hayes, Daniel F; Holten-Andersen, Mads; Klee, George G; Lamerz, Rolf; Looijenga, Leendert H; Molina, Rafael; Nielsen, Hans Jorgen; Rittenhouse, Harry; Semjonow, Axel; Shih, Ie-Ming; Sibley, Paul; Soletormos, Gyorgy; Stephan, Carsten; Sokoll, Lori; Hoffman, Barry R; Diamandis, Eleftherios P
2008 Dec;54(12):e11-e79, Clinical chemistry
— id: 517552, year: 2008, vol: 54, page: e11, stat: Journal Article,

DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight
Weisenberger, Daniel J; Trinh, Binh N; Campan, Mihaela; Sharma, Shikhar; Long, Tiffany I; Ananthnarayan, Suchitra; Liang, Gangning; Esteva, Francisco J; Hortobagyi, Gabriel N; McCormick, Frank; Jones, Peter A; Laird, Peter W
2008 Aug;36(14):4689-4698, Nucleic acids research
— id: 517612, year: 2008, vol: 36, page: 4689, stat: Journal Article,

Activity of lapatinib is independent of EGFR expression level in HER2-overexpressing breast cancer cells
Zhang, Dongwei; Pal, Ashutosh; Bornmann, William G; Yamasaki, Fumiyuki; Esteva, Francisco J; Hortobagyi, Gabriel N; Bartholomeusz, Chandra; Ueno, Naoto T
2008 Jul;7(7):1846-1850, Molecular cancer therapeutics
— id: 517622, year: 2008, vol: 7, page: 1846, stat: Journal Article,

CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer
Esteva, Francisco J; Wang, Jing; Lin, Feng; Mejia, Jaime A; Yan, Kai; Altundag, Kadri; Valero, Vicente; Buzdar, Aman U; Hortobagyi, Gabriel N; Symmans, W Fraser; Pusztai, Lajos
2007 ;9(6):R87-R87 R87, Breast cancer research
— id: 517712, year: 2007, vol: 9, page: R87, stat: Journal Article,

Novel clinical trial designs for treatment of ductal carcinoma in situ of the breast with trastuzumab (herceptin)
Gonzalez, Ricardo J; Buzdar, Aman U; Fraser Symmans, W; Yen, Tina W; Broglio, Kristine R; Lucci, Anthony; Esteva, Francisco J; Yin, Guosheng; Kuerer, Henry M
2007 Jan-Feb;13(1):72-75, Breast journal
— id: 517722, year: 2007, vol: 13, page: 72, stat: Journal Article,

Adenovirus type 5 E1A gene therapy for ovarian clear cell carcinoma: a potential treatment strategy
Itamochi, Hiroaki; Kigawa, Junzo; Kanamori, Yasunobu; Oishi, Tetsuro; Bartholomeusz, Chandra; Nahta, Rita; Esteva, Francisco J; Sneige, Nour; Terakawa, Naoki; Ueno, Naoto T
2007 Jan;6(1):227-235, Molecular cancer therapeutics
— id: 517742, year: 2007, vol: 6, page: 227, stat: Journal Article,

The use of HER2 modulation in the adjuvant setting
Johnson, Peter H; Esteva, Francisco J
2007 Jan;9(1):9-16, Current oncology reports
— id: 517732, year: 2007, vol: 9, page: 9, stat: Journal Article,

Preclinical testing of clinically applicable strategies for overcoming trastuzumab resistance caused by PTEN deficiency
Lu, Chien-Hsing; Wyszomierski, Shannon L; Tseng, Ling-Ming; Sun, Meng-Hong; Lan, Keng-Hsueh; Neal, Christopher L; Mills, Gordon B; Hortobagyi, Gabriel N; Esteva, Francisco J; Yu, Dihua
2007 Oct;13(19):5883-5888, Clinical cancer research
— id: 517672, year: 2007, vol: 13, page: 5883, stat: Journal Article,

Kinetics of serum HER-2/neu changes in patients with HER-2-positive primary breast cancer after initiation of primary chemotherapy
Mazouni, Chafika; Hall, Angeline; Broglio, Kristine; Fritsche, Herbert; Andre, Fabrice; Esteva, Francisco J; Hortobagyi, Gabriel N; Buzdar, Aman U; Pusztai, Lajos; Cristofanilli, Massimo
2007 Feb;109(3):496-501, Cancer
— id: 517692, year: 2007, vol: 109, page: 496, stat: Journal Article,

Lapatinib induces apoptosis in trastuzumab-resistant breast cancer cells: effects on insulin-like growth factor I signaling
Nahta, Rita; Yuan, Linda X H; Du, Yi; Esteva, Francisco J
2007 Feb;6(2):667-674, Molecular cancer therapeutics
— id: 517702, year: 2007, vol: 6, page: 667, stat: Journal Article,

Are there racial differences in breast cancer treatments and clinical outcomes for women treated at M.D. Anderson Cancer Center?
Shen, Yu; Dong, Wenli; Esteva, Francisco J; Kau, Shu-Wan; Theriault, Richard L; Bevers, Therese B
2007 May;102(3):347-356, Breast cancer research & treatment
— id: 517682, year: 2007, vol: 102, page: 347, stat: Journal Article,

Tamoxifen-related vasculitis
Baptista, Mauricio Z; Prieto, Victor G; Chon, Susan; Hortobagyi, Gabriel N; Esteva, Francisco J
2006 Jul;24(21):3504-3505, Journal of clinical oncology
— id: 517782, year: 2006, vol: 24, page: 3504, stat: Journal Article,

Adjuvant therapy with trastuzumab for HER-2/neu-positive breast cancer
Gonzalez-Angulo, Ana M; Hortobagyi, Gabriel N; Esteva, Francisco J
2006 Sep;11(8):857-867, Oncologist
— id: 517772, year: 2006, vol: 11, page: 857, stat: Journal Article,

Downregulation of the cyclin-dependent kinase inhibitor p27kip1 might correlate with poor disease-free and overall survival in inflammatory breast cancer
Gonzalez-Angulo, Ana Maria; Guarneri, Valentina; Gong, Yun; Cristofanilli, Massimo; Morales-Vasquez, Flavia; Sneige, Nour; Hortobagyi, Gabriel N; Esteva, Francisco J
2006 Oct;7(4):326-330, Clinical breast cancer
— id: 517752, year: 2006, vol: 7, page: 326, stat: Journal Article,

Long-term cardiac tolerability of trastuzumab in metastatic breast cancer: the M.D. Anderson Cancer Center experience
Guarneri, Valentina; Lenihan, Daniel J; Valero, Vicente; Durand, Jean-Bernard; Broglio, Kristine; Hess, Kenneth R; Michaud, Laura Boehnke; Gonzalez-Angulo, Ana M; Hortobagyi, Gabriel N; Esteva, Francisco J
2006 Sep;24(25):4107-4115, Journal of clinical oncology
— id: 517762, year: 2006, vol: 24, page: 4107, stat: Journal Article,

HER2 therapy: molecular mechanisms of trastuzumab resistance
Nahta, Rita; Esteva, Francisco J
2006 ;8(6):215-215, Breast cancer research
— id: 517842, year: 2006, vol: 8, page: 215, stat: Journal Article,

Herceptin: mechanisms of action and resistance
Nahta, Rita; Esteva, Francisco J
2006 Feb;232(2):123-138, Cancer letters
— id: 517822, year: 2006, vol: 232, page: 123, stat: Journal Article,

Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer
Nahta, Rita; Yu, Dihua; Hung, Mien-Chie; Hortobagyi, Gabriel N; Esteva, Francisco J
2006 May;3(5):269-280, Nature clinical practice. Oncology
— id: 517802, year: 2006, vol: 3, page: 269, stat: Journal Article,

B cell translocation gene 1 contributes to antisense Bcl-2-mediated apoptosis in breast cancer cells
Nahta, Rita; Yuan, Linda X H; Fiterman, Derek J; Zhang, Li; Symmans, W Fraser; Ueno, Naoto T; Esteva, Francisco J
2006 Jun;5(6):1593-1601, Molecular cancer therapeutics
— id: 517792, year: 2006, vol: 5, page: 1593, stat: Journal Article,

Concomitant versus sequential chemotherapy in the treatment of early-stage and metastatic breast cancer
Ocana, Alberto; Hortobagyi, Gabriel N; Esteva, Francisco J
2006 Feb;6(6):495-504, Clinical breast cancer
— id: 517832, year: 2006, vol: 6, page: 495, stat: Journal Article,

Continued use of trastuzumab (herceptin) after progression on prior trastuzumab therapy in HER-2-positive metastatic breast cancer
Pusztai, Lajos; Esteva, Francisco J
2006 Mar;24(2):187-191, Cancer investigation
— id: 517812, year: 2006, vol: 24, page: 187, stat: Journal Article,

Monoclonal antibody-based targeted therapy in breast cancer
Altundag, Kadri; Esteva, Francisco J; Arun, Banu
2005 Mar;5(2):99-106, Current medicinal chemistry. Anti-cancer agents
— id: 517932, year: 2005, vol: 5, page: 99, stat: Journal Article,

Bcl-2 antisense oligonucleotide overcomes resistance to E1A gene therapy in a low HER2-expressing ovarian cancer xenograft model
Bartholomeusz, Chandra; Itamochi, Hiroaki; Yuan, Linda X H; Esteva, Francisco J; Wood, Christopher G; Terakawa, Naoki; Hung, Mien-Chie; Ueno, Naoto T
2005 Sep;65(18):8406-8413, Cancer research
— id: 517902, year: 2005, vol: 65, page: 8406, stat: Journal Article,

The nuclear transcription factor kappaB/bcl-2 pathway correlates with pathologic complete response to doxorubicin-based neoadjuvant chemotherapy in human breast cancer
Buchholz, Thomas A; Garg, Amit K; Chakravarti, Nitin; Aggarwal, Bharat B; Esteva, Francisco J; Kuerer, Henry M; Singletary, S Eva; Hortobagyi, Gabriel N; Pusztai, Lajos; Cristofanilli, Massimo; Sahin, Aysegul A
2005 Dec;11(23):8398-8402, Clinical cancer research
— id: 517862, year: 2005, vol: 11, page: 8398, stat: Journal Article,

Epidermal growth factor receptor expression correlates with poor survival in patients who have breast carcinoma treated with doxorubicin-based neoadjuvant chemotherapy
Buchholz, Thomas A; Tu, Xiaoyu; Ang, K Kian; Esteva, Francisco J; Kuerer, Henry M; Pusztai, Lajos; Cristofanilli, Massimo; Singletary, S Eva; Hortobagyi, Gabriel N; Sahin, Aysegul A
2005 Aug;104(4):676-681, Cancer
— id: 517912, year: 2005, vol: 104, page: 676, stat: Journal Article,

Clinical utility of serum HER2/neu in monitoring and prediction of progression-free survival in metastatic breast cancer patients treated with trastuzumab-based therapies
Esteva, Francisco J; Cheli, Carol D; Fritsche, Herbert; Fornier, Monica; Slamon, Dennis; Thiel, Robert P; Luftner, Diana; Ghani, Farooq
2005 ;7(4):R436-R443, Breast cancer research
— id: 517942, year: 2005, vol: 7, page: R436, stat: Journal Article,

Optimizing outcomes in HER2-positive breast cancer: the molecular rationale
Esteva, Francisco J; Pusztai, Lajos
2005 Nov;19(13 Suppl 5):5-16, Oncology
— id: 517872, year: 2005, vol: 19, page: 5, stat: Journal Article,

Optimizing outcomes in HER2-positive breast cancer: the molecular rationale
Esteva, Francisco J; Pusztai, Lajos
2005 Nov;19(13 Suppl 5):4-4, Oncology
— id: 517882, year: 2005, vol: 19, page: 4, stat: Journal Article,

Prognostic role of a multigene reverse transcriptase-PCR assay in patients with node-negative breast cancer not receiving adjuvant systemic therapy
Esteva, Francisco J; Sahin, Aysegul A; Cristofanilli, Massimo; Coombes, Kevin; Lee, Sang-Joon; Baker, Joffre; Cronin, Maureen; Walker, Michael; Watson, Drew; Shak, Steven; Hortobagyi, Gabriel N
2005 May;11(9):3315-3319, Clinical cancer research
— id: 517922, year: 2005, vol: 11, page: 3315, stat: Journal Article,

Potential role of mammalian target of rapamycin inhibitors in breast cancer therapy
Meric-Bernstam, Funda; Esteva, Francisco J
2005 Oct;6(4):357-360, Clinical breast cancer
— id: 517892, year: 2005, vol: 6, page: 357, stat: Journal Article,

Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells
Nahta, Rita; Yuan, Linda X H; Zhang, Bing; Kobayashi, Ryuji; Esteva, Francisco J
2005 Dec;65(23):11118-11128, Cancer research
— id: 517852, year: 2005, vol: 65, page: 11118, stat: Journal Article,

Monoclonal antibodies, small molecules, and vaccines in the treatment of breast cancer
Esteva, Francisco J
2004 ;9 Suppl 3:4-9, Oncologist
— id: 518072, year: 2004, vol: 9 Suppl 3, page: 4, stat: Journal Article,

Prognostic molecular markers in early breast cancer
Esteva, Francisco J; Hortobagyi, Gabriel N
2004 ;6(3):109-118, Breast cancer research
— id: 518042, year: 2004, vol: 6, page: 109, stat: Journal Article,

Prognostic significance of phosphorylated P38 mitogen-activated protein kinase and HER-2 expression in lymph node-positive breast carcinoma
Esteva, Francisco J; Sahin, Aysegul A; Smith, Terry L; Yang, Ying; Pusztai, Lajos; Nahta, Rita; Buchholz, Thomas A; Buzdar, Aman U; Hortobagyi, Gabriel N; Bacus, Sarah S
2004 Feb;100(3):499-506, Cancer
— id: 518022, year: 2004, vol: 100, page: 499, stat: Journal Article,

Lack of association between amplification of her-2 and response to preoperative taxanes in patients with breast carcinoma
Gonzalez-Angulo, Ana M; Krishnamurthy, Savitri; Yamamura, Yuko; Broglio, Kristine R; Pusztai, Lajos; Buzdar, Aman U; Hortobagyi, Gabriel N; Esteva, Francisco J
2004 Jul;101(2):258-263, Cancer
— id: 517972, year: 2004, vol: 101, page: 258, stat: Journal Article,

Neoadjuvant chemotherapy
Green, Marjorie C; Esteva, Francisco J; Hortobagyi, Gabriel N
2004 ;21:23-31, Breast disease
— id: 518052, year: 2004, vol: 21, page: 23, stat: Journal Article,

Expression of cell cycle inhibitor p27Kip1 and its inactivator Jab1 in melanocytic lesions
Ivan, Doina; Diwan, A Hafeez; Esteva, Francisco J; Prieto, Victor G
2004 Jul;17(7):811-818, Modern pathology
— id: 517982, year: 2004, vol: 17, page: 811, stat: Journal Article,

PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
Nagata, Yoichi; Lan, Keng-Hsueh; Zhou, Xiaoyan; Tan, Ming; Esteva, Francisco J; Sahin, Aysegul A; Klos, Kristine S; Li, Ping; Monia, Brett P; Nguyen, Nina T; Hortobagyi, Gabriel N; Hung, Mien-Chie; Yu, Dihua
2004 Aug;6(2):117-127, Cancer cell
— id: 517952, year: 2004, vol: 6, page: 117, stat: Journal Article,

In vitro effects of trastuzumab and vinorelbine in trastuzumab-resistant breast cancer cells
Nahta, Rita; Esteva, Francisco J
2004 Feb;53(2):186-190, Cancer chemotherapy & pharmacology
— id: 518032, year: 2004, vol: 53, page: 186, stat: Journal Article,

The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells
Nahta, Rita; Hung, Mien-Chie; Esteva, Francisco J
2004 Apr;64(7):2343-2346, Cancer research
— id: 518012, year: 2004, vol: 64, page: 2343, stat: Journal Article,

P27(kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells
Nahta, Rita; Takahashi, Takeshi; Ueno, Naoto T; Hung, Mien-Chie; Esteva, Francisco J
2004 Jun;64(11):3981-3986, Cancer research
— id: 517992, year: 2004, vol: 64, page: 3981, stat: Journal Article,

Pharmacoproteomic analysis of prechemotherapy and postchemotherapy plasma samples from patients receiving neoadjuvant or adjuvant chemotherapy for breast carcinoma
Pusztai, Lajos; Gregory, Betsy W; Baggerly, Keith A; Peng, Bo; Koomen, John; Kuerer, Henry M; Esteva, Francisco J; Symmans, W Fraser; Wagner, Peter; Hortobagyi, Gabriel N; Laronga, Christine; Semmes, O John; Wright, George L Jr; Drake, Richard R; Vlahou, Antonia
2004 May;100(9):1814-1822, Cancer
— id: 518002, year: 2004, vol: 100, page: 1814, stat: Journal Article,

Expression of BAG-1 and BcL-2 proteins before and after neoadjuvant chemotherapy of locally advanced breast cancer
Pusztai, Lajos; Krishnamurti, Savitri; Perez Cardona, Jorge; Sneige, Nour; Esteva, Francisco J; Volchenok, Marina; Breitenfelder, Patricia; Kau, Shu-Wan; Takayama, Shin; Krajewski, Stanislaw; Reed, John C; Bast, Robert C Jr; Hortobagyi, Gabriel N
2004 ;22(2):248-256, Cancer investigation
— id: 518062, year: 2004, vol: 22, page: 248, stat: Journal Article,

Pathologic changes in breast cancer following neoadjuvant chemotherapy: implications for the assessment of response
Rajan, Radhika; Esteva, Francisco J; Symmans, W Fraser
2004 Aug;5(3):235-238, Clinical breast cancer
— id: 517962, year: 2004, vol: 5, page: 235, stat: Journal Article,

Chemotherapy-induced apoptosis and Bcl-2 levels correlate with breast cancer response to chemotherapy
Buchholz, Thomas A; Davis, Darren W; McConkey, David J; Symmans, W Fraser; Valero, Vicente; Jhingran, Anuja; Tucker, Susan L; Pusztai, Lajos; Cristofanilli, Massimo; Esteva, Francisco J; Hortobagyi, Gabriel N; Sahin, Aysegul A
2003 Jan-Feb;9(1):33-41, Cancer journal
— id: 518192, year: 2003, vol: 9, page: 33, stat: Journal Article,

Multicenter phase II study of oral bexarotene for patients with metastatic breast cancer
Esteva, Francisco J; Glaspy, John; Baidas, Said; Laufman, Leslie; Hutchins, Laura; Dickler, Maura; Tripathy, Debu; Cohen, Roger; DeMichele, Angela; Yocum, Richard C; Osborne, C Kent; Hayes, Daniel F; Hortobagyi, Gabriel N; Winer, Eric; Demetri, George D
2003 Mar;21(6):999-1006, Journal of clinical oncology
— id: 518172, year: 2003, vol: 21, page: 999, stat: Journal Article,

A Phase II study of intravenous exatecan mesylate (DX-8951f) administered daily for 5 days every 3 weeks to patients with metastatic breast carcinoma
Esteva, Francisco J; Rivera, Edgardo; Cristofanilli, Massimo; Valero, Vicente; Royce, Melanie; Duggal, Anil; Colucci, Philippe; DeJager, Robert; Hortobagyi, Gabriel N
2003 Sep;98(5):900-907, Cancer
— id: 518122, year: 2003, vol: 98, page: 900, stat: Journal Article,

Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer
Esteva, Francisco J; Sahin, Aysegul A; Rassidakis, George Z; Yuan, Linda X H; Smith, Terry L; Yang, Ying; Gilcrease, Michael Z; Cristofanilli, Massimo; Nahta, Rita; Pusztai, Lajos; Claret, Francois-Xavier
2003 Nov;9(15):5652-5659, Clinical cancer research
— id: 518082, year: 2003, vol: 9, page: 5652, stat: Journal Article,

Bcl-2 antisense oligonucleotides: a potential novel strategy for the treatment of breast cancer
Nahta, Rita; Esteva, Francisco J
2003 Oct;30(5 Suppl 16):143-149, Seminars in oncology
— id: 518102, year: 2003, vol: 30, page: 143, stat: Journal Article,

HER-2-targeted therapy: lessons learned and future directions
Nahta, Rita; Esteva, Francisco J
2003 Nov;9(14):5078-5084, Clinical cancer research
— id: 518092, year: 2003, vol: 9, page: 5078, stat: Journal Article,

Growth factor receptors in breast cancer: potential for therapeutic intervention
Nahta, Rita; Hortobagyi, Gabriel N; Esteva, Francisco J
2003 ;8(1):5-17, Oncologist
— id: 518202, year: 2003, vol: 8, page: 5, stat: Journal Article,

Novel pharmacological approaches in the treatment of breast cancer
Nahta, Rita; Hortobagyi, Gabriel N; Esteva, Francisco J
2003 Jun;12(6):909-921, Expert opinion on investigational drugs
— id: 518142, year: 2003, vol: 12, page: 909, stat: Journal Article,

Signal transduction inhibitors in the treatment of breast cancer
Nahta, Rita; Hortobagyi, Gabriel N; Esteva, Francisco J
2003 May;3(3):201-216, Current medicinal chemistry. Anti-cancer agents
— id: 518152, year: 2003, vol: 3, page: 201, stat: Journal Article,

Gene expression profiles obtained from fine-needle aspirations of breast cancer reliably identify routine prognostic markers and reveal large-scale molecular differences between estrogen-negative and estrogen-positive tumors
Pusztai, Lajos; Ayers, Mark; Stec, James; Clark, Edward; Hess, Kenneth; Stivers, David; Damokosh, Andrew; Sneige, Nour; Buchholz, Thomas A; Esteva, Francisco J; Arun, Banu; Cristofanilli, Massimo; Booser, Daniel; Rosales, Marguerite; Valero, Vicente; Adams, Constantine; Hortobagyi, Gabriel N; Symmans, W Fraser
2003 Jul;9(7):2406-2415, Clinical cancer research
— id: 518132, year: 2003, vol: 9, page: 2406, stat: Journal Article,

Molecular profiles of invasive mucinous and ductal carcinomas of the breast: a molecular case study
Pusztai, Lajos; Sotiriou, Christos; Buchholz, Thomas A; Meric, Funda; Symmans, W Fraser; Esteva, Francisco J; Sahin, Aysegul; Liu, Edison T; Hortobagi, Gabriel N
2003 Mar;141(2):148-153, Cancer genetics & cytogenetics
— id: 518182, year: 2003, vol: 141, page: 148, stat: Journal Article,

Phase I and II study of exisulind in combination with capecitabine in patients with metastatic breast cancer
Pusztai, Lajos; Zhen, Jim Hou; Arun, Banu; Rivera, Edgardo; Whitehead, Clark; Thompson, W Joseph; Nealy, Kimberly M; Gibbs, Amy; Symmans, W Fraser; Esteva, Francisco J; Booser, Daniel; Murray, James L; Valero, Vicente; Smith, Terry L; Hortobagyi, Gabriel N
2003 Sep;21(18):3454-3461, Journal of clinical oncology
— id: 518112, year: 2003, vol: 21, page: 3454, stat: Journal Article,

Correlation between HER-2 expression and response to neoadjuvant chemotherapy with 5-fluorouracil, doxorubicin, and cyclophosphamide in patients with breast carcinoma
Zhang, Fan; Yang, Ying; Smith, Terry; Kau, Shu-Wan; McConathy, Judy M; Esteva, Francisco J; Kuerer, Henry M; Symmans, W Fraser; Buzdar, Aman U; Hortobagyi, Gabriel N; Pusztai, Lajos
2003 Apr;97(7):1758-1765, Cancer
— id: 518162, year: 2003, vol: 97, page: 1758, stat: Journal Article,

Phase II study of liposomal annamycin in the treatment of doxorubicin-resistant breast cancer
Booser, Daniel J; Esteva, Francisco J; Rivera, Edgardo; Valero, Vicente; Esparza-Guerra, Laura; Priebe, Waldemar; Hortobagyi, Gabriel N
2002 Jul;50(1):6-8, Cancer chemotherapy & pharmacology
— id: 518232, year: 2002, vol: 50, page: 6, stat: Journal Article,

Breast carcinoma treatment received by women with disabilities compared with women without disabilities
Caban, Mabel E; Nosek, Margaret A; Graves, Daniel; Esteva, Francisco J; McNeese, Marsha
2002 Mar;94(5):1391-1396, Cancer
— id: 518292, year: 2002, vol: 94, page: 1391, stat: Journal Article,

Canalicular stenosis secondary to weekly versus every-3-weeks docetaxel in patients with metastatic breast cancer
Esmaeli, Bita; Hortobagyi, Gabriel N; Esteva, Francisco J; Booser, Daniel; Ahmadi, M Amir; Rivera, Edgardo; Arbuckle, Rebecca; Delpassand, Ebrahim; Guerra, Laura; Valero, Vicente
2002 Jun;109(6):1188-1191, Ophthalmology
— id: 518262, year: 2002, vol: 109, page: 1188, stat: Journal Article,

The current status of docetaxel for metastatic breast cancer
Esteva, Francisco J
2002 Jun;16(6 Suppl 6):17-26, Oncology
— id: 518252, year: 2002, vol: 16, page: 17, stat: Journal Article,

Molecular prognostic factors for breast cancer metastasis and survival
Esteva, Francisco J; Sahin, Aysegul A; Cristofanilli, Massimo; Arun, Banu; Hortobagyi, Gabriel N
2002 Oct;12(4):319-328, Seminars in radiation oncology
— id: 518212, year: 2002, vol: 12, page: 319, stat: Journal Article,

Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer
Esteva, Francisco J; Valero, Vicente; Booser, Daniel; Guerra, Laura T; Murray, James L; Pusztai, Lajos; Cristofanilli, Massimo; Arun, Banu; Esmaeli, Bita; Fritsche, Herbert A; Sneige, Nour; Smith, Terry L; Hortobagyi, Gabriel N
2002 Apr;20(7):1800-1808, Journal of clinical oncology
— id: 518282, year: 2002, vol: 20, page: 1800, stat: Journal Article,

Lack of activity of stealth liposomal doxorubicin in the treatment of patients with anthracycline-resistant breast cancer
Rivera, Edgardo; Valero, Vicente; Esteva, Francisco J; Syrewicz, Laura; Cristofanilli, Massimo; Rahman, Zia; Booser, Daniel J; Hortobagyi, Gabriel N
2002 Apr;49(4):299-302, Cancer chemotherapy & pharmacology
— id: 518272, year: 2002, vol: 49, page: 299, stat: Journal Article,

Her2/neu induces all-trans retinoic acid (ATRA) resistance in breast cancer cells
Tari, Ana M; Lim, Soo-Jeong; Hung, Mien-Chie; Esteva, Francisco J; Lopez-Berestein, Gabriel
2002 Aug;21(34):5224-5232, Oncogene
— id: 518222, year: 2002, vol: 21, page: 5224, stat: Journal Article,

Assessment of histologic features and expression of biomarkers in predicting pathologic response to anthracycline-based neoadjuvant chemotherapy in patients with breast carcinoma
Wang, Jianzhou; Buchholz, Thomas A; Middleton, Lavinia P; Allred, D Craig; Tucker, Susan L; Kuerer, Henry M; Esteva, Francisco J; Hortobagyi, Gabriel N; Sahin, Aysegul A
2002 Jun;94(12):3107-3114, Cancer
— id: 518242, year: 2002, vol: 94, page: 3107, stat: Journal Article,